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VEXAS syndrome is characterized by inflammasome activation and monocyte dysregulation
Olivier Kosmider
,
Céline Possémé
,
Marie Templé
,
Aurélien Corneau
,
Francesco Carbone
et al.
Article dans une revue
(article de synthèse)
pasteur-04467897
v1
|
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BMP9 is a key player in endothelial identity and its loss is sufficient to induce arteriovenous malformations
Agnes Desroches-Castan
,
Dzenis Koca
,
Hequn Liu
,
Caroline Roelants
,
Léa Resmini
et al.
Article dans une revue
hal-04543282
v1
|
|
Vasorin as an actor of bone turnover?
Caroline Andrique
,
Anne Laure Bonnet
,
Julien Dang
,
Julie Lesieur
,
A. Michaela Krautzberger
et al.
Article dans une revue
hal-04516437
v1
|
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Podocyte Injury in Diabetic Kidney Disease in Mouse Models Involves TRPC6-mediated Calpain Activation Impairing Autophagy
Yann Salemkour
,
Dilemin Yildiz
,
Léa Dionet
,
Kim A.T. Verheijden
,
Ryuta Saito
et al.
Article dans une revue
hal-04361228
v1
|
|
More rapid blood interferon α2 decline in fatal versus surviving COVID-19 patients
Candie Joly
,
Delphine Desjardins
,
Raphael Porcher
,
Hélène Péré
,
Thomas Bruneau
et al.
Article dans une revue
hal-04361184
v1
|
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Endothelin blockade prevents the long-term cardiovascular and renal sequelae of acute kidney injury in mice
Alicja Czopek
,
Rebecca Moorhouse
,
Peter Gallacher
,
Dan Pugh
,
Jessica Ivy
et al.
Article dans une revue
hal-03918227
v1
|
|
Should we consider calcimimetics as a therapeutic option for nephrotic syndrome?
Olivia Lenoir
,
Pierre-Louis Tharaux
Article dans une revue
inserm-03788305
v1
|
|
MicroRNAs in kidney injury and disease
Nassim Mahtal
,
Olivia Lenoir
,
Claire Tinel
,
Dany Anglicheau
,
Pierre-Louis Tharaux
Article dans une revue
inserm-03787575
v1
|
|
Behavioural immune landscapes of inflammation
Georgiana Crainiciuc
,
Miguel Palomino-Segura
,
Miguel Molina-Moreno
,
Jon Sicilia
,
David Aragones
et al.
Article dans une revue
hal-04764101
v1
|
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Vasorin Plays a Critical Role in Vascular Smooth Muscle Cells and Arterial Functions.
Loïc Louvet
,
Gaëlle Lenglet
,
A. Michaela Krautzberger
,
Romuald Mentaverri
,
Frédéric Hague
et al.
Article dans une revue
hal-03740510
v1
|
|
Effect of interleukin-6 receptor antagonists in critically ill adult patients with COVID-19 pneumonia: two randomised controlled trials of the CORIMUNO-19 Collaborative Group
Olivier Hermine
,
Xavier Mariette
,
Raphael Porcher
,
Matthieu Resche-Rigon
,
Pierre-Louis Tharaux
et al.
Article dans une revue
inserm-03787577
v1
|
|
Tocilizumab plus dexamethasone versus dexamethasone in patients with moderate-to-severe COVID-19 pneumonia: A randomised clinical trial from the CORIMUNO-19 study group
Olivier Hermine
,
Xavier Mariette
,
Raphael Porcher
,
Felix Djossou
,
Yann Nguyen
et al.
Article dans une revue
inserm-03787576
v1
|
|
FIBER-ML, an Open-Source Supervised Machine Learning Tool for Quantification of Fibrosis in Tissue Sections
Caterina Facchin
,
Anais Certain
,
Thulaciga Yoganathan
,
Clement Delacroix
,
Alicia Arevalo Garcia
et al.
Article dans une revue
inserm-03788337
v1
|
|
Severe COVID-19 is associated with hyperactivation of the alternative complement pathway
Jeremy Boussier
,
Nader Yatim
,
Armance Marchal
,
Jérôme Hadjadj
,
Bruno Charbit
et al.
Article dans une revue
pasteur-03477606
v1
|
|
ScoMorphoFISH: A deep learning enabled toolbox for single‐cell single‐mRNA quantification and correlative (ultra‐)morphometry
Florian Siegerist
,
Eleonora Hay
,
Juan Saydou Dikou
,
Marion Pollheimer
,
Anja Büscher
et al.
Article dans une revue
inserm-03788311
v1
|
|
The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies
Jérémy Manry
,
Paul Bastard
,
Adrian Gervais
,
Tom Le Voyer
,
Jérémie Rosain
et al.
Proceedings of the National Academy of Sciences of the United States of America, 2022, 119 (21), pp.349-363. ⟨10.1073/pnas.2200413119⟩
Article dans une revue
hal-03856619
v2
|
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Differential association between inflammatory cytokines and multiorgan dysfunction in COVID-19 patients with obesity
Marie-Agnès Dragon-Durey
,
Xiaoyi Chen
,
Amos Kirilovsky
,
Nadine Ben Hamouda
,
Carine El Sissy
et al.
Article dans une revue
hal-03239731
v1
|
|
Parietal epithelial cell dysfunction in crescentic glomerulonephritis
Milagros N Wong
,
Pierre-Louis Tharaux
,
Florian Grahammer
,
Victor G Puelles
Article dans une revue
hal-04601799
v1
|
|
Effect of anakinra versus usual care in adults in hospital with COVID-19 and mild-to-moderate pneumonia (CORIMUNO-ANA-1): a randomised controlled trial
Pierre-Louis Tharaux
,
Gilles Pialoux
,
Arthur Pavot
,
Xavier Mariette
,
Olivier Hermine
et al.
Article dans une revue
hal-03579180
v1
|
|
Calpastatin prevents Angiotensin II–mediated podocyte injury through maintenance of autophagy
Imane Bensaada
,
Blaise Robin
,
Joëlle Perez
,
Yann Salemkour
,
Anna Chipont
et al.
Article dans une revue
hal-03918903
v1
|
|
Sunitinib-induced cardiac hypertrophy and the endothelin axis
Joevin Sourdon
,
Caterina Facchin
,
Anaïs Certain
,
Thomas Viel
,
Blaise Robin
et al.
Article dans une revue
hal-03430957
v1
|
|
Identification of driver genes for critical forms of COVID-19 in a deeply phenotyped young patient cohort
Raphael Carapito
,
Richard Li
,
Julie Helms
,
Christine Carapito
,
Sharvari Gujja
et al.
Article dans une revue
hal-03436053
v1
|
|
Effect of Tocilizumab vs Usual Care in Adults Hospitalized With COVID-19 and Moderate or Severe Pneumonia
Olivier Hermine
,
Xavier Mariette
,
Pierre-Louis Tharaux
,
Matthieu Resche-Rigon
,
Raphaël Porcher
et al.
Article dans une revue
hal-03579175
v1
|
|
3D-printed protected face shields for health care workers in Covid-19 pandemic
Vincent Lemarteleur
,
Vincent Fouquet
,
Stéphane Le Goff
,
Laurent Tapie
,
Pascal Morenton
et al.
Article dans une revue
hal-03249487
v1
|
|
Endothelial S1P 1 Signaling Counteracts Infarct Expansion in Ischemic Stroke
Anja Nitzsche
,
Marine Poittevin
,
Ammar Benarab
,
Philippe Bonnin
,
Giuseppe Faraco
et al.
Article dans une revue
hal-03886183
v1
|
|
Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths
Paul Bastard
,
Adrian Gervais
,
Tom Le Voyer
,
Jeremie Rosain
,
Quentin Philippot
et al.
Article dans une revue
hal-03358792
v1
|
|
The proteome of neutrophils in sickle cell disease reveals an unexpected activation of interferon alpha signaling pathway
Patricia Hermand
,
Slim Azouzi
,
Emilie-Fleur Gautier
,
François Guillonneau
,
Vincent Bondet
et al.
Article dans une revue
pasteur-02505633
v1
|
|
Deletion of the myeloid endothelin-B receptor confers long-term protection from angiotensin II-mediated kidney, eye and vessel injury
Léa Guyonnet
,
Alicja Czopek
,
Tariq Farrah
,
Véronique Baudrie
,
Philippe Bonnin
et al.
Article dans une revue
hal-03832377
v1
|
|
Deletion of the myeloid endothelin-B receptor confers long-term protection from angiotensin II-mediated kidney, eye and vessel injury
Léa Guyonnet
,
Alicja Czopek
,
Tariq E Farrah
,
Véronique Baudrie
,
Philippe Bonnin
et al.
Article dans une revue
hal-03268543
v1
|
|
Histamine provides an original vista on cardiorenal syndrome
Pierre-Louis Tharaux
Proceedings of the National Academy of Sciences of the United States of America, 2020, 117 (11), pp.5550-5552. ⟨10.1073/pnas.2001336117⟩
Article dans une revue
hal-04764092
v1
|
|
Podocytes maintain high basal levels of autophagy independent of mtor signaling
Tillmann Bork
,
Wei Liang
,
Kosuke Yamahara
,
Philipp Lee
,
Zhejia Tian
et al.
Article dans une revue
hal-03832381
v1
|
|
Metabolomic Profiling of Plasma and Erythrocytes in Sickle Mice Points to Altered Nociceptive Pathways
Klétigui Casimir Dembélé
,
Thomas Mintz
,
Charlotte Veyrat-Durebex
,
Floris Chabrun
,
Stéphanie Chupin
et al.
Article dans une revue
hal-02974118
v1
|
|
Rôle pathogénique de l’expression anormale de la tétraspanine CD9 par les cellules épithéliales pariétales dans les glomérulopathies extracapillaires
Hélène Lazareth
,
Olivia Lenoir
,
Carole Hénique
,
Cédric Bouzigues
,
Claude Boucheix
et al.
Article dans une revue
hal-02960790
v1
|
|
Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients
Jérôme Hadjadj
,
Nader Yatim
,
Laura Barnabei
,
Aurélien Corneau
,
Jeremy Boussier
et al.
Article dans une revue
pasteur-02900830
v1
|
|
A novel role for myeloid endothelin-B receptors in hypertension
Alicja Czopek
,
Rebecca Moorhouse
,
Léa Guyonnet
,
Tariq Farrah
,
Olivia Lenoir
et al.
Article dans une revue
inserm-02439065
v1
|
|
Local miscommunications between glomerular cells as potential therapeutic targets for crescentic glomerulonephritides
Carole Hénique
,
Olivia Lenoir
,
Alexandre Karras
,
Pierre-Louis Tharaux
Article dans une revue
hal-03485068
v1
|
|
L’hypertension artérielle maligne , un futur prometteur
Romain Boulestreau
,
Antoine Cremer
,
Aurelien Lorthioir
,
Sébastien Rubin
,
Pierre-Louis Tharaux
et al.
Article dans une revue
hal-03117380
v1
|
|
A novel role for myeloid endothelin-B receptors in hypertension
Alicja Czopek
,
Rebecca Moorhouse
,
Léa Guyonnet
,
Tariq Farrah
,
Olivia Lenoir
et al.
Article dans une revue
hal-03918917
v1
|
|
The tetraspanin CD9 controls migration and proliferation of parietal epithelial cells and glomerular disease progression
Hélène Lazareth
,
Carole Henique
,
Olivia Lenoir
,
Victor Puelles
,
Martin Flamant
et al.
Article dans une revue
inserm-02439082
v1
|
|
Posttranslational modifications of sickle hemoglobin in microparticles may promote injury
Pierre-Louis Tharaux
Article dans une revue
hal-03477636
v1
|
|
Murine platelet production is suppressed by S1P release in the hematopoietic niche, not facilitated by blood S1P sensing
Hira Niazi
,
Nesrine Zoghdani
,
Ludovic Couty
,
Alexandre Leuci
,
Anja Nitzsche
et al.
Article dans une revue
inserm-02441591
v1
|
|
Podocytes maintain high basal levels of autophagy independent of mtor signaling
Tillmann Bork
,
Wei Liang
,
Kosuke Yamahara
,
Philipp Lee
,
Zhejia Tian
et al.
Article dans une revue
inserm-02439016
v1
|
|
Selective EGF-Receptor Inhibition in CD4+ T Cells Induces Anergy and Limits Atherosclerosis
Lynda Zeboudj
,
Mikael Maître
,
Léa Guyonnet
,
Ludivine Laurans
,
Jérémie Joffre
et al.
Article dans une revue
hal-02402850
v1
|
|
L’inhibition du récepteur de l’EGF sur les cellules immunitaires réduit l’athérosclérose expérimentale
Lynda Zeboudj
,
Pierre-Louis Tharaux
,
Hafid Ait-Oufella
Article dans une revue
hal-02970129
v1
|
|
Endothelial Epas1 Deficiency Is Sufficient To Promote Parietal Epithelial Cell Activation and FSGS in Experimental Hypertension
Yosu Luque
,
Olivia Lenoir
,
Philippe Bonnin
,
Lise Hardy
,
Anna Chipont
et al.
Article dans une revue
hal-01713482
v1
|
|
Cardiac Metabolic Deregulation Induced by the Tyrosine Kinase Receptor Inhibitor Sunitinib is rescued by Endothelin Receptor Antagonism
Joevin Sourdon
,
Franck Lager
,
Thomas Viel
,
Daniel Balvay
,
Rebecca Moorhouse
et al.
Article dans une revue
hal-01874016
v1
|
|
Cardiac Metabolic Deregulation Induced by the Tyrosine Kinase Receptor Inhibitor Sunitinib is rescued by Endothelin Receptor Antagonism
Joevin Sourdon
,
Franck Lager
,
Thomas Viel
,
Daniel Balvay
,
Rebecca Moorhouse
et al.
Article dans une revue
inserm-02439089
v1
|
|
Hmox1 Deficiency Sensitizes Mice to Peroxynitrite Formation and Diabetic Glomerular Microvascular Injuries
Olivia Lenoir
,
François Gaillard
,
Hélène Lazareth
,
Blaise Robin
,
Pierre-Louis Tharaux
Article dans une revue
hal-03832394
v1
|
|
Genetic and pharmacological inhibition of microRNA-92a maintains podocyte cell cycle quiescence and limits crescentic glomerulonephritis
Carole Henique
,
Guillaume Bollée
,
Xavier Loyer
,
Florian F. Grahammer
,
Neeraj Dhaun
et al.
Article dans une revue
inserm-02439029
v1
|
|
Targeting mTOR Signaling Can Prevent the Progression of FSGS
Stefan Zschiedrich
,
Tillmann Bork
,
Wei Liang
,
Nicola Wanner
,
Kristina Eulenbruch
et al.
Article dans une revue
hal-03253081
v1
|
|
The endothelin B receptor plays a crucial role in the adhesion of neutrophils to the endothelium in sickle cell disease
Bérengère Koehl
,
Pierre Nivoit
,
Wassim El Nemer
,
Olivia Lenoir
,
Patricia Hermand
et al.
Article dans une revue
hal-03832400
v1
|
|
Delayed Healing of Sickle Cell Ulcers Is due to Impaired Angiogenesis and CXCL12 Secretion in Skin Wounds
van Tuan Nguyen
,
Dany Nassar
,
Fréderic Batteux
,
Karine Raymond
,
Pierre-Louis Tharaux
et al.
Article dans une revue
hal-03373337
v1
|
|
Platelet and Erythrocyte Sources of S1P Are Redundant for Vascular Development and Homeostasis, but Both Rendered Essential After Plasma S1P Depletion in Anaphylactic Shock
Salomé L Gazit
,
Boubacar Mariko
,
Patrice Therond
,
Benoit Decouture
,
Yuquan Xiong
et al.
Article dans une revue
inserm-02442039
v1
|
|
A Novel Extrinsic Pathway for the Unfolded Protein Response in the Kidney
Iadh Mami
,
Quentin Tavernier
,
Nicolas Bouvier
,
Rim Aboukamis
,
Geoffroy Desbuissons
et al.
Article dans une revue
hal-01269907
v1
|
|
Efficient second-harmonic imaging of collagen in histological slides using Bessel beam excitation
Nelly Vuillemin
,
Pierre Mahou
,
Delphine Débarre
,
Thierry Gacoin
,
Pierre-Louis Tharaux
et al.
Article dans une revue
hal-01421632
v1
|
|
Endothelial cell and podocyte autophagy synergistically protect from diabetes-induced glomerulosclerosis
Olivia Lenoir
,
Magali Jasiek
,
Carole Henique
,
Lea Guyonnet
,
Bjoern Hartleben
et al.
Article dans une revue
hal-01539607
v1
|
|
Nuclear Factor Erythroid 2-Related Factor 2 Drives Podocyte-Specific Expression of Peroxisome Proliferator-Activated Receptor γ Essential for Resistance to Crescentic GN
Carole Henique
,
Guillaume Bollee
,
Olivia Lenoir
,
Neeraj Dhaun
,
Marine Camus
et al.
Article dans une revue
inserm-03788642
v1
|
|
Lutheran/basal cell adhesion molecule accelerates progression of crescentic glomerulonephritis in mice
Jin Huang
,
Anne Filipe
,
Cécile Rahuel
,
Philippe Bonnin
,
Laurent Mesnard
et al.
Article dans une revue
hal-04764085
v1
|
|
Direct Action of Endothelin-1 on Podocytes Promotes Diabetic Glomerulosclerosis
Olivia Lenoir
,
Marine Milon
,
Anne Virsolvy
,
Carole Henique
,
Alain Schmitt
et al.
Article dans une revue
hal-02542297
v1
|
|
Regulation of the ROS Response Dynamics and Organization to PDGF Motile Stimuli Revealed by Single Nanoparticle Imaging.
Cedric I. Bouzigues
,
Thanh-Liêm Nguyên
,
Rivo Ramodiharilafy
,
Amy Claeson
,
Pierre-Louis Tharaux
et al.
Article dans une revue
hal-01015323
v1
|
|
Multifunctional rare-Earth vanadate nanoparticles: luminescent labels, oxidant sensors, and MRI contrast agents.
Mouna Abdesselem
,
Markus Schoeffel
,
Isabelle Maurin
,
Rivo Ramodiharilafy
,
Gwennhael Autret
et al.
ACS Nano, 2014, 8 (11), pp.11126-37
Article dans une revue
hal-01102505
v1
|
|
Red Blood Cell Sickling During Oxygen Cycles in a Microdroplet Device
Paul Abbyad
,
Remi Dangla
,
Pierre-Louis Tharaux
,
Charles Baroud
,
Antigoni Alexandrou
Article dans une revue
hal-01025970
v1
|
|
Epidermal growth factor receptor promotes glomerular injury and renal failure in rapidly progressive crescentic glomerulonephritis
Guillaume Bollée
,
Martin Flamant
,
Sandra Schordan
,
Cécile Fligny
,
Elisabeth Rumpel
et al.
Article dans une revue
hal-02142778
v1
|
|
Sickling of red blood cells through rapid oxygen exchange in microfluidic drops
Paul Abbyad
,
Pierre-Louis Tharaux
,
Jean-Louis Martin
,
Charles N. Baroud
,
Antigoni Alexandrou
Article dans une revue
istex
hal-00807883
v1
|
|
Glomerular hyperfiltration in adult sickle cell anemia: a frequent hemolysis associated feature.
Jean-Philippe Haymann
,
Katia Stankovic
,
Pierre Levy
,
Virginie Avellino
,
Pierre-Louis Tharaux
et al.
Article dans une revue
hal-00597593
v1
|
|
Single europium-doped nanoparticles measure temporal pattern of reactive oxygen species production inside cells
Didier Casanova
,
Cédric Bouzigues
,
Thanh-Liêm Nguyên
,
Rivo O. Ramodiharilafy
,
Latifa Bouzhir-Sima
et al.
Article dans une revue
hal-00818493
v1
|
|
Second Harmonic Microscopy to Quantify Renal Interstitial Fibrosis and Arterial Remodeling
Mathias Strupler
,
Monica Hernest
,
Cécile Fligny
,
Jean-Louis Martin
,
Pierre-Louis Tharaux
et al.
Article dans une revue
hal-00324221
v1
|
|
Endothelin receptor antagonism prevents hypoxia-induced mortality and morbidity in a mouse model of sickle-cell disease
Nathalie Sabaa
,
Lucia De Franceschi
,
Philippe Bonnin
,
Yves Castier
,
Giorgio Malpeli
et al.
Article dans une revue
hal-02142776
v1
|
|
Second harmonic imaging and scoring of collagen in fibrotic tissues.
Mathias Strupler
,
Ana-Maria Pena
,
Monica Hernest
,
Pierre-Louis Tharaux
,
Jean-Louis Martin
et al.
Article dans une revue
hal-00824058
v1
|
|
Nouvelle approche des fibroses par microscopie multiphotonique avec génération de second harmonique [New approach of fibrosis by multiphoton microscopy with second harmonic generation]
Monica Hernest
,
Ana-Maria Pena
,
Mathias Strupler
,
Emmanuel Beaurepaire
,
Jean-Louis Martin
et al.
Article dans une revue
hal-00100368
v1
|
|
The dual endothelin receptor antagonist bosentan prevents the acute sickle cell-related hypoxic lung and kidney injury in transgenic SAD mice
Nathalie Sabaa
,
Lucia De Franceschi
,
Philippe Bonnin
,
Giorgio Malpeli
,
Stéphane Germain
et al.
Blood, 2006, 108 (11), pp.206A
Article dans une revue
hal-02142743
v1
|
|
Urinary endothelin-1 as a marker of renal damage in sickle cell disease.
Pierre-Louis Tharaux
,
Robert Girot
,
Alain Kanfer
Article dans une revue
inserm-00000115
v1
|
|
Rho Kinase Promotes Alloimmune Responses by Regulating the Proliferation and Structure of T Cells
Pierre-Louis Tharaux
,
Richard Bukoski
,
Paulo Rocha
,
Steven Crowley
,
Phillip Ruiz
et al.
Article dans une revue
inserm-03788598
v1
|
|
Angiotensin II Activates Collagen I Gene Through a Mechanism Involving the MAP/ER Kinase Pathway
Pierre-Louis Tharaux
,
Christos Chatziantoniou
,
Fadi Fakhouri
,
Jean-Claude Dussaule
Article dans une revue
inserm-03788595
v1
|
|
Angiotensin II Activates Collagen Type I Gene in the Renal Vasculature of Transgenic Mice During Inhibition of Nitric Oxide Synthesis
Jean-Jacques Boffa
,
Pierre-Louis Tharaux
,
Sandrine Placier
,
Raymond Ardaillou
,
Jean-Claude Dussaule
et al.
Article dans une revue
inserm-03788594
v1
|
|
Vascular endothelin-1 gene expression and synthesis and effect on renal type I collagen synthesis and nephroangiosclerosis during nitric oxide synthase inhibition in rats.
Pierre-Louis Tharaux
,
Daniel Casellas
Circulation, 1999, 99, pp.2185-91
Article dans une revue
inserm-00000114
v1
|