PT

Pierre-Louis Tharaux

79%
Libre accès
85
Documents
Affiliations actuelles
  • Paris-Centre de Recherche Cardiovasculaire (PARCC (UMR_S 970/ U970))
  • Institut National de la Santé et de la Recherche Médicale (INSERM)
  • UFR Médecine [Santé] - Université Paris Cité (UFR Médecine UPCité)
Contact

Présentation

Domaines de recherche

Sciences du Vivant [q-bio] Médecine humaine et pathologie

Compétences

Biologie vasculaire Auto-immunité maladies rares Néphrologie Hypertension Fibrose Drépanocytose Maladies métaboliques cardiovasculaire diabète drépanocytose Maladies rénales

Publications

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Publications

Image document

VEXAS syndrome is characterized by inflammasome activation and monocyte dysregulation

Olivier Kosmider , Céline Possémé , Marie Templé , Aurélien Corneau , Francesco Carbone et al.
Nature Communications, 2024, 15 (1), pp.910. ⟨10.1038/s41467-024-44811-4⟩
Article dans une revue (article de synthèse) pasteur-04467897 v1

BMP9 is a key player in endothelial identity and its loss is sufficient to induce arteriovenous malformations

Agnes Desroches-Castan , Dzenis Koca , Hequn Liu , Caroline Roelants , Léa Resmini et al.
Cardiovascular Research, 2024, ⟨10.1093/cvr/cvae052⟩
Article dans une revue hal-04543282 v1

Vasorin as an actor of bone turnover?

Caroline Andrique , Anne Laure Bonnet , Julien Dang , Julie Lesieur , A. Michaela Krautzberger et al.
Journal of Cellular Physiology, 2024, 239 (6), pp.e31257. ⟨10.1002/jcp.31257⟩
Article dans une revue hal-04516437 v1

Podocyte Injury in Diabetic Kidney Disease in Mouse Models Involves TRPC6-mediated Calpain Activation Impairing Autophagy

Yann Salemkour , Dilemin Yildiz , Léa Dionet , Kim A.T. Verheijden , Ryuta Saito et al.
Journal of the American Society of Nephrology, 2023, 34 (11), pp.1823-1842. ⟨10.1681/ASN.0000000000000212⟩
Article dans une revue hal-04361228 v1
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More rapid blood interferon α2 decline in fatal versus surviving COVID-19 patients

Candie Joly , Delphine Desjardins , Raphael Porcher , Hélène Péré , Thomas Bruneau et al.
Frontiers in Immunology, 2023, 14, pp.1250214. ⟨10.3389/fimmu.2023.1250214⟩
Article dans une revue hal-04361184 v1

Endothelin blockade prevents the long-term cardiovascular and renal sequelae of acute kidney injury in mice

Alicja Czopek , Rebecca Moorhouse , Peter Gallacher , Dan Pugh , Jessica Ivy et al.
Science Translational Medicine, 2022, 14 (675), ⟨10.1126/scitranslmed.abf5074⟩
Article dans une revue hal-03918227 v1

Should we consider calcimimetics as a therapeutic option for nephrotic syndrome?

Olivia Lenoir , Pierre-Louis Tharaux
Kidney International, 2022, 101 (6), pp.1110-1112. ⟨10.1016/j.kint.2022.04.008⟩
Article dans une revue inserm-03788305 v1

MicroRNAs in kidney injury and disease

Nassim Mahtal , Olivia Lenoir , Claire Tinel , Dany Anglicheau , Pierre-Louis Tharaux
Nature Reviews Nephrology, 2022, 18 (10), pp.643-662. ⟨10.1038/s41581-022-00608-6⟩
Article dans une revue inserm-03787575 v1

Behavioural immune landscapes of inflammation

Georgiana Crainiciuc , Miguel Palomino-Segura , Miguel Molina-Moreno , Jon Sicilia , David Aragones et al.
Nature, 2022, 601 (7893), pp.415-421. ⟨10.1038/s41586-021-04263-y⟩
Article dans une revue hal-04764101 v1

Vasorin Plays a Critical Role in Vascular Smooth Muscle Cells and Arterial Functions.

Loïc Louvet , Gaëlle Lenglet , A. Michaela Krautzberger , Romuald Mentaverri , Frédéric Hague et al.
Journal of Cellular Physiology, 2022, ⟨10.1002/jcp.30838⟩
Article dans une revue hal-03740510 v1
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Effect of interleukin-6 receptor antagonists in critically ill adult patients with COVID-19 pneumonia: two randomised controlled trials of the CORIMUNO-19 Collaborative Group

Olivier Hermine , Xavier Mariette , Raphael Porcher , Matthieu Resche-Rigon , Pierre-Louis Tharaux et al.
European Respiratory Journal, 2022, 60 (2), pp.2102523. ⟨10.1183/13993003.02523-2021⟩
Article dans une revue inserm-03787577 v1
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Tocilizumab plus dexamethasone versus dexamethasone in patients with moderate-to-severe COVID-19 pneumonia: A randomised clinical trial from the CORIMUNO-19 study group

Olivier Hermine , Xavier Mariette , Raphael Porcher , Felix Djossou , Yann Nguyen et al.
EClinicalMedicine, 2022, 46, pp.101362. ⟨10.1016/j.eclinm.2022.101362⟩
Article dans une revue inserm-03787576 v1
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FIBER-ML, an Open-Source Supervised Machine Learning Tool for Quantification of Fibrosis in Tissue Sections

Caterina Facchin , Anais Certain , Thulaciga Yoganathan , Clement Delacroix , Alicia Arevalo Garcia et al.
American Journal of Pathology, 2022, 192 (5), pp.783-793. ⟨10.1016/j.ajpath.2022.01.013⟩
Article dans une revue inserm-03788337 v1
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Severe COVID-19 is associated with hyperactivation of the alternative complement pathway

Jeremy Boussier , Nader Yatim , Armance Marchal , Jérôme Hadjadj , Bruno Charbit et al.
Journal of Allergy and Clinical Immunology, 2022, 149 (2), pp.550-556.e2. ⟨10.1016/j.jaci.2021.11.004⟩
Article dans une revue pasteur-03477606 v1
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ScoMorphoFISH: A deep learning enabled toolbox for single‐cell single‐mRNA quantification and correlative (ultra‐)morphometry

Florian Siegerist , Eleonora Hay , Juan Saydou Dikou , Marion Pollheimer , Anja Büscher et al.
Journal of Cellular and Molecular Medicine, 2022, 26 (12), pp.3513-3526. ⟨10.1111/jcmm.17392⟩
Article dans une revue inserm-03788311 v1
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The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies

Jérémy Manry , Paul Bastard , Adrian Gervais , Tom Le Voyer , Jérémie Rosain et al.
Proceedings of the National Academy of Sciences of the United States of America, 2022, 119 (21), pp.349-363. ⟨10.1073/pnas.2200413119⟩
Article dans une revue hal-03856619 v2
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Differential association between inflammatory cytokines and multiorgan dysfunction in COVID-19 patients with obesity

Marie-Agnès Dragon-Durey , Xiaoyi Chen , Amos Kirilovsky , Nadine Ben Hamouda , Carine El Sissy et al.
PLoS ONE, 2021, 16 (5), pp.e0252026. ⟨10.1371/journal.pone.0252026⟩
Article dans une revue hal-03239731 v1
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Parietal epithelial cell dysfunction in crescentic glomerulonephritis

Milagros N Wong , Pierre-Louis Tharaux , Florian Grahammer , Victor G Puelles
Cell and Tissue Research, 2021, 385 (2), pp.345 - 354. ⟨10.1007/s00441-021-03513-9⟩
Article dans une revue hal-04601799 v1

Effect of anakinra versus usual care in adults in hospital with COVID-19 and mild-to-moderate pneumonia (CORIMUNO-ANA-1): a randomised controlled trial

Pierre-Louis Tharaux , Gilles Pialoux , Arthur Pavot , Xavier Mariette , Olivier Hermine et al.
The Lancet Respiratory Medicine, 2021, 9 (3), pp.295-304. ⟨10.1016/S2213-2600(20)30556-7⟩
Article dans une revue hal-03579180 v1
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Calpastatin prevents Angiotensin II–mediated podocyte injury through maintenance of autophagy

Imane Bensaada , Blaise Robin , Joëlle Perez , Yann Salemkour , Anna Chipont et al.
Kidney International, 2021, 100 (1), pp.90 - 106. ⟨10.1016/j.kint.2021.02.024⟩
Article dans une revue hal-03918903 v1
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Sunitinib-induced cardiac hypertrophy and the endothelin axis

Joevin Sourdon , Caterina Facchin , Anaïs Certain , Thomas Viel , Blaise Robin et al.
Theranostics, 2021, 11, pp.3830 - 3838. ⟨10.7150/thno.49837⟩
Article dans une revue hal-03430957 v1
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Identification of driver genes for critical forms of COVID-19 in a deeply phenotyped young patient cohort

Raphael Carapito , Richard Li , Julie Helms , Christine Carapito , Sharvari Gujja et al.
Science Translational Medicine, 2021, pp.1-59. ⟨10.1126/scitranslmed.abj7521⟩
Article dans une revue hal-03436053 v1

Effect of Tocilizumab vs Usual Care in Adults Hospitalized With COVID-19 and Moderate or Severe Pneumonia

Olivier Hermine , Xavier Mariette , Pierre-Louis Tharaux , Matthieu Resche-Rigon , Raphaël Porcher et al.
JAMA Internal Medicine, 2021, 181 (1), pp.32-40. ⟨10.1001/jamainternmed.2020.6820⟩
Article dans une revue hal-03579175 v1
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3D-printed protected face shields for health care workers in Covid-19 pandemic

Vincent Lemarteleur , Vincent Fouquet , Stéphane Le Goff , Laurent Tapie , Pascal Morenton et al.
American Journal of Infection Control, 2021, 49 (3), pp.389-391. ⟨10.1016/j.ajic.2020.08.005⟩
Article dans une revue hal-03249487 v1
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Endothelial S1P 1 Signaling Counteracts Infarct Expansion in Ischemic Stroke

Anja Nitzsche , Marine Poittevin , Ammar Benarab , Philippe Bonnin , Giuseppe Faraco et al.
Circulation Research, 2021, 128 (3), pp.363-382. ⟨10.1161/CIRCRESAHA.120.316711⟩
Article dans une revue hal-03886183 v1
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Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths

Paul Bastard , Adrian Gervais , Tom Le Voyer , Jeremie Rosain , Quentin Philippot et al.
Science Immunology, 2021, 6 (62), pp.eabl4340. ⟨10.1126/sciimmunol.abl4340⟩
Article dans une revue hal-03358792 v1
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The proteome of neutrophils in sickle cell disease reveals an unexpected activation of interferon alpha signaling pathway

Patricia Hermand , Slim Azouzi , Emilie-Fleur Gautier , François Guillonneau , Vincent Bondet et al.
Haematologica, 2020, pp.haematol.2019.238295. ⟨10.3324/haematol.2019.238295⟩
Article dans une revue pasteur-02505633 v1

Deletion of the myeloid endothelin-B receptor confers long-term protection from angiotensin II-mediated kidney, eye and vessel injury

Léa Guyonnet , Alicja Czopek , Tariq Farrah , Véronique Baudrie , Philippe Bonnin et al.
Kidney International, 2020, 98 (5), pp.1193-1209. ⟨10.1016/j.kint.2020.05.042⟩
Article dans une revue hal-03832377 v1
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Deletion of the myeloid endothelin-B receptor confers long-term protection from angiotensin II-mediated kidney, eye and vessel injury

Léa Guyonnet , Alicja Czopek , Tariq E Farrah , Véronique Baudrie , Philippe Bonnin et al.
Kidney International, 2020, 98 (5), pp.1193-1209. ⟨10.1016/j.kint.2020.05.042⟩
Article dans une revue hal-03268543 v1
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Histamine provides an original vista on cardiorenal syndrome

Pierre-Louis Tharaux
Proceedings of the National Academy of Sciences of the United States of America, 2020, 117 (11), pp.5550-5552. ⟨10.1073/pnas.2001336117⟩
Article dans une revue hal-04764092 v1

Podocytes maintain high basal levels of autophagy independent of mtor signaling

Tillmann Bork , Wei Liang , Kosuke Yamahara , Philipp Lee , Zhejia Tian et al.
Autophagy, 2020, 16 (11), pp.1932-1948. ⟨10.1080/15548627.2019.1705007⟩
Article dans une revue hal-03832381 v1
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Metabolomic Profiling of Plasma and Erythrocytes in Sickle Mice Points to Altered Nociceptive Pathways

Klétigui Casimir Dembélé , Thomas Mintz , Charlotte Veyrat-Durebex , Floris Chabrun , Stéphanie Chupin et al.
Cells, 2020, 9 (6), pp.1334. ⟨10.3390/cells9061334⟩
Article dans une revue hal-02974118 v1
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Rôle pathogénique de l’expression anormale de la tétraspanine CD9 par les cellules épithéliales pariétales dans les glomérulopathies extracapillaires

Hélène Lazareth , Olivia Lenoir , Carole Hénique , Cédric Bouzigues , Claude Boucheix et al.
Médecine/Sciences, 2020, 36 (10), pp.852-855. ⟨10.1051/medsci/2020154⟩
Article dans une revue hal-02960790 v1
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Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients

Jérôme Hadjadj , Nader Yatim , Laura Barnabei , Aurélien Corneau , Jeremy Boussier et al.
Science, 2020, Online ahead of print, pp.eabc6027. ⟨10.1126/science.abc6027⟩
Article dans une revue pasteur-02900830 v1
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A novel role for myeloid endothelin-B receptors in hypertension

Alicja Czopek , Rebecca Moorhouse , Léa Guyonnet , Tariq Farrah , Olivia Lenoir et al.
European Heart Journal, 2019, 40 (9), pp.768-784. ⟨10.1093/eurheartj/ehy881⟩
Article dans une revue inserm-02439065 v1
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Local miscommunications between glomerular cells as potential therapeutic targets for crescentic glomerulonephritides

Carole Hénique , Olivia Lenoir , Alexandre Karras , Pierre-Louis Tharaux
Néphrologie & Thérapeutique, 2019, 15, pp.S1 - S5. ⟨10.1016/j.nephro.2019.03.006⟩
Article dans une revue hal-03485068 v1
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L’hypertension artérielle maligne , un futur prometteur

Romain Boulestreau , Antoine Cremer , Aurelien Lorthioir , Sébastien Rubin , Pierre-Louis Tharaux et al.
La Presse Médicale, 2019, 48 (12), pp.1439-1444. ⟨10.1016/j.lpm.2019.07.007⟩
Article dans une revue hal-03117380 v1
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A novel role for myeloid endothelin-B receptors in hypertension

Alicja Czopek , Rebecca Moorhouse , Léa Guyonnet , Tariq Farrah , Olivia Lenoir et al.
European Heart Journal, 2019, 40 (9), pp.768 - 784. ⟨10.1093/eurheartj/ehy881⟩
Article dans une revue hal-03918917 v1
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The tetraspanin CD9 controls migration and proliferation of parietal epithelial cells and glomerular disease progression

Hélène Lazareth , Carole Henique , Olivia Lenoir , Victor Puelles , Martin Flamant et al.
Nature Communications, 2019, 10 (1), pp.3303. ⟨10.1038/s41467-019-11013-2⟩
Article dans une revue inserm-02439082 v1
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Posttranslational modifications of sickle hemoglobin in microparticles may promote injury

Pierre-Louis Tharaux
Kidney International, 2019, 95, pp.1289 - 1291. ⟨10.1016/j.kint.2019.02.023⟩
Article dans une revue hal-03477636 v1
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Murine platelet production is suppressed by S1P release in the hematopoietic niche, not facilitated by blood S1P sensing

Hira Niazi , Nesrine Zoghdani , Ludovic Couty , Alexandre Leuci , Anja Nitzsche et al.
Blood Advances, 2019, 3 (11), pp.1702-1713. ⟨10.1182/bloodadvances.2019031948⟩
Article dans une revue inserm-02441591 v1
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Podocytes maintain high basal levels of autophagy independent of mtor signaling

Tillmann Bork , Wei Liang , Kosuke Yamahara , Philipp Lee , Zhejia Tian et al.
Autophagy, 2019, 23, pp.1-17. ⟨10.1080/15548627.2019.1705007⟩
Article dans une revue inserm-02439016 v1
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Selective EGF-Receptor Inhibition in CD4+ T Cells Induces Anergy and Limits Atherosclerosis

Lynda Zeboudj , Mikael Maître , Léa Guyonnet , Ludivine Laurans , Jérémie Joffre et al.
Journal of the American College of Cardiology, 2018, 71 (2), pp.160-172. ⟨10.1016/j.jacc.2017.10.084⟩
Article dans une revue hal-02402850 v1
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L’inhibition du récepteur de l’EGF sur les cellules immunitaires réduit l’athérosclérose expérimentale

Lynda Zeboudj , Pierre-Louis Tharaux , Hafid Ait-Oufella
Médecine/Sciences, 2018, 34 (6-7), pp.501-504. ⟨10.1051/medsci/20183406002⟩
Article dans une revue hal-02970129 v1
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Endothelial Epas1 Deficiency Is Sufficient To Promote Parietal Epithelial Cell Activation and FSGS in Experimental Hypertension

Yosu Luque , Olivia Lenoir , Philippe Bonnin , Lise Hardy , Anna Chipont et al.
Journal of the American Society of Nephrology, 2017, 28 (12), pp.3563-3578. ⟨10.1681/ASN.2016090960⟩
Article dans une revue hal-01713482 v1
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Cardiac Metabolic Deregulation Induced by the Tyrosine Kinase Receptor Inhibitor Sunitinib is rescued by Endothelin Receptor Antagonism

Joevin Sourdon , Franck Lager , Thomas Viel , Daniel Balvay , Rebecca Moorhouse et al.
Theranostics, 2017, 7 (11), pp.2757-2774. ⟨10.7150/thno.19551⟩
Article dans une revue hal-01874016 v1
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Cardiac Metabolic Deregulation Induced by the Tyrosine Kinase Receptor Inhibitor Sunitinib is rescued by Endothelin Receptor Antagonism

Joevin Sourdon , Franck Lager , Thomas Viel , Daniel Balvay , Rebecca Moorhouse et al.
Theranostics, 2017, 7 (11), pp.2757-2774. ⟨10.7150/thno.19551⟩
Article dans une revue inserm-02439089 v1
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Hmox1 Deficiency Sensitizes Mice to Peroxynitrite Formation and Diabetic Glomerular Microvascular Injuries

Olivia Lenoir , François Gaillard , Hélène Lazareth , Blaise Robin , Pierre-Louis Tharaux
Journal of diabetes research, 2017, 2017, pp.1-7. ⟨10.1155/2017/9603924⟩
Article dans une revue hal-03832394 v1
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Genetic and pharmacological inhibition of microRNA-92a maintains podocyte cell cycle quiescence and limits crescentic glomerulonephritis

Carole Henique , Guillaume Bollée , Xavier Loyer , Florian F. Grahammer , Neeraj Dhaun et al.
Nature Communications, 2017, 8 (1), pp.1829. ⟨10.1038/s41467-017-01885-7⟩
Article dans une revue inserm-02439029 v1
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Targeting mTOR Signaling Can Prevent the Progression of FSGS

Stefan Zschiedrich , Tillmann Bork , Wei Liang , Nicola Wanner , Kristina Eulenbruch et al.
Journal of the American Society of Nephrology, 2017, 28 (7), pp.2144 - 2157. ⟨10.1681/asn.2016050519⟩
Article dans une revue hal-03253081 v1
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The endothelin B receptor plays a crucial role in the adhesion of neutrophils to the endothelium in sickle cell disease

Bérengère Koehl , Pierre Nivoit , Wassim El Nemer , Olivia Lenoir , Patricia Hermand et al.
Haematologica, 2017, 102 (7), pp.1161-1172. ⟨10.3324/haematol.2016.156869⟩
Article dans une revue hal-03832400 v1

Delayed Healing of Sickle Cell Ulcers Is due to Impaired Angiogenesis and CXCL12 Secretion in Skin Wounds

van Tuan Nguyen , Dany Nassar , Fréderic Batteux , Karine Raymond , Pierre-Louis Tharaux et al.
Journal of Investigative Dermatology, 2016, 136 (2), pp.497-506. ⟨10.1016/j.jid.2015.11.005⟩
Article dans une revue hal-03373337 v1

Platelet and Erythrocyte Sources of S1P Are Redundant for Vascular Development and Homeostasis, but Both Rendered Essential After Plasma S1P Depletion in Anaphylactic Shock

Salomé L Gazit , Boubacar Mariko , Patrice Therond , Benoit Decouture , Yuquan Xiong et al.
Circulation Research, 2016, 119 (8), pp.e110-26. ⟨10.1161/CIRCRESAHA.116.308929⟩
Article dans une revue inserm-02442039 v1

A Novel Extrinsic Pathway for the Unfolded Protein Response in the Kidney

Iadh Mami , Quentin Tavernier , Nicolas Bouvier , Rim Aboukamis , Geoffroy Desbuissons et al.
Journal of the American Society of Nephrology, 2016, 27 (9), pp.2670-83. ⟨10.1681/ASN.2015060703⟩
Article dans une revue hal-01269907 v1
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Efficient second-harmonic imaging of collagen in histological slides using Bessel beam excitation

Nelly Vuillemin , Pierre Mahou , Delphine Débarre , Thierry Gacoin , Pierre-Louis Tharaux et al.
Scientific Reports, 2016, 6 (29863 (2016)), ⟨10.1038/srep29863⟩
Article dans une revue hal-01421632 v1

Endothelial cell and podocyte autophagy synergistically protect from diabetes-induced glomerulosclerosis

Olivia Lenoir , Magali Jasiek , Carole Henique , Lea Guyonnet , Bjoern Hartleben et al.
Autophagy, 2015, 11 (7), pp.1130-1145. ⟨10.1080/15548627.2015.1049799⟩
Article dans une revue hal-01539607 v1
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Nuclear Factor Erythroid 2-Related Factor 2 Drives Podocyte-Specific Expression of Peroxisome Proliferator-Activated Receptor γ Essential for Resistance to Crescentic GN

Carole Henique , Guillaume Bollee , Olivia Lenoir , Neeraj Dhaun , Marine Camus et al.
Journal of the American Society of Nephrology, 2015, 27 (1), pp.172-188. ⟨10.1681/ASN.2014111080⟩
Article dans une revue inserm-03788642 v1
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Lutheran/basal cell adhesion molecule accelerates progression of crescentic glomerulonephritis in mice

Jin Huang , Anne Filipe , Cécile Rahuel , Philippe Bonnin , Laurent Mesnard et al.
Kidney International, 2014, 85 (5), ⟨10.1038/ki.2013.522⟩
Article dans une revue hal-04764085 v1
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Direct Action of Endothelin-1 on Podocytes Promotes Diabetic Glomerulosclerosis

Olivia Lenoir , Marine Milon , Anne Virsolvy , Carole Henique , Alain Schmitt et al.
Journal of the American Society of Nephrology, 2014, 25 (5), pp.1050-1062. ⟨10.1681/ASN.2013020195⟩
Article dans une revue hal-02542297 v1

Regulation of the ROS Response Dynamics and Organization to PDGF Motile Stimuli Revealed by Single Nanoparticle Imaging.

Cedric I. Bouzigues , Thanh-Liêm Nguyên , Rivo Ramodiharilafy , Amy Claeson , Pierre-Louis Tharaux et al.
Chemistry and Biology, 2014, 21 (5), pp.647-56. ⟨10.1016/j.chembiol.2014.02.020⟩
Article dans une revue hal-01015323 v1

Multifunctional rare-Earth vanadate nanoparticles: luminescent labels, oxidant sensors, and MRI contrast agents.

Mouna Abdesselem , Markus Schoeffel , Isabelle Maurin , Rivo Ramodiharilafy , Gwennhael Autret et al.
ACS Nano, 2014, 8 (11), pp.11126-37
Article dans une revue hal-01102505 v1

Red Blood Cell Sickling During Oxygen Cycles in a Microdroplet Device

Paul Abbyad , Remi Dangla , Pierre-Louis Tharaux , Charles Baroud , Antigoni Alexandrou
Biophysical Journal, 2012, 102 (3), pp.29A-29A. ⟨10.1016/j.bpj.2011.11.184⟩
Article dans une revue hal-01025970 v1

Epidermal growth factor receptor promotes glomerular injury and renal failure in rapidly progressive crescentic glomerulonephritis

Guillaume Bollée , Martin Flamant , Sandra Schordan , Cécile Fligny , Elisabeth Rumpel et al.
Nature Medicine, 2011, 17 (10), pp.1242--1250. ⟨10.1038/nm.2491⟩
Article dans une revue hal-02142778 v1

Sickling of red blood cells through rapid oxygen exchange in microfluidic drops

Paul Abbyad , Pierre-Louis Tharaux , Jean-Louis Martin , Charles N. Baroud , Antigoni Alexandrou
Lab on a Chip, 2010, 10 (19), pp.2505. ⟨10.1039/c004390g⟩
Article dans une revue istex hal-00807883 v1

Glomerular hyperfiltration in adult sickle cell anemia: a frequent hemolysis associated feature.

Jean-Philippe Haymann , Katia Stankovic , Pierre Levy , Virginie Avellino , Pierre-Louis Tharaux et al.
Clinical Journal of the American Society of Nephrology, 2010, 5 (5), pp.756-61. ⟨10.2215/CJN.08511109⟩
Article dans une revue hal-00597593 v1

Single europium-doped nanoparticles measure temporal pattern of reactive oxygen species production inside cells

Didier Casanova , Cédric Bouzigues , Thanh-Liêm Nguyên , Rivo O. Ramodiharilafy , Latifa Bouzhir-Sima et al.
Nature Nanotechnology, 2009, 4 (9), pp.581. ⟨10.1038/nnano.2009.200⟩
Article dans une revue hal-00818493 v1

Second Harmonic Microscopy to Quantify Renal Interstitial Fibrosis and Arterial Remodeling

Mathias Strupler , Monica Hernest , Cécile Fligny , Jean-Louis Martin , Pierre-Louis Tharaux et al.
Journal of Biomedical Optics, 2008, 13 (5), pp.054041. ⟨10.1117/1.2981830⟩
Article dans une revue hal-00324221 v1

Endothelin receptor antagonism prevents hypoxia-induced mortality and morbidity in a mouse model of sickle-cell disease

Nathalie Sabaa , Lucia De Franceschi , Philippe Bonnin , Yves Castier , Giorgio Malpeli et al.
Journal of Clinical Investigation, 2008, 118 (5), pp.1924--1933. ⟨10.1172/JCI33308⟩
Article dans une revue hal-02142776 v1
Image document

Second harmonic imaging and scoring of collagen in fibrotic tissues.

Mathias Strupler , Ana-Maria Pena , Monica Hernest , Pierre-Louis Tharaux , Jean-Louis Martin et al.
Optics Express, 2007, 15 (7), pp.4054-4065. ⟨10.1364/OE.15.004054⟩
Article dans une revue hal-00824058 v1
Image document

Nouvelle approche des fibroses par microscopie multiphotonique avec génération de second harmonique [New approach of fibrosis by multiphoton microscopy with second harmonic generation]

Monica Hernest , Ana-Maria Pena , Mathias Strupler , Emmanuel Beaurepaire , Jean-Louis Martin et al.
Médecine/Sciences, 2006, 22 (10), pp.820-821. ⟨10.1051/medsci/20062210820⟩
Article dans une revue hal-00100368 v1

The dual endothelin receptor antagonist bosentan prevents the acute sickle cell-related hypoxic lung and kidney injury in transgenic SAD mice

Nathalie Sabaa , Lucia De Franceschi , Philippe Bonnin , Giorgio Malpeli , Stéphane Germain et al.
Blood, 2006, 108 (11), pp.206A
Article dans une revue hal-02142743 v1

Urinary endothelin-1 as a marker of renal damage in sickle cell disease.

Pierre-Louis Tharaux , Robert Girot , Alain Kanfer
Nephrology Dialysis Transplantation, 2005, 20, pp.2408-13. ⟨10.1093/ndt/gfi111⟩
Article dans une revue inserm-00000115 v1
Image document

Rho Kinase Promotes Alloimmune Responses by Regulating the Proliferation and Structure of T Cells

Pierre-Louis Tharaux , Richard Bukoski , Paulo Rocha , Steven Crowley , Phillip Ruiz et al.
Journal of Immunology, 2003, 171 (1), pp.96-105. ⟨10.4049/jimmunol.171.1.96⟩
Article dans une revue inserm-03788598 v1
Image document

Angiotensin II Activates Collagen I Gene Through a Mechanism Involving the MAP/ER Kinase Pathway

Pierre-Louis Tharaux , Christos Chatziantoniou , Fadi Fakhouri , Jean-Claude Dussaule
Hypertension, 2000, 36 (3), pp.330-336. ⟨10.1161/01.hyp.36.3.330⟩
Article dans une revue inserm-03788595 v1
Image document

Angiotensin II Activates Collagen Type I Gene in the Renal Vasculature of Transgenic Mice During Inhibition of Nitric Oxide Synthesis

Jean-Jacques Boffa , Pierre-Louis Tharaux , Sandrine Placier , Raymond Ardaillou , Jean-Claude Dussaule et al.
Circulation, 1999, 100 (18), pp.1901-1908. ⟨10.1161/01.cir.100.18.1901⟩
Article dans une revue inserm-03788594 v1

Vascular endothelin-1 gene expression and synthesis and effect on renal type I collagen synthesis and nephroangiosclerosis during nitric oxide synthase inhibition in rats.

Pierre-Louis Tharaux , Daniel Casellas
Circulation, 1999, 99, pp.2185-91
Article dans une revue inserm-00000114 v1

A novel mouse model of hypertensive emergency with microvascular disease implicating the VEGFA/sFlt-1 balance

Thibaut d'Izarny-Gargas , Lea Guyonnet , Sarah Azancot , Léa Resmini , Emilie Vessières et al.
ERCSG, 2024, Leigh, United Kingdom
Communication dans un congrès hal-04737060 v1

A novel mouse model of hypertensive emergency with microvascular disease implicating the VEGFA/sFlt-1 balance

Thibaut d'Izarny-Gargas , Lea Guyonnet , Sarah Azancot , Léa Resmini , Emilie Vessières et al.
SFNDT, 2024, Bordeaux, France
Communication dans un congrès hal-04737073 v1

Sickling of red blood cells in microfluidic droplets

Paul Abbyad , Charles N. Baroud , Jean-Louis Martin , Pierre-Louis Tharaux , Antigoni Alexandrou
239th ACS National Meeting, Mar 2010, San Francisco, United States
Communication dans un congrès hal-01025985 v1

Red Blood Cell Sickling in Microfluidic droplets

Paul Abbyad , Charles N. Baroud , Pierre-Louis Tharaux , Antigoni Alexandrou
13th International Conference on Miniaturized Systems in Chemistry and Life Sciences (μTAS 2009), Nov 2009, Jeju, South Korea
Communication dans un congrès hal-01053382 v1

Second harmonic microscopy to quantify fibrotic pathologies and arterial remodeling

Mathias Strupler , Monica Hernest , Jean-Louis Martin , Pierre-Louis Tharaux , Emmanuel Beaurepaire et al.
EOS TOPICAL MEETING ON PHOTONIC DEVICES, Mar 2008, Utrecht, Netherlands
Communication dans un congrès hal-00324286 v1

Nonlinear microscopy using Second Harmonic Generation from myosin filaments and fibrillar collagens

Ana-Maria Pena , Mathias Strupler , Thierry Boulesteix , Aude Fabre , Monica Hernest et al.
European Muscle Conference 2006, 2006, Heidelberg, Germany
Communication dans un congrès hal-00100371 v1

SHG microscopy. Quantitative scoring of kidney collagen fibrosis. (prix du meilleur poster)

Mathias Strupler , Monica Hernest , Ana-Maria Pena , Jean-Louis Martin , Emmanuel Beaurepaire et al.
Ecole thématique MiFoBio, 2006, La Grande Motte, France
Communication dans un congrès hal-00100388 v1

ROS Detection and Quantification with Lanthanide-Based Nanosensors

Mouna Abdesselem , Thierry Gacoin , Jean-Pierre Boilot , Pierre-Louis Tharaux , Antigoni Alexandrou et al.
59th Annual Meeting of the Biophysical-Society, Feb 2015, Baltimore, United States. Biophysical Journal, 108 (2), pp.483a, 2015, ⟨10.1016/j.bpj.2014.11.2640⟩
Poster de conférence hal-01237532 v1