Luc ZIMMER

Professeur des Universités-Praticien Hospitalier (Neuropharmacologie)
138
Documents
Affiliations actuelles
  • Centre de recherche en neurosciences de Lyon - Lyon Neuroscience Research Center (CRNL)
  • Centre d'Etude et de Recherche Multimodal Et Pluridisciplinaire en imagerie du vivant (CERMEP - imagerie du vivant)
  • Institut National des Sciences et Techniques Nucléaires (INSTN)
  • Radiopharmaceutical and Neurochemical Biomarkers (CRNL-BIORAN)
  • Hospices Civils de Lyon (HCL)

Publications

Publications

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Serotonin 5-HT1A receptor biased agonists: The challenge of translating an innovative neuropharmacological concept into therapeutics

Luc Zimmer , Adrian Newman-Tancredi
Neuropharmacology, 2025, 265, pp.110267. ⟨10.1016/j.neuropharm.2024.110267⟩
Article dans une revue hal-04914119 v1

Pharmacodynamic, pharmacokinetic and rat brain receptor occupancy profile of NLX-112, a highly selective 5-HT1A receptor biased agonist

Ronan Depoortère , Andrew Mccreary , Benjamin Vidal , Mark Varney , Luc Zimmer et al.
Naunyn-Schmiedeberg's Archives of Pharmacology, 2024, ⟨10.1007/s00210-024-03323-0⟩
Article dans une revue hal-04763126 v1
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WAY-208466, a 5-HT6 receptor agonist, increases food motivation in primates: A behavioural and PET imaging study opening perspectives in eating disorders

Mathilde Pitoy , Julie Maulavé , Lisa Gauthier , Justine Debatisse , Nicolas Costes et al.
Neuroscience Applied, 2024, 3, pp.104086. ⟨10.1016/j.nsa.2024.104086⟩
Article dans une revue hal-04811333 v1
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NMDA antagonist agents for the treatment of symptoms in autism spectrum disorder: a systematic review and meta-analysis

Marie-Lou Dessus-Gilbert , Mikail Nourredine , Luc Zimmer , Benjamin Rolland , Marie-Maude Geoffray et al.
Frontiers in Pharmacology, 2024, 15, pp.1395867. ⟨10.3389/fphar.2024.1395867⟩
Article dans une revue (article de synthèse) hal-04932440 v1
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Toward Multidisciplinary Tools for Complex Clinical Psychopharmacology Cases: A Qualitative Study with French Healthcare Professionals

Matthieu Lebrat , Rachel Megard , Anne-Cecile Gallo Blandin , Nicolas Franck , Luc Zimmer
Journal of Multidisciplinary Healthcare, 2024, Volume 17, pp.6017-6030. ⟨10.2147/JMDH.S481398⟩
Article dans une revue hal-04842732 v1
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A revisited version of the disputatio for pharmacological training: An educational study

Louise Carton , Perle Totoson , Edouard-Jules Laforgue , Jean-Marc Pelerin , Thomas Portier-Feunteun et al.
Therapies, 2024, 79 (4), pp.435-441. ⟨10.1016/j.therap.2023.10.016⟩
Article dans une revue hal-04805817 v1
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SB-258585 reduces food motivation while blocking 5-HT$_6$ receptors in the non-human primate striatum

Mathilde Pitoy , Lisa Gauthier , Justine Debatisse , Julie Maulavé , Elise Météreau et al.
Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2024, 131, pp.110970. ⟨10.1016/j.pnpbp.2024.110970⟩
Article dans une revue hal-04566627 v1
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[18F]RS-127445 radiosynthesis and evaluation as a 5-HT2B receptor PET radiotracer in rat brain

Violette Richin , Caroline Bouillot , Sandrine Bouvard , Pierre Courault , Sophie Lancelot et al.
Bioorganic and Medicinal Chemistry Letters, 2024, 112, pp.129933. ⟨10.1016/j.bmcl.2024.129933⟩
Article dans une revue hal-04794525 v1
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Preclinical investigation of the effect of stress on the binding of [18F]F13640, a 5-HT1A radiopharmaceutical

Pierre Courault , Sandrine Bouvard , Caroline Bouillot , Luc Zimmer , Sophie Lancelot
Nuclear Medicine and Biology, 2024, 138-139, pp.108942. ⟨10.1016/j.nucmedbio.2024.108942⟩
Article dans une revue hal-04794527 v1
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Identification of factors associated with hospitalization in an outpatient population with mental health conditions: a case–control study

Matthieu Lebrat , Rachel Megard , Cédric Dananché , Luc Zimmer , Julien Plasse et al.
Frontiers in Psychiatry, 2024, 15, pp.1341160. ⟨10.3389/fpsyt.2024.1341160⟩
Article dans une revue hal-04824949 v1
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Characterization of IMIC, an implantable needle-shaped positron sensitive monolithic active pixel sensor for preclinical molecular neuroimaging

S El Ketara , F Agnese , L Ammour , S Bouvard , O Clausse et al.
Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 2024, 1064, pp.169456. ⟨10.1016/j.nima.2024.169456⟩
Article dans une revue hal-04592637 v1
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Pharmacodynamic, pharmacokinetic and rat brain receptor occupancy profile of NLX-112, a highly selective 5-HT 1A receptor biased agonist

Ronan Y Depoortère , Andrew C Mccreary , Benjamin Vidal , Mark A Varney , Luc Zimmer et al.
Naunyn-Schmiedeberg's Archives of Pharmacology, 2024, 398 (1), pp.991-1002. ⟨10.1007/s00210-024-03323-0⟩
Article dans une revue hal-04932477 v1
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Not so paradoxical … Neurobiology of attention deficit–hyperactivity disorder (ADHD) and therapeutic mode of action of psychostimulants

Benjamin Rolland , Luc Zimmer , Hugo Prunier , Guillaume Sescousse
Annales Médico-Psychologiques, Revue Psychiatrique, 2024, ⟨10.1016/j.amp.2024.09.002⟩
Article dans une revue hal-04932443 v1
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Perspectives on obesity imaging: [18F]2FNQ1P a specific 5-HT6 brain PET radiotracer

Pierre Courault , Sandrine Bouvard , Caroline Bouillot , Radu Bolbos , Waël Zeinyeh et al.
International Journal of Obesity, 2024, ⟨10.1038/s41366-024-01644-x⟩
Article dans une revue hal-04793046 v1
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Toward Functional PET Imaging of the Spinal Cord

Pierre Courault , Luc Zimmer , Sophie Lancelot
Seminars in Nuclear Medicine, 2024, ⟨10.1053/j.semnuclmed.2024.07.002⟩
Article dans une revue hal-04794514 v1
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[18F]F13640: a selective agonist PET radiopharmaceutical for imaging functional 5-HT1A receptors in humans

Pierre Courault , Sophie Lancelot , Nicolas Costes , Matthieu Colom , Didier Le Bars et al.
European Journal of Nuclear Medicine and Molecular Imaging, 2023, 50 (6), pp.1651-1664. ⟨10.1007/s00259-022-06103-1⟩
Article dans une revue hal-04528816 v1
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A consensus protocol for functional connectivity analysis in the rat brain

Joanes Grandjean , Gabriel Desrosiers-Gregoire , Cynthia Anckaerts , Diego Angeles-Valdez , Fadi Ayad et al.
Nature Neuroscience, 2023, 26 (4), pp.673-681. ⟨10.1038/s41593-023-01286-8⟩
Article dans une revue hal-04268925 v1
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Multimodal imaging study of the 5-HT1A receptor biased agonist, NLX-112, in a model of L-DOPA-induced dyskinesia

Sarah Chaib , Benjamin Vidal , Caroline Bouillot , Ronan Depoortere , Adrian Newman-Tancredi et al.
Neuroimage-Clinical, 2023, 39, pp.103497. ⟨10.1016/j.nicl.2023.103497⟩
Article dans une revue hal-04763124 v1
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Single subanesthetic dose of ketamine produces delayed impact on brain [18F]FDG PET imaging and metabolic connectivity in rats

Sarah Chaib , Caroline Bouillot , Sandrine Bouvard , Benjamin Vidal , Luc Zimmer et al.
Frontiers in Neuroscience, 2023, 17, pp.1213941. ⟨10.3389/fnins.2023.1213941⟩
Article dans une revue hal-04528862 v1
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3D-printed dual holder system for simultaneous rat PET scanning: design and influence on quantification

Caroline Bouillot , Sébastien Daligault , Radu Bolbos , Nicolas Costes , Luc Zimmer
EJNMMI Research, 2023, 13 (1), pp.80. ⟨10.1186/s13550-023-01027-9⟩
Article dans une revue hal-04930517 v1
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Anti-CD20 therapies in multiple sclerosis: From pathology to the clinic

Jérôme de Sèze , Elisabeth Maillart , Antoine Gueguen , David‐axel Laplaud , Laure Michel et al.
Frontiers in Immunology, 2023, 14, pp.1004795. ⟨10.3389/fimmu.2023.1004795⟩
Article dans une revue (article de synthèse) hal-04086889 v1

Positron Emission Tomography for the Discovery of New Drugs in Psychiatry

Luc Zimmer
ACS Chemical Neuroscience, 2023, 14 (4), pp.524-526. ⟨10.1021/acschemneuro.3c00036⟩
Article dans une revue hal-04528842 v1
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Recent applications of positron emission tomographic (PET) imaging in psychiatric drug discovery

Luc Zimmer
Expert Opinion on Drug Discovery, 2023, 19 (2), pp.161-172. ⟨10.1080/17460441.2023.2278635⟩
Article dans une revue (article de synthèse) hal-04815147 v1

Author Correction: A consensus protocol for functional connectivity analysis in the rat brain

Joanes Grandjean , Gabriel Desrosiers-Gregoire , Cynthia Anckaerts , Diego Angeles-Valdez , Fadi Ayad et al.
Nature Neuroscience, 2023, 26 (6), pp.1127-1128. ⟨10.1038/s41593-023-01328-1⟩
Article dans une revue inserm-04917769 v1

Pharmaco-fUS in cognitive impairment: Lessons from a preclinical model

Benjamin Vidal , Mickaël Pereira , Marco Valdebenito , Louis Vidal , Franck Mouthon et al.
Journal of Psychopharmacology, 2022, 36 (11), pp.1273-1279. ⟨10.1177/02698811221128963⟩
Article dans une revue hal-04763123 v1
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PET metabolic imaging of time-dependent reorganization of olfactory cued fear memory networks in rats

Anne-Marie Mouly , Caroline Bouillot , Nicolas Costes , Luc Zimmer , Nadine Ravel et al.
Cerebral Cortex, 2022, 32 (13), pp.2717-2728. ⟨10.1093/cercor/bhab376⟩
Article dans une revue hal-03772913 v1

Impaired Local and Long-Range Brain Connectivity and Visual Response in a Genetic Rat Model of Hyperactivity Revealed by Functional Ultrasound

Marine Droguerre , Benjamin Vidal , Marco Valdebenito , Franck Mouthon , Luc Zimmer et al.
Frontiers in Neuroscience, 2022, 16, ⟨10.3389/fnins.2022.865140⟩
Article dans une revue hal-04763120 v1
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Comparative diagnosis interest of NfL and pNfH in CSF and plasma in a context of FTD–ALS spectrum

Jean Escal , Anthony Fourier , Maïté Formaglio , Luc Zimmer , Emilien Bernard et al.
Journal of Neurology, 2022, 269 (3), pp.1522-1529. ⟨10.1007/s00415-021-10714-3⟩
Article dans une revue hal-04796041 v1
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[18F]F13640, a 5-HT1A Receptor Radiopharmaceutical Sensitive to Brain Serotonin Fluctuations

Matthieu Colom , Benjamin Vidal , Sylvain Fieux , Jérôme Redouté , Nicolas Costes et al.
Frontiers in Neuroscience, 2021, 15, pp.622423. ⟨10.3389/fnins.2021.622423⟩
Article dans une revue hal-03407570 v1
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Innovative approaches in CNS drug discovery

Mathieu Charvériat , Vincent Lafon , Franck Mouthon , Luc Zimmer
Alternative and Complementary Therapies, 2021, 76 (2), pp.101-109. ⟨10.1016/j.therap.2020.12.006⟩
Article dans une revue hal-03160773 v1
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Cluster headache: state of the art of pharmacological treatments and therapeutic perspectives

Pierre Courault , Genevieve Demarquay , Luc Zimmer , Sophie Lancelot
Fundamental & Clinical Pharmacology, 2021, Themed series on Neuropharmacology, 35 (3), pp.595-619. ⟨10.1111/fcp.12636⟩
Article dans une revue hal-04799225 v1
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Different alterations of agonist and antagonist binding to 5-HT1A receptor in a rat model of Parkinson's disease and levodopa-induced dyskinesia : a microPET study

Benjamin Vidal , Élise Levigoureux , Sarah Chaib , Caroline Bouillot , Thierry Billard et al.
Journal of Parkinson's disease, 2021, 11 (3), pp.1257-1269. ⟨10.3233/JPD-212580⟩
Article dans une revue hal-03407557 v1
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Clinical research in psychopharmacology, the current situation and its perspectives. A conversation with Pierre-Michel Llorca

Pierre-Michel Llorca , Luc Zimmer
Thérapie, 2021, 76 (2), pp.67-70. ⟨10.1016/j.therap.2020.12.003⟩
Article dans une revue hal-03549103 v1
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Inter-subject registration and application of the SIGMA rat brain atlas for regional labeling in functional ultrasound imaging

Benjamin Vidal , Marine Droguerre , Ludovic Venet , Marco Valdebenito , Franck Mouthon et al.
Journal of Neuroscience Methods, 2021, 355, pp.109139. ⟨10.1016/j.jneumeth.2021.109139⟩
Article dans une revue hal-04763118 v1
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Towards in vivo imaging of functionally active 5-HT1A receptors in schizophrenia: concepts and challenges

Oriane Razakarivony , Adrian Newman-Tancredi , Luc Zimmer
Translational Psychiatry, 2021, 11 (1), pp.22. ⟨10.1038/s41398-020-01119-3⟩
Article dans une revue hal-03160747 v1
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Pharmaco-fUS for Characterizing Drugs for Alzheimer’s Disease – The Case of THN201, a Drug Combination of Donepezil Plus Mefloquine

Benjamin Vidal , Marine Droguerre , Marco Valdebenito , Luc Zimmer , Michel Hamon et al.
Frontiers in Neuroscience, 2020, 14, pp.835. ⟨10.3389/fnins.2020.00835⟩
Article dans une revue hal-03160675 v1
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18F-F13640 PET imaging of functional receptors in humans

Matthieu Colom , Nicolas Costes , Jérôme Redouté , Frédéric Dailler , Florent Gobert et al.
European Journal of Nuclear Medicine and Molecular Imaging, 2020, 47 (1), pp.220-221. ⟨10.1007/s00259-019-04473-7⟩
Article dans une revue hal-02305453 v1
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Functional ultrasound imaging to study brain dynamics: Application of pharmaco-fUS to atomoxetine

Benjamin Vidal , Marine Droguerre , Ludovic Venet , Luc Zimmer , Marco Valdebenito et al.
Neuropharmacology, 2020, 179, pp.108273. ⟨10.1016/j.neuropharm.2020.108273⟩
Article dans une revue hal-03160725 v1
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Bayesian Estimation of the ntPET Model in Single-Scan Competition PET Studies

Zacharie Irace , Inés Mérida , Jérôme Redouté , Clara Fonteneau , Marie-Françoise Suaud-Chagny et al.
Frontiers in Physiology, 2020, 11, pp.498. ⟨10.3389/fphys.2020.00498⟩
Article dans une revue hal-03160651 v1
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Change in Expression of 5-HT6 Receptor at Different Stages of Alzheimer’s Disease: A Postmortem Study with the PET Radiopharmaceutical [18F]2FNQ1P

Pierre Courault , Stéphane Emery , Sandrine Bouvard , François Liger , Fabien Chauveau et al.
Journal of Alzheimer's Disease, 2020, 75 (4), pp.1329-1338. ⟨10.3233/JAD-191278⟩
Article dans une revue hal-03035778 v1
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Preclinical validation of [18F]2FNQ1P as a specific PET radiotracer of 5-HT6 receptors in rat, pig, non-human primate and human brain tissue

Stéphane Emery , Sylvain Fieux , Benjamin Vidal , Pierre Courault , Sandrine Bouvard et al.
Nuclear Medicine and Biology, 2020, 82-83, pp.57-63. ⟨10.1016/j.nucmedbio.2020.01.006⟩
Article dans une revue hal-03035781 v1
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Pharmacological MRI to investigate the functional selectivity of 5-HT1A receptor biased agonists

Benjamin Vidal , Radu Bolbos , Jérôme Redouté , Jean-Baptiste Langlois , Nicolas Costes et al.
Neuropharmacology, 2020, 172, pp.107867 -. ⟨10.1016/j.neuropharm.2019.107867⟩
Article dans une revue hal-03490240 v1
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PET imaging of the influence of physiological and pathological α‐synuclein on dopaminergic and serotonergic neurotransmission in mouse models

Élise Levigoureux , Caroline Bouillot , Thierry Baron , Luc Zimmer , Sophie Lancelot
CNS Neuroscience & Therapeutics, 2019, 25 (1), pp.57-68. ⟨10.1111/cns.12978⟩
Article dans une revue hal-04112106 v1
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Evaluation of Myelin Radiotracers in the Lysolecithin Rat Model of Focal Demyelination: Beware of Pitfalls!

Min Zhang , Gaëlle Hugon , Caroline Bouillot , Radu Bolbos , Jean-Baptiste Langlois et al.
Contrast Media and Molecular Imaging, 2019, 2019, pp.9294586. ⟨10.1155/2019/9294586⟩
Article dans une revue hal-02278818 v1
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Sécurisation de la prise en charge médicamenteuse des patients sous antipsychotiques : impact de la collaboration médico-pharmaceutique à la Maison d’Arrêt de Lyon-Corbas

C. Picard , L. Lalande , C. Bertin , C. Abel-Coindoz , A. Mauchauffée et al.
L'Encéphale, 2019, 45, pp.482 - 487. ⟨10.1016/j.encep.2019.05.008⟩
Article dans une revue hal-03488422 v1

Is there a Role for Agonist Radiopharmaceuticals in PET Neuroimaging?

Matthieu Colom , Benjamin Vidal , Zimmer Luc
Frontiers in Molecular Neuroscience, 2019, 12, pp.255. ⟨10.3389/fnmol.2019.00255⟩
Article dans une revue hal-02310324 v1
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Evaluation of [18F]2FP3 in pigs and non-human primates

Hanne Hansen , Cristian Constantinescu , Olivier Barret , Matthias Herth , Janus Magnussen et al.
Journal of Labelled Compounds and Radiopharmaceuticals, 2019, 62 (1), pp.34-42. ⟨10.1002/jlcr.3692⟩
Article dans une revue hal-02109621 v1
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Serotonin 5-HT 1A Receptor Biased Agonists Induce Different Cerebral Metabolic Responses: A [ 18 F]-Fluorodesoxyglucose Positron Emission Tomography Study in Conscious and Anesthetized Rats

Élise Levigoureux , Benjamin Vidal , Sylvain Fieux , Caroline Bouillot , Stéphane Emery et al.
ACS Chemical Neuroscience, 2019, 10 (7), pp.3108-3119. ⟨10.1021/acschemneuro.8b00584⟩
Article dans une revue hal-02305418 v1
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Meta-analysis in metastatic uveal melanoma to determine progression free and overall survival benchmarks: an international rare cancers initiative (IRCI) ocular melanoma study

L Khoja , E. G. Atenafu , S Suciu , S Leyvraz , T Sato et al.
Annals of Oncology, 2019, 30 (8), pp.1370-1380. ⟨10.1093/annonc/mdz176⟩
Article dans une revue hal-02466385 v1
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MAPSSIC, a Novel CMOS Intracerebral Positrons Probe for Deep Brain Imaging in Awake and Freely Moving Rats: A Monte Carlo Study

L. Ammour , J. Heymes , M. Bautista , S. Fieux , F. Gensolen et al.
IEEE Transactions on Radiation and Plasma Medical Sciences, 2019, 3 (3), pp.302-314. ⟨10.1109/TRPMS.2018.2881301⟩
Article dans une revue hal-02165345 v1
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In vivo biased agonism at 5-HT1A receptors: characterisation by simultaneous PET/MR imaging

Benjamin Vidal , Sylvain Fieux , Jérôme Redouté , Marjorie Villien , Frédéric Bonnefoi et al.
Neuropsychopharmacology, 2018, 43 (11), pp.2310-2319. ⟨10.1038/s41386-018-0145-2⟩
Article dans une revue hal-01917722 v1
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Amyloid-beta radiotracer [18F]BF-227 does not bind to cytoplasmic glial inclusions of post-mortem Multiple System Atrophy brain tissue

Mathieu Verdurand , Élise Levigoureux , Sophie Lancelot , Waël Zeinyeh , Thierry Billard et al.
Contrast Media and Molecular Imaging, 2018, 2018, ⟨10.1155/2018/9165458⟩
Article dans une revue hal-01691091 v1
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In Silico, in Vitro, and in Vivo Evaluation of New Candidates for α-Synuclein PET Imaging

Mathieu Verdurand , Élise Levigoureux , Waël Zeinyeh , Laurent Berthier , Meriem Mendjel-Herda et al.
Molecular Pharmaceutics, 2018, 15 (8), pp.3153-3166. ⟨10.1021/acs.molpharmaceut.8b00229⟩
Article dans une revue hal-01955442 v1
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The in Vitro Actions of Loxapine on Dopaminergic and Serotonergic Receptors. Time to Consider Atypical Classification of This Antipsychotic Drug?

Florian Ferreri , Dominique Drapier , Emmanuelle Baloche , Mehemed Ouzid , Luc Zimmer et al.
International Journal of Neuropsychopharmacology, 2018, 21 (4), pp.355-360. ⟨10.1093/ijnp/pyx102⟩
Article dans une revue hal-01696767 v1
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Implantable CMOS pixel sensor for positron imaging in rat brain

J. Heymes , L. Ammour , M. Bautista , G. Bertolone , A. Dorokhov et al.
Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 2018, 911, pp.19-24. ⟨10.1016/j.nima.2018.09.117⟩
Article dans une revue hal-01952201 v1

18F-F13640 preclinical evaluation in rodent, cat and primate as a 5-HT1A receptor agonist for PET neuroimaging

Benjamin Vidal , Sylvain Fieux , Matthieu Colom , Thierry Billard , Caroline Bouillot et al.
Brain Structure and Function, 2018, 223 (6), pp.2973-2988. ⟨10.1007/s00429-018-1672-7⟩
Article dans une revue hal-02107028 v1
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Ozone Atmospheric Pollution and Alzheimer’s Disease: From Epidemiological Facts to Molecular Mechanisms

Marine L. Croze , Luc Zimmer
Journal of Alzheimer's Disease, 2018, 62 (2), pp.503-522. ⟨10.3233/JAD-170857⟩
Article dans une revue hal-01785212 v1
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Quantitative longitudinal imaging of activated microglia as a marker of inflammation in the pilocarpine rat model of epilepsy using [ 11 C]-( R )-PK11195 PET and MRI

Josiane Yankam Njiwa , Nicolas Costes , Caroline Bouillot , Sandrine Bouvard , Sylvain Fieux et al.
Journal of Cerebral Blood Flow and Metabolism, 2017, 37 (4), pp.1251-1263. ⟨10.1177/0271678X16653615⟩
Article dans une revue hal-01571316 v1
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Hippocampal 5-HT 1A receptor expression changes in prodromal stages of Alzheimer's disease: Beneficial or deleterious?

Mathieu Verdurand , Luc Zimmer
Neuropharmacology, 2017, 123, pp.446-454. ⟨10.1016/j.neuropharm.2017.06.021⟩
Article dans une revue hal-01689706 v1
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Characterization and Reliability of [18F]2FNQ1P in Cynomolgus Monkeys as a PET Radiotracer for Serotonin 5-HT6 Receptors

Véronique Sgambato-Faure , Thierry Billard , Elise Metereau , Sandra Duperrier , Sylvain Fieux et al.
Frontiers in Pharmacology, 2017, 8, pp.471. ⟨10.3389/fphar.2017.00471⟩
Article dans une revue hal-01689720 v1
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Activity in the rat olfactory cortex is correlated with behavioral response to odor: a microPET study

Philippe Litaudon , Caroline Bouillot , Luc Zimmer , Nicolas Costes , Nadine Ravel
Brain Structure and Function, 2017, 222 (1), pp.577-586. ⟨10.1007/s00429-016-1235-8⟩
Article dans une revue hal-03773095 v1
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[11C]PF-3274167 as a PET radiotracer of oxytocin receptors: Radiosynthesis and evaluation in rat brain

Benjamin Vidal , Iuliia Karpenko , François Liger , Sylvain Fieux , Caroline Bouillot et al.
Nuclear Medicine and Biology, 2017, 55, pp.1-6. ⟨10.1016/j.nucmedbio.2017.07.008⟩
Article dans une revue hal-01689748 v1
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Contribution of Clinical Neuroimaging to the Understanding of the Pharmacology of Methylphenidate

Luc Zimmer
Trends in Pharmacological Sciences, 2017, 38 (7), pp.608-620. ⟨10.1016/j.tips.2017.04.001⟩
Article dans une revue hal-01689783 v1
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Differential effects of amyloid-beta 1–40 and 1–42 fibrils on 5-HT1A serotonin receptors in rat brain

Mathieu Verdurand , Fabien Chauveau , Alexia Daoust , Anne-Laure Morel , Frédéric Bonnefoi et al.
Neurobiology of Aging, 2016, 40, pp.11-21. ⟨10.1016/j.neurobiolaging.2015.12.008⟩
Article dans une revue hal-01291764 v1
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Marmoset Serotonin 5-HT 1A Receptor Mapping with a Biased Agonist PET Probe 18 F-F13714: Comparison with an Antagonist Tracer 18 F-MPPF in Awake and Anesthetized States

Chihiro Yokoyama , Aya Mawatari , Akihiro Kawasaki , Chiho Takeda , Kayo Onoe et al.
International Journal of Neuropsychopharmacology, 2016, 19 (12), pp.1 - 12. ⟨10.1093/ijnp/pyw079⟩
Article dans une revue hal-01488155 v1
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Imaging Dopamine and Serotonin Systems on MPTP Monkeys: A Longitudinal PET Investigation of Compensatory Mechanisms

Bénédicte Ballanger , Maude Beaudoin-Gobert , Sara Neumane , Justine Epinat , Elise Metereau et al.
Journal of Neuroscience, 2016, 36 (5), pp.1577 - 1589. ⟨10.1523/JNEUROSCI.2010-15.2016⟩
Article dans une revue hal-01571297 v1
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Selective serotonin 5-HT1A receptor biased agonists elicit distinct brain activation patterns: a pharmacoMRI study

G. Becker , R. Bolbos , N. Costes , J. Redouté , A. Newman-Tancredi et al.
Scientific Reports, 2016, 6 (1), pp.26633. ⟨10.1038/srep26633⟩
Article dans une revue hal-01488190 v1
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Pharmacological agonists for more-targeted CNS radio-pharmaceuticals

Luc Zimmer
Oncotarget, 2016, 7 (49), pp.80111 - 80112. ⟨10.18632/oncotarget.13418⟩
Article dans une revue hal-01488034 v1

A microPET comparison of the effects of etifoxine and diazepam on [11C]flumazenil uptake in rat brains

Caroline Bouillot , Frédéric Bonnefoi , François Liger , Luc Zimmer
Neuroscience Letters, 2016, 612, pp.74-79. ⟨10.1016/j.neulet.2015.11.042⟩
Article dans une revue hal-01264750 v1
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PIXSIC: A Wireless Intracerebral Radiosensitive Probe in Freely Moving Rats

Laure Balasse , Julia Maerk , Frédéric Pain , Aurélie Genoux , Sylvain Fieux et al.
Molecular Imaging, 2015, 14 (484–489), ⟨10.2310/7290.2015.00020⟩
Article dans une revue in2p3-01235714 v1

Selective trifluoromethylthiolation of heteroaromatic sp2 C-H bonds with the 2nd generation of trifluoromethanesulfenamide reagent

Alazet Sébastien , Zimmer Luc , Billard Thierry
Journal of Fluorine Chemistry, 2015, 171, pp.78-81
Article dans une revue hal-01152905 v1

PIXSIC, a Pixelated β(+)-Sensitive Probe for Radiopharmacological Investigations in Rat Brain: Binding Studies with [(18)F]MPPF.

Laure Balasse , Julia Maerk , Frédéric Pain , Aurélie Genoux , Sylvain Fieux et al.
Molecular Imaging and Biology, 2015, 17 (2), pp.163-167. ⟨10.1007/s11307-014-0785-5⟩
Article dans une revue hal-01105052 v1

Preclinical evaluation of [18F]2FNQ1P as the first fluorinated serotonin 5-HT6 radioligand for PET imaging

Guillaume Becker , Julie Colomb , Véronique Sgambato-Faure , Léon Tremblay , Thierry Billard et al.
European Journal of Nuclear Medicine and Molecular Imaging, 2015, 42 (3), pp.495-502. ⟨10.1007/s00259-014-2936-y⟩
Article dans une revue hal-01128421 v1

Electrophilic trifluoromethylthiolation of carbonyl compounds

Alazet Sébastien , Zimmer Luc , Billard Thierry
Chemistry - A European Journal, 2014, 20 (28), pp.8589-8593
Article dans une revue hal-01151171 v1
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A Multi-Atlas Based Method for Automated Anatomical Rat Brain MRI Segmentation and Extraction of PET Activity

Sophie Lancelot , Roxane Roche , Afifa Slimen , Caroline Bouillot , Élise Levigoureux et al.
PLoS ONE, 2014, 9 (10), pp.0109113. ⟨10.1371/journal.pone.0109113⟩
Article dans une revue hal-01128452 v1

Binding of the PET Radiotracer [18F]BF227 Does not Reflect the Presence of Alpha-Synuclein Aggregates in Transgenic Mice

Élise Levigoureux , Sophie Lancelot , Caroline Bouillot , Fabien Chauveau , Mathieu Verdurand et al.
Current Alzheimer Research, 2014, 11 (10), pp.955-960. ⟨10.2174/1567205011666141107154201⟩
Article dans une revue hal-01128444 v1

A Postmortem Study to Compare Agonist and Antagonist 5-HT1A Receptor-binding Sites in Alzheimer's Disease

Guillaume Becker , Nathalie Streichenberger , Thierry Billard , Adrian Newman-Tancredi , Luc Zimmer
CNS Neuroscience and Therapeutics, 2014, 20 (10), pp.930-934. ⟨10.1111/cns.12306⟩
Article dans une revue hal-01128433 v1

Syntheses, radiolabelings and in vitro evaluations of fluorinated PET radioligands of 5-HT6 serotoninergic receptors.

Julie Colomb , Guillaume Becker , Sylvain Fieux , Luc Zimmer , And Thierry Billard
Journal of Medicinal Chemistry, 2014, 57, pp.3884-90
Article dans une revue hal-01309560 v1

PET radiotracers for molecular imaging of serotonin 5-HT1A receptors

T. Billard , D. Le Bars , L. Zimmer
Current Medicinal Chemistry, 2014, 21 (1), pp.70-80. ⟨10.2174/09298673113209990215⟩
Article dans une revue istex hal-00947714 v1

Ultra high performance liquid chromatography as a tool for the discovery and the analysis of biomarkers of diseases: A review

L. Denoroy , L. Zimmer , B. Renaud , S. Parrot
Journal of Chromatography B - Analytical Technologies in the Biomedical and Life Sciences, 2013, 927, pp.37-53. ⟨10.1016/j.jchromb.2012.12.005⟩
Article dans une revue istex hal-00847427 v1

Base-Catalyzed Electrophilic Trifluoromethylthiolation of Terminal Alkynes

S. Alazet , L. Zimmer , T. Billard
Angewandte Chemie International Edition, 2013, 52 (41), pp.10814-10817. ⟨10.1002/anie.201305179⟩
Article dans une revue hal-00948085 v1

A wireless beta-microprobe based on pixelated silicon for in vivo brain studies in freely moving rats

Julia Maerk , Didier Benoit , Laure Balasse , Mathieu Benoit , Jean-Claude Clémens et al.
Physics in Medicine and Biology, 2013, 58, pp.4483 - 4500. ⟨10.1088/0031-9155/58/13/4483⟩
Article dans une revue in2p3-00837658 v1

Radiosynthesis and in vivo evaluation of fluorinated huprine derivates as PET radiotracers of acetylcholinesterase

Emilie da Costa Branquinho , Guillaume Becker , Cédric Bouteiller , Ludovic Jean , Pierre-Yves Renard et al.
Nuclear Medicine and Biology, 2013, 40 (4), pp.554-560. ⟨10.1016/j.nucmedbio.2013.02.004⟩
Article dans une revue istex hal-00847401 v1

Outcome of Poor-Grade Subarachnoid Hemorrhage as Determined by Biomarkers of Glucose Cerebral Metabolism

G.K. Barcelos , Y. Tholance , S. Grousson , B. Renaud , A. Perret-Liaudet et al.
Neurocritical Care, 2013, 18 (2), pp.234-244. ⟨10.1007/s12028-012-9810-1⟩
Article dans une revue hal-00847412 v1

Current status of positron emission tomography radiotracers for serotonin receptors in humans

L. Zimmer , D. Le Bars
Journal of Labelled Compounds and Radiopharmaceuticals, 2013, 56 (3-4), pp.105-113. ⟨10.1002/jlcr.3001⟩
Article dans une revue istex hal-00828326 v1
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Enhanced Anxiety Observed in Cocaine Withdrawn Rats Is Associated with Altered Reactivity of the Dorsomedial Prefrontal Cortex

Cynthia El Hage , Virginie Rappeneau , Adeline Etiévant , Anne-Laure Morel , Hélène Scarna et al.
PLoS ONE, 2012, 7 (8), pp.e43535. ⟨10.1371/journal.pone.0043535⟩
Article dans une revue hal-03630188 v1

MicroPET imaging of 5-HT1A receptors in rat brain: a test-retest [18F]MPPF study

N. Aznavour , C. Benkelfat , P. Gravel , A. Aliaga , P. Rosa-Neto et al.
European Journal of Nuclear Medicine and Molecular Imaging, 2012, 36 (1), pp.53-62. ⟨10.1007/s00259-008-0891-1⟩
Article dans une revue istex hal-00847462 v1
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Internalization of serotonin 5‐HT 1A autoreceptors as an imaging biomarker of antidepressant response

Luc Zimmer , Laurent Descarries
Wiley Interdisciplinary Reviews: Membrane Transport and Signaling, 2012, 1 (3), pp.239-245. ⟨10.1002/wmts.11⟩
Article dans une revue hal-00797786 v1

Behaviour of a genetic mouse model of depression in the learned helplessness paradigm

Laure Bougarel , Jérôme Guitton , Luc Zimmer , Jean-Marie Vaugeois , Malika El Yacoubi
Psychopharmacology, 2011, 215 (3), pp.595-605. ⟨10.1007/s00213-011-2218-3⟩
Article dans une revue istex hal-02185484 v1

Genetic association between helpless trait and depression-related phenotypes: evidence from crossbreeding studies with H/Rouen and NH/Rouen mice.

Malika El Yacoubi , Daniela Popa , Benoît Martin , Luc Zimmer , Michel Hamon et al.
International Journal of Neuropsychopharmacology, 2011, 15 (3), pp.363-374. ⟨10.1017/S1461145711000605⟩
Article dans une revue hal-00904261 v1

Genetic Inactivation of Prokineticin Receptor-1 Leads to Heart and Kidney Disorders

Mounia Boulberdaa , Gulen Turkeri , Kyoji Urayama , Mojdeh Dormishian , Cécilia Szatkowski et al.
Arteriosclerosis, Thrombosis, and Vascular Biology, 2011, 31 (4), pp.842-850. ⟨10.1161/ATVBAHA.110.222323⟩
Article dans une revue hal-02391087 v1

[18F]F15599, a novel 5-HT1A receptor agonist, as a radioligand for PET neuroimaging.

Laëtitia Lemoine , Mathieu Verdurand , Bernard Vacher , Elodie Blanc , Didier Le Bars et al.
European Journal of Nuclear Medicine and Molecular Imaging, 2010, 37 (3), pp.594-605. ⟨10.1007/s00259-009-1274-y⟩
Article dans une revue istex hal-00475580 v1

Effects of amyloid-beta peptides on the serotoninergic 5-HT(1A) receptors in the rat hippocampus.

Mathieu Verdurand , Anne Bérod , Didier Le Bars , Luc Zimmer
Neurobiol Aging, 2009, 32 (1), pp.103-114. ⟨10.1016/j.neurobiolaging.2009.01.008⟩
Article dans une revue istex hal-00397792 v1

F15063, a potential antipsychotic with dopamine D2/D3 receptor antagonist, 5-HT1A receptor agonist and dopamine D4 receptor partial agonist properties: Influence on neuronal firing and neurotransmitter release

Marie-Bernadette Assié , Ouissame Mnie-Filali , Véronique Ravailhe , Christelle Benas , Marc Marien et al.
European Journal of Pharmacology, 2009, 607 (1-3), pp.74-83. ⟨10.1016/j.ejphar.2009.02.001⟩
Article dans une revue istex hal-04303724 v1

A distinct [18F]MPPF PET profile in amnestic mild cognitive impairment compared to mild Alzheimer's disease

L. Truchot , N. Costes , L. Zimmer , B. Laurent , D. Le Bars et al.
NeuroImage, 2008, 15 (40), pp.(1251-6)
Article dans une revue hal-00443483 v1

The potential of a radiosensitive intracerebral probe to monitor 18F-MPPF binding in mouse hippocampus in vivo

A. Desbrée , M. Verdurand , J. Godart , André Dubois , R. Mastrippolito et al.
Journal of Nuclear Medicine, 2008, 49 (7), pp.1155-1161. ⟨10.2967/jnumed.107.050047⟩
Article dans une revue hal-03002294 v1

Simultaneous in vivo magnetic resonance imaging and radioactive measurements with the β-MicroProbe

A. Desbrée , L. Rbah , J.-B. Langlois , D. Grenier , R. Mastrippolito et al.
European Journal of Nuclear Medicine and Molecular Imaging, 2007, 34 (11), pp.1868-1872. ⟨10.1007/s00259-007-0475-5⟩
Article dans une revue istex hal-03015570 v1

Up-regulation of hippocampal serotonin metabolism in mild cognitive impairment

L. Truchot , N. Costes , L. Zimmer , B. Laurent , D. Le Bars et al.
Neurology, 2007, 69 (10), pp.(1012-7)
Article dans une revue hal-00443482 v1

Raytest ClearPET, a new generation small animal PET scanner

Pablo Sempere Roldan , Emmanuel Chereul , Oliver Dietzel , Luc Magnier , Christian Pautrot et al.
Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 2007, 571 (1-2), pp.498-501. ⟨10.1016/j.nima.2006.10.143⟩
Article dans une revue istex hal-00443461 v1

Simultaneous in vivo Magnetic Resonance Imaging and Radioactive Measurements by the B-MicroProbe

A. Desbrée , L. Rbah , J. B. Langlois , D. Grenier , R. Mastrippolito et al.
European Journal of Nuclear Medicine and Molecular Imaging, 2007, 34 (11), pp.1868-72
Article dans une revue hal-00443228 v1

A new multimodality system for quantitative in vivo studies in small animals: combination of nuclear magnetic resonance and the radiosensitive beta-MicroProbe

E. A. Desbré , Frederic Pain , H. Gurden , L. Pinot , D. Grenier et al.
IEEE Transactions on Nuclear Science, 2005, 52 (5), pp.1281-1287
Article dans une revue hal-00443227 v1

A new multimodality system for quantitative in vivo studies in small animals: combination of nuclear magnetic resonance and the radiosensitive$\beta$-MicroProbe

A. Desbree , Frederic Pain , H. Gurden , L. Pinot , D. Grenier et al.
IEEE Transactions on Nuclear Science, 2005, 52, pp.1281-1287. ⟨10.1109/TNS.2005.858216⟩
Article dans une revue in2p3-00025341 v1

The ANIMAGE project: a multimodal imaging platform for small animal research

D. Sappey-Marinier , O. Beuf , C. Billotey , E. Chereul , J. Dupuy et al.
Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 2004, 527, pp.117-123. ⟨10.1016/j.nima.2004.03.092⟩
Article dans une revue istex hal-01883295 v1

Combining the radiosensitive Beta MicroProbe to Nuclear Magnetic Resonance: theoretical approach for in vivo studies in small animals

A. Desbrée , Frederic Pain , H. Gurden , L. Zimmer , L. Pinot et al.
Journal of Neuroscience Methods, 2004, 140, pp.47-52. ⟨10.1016/j.jneumeth.2004.03.029⟩
Article dans une revue istex in2p3-00025780 v1

Displacement of the PET ligand18F-MPPF by the electrically evoked serotonin release in the rat hippocampus

Latifa Rbah , Vincent Leviel , Luc Zimmer
Synapse, 2003, 49 (4), pp.239-245. ⟨10.1002/syn.10235⟩
Article dans une revue istex inserm-02437128 v1

Neither the density nor function of striatal dopamine transporters were influenced by chronic n-3 polyunsaturated fatty acid deficiency in rodents

Ercem Kodas , Guylène Page , Luc Zimmer , Sylvie Vancassel , Denis Guilloteau et al.
Neuroscience Letters, 2002, 321 (1-2), pp.95-99. ⟨10.1016/s0304-3940(01)02481-8⟩
Article dans une revue istex hal-02675958 v1

The potential of the β-Microprobe, an intracerebral radiosensitive probe, to monitor the [18F]MPPF binding in the rat dorsal raphe nucleus

L. Zimmer , Frederic Pain , G. Mauger , A. Plenevaux , D. Le Bars et al.
European Journal of Nuclear Medicine and Molecular Imaging, 2002, 29, pp.1237-1247. ⟨10.1007/s00259-002-0866-6⟩
Article dans une revue istex in2p3-00023833 v1

SIC, an intracerebral beta(+)-range-sensitive probe for radiopharmacology investigations in small laboratory animals: Binding studies with C-11-raclopride

L. Zimmer , W. Hassoun , Frederic Pain , F. Bonnefoi , P. Laniece et al.
Journal of Nuclear Medicine, 2002, 43, pp.227-233
Article dans une revue in2p3-00013611 v1

The dopamine mesocorticolimbic pathway is affected by deficiency in n-3 polyunsaturated fatty acids

Luc Zimmer , Sylvie Vancassel , Sylvain Cantagrel , Patrick Breton , Séraphin Delamanche et al.
The American Journal of Clinical Nutrition, 2002, 75 (4), pp.662-667. ⟨10.1093/ajcn/75.4.662⟩
Article dans une revue hal-02675380 v1

Polyunsaturated fatty acids and cerebral function: focus on monoaminergic neurotransmission

S. Chalon , Sylvie Vancassel , L. Zimmer , D. Guilloteau , Georges Durand
Lipids, 2001, 36 (9), pp.937-44. ⟨10.1007/s11745-001-0804-7⟩
Article dans une revue istex hal-02683336 v1
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Modification of dopamine neurotransmission in the nucleus accumbens of rats deficient in n-3 polyunsaturated fatty acids

Luc Zimmer , Sylvie Vancassel , Georges Durand , Denis Guilloteau , Sylvie Bodard et al.
Journal of Lipid Research, 2000, 41 (1), 9 p
Article dans une revue hal-02697599 v1

Chronic n-3 polyunsaturated fatty acid deficiency alters dopamine vesicle density in the rat frontal cortex

L. Zimmer , Serge Delpal , D. Guilloteau , Josiane Aïoun , G. Durand et al.
Neuroscience Letters, 2000, 284, pp.25-28
Article dans une revue hal-02696603 v1

Chronic n-3 polyunsaturated fatty acid diet-deficiency acts on dopamine metabolism in the rat frontal cortex: a microdialysis study

L. Zimmer , S. Hembert , G. Durand , Pauline Breton , D. Guilloteau et al.
Neuroscience Letters, 1998, 240, pp.177-181
Article dans une revue hal-02697597 v1
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The SB-258585, a 5-HT6 antagonist that blocks serotonin transmission in striatum can induce loss of food motivation and behavioral disturbances in non-human primate.

Léon Tremblay , Mathilde Pitoy , Lisa Gauthier , Julie Maulavé , Justine Debatisse et al.
NeuroFrance, May 2023, Lyon, France
Poster de conférence hal-04983922 v1
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5-HT1A biased agonists induce different hemodynamic responses, a pharmacological MRI study

Benjamin Vidal , Radu Bolbos , Jérôme Redouté , Jean-Baptiste Langlois , Sylvain Fieux et al.
ECNP, 2017, Paris, France
Poster de conférence hal-04273484 v1

Physical Characterization of a Wireless Radiotracer Detection System Based on Pixelated Silicon for in Vivo Brain Studies in Freely Moving Rats

Julia Maerk , Didier Benoit , Laure Balasse , Mathieu Benoit , Jean-Claude Clémens et al.
2012 Nuclear Science Symposium, Medical Imaging Conference & Workshop on Room-Temperature Semiconductor X-Ray and Gamma-Ray Detectors, Oct 2012, Anaheim, Californie, United States
Poster de conférence in2p3-00757534 v1

PIXSIC-Characterisation of a Beta+ Intracerebral Wireless Probe for Functtional Imaging Coupled with Behavioural Studies Performed on Freely Moving Rats

Julia Maerk , Laure Balasse , Didier Benoit , Mathieu Benoit , Jean-Claude Clémens et al.
WMIC'2012 World Molecular Imaging Congress, Sep 2012, Dublin, Ireland
Poster de conférence in2p3-00869594 v1

Physical characterization of a wireless radiotracer detection system based on pixalated Silicon for in vivo brain studies in freely moving rats

Julia Maerk , Didier Benoit , Laure Balasse , Mathieu Benoit , Jean-Claude Clémens et al.
IX ième Journée Scientifique BCP, Dec 2012, Marseille, France
Poster de conférence in2p3-00767714 v1

New Concept of a Submillimetric Pixellated Silicon Detector for in Vivo Brain Studies in Freely Moving Rodents

J. Maerk , D. Benoit , M. Benoit , J.-C. Clémens , D. Fougeron et al.
2011 World Molecular Imaging Congress, Sep 2011, San Diego, United States
Poster de conférence in2p3-00628952 v1

The effects of a total sleep deprivation on the brain 5-HT1A receptor binding: A pet study with [F-18]MPPF

Yazid Lakhdarchaouche , Thierry Faivre , Nicolas Costes , Luc Zimmer , Alain Nicolas et al.
24th CINP Congress, Jun 2004, Paris, France. NTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, 7, pp.S286, 2004
Poster de conférence hal-02351542 v1

Neurotransmission dopaminergique et nutrition : la déficience alimentaire en acides gras polyinsaturés n-3 modifie le système dopaminergique cortico-limbique chez le rat

Luc Zimmer , Sylvie Vancassel , Denis Guilloteau , Georges Durand , Sylvie Chalon
3. Colloque de la Société des Neurosciences, 1999, Marseille, France. 1999
Poster de conférence hal-02840396 v1

MAPSSIC, a beta<sup>+</sup> implantable microprobe for neuroimaging of awake and freely moving rats: first sensor characterization and in vivo imaging simulations

Samir El Ketara , Franck Agnese , Luis Ammour , Jérôme Baudot , Sandrine Bouvard et al.
2023 IEEE Nuclear Science Symposium (NSS), Medical Imaging Conference (MIC) and Room Temperature Semiconductor Detector (RTSD) Conference (NSS/MIC 2023), Nov 2023, Vancouver, Canada. ⟨10.1109/NSSMICRTSD49126.2023.10338464⟩
Communication dans un congrès hal-04381878 v1
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MAPSSIC, a communicating MAPS-based intracerebral positrons probe for deep brain imaging in awake and freely-moving rats

F. Gensolen , L. Ammour , M. Bautista , J. Heymes , S. Fieux et al.
6th International Conference on Advancements in Nuclear Instrumentation Measurement Methods and their Applications, Jun 2019, Protoroz, Slovenia. pp.09002, ⟨10.1051/epjconf/202022509002⟩
Communication dans un congrès hal-02458778 v1
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Stability and disassembly of alpha-synuclein fibrils

Mathieu Verdurand , Lucile Mazière , Marion Hérault , Anthony Fourier , Isabelle Quadrio et al.
13th International Conference on Alzheimer’s & Parkinson’s diseases (AD/PD), Mar 2017, Vienne, Austria. pp.1412
Communication dans un congrès hal-01466122 v1

Plate-forme d’imagerie préclinique AnimAge du CERMEP

Radu Bolbos , Jean-Baptiste Langlois , Caroline Bouillot , Véronique Gualda , Luc Zimmer
1er Congrès National d'Imagerie du Vivant (CNIV), Feb 2016, Paris, France
Communication dans un congrès hal-01285493 v1
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A screening assay in the search of an alpha-synuclein PET radioligand

Mathieu Verdurand , Meriem Mendjel-Herda , Élise Levigoureux , Sophie Lancelot , Waël Zeinyeh et al.
World Molecular Imaging Congress (WMIC 2015), Sep 2015, Honolulu, United States
Communication dans un congrès hal-01207698 v1
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In vivo evaluation of a hybrid nanoparticle for molecular imaging of amyloid aggregation

E. Ong , F. Vadcard , M. Verdurand , H. Rositi , F. Peyrin et al.
10th annual meeting of the European Society for Molecular Imaging (ESMI) - European Molecular Imaging Meeting (EMIM), Mar 2015, Tübingen, Germany
Communication dans un congrès hal-01207666 v1
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A screening assay in the search of an alpha-synuclein PET radioligand

Mathieu Verdurand , Meriem Mendjel-Herda , Élise Levigoureux , Sophie Lancelot , Waël Zeinyeh et al.
10th annual meeting of the European Society for Molecular Imaging (ESMI) - European Molecular Imaging Meeting (EMIM), Mar 2015, Tübingen, Germany
Communication dans un congrès hal-01207682 v1

A post-mortem study to compare the 5-HT1A receptor binding of a PET agonist and a PET antagonist in Alzheimer's disease

G. Becker , N. Streichenberger , T. Billard , B. Vacher , A. Newman-Tancredi et al.
Annual Congress of the European Association of Nuclear Medicine 2013, Oct 2013, Lyon, France
Communication dans un congrès hal-00948356 v1

PIXSIC, a wireless radiosensitive intracerebral probe to monitor PET radiotracers in anaesthetized and awake rat

L. Balasse , J. Maerk , S. Fieux , Frederic Pain , P. Gisquet et al.
Annual Congress of the European Association of Nuclear Medicine 2013, Oct 2013, Lyon, France
Communication dans un congrès hal-00948325 v1

Initial evaluation of [18F]F13714, a novel 5-HT1A receptor agonist in non-human primates

A. Tavares , G. Becker , O. Barret , T. Morley , D. Alagille et al.
Annual Congress of the European Association of Nuclear Medicine 2013, Oct 2013, Lyon, France
Communication dans un congrès hal-00948404 v1

Preclinical evaluation of serotonin 5-HT6 receptor radioligands for PET imaging

G. Becker , J. Colomb , T. Billard , L. Zimmer
Annual Congress of the European Association of Nuclear Medicine 2013, Oct 2013, Lyon, France
Communication dans un congrès hal-00948359 v1

Radiosynthesis and radiopharmacological evaluation of fluorinated PET radioligands for the 5-HT6 receptors

G. Becker , J. Colomb , T. Billard , L. Zimmer
Society of Nuclear Medicine Congress 2013, Jun 2013, Vancouver, Canada. pp.326
Communication dans un congrès hal-00948473 v1

Potential of the wireless radiosensitive intracerebral probe PIXSIC to monitor PET radiotracers in anaesthetized and awake rat

Laure Balasse , Julia Maerk , Sylvain Fieux , Frédéric Pain , Aurélie Genoux et al.
WMIC'2013, World Molecular Imaging Congress, Savannah, Georgia, USA, Sep 2013, Savannah, Georgia, United States
Communication dans un congrès in2p3-01069277 v1

A multi-atlas based method for automated anatomical rat brain MRI segmentation and extraction of PET kinetics

Sophie Lancelot , Alexander Hammers , Jean-Baptiste Langlois , Caroline Bouillot , Luc Zimmer et al.
Nouvelles méthodologies en imagerie du vivant, Dec 2012, Lyon, France
Communication dans un congrès hal-00828672 v1

A multi-atlas based method for automated anatomical rat brain MRI segmentation and extraction of PET kinetics

Sophie Lancelot , Alexander Hammers , Élise Levigoureux , Jean-Baptiste Langlois , Luc Zimmer et al.
9th International Symposium on Functional Neuroreceptor Mapping of the Living Brain (NRM), Aug 2012, Baltimore, United States. pp.S171-S172
Communication dans un congrès hal-00830156 v1

The ANIMAGE project: a multimodal imaging platform for small animal research

D. Sappey-Marinier , Olivier Beuf , C. Billotey , E. Chereul , J. Dupuy et al.
2. International Conference on Imaging Technologies in Biomedical Sciences, May 2003, Athènes, Greece
Communication dans un congrès hal-02763821 v1

PUFA and cerebral function: focus on monoaminergic neurotransmitters

Sylvie Chalon , Sylvie Vancassel , Luc Zimmer , Denis Guilloteau , Georges Durand
PUFA in Maternal and Child Health, 2000, Kansas City, United States
Communication dans un congrès hal-02840465 v1