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Serotonin 5-HT1A receptor biased agonists: The challenge of translating an innovative neuropharmacological concept into therapeutics
Luc Zimmer
,
Adrian Newman-Tancredi
Article dans une revue
hal-04914119
v1
|
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Pharmacodynamic, pharmacokinetic and rat brain receptor occupancy profile of NLX-112, a highly selective 5-HT1A receptor biased agonist
Ronan Depoortère
,
Andrew Mccreary
,
Benjamin Vidal
,
Mark Varney
,
Luc Zimmer
et al.
Article dans une revue
hal-04763126
v1
|
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WAY-208466, a 5-HT6 receptor agonist, increases food motivation in primates: A behavioural and PET imaging study opening perspectives in eating disorders
Mathilde Pitoy
,
Julie Maulavé
,
Lisa Gauthier
,
Justine Debatisse
,
Nicolas Costes
et al.
Article dans une revue
hal-04811333
v1
|
|
NMDA antagonist agents for the treatment of symptoms in autism spectrum disorder: a systematic review and meta-analysis
Marie-Lou Dessus-Gilbert
,
Mikail Nourredine
,
Luc Zimmer
,
Benjamin Rolland
,
Marie-Maude Geoffray
et al.
Article dans une revue
(article de synthèse)
hal-04932440
v1
|
|
Toward Multidisciplinary Tools for Complex Clinical Psychopharmacology Cases: A Qualitative Study with French Healthcare Professionals
Matthieu Lebrat
,
Rachel Megard
,
Anne-Cecile Gallo Blandin
,
Nicolas Franck
,
Luc Zimmer
Article dans une revue
hal-04842732
v1
|
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A revisited version of the disputatio for pharmacological training: An educational study
Louise Carton
,
Perle Totoson
,
Edouard-Jules Laforgue
,
Jean-Marc Pelerin
,
Thomas Portier-Feunteun
et al.
Article dans une revue
hal-04805817
v1
|
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SB-258585 reduces food motivation while blocking 5-HT$_6$ receptors in the non-human primate striatum
Mathilde Pitoy
,
Lisa Gauthier
,
Justine Debatisse
,
Julie Maulavé
,
Elise Météreau
et al.
Article dans une revue
hal-04566627
v1
|
|
[18F]RS-127445 radiosynthesis and evaluation as a 5-HT2B receptor PET radiotracer in rat brain
Violette Richin
,
Caroline Bouillot
,
Sandrine Bouvard
,
Pierre Courault
,
Sophie Lancelot
et al.
Article dans une revue
hal-04794525
v1
|
|
Preclinical investigation of the effect of stress on the binding of [18F]F13640, a 5-HT1A radiopharmaceutical
Pierre Courault
,
Sandrine Bouvard
,
Caroline Bouillot
,
Luc Zimmer
,
Sophie Lancelot
Article dans une revue
hal-04794527
v1
|
|
Identification of factors associated with hospitalization in an outpatient population with mental health conditions: a case–control study
Matthieu Lebrat
,
Rachel Megard
,
Cédric Dananché
,
Luc Zimmer
,
Julien Plasse
et al.
Article dans une revue
hal-04824949
v1
|
|
Characterization of IMIC, an implantable needle-shaped positron sensitive monolithic active pixel sensor for preclinical molecular neuroimaging
S El Ketara
,
F Agnese
,
L Ammour
,
S Bouvard
,
O Clausse
et al.
Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 2024, 1064, pp.169456. ⟨10.1016/j.nima.2024.169456⟩
Article dans une revue
hal-04592637
v1
|
|
Pharmacodynamic, pharmacokinetic and rat brain receptor occupancy profile of NLX-112, a highly selective 5-HT 1A receptor biased agonist
Ronan Y Depoortère
,
Andrew C Mccreary
,
Benjamin Vidal
,
Mark A Varney
,
Luc Zimmer
et al.
Article dans une revue
hal-04932477
v1
|
|
Not so paradoxical … Neurobiology of attention deficit–hyperactivity disorder (ADHD) and therapeutic mode of action of psychostimulants
Benjamin Rolland
,
Luc Zimmer
,
Hugo Prunier
,
Guillaume Sescousse
Article dans une revue
hal-04932443
v1
|
|
Perspectives on obesity imaging: [18F]2FNQ1P a specific 5-HT6 brain PET radiotracer
Pierre Courault
,
Sandrine Bouvard
,
Caroline Bouillot
,
Radu Bolbos
,
Waël Zeinyeh
et al.
Article dans une revue
hal-04793046
v1
|
|
Toward Functional PET Imaging of the Spinal Cord
Pierre Courault
,
Luc Zimmer
,
Sophie Lancelot
Article dans une revue
hal-04794514
v1
|
|
[18F]F13640: a selective agonist PET radiopharmaceutical for imaging functional 5-HT1A receptors in humans
Pierre Courault
,
Sophie Lancelot
,
Nicolas Costes
,
Matthieu Colom
,
Didier Le Bars
et al.
Article dans une revue
hal-04528816
v1
|
|
A consensus protocol for functional connectivity analysis in the rat brain
Joanes Grandjean
,
Gabriel Desrosiers-Gregoire
,
Cynthia Anckaerts
,
Diego Angeles-Valdez
,
Fadi Ayad
et al.
Article dans une revue
hal-04268925
v1
|
|
Multimodal imaging study of the 5-HT1A receptor biased agonist, NLX-112, in a model of L-DOPA-induced dyskinesia
Sarah Chaib
,
Benjamin Vidal
,
Caroline Bouillot
,
Ronan Depoortere
,
Adrian Newman-Tancredi
et al.
Article dans une revue
hal-04763124
v1
|
|
Single subanesthetic dose of ketamine produces delayed impact on brain [18F]FDG PET imaging and metabolic connectivity in rats
Sarah Chaib
,
Caroline Bouillot
,
Sandrine Bouvard
,
Benjamin Vidal
,
Luc Zimmer
et al.
Article dans une revue
hal-04528862
v1
|
|
3D-printed dual holder system for simultaneous rat PET scanning: design and influence on quantification
Caroline Bouillot
,
Sébastien Daligault
,
Radu Bolbos
,
Nicolas Costes
,
Luc Zimmer
Article dans une revue
hal-04930517
v1
|
|
Anti-CD20 therapies in multiple sclerosis: From pathology to the clinic
Jérôme de Sèze
,
Elisabeth Maillart
,
Antoine Gueguen
,
David‐axel Laplaud
,
Laure Michel
et al.
Article dans une revue
(article de synthèse)
hal-04086889
v1
|
|
Positron Emission Tomography for the Discovery of New Drugs in Psychiatry
Luc Zimmer
Article dans une revue
hal-04528842
v1
|
|
Recent applications of positron emission tomographic (PET) imaging in psychiatric drug discovery
Luc Zimmer
Article dans une revue
(article de synthèse)
hal-04815147
v1
|
|
Author Correction: A consensus protocol for functional connectivity analysis in the rat brain
Joanes Grandjean
,
Gabriel Desrosiers-Gregoire
,
Cynthia Anckaerts
,
Diego Angeles-Valdez
,
Fadi Ayad
et al.
Article dans une revue
inserm-04917769
v1
|
|
Pharmaco-fUS in cognitive impairment: Lessons from a preclinical model
Benjamin Vidal
,
Mickaël Pereira
,
Marco Valdebenito
,
Louis Vidal
,
Franck Mouthon
et al.
Article dans une revue
hal-04763123
v1
|
|
PET metabolic imaging of time-dependent reorganization of olfactory cued fear memory networks in rats
Anne-Marie Mouly
,
Caroline Bouillot
,
Nicolas Costes
,
Luc Zimmer
,
Nadine Ravel
et al.
Article dans une revue
hal-03772913
v1
|
|
Impaired Local and Long-Range Brain Connectivity and Visual Response in a Genetic Rat Model of Hyperactivity Revealed by Functional Ultrasound
Marine Droguerre
,
Benjamin Vidal
,
Marco Valdebenito
,
Franck Mouthon
,
Luc Zimmer
et al.
Article dans une revue
hal-04763120
v1
|
|
Comparative diagnosis interest of NfL and pNfH in CSF and plasma in a context of FTD–ALS spectrum
Jean Escal
,
Anthony Fourier
,
Maïté Formaglio
,
Luc Zimmer
,
Emilien Bernard
et al.
Article dans une revue
hal-04796041
v1
|
|
[18F]F13640, a 5-HT1A Receptor Radiopharmaceutical Sensitive to Brain Serotonin Fluctuations
Matthieu Colom
,
Benjamin Vidal
,
Sylvain Fieux
,
Jérôme Redouté
,
Nicolas Costes
et al.
Article dans une revue
hal-03407570
v1
|
|
Innovative approaches in CNS drug discovery
Mathieu Charvériat
,
Vincent Lafon
,
Franck Mouthon
,
Luc Zimmer
Article dans une revue
hal-03160773
v1
|
|
Cluster headache: state of the art of pharmacological treatments and therapeutic perspectives
Pierre Courault
,
Genevieve Demarquay
,
Luc Zimmer
,
Sophie Lancelot
Fundamental & Clinical Pharmacology, 2021, Themed series on Neuropharmacology, 35 (3), pp.595-619. ⟨10.1111/fcp.12636⟩
Article dans une revue
hal-04799225
v1
|
|
Different alterations of agonist and antagonist binding to 5-HT1A receptor in a rat model of Parkinson's disease and levodopa-induced dyskinesia : a microPET study
Benjamin Vidal
,
Élise Levigoureux
,
Sarah Chaib
,
Caroline Bouillot
,
Thierry Billard
et al.
Article dans une revue
hal-03407557
v1
|
|
Clinical research in psychopharmacology, the current situation and its perspectives. A conversation with Pierre-Michel Llorca
Pierre-Michel Llorca
,
Luc Zimmer
Article dans une revue
hal-03549103
v1
|
|
Inter-subject registration and application of the SIGMA rat brain atlas for regional labeling in functional ultrasound imaging
Benjamin Vidal
,
Marine Droguerre
,
Ludovic Venet
,
Marco Valdebenito
,
Franck Mouthon
et al.
Article dans une revue
hal-04763118
v1
|
|
Towards in vivo imaging of functionally active 5-HT1A receptors in schizophrenia: concepts and challenges
Oriane Razakarivony
,
Adrian Newman-Tancredi
,
Luc Zimmer
Article dans une revue
hal-03160747
v1
|
|
Pharmaco-fUS for Characterizing Drugs for Alzheimer’s Disease – The Case of THN201, a Drug Combination of Donepezil Plus Mefloquine
Benjamin Vidal
,
Marine Droguerre
,
Marco Valdebenito
,
Luc Zimmer
,
Michel Hamon
et al.
Article dans une revue
hal-03160675
v1
|
|
18F-F13640 PET imaging of functional receptors in humans
Matthieu Colom
,
Nicolas Costes
,
Jérôme Redouté
,
Frédéric Dailler
,
Florent Gobert
et al.
Article dans une revue
hal-02305453
v1
|
|
Functional ultrasound imaging to study brain dynamics: Application of pharmaco-fUS to atomoxetine
Benjamin Vidal
,
Marine Droguerre
,
Ludovic Venet
,
Luc Zimmer
,
Marco Valdebenito
et al.
Article dans une revue
hal-03160725
v1
|
|
Bayesian Estimation of the ntPET Model in Single-Scan Competition PET Studies
Zacharie Irace
,
Inés Mérida
,
Jérôme Redouté
,
Clara Fonteneau
,
Marie-Françoise Suaud-Chagny
et al.
Article dans une revue
hal-03160651
v1
|
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Change in Expression of 5-HT6 Receptor at Different Stages of Alzheimer’s Disease: A Postmortem Study with the PET Radiopharmaceutical [18F]2FNQ1P
Pierre Courault
,
Stéphane Emery
,
Sandrine Bouvard
,
François Liger
,
Fabien Chauveau
et al.
Article dans une revue
hal-03035778
v1
|
|
Preclinical validation of [18F]2FNQ1P as a specific PET radiotracer of 5-HT6 receptors in rat, pig, non-human primate and human brain tissue
Stéphane Emery
,
Sylvain Fieux
,
Benjamin Vidal
,
Pierre Courault
,
Sandrine Bouvard
et al.
Article dans une revue
hal-03035781
v1
|
|
Pharmacological MRI to investigate the functional selectivity of 5-HT1A receptor biased agonists
Benjamin Vidal
,
Radu Bolbos
,
Jérôme Redouté
,
Jean-Baptiste Langlois
,
Nicolas Costes
et al.
Article dans une revue
hal-03490240
v1
|
|
PET imaging of the influence of physiological and pathological α‐synuclein on dopaminergic and serotonergic neurotransmission in mouse models
Élise Levigoureux
,
Caroline Bouillot
,
Thierry Baron
,
Luc Zimmer
,
Sophie Lancelot
Article dans une revue
hal-04112106
v1
|
|
Evaluation of Myelin Radiotracers in the Lysolecithin Rat Model of Focal Demyelination: Beware of Pitfalls!
Min Zhang
,
Gaëlle Hugon
,
Caroline Bouillot
,
Radu Bolbos
,
Jean-Baptiste Langlois
et al.
Article dans une revue
hal-02278818
v1
|
|
Sécurisation de la prise en charge médicamenteuse des patients sous antipsychotiques : impact de la collaboration médico-pharmaceutique à la Maison d’Arrêt de Lyon-Corbas
C. Picard
,
L. Lalande
,
C. Bertin
,
C. Abel-Coindoz
,
A. Mauchauffée
et al.
Article dans une revue
hal-03488422
v1
|
|
Is there a Role for Agonist Radiopharmaceuticals in PET Neuroimaging?
Matthieu Colom
,
Benjamin Vidal
,
Zimmer Luc
Article dans une revue
hal-02310324
v1
|
|
Evaluation of [18F]2FP3 in pigs and non-human primates
Hanne Hansen
,
Cristian Constantinescu
,
Olivier Barret
,
Matthias Herth
,
Janus Magnussen
et al.
Journal of Labelled Compounds and Radiopharmaceuticals, 2019, 62 (1), pp.34-42. ⟨10.1002/jlcr.3692⟩
Article dans une revue
hal-02109621
v1
|
|
Serotonin 5-HT 1A Receptor Biased Agonists Induce Different Cerebral Metabolic Responses: A [ 18 F]-Fluorodesoxyglucose Positron Emission Tomography Study in Conscious and Anesthetized Rats
Élise Levigoureux
,
Benjamin Vidal
,
Sylvain Fieux
,
Caroline Bouillot
,
Stéphane Emery
et al.
Article dans une revue
hal-02305418
v1
|
|
Meta-analysis in metastatic uveal melanoma to determine progression free and overall survival benchmarks: an international rare cancers initiative (IRCI) ocular melanoma study
L Khoja
,
E. G. Atenafu
,
S Suciu
,
S Leyvraz
,
T Sato
et al.
Article dans une revue
hal-02466385
v1
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MAPSSIC, a Novel CMOS Intracerebral Positrons Probe for Deep Brain Imaging in Awake and Freely Moving Rats: A Monte Carlo Study
L. Ammour
,
J. Heymes
,
M. Bautista
,
S. Fieux
,
F. Gensolen
et al.
Article dans une revue
hal-02165345
v1
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In vivo biased agonism at 5-HT1A receptors: characterisation by simultaneous PET/MR imaging
Benjamin Vidal
,
Sylvain Fieux
,
Jérôme Redouté
,
Marjorie Villien
,
Frédéric Bonnefoi
et al.
Article dans une revue
hal-01917722
v1
|
|
Amyloid-beta radiotracer [18F]BF-227 does not bind to cytoplasmic glial inclusions of post-mortem Multiple System Atrophy brain tissue
Mathieu Verdurand
,
Élise Levigoureux
,
Sophie Lancelot
,
Waël Zeinyeh
,
Thierry Billard
et al.
Article dans une revue
hal-01691091
v1
|
|
In Silico, in Vitro, and in Vivo Evaluation of New Candidates for α-Synuclein PET Imaging
Mathieu Verdurand
,
Élise Levigoureux
,
Waël Zeinyeh
,
Laurent Berthier
,
Meriem Mendjel-Herda
et al.
Article dans une revue
hal-01955442
v1
|
|
The in Vitro Actions of Loxapine on Dopaminergic and Serotonergic Receptors. Time to Consider Atypical Classification of This Antipsychotic Drug?
Florian Ferreri
,
Dominique Drapier
,
Emmanuelle Baloche
,
Mehemed Ouzid
,
Luc Zimmer
et al.
Article dans une revue
hal-01696767
v1
|
|
Implantable CMOS pixel sensor for positron imaging in rat brain
J. Heymes
,
L. Ammour
,
M. Bautista
,
G. Bertolone
,
A. Dorokhov
et al.
Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 2018, 911, pp.19-24. ⟨10.1016/j.nima.2018.09.117⟩
Article dans une revue
hal-01952201
v1
|
|
18F-F13640 preclinical evaluation in rodent, cat and primate as a 5-HT1A receptor agonist for PET neuroimaging
Benjamin Vidal
,
Sylvain Fieux
,
Matthieu Colom
,
Thierry Billard
,
Caroline Bouillot
et al.
Article dans une revue
hal-02107028
v1
|
|
Ozone Atmospheric Pollution and Alzheimer’s Disease: From Epidemiological Facts to Molecular Mechanisms
Marine L. Croze
,
Luc Zimmer
Article dans une revue
hal-01785212
v1
|
|
Quantitative longitudinal imaging of activated microglia as a marker of inflammation in the pilocarpine rat model of epilepsy using [ 11 C]-( R )-PK11195 PET and MRI
Josiane Yankam Njiwa
,
Nicolas Costes
,
Caroline Bouillot
,
Sandrine Bouvard
,
Sylvain Fieux
et al.
Article dans une revue
hal-01571316
v1
|
|
Hippocampal 5-HT 1A receptor expression changes in prodromal stages of Alzheimer's disease: Beneficial or deleterious?
Mathieu Verdurand
,
Luc Zimmer
Article dans une revue
hal-01689706
v1
|
|
Characterization and Reliability of [18F]2FNQ1P in Cynomolgus Monkeys as a PET Radiotracer for Serotonin 5-HT6 Receptors
Véronique Sgambato-Faure
,
Thierry Billard
,
Elise Metereau
,
Sandra Duperrier
,
Sylvain Fieux
et al.
Article dans une revue
hal-01689720
v1
|
|
Activity in the rat olfactory cortex is correlated with behavioral response to odor: a microPET study
Philippe Litaudon
,
Caroline Bouillot
,
Luc Zimmer
,
Nicolas Costes
,
Nadine Ravel
Article dans une revue
hal-03773095
v1
|
|
[11C]PF-3274167 as a PET radiotracer of oxytocin receptors: Radiosynthesis and evaluation in rat brain
Benjamin Vidal
,
Iuliia Karpenko
,
François Liger
,
Sylvain Fieux
,
Caroline Bouillot
et al.
Article dans une revue
hal-01689748
v1
|
|
Contribution of Clinical Neuroimaging to the Understanding of the Pharmacology of Methylphenidate
Luc Zimmer
Article dans une revue
hal-01689783
v1
|
|
Differential effects of amyloid-beta 1–40 and 1–42 fibrils on 5-HT1A serotonin receptors in rat brain
Mathieu Verdurand
,
Fabien Chauveau
,
Alexia Daoust
,
Anne-Laure Morel
,
Frédéric Bonnefoi
et al.
Article dans une revue
hal-01291764
v1
|
|
Marmoset Serotonin 5-HT 1A Receptor Mapping with a Biased Agonist PET Probe 18 F-F13714: Comparison with an Antagonist Tracer 18 F-MPPF in Awake and Anesthetized States
Chihiro Yokoyama
,
Aya Mawatari
,
Akihiro Kawasaki
,
Chiho Takeda
,
Kayo Onoe
et al.
Article dans une revue
hal-01488155
v1
|
|
Imaging Dopamine and Serotonin Systems on MPTP Monkeys: A Longitudinal PET Investigation of Compensatory Mechanisms
Bénédicte Ballanger
,
Maude Beaudoin-Gobert
,
Sara Neumane
,
Justine Epinat
,
Elise Metereau
et al.
Article dans une revue
hal-01571297
v1
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Selective serotonin 5-HT1A receptor biased agonists elicit distinct brain activation patterns: a pharmacoMRI study
G. Becker
,
R. Bolbos
,
N. Costes
,
J. Redouté
,
A. Newman-Tancredi
et al.
Article dans une revue
hal-01488190
v1
|
|
Pharmacological agonists for more-targeted CNS radio-pharmaceuticals
Luc Zimmer
Article dans une revue
hal-01488034
v1
|
|
A microPET comparison of the effects of etifoxine and diazepam on [11C]flumazenil uptake in rat brains
Caroline Bouillot
,
Frédéric Bonnefoi
,
François Liger
,
Luc Zimmer
Article dans une revue
hal-01264750
v1
|
|
PIXSIC: A Wireless Intracerebral Radiosensitive Probe in Freely Moving Rats
Laure Balasse
,
Julia Maerk
,
Frédéric Pain
,
Aurélie Genoux
,
Sylvain Fieux
et al.
Article dans une revue
in2p3-01235714
v1
|
|
Selective trifluoromethylthiolation of heteroaromatic sp2 C-H bonds with the 2nd generation of trifluoromethanesulfenamide reagent
Alazet Sébastien
,
Zimmer Luc
,
Billard Thierry
Journal of Fluorine Chemistry, 2015, 171, pp.78-81
Article dans une revue
hal-01152905
v1
|
|
PIXSIC, a Pixelated β(+)-Sensitive Probe for Radiopharmacological Investigations in Rat Brain: Binding Studies with [(18)F]MPPF.
Laure Balasse
,
Julia Maerk
,
Frédéric Pain
,
Aurélie Genoux
,
Sylvain Fieux
et al.
Article dans une revue
hal-01105052
v1
|
|
Preclinical evaluation of [18F]2FNQ1P as the first fluorinated serotonin 5-HT6 radioligand for PET imaging
Guillaume Becker
,
Julie Colomb
,
Véronique Sgambato-Faure
,
Léon Tremblay
,
Thierry Billard
et al.
Article dans une revue
hal-01128421
v1
|
|
Electrophilic trifluoromethylthiolation of carbonyl compounds
Alazet Sébastien
,
Zimmer Luc
,
Billard Thierry
Chemistry - A European Journal, 2014, 20 (28), pp.8589-8593
Article dans une revue
hal-01151171
v1
|
|
A Multi-Atlas Based Method for Automated Anatomical Rat Brain MRI Segmentation and Extraction of PET Activity
Sophie Lancelot
,
Roxane Roche
,
Afifa Slimen
,
Caroline Bouillot
,
Élise Levigoureux
et al.
Article dans une revue
hal-01128452
v1
|
|
Binding of the PET Radiotracer [18F]BF227 Does not Reflect the Presence of Alpha-Synuclein Aggregates in Transgenic Mice
Élise Levigoureux
,
Sophie Lancelot
,
Caroline Bouillot
,
Fabien Chauveau
,
Mathieu Verdurand
et al.
Article dans une revue
hal-01128444
v1
|
|
A Postmortem Study to Compare Agonist and Antagonist 5-HT1A Receptor-binding Sites in Alzheimer's Disease
Guillaume Becker
,
Nathalie Streichenberger
,
Thierry Billard
,
Adrian Newman-Tancredi
,
Luc Zimmer
Article dans une revue
hal-01128433
v1
|
|
Syntheses, radiolabelings and in vitro evaluations of fluorinated PET radioligands of 5-HT6 serotoninergic receptors.
Julie Colomb
,
Guillaume Becker
,
Sylvain Fieux
,
Luc Zimmer
,
And Thierry Billard
Journal of Medicinal Chemistry, 2014, 57, pp.3884-90
Article dans une revue
hal-01309560
v1
|
|
PET radiotracers for molecular imaging of serotonin 5-HT1A receptors
T. Billard
,
D. Le Bars
,
L. Zimmer
Article dans une revue
istex
hal-00947714
v1
|
|
Ultra high performance liquid chromatography as a tool for the discovery and the analysis of biomarkers of diseases: A review
L. Denoroy
,
L. Zimmer
,
B. Renaud
,
S. Parrot
Article dans une revue
istex
hal-00847427
v1
|
|
Base-Catalyzed Electrophilic Trifluoromethylthiolation of Terminal Alkynes
S. Alazet
,
L. Zimmer
,
T. Billard
Article dans une revue
hal-00948085
v1
|
|
A wireless beta-microprobe based on pixelated silicon for in vivo brain studies in freely moving rats
Julia Maerk
,
Didier Benoit
,
Laure Balasse
,
Mathieu Benoit
,
Jean-Claude Clémens
et al.
Article dans une revue
in2p3-00837658
v1
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Radiosynthesis and in vivo evaluation of fluorinated huprine derivates as PET radiotracers of acetylcholinesterase
Emilie da Costa Branquinho
,
Guillaume Becker
,
Cédric Bouteiller
,
Ludovic Jean
,
Pierre-Yves Renard
et al.
Article dans une revue
istex
hal-00847401
v1
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Outcome of Poor-Grade Subarachnoid Hemorrhage as Determined by Biomarkers of Glucose Cerebral Metabolism
G.K. Barcelos
,
Y. Tholance
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S. Grousson
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B. Renaud
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A. Perret-Liaudet
et al.
Article dans une revue
hal-00847412
v1
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Current status of positron emission tomography radiotracers for serotonin receptors in humans
L. Zimmer
,
D. Le Bars
Journal of Labelled Compounds and Radiopharmaceuticals, 2013, 56 (3-4), pp.105-113. ⟨10.1002/jlcr.3001⟩
Article dans une revue
istex
hal-00828326
v1
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Enhanced Anxiety Observed in Cocaine Withdrawn Rats Is Associated with Altered Reactivity of the Dorsomedial Prefrontal Cortex
Cynthia El Hage
,
Virginie Rappeneau
,
Adeline Etiévant
,
Anne-Laure Morel
,
Hélène Scarna
et al.
Article dans une revue
hal-03630188
v1
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MicroPET imaging of 5-HT1A receptors in rat brain: a test-retest [18F]MPPF study
N. Aznavour
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C. Benkelfat
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P. Gravel
,
A. Aliaga
,
P. Rosa-Neto
et al.
Article dans une revue
istex
hal-00847462
v1
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Internalization of serotonin 5‐HT 1A autoreceptors as an imaging biomarker of antidepressant response
Luc Zimmer
,
Laurent Descarries
Wiley Interdisciplinary Reviews: Membrane Transport and Signaling, 2012, 1 (3), pp.239-245. ⟨10.1002/wmts.11⟩
Article dans une revue
hal-00797786
v1
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Behaviour of a genetic mouse model of depression in the learned helplessness paradigm
Laure Bougarel
,
Jérôme Guitton
,
Luc Zimmer
,
Jean-Marie Vaugeois
,
Malika El Yacoubi
Article dans une revue
istex
hal-02185484
v1
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Genetic association between helpless trait and depression-related phenotypes: evidence from crossbreeding studies with H/Rouen and NH/Rouen mice.
Malika El Yacoubi
,
Daniela Popa
,
Benoît Martin
,
Luc Zimmer
,
Michel Hamon
et al.
Article dans une revue
hal-00904261
v1
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Genetic Inactivation of Prokineticin Receptor-1 Leads to Heart and Kidney Disorders
Mounia Boulberdaa
,
Gulen Turkeri
,
Kyoji Urayama
,
Mojdeh Dormishian
,
Cécilia Szatkowski
et al.
Article dans une revue
hal-02391087
v1
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[18F]F15599, a novel 5-HT1A receptor agonist, as a radioligand for PET neuroimaging.
Laëtitia Lemoine
,
Mathieu Verdurand
,
Bernard Vacher
,
Elodie Blanc
,
Didier Le Bars
et al.
Article dans une revue
istex
hal-00475580
v1
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Effects of amyloid-beta peptides on the serotoninergic 5-HT(1A) receptors in the rat hippocampus.
Mathieu Verdurand
,
Anne Bérod
,
Didier Le Bars
,
Luc Zimmer
Article dans une revue
istex
hal-00397792
v1
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F15063, a potential antipsychotic with dopamine D2/D3 receptor antagonist, 5-HT1A receptor agonist and dopamine D4 receptor partial agonist properties: Influence on neuronal firing and neurotransmitter release
Marie-Bernadette Assié
,
Ouissame Mnie-Filali
,
Véronique Ravailhe
,
Christelle Benas
,
Marc Marien
et al.
Article dans une revue
istex
hal-04303724
v1
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A distinct [18F]MPPF PET profile in amnestic mild cognitive impairment compared to mild Alzheimer's disease
L. Truchot
,
N. Costes
,
L. Zimmer
,
B. Laurent
,
D. Le Bars
et al.
NeuroImage, 2008, 15 (40), pp.(1251-6)
Article dans une revue
hal-00443483
v1
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The potential of a radiosensitive intracerebral probe to monitor 18F-MPPF binding in mouse hippocampus in vivo
A. Desbrée
,
M. Verdurand
,
J. Godart
,
André Dubois
,
R. Mastrippolito
et al.
Article dans une revue
hal-03002294
v1
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Simultaneous in vivo magnetic resonance imaging and radioactive measurements with the β-MicroProbe
A. Desbrée
,
L. Rbah
,
J.-B. Langlois
,
D. Grenier
,
R. Mastrippolito
et al.
Article dans une revue
istex
hal-03015570
v1
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Up-regulation of hippocampal serotonin metabolism in mild cognitive impairment
L. Truchot
,
N. Costes
,
L. Zimmer
,
B. Laurent
,
D. Le Bars
et al.
Neurology, 2007, 69 (10), pp.(1012-7)
Article dans une revue
hal-00443482
v1
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Raytest ClearPET, a new generation small animal PET scanner
Pablo Sempere Roldan
,
Emmanuel Chereul
,
Oliver Dietzel
,
Luc Magnier
,
Christian Pautrot
et al.
Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 2007, 571 (1-2), pp.498-501. ⟨10.1016/j.nima.2006.10.143⟩
Article dans une revue
istex
hal-00443461
v1
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Simultaneous in vivo Magnetic Resonance Imaging and Radioactive Measurements by the B-MicroProbe
A. Desbrée
,
L. Rbah
,
J. B. Langlois
,
D. Grenier
,
R. Mastrippolito
et al.
European Journal of Nuclear Medicine and Molecular Imaging, 2007, 34 (11), pp.1868-72
Article dans une revue
hal-00443228
v1
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A new multimodality system for quantitative in vivo studies in small animals: combination of nuclear magnetic resonance and the radiosensitive beta-MicroProbe
E. A. Desbré
,
Frederic Pain
,
H. Gurden
,
L. Pinot
,
D. Grenier
et al.
IEEE Transactions on Nuclear Science, 2005, 52 (5), pp.1281-1287
Article dans une revue
hal-00443227
v1
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A new multimodality system for quantitative in vivo studies in small animals: combination of nuclear magnetic resonance and the radiosensitive$\beta$-MicroProbe
A. Desbree
,
Frederic Pain
,
H. Gurden
,
L. Pinot
,
D. Grenier
et al.
Article dans une revue
in2p3-00025341
v1
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The ANIMAGE project: a multimodal imaging platform for small animal research
D. Sappey-Marinier
,
O. Beuf
,
C. Billotey
,
E. Chereul
,
J. Dupuy
et al.
Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 2004, 527, pp.117-123. ⟨10.1016/j.nima.2004.03.092⟩
Article dans une revue
istex
hal-01883295
v1
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Combining the radiosensitive Beta MicroProbe to Nuclear Magnetic Resonance: theoretical approach for in vivo studies in small animals
A. Desbrée
,
Frederic Pain
,
H. Gurden
,
L. Zimmer
,
L. Pinot
et al.
Article dans une revue
istex
in2p3-00025780
v1
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|
Displacement of the PET ligand18F-MPPF by the electrically evoked serotonin release in the rat hippocampus
Latifa Rbah
,
Vincent Leviel
,
Luc Zimmer
Article dans une revue
istex
inserm-02437128
v1
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Neither the density nor function of striatal dopamine transporters were influenced by chronic n-3 polyunsaturated fatty acid deficiency in rodents
Ercem Kodas
,
Guylène Page
,
Luc Zimmer
,
Sylvie Vancassel
,
Denis Guilloteau
et al.
Article dans une revue
istex
hal-02675958
v1
|
|
The potential of the β-Microprobe, an intracerebral radiosensitive probe, to monitor the [18F]MPPF binding in the rat dorsal raphe nucleus
L. Zimmer
,
Frederic Pain
,
G. Mauger
,
A. Plenevaux
,
D. Le Bars
et al.
Article dans une revue
istex
in2p3-00023833
v1
|
|
SIC, an intracerebral beta(+)-range-sensitive probe for radiopharmacology investigations in small laboratory animals: Binding studies with C-11-raclopride
L. Zimmer
,
W. Hassoun
,
Frederic Pain
,
F. Bonnefoi
,
P. Laniece
et al.
Journal of Nuclear Medicine, 2002, 43, pp.227-233
Article dans une revue
in2p3-00013611
v1
|
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The dopamine mesocorticolimbic pathway is affected by deficiency in n-3 polyunsaturated fatty acids
Luc Zimmer
,
Sylvie Vancassel
,
Sylvain Cantagrel
,
Patrick Breton
,
Séraphin Delamanche
et al.
Article dans une revue
hal-02675380
v1
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Polyunsaturated fatty acids and cerebral function: focus on monoaminergic neurotransmission
S. Chalon
,
Sylvie Vancassel
,
L. Zimmer
,
D. Guilloteau
,
Georges Durand
Article dans une revue
istex
hal-02683336
v1
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Modification of dopamine neurotransmission in the nucleus accumbens of rats deficient in n-3 polyunsaturated fatty acids
Luc Zimmer
,
Sylvie Vancassel
,
Georges Durand
,
Denis Guilloteau
,
Sylvie Bodard
et al.
Journal of Lipid Research, 2000, 41 (1), 9 p
Article dans une revue
hal-02697599
v1
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Chronic n-3 polyunsaturated fatty acid deficiency alters dopamine vesicle density in the rat frontal cortex
L. Zimmer
,
Serge Delpal
,
D. Guilloteau
,
Josiane Aïoun
,
G. Durand
et al.
Neuroscience Letters, 2000, 284, pp.25-28
Article dans une revue
hal-02696603
v1
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Chronic n-3 polyunsaturated fatty acid diet-deficiency acts on dopamine metabolism in the rat frontal cortex: a microdialysis study
L. Zimmer
,
S. Hembert
,
G. Durand
,
Pauline Breton
,
D. Guilloteau
et al.
Neuroscience Letters, 1998, 240, pp.177-181
Article dans une revue
hal-02697597
v1
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