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Luc ZIMMER

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A consensus protocol for functional connectivity analysis in the rat brain

Joanes Grandjean , Gabriel Desrosiers-Gregoire , Cynthia Anckaerts , Diego Angeles-Valdez , Fadi Ayad
Nature Neuroscience, 2023, 26 (4), pp.673-681. ⟨10.1038/s41593-023-01286-8⟩
Article dans une revue hal-04268925v1

A revisited version of the disputatio for pharmacological training: An educational study

Louise Carton , Romain Bordy , Perle Totoson , Edouard-Jules Laforgue , Jean-Marc Pelerin
Article dans une revue hal-04357024v1
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[18F]F13640: a selective agonist PET radiopharmaceutical for imaging functional 5-HT1A receptors in humans

Pierre Courault , Sophie Lancelot , Nicolas Costes , Matthieu Colom , Didier Le Bars
European Journal of Nuclear Medicine and Molecular Imaging, 2023, 50 (6), pp.1651-1664. ⟨10.1007/s00259-022-06103-1⟩
Article dans une revue hal-04528816v1

Positron Emission Tomography for the Discovery of New Drugs in Psychiatry

Luc Zimmer
ACS Chemical Neuroscience, 2023, 14 (4), pp.524-526. ⟨10.1021/acschemneuro.3c00036⟩
Article dans une revue hal-04528842v1
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Anti-CD20 therapies in multiple sclerosis: From pathology to the clinic

Jérôme de Sèze , Elisabeth Maillart , Antoine Gueguen , David A. A. Laplaud , Laure Michel
Frontiers in Immunology, 2023, 14, pp.1004795. ⟨10.3389/fimmu.2023.1004795⟩
Article dans une revue hal-04086889v1

Single subanesthetic dose of ketamine produces delayed impact on brain [18F]FDG PET imaging and metabolic connectivity in rats

Sarah Chaib , Caroline Bouillot , Sandrine Bouvard , Benjamin Vidal , Luc Zimmer
Frontiers in Neuroscience, 2023, 17, pp.1213941. ⟨10.3389/fnins.2023.1213941⟩
Article dans une revue hal-04528862v1
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PET metabolic imaging of time-dependent reorganization of olfactory cued fear memory networks in rats

Anne-Marie Mouly , Caroline Bouillot , Nicolas Costes , Luc Zimmer , Nadine Ravel
Cerebral Cortex, 2022, 32 (13), pp.2717-2728. ⟨10.1093/cercor/bhab376⟩
Article dans une revue hal-03772913v1
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Different alterations of agonist and antagonist binding to 5-HT1A receptor in a rat model of Parkinson's disease and levodopa-induced dyskinesia : a microPET study

Benjamin Vidal , Elise Levigoureux , Sarah Chaib , Caroline Bouillot , Thierry Billard
Journal of Parkinson's disease, 2021, 11 (3), pp.1257-1269. ⟨10.3233/JPD-212580⟩
Article dans une revue hal-03407557v1
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[18F]F13640, a 5-HT1A Receptor Radiopharmaceutical Sensitive to Brain Serotonin Fluctuations

Matthieu Colom , Benjamin Vidal , Sylvain Fieux , Jérôme Redoute , Nicolas Costes
Frontiers in Neuroscience, 2021, 15, ⟨10.3389/fnins.2021.622423⟩
Article dans une revue hal-03407570v1
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PET metabolic imaging of time-dependent reorganization of olfactory cued fear memory networks in rats

Anne-Marie Mouly , Caroline Bouillot , Nicolas Costes , Luc Zimmer , Nadine Ravel
Cerebral Cortex, In press
Article dans une revue hal-03358716v1

Towards in vivo imaging of functionally active 5-HT1A receptors in schizophrenia: concepts and challenges

Oriane Razakarivony , Adrian Newman-Tancredi , Luc Zimmer
Translational Psychiatry, 2021, 11 (1), ⟨10.1038/s41398-020-01119-3⟩
Article dans une revue hal-03160747v1
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Clinical research in psychopharmacology, the current situation and its perspectives. A conversation with Pierre-Michel Llorca

Pierre-Michel Llorca , Luc Zimmer
Thérapie, 2021, 76 (2), pp.67-70. ⟨10.1016/j.therap.2020.12.003⟩
Article dans une revue hal-03549103v1

Innovative approaches in CNS drug discovery

Mathieu Charvériat , Vincent Lafon , Franck Mouthon , Luc Zimmer
Alternative and Complementary Therapies, 2021, 76 (2), pp.101-109. ⟨10.1016/j.therap.2020.12.006⟩
Article dans une revue hal-03160773v1

Functional ultrasound imaging to study brain dynamics: Application of pharmaco-fUS to atomoxetine

Benjamin Vidal , Marine Droguerre , Ludovic Venet , Luc Zimmer , Marco Valdebenito
Neuropharmacology, 2020, 179, pp.108273. ⟨10.1016/j.neuropharm.2020.108273⟩
Article dans une revue hal-03160725v1

Preclinical validation of [18F]2FNQ1P as a specific PET radiotracer of 5-HT6 receptors in rat, pig, non-human primate and human brain tissue

Stéphane Emery , Sylvain Fieux , Benjamin Vidal , Pierre Courault , Sandrine Bouvard
Nuclear Medicine and Biology, 2020, 82-83, pp.57-63. ⟨10.1016/j.nucmedbio.2020.01.006⟩
Article dans une revue hal-03035781v1

Pharmaco-fUS for Characterizing Drugs for Alzheimer’s Disease – The Case of THN201, a Drug Combination of Donepezil Plus Mefloquine

Benjamin Vidal , Marine Droguerre , Marco Valdebenito , Luc Zimmer , Michel Hamon
Frontiers in Neuroscience, 2020, 14, pp.835. ⟨10.3389/fnins.2020.00835⟩
Article dans une revue hal-03160675v1
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Bayesian Estimation of the ntPET Model in Single-Scan Competition PET Studies

Zacharie Irace , Inés Mérida , Jérôme Redouté , Clara Fonteneau , Marie-Françoise Suaud-Chagny
Frontiers in Physiology, 2020, 11, pp.498. ⟨10.3389/fphys.2020.00498⟩
Article dans une revue hal-03160651v1
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Change in Expression of 5-HT6 Receptor at Different Stages of Alzheimer’s Disease: A Postmortem Study with the PET Radiopharmaceutical [18F]2FNQ1P

Pierre Courault , Stéphane Emery , Sandrine Bouvard , François Liger , Fabien Chauveau
Journal of Alzheimer's Disease, 2020, 75 (4), pp.1329-1338. ⟨10.3233/JAD-191278⟩
Article dans une revue hal-03035778v1

18F-F13640 PET imaging of functional receptors in humans

Matthieu Colom , Nicolas Costes , Jerome Redoute , Frédéric Dailler , Florent Gobert
European Journal of Nuclear Medicine and Molecular Imaging, 2020, 47 (1), pp.220-221. ⟨10.1007/s00259-019-04473-7⟩
Article dans une revue hal-02305453v1
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Pharmacological MRI to investigate the functional selectivity of 5-HT1A receptor biased agonists

Benjamin Vidal , Radu Bolbos , Jérôme Redouté , Jean-Baptiste Langlois , Nicolas Costes
Neuropharmacology, 2020, 172, pp.107867 -. ⟨10.1016/j.neuropharm.2019.107867⟩
Article dans une revue hal-03490240v1
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Sécurisation de la prise en charge médicamenteuse des patients sous antipsychotiques : impact de la collaboration médico-pharmaceutique à la Maison d’Arrêt de Lyon-Corbas

C. Picard , L. Lalande , C. Bertin , C. Abel-Coindoz , A. Mauchauffée
L'Encéphale, 2019, 45, pp.482 - 487. ⟨10.1016/j.encep.2019.05.008⟩
Article dans une revue hal-03488422v1
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Evaluation of Myelin Radiotracers in the Lysolecithin Rat Model of Focal Demyelination: Beware of Pitfalls!

Min Zhang , Gaëlle Hugon , Caroline Bouillot , Radu Bolbos , Jean-Baptiste Langlois
Contrast Media and Molecular Imaging, 2019, 2019, pp.9294586. ⟨10.1155/2019/9294586⟩
Article dans une revue hal-02278818v1
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MAPSSIC, a Novel CMOS Intracerebral Positrons Probe for Deep Brain Imaging in Awake and Freely Moving Rats: A Monte Carlo Study

L. Ammour , J. Heymes , M. Bautista , S. Fieux , F. Gensolen
IEEE Transactions on Radiation and Plasma Medical Sciences, 2019, 3 (3), pp.302-314. ⟨10.1109/TRPMS.2018.2881301⟩
Article dans une revue hal-02165345v1

Serotonin 5-HT 1A Receptor Biased Agonists Induce Different Cerebral Metabolic Responses: A [ 18 F]-Fluorodesoxyglucose Positron Emission Tomography Study in Conscious and Anesthetized Rats

Elise Levigoureux , Benjamin Vidal , Sylvain Fieux , Caroline Bouillot , Stéphane Emery
ACS Chemical Neuroscience, 2019, 10 (7), pp.3108-3119. ⟨10.1021/acschemneuro.8b00584⟩
Article dans une revue hal-02305418v1
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PET imaging of the influence of physiological and pathological α‐synuclein on dopaminergic and serotonergic neurotransmission in mouse models

Elise Levigoureux , Caroline Bouillot , Thierry Baron , Luc Zimmer , Sophie Lancelot
CNS Neuroscience & Therapeutics, 2019, 25 (1), pp.57-68. ⟨10.1111/cns.12978⟩
Article dans une revue hal-04112106v1

Is there a Role for Agonist Radiopharmaceuticals in PET Neuroimaging?

Matthieu Colom , Benjamin Vidal , Zimmer Luc
Frontiers in Molecular Neuroscience, 2019, 12, pp.255. ⟨10.3389/fnmol.2019.00255⟩
Article dans une revue hal-02310324v1
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Meta-analysis in metastatic uveal melanoma to determine progression free and overall survival benchmarks: an international rare cancers initiative (IRCI) ocular melanoma study

L Khoja , E. G. Atenafu , S Suciu , S Leyvraz , T Sato
Annals of Oncology, 2019, 30 (8), pp.1370-1380. ⟨10.1093/annonc/mdz176⟩
Article dans une revue hal-02466385v1

Evaluation of [ 18 F]2FP3 in pigs and non-human primates

Hanne Hansen , Cristian Constantinescu , Olivier Barret , Matthias Herth , Janus Magnussen
Journal of Labelled Compounds and Radiopharmaceuticals, 2019, 62 (1), pp.34-42. ⟨10.1002/jlcr.3692⟩
Article dans une revue hal-02109621v1
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Amyloid-beta radiotracer [ 18 F]BF-227 does not bind to cytoplasmic glial inclusions of post-mortem Multiple System Atrophy brain tissue

Mathieu Verdurand , Elise Levigoureux , Sophie Lancelot , Waël Zeinyeh , Thierry Billard
Contrast Media and Molecular Imaging, 2018, 2018, ⟨10.1155/2018/9165458⟩
Article dans une revue hal-01691091v1

In Silico, in Vitro, and in Vivo Evaluation of New Candidates for α-Synuclein PET Imaging

Mathieu Verdurand , Elise Levigoureux , Wael Zeinyeh , Laurent Berthier , Meriem Mendjel-Herda
Molecular Pharmaceutics, 2018, 15 (8), pp.3153-3166
Article dans une revue hal-01955442v1

18F-F13640 preclinical evaluation in rodent, cat and primate as a 5-HT1A receptor agonist for PET neuroimaging

Benjamin Vidal , Sylvain Fieux , Matthieu Colom , Thierry Billard , Caroline Bouillot
Brain Structure and Function, 2018, 223 (6), pp.2973-2988. ⟨10.1007/s00429-018-1672-7⟩
Article dans une revue hal-02107028v1
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Implantable CMOS pixel sensor for positron imaging in rat brain

J. Heymes , L. Ammour , M. Bautista , G. Bertolone , A. Dorokhov
Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 2018, 911, pp.19-24. ⟨10.1016/j.nima.2018.09.117⟩
Article dans une revue hal-01952201v1

In vivo biased agonism at 5-HT1A receptors: characterisation by simultaneous PET/MR imaging

Benjamin Vidal , Sylvain Fieux , Jerome Redoute , Marjorie Villien , Frédéric Bonnefoi
Neuropsychopharmacology, 2018, 43 (11), pp.2310 - 2319. ⟨10.1038/s41386-018-0145-2⟩
Article dans une revue hal-01917722v1

Ozone Atmospheric Pollution and Alzheimer’s Disease: From Epidemiological Facts to Molecular Mechanisms

Marine L. Croze , Luc Zimmer
Journal of Alzheimer's Disease, 2018, 62 (2), pp.503 - 522. ⟨10.3233/JAD-170857⟩
Article dans une revue hal-01785212v1

Activity in the rat olfactory cortex is correlated with behavioral response to odor: a microPET study

Philippe Litaudon , Caroline Bouillot , Luc Zimmer , Nicolas Costes , Nadine Ravel
Brain Structure and Function, 2017, 222 (1), pp.577-586. ⟨10.1007/s00429-016-1235-8⟩
Article dans une revue hal-03772857v1

Hippocampal 5-HT 1A receptor expression changes in prodromal stages of Alzheimer's disease: Beneficial or deleterious?

Mathieu Verdurand , Luc Zimmer
Neuropharmacology, 2017, 123, pp.446 - 454. ⟨10.1016/j.neuropharm.2017.06.021⟩
Article dans une revue hal-01689706v1
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Quantitative longitudinal imaging of activated microglia as a marker of inflammation in the pilocarpine rat model of epilepsy using [ 11 C]-( R )-PK11195 PET and MRI

J. Yankam-Njiwa , N. Costes , C. Bouillot , S. Bouvard , S. Fieux
Journal of Cerebral Blood Flow and Metabolism, 2017, 37 (4), pp.1251 - 1263. ⟨10.1177/0271678X16653615⟩
Article dans une revue hal-01571316v1

Contribution of Clinical Neuroimaging to the Understanding of the Pharmacology of Methylphenidate

Luc Zimmer
Trends in Pharmacological Sciences, 2017, 38 (7), pp.608 - 620. ⟨10.1016/j.tips.2017.04.001⟩
Article dans une revue hal-01689783v1
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Characterization and Reliability of [18F]2FNQ1P in Cynomolgus Monkeys as a PET Radiotracer for Serotonin 5-HT6 Receptors

Véronique Sgambato-Faure , Thierry Billard , Elise Metereau , Sandra Duperrier , Sylvain Fieux
Frontiers in Pharmacology, 2017, 8, pp.471. ⟨10.3389/fphar.2017.00471⟩
Article dans une revue hal-01689720v1

[ 11 C]PF-3274167 as a PET radiotracer of oxytocin receptors: Radiosynthesis and evaluation in rat brain

Benjamin Vidal , Iuliia Karpenko , François Liger , Sylvain Fieux , Caroline Bouillot
Nuclear Medicine and Biology, 2017, 55, pp.1 - 6. ⟨10.1016/j.nucmedbio.2017.07.008⟩
Article dans une revue hal-01689748v1
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Activity in the rat olfactory cortex is correlated with behavioral response to odor: a microPET study

Philippe Litaudon , Caroline Bouillot , Luc Zimmer , Nicolas Costes , Nadine Ravel
Brain Structure and Function, 2017, 222 (1), pp.577-586. ⟨10.1007/s00429-016-1235-8⟩
Article dans une revue hal-03773095v1
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The in Vitro Actions of Loxapine on Dopaminergic and Serotonergic Receptors. Time to Consider Atypical Classification of This Antipsychotic Drug?

Florian Ferreri , Dominique Drapier , Emmanuelle Baloche , Mehemed Ouzid , Luc Zimmer
International Journal of Neuropsychopharmacology, 2017, 21 (4), pp.355-360. ⟨10.1093/ijnp/pyx102⟩
Article dans une revue hal-01696767v1

Activity in the rat olfactory cortex is correlated with behavioral response to odor: a microPET study

Philippe Litaudon , Caroline Bouillot , Luc Zimmer , Nicolas Costes , Nadine Ravel
Brain Structure and Function, 2017, 222 (1), pp.577-586. ⟨10.1007/s00429-016-1235-8⟩
Article dans une revue hal-02104688v1
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Marmoset Serotonin 5-HT 1A Receptor Mapping with a Biased Agonist PET Probe 18 F-F13714: Comparison with an Antagonist Tracer 18 F-MPPF in Awake and Anesthetized States

Chihiro Yokoyama , Aya Mawatari , Akihiro Kawasaki , Chiho Takeda , Kayo Onoe
International Journal of Neuropsychopharmacology, 2016, 19 (12), pp.1 - 12. ⟨10.1093/ijnp/pyw079⟩
Article dans une revue hal-01488155v1

A microPET comparison of the effects of etifoxine and diazepam on [11C]flumazenil uptake in rat brains

Caroline Bouillot , Frédéric Bonnefoi , François Liger , Luc Zimmer
Neuroscience Letters, 2016, 612, pp.74-79. ⟨10.1016/j.neulet.2015.11.042⟩
Article dans une revue hal-01264750v1
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Imaging Dopamine and Serotonin Systems on MPTP Monkeys: A Longitudinal PET Investigation of Compensatory Mechanisms

Benedicte Ballanger , Maude Beaudoin-Gobert , Sara Neumane , Justine Epinat , Elise Météreau
Journal of Neuroscience, 2016, 36 (5), pp.1577-1589. ⟨10.1523/JNEUROSCI.2010-15.2016⟩
Article dans une revue hal-02115078v1
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Pharmacological agonists for more-targeted CNS radio-pharmaceuticals

Luc Zimmer
Oncotarget, 2016, 7 (49), pp.80111 - 80112. ⟨10.18632/oncotarget.13418⟩
Article dans une revue hal-01488034v1
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Imaging Dopamine and Serotonin Systems on MPTP Monkeys: A Longitudinal PET Investigation of Compensatory Mechanisms

Bénédicte Ballanger , Maude Beaudoin-Gobert , Sara Neumane , Justine Epinat , Elise Metereau
Journal of Neuroscience, 2016, 36 (5), pp.1577 - 1589. ⟨10.1523/JNEUROSCI.2010-15.2016⟩
Article dans une revue hal-01571297v1
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Selective serotonin 5-HT1A receptor biased agonists elicit distinct brain activation patterns: a pharmacoMRI study

G. Becker , R. Bolbos , N. Costes , J. Redouté , A. Newman-Tancredi
Scientific Reports, 2016, 6 (1), pp.26633. ⟨10.1038/srep26633⟩
Article dans une revue hal-01488190v1

Differential effects of amyloid-beta 1–40 and 1–42 fibrils on 5-HT1A serotonin receptors in rat brain

Mathieu Verdurand , Fabien Chauveau , Alexia Daoust Daoust , Anne-Laure Morel , Frédéric Bonnefoi
Neurobiology of Aging, 2016, 40, pp.11-21. ⟨10.1016/j.neurobiolaging.2015.12.008⟩
Article dans une revue hal-01291764v1

PIXSIC, a Pixelated β(+)-Sensitive Probe for Radiopharmacological Investigations in Rat Brain: Binding Studies with [(18)F]MPPF.

Laure Balasse , Julia Maerk , Frédéric Pain , Aurélie Genoux , Sylvain Fieux
Molecular Imaging and Biology, 2015, 17 (2), pp.163-167. ⟨10.1007/s11307-014-0785-5⟩
Article dans une revue hal-01105052v1

Selective trifluoromethylthiolation of heteroaromatic sp2 C-H bonds with the 2nd generation of trifluoromethanesulfenamide reagent

Alazet Sébastien , Zimmer Luc , Billard Thierry
Journal of Fluorine Chemistry, 2015, 171, pp.78-81
Article dans une revue hal-01152905v1
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PIXSIC: A Wireless Intracerebral Radiosensitive Probe in Freely Moving Rats

Laure Balasse , Julia Maerk , Frédéric Pain , Aurélie Genoux , Sylvain Fieux
Molecular Imaging, 2015, 14 (484–489), ⟨10.2310/7290.2015.00020⟩
Article dans une revue in2p3-01235714v1

Preclinical evaluation of [18F]2FNQ1P as the first fluorinated serotonin 5-HT6 radioligand for PET imaging

Guillaume Becker , Julie Colomb , Véronique Sgambato-Faure , Léon Tremblay , Thierry Billard
European Journal of Nuclear Medicine and Molecular Imaging, 2015, 42 (3), pp.495-502. ⟨10.1007/s00259-014-2936-y⟩
Article dans une revue hal-01128421v1

A Postmortem Study to Compare Agonist and Antagonist 5-HT1A Receptor-binding Sites in Alzheimer's Disease

Guillaume Becker , Nathalie Streichenberger , Thierry Billard , Adrian Newman-Tancredi , Luc Zimmer
CNS Neuroscience and Therapeutics, 2014, 20 (10), pp.930-934. ⟨10.1111/cns.12306⟩
Article dans une revue hal-01128433v1

Binding of the PET Radiotracer [18F]BF227 Does not Reflect the Presence of Alpha-Synuclein Aggregates in Transgenic Mice

Elise Levigoureux , Sophie Lancelot , Caroline Bouillot , Fabien Chauveau , Mathieu Verdurand
Current Alzheimer Research, 2014, 11 (10), pp.955-960. ⟨10.2174/1567205011666141107154201⟩
Article dans une revue hal-01128444v1

Electrophilic trifluoromethylthiolation of carbonyl compounds

Alazet Sébastien , Zimmer Luc , Billard Thierry
Chemistry - A European Journal, 2014, 20 (28), pp.8589-8593
Article dans une revue hal-01151171v1

PET radiotracers for molecular imaging of serotonin 5-HT1A receptors

T. Billard , D. Le Bars , L. Zimmer
Current Medicinal Chemistry, 2014, 21 (1), pp.70-80. ⟨10.2174/09298673113209990215⟩
Article dans une revue hal-00947714v1

Syntheses, radiolabelings and in vitro evaluations of fluorinated PET radioligands of 5-HT6 serotoninergic receptors.

Julie Colomb , Guillaume Becker , Sylvain Fieux , Luc Zimmer , And Thierry Billard
Journal of Medicinal Chemistry, 2014, 57, pp.3884-90
Article dans une revue hal-01309560v1

A Multi-Atlas Based Method for Automated Anatomical Rat Brain MRI Segmentation and Extraction of PET Activity

Sophie Lancelot , Roxane Roche , Afifa Slimen , Caroline Bouillot , Elise Levigoureux
PLoS ONE, 2014, 9 (10), pp.0109113. ⟨10.1371/journal.pone.0109113⟩
Article dans une revue hal-01128452v1

Radiosynthesis and in vivo evaluation of fluorinated huprine derivates as PET radiotracers of acetylcholinesterase

Emilie da Costa Branquinho , Guillaume Becker , Cédric Bouteiller , Ludovic Jean , Pierre-Yves Renard
Nuclear Medicine and Biology, 2013, 40 (4), pp.554-560. ⟨10.1016/j.nucmedbio.2013.02.004⟩
Article dans une revue hal-00847401v1

Outcome of Poor-Grade Subarachnoid Hemorrhage as Determined by Biomarkers of Glucose Cerebral Metabolism

G.K. Barcelos , Y. Tholance , S. Grousson , B. Renaud , A. Perret-Liaudet
Neurocritical Care, 2013, 18 (2), pp.234-244. ⟨10.1007/s12028-012-9810-1⟩
Article dans une revue hal-00847412v1

Ultra high performance liquid chromatography as a tool for the discovery and the analysis of biomarkers of diseases: A review

L. Denoroy , L. Zimmer , B. Renaud , S. Parrot
Journal of Chromatography B - Analytical Technologies in the Biomedical and Life Sciences, 2013, 927, pp.37-53. ⟨10.1016/j.jchromb.2012.12.005⟩
Article dans une revue hal-00847427v1

A wireless beta-microprobe based on pixelated silicon for in vivo brain studies in freely moving rats

Julia Maerk , Didier Benoit , Laure Balasse , Mathieu Benoit , Jean-Claude Clémens
Physics in Medicine and Biology, 2013, 58, pp.4483 - 4500. ⟨10.1088/0031-9155/58/13/4483⟩
Article dans une revue in2p3-00837658v1

Base-Catalyzed Electrophilic Trifluoromethylthiolation of Terminal Alkynes

S. Alazet , L. Zimmer , T. Billard
Angewandte Chemie International Edition, 2013, 52 (41), pp.10814-10817. ⟨10.1002/anie.201305179⟩
Article dans une revue hal-00948085v1

Current status of positron emission tomography radiotracers for serotonin receptors in humans

L. Zimmer , D. Le Bars
Journal of Labelled Compounds and Radiopharmaceuticals, 2013, 56 (3-4), pp.105-113. ⟨10.1002/jlcr.3001⟩
Article dans une revue hal-00828326v1
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Enhanced Anxiety Observed in Cocaine Withdrawn Rats Is Associated with Altered Reactivity of the Dorsomedial Prefrontal Cortex

Cynthia El Hage , Virginie Rappeneau , Adeline Etiévant , Anne-Laure Morel , Hélène Scarna
PLoS ONE, 2012, 7 (8), pp.e43535. ⟨10.1371/journal.pone.0043535⟩
Article dans une revue hal-03630188v1

MicroPET imaging of 5-HT1A receptors in rat brain: a test-retest [18F]MPPF study

N. Aznavour , C. Benkelfat , P. Gravel , A. Aliaga , P. Rosa-Neto
European Journal of Nuclear Medicine and Molecular Imaging, 2012, 36 (1), pp.53-62. ⟨10.1007/s00259-008-0891-1⟩
Article dans une revue hal-00847462v1

Behaviour of a genetic mouse model of depression in the learned helplessness paradigm

Laure Bougarel , Jérôme Guitton , Luc Zimmer , Jean-Marie Vaugeois , Malika El Yacoubi
Psychopharmacology, 2011, 215 (3), pp.595-605. ⟨10.1007/s00213-011-2218-3⟩
Article dans une revue hal-02185484v1

Genetic Inactivation of Prokineticin Receptor-1 Leads to Heart and Kidney Disorders

Mounia Boulberdaa , Gulen Turkeri , Kyoji Urayama , Mojdeh Dormishian , Cécilia Szatkowski
Arteriosclerosis, Thrombosis, and Vascular Biology, 2011, 31 (4), pp.842-850. ⟨10.1161/ATVBAHA.110.222323⟩
Article dans une revue hal-02391087v1

Genetic association between helpless trait and depression-related phenotypes: evidence from crossbreeding studies with H/Rouen and NH/Rouen mice.

Malika El Yacoubi , Daniela Popa , Benoît Martin , Luc Zimmer , Michel Hamon
International Journal of Neuropsychopharmacology, 2011, 15 (3), pp.363-374. ⟨10.1017/S1461145711000605⟩
Article dans une revue hal-00904261v1

[18F]F15599, a novel 5-HT1A receptor agonist, as a radioligand for PET neuroimaging.

Laëtitia Lemoine , Mathieu Verdurand , Bernard Vacher , Elodie Blanc , Didier Le Bars
European Journal of Nuclear Medicine and Molecular Imaging, 2010, 37 (3), pp.594-605. ⟨10.1007/s00259-009-1274-y⟩
Article dans une revue hal-00475580v1

Effects of amyloid-beta peptides on the serotoninergic 5-HT(1A) receptors in the rat hippocampus.

Mathieu Verdurand , Anne Bérod , Didier Le Bars , Luc Zimmer
Neurobiol Aging, 2009, 32 (1), pp.103-114. ⟨10.1016/j.neurobiolaging.2009.01.008⟩
Article dans une revue hal-00397792v1

F15063, a potential antipsychotic with dopamine D2/D3 receptor antagonist, 5-HT1A receptor agonist and dopamine D4 receptor partial agonist properties: Influence on neuronal firing and neurotransmitter release

Marie-Bernadette Assié , Ouissame Mnie-Filali , Véronique Ravailhe , Christelle Benas , Marc Marien
European Journal of Pharmacology, 2009, 607 (1-3), pp.74-83. ⟨10.1016/j.ejphar.2009.02.001⟩
Article dans une revue hal-04303724v1

A distinct [18F]MPPF PET profile in amnestic mild cognitive impairment compared to mild Alzheimer's disease

L. Truchot , N. Costes , L. Zimmer , B. Laurent , D. Le Bars
NeuroImage, 2008, 15 (40), pp.(1251-6)
Article dans une revue hal-00443483v1

The potential of a radiosensitive intracerebral probe to monitor 18F-MPPF binding in mouse hippocampus in vivo

A. Desbrée , M. Verdurand , J. Godart , André Dubois , R. Mastrippolito
Journal of Nuclear Medicine, 2008, 49 (7), pp.1155-1161. ⟨10.2967/jnumed.107.050047⟩
Article dans une revue hal-03002294v1

Up-regulation of hippocampal serotonin metabolism in mild cognitive impairment

L. Truchot , N. Costes , L. Zimmer , B. Laurent , D. Le Bars
Neurology, 2007, 69 (10), pp.(1012-7)
Article dans une revue hal-00443482v1

Simultaneous in vivo magnetic resonance imaging and radioactive measurements with the β-MicroProbe

A. Desbrée , L. Rbah , J.-B. Langlois , D. Grenier , R. Mastrippolito
European Journal of Nuclear Medicine and Molecular Imaging, 2007, 34 (11), pp.1868-1872. ⟨10.1007/s00259-007-0475-5⟩
Article dans une revue hal-03015570v1

Simultaneous in vivo Magnetic Resonance Imaging and Radioactive Measurements by the B-MicroProbe

A. Desbrée , L. Rbah , J. B. Langlois , D. Grenier , R. Mastrippolito
European Journal of Nuclear Medicine and Molecular Imaging, 2007, 34 (11), pp.1868-72
Article dans une revue hal-00443228v1

Raytest ClearPET, a new generation small animal PET scanner

Pablo Sempere Roldan , Emmanuel Chereul , Oliver Dietzel , Luc Magnier , Christian Pautrot
Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 2007, 571 (1-2), pp.498-501. ⟨10.1016/j.nima.2006.10.143⟩
Article dans une revue hal-00443461v1

A new multimodality system for quantitative in vivo studies in small animals: combination of nuclear magnetic resonance and the radiosensitive$\beta$-MicroProbe

A. Desbree , Frederic Pain , H. Gurden , L. Pinot , D. Grenier
IEEE Transactions on Nuclear Science, 2005, 52, pp.1281-1287. ⟨10.1109/TNS.2005.858216⟩
Article dans une revue in2p3-00025341v1

A new multimodality system for quantitative in vivo studies in small animals: combination of nuclear magnetic resonance and the radiosensitive beta-MicroProbe

E. A. Desbré , Frederic Pain , H. Gurden , L. Pinot , D. Grenier
IEEE Transactions on Nuclear Science, 2005, 52 (5), pp.1281-1287
Article dans une revue hal-00443227v1

Combining the radiosensitive Beta MicroProbe to Nuclear Magnetic Resonance: theoretical approach for in vivo studies in small animals

A. Desbrée , Frederic Pain , H. Gurden , L. Zimmer , L. Pinot
Journal of Neuroscience Methods, 2004, 140, pp.47-52. ⟨10.1016/j.jneumeth.2004.03.029⟩
Article dans une revue in2p3-00025780v1

The ANIMAGE project: a multimodal imaging platform for small animal research

D. Sappey-Marinier , O. Beuf , C. Billotey , E. Chereul , J. Dupuy
Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 2004, 527, pp.117-123. ⟨10.1016/j.nima.2004.03.092⟩
Article dans une revue hal-01883295v1

Displacement of the PET ligand18F-MPPF by the electrically evoked serotonin release in the rat hippocampus

Latifa Rbah , Vincent Leviel , Luc Zimmer
Synapse, 2003, 49 (4), pp.239-245. ⟨10.1002/syn.10235⟩
Article dans une revue inserm-02437128v1

The potential of the β-Microprobe, an intracerebral radiosensitive probe, to monitor the [18F]MPPF binding in the rat dorsal raphe nucleus

L. Zimmer , Frederic Pain , G. Mauger , A. Plenevaux , D. Le Bars
European Journal of Nuclear Medicine and Molecular Imaging, 2002, 29, pp.1237-1247. ⟨10.1007/s00259-002-0866-6⟩
Article dans une revue in2p3-00023833v1

Neither the density nor function of striatal dopamine transporters were influenced by chronic n-3 polyunsaturated fatty acid deficiency in rodents

Ercem Kodas , Guylène Page , Luc Zimmer , Sylvie Vancassel , Denis Guilloteau
Neuroscience Letters, 2002, 321 (1-2), pp.95-99. ⟨10.1016/s0304-3940(01)02481-8⟩
Article dans une revue hal-02675958v1

SIC, an intracerebral beta(+)-range-sensitive probe for radiopharmacology investigations in small laboratory animals: Binding studies with C-11-raclopride

L. Zimmer , W. Hassoun , Frederic Pain , F. Bonnefoi , P. Laniece
Journal of Nuclear Medicine, 2002, 43, pp.227-233
Article dans une revue in2p3-00013611v1

The dopamine mesocorticolimbic pathway is affected by deficiency in n-3 polyunsaturated fatty acids

Luc Zimmer , Sylvie Vancassel , Sylvain Cantagrel , Patrick Breton , Séraphin Delamanche
The American Journal of Clinical Nutrition, 2002, 75 (4), pp.662-667. ⟨10.1093/ajcn/75.4.662⟩
Article dans une revue hal-02675380v1

Polyunsaturated fatty acids and cerebral function: focus on monoaminergic neurotransmission

S. Chalon , Sylvie Vancassel , L. Zimmer , D. Guilloteau , Georges Durand
Lipids, 2001, 36 (9), pp.937-44. ⟨10.1007/s11745-001-0804-7⟩
Article dans une revue hal-02683336v1

Chronic n-3 polyunsaturated fatty acid deficiency alters dopamine vesicle density in the rat frontal cortex

L. Zimmer , Serge Delpal , D. Guilloteau , Josiane Aïoun , G. Durand
Neuroscience Letters, 2000, 284, pp.25-28
Article dans une revue hal-02696603v1
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Modification of dopamine neurotransmission in the nucleus accumbens of rats deficient in n-3 polyunsaturated fatty acids

Luc Zimmer , Sylvie Vancassel , Georges Durand , Denis Guilloteau , Sylvie Bodard
Journal of Lipid Research, 2000, 41 (1), 9 p
Article dans une revue hal-02697599v1

Chronic n-3 polyunsaturated fatty acid diet-deficiency acts on dopamine metabolism in the rat frontal cortex: a microdialysis study

L. Zimmer , S. Hembert , G. Durand , Pauline Breton , D. Guilloteau
Neuroscience Letters, 1998, 240, pp.177-181
Article dans une revue hal-02697597v1

MAPSSIC, a beta+ implantable microprobe for neuroimaging of awake and freely moving rats: first sensor characterization and in vivo imaging simulations

S.El Ketara , F Agnese , L Ammour , J Baudot , S Bouvard
2023 IEEE Nuclear Science Symposium (NSS), Medical Imaging Conference (MIC) and Room Temperature Semiconductor Detector (RTSD) Conference (NSS/MIC 2023), Nov 2023, Vancouver, Canada. ⟨10.1109/NSSMICRTSD49126.2023.10338464⟩
Communication dans un congrès hal-04381878v1
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MAPSSIC, a communicating MAPS-based intracerebral positrons probe for deep brain imaging in awake and freely-moving rats

F. Gensolen , L. Ammour , M. Bautista , J. Heymes , S. Fieux
6th International Conference on Advancements in Nuclear Instrumentation Measurement Methods and their Applications, Jun 2019, Protoroz, Slovenia. pp.09002, ⟨10.1051/epjconf/202022509002⟩
Communication dans un congrès hal-02458778v1

STABILITY AND DISASSEMBLY OF ALPHA-SYNUCLEIN FIBRILS

Mathieu Verdurand , Lucile Maziere , Marion Herault , Anthony Fourier , Isabelle Quadrio
13th International Conference on Alzheimer’s & Parkinson’s diseases (AD/PD), Mar 2017, Vienna, Austria
Communication dans un congrès hal-01466122v1

Plate-forme d’imagerie préclinique AnimAge du CERMEP

Radu Bolbos , Jean-Baptiste Langlois , Caroline Bouillot , Véronique Gualda , Luc Zimmer
1er Congrès National d'Imagerie du Vivant (CNIV), Feb 2016, Paris, France
Communication dans un congrès hal-01285493v1
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In vivo evaluation of a hybrid nanoparticle for molecular imaging of amyloid aggregation

E. Ong , F. Vadcard , M. Verdurand , H. Rositi , F. Peyrin
10th annual meeting of the European Society for Molecular Imaging (ESMI) - European Molecular Imaging Meeting (EMIM), Mar 2015, Tübingen, Germany
Communication dans un congrès hal-01207666v1

Longitudinal consequences of hippocampal amyloid-beta fibrils injections on 5-HT1A receptors: an in vitro autoradiography study

M. Verdurand , A. Naeye , C. Vilallonga , F. Chauveau , L. Zimmer
World Molecular Imaging Congress, Sep 2015, Honolulu, United States
Communication dans un congrès hal-01207703v1
Image document

A screening assay in the search of an alpha-synuclein PET radioligand

Mathieu Verdurand , Meriem Mendjel-Herda , Elise Levigoureux , Sophie Lancelot , Waël Zeinyeh
10th annual meeting of the European Society for Molecular Imaging (ESMI) - European Molecular Imaging Meeting (EMIM), Mar 2015, Tübingen, Germany
Communication dans un congrès hal-01207682v1
Image document

A screening assay in the search of an alpha-synuclein PET radioligand

Mathieu Verdurand , Meriem Mendjel-Herda , Elise Levigoureux , Sophie Lancelot , Waël Zeinyeh
World Molecular Imaging Congress (WMIC 2015), Sep 2015, Honolulu, United States
Communication dans un congrès hal-01207698v1

Initial evaluation of [18F]F13714, a novel 5-HT1A receptor agonist in non-human primates

A. Tavares , G. Becker , O. Barret , T. Morley , D. Alagille
Annual Congress of the European Association of Nuclear Medicine 2013, Oct 2013, Lyon, France
Communication dans un congrès hal-00948404v1

PIXSIC, a wireless radiosensitive intracerebral probe to monitor PET radiotracers in anaesthetized and awake rat

L. Balasse , J. Maerk , S. Fieux , Frederic Pain , P. Gisquet
Annual Congress of the European Association of Nuclear Medicine 2013, Oct 2013, Lyon, France
Communication dans un congrès hal-00948325v1

A post-mortem study to compare the 5-HT1A receptor binding of a PET agonist and a PET antagonist in Alzheimer's disease

G. Becker , N. Streichenberger , T. Billard , B. Vacher , A. Newman-Tancredi
Annual Congress of the European Association of Nuclear Medicine 2013, Oct 2013, Lyon, France
Communication dans un congrès hal-00948356v1

Preclinical evaluation of serotonin 5-HT6 receptor radioligands for PET imaging

G. Becker , J. Colomb , T. Billard , L. Zimmer
Annual Congress of the European Association of Nuclear Medicine 2013, Oct 2013, Lyon, France
Communication dans un congrès hal-00948359v1

Radiosynthesis and radiopharmacological evaluation of fluorinated PET radioligands for the 5-HT6 receptors

G. Becker , J. Colomb , T. Billard , L. Zimmer
Society of Nuclear Medicine Congress 2013, Jun 2013, Vancouver, Canada. pp.326
Communication dans un congrès hal-00948473v1

Potential of the wireless radiosensitive intracerebral probe PIXSIC to monitor PET radiotracers in anaesthetized and awake rat

Laure Balasse , Julia Maerk , Sylvain Fieux , Frédéric Pain , Aurélie Genoux
WMIC'2013, World Molecular Imaging Congress, Savannah, Georgia, USA, Sep 2013, Savannah, Georgia, United States
Communication dans un congrès in2p3-01069277v1

A multi-atlas based method for automated anatomical rat brain MRI segmentation and extraction of PET kinetics

S. Lancelot , A. Hammers , J.-B. Langlois , C. Bouillot , L. Zimmer
Nouvelles méthodologies en imagerie du vivant, Dec 2012, Lyon, France
Communication dans un congrès hal-00828672v1

A multi-atlas based method for automated anatomical rat brain MRI segmentation and extraction of PET kinetics

S. Lancelot , A. Hammers , A. Slimen , C. Sahakian A. , E. Levigoureux
9th International Symposium on Functional Neuroreceptor Mapping of the Living Brain (NRM), Aug 2012, Baltimore, United States. pp.S171-S172
Communication dans un congrès hal-00830156v1

The ANIMAGE project: a multimodal imaging platform for small animal research

D. Sappey-Marinier , Olivier Beuf , C. Billotey , E. Chereul , J. Dupuy
2. International Conference on Imaging Technologies in Biomedical Sciences, May 2003, Athènes, Greece
Communication dans un congrès hal-02763821v1

PUFA and cerebral function: focus on monoaminergic neurotransmitters

Sylvie Chalon , Sylvie Vancassel , Luc Zimmer , Denis Guilloteau , Georges Durand
PUFA in Maternal and Child Health, 2000, Kansas City, United States
Communication dans un congrès hal-02840465v1
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5-HT1A biased agonists induce different hemodynamic responses, a pharmacological MRI study

Benjamin Vidal , Radu Bolbos , Jérôme Redouté , Jean-Baptiste Langlois , Sylvain Fieux
ECNP, 2017, Paris, France
Poster de conférence hal-04273484v1

PIXSIC-Characterisation of a Beta+ Intracerebral Wireless Probe for Functtional Imaging Coupled with Behavioural Studies Performed on Freely Moving Rats

Julia Maerk , Laure Balasse , Didier Benoit , Mathieu Benoit , Jean-Claude Clémens
WMIC'2012 World Molecular Imaging Congress, Sep 2012, Dublin, Ireland
Poster de conférence in2p3-00869594v1

Physical characterization of a wireless radiotracer detection system based on pixalated Silicon for in vivo brain studies in freely moving rats

Julia Maerk , Didier Benoit , Laure Balasse , Mathieu Benoit , Jean-Claude Clémens
IX ième Journée Scientifique BCP, Dec 2012, Marseille, France
Poster de conférence in2p3-00767714v1

Physical Characterization of a Wireless Radiotracer Detection System Based on Pixelated Silicon for in Vivo Brain Studies in Freely Moving Rats

Julia Maerk , Didier Benoit , Laure Balasse , Mathieu Benoit , Jean-Claude Clémens
2012 Nuclear Science Symposium, Medical Imaging Conference & Workshop on Room-Temperature Semiconductor X-Ray and Gamma-Ray Detectors, Oct 2012, Anaheim, Californie, United States
Poster de conférence in2p3-00757534v1

New Concept of a Submillimetric Pixellated Silicon Detector for in Vivo Brain Studies in Freely Moving Rodents

J. Maerk , D. Benoit , M. Benoit , J.-C. Clémens , D. Fougeron
2011 World Molecular Imaging Congress, Sep 2011, San Diego, United States
Poster de conférence in2p3-00628952v1

The effects of a total sleep deprivation on the brain 5-HT1A receptor binding: A pet study with [F-18]MPPF

Yazid Lakhdarchaouche , Thierry Faivre , Nicolas Costes , Luc Zimmer , Alain Nicolas
24th CINP Congress, Jun 2004, Paris, France. NTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, 7, pp.S286, 2004
Poster de conférence hal-02351542v1

Neurotransmission dopaminergique et nutrition : la déficience alimentaire en acides gras polyinsaturés n-3 modifie le système dopaminergique cortico-limbique chez le rat

Luc Zimmer , Sylvie Vancassel , Denis Guilloteau , Georges Durand , Sylvie Chalon
3. Colloque de la Société des Neurosciences, 1999, Marseille, France. 1999
Poster de conférence hal-02840396v1