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Rodrigo GUABIRABA
46%
Open access
114
Documents
Current affiliations
- 1002365
Researcher identifiers
rodrigo-guabiraba-
0000-0003-4005-1753
- IdRef : 229935125
Presentation
I am an immunopharmacologist (PhD) and senior research scientist at the INRAE (Tours). My research focuses on identifying and characterizing mediators of inflammation and the role of the intestinal microbiota in the chicken innate immune response to influenza virus along the “gut-lung axis”. Host’s effector mechanisms necessary to deal with infection are not necessarily the same that will exacerbate inflammation and drive disease. I thus aim to provide solid rationale on how mediators of inflammation and metabolites produced by the gut microbiota regulates immune functions at mucosal sites, therefore contributing to optimal viral clearance or to unwanted inflammation.
Research domains
Immunology
Immunotherapy
Veterinary medicine and animal Health
Skills
Cell biology and explant models
Host-pathogen interaction models
Avian immunology
Experimental pharmacology
Publications
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Physiopathology of Eimeria tenella infection and integrity of the intestinal barrier: influence of the microbiota13. International Coccidiosis Conference, Jun 2023, České Budějovice, Czech Republic
Conference papers
hal-04143368v1
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Uncovering the core principles of the gut-lung axis to enhance mucosal immunity in the chicken16. Meeting of the Avian Immunology Research Group (AIRG), Sep 2022, Newark, DE, United States
Conference papers
hal-03824181v1
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Impacts à court et à moyen terme d'une supplémentation précoce en xylanase-xos sur le métabolome et le microbiome caécal des poulets de chair14 ème Journées de la Recherche Avicole et Palmipèdes à Foie Gras (JRA), Mar 2022, Tours, France
Conference papers
hal-03775492v1
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Uncovering the core principles of the gut-lung axis to enhance mucosal immunity in the chickenJournées d'Animation Scientifique de la FéRI 2022 - FéRi Scientific Days 2022, Fédération de Recherche en Infectiologie (FéRI), Centre Val de Loire, Jul 2022, Joué-Lès-Tours, France
Conference papers
hal-03735525v1
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Effets de l’altération du microbiote intestinal, de la génétique et du mode d’élevage sur des paramètres d’immunocompétence de poules pondeusesSéminaire Métaprogramme - SANBA, Nov 2022, Paris, France
Conference papers
hal-04445373v1
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Development of a method for assessing the bioactivity of plant extracts on the antioxidative status and innate immunity in chickenWorld's Poultry Congress 2022, Aug 2022, Paris, France
Conference papers
hal-03953063v1
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Impact du microbiote intestinal et de ses métabolites sur le développement et la maturation du système immunitaire inné14. Journées de la Recherche Avicole et Palmipèdes à Foie-Gras (JRA), Mar 2022, Tours, France
Conference papers
hal-03771882v1
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Differentiated short and medium term impacts of early xylanase-xos supplementation on caecal metabolome and microbiome moy in broilerWorld Poultry Congress, Aug 2022, Paris, France
Conference papers
hal-04144164v1
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Physiopathology of Eimeria tenella infection and integrity of the intestinal barrier: influence of the microbiotaApiCOWplexa 2019. 5. International Meeting on Apicomplexan Parasites in Farm Animals, Oct 2019, Berlin, Germany
Conference papers
hal-03307268v1
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Evaluation de l'innocuité et des effets immunostimulants d'extraits végétaux sur lignées cellulaires de poulet13e Journées de la Recherche Avicole et Palmipèdes à Foie Gras, Mar 2019, Tours, France. 929 p
Conference papers
hal-04001296v1
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Evolution of innate immunity components during incubation of the avian eggCombined worshop of Fundamental physiology and Perinatal development in Poultry and Incubation and Fertility Research Group, Aug 2019, Tours, France. ⟨10.1399/eps.2019.291⟩
Conference papers
hal-02737061v1
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Influence du microbiote sur la physiopathologie de l'infection par Eimeria tenellaJournées d'Animation Scientifique du Département Santé Animale, Oct 2018, Nantes, France
Conference papers
hal-02733553v1
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A novel chicken cell culture model to explore the role of the vascular endothelium in the pathogenesis of avian influenza and Marek’s disease in gallinaceous poultry11. Symposium of the French Domestic Animal Immunology Network (IAD 2018), Mar 2018, Tours, France. 56 p
Conference papers
hal-02736481v1
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Intégrité de la barrière intestinale lors de l’infection par Eimeria tenella : importance des macrophages et l’influence du microbioteJournées d'animation scientifique de la fédération de recherche en infectiologie (FéRI), Jul 2018, Tours, France. 47 p
Conference papers
hal-02737465v1
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Activity of avian beta-defensins: beyond antibacterial11. Symposium of the French Domestic Animal Immunology Network (IAD 2018), Mar 2018, Tours, France. 56 p
Conference papers
hal-02737168v1
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Type I IFN stimulation primes chicken macrophages to an exacerbated inflammatory phenotype mediated by IFNβ following bacterial challenge11. Symposium of the French Domestic Animal Immunology Network (IAD 2018), Mar 2018, Tours, France. 56 p
Conference papers
hal-02734615v1
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Assessment of avian beta-defensins interaction with chicken cells14. Avian Immunology Research Group (AIRG) Meeting 2016, German Society for Immunology DGFI., Sep 2016, Herrsching am Ammersee, Germany
Conference papers
hal-02738823v1
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Assessment of avian beta-defensin 7 interactions with immune cells in vivo and in vitro5. Journées d'animation scientifique de la FéRI, Fédération de recherche en infectiologie (FéRI)., Jul 2016, Tours, France
Conference papers
hal-02795846v1
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Therapeutic potential of avian beta-defensins in experimental murine salmonellosisAMP2016 Antimicrobial Peptides Symposium, Centre National de la Recherche Scientifique (CNRS). FRA., Jun 2016, Montpellier, France
Conference papers
hal-02742837v1
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Type I IFN priming modulates pro-inflammatory response to E. coli LPS in chicken macrophages5. Journées d'animation scientifique de la FéRI, Fédération de recherche en infectiologie (FéRI)., Jul 2016, Tours, France
Conference papers
hal-02793469v1
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IL-33 and chemotherapy induced injurySeminars INEM CNRS Orléans, Centre National de la Recherche Scientifique (CNRS). FRA., Apr 2014, Orléans, France
Conference papers
hal-02792779v1
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Controlling inflammatory responses: Lessons from host-pathogen interaction and sterile injurySeminars UFMG, 2013
Conference papers
hal-02802064v1
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Dengue virus infection in miceSeminars UFSC, Universidade Federal de Santa Catarina (UFSC). BRA., 2012
Conference papers
hal-02804306v1
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IL-22 deficiency increases IL-17 production and contributes to inflammation and tissue damage in a mouse model of severe dengue virus infectionWIRM World Immune Regulation Meeting VI, Mar 2012, Davos, Switzerland
Conference papers
hal-02805468v1
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Il-22 is involved in the control of systemic and local inflammatory responses associated to dengue virus infection in mice35. Congresso da Sociedade Brasileira de Imunologia, Sociedade Brasileira de Imunologia., Nov 2010, Porto Alegro, Brazil
Conference papers
hal-02815675v1
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CC chemokine receptors play different roles in the pathogenesis of dengue virus infection in mice42. Congresso Brasileiro de Farmacologia e Terapêutica Experimental, Sociedade Brasileira de Farmacologia e Terapêutica Experimental., Oct 2010, Ribeirão Preto, Brazil
Conference papers
hal-02751197v1
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Biology of Addictive DrugsBiology Week UFMG, 2009
Conference papers
hal-02812300v1
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A Potential Major Role for the CCR5 Receptor in Mediating the Infection by Dengue Virus Serotype-2 and its Physiophatological Manifestations in Mice40. Congresso Brasileiro de Farmacologia e Terapêutica Experimental, Sociedade Brasileira de Farmacologia e Terapêutica Experimental., 2008, Águas de Lindóia, Brazil
Conference papers
hal-02814516v1
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Role of cannabinoid receptors in an experimental model of inflammatory angiogenesis13. International Congress of Immunology - ImmunoRio, Aug 2007, Rio de Janeiro, Brazil
Conference papers
hal-02812323v1
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Effects of a CXCR2 antagonist on bleomycin-induced pulmonary injury and fibrosis38. Congresso Brasileiro de Farmacologia e Terapêutica Experimental, 2006
Conference papers
hal-02756604v1
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Role of Cannabinoid Receptors in an Experimental Model of Inflammatory Angiogenesis38. Congresso Brasileiro de Farmacologia e Terapêutica Experimental, 2006
Conference papers
hal-02752404v1
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Mechanisms by which the Flavonoid Dioclein Decreases Cytokines and Chemokines Levels in vitro38. Congresso Brasileiro de Farmacologia e Terapêutica Experimental, Oct 2006, Ribeirão Preto, Brazil
Conference papers
hal-02757357v1
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Biology of Addictive DrugsBiology Week UFMG, 2006
Conference papers
hal-02813700v1
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Biology of Addictive DrugsBiology Week UFMG, 2005
Conference papers
hal-02827100v1
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Inflammation: Technical and Experimental ApproachBiology Week UEMG/Divinopolis, 2004
Conference papers
hal-02825244v1
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Antinociceptive, anti-edematogenic and anti-inflammatory effects of Lychnophora pinaster (arnica mineira) hydroalcoholic extract in miceInternational Symposium Nitric Oxide, Cytokines and Inflammation, Jun 2004, Rio de Janeiro, Brazil
Conference papers
hal-02826992v1
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Cannabis sativa and endocannabinoidsSeminars UEMG/Divinopolis, 2004
Conference papers
hal-02825246v1
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Effects of the flavonoid dioclein on cytokines and nitric oxide production by murine macrophages29. Meeting of the Brazilian Society of Immunology, Oct 2004, Ouro Preto, Brazil
Conference papers
hal-02825771v1
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IL-1B driven endogenous IL-10 production protects against the systemic and local acute inflammatory response following intestinal ischemia and reperfusion injury34. Congresso Brasileiro de Farmacologia e Terapêutica Experimental, 2002
Conference papers
hal-02825533v1
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DengueMorgan & Claypool Publishers, 104 p., 2014, Colloquium Series on Integrated Systems Physiology, 9781615045747. ⟨10.4199/C00103ED1V01Y201402ISP049⟩
Books
hal-02791802v1
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Innate defenses of the avian egg.Bernd Kaspers Karel Schat Thomas Göbel Lonneke Vervelde. Avian Immunology. 3rd Edition, Academic Press, 2021, 9780128187081
Book sections
hal-03336191v1
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Tumor-associated neutrophils (tans)Trends in stem sell proliferation and cancer research, Springer Science+Business Media, 2013, 978-94-007-6211-4
Book sections
hal-02806016v1
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HABILITATION À DIRIGER DES RECHERCHESSciences du Vivant [q-bio]. Université de Tours, 2021
Habilitation à diriger des recherches
tel-04161553v1
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