Romain Grossier

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Publications

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The benefit of coupling droplet microfluidics and multiphoton optical microscopy to study the crystallization of polymorphic substances: a case study with ortho -aminobenzoic acid

Hugo Cercel , Clément Brandel , Romain Rac , Clément Pinètre , Charline Gerard et al.

CrystEngComm, 2025, ⟨10.1039/D4CE01289E⟩

Article dans une revue hal-05121037v1
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Rapid Polymorphic Screening using Sessile Microdroplets: Competitive Nucleation of Mannitol Polymorphs

Ruel Cedeno , Romain Grossier , Nadine Candoni , Stéphane Veesler

CrystEngComm, 2024, 26 (37), pp.5235-5240. ⟨10.1039/d4ce00648h⟩

Article dans une revue hal-04623947v2
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Modular microfluidic platform for solubility measurement, nucleation statistics and polymorph screening of active pharmaceutical ingredients: Irbesartan, Rimonabant, Aripiprazole and Sulfathiazole

Mathilde Lambert , Romain Grossier , Mehdi Lagaize , Thirou Bactivelane , Vasile Heresanu et al.

Journal of Crystal Growth, 2023, 616, pp.127252

Article dans une revue hal-03892185v1
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CNT effective interfacial energy and pre-exponential kinetic factor from measured NaCl crystal nucleation time distributions in contracting microdroplets

Ruel Cedeno , Romain Grossier , Nadine Candoni , Nicolas Levernier , Adrian Flood et al.

The Journal of Chemical Physics, 2023, 158, pp.194705. ⟨10.1063/5.0143704⟩

Article dans une revue hal-03911818v3
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Microdroplet Approach for Measuring Aqueous Solubility and Nucleation Kinetics of a Metastable Polymorph: The case of KDP Phase IV

Ruel Cedeno , Romain Grossier , Nadine Candoni , Stéphane Veesler

Crystal Growth & Design, 2023, 23, pp.9052-9057. ⟨10.1021/acs.cgd.3c01086⟩

Article dans une revue hal-04206235v2
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Nucleation in Sessile Saline Microdroplets: Induction Time Measurement via Deliquescence-Recrystallization Cycling

Ruel Cedeno , Romain A Grossier , Mehdi Lagaize , D. Nerini , Nadine Candoni et al.

Faraday Discussions, 2022, 235, pp.183-197. ⟨10.1039/D1FD00090J⟩

Article dans une revue hal-03439155v3
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Evaporation Dynamics of Sessile Saline Microdroplets in Oil

Ruel Cedeno , Romain Grossier , Victoria Tishkova , Nadine Candoni , Adrian E. Flood et al.

Langmuir, 2022, 38, pp.9686-9696. ⟨10.1021/acs.langmuir.2c01269⟩

Article dans une revue hal-03440976v4
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Preparation of alginate hydrogel microparticles by gelation introducing cross-linkers using droplet-based microfluidics: a review of methods

Cheng Zhang , Romain A Grossier , Nadine Candoni , Stéphane Veesler

Biomaterials Research, 2021, 25 (1), pp.41. ⟨10.1186/s40824-021-00243-5⟩

Article dans une revue hal-02938090v6
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A microfluidic method generating monodispersed microparticles with controllable sizes and mechanical properties

Cheng Zhang , Romain A Grossier , Leda Lacaria , Felix Rico , Nadine A Candoni et al.

Chemical Engineering Science, 2020, 211, pp.115322. ⟨10.1016/j.ces.2019.115322⟩

Article dans une revue hal-02179400v3
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Microfluidics platform for polymorph screening directly from powder

Guillem Peybernès , Romain Grossier , Frédéric Villard , Philippe Letellier , Nadine Candoni et al.

Crystal Growth & Design, 2020, 20, pp.3882-3887

Article dans une revue hal-02477923v2
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Advances in the Use of Microfluidics to Study Crystallization Fundamentals

Nadine A Candoni , Romain Grossier , Mehdi Lagaize , Stéphane Veesler

Annual Review of Chemical and Biomolecular Engineering, 2019, 10 (1), pp.59-83. ⟨10.1146/annurev-chembioeng-060718-030312⟩

Article dans une revue hal-01959318v1
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Microfluidics set-up rapidly measures solubility directly from powder

Guillem Peybernès , Romain A Grossier , Frédéric Villard , Philippe Letellier , Mehdi Lagaize et al.

Organic Process Research and Development, 2018, 22, pp.1856-1860. ⟨10.1021/acs.oprd.8b00300⟩

Article dans une revue hal-01899746v2
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A parameter to probe microdroplet dynamics and crystal nucleation

R. Grossier , Victoria Tishkova , R. Morin , S. Veesler

AIP Advances, 2018, 8 (7), pp.075324. ⟨10.1063/1.5034443⟩

Article dans une revue hal-01744090v2
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A chemical library to screen protein and protein-ligand crystallization using a versatile microfluidic platform

Charline J. J. Gerard , Gilles Ferry , Laurent M Vuillard , Jean A. Boutin , Nathalie A Ferte et al.

Crystal Growth & Design, 2018, 18, pp.5130-5137. ⟨10.1021/acs.cgd.8b00572⟩

Article dans une revue hal-01768463v1
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Crystallization via tubing microfluidics permits both in situ and ex situ X-ray diffraction

Charline J. J. Gerard , Gilles Ferry , Laurent M Vuillard , Jean A Boutin , Léonard M.G. Chavas et al.

Acta crystallographica Section F : Structural biology communications [2014-..], 2017, 73 (10), pp.574 - 578. ⟨10.1107/S2053230X17013826⟩

Article dans une revue hal-01493598v2
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Microfluidic platform for optimization of crystallization conditions

Shuheng A Zhang , Charline J. J. Gerard , Aziza A Ikni , Gilles Ferry , Laurent M Vuillard et al.

Journal of Crystal Growth, 2017, 472, pp.18-28. ⟨10.1016/j.jcrysgro.2017.01.026⟩

Article dans une revue hal-01392627v2

Localizing and inducing primary nucleation

Z. Hammadi , R. Grossier , Aziza Ikni , N. Candoni , R. Morin et al.

Faraday Discussions, 2015, 179, pp.489-501. ⟨10.1039/c4fd00274a⟩

Article dans une revue hal-01171394v1
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Small-volume nucleation

Zoubida Hammadi , Nadine Candoni , Romain Grossier , Manuel Ildefonso , Roger Morin et al.

Comptes Rendus. Physique, 2013, 14 (2-3), pp.192-198. ⟨10.1016/j.crhy.2012.12.004⟩

Article dans une revue hal-04463247v1
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Monitoring Picoliter Sessile Microdroplet Dynamics Shows That Size Does Not Matter

I. Rodriguez-Ruiz , Z. Hammadi , R. Grossier , J. Gomez-Morales , S. Veesler

Langmuir, 2013, 29 (41), pp.12628-12632. ⟨10.1021/la402735k⟩

Article dans une revue hal-00914755v1

Small-volumes nucleation

Z. Hammadi , N. Candoni , R. Grossier , Manuel Ildefonso , R. Morin et al.

Comptes Rendus. Physique, 2013, 14, pp.192-198

Article dans une revue hal-00810510v1

Nanotechnologies dedicated to nucleation control

N. Candoni , R. Grossier , Manuel Ildefonso , E. Revalor , N. Ferté et al.

International Journal of Nanotechnology, 2012, 9 (3-7), pp.439-459

Article dans une revue hal-00696846v1

Practical Physics Behind Growing Crystals of Biological Macromolecules

N. Candoni , R. Grossier , Z. Hammadi , R. Morin , S. Veesler

Protein and Peptide Letters, 2012, 19, pp.714-724

Article dans une revue hal-00724324v1
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Generating nanoliter to femtoliter microdroplets with ease

R. Grossier , Z. Hammadi , R. Morin , A. Magnaldo , S. Veesler

Applied Physics Letters, 2011, 98 (9), pp.091916-3

Article dans une revue hal-00581232v1

Predictive nucleation of Crystals in Small Volumes and Its Consequences

R. Grossier , Z. Hammadi , R. Morin , S. Veesler

Physical Review Letters, 2011, 107 (2), pp.025504

Article dans une revue hal-00624848v1

Usual and Unusual Crystallization from Solution

E. Revalor , Z. Hammadi , J.P. Astier , R. Grossier , E. Garcia et al.

Journal of Crystal Growth, 2010, 312, pp.939-946

Article dans une revue hal-00475837v1

Ultra-fast crystallization due to Confinement

R. Grossier , A. Magnaldo , S. Veesler

Journal of Crystal Growth, 2010, 312, pp.487-489

Article dans une revue hal-00453710v1

Reaching one single and stable critical cluster through finite sized systems

R. Grossier , S. Veesler

Crystal Growth & Design, 2009, 9 (4), pp.1917-1922

Article dans une revue hal-00386957v1
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The effect of ultrasound on crystallization-precipitation processes : some examples and a new segregation model

John A. Dodds , Fabienne Espitalier , Olivier Louisnard , Romain Grossier , René David et al.

Particle & Particle Systems Characterization, 2007, 24 (1), p.18-28. ⟨10.1002/ppsc.200601046⟩

Article dans une revue hal-01844743v1
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Segregation of a liquid mixture by a radially oscillating bubble

Olivier Louisnard , Francisco J. Gomez , Romain Grossier

Journal of Fluid Mechanics, 2007, 577, pp.385-415. ⟨10.1017/S002211200700479X⟩

Article dans une revue hal-01717681v1
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Mixture segregation by an inertial cavitation bubble

R. Grossier , Olivier Louisnard , Y. Vargas

Ultrasonics Sonochemistry, 2007, 14 (4), pp.431-437. ⟨10.1016/j.ultsonch.2006.10.010⟩

Article dans une revue hal-01717683v1

Mise en évidence expérimentale de la ségrégation d'espèces par une bulle de cavitation

Romain Grossier , Olivier Louisnard , Yolanda Vargas Hernandez , Fabienne Espitalier

CFTL 2006 -Congrès Francophone de Techniques Laser, Sep 2006, Toulouse, France. p.423-430

Communication dans un congrès hal-01780079v1
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Addressing the stochasticity of nucleation: Practical approaches

N. Candoni , Z. Hammadi , R. Grossier , Manuel Ildefonso , R. Morin et al.

Rui Tamura, Mikiji Miyata. Advances in Organic Crystal Chemistry, Springer, pp.95-113, 2015, 978-4-431-55554-4. ⟨10.1007/978-4-431-55555-1_6⟩

Chapitre d'ouvrage hal-01803259v1