Romain Guinamard

38
Documents

Publications

Publications

Protection of the human aortic valve interstitial cells against radiation-induced remodeling by repression of the TRPM4 channel

Margaux Aize , Laura Brard , Corentin Kerevel , Arthur Boilève , Harlyne Mpweme Bangando et al.

American Journal of Physiology - Cell Physiology, 2025, 329 (5), pp.C1487-C1497. ⟨10.1152/ajpcell.00535.2025⟩

Article dans une revue hal-05409779v1

Contribution of the TRPM4 Channel to Osteogenic Differentiation of Human Aortic Valve Interstitial Cells

Margaux Aize , Arthur Boilève , Benoit Roussel , Laura Brard , Harlyne Mpweme Bangando et al.

Journal of the American Heart Association, 2025, 14 (8), ⟨10.1161/JAHA.124.038542⟩

Article dans une revue hal-05149143v1

Pathophysiological Roles of the TRPV4 Channel in the Heart

Sébastien Chaigne , Solène Barbeau , Thomas Ducret , Romain Guinamard , David Benoist

Cells, 2023, 12 (12), pp.1654. ⟨10.3390/cells12121654⟩

Article dans une revue hal-05153688v1

TRPM4 contribution in mouse uterine contractions

Alexandre Fouchet , Harlyne Mpweme Bangando , Margaux Aize , Christophe Simard , Romain Guinamard

Reproduction [Cambridge], 2023, 166 (2), pp.77-87. ⟨10.1530/REP-22-0484⟩

Article dans une revue hal-05148983v1

TRPM4 Participates in Irradiation-Induced Aortic Valve Remodeling in Mice

Harlyne Mpweme Bangando , Christophe Simard , Margaux Aize , Alexandre Lebrun , Alain Manrique et al.

Cancers, 2022, 14 (18), pp.4477. ⟨10.3390/cancers14184477⟩

Article dans une revue hal-05153761v1

TRPA1 and TRPV1, do we hold you in our heart?

Romain Guinamard , Thomas Hof

Acta Physiologica, 2021, 232 (4), pp.5860. ⟨10.1111/apha.13695⟩

Article dans une revue hal-05149127v1

TRPM4 Participates in Aldosterone-Salt-Induced Electrical Atrial Remodeling in Mice

Christophe Simard , Virginie Ferchaud , Laurent Sallé , Paul Milliez , Alain Manrique et al.

Cells, 2021, 10 (3), pp.636. ⟨10.3390/cells10030636⟩

Article dans une revue hal-05154319v1
Deposit thumbnail

Transient Receptor Potential Vanilloid 4 channel participates in mouse ventricular electrical activity

Sebastien Chaigne , Guillaume Cardouat , Julien Louradour , Fanny Vaillant , Sabine Charron et al.

AJP - Heart and Circulatory Physiology, 2021, 320 (3), ⟨10.1152/ajpheart.00497.2020⟩

Article dans une revue hal-03113297v1

TRPM4 non-selective cation channel in human atrial fibroblast growth

Christophe Simard , Christophe Magaud , Racim Adjlane , Quentin Dupas , Laurent Sallé et al.

Pflügers Archiv European Journal of Physiology, 2020, 472 (12), pp.1719-1732. ⟨10.1007/s00424-020-02476-0⟩

Article dans une revue hal-05485051v1

TRPM4 non-selective cation channel in human atrial fibroblast growth

Christophe Simard , Christophe Magaud , Racim Adjlane , Quentin Dupas , Laurent Sallé et al.

Pflügers Archiv European Journal of Physiology, 2020, 472 (12), pp.1719-1732. ⟨10.1007/s00424-020-02476-0⟩

Article dans une revue hal-03715736v1

Transient receptor potential channels in cardiac health and disease

Thomas Hof , Sébastien Chaigne , Alice Récalde , Laurent Sallé , Fabien Brette et al.

Nature Reviews Cardiology, 2019, 16 (6), pp.344-360. ⟨10.1038/s41569-018-0145-2⟩

Article dans une revue hal-05154816v1
Deposit thumbnail

Trpm4 ion channels in pre-Bötzinger complex interneurons are essential for breathing motor pattern but not rhythm

Maria Cristina D. Picardo , Yae Sugimura , Kaitlyn Dorst , Prajkta Kallurkar , Victoria Akins et al.

PLoS Biology, 2019, 17 (2), pp.e2006094. ⟨10.1371/journal.pbio.2006094⟩

Article dans une revue hal-05155692v1

Argon Exposure Induces Postconditioning in Myocardial Ischemia–Reperfusion

Sandrine Lemoine , Katrien Blanchart , Mathieu Souplis , Adrien Lemaitre , Damien Legallois et al.

Journal of Cardiovascular Pharmacology and Therapeutics, 2017, 22 (6), pp.564-573. ⟨10.1177/1074248417702891⟩

Article dans une revue hal-05156476v1
Deposit thumbnail

TRPM4 non-selective cation channel variants in long QT syndrome

Thomas Hof , Hui Liu , Laurent Sallé , Jean-Jacques Schott , Corinne Ducreux et al.

BMC Medical Genetics, 2017, Equipe I, 18 (1), pp.31. ⟨10.1186/s12881-017-0397-4⟩

Article dans une revue hal-01832144v1

A Pipeline for the Generation of Realistic 3D Synthetic Echocardiographic Sequences: Methodology and Open-Access Database

Romain Guinamard , Patrice Bouvagnet , Thomas Hof , Hui Liu , Christophe Simard et al.

Cardiovascular Research, 2015, 108 (1), pp.21-30. ⟨10.1093/cvr/cvv213⟩

Article dans une revue hal-05156805v1

TRPM4 non‐selective cation channels influence action potentials in rabbit Purkinje fibres

Thomas Hof , Laurent Sallé , Laurent Coulbault , Romain Richer , Joachim Alexandre et al.

The Journal of Physiology, 2015, 594 (2), pp.295-306. ⟨10.1113/JP271347⟩

Article dans une revue hal-05156558v1
Deposit thumbnail

Rapid and MR-Independent IK1 Activation by Aldosterone during Ischemia-Reperfusion

Joachim Alexandre , Thomas Hof , Paolo Emilio Puddu , René Rouet , Romain Guinamard et al.

PLoS ONE, 2015, 10 (7), pp.e0132592. ⟨10.1371/journal.pone.0132592⟩

Article dans une revue hal-05156829v1

Proarrhythmic Effects of Aldosterone During Myocardial Ischemia–Reperfusion

Joachim Alexandre , Paolo-Emilio Puddu , Christophe Simard , Thomas Hof , Laurent Sallé et al.

Journal of Cardiovascular Pharmacology, 2014, 64 (2), pp.134-141. ⟨10.1097/FJC.0000000000000097⟩

Article dans une revue hal-05165497v1

Epac activator critically regulates action potential duration by decreasing potassium current in rat adult ventricle

Fabien Brette , Erick Blandin , Christophe Simard , Romain Guinamard , Laurent Sallé

Journal of Molecular and Cellular Cardiology, 2013, 57, pp.96-105. ⟨10.1016/j.yjmcc.2013.01.012⟩

Article dans une revue hal-05165513v1

The TRPM4 non-selective cation channel contributes to the mammalian atrial action potential

Christophe Simard , Thomas Hof , Zakia Keddache , Pierre Launay , Romain Guinamard

Journal of Molecular and Cellular Cardiology, 2013, 59, pp.11-19. ⟨10.1016/j.yjmcc.2013.01.019⟩

Article dans une revue hal-05165507v1

Molecular Genetics and Functional Anomalies in a Series of 248 Brugada Cases with 11 Mutations in the TRPM4 Channel

Hui Liu , Stéphanie Chatel , Christophe Simard , Ninda Syam , Laurent Salle et al.

PLoS ONE, 2013, 8 (1), pp.e54131. ⟨10.1371/journal.pone.0054131⟩

Article dans une revue hal-05165511v1

Flufenamic acid as an ion channel modulator

Romain Guinamard , Christophe Simard , Christopher del Negro

Pharmacology & Therapeutics, 2013, 138 (2), pp.272-284. ⟨10.1016/j.pharmthera.2013.01.012⟩

Article dans une revue hal-05165518v1

Implication of the TRPM4 nonselective cation channel in mammalian sinus rhythm

Thomas Hof , Christophe Simard , René Rouet , Laurent Sallé , Romain Guinamard

Heart Rhythm, 2013, 10 (11), pp.1683-1689. ⟨10.1016/j.hrthm.2013.08.014⟩

Article dans une revue hal-05165500v1

Transient receptor potential melastatin 4 inhibitor 9‐phenanthrol abolishes arrhythmias induced by hypoxia and re‐oxygenation in mouse ventricle

Christophe Simard , Laurent Sallé , René Rouet , Romain Guinamard

British Journal of Pharmacology, 2012, 165 (7), pp.2354-2364. ⟨10.1111/j.1476-5381.2011.01715.x⟩

Article dans une revue hal-05165523v1

A calcium-permeable non-selective cation channel in the thick ascending limb apical membrane of the mouse kidney

Romain Guinamard , Marc Paulais , Stéphane Lourdel , Jacques Teulon

Biochimica et Biophysica Acta:Biomembranes, 2012, 1818 (5), pp.1135-1141. ⟨10.1016/j.bbamem.2011.12.024⟩

Article dans une revue inserm-02448132v1

The Non-selective Monovalent Cationic Channels TRPM4 and TRPM5

Romain Guinamard , Laurent Sallé , Christophe Simard

Advances in Experimental Medicine and Biology, 2011, Advances in Experimental Medicine and Biology, 704, pp.147-171. ⟨10.1007/978-94-007-0265-3_8⟩

Article dans une revue hal-05165531v1

9-Phenanthrol inhibits human TRPM4 but not TRPM5 cationic channels

Teddy Grand , Marie Demion , Caroline Norez , Yvette Mettey , Pierre Launay et al.

British Journal of Pharmacology, 2008, 153 (8), pp.1697-1705. ⟨10.1038/bjp.2008.38⟩

Article dans une revue hal-00393981v1

The heart rate-lowering agent ivabradine inhibits the pacemaker current I(f) in human atrial myocytes

Antoun El Chemaly , Christophe Magaud , Sylvie Patri , Christophe Jayle , Romain Guinamard et al.

Journal of Cardiovascular Electrophysiology, 2007, 18 (11), pp.1190-1196. ⟨10.1111/j.1540-8167.2007.00955.x⟩

Article dans une revue istex hal-00393733v1

MOLECULAR REGULATION AND PHARMACOLOGY OF PACEMAKER CHANNELS

Patrick Bois , Romain Guinamard , Antoun El Chemaly , Jean François Faivre , Jocelyn Bescond

Current Pharmaceutical Design, 2007, 13 (23), pp.2338-2349

Article dans une revue hal-00394274v1
Deposit thumbnail

Involvement of Transient Receptor Potential proteins in cardiac hypertrophy

Romain Guinamard , Patrick Bois

Biochimica et Biophysica Acta - Molecular Basis of Disease, 2007, 1772 (8), pp.885-894. ⟨10.1016/j.bbadis.2007.02.007⟩

Article dans une revue hal-00562770v1

A voltage-activated proton current in human cardiac fibroblasts

Antoun El Chemaly , Romain Guinamard , Marie Demion , Nassim Fares , Victor Jebara et al.

Biochemical and Biophysical Research Communications, 2006, 340 (2), pp.512-516. ⟨10.1016/j.bbrc.2005.12.038⟩

Article dans une revue istex hal-05319956v1

Calcium-Activated Nonselective Cation Channels in Mammalian Cardiomyocytes

Romain Guinamard , Marie Demion , Aurelien Chatelier , Patrick Bois

Trends in Cardiovascular Medicine, 2006, 16 (7), pp.245-250. ⟨10.1016/j.tcm.2006.04.007⟩

Article dans une revue hal-05024506v1

Functional Expression of the TRPM4 Cationic Current in Ventricular Cardiomyocytes From Spontaneously Hypertensive Rats

Romain Guinamard , Marie Demion , Christophe Magaud , Daniel Potreau , Patrick Bois

Hypertension, 2006, 48 (4), pp.587-594. ⟨10.1161/01.HYP.0000237864.65019.a5⟩

Article dans une revue hal-04279693v1

Exploration of the Basolateral Chloride Channels in the Renal Tubule using

Jacques Teulon , Stéphane Lourdel , Antoine Nissant , Marc Paulais , Romain Guinamard et al.

Nephron Physiology, 2005, 99 (2), p64-p68. ⟨10.1159/000082972⟩

Article dans une revue inserm-02448169v1

Functional characterization of a Ca 2+ ‐activated non‐selective cation channel in human atrial cardiomyocytes

Romain Guinamard , Aurélien Chatelier , Marie Demion , Daniel Potreau , Sylvie Patri et al.

The Journal of Physiology, 2004, 558 (1), pp.75-83. ⟨10.1113/jphysiol.2004.063974⟩

Article dans une revue hal-05024483v1

Activation of the Ca<sup>2+</sup>‐Activated Nonselective Cation Channel by Diacylglycerol Analogues in Rat Cardiomyocytes

Romain Guinamard , Aurélien Chatelier , Jacques Lenfant , Patrick Bois

Journal of Cardiovascular Electrophysiology, 2004, 15 (3), pp.342-348. ⟨10.1046/j.1540-8167.2004.03477.x⟩

Article dans une revue hal-05024478v1

Cl- absorption across the thick ascending limb is not altered in cystic fibrosis mice. A role for a pseudo-CFTR Cl- channel

Pedro Marvao , Marie‐celeste de Jesus Ferreira , Cedric Bailly , Marc Paulais , Marcelle Bens et al.

Journal of Clinical Investigation, 1998, 102 (11), pp.1986-1993. ⟨10.1172/JCI4074⟩

Article dans une revue inserm-02448190v1

Inhibition of a small-conductance cAMP-dependent Cl- channel in the mouse thick ascending limb at low internal pH.

R. Guinamard , M. Paulais , J. Teulon

The Journal of Physiology, 1996, 490 (3), pp.759-765. ⟨10.1113/jphysiol.1996.sp021183⟩

Article dans une revue inserm-02448212v1