Romain Guinamard

37
Documents

Publications

Publications

Protection of the human aortic valve interstitial cells against radiation-induced remodeling by repression of the TRPM4 channel

Margaux Aize , Laura Brard , Corentin Kerevel , Arthur Boilève , Harlyne Mpweme Bangando et al.
American Journal of Physiology - Cell Physiology, 2025, 329 (5), pp.C1487-C1497. ⟨10.1152/ajpcell.00535.2025⟩
Article dans une revue hal-05409779 v1

Contribution of the TRPM4 Channel to Osteogenic Differentiation of Human Aortic Valve Interstitial Cells

Margaux Aize , Arthur Boilève , Benoit Roussel , Laura Brard , Harlyne Mpweme Bangando et al.
Journal of the American Heart Association, 2025, 14 (8), ⟨10.1161/JAHA.124.038542⟩
Article dans une revue hal-05149143 v1

TRPM4 contribution in mouse uterine contractions

Alexandre Fouchet , Harlyne Mpweme Bangando , Margaux Aize , Christophe Simard , Romain Guinamard
Reproduction [Cambridge], 2023, 166 (2), pp.77-87. ⟨10.1530/REP-22-0484⟩
Article dans une revue hal-05148983 v1

Pathophysiological Roles of the TRPV4 Channel in the Heart

Sébastien Chaigne , Solène Barbeau , Thomas Ducret , Romain Guinamard , David Benoist
Cells, 2023, 12 (12), pp.1654. ⟨10.3390/cells12121654⟩
Article dans une revue hal-05153688 v1

TRPM4 Participates in Irradiation-Induced Aortic Valve Remodeling in Mice

Harlyne Mpweme Bangando , Christophe Simard , Margaux Aize , Alexandre Lebrun , Alain Manrique et al.
Cancers, 2022, 14 (18), pp.4477. ⟨10.3390/cancers14184477⟩
Article dans une revue hal-05153761 v1
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Transient Receptor Potential Vanilloid 4 channel participates in mouse ventricular electrical activity

Sebastien Chaigne , Guillaume Cardouat , Julien Louradour , Fanny Vaillant , Sabine Charron et al.
AJP - Heart and Circulatory Physiology, 2021, 320 (3), ⟨10.1152/ajpheart.00497.2020⟩
Article dans une revue hal-03113297 v1

TRPM4 Participates in Aldosterone-Salt-Induced Electrical Atrial Remodeling in Mice

Christophe Simard , Virginie Ferchaud , Laurent Sallé , Paul Milliez , Alain Manrique et al.
Cells, 2021, 10 (3), pp.636. ⟨10.3390/cells10030636⟩
Article dans une revue hal-05154319 v1

TRPA1 and TRPV1, do we hold you in our heart?

Romain Guinamard , Thomas Hof
Acta Physiologica, 2021, 232 (4), pp.5860. ⟨10.1111/apha.13695⟩
Article dans une revue hal-05149127 v1

TRPM4 non-selective cation channel in human atrial fibroblast growth

Christophe Simard , Christophe Magaud , Racim Adjlane , Quentin Dupas , Laurent Sallé et al.
Pflügers Archiv European Journal of Physiology, 2020, 472 (12), pp.1719-1732. ⟨10.1007/s00424-020-02476-0⟩
Article dans une revue hal-03715736 v1

Transient receptor potential channels in cardiac health and disease

Thomas Hof , Sébastien Chaigne , Alice Récalde , Laurent Sallé , Fabien Brette et al.
Nature Reviews Cardiology, 2019, 16 (6), pp.344-360. ⟨10.1038/s41569-018-0145-2⟩
Article dans une revue hal-05154816 v1

Trpm4 ion channels in pre-Bötzinger complex interneurons are essential for breathing motor pattern but not rhythm

Maria Cristina D. Picardo , Yae Sugimura , Kaitlyn Dorst , Prajkta Kallurkar , Victoria Akins et al.
PLoS Biology, 2019, 17 (2), pp.e2006094. ⟨10.1371/journal.pbio.2006094⟩
Article dans une revue hal-05155692 v1
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TRPM4 non-selective cation channel variants in long QT syndrome

Thomas Hof , Hui Liu , Laurent Sallé , Jean-Jacques Schott , Corinne Ducreux et al.
BMC Medical Genetics, 2017, Equipe I, 18 (1), pp.31. ⟨10.1186/s12881-017-0397-4⟩
Article dans une revue hal-01832144 v1

Argon Exposure Induces Postconditioning in Myocardial Ischemia–Reperfusion

Sandrine Lemoine , Katrien Blanchart , Mathieu Souplis , Adrien Lemaitre , Damien Legallois et al.
Journal of Cardiovascular Pharmacology and Therapeutics, 2017, 22 (6), pp.564-573. ⟨10.1177/1074248417702891⟩
Article dans une revue hal-05156476 v1

A Pipeline for the Generation of Realistic 3D Synthetic Echocardiographic Sequences: Methodology and Open-Access Database

Romain Guinamard , Patrice Bouvagnet , Thomas Hof , Hui Liu , Christophe Simard et al.
Cardiovascular Research, 2015, 108 (1), pp.21-30. ⟨10.1093/cvr/cvv213⟩
Article dans une revue hal-05156805 v1

TRPM4 non‐selective cation channels influence action potentials in rabbit Purkinje fibres

Thomas Hof , Laurent Sallé , Laurent Coulbault , Romain Richer , Joachim Alexandre et al.
The Journal of Physiology, 2015, 594 (2), pp.295-306. ⟨10.1113/JP271347⟩
Article dans une revue hal-05156558 v1

Rapid and MR-Independent IK1 Activation by Aldosterone during Ischemia-Reperfusion

Joachim Alexandre , Thomas Hof , Paolo Emilio Puddu , René Rouet , Romain Guinamard et al.
PLoS ONE, 2015, 10 (7), pp.e0132592. ⟨10.1371/journal.pone.0132592⟩
Article dans une revue hal-05156829 v1

Proarrhythmic Effects of Aldosterone During Myocardial Ischemia–Reperfusion

Joachim Alexandre , Paolo-Emilio Puddu , Christophe Simard , Thomas Hof , Laurent Sallé et al.
Journal of Cardiovascular Pharmacology, 2014, 64 (2), pp.134-141. ⟨10.1097/FJC.0000000000000097⟩
Article dans une revue hal-05165497 v1

Epac activator critically regulates action potential duration by decreasing potassium current in rat adult ventricle

Fabien Brette , Erick Blandin , Christophe Simard , Romain Guinamard , Laurent Sallé
Journal of Molecular and Cellular Cardiology, 2013, 57, pp.96-105. ⟨10.1016/j.yjmcc.2013.01.012⟩
Article dans une revue hal-05165513 v1

Molecular Genetics and Functional Anomalies in a Series of 248 Brugada Cases with 11 Mutations in the TRPM4 Channel

Hui Liu , Stéphanie Chatel , Christophe Simard , Ninda Syam , Laurent Salle et al.
PLoS ONE, 2013, 8 (1), pp.e54131. ⟨10.1371/journal.pone.0054131⟩
Article dans une revue hal-05165511 v1

The TRPM4 non-selective cation channel contributes to the mammalian atrial action potential

Christophe Simard , Thomas Hof , Zakia Keddache , Pierre Launay , Romain Guinamard
Journal of Molecular and Cellular Cardiology, 2013, 59, pp.11-19. ⟨10.1016/j.yjmcc.2013.01.019⟩
Article dans une revue hal-05165507 v1

Flufenamic acid as an ion channel modulator

Romain Guinamard , Christophe Simard , Christopher del Negro
Pharmacology and Therapeutics, 2013, 138 (2), pp.272-284. ⟨10.1016/j.pharmthera.2013.01.012⟩
Article dans une revue hal-05165518 v1

Implication of the TRPM4 nonselective cation channel in mammalian sinus rhythm

Thomas Hof , Christophe Simard , René Rouet , Laurent Sallé , Romain Guinamard
Heart Rhythm, 2013, 10 (11), pp.1683-1689. ⟨10.1016/j.hrthm.2013.08.014⟩
Article dans une revue hal-05165500 v1

Transient receptor potential melastatin 4 inhibitor 9‐phenanthrol abolishes arrhythmias induced by hypoxia and re‐oxygenation in mouse ventricle

Christophe Simard , Laurent Sallé , René Rouet , Romain Guinamard
British Journal of Pharmacology, 2012, 165 (7), pp.2354-2364. ⟨10.1111/j.1476-5381.2011.01715.x⟩
Article dans une revue hal-05165523 v1

A calcium-permeable non-selective cation channel in the thick ascending limb apical membrane of the mouse kidney

Romain Guinamard , Marc Paulais , Stéphane Lourdel , Jacques Teulon
Biochimica et Biophysica Acta:Biomembranes, 2012, 1818 (5), pp.1135-1141. ⟨10.1016/j.bbamem.2011.12.024⟩
Article dans une revue inserm-02448132 v1

The Non-selective Monovalent Cationic Channels TRPM4 and TRPM5

Romain Guinamard , Laurent Sallé , Christophe Simard
Advances in Experimental Medicine and Biology, 2011, Advances in Experimental Medicine and Biology, 704, pp.147-171. ⟨10.1007/978-94-007-0265-3_8⟩
Article dans une revue hal-05165531 v1

9-Phenanthrol inhibits human TRPM4 but not TRPM5 cationic channels

Teddy Grand , Marie Demion , Caroline Norez , Yvette Mettey , Pierre Launay et al.
British Journal of Pharmacology, 2008, 153 (8), pp.1697-1705. ⟨10.1038/bjp.2008.38⟩
Article dans une revue hal-00393981 v1
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Involvement of Transient Receptor Potential proteins in cardiac hypertrophy

Romain Guinamard , Patrick Bois
Biochimica et Biophysica Acta - Molecular Basis of Disease, 2007, 1772 (8), pp.885-894. ⟨10.1016/j.bbadis.2007.02.007⟩
Article dans une revue hal-00562770 v1

The heart rate-lowering agent ivabradine inhibits the pacemaker current I(f) in human atrial myocytes

Antoun El Chemaly , Christophe Magaud , Sylvie Patri , Christophe Jayle , Romain Guinamard et al.
Journal of Cardiovascular Electrophysiology, 2007, 18 (11), pp.1190-1196. ⟨10.1111/j.1540-8167.2007.00955.x⟩
Article dans une revue istex hal-00393733 v1

MOLECULAR REGULATION AND PHARMACOLOGY OF PACEMAKER CHANNELS

Patrick Bois , Romain Guinamard , Antoun El Chemaly , Jean François Faivre , Jocelyn Bescond
Current Pharmaceutical Design, 2007, 13 (23), pp.2338-2349
Article dans une revue hal-00394274 v1

Calcium-Activated Nonselective Cation Channels in Mammalian Cardiomyocytes

Romain Guinamard , Marie Demion , Aurelien Chatelier , Patrick Bois
Trends in Cardiovascular Medicine, 2006, 16 (7), pp.245-250. ⟨10.1016/j.tcm.2006.04.007⟩
Article dans une revue hal-05024506 v1

A voltage-activated proton current in human cardiac fibroblasts

Antoun El Chemaly , Romain Guinamard , Marie Demion , Nassim Fares , Victor Jebara et al.
Biochemical and Biophysical Research Communications, 2006, 340 (2), pp.512-516. ⟨10.1016/j.bbrc.2005.12.038⟩
Article dans une revue istex hal-05319956 v1

Functional Expression of the TRPM4 Cationic Current in Ventricular Cardiomyocytes From Spontaneously Hypertensive Rats

Romain Guinamard , Marie Demion , Christophe Magaud , Daniel Potreau , Patrick Bois
Hypertension, 2006, 48 (4), pp.587-594. ⟨10.1161/01.HYP.0000237864.65019.a5⟩
Article dans une revue hal-04279693 v1

Exploration of the Basolateral Chloride Channels in the Renal Tubule using

Jacques Teulon , Stéphane Lourdel , Antoine Nissant , Marc Paulais , Romain Guinamard et al.
Nephron Physiology, 2005, 99 (2), p64-p68. ⟨10.1159/000082972⟩
Article dans une revue inserm-02448169 v1

Functional characterization of a Ca 2+ ‐activated non‐selective cation channel in human atrial cardiomyocytes

Romain Guinamard , Aurélien Chatelier , Marie Demion , Daniel Potreau , Sylvie Patri et al.
The Journal of Physiology, 2004, 558 (1), pp.75-83. ⟨10.1113/jphysiol.2004.063974⟩
Article dans une revue hal-05024483 v1

Activation of the Ca<sup>2+</sup>‐Activated Nonselective Cation Channel by Diacylglycerol Analogues in Rat Cardiomyocytes

Romain Guinamard , Aurélien Chatelier , Jacques Lenfant , Patrick Bois
Journal of Cardiovascular Electrophysiology, 2004, 15 (3), pp.342-348. ⟨10.1046/j.1540-8167.2004.03477.x⟩
Article dans une revue hal-05024478 v1

Cl- absorption across the thick ascending limb is not altered in cystic fibrosis mice. A role for a pseudo-CFTR Cl- channel

Pedro Marvao , Marie‐celeste de Jesus Ferreira , Cedric Bailly , Marc Paulais , Marcelle Bens et al.
Journal of Clinical Investigation, 1998, 102 (11), pp.1986-1993. ⟨10.1172/JCI4074⟩
Article dans une revue inserm-02448190 v1

Inhibition of a small-conductance cAMP-dependent Cl- channel in the mouse thick ascending limb at low internal pH.

R. Guinamard , M. Paulais , J. Teulon
The Journal of Physiology, 1996, 490 (3), pp.759-765. ⟨10.1113/jphysiol.1996.sp021183⟩
Article dans une revue inserm-02448212 v1