Sahil Adriouch

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Adeno‐associated viral vectors encoding anti‐P2X7 nanobodies reduce graft‐versus‐host disease in a humanised mouse model

Amal Elhage , Janna H Hadaya , Chloe Sligar , Debbie Watson , Sahil Adriouch et al.

Clinical and Translational Immunology, 2025, 14 (11), pp.e70061. ⟨10.1002/cti2.70061⟩

Article dans une revue hal-05352884v1

Macrophage expression of P2X7 controls autoimmune uveitis

Paul-Alexandre Déchelle-Marquet , Yueshen Che , Camille Roux , Frédéric Blond , Kaitryn Ronning et al.

Journal of Neuroinflammation, 2025, 22 (1), pp.212. ⟨10.1186/s12974-025-03529-w⟩

Article dans une revue hal-05337677v1
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Administration of an AAV vector coding for a P2X7-blocking nanobody-based biologic ameliorates colitis in mice

Catalina Abad , Mélanie Demeules , Charlotte Guillou , Henri Gondé , Rachid Zoubairi et al.

Journal of Nanobiotechnology, 2024, 22 (1), pp.27. ⟨10.1186/s12951-023-02285-4⟩

Article dans une revue hal-04739785v1

Administration of an AAV vector coding for a P2X7-blocking nanobody-based biologic ameliorates colitis in mice

Catalina Abad , Mélanie Demeules , Charlotte Guillou , Henri Gondé , Rachid Zoubairi et al.

Journal of Nanobiotechnology, 2024, 22 (1), pp.27. ⟨10.1186/s12951-023-02285-4⟩

Article dans une revue hal-04616047v1

The Angiogenesis Inhibitor Isthmin-1 (ISM1) Is Overexpressed in Experimental Models of Glomerulopathy and Impairs the Viability of Podocytes

Virgilia Sahiri , Jonathan Caron , Elena Roger , Christophe Desterke , Khalil Ghachem et al.

International Journal of Molecular Sciences, 2023, 24 (3), pp.2723. ⟨10.3390/ijms24032723⟩

Article dans une revue hal-04023018v1

Capsid-modified adeno-associated virus vectors as novel vaccine platform for cancer immunotherapy

Ann-Christin Franke , Romain Hardet , Lisa Prager , Martin Bentler , Mélanie Demeules et al.

Molecular Therapy - Methods and Clinical Development, 2023, 29, pp.238-253. ⟨10.1016/j.omtm.2023.03.010⟩

Article dans une revue hal-05148970v1

Animal Models for the Investigation of P2X7 Receptors

Ronald Sluyter , Sahil Adriouch , Stephen Fuller , Annette Nicke , Reece Sophocleous et al.

International Journal of Molecular Sciences, 2023, 24 (9), pp.8225. ⟨10.3390/ijms24098225⟩

Article dans une revue hal-05148952v1

Understanding and Tackling Immune Responses to Adeno-Associated Viral Vectors

Helena Costa-Verdera , Carmen Unzu , Erika Valeri , Sahil Adriouch , Gloria González Aseguinolaza et al.

Human Gene Therapy, 2023, 34 (17-18), pp.836-852. ⟨10.1089/hum.2023.119⟩

Article dans une revue hal-05148959v1

Modifying immune responses to adeno-associated virus vectors by capsid engineering

Martin Bentler , Romain Hardet , Moritz Ertelt , Daniela Rudolf , Dorota Kaniowska et al.

Molecular Therapy - Methods and Clinical Development, 2023, 30, pp.576-592. ⟨10.1016/j.omtm.2023.08.015⟩

Article dans une revue hal-04659638v1

Enhanced Transduction of P2X7-Expressing Cells with Recombinant rAAV Vectors

Anna Marei Mann , Waldemar Schäfer , Sahil Adriouch , Kathleen Börner , Dirk Grimm et al.

Methods Mol Biol. , 2022, Methods in Molecular Biology, 2510, pp.129-144. ⟨10.1007/978-1-0716-2384-8_7⟩

Article dans une revue hal-05150095v1

Evaluation of nanobody-based biologics targeting purinergic checkpoints in tumor models in vivo

Mélanie Demeules , Allan Scarpitta , Romain Hardet , Henri Gondé , Catalina Abad et al.

Frontiers in Immunology, 2022, 13, ⟨10.3389/fimmu.2022.1012534⟩

Article dans une revue hal-05150132v1

Development of Antibody and Nanobody Tools for P2X7

Tobias Stähler , Welbeck Danquah , Melanie Demeules , Henri Gondé , Romain Hardet et al.

Biomolecules, 2022, Methods in Molecular Biology, 2510 (7), pp.99-127. ⟨10.1007/978-1-0716-2384-8_6⟩

Article dans une revue hal-05150093v1

Effective targeting of microglial P2X7 following intracerebroventricular delivery of nanobodies and nanobody-encoding AAVs

Carolina Pinto-Espinoza , Charlotte Guillou , Björn Rissiek , Maximilian Wilmes , Ehsan Javidi et al.

Frontiers in Pharmacology, 2022, 13, ⟨10.3389/fphar.2022.1029236⟩

Article dans une revue hal-05150133v1
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Keeping Cell Death Alive: An Introduction into the French Cell Death Research Network

Gabriel Ichim , Benjamin Gibert , Sahil Adriouch , Catherine Brenner , Nathalie Davoust et al.

Biomolecules, 2022, 12 (7), pp.901. ⟨10.3390/biom12070901⟩

Article dans une revue hal-03711790v1

ASC nanobodies to counteract the consequences of inflammasome activation

Sahil Adriouch , Pablo Pelegrin

EMBO Molecular Medicine, 2022, 14 (6), ⟨10.15252/emmm.202216087⟩

Article dans une revue hal-05150099v1
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Pyroptotic and Necroptotic Cell Death in the Tumor Microenvironment and Their Potential to Stimulate Anti-Tumor Immune Responses

Allan Scarpitta , Ulrich Hacker , Hildegard Büning , Olivier Boyer , Sahil Adriouch

Frontiers in Oncology, 2021, 11, pp.731598. ⟨10.3389/fonc.2021.731598⟩

Article dans une revue (article de synthèse) hal-05165892v1

Generation of Pure Highly Functional Human Anti-Tumor Specific Cytotoxic T Lymphocytes With Stem Cell-Like Memory Features for Melanoma Immunotherapy

Mohamad Hamieh , Jean-François Chatillon , Estelle Dupel , Florence Bayeux , Emilie Fauquembergue et al.

Frontiers in Immunology, 2021, 12, ⟨10.3389/fimmu.2021.674276⟩

Article dans une revue hal-05165913v1

A Methodological Approach Using rAAV Vectors Encoding Nanobody-Based Biologics to Evaluate ARTC2.2 and P2X7 In Vivo

Henri Gondé , Mélanie Demeules , Romain Hardet , Allan Scarpitta , Marten Junge et al.

Frontiers in Immunology, 2021, 12 (1), pp.327-330. ⟨10.3389/fimmu.2021.704408⟩

Article dans une revue hal-05165906v1
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A small-molecule P2RX7 activator promotes anti-tumor immune responses and sensitizes lung tumor to immunotherapy

Laetitia Douguet , Serena Janho Dit Hreich , Jonathan Benzaquen , Laetitia Seguin , Thierry Juhel et al.

Nature Communications, 2021, 12 (1), p.653. ⟨10.1038/s41467-021-20912-2⟩

Article dans une revue hal-03126997v1

Evaluation of P2X7 Receptor Function in Tumor Contexts Using rAAV Vector and Nanobodies (AAVnano)

Mélanie Demeules , Allan Scarpitta , Catalina Abad , Henri Gondé , Romain Hardet et al.

Frontiers in Oncology, 2020, Reviews of Physiology, Biochemistry and Pharmacology, 10, pp.157-176. ⟨10.3389/fonc.2020.01699⟩

Article dans une revue hal-05166020v1

Flow cytometry: An accurate tool for screening P2RX7 modulators

Amélie Barczyk , Hélène Bauderlique‐le Roy , Nathalie Jouy , Nicolas Renault , Audrey Hottin et al.

Cytometry Part A, 2020, Online ahead of print. ⟨10.1002/cyto.a.24287⟩

Article dans une revue inserm-03108965v1

Lymphatic and Immune Cell Cross-Talk Regulates Cardiac Recovery After Experimental Myocardial Infarction

Mahmoud Houssari , Anais Dumesnil , Virginie Tardif , Riikka Kivelä , Nathalie Pizzinat et al.

Arteriosclerosis, Thrombosis, and Vascular Biology, 2020, 40 (7), pp.1722-1737. ⟨10.1161/ATVBAHA.120.314370⟩

Article dans une revue hal-03553406v1
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Vector uncoating limits adeno-associated viral vector-mediated transduction of human dendritic cells and vector immunogenicity

Axel Rossi , Léa Dupaty , Ludovic Aillot , Liang Zhang , Célia Gallien et al.

Scientific Reports, 2019, 9 (1), ⟨10.1038/s41598-019-40071-1⟩

Article dans une revue hal-02375623v1

Nanobody-Enhanced Targeting of AAV Gene Therapy Vectors

Anna Marei Eichhoff , Kathleen Börner , Birte Albrecht , Waldemar Schäfer , Natalie Baum et al.

Molecular Therapy - Methods and Clinical Development, 2019, 15, pp.211-220. ⟨10.1016/j.omtm.2019.09.003⟩

Article dans une revue hal-02376242v1
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Pyroglutamide-Based P2X7 Receptor Antagonists Targeting Inflammatory Bowel Disease

Germain Homerin , Davy Baudelet , Pierrick Dufrénoy , Benoît Rigo , Régis Millet et al.

Journal of Medicinal Chemistry, 2019, Women in Medicinal Chemistry, 63 (5), pp.2074-2094. ⟨10.1021/acs.jmedchem.9b00584⟩

Article dans une revue hal-03093950v1

AMPK Activation of PGC-1α/NRF-1-Dependent SELENOT Gene Transcription Promotes PACAP-Induced Neuroendocrine Cell Differentiation Through Tolerance to Oxidative Stress

Houssni Abid , Dorthe Cartier , Abdallah Hamieh , Anne-Marie François-Bellan , Christine Bucharles et al.

Molecular Neurobiology, 2019, 56 (6), pp.4086-4101. ⟨10.1007/s12035-018-1352-x⟩

Article dans une revue hal-02375763v1
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P2X7 receptor induces mitochondrial failure in monocytes and compromises NLRP3 inflammasome activation during sepsis

Juan José Martínez-García , Helios Martínez-Banaclocha , Diego Angosto-Bazarra , Carlos de Torre-Minguela , Alberto Baroja-Mazo et al.

Nature Communications, 2019, 10 (1), ⟨10.1038/s41467-019-10626-x⟩

Article dans une revue hal-02376247v1

Contribution of genotoxic anticancer treatments to the development of multiple primary tumours in the context of germline TP53 mutations.

Edwige Kasper , Emilie Angot , Elodie Colasse , Lionel Nicol , Jean-Christophe Sabourin et al.

European Journal of Cancer, 2018, ⟨10.1016/j.ejca.2018.06.011⟩

Article dans une revue hal-02355640v1

Contribution of genotoxic anticancer treatments to the development of multiple primary tumours in the context of germline TP53 mutations

Edwige Kasper , Émilie Angot , Elodie Colasse , Lionel Nicol , Jean-Christophe Sabourin et al.

European Journal of Cancer, 2018, 101, pp.254-262. ⟨10.1016/j.ejca.2018.06.011⟩

Article dans une revue hal-02375757v1
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Ecto-ADP-ribosyltransferase ARTC2.1 functionally modulates FcγR1 and FcγR2B on murine microglia

Björn Rissiek , Stephan Menzel , Mario Leutert , Maike Cordes , Sarah Behr et al.

Scientific Reports, 2017, 7 (1), ⟨10.1038/s41598-017-16613-w⟩

Article dans une revue hal-02375773v1
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Receptor Activator of NF-κB Orchestrates Activation of Antiviral Memory CD8 T Cells in the Spleen Marginal Zone

Mohamed Habbeddine , Christophe Verthuy , Olivia Rastoin , Lionel Chasson , Magali Bebien et al.

Cell Reports, 2017, 21 (9), pp.2515-2527. ⟨10.1016/j.celrep.2017.10.111⟩

Article dans une revue hal-02376107v1

Clonal Proliferation and Stochastic Pruning Orchestrate Lymph Node Vasculature Remodeling

Isabelle Mondor , Audrey Jorquera , Cynthia Sene , Sahil Adriouch , Ralf heinrich Adams et al.

Immunity, 2016, 45 (4), pp.877-888. ⟨10.1016/j.immuni.2016.09.017⟩

Article dans une revue hal-02376120v1

HACE1 is a putative tumor suppressor gene in B-cell lymphomagenesis and is down-regulated by both deletion and epigenetic alterations

Abdelilah Bouzelfen , Marion Alcantara , Hafid Kora , Jean-Michel Picquenot , Philippe Bertrand et al.

Leukemia Research, 2016, 45, pp.90-100. ⟨10.1016/j.leukres.2016.04.007⟩

Article dans une revue istex hal-02329894v1
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Induction of hematopoietic Microchimerism by gene-Modified BMT elicits antigen-specific B and T cell Unresponsiveness toward gene Therapy Products

Jérémie Martinet , Gwladys Bourdenet , Amine Meliani , Laetitia L Jean , Sahil Adriouch et al.

Frontiers in Immunology, 2016, 7, pp.360. ⟨10.3389/fimmu.2016.00360⟩

Article dans une revue hal-01378432v1

CRISPR-Barcoding for Intratumor Genetic Heterogeneity Modeling and Functional Analysis of Oncogenic Driver Mutations

Alexis Guernet , Sathish kumar Mungamuri , Dorthe Cartier , Ravi Sachidanandam , Anitha Jayaprakash et al.

Molecular Cell, 2016, 63 (3), pp.526-538. ⟨10.1016/j.molcel.2016.06.017⟩

Article dans une revue hal-02376161v1
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Oral-tolerization Prevents Immune Responses and Improves Transgene Persistence Following AAV-mediated gene transfer

Romain Hardet , Benjamin Chevalier , Léa Dupaty , Yassine Naïmi , Gaetan Riou et al.

Molecular Therapy, 2016, 24 (1), pp.87-95. ⟨10.1038/mt.2015.146⟩

Article dans une revue hal-02376152v1
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P2X7 on Mouse T Cells: One Channel, Many Functions

Björn Rissiek , Friedrich Haag , Olivier Boyer , Friedrich Koch-Nolte , Sahil Adriouch

Frontiers in Immunology, 2015, 6, pp.204. ⟨10.3389/fimmu.2015.00204⟩

Article dans une revue hal-02376237v1

Genetic and Pharmacological Inactivation of the Purinergic P2RX7 Receptor Dampens Inflammation but Increases Tumor Incidence in a Mouse Model of Colitis-Associated Cancer

Paul Hofman , Julien Cherfils-Vicini , Marie Bazin , Marius Ilie , Thierry Juhel et al.

Cancer Research, 2015, 75 (5), pp.835-845. ⟨10.1158/0008-5472.CAN-14-1778⟩

Article dans une revue hal-04616077v1

Evaluation and comparison of three different separation techniques for analysis of retroamide enantiomers and their biological evaluation against h-P2X7 receptor

Tiphaine Rogez Florent , Davy Baudelet , Christophe Furman , Alina Ghinet , Xavier Dezitter et al.

Journal of Chromatography B - Analytical Technologies in the Biomedical and Life Sciences, 2015, 986-987, pp.35-43. ⟨10.1016/j.jchromb.2015.02.001⟩

Article dans une revue istex hal-02178095v1

Intrinsic Transgene Immunogenicity Gears CD8+ T-cell Priming After rAAV-Mediated Muscle Gene Transfer

Maxime Carpentier , Stéphanie Lorain , Pascal Chappert , Mélanie Lalfer , Romain Hardet et al.

Molecular Therapy, 2015, 23 (4), pp.697-706. ⟨10.1038/mt.2014.235⟩

Article dans une revue hal-02407918v1
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Role of M2-like macrophage recruitment during angiogenic growth factor therapy

Virginie Barbay , Mahmoud Houssari , Malik Mekki , Sebastien Banquet , Jean-Paul Henry et al.

Angiogenesis, 2015, 18 (2), pp.191-200. ⟨10.1007/s10456-014-9456-z⟩

Article dans une revue inserm-02296563v1

Prophylactic Injection of Recombinant Alpha-Enolase Reduces Arthritis Severity in the Collagen-Induced Arthritis Mice Model

Clément Guillou , Céline Derambure , Manuel Fréret , Mathieu Verdet , Gilles Avenel et al.

PLoS ONE, 2015, 10 (8), pp.e0136359. ⟨10.1371/journal.pone.0136359⟩

Article dans une revue hal-02376205v1
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Tuning IL-2 signaling by ADP-ribosylation of CD25

Sophie Teege , Alexander Hann , Maria Miksiewicz , Cary Macmillan , Björn Rissiek et al.

Scientific Reports, 2015, 5 (1), ⟨10.1038/srep08959⟩

Article dans une revue hal-02376180v1

A new genotoxicity assay based on p53 target gene induction

Yasmine Zerdoumi , Edwige Kasper , Flavie Soubigou , S. Adriouch , Gaëlle Bougeard et al.

Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 2015, 789-790, pp.28-35. ⟨10.1016/j.mrgentox.2015.05.010⟩

Article dans une revue hal-02356415v1

Genetic and Pharmacological Inactivation of the Purinergic P2RX7 Receptor Dampens Inflammation but Increases Tumor Incidence in a Mouse Model of Colitis-Associated Cancer

P. Hofman , J. Cherfils-Vicini , M. Bazin , M. Ilie , T. Juhel et al.

Cancer Research, 2015, 75 (5), pp.835-845. ⟨10.1158/0008-5472.CAN-14-1778⟩

Article dans une revue hal-02377448v1
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Role of Toll-like Receptors 2 and 4 in Mediating Endothelial Dysfunction and Arterial Remodeling in Primary Arterial Antiphospholipid Syndrome

Ygal Benhamou , Jeremy Bellien , Guillaume Armengol , Ebba Brakenhielm , Sahil Adriouch et al.

Arthritis & rheumatology, 2014, 66 (11), pp.3210-3220. ⟨10.1002/art.38785⟩

Article dans une revue inserm-02296566v1

ADP-Ribosylation of P2X7: A Matter of Life and Death for Regulatory T Cells and Natural Killer T Cells

Björn Rissiek , Friedrich Haag , Olivier Boyer , Friedrich Koch-Nolte , Sahil Adriouch

Current Topics in Microbiology and Immunology, 2014, pp.107-126. ⟨10.1007/82_2014_420⟩

Article dans une revue hal-02377446v1

Mechanical-Stretch of C2C12 Myoblasts Inhibits Expression of Toll-Like Receptor 3 (TLR3) and of Autoantigens Associated with Inflammatory Myopathies

Rong Chen , Liqiang Feng , Mo Ruan , Xinghui Liu , Sahil Adriouch et al.

PLoS ONE, 2013, 8 (11), pp.e79930. ⟨10.1371/journal.pone.0079930⟩

Article dans une revue hal-05224665v1

Overexpression of MHC Class I in Muscle of Lymphocyte-Deficient Mice Causes a Severe Myopathy with Induction of the Unfolded Protein Response

Manuel Fréret , Laurent Drouot , Antoine Obry , Sandra Ahmed-Lacheheb , Claire Dauly et al.

American Journal of Pathology, 2013, 183 (3), pp.893-904. ⟨10.1016/j.ajpath.2013.06.003⟩

Article dans une revue hal-05224659v1
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Myoinjury transiently activates muscle antigen-specific CD8+ T cells in lymph nodes in a mouse model.

Hua Liao , Emilie Franck , Manuel Fréret , Sahil Adriouch , Yasmine Baba-Amer et al.

Arthritis and Rheumatism, 2012, 64 (10), pp.3441-51. ⟨10.1002/art.34551⟩

Article dans une revue inserm-00750113v1

Extracellular NAD+: a danger signal hindering regulatory T cells

Sahil Adriouch , Friedrich Haag , Olivier Boyer , Michel Seman , Friedrich Koch-Nolte

Microbes and Infection, 2012, 14 (14), pp.1284-1292. ⟨10.1016/j.micinf.2012.05.011⟩

Article dans une revue istex hal-05224653v1

Alternative Splicing of the N-Terminal Cytosolic and Transmembrane Domains of P2X7 Controls Gating of the Ion Channel by ADP-Ribosylation

Nicole Schwarz , Laurent Drouot , Annette Nicke , Ralf Fliegert , Olivier Boyer et al.

PLoS ONE, 2012, 7 (7), pp.e41269. ⟨10.1371/journal.pone.0041269⟩

Article dans une revue hal-05224657v1

Immunological Tolerance to Muscle Autoantigens Involves Peripheral Deletion of Autoreactive CD8+ T Cells

Emilie Franck , Carole Bonneau , Laetitia Jean , Jean-Paul Henry , Yann Lacoume et al.

PLoS ONE, 2012, 7 (5), pp.e36444. ⟨10.1371/journal.pone.0036444⟩

Article dans une revue hal-05224649v1

Myoinjury transiently activates muscle antigen–specific CD8+ T cells in lymph nodes in a mouse model

Hua Liao , Emilie Franck , Manuel Fréret , Sahil Adriouch , Yasmine Baba-Amer et al.

Arthritis and Rheumatism, 2012, 64 (10), pp.3441-3451. ⟨10.1002/art.34551⟩

Article dans une revue hal-05224656v1

Improved Immunological Tolerance Following Combination Therapy with CTLA-4/Ig and AAV-Mediated PD-L1/2 Muscle Gene Transfer

Sahil Adriouch , Emilie Franck , Laurent Drouot , Carole Bonneau , Nelly Jolinon et al.

Frontiers in Microbiology, 2011, 2, ⟨10.3389/fmicb.2011.00199⟩

Article dans une revue hal-05224646v1

Extracellular NAD+ shapes the Foxp3+ regulatory T cell compartment through the ART2–P2X7 pathway

Sandra Hubert , Björn Rissiek , Katjana Klages , Jochen Huehn , Tim Sparwasser et al.

Journal of Experimental Medicine, 2010, 207 (12), pp.2561-2568. ⟨10.1084/jem.20091154⟩

Article dans une revue hal-05224572v1

Single domain antibodies: promising experimental and therapeutic tools in infection and immunity

Janusz Wesolowski , Vanina Alzogaray , Jan Reyelt , Mandy Unger , Karla Juarez et al.

Medical Microbiology and Immunology, 2009, 198 (3), pp.157-174. ⟨10.1007/s00430-009-0116-7⟩

Article dans une revue hal-05224566v1

NAD+ and ATP Released from Injured Cells Induce P2X7-Dependent Shedding of CD62L and Externalization of Phosphatidylserine by Murine T Cells

Sahil Adriouch , Felix Scheuplein , Robert Bähring , Michel Seman , Olivier Boyer et al.

Journal of Immunology, 2009, 182 (5), pp.2898-2908. ⟨10.4049/jimmunol.0801711⟩

Article dans une revue hal-05224620v1

Activation of the P2X7 ion channel by soluble and covalently bound ligands

Nicole Schwarz , Ralf Fliegert , Sahil Adriouch , Michel Seman , Andreas Guse et al.

Purinergic Signalling, 2009, 5 (2), pp.139-149. ⟨10.1007/s11302-009-9135-5⟩

Article dans une revue hal-05224628v1

ADP‐ribosylation of membrane proteins: Unveiling the secrets of a crucial regulatory mechanism in mammalian cells

Friedrich Koch-Nolte , Sahil Adriouch , Peter Bannas , Christian Krebs , Felix Scheuplein et al.

Annals of Medicine, 2009, 38 (3), pp.188-199. ⟨10.1080/07853890600655499⟩

Article dans une revue hal-05224603v1

Monitoring the expression of purinoceptors and nucleotide-metabolizing ecto-enzymes with antibodies directed against proteins in native conformation

Felix Scheuplein , Nicole Schwarz , Sahil Adriouch , Christian Krebs , Peter Bannas et al.

Journal of Immunology, 2009, 182 (5), pp.2898-2908. ⟨10.1007/s11302-007-9084-9⟩

Article dans une revue hal-05224618v1

Characterisation of the R276A gain-of-function mutation in the ectodomain of murine P2X7

Nicole Schwarz , Ralf Fliegert , Sahil Adriouch , Michel Seman , Andreas Guse et al.

Purinergic Signalling, 2009, 5 (2), pp.151-161. ⟨10.1007/s11302-009-9134-6⟩

Article dans une revue hal-05224621v1

Cutting Edge: CD4-Independent Development of Functional FoxP3+ Regulatory T Cells

Céline Blache , Sahil Adriouch , Sébastien Calbo , Laurent Drouot , Sophie Dulauroy et al.

Journal of Immunology, 2009, 183 (7), pp.4182-4186. ⟨10.4049/jimmunol.0901678⟩

Article dans une revue hal-05224640v1

ADP‐ribosylation at R125 gates the P2X7 ion channel by presenting a covalent ligand to its nucleotide binding site

Sahil Adriouch , Peter Bannas , Nicole Schwarz , Ralf Fliegert , Andreas Guse et al.

FASEB Journal, 2007, 22 (3), pp.861-869. ⟨10.1096/fj.07-9294com⟩

Article dans une revue hal-05224610v1

NAD+ Released during Inflammation Participates in T Cell Homeostasis by Inducing ART2-Mediated Death of Naive T Cells In Vivo

Sahil Adriouch , Sandra Hubert , Severine Pechberty , Friedrich Koch-Nolte , Friedrich Haag et al.

Journal of Immunology, 2007, 179 (1), pp.186-194. ⟨10.4049/jimmunol.179.1.186⟩

Article dans une revue hal-05224606v1

Extracellular NAD and ATP: Partners in immune cell modulation

Friedrich Haag , Sahil Adriouch , Anette Braß , Caroline Jung , Sina Möller et al.

Purinergic Signalling, 2007, 3 (1-2), pp.71. ⟨10.1007/s11302-006-9038-7⟩

Article dans une revue hal-05224614v1

Probing the expression and function of the P2X7 purinoceptor with antibodies raised by genetic immunization

Sahil Adriouch , Gudrun Dubberke , Philip Diessenbacher , François Rassendren , Michel Seman et al.

Cellular Immunology, 2005, 236 (1-2), pp.72-77. ⟨10.1016/j.cellimm.2005.08.011⟩

Article dans une revue istex hal-05224599v1

Probing the expression and function of the P2X7 purinoceptor with antibodies raised by genetic immunization

S. Adriouch , G. Dubberke , P. Diessenbacher , François Rassendren , M. Seman et al.

Cellular Immunology, 2005, 236, pp.72-77. ⟨10.1016/j.cellimm.2005.08.011⟩

Article dans une revue istex hal-00016889v1

CD38 Controls ADP-Ribosyltransferase-2-Catalyzed ADP-Ribosylation of T Cell Surface Proteins

Christian Krebs , Sahil Adriouch , Fenja Braasch , Wolfgang Koestner , Edward Leiter et al.

Journal of Immunology, 2005, 174 (6), pp.3298-3305. ⟨10.4049/jimmunol.174.6.3298⟩

Article dans une revue hal-05224591v1

Activity and specificity of toxin-related mouse T cell ecto–ADP-ribosyltransferase ART2.2 depends on its association with lipid rafts

Peter Bannas , Sahil Adriouch , Sarah Kahl , Fenja Braasch , Friedrich Haag et al.

Blood, 2005, 105 (9), pp.3663-3670. ⟨10.1182/blood-2004-08-3325⟩

Article dans une revue hal-05224590v1

Ecto-ADP-Ribosyltransferases (ARTs): Emerging Actors in Cell Communication and Signaling

Michel Seman , Sahil Adriouch , Friedrich Haag , Friedrich Koch-Nolte

Current Medicinal Chemistry, 2004, 11 (7), pp.857-872. ⟨10.2174/0929867043455611⟩

Article dans une revue istex hal-05224583v1

NAD-Induced T Cell Death: ADP-Ribosylation of Cell Surface Proteins by ART2 Activates the Cytolytic P2X7 Purinoceptor

Michel Seman , Sahil Adriouch , Felix Scheuplein , Christian Krebs , Dunja Freese et al.

Immunity, 2003, 19 (4), pp.571-582. ⟨10.1016/s1074-7613(03)00266-8⟩

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Convergent alteration of granulopoiesis, chemotactic activity, and neutrophil apoptosis during mouse selection for high acute inflammatory response

Orlando Ribeiro , Durvanei Maria , Sahil Adriouch , Séverine Pechberty , Wafa Cabrera et al.

Journal of Leukocyte Biology, 2003, 74 (4), pp.497-506. ⟨10.1189/jlb.0103039⟩

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T Cells of Different Developmental Stages Differ in Sensitivity to Apoptosis Induced by Extracellular NAD

Friedrich Haag , Dunja Freese , Felix Scheublein , Wiebke Ohlrogge , Sahil Adriouch et al.

Journal of Immunology Research, 2002, 9 (4), pp.197-202. ⟨10.1080/10446670310001593514⟩

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Cutting Edge: A Natural P451L Mutation in the Cytoplasmic Domain Impairs the Function of the Mouse P2X7 Receptor

Sahil Adriouch , Claudia Dox , Vivienne Welge , Michel Seman , Friedrich Koch-Nolte et al.

Journal of Immunology, 2002, 169 (8), pp.4108-4112. ⟨10.4049/jimmunol.169.8.4108⟩

Article dans une revue hal-05224524v1

Monitoring Expression and Enzyme Activity of Ecto-ARTCs

Stephan Menzel , Sahil Adriouch , Peter Bannas , Friedrich Haag , Friedrich Koch-Nolte

Paul Chang. ADP-ribosylation and NAD+ utilizing enzymes : methods and protocols, Humana Press, pp.167-186, 2018, 978-1-4939-8587-6. ⟨10.1007/978-1-4939-8588-3_11⟩

Chapitre d'ouvrage hal-02375747v1