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Macrophage expression of P2X7 controls autoimmune uveitis
Paul-Alexandre Déchelle-Marquet
,
Yueshen Che
,
Camille Roux
,
Frédéric Blond
,
Kaitryn Ronning
et al.
Article dans une revue
hal-05337677
v1
|
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Administration of an AAV vector coding for a P2X7-blocking nanobody-based biologic ameliorates colitis in mice
Catalina Abad
,
Mélanie Demeules
,
Charlotte Guillou
,
Henri Gondé
,
Rachid Zoubairi
et al.
Article dans une revue
hal-04739785
v1
|
|
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Administration of an AAV vector coding for a P2X7-blocking nanobody-based biologic ameliorates colitis in mice
Catalina Abad
,
Mélanie Demeules
,
Charlotte Guillou
,
Henri Gondé
,
Rachid Zoubairi
et al.
Article dans une revue
hal-04616047
v1
|
|
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Animal Models for the Investigation of P2X7 Receptors
Ronald Sluyter
,
Sahil Adriouch
,
Stephen Fuller
,
Annette Nicke
,
Reece Sophocleous
et al.
Article dans une revue
hal-05148952
v1
|
|
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Capsid-modified adeno-associated virus vectors as novel vaccine platform for cancer immunotherapy
Ann-Christin Franke
,
Romain Hardet
,
Lisa Prager
,
Martin Bentler
,
Mélanie Demeules
et al.
Article dans une revue
hal-05148970
v1
|
|
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The Angiogenesis Inhibitor Isthmin-1 (ISM1) Is Overexpressed in Experimental Models of Glomerulopathy and Impairs the Viability of Podocytes
Virgilia Sahiri
,
Jonathan Caron
,
Elena Roger
,
Christophe Desterke
,
Khalil Ghachem
et al.
Article dans une revue
hal-04023018
v1
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Understanding and Tackling Immune Responses to Adeno-Associated Viral Vectors
Helena Costa-Verdera
,
Carmen Unzu
,
Erika Valeri
,
Sahil Adriouch
,
Gloria González Aseguinolaza
et al.
Article dans une revue
hal-05148959
v1
|
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Modifying immune responses to adeno-associated virus vectors by capsid engineering
Martin Bentler
,
Romain Hardet
,
Moritz Ertelt
,
Daniela Rudolf
,
Dorota Kaniowska
et al.
Article dans une revue
hal-04659638
v1
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Effective targeting of microglial P2X7 following intracerebroventricular delivery of nanobodies and nanobody-encoding AAVs
Carolina Pinto-Espinoza
,
Charlotte Guillou
,
Björn Rissiek
,
Maximilian Wilmes
,
Ehsan Javidi
et al.
Article dans une revue
hal-05150133
v1
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Development of Antibody and Nanobody Tools for P2X7
Tobias Stähler
,
Welbeck Danquah
,
Melanie Demeules
,
Henri Gondé
,
Romain Hardet
et al.
Article dans une revue
hal-05150093
v1
|
|
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Keeping Cell Death Alive: An Introduction into the French Cell Death Research Network
Gabriel Ichim
,
Benjamin Gibert
,
Sahil Adriouch
,
Catherine Brenner
,
Nathalie Davoust
et al.
Article dans une revue
hal-03711790
v1
|
|
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ASC nanobodies to counteract the consequences of inflammasome activation
Sahil Adriouch
,
Pablo Pelegrin
Article dans une revue
hal-05150099
v1
|
|
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Enhanced Transduction of P2X7-Expressing Cells with Recombinant rAAV Vectors
Anna Marei Mann
,
Waldemar Schäfer
,
Sahil Adriouch
,
Kathleen Börner
,
Dirk Grimm
et al.
Article dans une revue
hal-05150095
v1
|
|
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Evaluation of nanobody-based biologics targeting purinergic checkpoints in tumor models in vivo
Mélanie Demeules
,
Allan Scarpitta
,
Romain Hardet
,
Henri Gondé
,
Catalina Abad
et al.
Article dans une revue
hal-05150132
v1
|
|
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A small-molecule P2RX7 activator promotes anti-tumor immune responses and sensitizes lung tumor to immunotherapy
Laetitia Douguet
,
Serena Janho Dit Hreich
,
Jonathan Benzaquen
,
Laetitia Seguin
,
Thierry Juhel
et al.
Article dans une revue
hal-03126997
v1
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Pyroptotic and Necroptotic Cell Death in the Tumor Microenvironment and Their Potential to Stimulate Anti-Tumor Immune Responses
Allan Scarpitta
,
Ulrich Hacker
,
Hildegard Büning
,
Olivier Boyer
,
Sahil Adriouch
Article dans une revue
hal-05165892
v1
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|
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Generation of Pure Highly Functional Human Anti-Tumor Specific Cytotoxic T Lymphocytes With Stem Cell-Like Memory Features for Melanoma Immunotherapy
Mohamad Hamieh
,
Jean-François Chatillon
,
Estelle Dupel
,
Florence Bayeux
,
Emilie Fauquembergue
et al.
Article dans une revue
hal-05165913
v1
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|
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A Methodological Approach Using rAAV Vectors Encoding Nanobody-Based Biologics to Evaluate ARTC2.2 and P2X7 In Vivo
Henri Gondé
,
Mélanie Demeules
,
Romain Hardet
,
Allan Scarpitta
,
Marten Junge
et al.
Article dans une revue
hal-05165906
v1
|
|
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Lymphatic and Immune Cell Cross-Talk Regulates Cardiac Recovery After Experimental Myocardial Infarction
Mahmoud Houssari
,
Anais Dumesnil
,
Virginie Tardif
,
Riikka Kivelä
,
Nathalie Pizzinat
et al.
Article dans une revue
hal-03553406
v1
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|
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Evaluation of P2X7 Receptor Function in Tumor Contexts Using rAAV Vector and Nanobodies (AAVnano)
Mélanie Demeules
,
Allan Scarpitta
,
Catalina Abad
,
Henri Gondé
,
Romain Hardet
et al.
Article dans une revue
hal-05166020
v1
|
|
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Flow cytometry: An accurate tool for screening P2RX7 modulators
Amélie Barczyk
,
Hélène Bauderlique‐le Roy
,
Nathalie Jouy
,
Nicolas Renault
,
Audrey Hottin
et al.
Article dans une revue
inserm-03108965
v1
|
|
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AMPK Activation of PGC-1α/NRF-1-Dependent SELENOT Gene Transcription Promotes PACAP-Induced Neuroendocrine Cell Differentiation Through Tolerance to Oxidative Stress
Houssni Abid
,
Dorthe Cartier
,
Abdallah Hamieh
,
Anne-Marie François-Bellan
,
Christine Bucharles
et al.
Article dans une revue
hal-02375763
v1
|
|
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Nanobody-Enhanced Targeting of AAV Gene Therapy Vectors
Anna Marei Eichhoff
,
Kathleen Börner
,
Birte Albrecht
,
Waldemar Schäfer
,
Natalie Baum
et al.
Article dans une revue
hal-02376242
v1
|
|
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Pyroglutamide-Based P2X7 Receptor Antagonists Targeting Inflammatory Bowel Disease
Germain Homerin
,
Davy Baudelet
,
Pierrick Dufrénoy
,
Benoît Rigo
,
Régis Millet
et al.
Article dans une revue
hal-03093950
v1
|
|
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P2X7 receptor induces mitochondrial failure in monocytes and compromises NLRP3 inflammasome activation during sepsis
Juan José Martínez-García
,
Helios Martínez-Banaclocha
,
Diego Angosto-Bazarra
,
Carlos de Torre-Minguela
,
Alberto Baroja-Mazo
et al.
Article dans une revue
hal-02376247
v1
|
|
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Vector uncoating limits adeno-associated viral vector-mediated transduction of human dendritic cells and vector immunogenicity
Axel Rossi
,
Léa Dupaty
,
Ludovic Aillot
,
Liang Zhang
,
Célia Gallien
et al.
Article dans une revue
hal-02375623
v1
|
|
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Contribution of genotoxic anticancer treatments to the development of multiple primary tumours in the context of germline TP53 mutations.
Edwige Kasper
,
Emilie Angot
,
Elodie Colasse
,
Lionel Nicol
,
Jean-Christophe Sabourin
et al.
Article dans une revue
hal-02355640
v1
|
|
|
Contribution of genotoxic anticancer treatments to the development of multiple primary tumours in the context of germline TP53 mutations
Edwige Kasper
,
Émilie Angot
,
Elodie Colasse
,
Lionel Nicol
,
Jean-Christophe Sabourin
et al.
Article dans une revue
hal-02375757
v1
|
|
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Ecto-ADP-ribosyltransferase ARTC2.1 functionally modulates FcγR1 and FcγR2B on murine microglia
Björn Rissiek
,
Stephan Menzel
,
Mario Leutert
,
Maike Cordes
,
Sarah Behr
et al.
Article dans une revue
hal-02375773
v1
|
|
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Receptor Activator of NF-κB Orchestrates Activation of Antiviral Memory CD8 T Cells in the Spleen Marginal Zone
Mohamed Habbeddine
,
Christophe Verthuy
,
Olivia Rastoin
,
Lionel Chasson
,
Magali Bebien
et al.
Article dans une revue
hal-02376107
v1
|
|
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CRISPR-Barcoding for Intratumor Genetic Heterogeneity Modeling and Functional Analysis of Oncogenic Driver Mutations
Alexis Guernet
,
Sathish kumar Mungamuri
,
Dorthe Cartier
,
Ravi Sachidanandam
,
Anitha Jayaprakash
et al.
Article dans une revue
hal-02376161
v1
|
|
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Oral-tolerization Prevents Immune Responses and Improves Transgene Persistence Following AAV-mediated gene transfer
Romain Hardet
,
Benjamin Chevalier
,
Léa Dupaty
,
Yassine Naïmi
,
Gaetan Riou
et al.
Article dans une revue
hal-02376152
v1
|
|
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HACE1 is a putative tumor suppressor gene in B-cell lymphomagenesis and is down-regulated by both deletion and epigenetic alterations
Abdelilah Bouzelfen
,
Marion Alcantara
,
Hafid Kora
,
Jean-Michel Picquenot
,
Philippe Bertrand
et al.
Article dans une revue
hal-02329894
v1
|
|
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Induction of hematopoietic Microchimerism by gene-Modified BMT elicits antigen-specific B and T cell Unresponsiveness toward gene Therapy Products
Jérémie Martinet
,
Gwladys Bourdenet
,
Amine Meliani
,
Laetitia L Jean
,
Sahil Adriouch
et al.
Article dans une revue
hal-01378432
v1
|
|
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Clonal Proliferation and Stochastic Pruning Orchestrate Lymph Node Vasculature Remodeling
Isabelle Mondor
,
Audrey Jorquera
,
Cynthia Sene
,
Sahil Adriouch
,
Ralf heinrich Adams
et al.
Article dans une revue
hal-02376120
v1
|
|
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Prophylactic Injection of Recombinant Alpha-Enolase Reduces Arthritis Severity in the Collagen-Induced Arthritis Mice Model
Clément Guillou
,
Céline Derambure
,
Manuel Fréret
,
Mathieu Verdet
,
Gilles Avenel
et al.
Article dans une revue
hal-02376205
v1
|
|
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Role of M2-like macrophage recruitment during angiogenic growth factor therapy
Virginie Barbay
,
Mahmoud Houssari
,
Malik Mekki
,
Sebastien Banquet
,
Jean-Paul Henry
et al.
Article dans une revue
inserm-02296563
v1
|
|
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A new genotoxicity assay based on p53 target gene induction
Yasmine Zerdoumi
,
Edwige Kasper
,
Flavie Soubigou
,
S. Adriouch
,
Gaëlle Bougeard
et al.
Article dans une revue
hal-02356415
v1
|
|
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Tuning IL-2 signaling by ADP-ribosylation of CD25
Sophie Teege
,
Alexander Hann
,
Maria Miksiewicz
,
Cary Macmillan
,
Björn Rissiek
et al.
Article dans une revue
hal-02376180
v1
|
|
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Genetic and Pharmacological Inactivation of the Purinergic P2RX7 Receptor Dampens Inflammation but Increases Tumor Incidence in a Mouse Model of Colitis-Associated Cancer
P. Hofman
,
J. Cherfils-Vicini
,
M. Bazin
,
M. Ilie
,
T. Juhel
et al.
Article dans une revue
hal-02377448
v1
|
|
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Intrinsic Transgene Immunogenicity Gears CD8+ T-cell Priming After rAAV-Mediated Muscle Gene Transfer
Maxime Carpentier
,
Stéphanie Lorain
,
Pascal Chappert
,
Mélanie Lalfer
,
Romain Hardet
et al.
Article dans une revue
hal-02407918
v1
|
|
|
Genetic and Pharmacological Inactivation of the Purinergic P2RX7 Receptor Dampens Inflammation but Increases Tumor Incidence in a Mouse Model of Colitis-Associated Cancer
Paul Hofman
,
Julien Cherfils-Vicini
,
Marie Bazin
,
Marius Ilie
,
Thierry Juhel
et al.
Article dans une revue
hal-04616077
v1
|
|
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P2X7 on Mouse T Cells: One Channel, Many Functions
Björn Rissiek
,
Friedrich Haag
,
Olivier Boyer
,
Friedrich Koch-Nolte
,
Sahil Adriouch
Article dans une revue
hal-02376237
v1
|
|
|
Evaluation and comparison of three different separation techniques for analysis of retroamide enantiomers and their biological evaluation against h-P2X7 receptor
Tiphaine Rogez Florent
,
Davy Baudelet
,
Christophe Furman
,
Alina Ghinet
,
Xavier Dezitter
et al.
Article dans une revue
hal-02178095
v1
|
|
|
ADP-Ribosylation of P2X7: A Matter of Life and Death for Regulatory T Cells and Natural Killer T Cells
Björn Rissiek
,
Friedrich Haag
,
Olivier Boyer
,
Friedrich Koch-Nolte
,
Sahil Adriouch
Article dans une revue
hal-02377446
v1
|
|
|
Role of Toll-like Receptors 2 and 4 in Mediating Endothelial Dysfunction and Arterial Remodeling in Primary Arterial Antiphospholipid Syndrome
Ygal Benhamou
,
Jeremy Bellien
,
Guillaume Armengol
,
Ebba Brakenhielm
,
Sahil Adriouch
et al.
Article dans une revue
inserm-02296566
v1
|
|
|
Mechanical-Stretch of C2C12 Myoblasts Inhibits Expression of Toll-Like Receptor 3 (TLR3) and of Autoantigens Associated with Inflammatory Myopathies
Rong Chen
,
Liqiang Feng
,
Mo Ruan
,
Xinghui Liu
,
Sahil Adriouch
et al.
Article dans une revue
hal-05224665
v1
|
|
|
Overexpression of MHC Class I in Muscle of Lymphocyte-Deficient Mice Causes a Severe Myopathy with Induction of the Unfolded Protein Response
Manuel Fréret
,
Laurent Drouot
,
Antoine Obry
,
Sandra Ahmed-Lacheheb
,
Claire Dauly
et al.
Article dans une revue
hal-05224659
v1
|
|
|
Extracellular NAD+: a danger signal hindering regulatory T cells
Sahil Adriouch
,
Friedrich Haag
,
Olivier Boyer
,
Michel Seman
,
Friedrich Koch-Nolte
Article dans une revue
istex
hal-05224653
v1
|
|
|
Myoinjury transiently activates muscle antigen-specific CD8+ T cells in lymph nodes in a mouse model.
Hua Liao
,
Emilie Franck
,
Manuel Fréret
,
Sahil Adriouch
,
Yasmine Baba-Amer
et al.
Article dans une revue
inserm-00750113
v1
|
|
|
Alternative Splicing of the N-Terminal Cytosolic and Transmembrane Domains of P2X7 Controls Gating of the Ion Channel by ADP-Ribosylation
Nicole Schwarz
,
Laurent Drouot
,
Annette Nicke
,
Ralf Fliegert
,
Olivier Boyer
et al.
Article dans une revue
hal-05224657
v1
|
|
|
Immunological Tolerance to Muscle Autoantigens Involves Peripheral Deletion of Autoreactive CD8+ T Cells
Emilie Franck
,
Carole Bonneau
,
Laetitia Jean
,
Jean-Paul Henry
,
Yann Lacoume
et al.
Article dans une revue
hal-05224649
v1
|
|
|
Myoinjury transiently activates muscle antigen–specific CD8+ T cells in lymph nodes in a mouse model
Hua Liao
,
Emilie Franck
,
Manuel Fréret
,
Sahil Adriouch
,
Yasmine Baba-Amer
et al.
Article dans une revue
hal-05224656
v1
|
|
|
Improved Immunological Tolerance Following Combination Therapy with CTLA-4/Ig and AAV-Mediated PD-L1/2 Muscle Gene Transfer
Sahil Adriouch
,
Emilie Franck
,
Laurent Drouot
,
Carole Bonneau
,
Nelly Jolinon
et al.
Article dans une revue
hal-05224646
v1
|
|
|
Extracellular NAD+ shapes the Foxp3+ regulatory T cell compartment through the ART2–P2X7 pathway
Sandra Hubert
,
Björn Rissiek
,
Katjana Klages
,
Jochen Huehn
,
Tim Sparwasser
et al.
Article dans une revue
hal-05224572
v1
|
|
|
Activation of the P2X7 ion channel by soluble and covalently bound ligands
Nicole Schwarz
,
Ralf Fliegert
,
Sahil Adriouch
,
Michel Seman
,
Andreas Guse
et al.
Article dans une revue
hal-05224628
v1
|
|
|
ADP‐ribosylation of membrane proteins: Unveiling the secrets of a crucial regulatory mechanism in mammalian cells
Friedrich Koch-Nolte
,
Sahil Adriouch
,
Peter Bannas
,
Christian Krebs
,
Felix Scheuplein
et al.
Article dans une revue
hal-05224603
v1
|
|
|
Single domain antibodies: promising experimental and therapeutic tools in infection and immunity
Janusz Wesolowski
,
Vanina Alzogaray
,
Jan Reyelt
,
Mandy Unger
,
Karla Juarez
et al.
Article dans une revue
hal-05224566
v1
|
|
|
NAD+ and ATP Released from Injured Cells Induce P2X7-Dependent Shedding of CD62L and Externalization of Phosphatidylserine by Murine T Cells
Sahil Adriouch
,
Felix Scheuplein
,
Robert Bähring
,
Michel Seman
,
Olivier Boyer
et al.
Article dans une revue
hal-05224620
v1
|
|
|
Monitoring the expression of purinoceptors and nucleotide-metabolizing ecto-enzymes with antibodies directed against proteins in native conformation
Felix Scheuplein
,
Nicole Schwarz
,
Sahil Adriouch
,
Christian Krebs
,
Peter Bannas
et al.
Article dans une revue
hal-05224618
v1
|
|
|
Characterisation of the R276A gain-of-function mutation in the ectodomain of murine P2X7
Nicole Schwarz
,
Ralf Fliegert
,
Sahil Adriouch
,
Michel Seman
,
Andreas Guse
et al.
Article dans une revue
hal-05224621
v1
|
|
|
Cutting Edge: CD4-Independent Development of Functional FoxP3+ Regulatory T Cells
Céline Blache
,
Sahil Adriouch
,
Sébastien Calbo
,
Laurent Drouot
,
Sophie Dulauroy
et al.
Article dans une revue
hal-05224640
v1
|
|
|
ADP‐ribosylation at R125 gates the P2X7 ion channel by presenting a covalent ligand to its nucleotide binding site
Sahil Adriouch
,
Peter Bannas
,
Nicole Schwarz
,
Ralf Fliegert
,
Andreas Guse
et al.
Article dans une revue
hal-05224610
v1
|
|
|
Extracellular NAD and ATP: Partners in immune cell modulation
Friedrich Haag
,
Sahil Adriouch
,
Anette Braß
,
Caroline Jung
,
Sina Möller
et al.
Article dans une revue
hal-05224614
v1
|
|
|
NAD+ Released during Inflammation Participates in T Cell Homeostasis by Inducing ART2-Mediated Death of Naive T Cells In Vivo
Sahil Adriouch
,
Sandra Hubert
,
Severine Pechberty
,
Friedrich Koch-Nolte
,
Friedrich Haag
et al.
Article dans une revue
hal-05224606
v1
|
|
|
Probing the expression and function of the P2X7 purinoceptor with antibodies raised by genetic immunization
Sahil Adriouch
,
Gudrun Dubberke
,
Philip Diessenbacher
,
François Rassendren
,
Michel Seman
et al.
Article dans une revue
istex
hal-05224599
v1
|
|
|
Probing the expression and function of the P2X7 purinoceptor with antibodies raised by genetic immunization
S. Adriouch
,
G. Dubberke
,
P. Diessenbacher
,
François Rassendren
,
M. Seman
et al.
Article dans une revue
istex
hal-00016889
v1
|
|
|
CD38 Controls ADP-Ribosyltransferase-2-Catalyzed ADP-Ribosylation of T Cell Surface Proteins
Christian Krebs
,
Sahil Adriouch
,
Fenja Braasch
,
Wolfgang Koestner
,
Edward Leiter
et al.
Article dans une revue
hal-05224591
v1
|
|
|
Activity and specificity of toxin-related mouse T cell ecto–ADP-ribosyltransferase ART2.2 depends on its association with lipid rafts
Peter Bannas
,
Sahil Adriouch
,
Sarah Kahl
,
Fenja Braasch
,
Friedrich Haag
et al.
Article dans une revue
hal-05224590
v1
|
|
|
Ecto-ADP-Ribosyltransferases (ARTs): Emerging Actors in Cell Communication and Signaling
Michel Seman
,
Sahil Adriouch
,
Friedrich Haag
,
Friedrich Koch-Nolte
Article dans une revue
istex
hal-05224583
v1
|
|
|
NAD-Induced T Cell Death: ADP-Ribosylation of Cell Surface Proteins by ART2 Activates the Cytolytic P2X7 Purinoceptor
Michel Seman
,
Sahil Adriouch
,
Felix Scheuplein
,
Christian Krebs
,
Dunja Freese
et al.
Article dans une revue
hal-05224549
v1
|
|
|
Convergent alteration of granulopoiesis, chemotactic activity, and neutrophil apoptosis during mouse selection for high acute inflammatory response
Orlando Ribeiro
,
Durvanei Maria
,
Sahil Adriouch
,
Séverine Pechberty
,
Wafa Cabrera
et al.
Article dans une revue
hal-05224535
v1
|
|
|
T Cells of Different Developmental Stages Differ in Sensitivity to Apoptosis Induced by Extracellular NAD
Friedrich Haag
,
Dunja Freese
,
Felix Scheublein
,
Wiebke Ohlrogge
,
Sahil Adriouch
et al.
Article dans une revue
hal-05224588
v1
|
|
|
Cutting Edge: A Natural P451L Mutation in the Cytoplasmic Domain Impairs the Function of the Mouse P2X7 Receptor
Sahil Adriouch
,
Claudia Dox
,
Vivienne Welge
,
Michel Seman
,
Friedrich Koch-Nolte
et al.
Article dans une revue
hal-05224524
v1
|