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Said Assou




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The Transcriptome Landscape of the In Vitro Human Airway Epithelium Response to SARS-CoV-2

Said Assou , Engi Ahmed , Lisa Morichon , Amel Nasri , Florent Foisset
International Journal of Molecular Sciences, 2023, 24 (15), pp.12017. ⟨10.3390/ijms241512017⟩
Journal articles hal-04180636v1
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Production of innervated bronchial epithelium from a blood sample

Florent Foisset , Christine Lehalle , Amel Nasri , Carine Bourdais , Lisa Morichon
Revue des Maladies Respiratoires, 2023, 23, pp.S0761-8425. ⟨10.1016/j.rmr.2023.01.021⟩
Journal articles hal-03989840v1
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Using intracellular SCGB1A1-sorted, formalin-fixed club cells for successful transcriptomic analysis

Charlotte Vernisse , Aurélie Petit , Véronique Pantesco , Pascal Chanez , Delphine Gras
Biochemical and Biophysical Research Communications, 2022, 604, pp.151-157. ⟨10.1016/j.bbrc.2022.03.040⟩
Journal articles hal-03611547v1
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Differentiation of Human Induced Pluripotent Stem Cells from Patients with Severe COPD into Functional Airway Epithelium

Engi Ahmed , Mathieu Fieldes , Chloé Bourguignon , Joffrey Mianné , Aurélie Petit
Cells, 2022, 11 (15), pp.2422. ⟨10.3390/cells11152422⟩
Journal articles hal-03751524v1
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Platelets Purification Is a Crucial Step for Transcriptomic Analysis

Mohamad Chebbo , Said Assou , Veronique Pantesco , Catherine Duez , Marie Alessi
International Journal of Molecular Sciences, 2022, 23 (6), pp.3100. ⟨10.3390/ijms23063100⟩
Journal articles hal-03791989v1
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CRISPR/Cas9-mediated gene knockout and interallelic gene conversion in human induced pluripotent stem cells using non-integrative bacteriophage-chimeric retrovirus-like particles

Joffrey Mianné , Amel Nasri , Chloé Nguyen Van , Chloé Bourguignon , Mathieu Fieldès
BMC Biology, 2022, 20 (1), pp.8. ⟨10.1186/s12915-021-01214-x⟩
Journal articles hal-03518180v1
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Molecular Profiling of Spermatozoa Reveals Correlations between Morphology and Gene Expression: A Novel Biomarker Panel for Male Infertility

Nino Guy Cassuto , David Piquemal , Florence Boitrelle , Lionel Larue , Nathalie Lédée
BioMed Research International , 2021, 2021, pp.1 - 14. ⟨10.1155/2021/1434546⟩
Journal articles hal-03369698v1
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Identification of a Novel Serum Proteomic Signature for Primary Sjögren’s Syndrome

Guillaume Padern , Claire Duflos , Rosanna Ferreira , Said Assou , Philippe Guilpain
Frontiers in Immunology, 2021, 12, pp.631539. ⟨10.3389/fimmu.2021.631539⟩
Journal articles hal-03628071v1
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NRG1/ErbB signalling controls the dialogue between macrophages and neural crest-derived cells during zebrafish fin regeneration

Béryl Laplace-Builhé , Audrey Barthelaix , Said Assou , Candice Bohaud , Marine Pratlong
Nature Communications, 2021, 12 (1), pp.6336. ⟨10.1038/s41467-021-26422-5⟩
Journal articles hal-03646943v1
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Transcriptome-Wide Analysis Reveals a Role for Extracellular Matrix and Integrin Receptor Genes in Otic Neurosensory Differentiation from Human iPSCs

Lejo Johnson Chacko , Hanae Lahlou , Claudia Steinacher , Said Assou , Yassine Messat
International Journal of Molecular Sciences, 2021, 22 (19), pp.10849. ⟨10.3390/ijms221910849⟩
Journal articles hal-03409973v1
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Roles of Mesenchymal Cells in the Lung: From Lung Development to Chronic Obstructive Pulmonary Disease

Amel Nasri , Florent Foisset , Engi Ahmed , Zakaria Lahmar , Isabelle Vachier
Cells, 2021, 10 (12), pp.3467. ⟨10.3390/cells10123467⟩
Journal articles hal-03478861v1
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Neuromedin B promotes chondrocyte differentiation of mesenchymal stromal cells via calcineurin and calcium signaling

Marie Maumus , Guillaume Fonteneau , Maxime Ruiz , Said Assou , Hassan Boukhaddaoui
Cell & Bioscience, 2021, 11 (1), pp.183. ⟨10.1186/s13578-021-00695-1⟩
Journal articles hal-03640035v1
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Selective treatment pressure in colon cancer drives the molecular profile of resistant circulating tumor cell clones

Laure Cayrefourcq , Frédéric Thomas , Thibault Mazard , Eric Assenat , Said Assou
Molecular Cancer, 2021, 20 (1), pp.30. ⟨10.1186/s12943-021-01326-6⟩
Journal articles hal-04349811v1
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Generation of four severe early-onset chronic obstructive pulmonary disease (COPD) patient-derived induced pluripotent stem cell lines from peripheral blood mononuclear cells

Engi Ahmed , Mathieu Fieldes , Joffrey Mianné , Chloé Bourguignon , Amel Nasri
Stem Cell Research, 2021, 56, pp.102550. ⟨10.1016/j.scr.2021.102550⟩
Journal articles hal-03377712v1
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Targeted therapy in eosinophilic chronic obstructive pulmonary disease

Mathieu Fieldes , Chloé Bourguignon , Said Assou , Amel Nasri , Aurélie Fort
ERJ Open Research, 2021, 7 (2), pp.00437-2020. ⟨10.1183/23120541.00437-2020⟩
Journal articles hal-03200459v1
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miR-155 Contributes to the Immunoregulatory Function of Human Mesenchymal Stem Cells

Yves-Marie Pers , Claire Bony , Isabelle Duroux-Richard , Laurène Bernard , Marie Maumus
Frontiers in Immunology, 2021, 12, pp.624024. ⟨10.3389/fimmu.2021.624024⟩
Journal articles hal-03660057v1
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Recurrent Genetic Abnormalities in Human Pluripotent Stem Cells: Definition and Routine Detection in Culture Supernatant by Targeted Droplet Digital PCR

Said Assou , Nicolas Girault , Mathilde Plinet , Julien Bouckenheimer , Caroline Sansac
Stem Cell Reports, 2020, 14 (1), pp.1-8. ⟨10.1016/j.stemcr.2019.12.004⟩
Journal articles hal-03396129v1
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Generation of the induced pluripotent stem cell line UHOMi002-A from peripheral blood mononuclear cells of a healthy male donor

Mathieu Fieldes , Engi Ahmed , Chloé Bourguignon , Joffrey Mianné , Martin Mélanie
Stem Cell Research, 2020, pp.102037. ⟨10.1016/j.scr.2020.102037⟩
Journal articles hal-02965353v1
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Pipeline for the Generation and Characterization of Transgenic Human Pluripotent Stem Cells Using the CRISPR/Cas9 Technology

Joffrey Mianné , Chloé Bourguignon , Chloé Nguyen Van , Mathieu Fieldès , Amel Nasri
Cells, 2020, 9 (5), pp.1312. ⟨10.3390/cells9051312⟩
Journal articles hal-03594394v1
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Whole embryo culture, transcriptomics and RNA interference identify TBX1 and FGF11 as novel regulators of limb development in the mouse

Gautier Tejedor , Béryl Laplace-Builhé , Patricia Luz-Crawford , Said Assou , Audrey Barthelaix
Scientific Reports, 2020, 10 (1), pp.3597. ⟨10.1038/s41598-020-60217-w⟩
Journal articles inserm-02498306v1
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Modélisation de l’épithélium bronchique dans la bronchopneumopathie chronique obstructive par les cellules souches pluripotentes induites humaines

M. Fieldès , E. Ahmed , C. Bourguignon , J. Mianné , C. Vernisse
Revue des Maladies Respiratoires, 2020, 37 (3), pp.197-200. ⟨10.1016/j.rmr.2020.02.003⟩
Journal articles hal-02507653v1
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Les organoïdes pulmonaires

Chloé Bourguignon , Charlotte Vernisse , Joffrey Mianné , Mathieu Fieldes , Engi Ahmed
Médecine/Sciences, 2020, 36 (4), pp.382-388. ⟨10.1051/medsci/2020056⟩
Journal articles hal-02560622v1
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Increased expression of the HDAC 9 gene is associated with antiestrogen‐resistance of breast cancers

Aurélien Linares , Said Assou , Marion Lapierre , Erwan Thouennon , Celine Duraffourd
Molecular Oncology, 2019, 13 (7), pp.1534-1547. ⟨10.1002/1878-0261.12505⟩
Journal articles hal-02133612v1

Follicular fluid and supernatant from cultured cumulus-granulosa cells improve in vitro maturation in patients with polycystic ovarian syndrome

Aicha Madkour , Nouzha Bouamoud , Ismail Kaarouch , Noureddine Louanjli , Saadani Brahim
Fertility and Sterility, 2018, 110 (4), pp.710-719. ⟨10.1016/j.fertnstert.2018.04.038⟩
Journal articles hal-03164781v1
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Induced Pluripotent Stem Cells for Primary Ciliary Dyskinesia Modeling and Personalized Medicine

Joffrey Mianné , Engi Ahmed , Chloé Bourguignon , Mathieu Fieldes , Isabelle Vachier
American Journal of Respiratory Cell and Molecular Biology, 2018, 59 (6), pp.672-683. ⟨10.1165/rcmb.2018-0213TR⟩
Journal articles hal-01878063v1
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Differential long non-coding RNA expression profiles in human oocytes and cumulus cells

Julien Bouckenheimer , Patricia Fauque , Charles-Henri Lecellier , Céline Bruno , Thérèse Commes
Scientific Reports, 2018, 8 (1), ⟨10.1038/s41598-018-20727-0⟩
Journal articles hal-01840077v1
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Autologous cell lines from circulating colon cancer cells captured from sequential liquid biopsies as model to study therapy-driven tumor changes

Alexandra Soler , Laure Cayrefourcq , Thibault Mazard , Anna Babayan , Pierre-Jean Lamy
Scientific Reports, 2018, 8, pp.15931. ⟨10.1038/s41598-018-34365-z⟩
Journal articles hal-02292363v1
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PATL2 is a key actor of oocyte maturation whose invalidation causes infertility in women and mice

Marie Christou‐kent , Zine‐eddine Kherraf , Amir Amiri‐yekta , Emilie Le Blévec , Thomas Karaouzène
EMBO Molecular Medicine, 2018, 10 (5), pp.e8515. ⟨10.15252/emmm.201708515⟩
Journal articles hal-01877992v1
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Generation of the induced pluripotent stem cell line UHOMi001-A from a patient with mutations in CCDC40 gene causing Primary Ciliary Dyskinesia (PCD)

Engi Ahmed , Caroline Sansac , Mathieu Fieldes , Anne Bergougnoux , Chloé Bourguignon
Stem Cell Research, 2018, ⟨10.1016/j.scr.2018.09.019⟩
Journal articles hal-01886353v1
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Enriched Differentiation of Human Otic Sensory Progenitor Cells Derived From Induced Pluripotent Stem Cells

Hanae Lahlou , Emmanuel Nivet , Alejandra Lopez-Juarez , Arnaud Fontbonne , Said Assou
Frontiers in Molecular Neuroscience, 2018, 11, pp.11:452. ⟨10.3389/fnmol.2018.00452⟩
Journal articles hal-02395531v1

Concise Review: Assessing the Genome Integrity of Human Induced Pluripotent Stem Cells: What Quality Control Metrics?

Said Assou , Julien Bouckenheimer , John de Vos
STEM CELLS, 2018, 36 (6), pp.814-821. ⟨10.1002/stem.2797⟩
Journal articles hal-02340889v1
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Lung development, regeneration and plasticity: From disease physiopathology to drug design using induced pluripotent stem cells

Engi Ahmed , Caroline Sansac , Said Assou , Delphine Gras , Aurélie Petit
Pharmacology and Therapeutics, 2018, 183, pp.58--77. ⟨10.1016/j.pharmthera.2017.10.002⟩
Journal articles hal-01743899v1

Paternal age: Negative impact on sperm genome decays and IVF outcomes after 40 years

Ismail Kaarouch , Nouzha Bouamoud , Aicha Madkour , Noureddine Louanjli , Saadani Brahim
Molecular Reproduction and Development, 2018, 85 (3), pp.271-280. ⟨10.1002/mrd.22963⟩
Journal articles hal-03158098v1

Molecular Portrait of Metastasis-Competent Circulating Tumor Cells in Colon Cancer Reveals the Crucial Role of Genes Regulating Energy Metabolism and DNA Repair

Catherine Alix-Panabières , Laure Cayrefourcq , Thibault Mazard , Thierry Maudelonde , Eric Assenat
Clinical Chemistry, 2017, 63 (3), pp.700 - 713. ⟨10.1373/clinchem.2016.263582⟩
Journal articles hal-01793403v1

Induced pluripotent stem cells: An unlimited source of organs for transplantation

John de Vos , Said Assou
Clinics and Research in Hepatology and Gastroenterology, 2017, 41 (3), pp.249 - 253. ⟨10.1016/j.clinre.2016.10.008⟩
Journal articles hal-01794741v1

Human induced pluripotent stem cells: A disruptive innovation

John de Vos , J. Bouckenheimer , C. Sansac , J.-M. Lemaître , Said Assou
Current Research in Translational Medicine, 2016, 64 (2), pp.91 - 96. ⟨10.1016/j.retram.2016.04.001⟩
Journal articles hal-01840116v1

Long non-coding RNAs in human early embryonic development and their potential in ART

Julien Bouckenheimer , Said Assou , Sébastien Riquier , Cyrielle Hou , Nicolas Philippe
Human Reproduction Update, 2016, 23 (1), pp.19 - 40. ⟨10.1093/humupd/dmw035⟩
Journal articles hal-01819458v1

Les cellules souches pluripotentes induites : un nouveau paradigme pour l’étude des tissus humains

Caroline Sansac , Said Assou , Julien Bouckenheimer , Jean-Marc Lemaitre , John de Vos
Biologie Aujourd'hui, 2016, 210 (1), pp.1 - 8. ⟨10.1051/jbio/2016013⟩
Journal articles hal-01840113v1
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Histone deacetylase 9 regulates breast cancer cell proliferation and the response to histone deacetylase inhibitors

Marion Lapierre , Aurélien Linares , Mathieu Dalvai , Céline Duraffourd , Sandrine Bonnet
Oncotarget, 2016, 7 (15), pp.19693-708. ⟨10.18632/oncotarget.7564⟩
Journal articles hal-01873610v1

Cultured Cells from the Human Oocyte Cumulus Niche Are Efficient Feeders to Propagate Pluripotent Stem Cells

Said Assou , Emilie Pourret , Marie Péquignot , Valérie Rigau , Vasiliki Kalatzis
Stem Cells and Development, 2015, 24 (19), pp.2317-2327. ⟨10.1089/scd.2015.0043⟩
Journal articles hal-01977969v1
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Female Aging Alters Expression of Human Cumulus Cells Genes that Are Essential for Oocyte Quality

Tamadir Al-Edani , Said Assou , Alice Ferrieres , Sophie Bringer Deutsch , Anna Gala
BioMed Research International , 2014, 2014, pp.1-10. ⟨10.1155/2014/964614⟩
Journal articles hal-02106439v1
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Endometrial Receptivity Profile in Patients with Premature Progesterone Elevation on the Day of hCG Administration

Delphine Haouzi , Laurence Bissonnette , Anna Gala , Said Assou , Frida Entezami
BioMed Research International , 2014, 2014, pp.951937. ⟨10.1155/2014/951937⟩
Journal articles hal-03122694v1

Non-invasive pre-implantation genetic diagnosis of X-linked disorders

Said Assou , Ounissa Aït-Ahmed , Safia El Messaoudi , Alain R Thierry , Samir Hamamah
Medical Hypotheses, 2014, 83, pp.506--8. ⟨10.1016/j.mehy.2014.08.019⟩
Journal articles hal-02181365v1

MicroRNAs: new candidates for the regulation of the human cumulus–oocyte complex

Diego Sánchez-Martínez , Ewelina Krzywinska , Moeez G. Rathore , Anne Saumet , Amélie Cornillon
Human Reproduction, 2013, 28 (11), pp.3038-3049. ⟨10.1093/humrep/det321⟩
Journal articles hal-02106446v1
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Transcriptomic analysis of the developing and adult mouse cochlear sensory epithelia

Ibtihel Smeti , Said Assou , Etienne Savary , Saber Masmoudi , Azel Zine
PLoS ONE, 2012, 7 (8), pp.e42987. ⟨10.1371/journal.pone.0042987⟩
Journal articles inserm-00840290v1
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Differences in transcriptomic profiles of human cumulus cells isolated from oocytes at GV, MI and MII stages after in vivo and in vitro oocyte maturation.

Zamalou Gisèle Ouandaogo , Nelly Frydman , Laetitia Hesters , Said Assou , Delphine Haouzi
Human Reproduction, 2012, 27 (8), pp.2438-47. ⟨10.1093/humrep/des172⟩
Journal articles inserm-00726681v1
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Transcriptome Analysis during Human Trophectoderm Specification Suggests New Roles of Metabolic and Epigenetic Genes.

Said Assou , Imène Boumela , Delphine Haouzi , Cécile Monzo , Hervé Dechaud
PLoS ONE, 2012, 7 (6), pp.e39306. ⟨10.1371/journal.pone.0039306⟩
Journal articles inserm-00726672v1
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Dissecting the first transcriptional divergence during human embryonic development.

Qiang Bai , Said Assou , Delphine Haouzi , Jean-Marie Ramirez , Cécile Monzo
Stem Cell Reviews and Reports, 2012, 8 (1), pp.150-62. ⟨10.1007/s12015-011-9301-3⟩
Journal articles inserm-00664573v1
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[Other actors in the oocyte and follicular growth: The role of microRNAs in the cumulus-oocyte dialog].

S. Moussaddykine , Said Assou , Hervé Déchaud , Samir Hamamah
Gynécologie Obstétrique & Fertilité, 2012, 40 (3), pp.170-3. ⟨10.1016/j.gyobfe.2011.10.011⟩
Journal articles inserm-00664585v1
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Slow freezing and vitrification differentially modify the gene expression profile of human metaphase II oocytes.

Cécile Monzo , Delphine Haouzi , K. Roman , Said Assou , Hervé Dechaud
Human Reproduction, 2012, 27 (7), pp.2160-8. ⟨10.1093/humrep/des153⟩
Journal articles inserm-00726705v1

Involvement of BCL2 family members in the regulation of human oocyte and early embryo survival and death: gene expression and beyond

Imène Boumela , Said Assou , Abdel Aouacheria , Delphine Haouzi , Hervé Dechaud
Reproduction, 2011, 141 (5), pp.549-561
Journal articles ensl-00808957v1
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Dynamic changes in gene expression during human early embryo development: from fundamental aspects to clinical applications.

Said Assou , Imène Boumela , Delphine Haouzi , Tal Anahory , Hervé Dechaud
Human Reproduction Update, 2011, 17 (2), pp.272-90. ⟨10.1093/humupd/dmq036⟩
Journal articles inserm-00512388v1
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Expression Map of the Human Exome in CD34+ Cells and Blood Cells: Increased Alternative Splicing in Cell Motility and Immune Response Genes.

Sylvie Tondeur , Céline Pangault , Tanguy Le Carrour , Yoann Lannay , Rima Benmahdi
PLoS ONE, 2010, 5 (2), pp.e8990. ⟨10.1371/journal.pone.0008990⟩
Journal articles inserm-00453226v1
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Correlating global gene regulation to angiogenesis in the developing chick extra-embryonic vascular system.

Sophie Javerzat , Mélanie Franco , John Herbert , Natalia Platonova , Anne-Lise Peille
PLoS ONE, 2009, 4 (11), pp.e7856. ⟨10.1371/journal.pone.0007856⟩
Journal articles inserm-00446190v1
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The CDK4-pRB-E2F1 pathway controls insulin secretion.

Jean-Sébastien Annicotte , Emilie Blanchet , Carine Chavey , Irena Iankova , Safia Costes
Nature Cell Biology, 2009, 11 (8), pp.1017-23. ⟨10.1038/ncb1915⟩
Journal articles inserm-00418907v1
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A gene expression signature shared by human mature oocytes and embryonic stem cells.

Said Assou , Doris Cerecedo , Sylvie Tondeur , Véronique Pantesco , Outi Hovatta
BMC Genomics, 2009, 10, pp.10. ⟨10.1186/1471-2164-10-10⟩
Journal articles inserm-00369777v1
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Gene expression profile of human endometrial receptivity: comparison between natural and stimulated cycles for the same patients.

Delphine Haouzi , Said Assou , K. Mahmoud , Sylvie Tondeur , Thierry Rème
Human Reproduction, 2009, 24 (6), pp.1436-45. ⟨10.1093/humrep/dep039⟩
Journal articles inserm-00377444v1

[Biology and potential of human embryonic stem cells]

Sylvie Tondeur , Said Assou , Laure Nadal , Samir Hamamah , John de Vos
Annales de Biologie Clinique, 2008, 66 (3), pp.241-7. ⟨10.1684/abc.2008.0224⟩
Journal articles inserm-00358937v1

Total fertilization failure and molecular abnormalities in metaphase II oocytes.

Stéphan Gasca , Lionel Reyftmann , Franck Pellestor , Thierry Rème , Said Assou
Reproductive BioMedicine Online, 2008, 17 (6), pp.772-81. ⟨10.1016/s1472-6483(10)60404-x⟩
Journal articles inserm-00358936v1
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Identifying new human oocyte marker genes: a microarray approach.

Stéphan Gasca , Franck Pellestor , Said Assou , Vanessa Loup , Tal Anahory
Reproductive BioMedicine Online, 2007, 14 (2), pp.175-183. ⟨10.1016/s1472-6483(10)60785-7⟩
Journal articles inserm-00131300v1
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A meta-analysis of human embryonic stem cells transcriptome integrated into a web-based expression atlas.

Said Assou , Tanguy Lecarrour , Sylvie Tondeur , Susanne Strom , Audrey Gabelle
STEM CELLS, 2007, 25 (4), pp.961-73. ⟨10.1634/stemcells.2006-0352⟩
Journal articles inserm-00128925v1
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The human cumulus--oocyte complex gene-expression profile.

Said Assou , Tal Anahory , Véronique Pantesco , Tanguy Le Carrour , Franck Pellestor
Human Reproduction, 2006, 21 (7), pp.1705-19. ⟨10.1093/humrep/del065⟩
Journal articles inserm-00130809v1
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Cyclin D3 promotes adipogenesis through activation of peroxisome proliferator-activated receptor gamma.

David A. Sarruf , Irena Iankova , Anna Abella , Said Assou , Stéphanie Miard
Molecular and Cellular Biology, 2005, 25 (22), pp.9985-95. ⟨10.1128/MCB.25.22.9985-9995.2005⟩
Journal articles inserm-00144667v1