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Sebastien Benzekry
Head of the Inria – Inserm project team COMPO (COMPutational pharmacology and clinical Oncology)
86%
Open access
119
Documents
Current affiliations
- 1071285
Researcher identifiers
- sebastien-benzekry
- Arxiv : benzekry_s_1
- 0000-0002-3749-8637
- Google Scholar : https://scholar.google.fr/citations?user=xsLpdFAAAAAJ&hl=fr&oi=ao
- IdRef : 159344212
Presentation
Sebastien Benzekry is a scientific researcher (PhD, HDR) at Inria, the french institute for applied mathematics, computer science and their applications. He has created (in 2021) and heads the Inria – Inserm (French national institute for biomedical research) project-team COMPO (COMPutational pharmacology and clinical Oncology), affiliated to both Inria and the Center for Research on Cancer of Marseille (Inserm U1068, CNRS UMR7258, Institut Paoli-Calmettes Institute, Aix-Marseille University, Faculty of Pharmacy). The objective of his research is to model data arising from (clinical) oncology in order to 1) bring clinical decision tools to enhance therapeutic management, 2) better inform and design clinical trials and 3) test biological hypotheses. To do so, he combines mechanistic (i.e., simulation models of the pharmaco-patho-physiological processes in cancer) and statistical learning through an approach termed 'mechanistic learning'. He has fifteen years of experience in trans-disciplinary projects in oncology, with a strong track record of publications in high impact journals (Cancer Res, PLoS Comp Biol, Clin Pharmacol Ther,...). His main topics of research are modeling metastatic development and immuno-oncology, integrating longitudinal data. These are implemented into code libraries developed with a focus on software development standards.
Dr Benzekry has an initial training in applied mathematics (Ecole Normale Supérieure) followed by a PhD at Aix-Marseille University and further training in computational / systems biology as a postdoc in the Center for Cancer and Systems Biology, Tufts Univ, Boston, MA.
Citations: 2095, h-index 24 (11/2011 – 03/2024), 50 research articles, 24 book chapters, editorials and proceedings.
https://team.inria.fr/compo/
https://www-sop.inria.fr/members/Sebastien.Benzekry/index.html
https://scholar.google.fr/citations?user=xsLpdFAAAAAJ&hl=fr&oi=ao
Publications
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Population Modeling of Tumor Growth Curves, the Reduced Gompertz Model and Prediction of the Age of a TumorMathematical and Computational Oncology, pp.87-97, 2019, ⟨10.1007/978-3-030-35210-3_7⟩
Book sections
hal-02383995v1
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A Mathematical Model for Growing Metastases on Oncologists’s ServiceComputational Surgery and Dual Training, Springer, pp.331 - 338, 2014, ⟨10.1007/978-1-4614-8648-0_21⟩
Book sections
hal-01087708v1
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Mathematical modeling of tumor and metastatic growth when treated with sunitinib[Research Report] Inria Bordeaux Sud-Ouest. 2016
Reports
hal-01377994v1
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Around a mathematical model of the concomitant tumor resistance phenomenon[Research Report] INRIA Bordeaux; Equipe MONC; INSA Toulouse. 2016
Reports
hal-01420449v1
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Modeling, mathematical and numerical analysis of anti-cancerous therapies for metastatic cancersAnalysis of PDEs [math.AP]. Université Aix-Marseille 1 – Université de Provence, 2011. English. ⟨NNT : ⟩
Theses
tel-01658210v1
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Contributions in Mathematical Oncology: When Theory Meets RealityMathematics [math]. Université de Bordeaux, 2017
Habilitation à diriger des recherches
tel-01658070v1
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Quantitative modeling of metastasis: cancer at the organism scaleDoctoral. United States. 2021
Lectures
hal-03261886v1
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