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Sébastien Lefebvre

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  • 561027
  • 491276
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La nutrition est un enjeu physiologique et de l’accompagnement des animaux atteints d’affections chroniques. En qualité d’enseignant chercheur de nutrition clinique à VetAgro Sup (école vétérinaire de Lyon), je forme les futurs vétérinaires à mieux conseiller les propriétaires d’animaux concernant la nutrition. Dans ce but, j’ai développé des modules d’enseignement en nutrition clinique du chien et du chat ainsi qu’une méthode de choix rationnel des aliments par diagrammes. Enfin, en appuis de la profession vétérinaire, j’ai créé un logiciel d’analyse et de calcul de ration leur permettant d’analyser n’importe quel régime à destination du chien au du chat (du régime BARF au régime industriel, en passant par les rations ménagères). Je participe aussi à la vulgarisation des sciences par la création de vidéos :


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Comparative pharmacokinetics of difethialone stereoisomers in male and female rats and mice: development of an intra- and inter-species model to predict the suitable formulation mix

Antoine Rached , Virginie Lattard , Ambre Fafournoux , Hervé Caruel , Isabelle Fourel
Archives of Toxicology, 2022, 96 (2), pp.535-544. ⟨10.1007/s00204-021-03210-0⟩
Journal articles hal-03543058v2
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Asymptomatic Anticoagulant Rodenticide Exposure in Dogs and Cats—A French and Belgian Rural and Urban Areas Study

Tarek Mahjoub , Emilie Krafft , Léa Garnier , Amélie Mignard , Christophe Hugnet
Frontiers in Toxicology, 2022, 4, pp.907892. ⟨10.3389/ftox.2022.907892⟩
Journal articles hal-03665510v1
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Exposure of predatory and scavenging birds to anticoagulant rodenticides in France: Exploration of data from French surveillance programs

Meg-Anne Moriceau , Sébastien Lefebvre , Isabelle Fourel , Etienne Benoit , Florence Buronfosse
Science of the Total Environment, 2022, 810, pp.151291. ⟨10.1016/j.scitotenv.2021.151291⟩
Journal articles hal-03419591v1
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Interest of the Faecal and Plasma Matrix for Monitoring the Exposure of Wildlife or Domestic Animals to Anticoagulant Rodenticides

Antoine Rached , Tarek Mahjoub , Ambre Fafournoux , Brigitte Barbier , Isabelle Fourel
Environmental Toxicology and Pharmacology, 2022, 97, pp.104033. ⟨10.1016/j.etap.2022.104033⟩
Journal articles hal-03888283v1
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Seasonal diet-based resistance to anticoagulant rodenticides in the fossorial water vole (Arvicola amphibius)

Rami Abil Khalil , Brigitte Barbier , Ambre Fafournoux , Ali Barka Mahamat , Aurélie Marquez
Environmental Research, 2021, 200, ⟨10.1016/j.envres.2021.111422⟩
Journal articles hal-03257639v2
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Biomarkers Potency to Monitor Non-target Fauna Poisoning by Anticoagulant Rodenticides

Antoine Rached , Meg-Anne Moriceau , Xavier Serfaty , Sébastien Lefebvre , Virginie Lattard
Frontiers in Veterinary Science, 2020, 7, ⟨10.3389/fvets.2020.616276⟩
Journal articles hal-03087267v1
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Comparative biological properties of the four stereoisomers of difethialone, a second-generation anticoagulant rodenticide, in rats: development of a model allowing to choose the appropriate stereoisomeric ratio

Sébastien Lefebvre , Isabelle Fourel , Nolan Chatron , Hervé Caruel , Etienne Benoit
Archives of Toxicology, 2020, 94 (3), pp.795-801. ⟨10.1007/s00204-020-02662-0⟩
Journal articles hal-02476692v1
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Accidental chlorophacinone exposure of lactating ewes: Clinical follow-up and human health dietary implications

Meg-Anne Moriceau , Sébastien Lefebvre , Isabelle Fourel , Etienne Benoit , Barnett Rattner
Food and Chemical Toxicology, 2020, 143, pp.111518. ⟨10.1016/j.fct.2020.111518⟩
Journal articles hal-02896032v1
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Differences in teratogenicity of some vitamin K antagonist substances used as human therapeutic or rodenticide are due to major differences in their fate after an oral administration

Thomas Chetot , Marjorie Mouette-Bonnet , Shira Taufana , Isabelle Fourel , Sébastien Lefebvre
Toxicology Letters, 2020, 333, pp.71-79. ⟨10.1016/j.toxlet.2020.07.034⟩
Journal articles hal-02912635v1
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Variability of ferulenol and ferprenin concentration in French giant fennel (Ferula sp.) leaves

Gilbert Gault , Sébastien Lefebvre , Etienne Benoit , Virginie Lattard , Denis Grancher
Toxicon, 2019, 165, pp.47-55. ⟨10.1016/j.toxicon.2019.04.010⟩
Journal articles hal-02118402v1
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Establishment of the Variation of Vitamin K Status According to Vkorc1 Point Mutations Using Rat Models

Jean Valéry Debaux , Abdessalem Hammed , Brigitte Barbier , Thomas Chetot , Etienne Benoit
Nutrients, 2019, 11 (9), pp.2076. ⟨10.3390/nu11092076⟩
Journal articles hal-02281066v1
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Thrombin generation test: A reliable tool to evaluate the pharmacodynamics of vitamin K antagonist rodenticides in rats

Georges Jourdi , Sébastien Lefebvre , Bernard Le Bonniec , Emmanuel Curis , Pascale Gaussem
Pesticide Biochemistry and Physiology, 2018, 146, pp.19 - 24. ⟨10.1016/j.pestbp.2018.02.004⟩
Journal articles hal-01713957v1
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Monitoring of antivitamin K-dependent anticoagulation in rodents – Towards an evolution of the methodology to detect resistance in rodents

Sébastien Lefebvre , Claire Hascoët , Marlène Damin-Pernik , Benoit Rannou , Etienne Benoit
Pesticide Biochemistry and Physiology, 2017, 138, pp.29 - 36. ⟨10.1016/j.pestbp.2017.02.003⟩
Journal articles hal-01571098v1
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Management of Rodent Populations by Anticoagulant Rodenticides: Toward Third-Generation Anticoagulant Rodenticides

Marlène Damin-Pernik , Bernadette Espana , Sébastien Lefebvre , Isabelle Fourel , Hervé Caruel
Drug Metabolism and Disposition, 2017, 45 (2), pp.160-165. ⟨10.1124/dmd.116.073791⟩
Journal articles hal-01564909v1
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A Review of Enrofloxacin for Veterinary Use

Tessa Trouchon , Sébastien Lefebvre
Open Journal of Veterinary Medicine, 2016, 6 (2), pp.40-58. ⟨10.4236/ojvm.2016.62006⟩
Journal articles hal-01503397v1
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Origin of the gender differences of the natural resistance to antivitamin K anticoagulants in rats

Sébastien Lefebvre , Benoit Rannou , Stéphane Besse , Etienne Benoit , Virginie Lattard
Toxicology, 2016, 344, pp.34-41. ⟨10.1016/j.tox.2016.02.002⟩
Journal articles hal-01503380v1
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Comparative inhibitory effect of prenylated coumarins, ferulenol and ferprenin, contained in the 'poisonous chemotype' of Ferula communis on mammal liver microsomal VKORC1 activity.

Marie-Sophie Louvet , Gilbert Gault , Sébastien Lefebvre , Florence Popowycz , Manon Boulven
Phytochemistry, 2015, 118 (118), pp.124-130. ⟨10.1016/j.phytochem.2015.08.012⟩
Journal articles hal-01577246v1

Rodenticide bait trials: how to conciliate scientific relevance and 3R principles. Comparison between European and USA regulatory requirements

Sébastien Lefebvre
12th European Vertebrate pest Management Congress, Sep 2019, Clermont-Ferrand, France
Conference papers hal-02882015v1
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Reflexion and proposition of a tool for teaching small animal nutrition in veterinary courses

Laurent Alvès de Oliveira , Denis Grancher , Sébastien Lefebvre
23. Congress of the European society of Veterinary & Comparative Nutrition, Sep 2019, Turin, Italy
Conference papers hal-02306173v1

Deadly ergot poisoning in a Charolais herd in France

Laurent Alvès de Oliveira , Sébastien Lefebvre , Jérôme Chantreau , Denis Grancher
3rd Vietnam Animal and Veterinary Science (AVS) National Conference., Sep 2019, Ho Chi Minh City, Vietnam
Conference papers hal-02881993v1

Asphodel exposure of sheep in Algeria.

S Fettata , Gilbert Gault , Sébastien Lefebvre , Etienne Benoit , Virginie Lattard
Proceedings for the 10th International Symposium on Poisonous Plants (ISOPP), Sep 2018, St Georges, United States
Conference papers hal-02912971v1

First giant fennel (Ferula sp.) intoxication in continental France.

Gilbert Gault , Sébastien Lefebvre , Claire Hascoet , Etienne Benoit , Virginie Lattard
Proceedings for the 10th International Symposium on Poisonous Plants (ISOPP), Sep 2018, St Georges, United States
Conference papers hal-02912975v1

Ferulenol exposure of calves in Corsica (France).

Gilbert Gault , Sébastien Lefebvre , Isabelle Fourel , Etienne Benoit , Virginie Lattard
Proceedings for the 10th International Symposium on Poisonous Plants (ISOPP), Sep 2018, St Georges, United States
Conference papers hal-02912977v1


Etienne Mas , Sébastien Lefebvre , Denis Grancher
Federation of Asian Veterinary Association Congress 2016, Sep 2016, Ho Chi Min City, Vietnam
Conference papers hal-02912963v1
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Labelled analytical constituents of commercial dog foods according to the main point of sale. Are there any clues as to the origin of phosphorus?

E Thiercy , A Rached , L Alves de Oliveira , Sébastien Lefebvre
Eurpean society of veterinary and comparative nutrition, Sep 2020, Vila Real (Online), Portugal
Conference poster hal-02920542v1
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You said "gastro-intestinal" food ? Approach of petfood diversity during a student-conducted consultation. Introduction

Sébastien Lefebvre , Denis Grancher , L Alves de Oliveira
23rd congress of the European Society of Veterinary and Comparative Nutrition (ESVCN 2019), Sep 2019, Turin, Italy.
Conference poster hal-02295150v1

Establishment of early endpoints for regulatory testing of anticoagulant rodenticides

Sébastien Lefebvre , Etienne Benoit , Virginie Lattard
12th European vertebrate pest management, Sep 2019, Clermont Ferrand, France
Conference poster hal-02882009v1
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Exposure of unweaned calves to the toxic compound of giant fennel

Gilbert Gault , Isabelle Fourel , Sébastien Lefebvre , Virginie Lattard , Denis Grancher
Congress of the European Society of Veterinary and Comparative Nutrition (ESVCN), 2017, Sep 2017, Cirencester, United Kingdom. Congress of the European Society of Veterinary and Comparative Nutrition (ESVCN), Cirencester (England), 2017, 2017
Conference poster hal-01590514v1
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Preliminary study on the efficiency of vitamin K on hypocoagulable rats. Introduction

Sébastien Lefebvre , Benoit Rannou , Stéphane Besse , Marlène Damin-Pernik , Etienne Benoit
Conference poster hal-01504509v1