Silvia Arcucci

21
Documents

Publications

Publications

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Mechanical compressive forces increase PI3K output signaling in breast and pancreatic cancer cells

Mickaël Di-Luoffo , Céline Schmitter , Emma C Barrere , Nicole Therville , Maria Chaouki et al.
Life Science Alliance, 2025, 8 (3), pp.e202402854. ⟨10.26508/lsa.202402854⟩
Article dans une revue hal-04874687 v1
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Atomic force microscopy-single-molecule force spectroscopy unveils GPCR cell surface architecture

Etienne Dague , Véronique Pons , Alexandre Roland , Jean-Marc Azaïs , Silvia Arcucci et al.
Communications Biology, 2022, 5 (1), ⟨10.1038/s42003-022-03162-w⟩
Article dans une revue hal-03619367 v1

Organismal roles for the PI3Kα and β isoforms: their specificity, redundancy or cooperation is context-dependent

Silvia Arcucci , Fernanda Ramos-Delgado , Coralie Cayron , Nicole Therville , Marie-Pierre Gratacap et al.
Biochemical Journal, 2021, 478 (6), pp.1199-1225. ⟨10.1042/BCJ20210004⟩
Article dans une revue hal-04819857 v1

Pancreatic cancer intrinsic PI3Kα activity accelerates metastasis and rewires macrophage component

Benoit Thibault , Fernanda Ramos-Delgado , Elvire Pons-Tostivint , Nicole Therville , Celia Cintas et al.
EMBO Molecular Medicine, 2021, 13 (7), ⟨10.15252/emmm.202013502⟩
Article dans une revue hal-05208185 v1
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Pancreatic cancer intrinsic PI3Kα activity accelerates metastasis and rewires macrophage component

Benoit Thibault , Fernanda Ramos‐delgado , Elvire Pons‐tostivint , Nicole Therville , Celia Cintas et al.
EMBO Molecular Medicine, 2021, 13 (7), pp.e13502. ⟨10.15252/emmm.202013502⟩
Article dans une revue hal-03625379 v1
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Mechanical Control of Cell Proliferation Increases Resistance to Chemotherapeutic Agents

Ilaria Francesca Rizzuti , Pietro Mascheroni , Silvia Arcucci , Zacchari Ben-Mériem , Audrey Prunet et al.
Physical Review Letters, 2020, 125 (12), pp.128103. ⟨10.1103/PhysRevLett.125.128103⟩
Article dans une revue hal-02943906 v1

Targeting the Sphingosine 1-Phosphate Axis Exerts Potent Antitumor Activity in BRAFi-Resistant Melanomas

David Garandeau , Justine Noujarède , Justine Leclerc , Caroline Imbert , Virginie Garcia et al.
Molecular Cancer Therapeutics, 2019, 18 (2), pp.289-300. ⟨10.1158/1535-7163.MCT-17-1141⟩
Article dans une revue hal-03194448 v1
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Experimental pancreatic cancer develops in soft pancreas: novel leads for an individualized diagnosis by ultrafast elasticity imaging

Nicole Therville , Silvia Arcucci , Aurélie Vertut , Fernanda Ramos-Delgado , Dina Ferreira da Mota et al.
Theranostics, 2019, 9, ⟨10.7150/thno.34066⟩
Article dans une revue hal-02500120 v1
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Signal-Targeted Therapies and Resistance Mechanisms in Pancreatic Cancer: Future Developments Reside in Proteomics

Celia Cintas , Thibaut Douche , Nicole Therville , Silvia Arcucci , Fernanda Ramos-Delgado et al.
Cancers, 2018, 10 (6), pp.174. ⟨10.3390/cancers10060174⟩
Article dans une revue hal-02500132 v1

PI3K signaling controls metabolic adaptations in pancreatic cancer

Coralie Cayron , Benoît Thibault , Silvia Arcucci , Mickael Di-Luoffo , Nicole Therville et al.
46th Symposium on hormones and cell regulation - Cancer signalling and metabolism, Oct 2024, Mont Sainte Odile, France
Communication dans un congrès hal-04922360 v1

Imaging the 3D cellular effects of compression in oncology: Application in pancreatic cancer

Romina D’Angelo , Silvia Arcucci , Nicole Therville , Celine Denais , Morgan Delarue et al.
Atelier pour le 1st meeting of the France-BioImaging Mechanobiology WG, Mechanobiology Working Group FBI, Dec 2024, Toulouse, France
Communication dans un congrès hal-04908796 v1

Mechanical stress & signal integration by PI3Ks for the control of tumour growth.

Sanzhar Aitbay , Hala Shalhoub , Romina D’Angelo , Nicole Therville , Silvia Arcucci et al.
4th PIPgen annual meeting, PIPgen, Sep 2024, Cambridge, United Kingdom
Communication dans un congrès hal-04924047 v1

Impact of mechanical compressive stress on pancreatic cancer progression

Mickael Di-Luoffo , Nicole Therville , Silvia Arcucci , Romina D’Angelo , Benoît Thibault et al.
Mechanobiology Club of Toulouse, Jan 2023, Toulouse, France
Communication dans un congrès hal-04908762 v1

L’enzyme de synthèse de la sérine PHGDH et la phosphatidyl-inositol kinase PI3Kα favorisent le potentiel de régénération du pancréas sous stress nutritif

Coralie Cayron , Dimitra Bozoglou , Amélie Villard , Gabriela Reyes-Castellanos , Nicole Therville et al.
Congrès annuel du CECED, Mar 2023, Strasbourg, France
Communication dans un congrès hal-04922375 v1

Imaging the 3D cellular effects of confinement in oncology: Application in pancreatic cancer

Romina D’Angelo , Silvia Arcucci , Laetitia Ligat , Nicole Therville , Celine Denais et al.
Signaling, Microenvironment and Targeting - GSO Workshop, Feb 2024, Toulouse, France. 2024
Poster de conférence hal-04917240 v1

PI3K signaling controls metabolic adaptations in pancreatic cancer

Coralie Cayron , Benoît Thibault , Silvia Arcucci , Mickael Di-Luoffo , Nicole Therville et al.
46th Symposium on Hormones and cell regulation - Cancer signalling and metabolism, Oct 2024, Mont Sainte Odile, France
Poster de conférence hal-04922358 v1

PI3Kβ controls mechanical parameters of pancreatic tumours predictive of poor survival.

Sanzhar Aitbay , Nicole Therville , Silvia Arcucci , Pauline Lefebvre , Mickael Di-Luoffo et al.
EMBO | EMBL Symposium Mechanobiology in development and disease, May 2022, Heidelberg, Germany. 2022
Poster de conférence hal-04923995 v1

PI3Kα signaling controls the balance between tissue regeneration and precancer lesion formation via PHGDH expression in pancreatic inflammation.

Coralie Cayron , Amélie Villard , Nicole Therville , Silvia Arcucci , Romain Baer et al.
Toulouse Onco Week 2020, Feb 2020, Toulouse, France
Poster de conférence hal-04922320 v1

Role of the class IA PI3K p110β subunit in pancreatic cancer.

Silvia Arcucci , Nicole Therville , Céline Basset , Aurélie Vertut , Julie Guillermet-Guibert
AACR PI3K, Nov 2019, Boston, United States. Molecular Cancer Research, 18 (10), pp.32-33, 2020
Proceedings/Recueil des communications hal-05028957 v1