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Sophie Sacquin-Mora

CNRS Research director
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  • 489
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It Takes Tau to Tango: Investigating the Fuzzy Interaction between the R2-Repeat Domain and Tubulin C-Terminal Tails

Jules Marien , Chantal Prévost , Sophie Sacquin-Mora
Biochemistry, 2023, 62 (16), pp.2492-2502. ⟨10.1101/2023.02.09.527845⟩
Journal articles hal-04177051v1
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Best Practices of Using AI-Based Models in Crystallography and Their Impact in Structural Biology

Marc Graille , Sophie Sacquin-Mora , Antoine Taly
Journal of Chemical Information and Modeling, inPress, ⟨10.1021/acs.jcim.3c00381⟩
Journal articles hal-04130165v1
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Conformational and mechanical stability of the isolated large subunit of membrane-bound [NiFe]-hydrogenase from Cupriavidus necator

Jovan Dragelj , Chara Karafoulidi-Retsou , Sagie Katz , Oliver Lenz , Ingo Zebger
Frontiers in Microbiology, 2023, 13, ⟨10.3389/fmicb.2022.1073315⟩
Journal articles hal-03965156v1
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Editorial: In Celebration of Women in Science: Biological Modeling and Simulation

Burcu Aykac Fas , Sophie Sacquin-Mora , Elena Papaleo
Frontiers in Molecular Biosciences, 2023, 10, ⟨10.3389/fmolb.2023.1175325⟩
Journal articles hal-04128274v1
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Between two walls: Modeling the adsorption behavior of β-glucosidase A on bare and SAM-functionalised gold surfaces

Nicolas Bourassin , Florent Barbault , Marc Baaden , Sophie Sacquin-Mora
Langmuir, 2022, 38 (4), pp.1313-1323. ⟨10.1021/acs.langmuir.1c01774⟩
Journal articles hal-03294641v1
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Modeling the Dynamics of Protein–Protein Interfaces, How and Why?

Ezgi Karaca , Chantal Prevost , Sophie Sacquin-Mora
Molecules, 2022, 27 (6), pp.1841. ⟨10.3390/molecules27061841⟩
Journal articles hal-03643994v1
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Design – a new way to look at old molecules

Davide Spalvieri , Anne-Marine Mauviel , Matthieu Lambert , Nicolas Férey , Sophie Sacquin-Mora
Journal of Integrative Bioinformatics, 2022, 19 (2), pp.20220020. ⟨10.1515/jib-2022-0020⟩
Journal articles hal-03793308v1
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When Order Meets Disorder: Modeling and Function of the Protein Interface in Fuzzy Complexes

Sophie Sacquin-Mora , Chantal Prevost
Biomolecules, 2021, 11 (10), pp.1529. ⟨10.3390/biom11101529⟩
Journal articles hal-03389754v1
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Moving pictures: Reassessing docking experiments with a dynamic view of protein interfaces

Chantal Prevost , Sophie Sacquin-Mora
Proteins - Structure, Function and Bioinformatics, 2021, 89 (10), pp.1315-1323. ⟨10.1002/prot.26152⟩
Journal articles hal-03065754v1
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Implicit Modeling of the Impact of Adsorption on Solid Surfaces for Protein Mechanics and Activity with a Coarse-Grain Representation

Nicolas Bourassin , Marc Baaden , Elisabeth Lojou , Sophie Sacquin-Mora
Journal of Physical Chemistry B, 2020, 15, ⟨10.1021/acs.jpcb.0c05347⟩
Journal articles hal-02939019v1
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Protein interaction energy landscapes are shaped by functional and also non-functional partners

Hugo Schweke , Marie-Hélène Mucchielli , Sophie Sacquin-Mora , Wanying Bei , Anne Lopes
Journal of Molecular Biology, 2020, 432 (4), pp.1183. ⟨10.1016/j.jmb.2019.12.047⟩
Journal articles hal-02445555v1
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Coarse-grain simulations on NMR conformational ensembles highlight functional residues in proteins

Sophie Sacquin-Mora
Journal of the Royal Society Interface, 2019, 16 (156), pp.20190075. ⟨10.1098/rsif.2019.0075⟩
Journal articles hal-02307948v1
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Conformational Stability Adaptation of a Double-Stranded RNA-Binding Domain to Transfer RNA Ligand

Charles Bou-Nader , Ludovic Pecqueur , Pierre Barraud , Marc Fontecave , Carine Tisné
Biochemistry, 2019, 58 (20), pp.2463-2473. ⟨10.1021/acs.biochem.9b00111⟩
Journal articles hal-04238753v1

Hidden partners: Using cross-docking calculations to predict binding sites for proteins with multiple interactions

Nathalie Lagarde , Alessandra Carbone , Sophie Sacquin-Mora
Proteins - Structure, Function and Bioinformatics, 2018, 86 (7), pp.723-737. ⟨10.1002/prot.25506⟩
Journal articles hal-02104315v1

Mechanical variations in proteins with large-scale motions highlight the formation of structural locks

Sophie Sacquin-Mora
Journal of Structural Biology, 2018, 203 (3), pp.195-204. ⟨10.1016/j.jsb.2018.05.006⟩
Journal articles hal-02104314v1
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Controlling Redox Enzyme Orientation at Planar Electrodes

Vivek Pratap Hitaishi , Romain Clément , Nicolas Bourassin , Marc Baaden , Anne de Poulpiquet
Catalysts, 2018, 8 (5), pp.192. ⟨10.3390/catal8050192⟩
Journal articles hal-01793660v1
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Meet-U: educating through research immersion

Nika Abdollahi , Alexandre Albani , Eric Anthony , Agnes Baud , Mélissa Cardon
PLoS Computational Biology, 2018, 14 (3), pp.1-10. ⟨10.1371/journal.pcbi.1005992⟩
Journal articles hal-01722019v1

Determinants of neuroglobin plasticity highlighted by joint coarse-grained simulations and high pressure crystallography.

Nathalie Colloc’h , Sophie Sacquin-Mora , Giovanna Avella , Anne-Claire Dhaussy , Thierry Prangé
Scientific Reports, 2017, 7 (1), pp.1858. ⟨10.1038/s41598-017-02097-1⟩
Journal articles hal-01523850v1

Mobility and core-protein binding patterns of disordered C-terminal tails in β-tubulin isotypes.

Yoann Laurin , Joël Eyer , Charles H. Robert , C Prévost , S. Sacquin-Mora
Biochemistry (mosc.), 2017, ⟨10.1021/acs.biochem.6b00988⟩
Journal articles hal-01497972v1

Bridging Enzymatic Structure Function via Mechanics: A Coarse-Grain Approach

Sophie Sacquin-Mora
Methods in Enzymology, 2016, ⟨10.1016/bs.mie.2016.05.022⟩
Journal articles hal-01451158v1
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Great interactions: How binding incorrect partners can teach us about protein recognition and function

Lydie Vamparys , Benoist Laurent , Alessandra Carbone , Sophie Sacquin-Mora
Proteins - Structure, Function and Bioinformatics, 2016, 84 (10), pp.1408-1421 ⟨10.1002/prot.25086⟩
Journal articles hal-01347160v1

Investigating the Structural Variability and Binding Modes of the Glioma Targeting NFL-TBS.40-63 Peptide on Tubulin

Yoann Laurin , Philippe Savarin , Charles H Robert , Masayuki Takahashi , Joël Eyer
Journal articles hal-01451181v1

Fold and flexibility: what can proteins' mechanical properties tell us about their folding nucleus?

Sophie Sacquin-Mora
Journal of the Royal Society Interface, 2015, ⟨10.1098/rsif.2015.0876⟩
Journal articles hal-01451165v1

How binding incorrect partners can lead to the prediction of correct interfaces: Results from a massive cross-docking study on proteins

Sophie Sacquin-Mora , Lydie Vamparys , Alessandra Carbone
Protein Science, 2015, 24 (1, SI), pp.243-244
Journal articles hal-01528524v1

Docking Peptides on Proteins: How to Open a Lock, in the Dark, with a Flexible Key

Sophie Sacquin-Mora , Chantal Prévost
Journal articles hal-01451174v1

Assessing the effect of dynamics on the closed-loop protein-folding hypothesis

Sree V. Chintapalli , Christopher J. R. Illingworth , Graham J. G. Upton , Sophie Sacquin-Mora , Philip J. Reeves
Journal of the Royal Society Interface, 2014, 11 (91), pp.20130935. ⟨10.1098/rsif.2013.0935⟩
Journal articles hal-01498046v1

Motions and mechanics: investigating conformational transitions in multi-domain proteins with coarse-grain simulations

Sophie Sacquin-Mora
Mol. Simul., 2014, 40 (1-3), pp.229--236. ⟨10.1080/08927022.2013.843176⟩
Journal articles hal-01498044v1

Multiscale Simulations Give Insight into the Hydrogen in- and out-Pathways of [NiFe]-Hydrogenases from Aquifex Aeolicus and Desulfovibrio Fructosovorans.

Francesco Oteri , Marc Baaden , Elisabeth Lojou , Sophie Sacquin-Mora
Journal of Physical Chemistry B, 2014, 118 (48), pp.13800-13811. ⟨10.1021/jp5089965⟩
Journal articles hal-01084622v1

The weak, fluctuating, dipole moment of membrane-bound hydrogenase from Aquifex aeolicus accounts for its adaptability to charged electrodes

Francesco Oteri , Alexandre Ciaccafava , Anne De Poulpiquet , Marc Baaden , Elisabeth. Lojou
Physical Chemistry Chemical Physics, 2014, 16 (23), pp.11318-11322. ⟨10.1039/C4CP00510D⟩
Journal articles hal-01493492v1

Heme orientation modulates histidine dissociation and ligand binding kinetics in the hexacoordinated human neuroglobin.

Anthony Bocahut , Valérie Derrien , Sophie Bernad , Pierre Sebban , Sophie Sacquin-Mora
Journal of Biological Inorganic Chemistry, 2013, 18 (1), pp.111-22. ⟨10.1007/s00775-012-0956-2⟩
Journal articles hal-00783539v1

Protein-protein interactions in a crowded environment: an analysis via cross-docking simulations and evolutionary information

Anne Lopes , Sophie Sacquin-Mora , Viktoriya Dimitrova , Elodie Laine , Yann Ponty
PLoS Computational Biology, 2013, 9 (12), pp.e1003369. ⟨10.1371/journal.pcbi.1003369⟩
Journal articles hal-00875116v1

Heme orientation modulates histidine dissociation and ligand binding kinetics in the hexacoordinated human neuroglobin

A Bocahut , V Derrien , S Bernad , P. Sebban , S Sacquin-Mora
Journal of Biological Inorganic Chemistry, 2013, 18 (1)
Journal articles hal-01326196v1

Thermal fluctuations of haemoglobin from different species: adaptation to temperature via conformational dynamics

A. M. Stadler , C. J. Garvey , A. Bocahut , S. Sacquin-Mora , I. Digel
Journal of the Royal Society Interface, 2012, 9 (76), pp.2845--2855. ⟨10.1098/rsif.2012.0364⟩
Journal articles hal-01498101v1

Enzyme closure and nucleotide binding structurally lock guanylate kinase.

Olivier Delalande , Sophie Sacquin-Mora , Marc Baaden
Biophysical Journal, 2011, 101 (6), pp.1440-9. ⟨10.1016/j.bpj.2011.07.048⟩
Journal articles hal-00645163v1

Functional Modes and Residue Flexibility Control the Anisotropic Response of Guanylate Kinase to Mechanical Stress

Sophie Sacquin-Mora , Olivier Delalande , Marc Baaden
Biophysical Journal, 2010, 99 (10), pp.3412-3419. ⟨10.1016/j.bpj.2010.09.026⟩
Journal articles hal-00602505v1
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Joint evolutionary trees: a large-scale method to predict protein interfaces based on sequence sampling.

Stefan Engelen , Ladislas A. Trojan , Sophie Sacquin-Mora , Richard Lavery , Alessandra Carbone
PLoS Computational Biology, 2009, 5 (1), pp.e1000267. ⟨10.1371/journal.pcbi.1000267⟩
Journal articles inserm-00705756v1

Probing macromolecular mechanics: Heterogeneity and function

(lavery Laveryr , (sacquin-Mora Sacquin-Moras , Xxxx Sophie)
Journal articles hal-00315127v1

Protein mechanics: a route from structure to function.

R. Lavery , S. Sacquin-Mora
Journal of Biosciences, 2007, 32, pp.891-898
Journal articles hal-00315141v1

Investigating the local flexibility of functional residues in hemoproteins.

S. Sacquin-Mora , R. Lavery
Biophysical Journal, 2006, 90, pp.2706-2717
Journal articles hal-00313391v1

Modelling redox enzymes on solid surfaces : Lessons from multiscale approaches

Sophie Sacquin-Mora
Atelier thématique, Bioélectrochimie aux Frontières, Mar 2023, Marseille-Online, France
Conference papers hal-04028399v1

From QM to coarse-grain, lessons from multiscale-modelling of redox enzymes

Sophie Sacquin-Mora
XVIIth GFB (Groupe Français de Bioélectrochimie ) Conference, Sep 2022, Saint Dié-des-Vosges, France
Conference papers hal-03790569v1

Multiscale modeling approaches for the protein-solid interface

Sophie Sacquin-Mora
Journées Plénières du GDR EMIE, Jun 2022, Dunkerque, France
Conference papers hal-03701647v1

Moving pictures: Reassessing docking experiments with a dynamic view of protein interfaces

Sophie Sacquin-Mora , Chantal Prévost
The ISQBP President’s Meeting 2021, Jun 2021, Strasbourg, France
Conference papers hal-04061587v1

Determinants of neuroglobin plasticity highlighted by high pressure crystallography and crystallography under moderate gas pressure

N Colloc'H , E Girard , T Prangé , P Carpentier , S Sacquin-Mora
56th european high pressure research group meeting, Sep 2018, Aveiro, Portugal
Conference papers hal-02267162v1

Determinants of neuroglobin plasticity highlighted by high pressure crystallography and crystallography under moderate gas pressure

N Colloc'H , E Girard , T Prangé , P Carpentier , S Sacquin-Mora
13th SOLEIL user's meeting, Jan 2018, Palaiseau, France
Conference papers hal-02267167v1

Fluides nanoconfinés dans des systèmes de basse symétrie : Simulations et théorie

Sophie Sacquin-Mora
Analyse de données, Statistiques et Probabilités []. Université Paris Sud - Paris XI, 2003. Français. ⟨NNT : ⟩
Theses tel-00008790v1
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Représentations gros-grain pour la modélisation des protéines : Propriétés mécaniques et interactions

Sacquin-Mora Sophie
Chimie théorique et/ou physique. Université Paris-Diderot - Paris VII, 2011
Habilitation à diriger des recherches tel-00652917v1