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Stephane Guindon

42
Documents
Current affiliations
  • 1100627
Researcher identifiers
  • IdHAL stephane-guindon
  • Google Scholar : https://scholar.google.co.nz/citations?hl=en&user=kvrvJccAAAAJ&view_op=list_works
  • IdRef : 078807824
  • ORCID 0000-0002-3665-8096

Presentation

I design probabilistic models of evolution and algorithms to infer their parameters from the analysis of molecular, fossil and/or spatial data. I created and am still developping the software package \[PhyML\](https://github.com/stephaneguindon/phyml) (for Phylogenetics through Maximum Likelihood) which serves as a basis to implement my research outputs. Trained as a biologist/statistician, I am working as a CNRS research scientist in the computer science department of the \[LIRMM\](https://www.lirmm.fr/equipes/MAB/) in Montpellier, France. I was also lucky to work for the \[Department of Statistics\](https://www.auckland.ac.nz/en/science/about-the-faculty/department-of-statistics.html) at the University of Auckland between 2007 and 2015. #### Miscellaneous Associate editor for Systematic Biology and BMC Evolutionary Biology. Scientific head of the ATGC platform. Co-chair and organizer of the annual conference "Mathematical and Computational Evolution". Served as member of the council for the Society of Systematic Biologists (until 2016). PI on ANR grant GENOSPACE (2016-2021) and Royal Society of New Zealand Marsden grant (2008-2011)

Research domains

Bioinformatics [q-bio.QM]

Publications

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EvoLaps 2 : Advanced phylogeographic visualization

François Chevenet , Denis Fargette , Paul Bastide , Thomas Vitré , Stéphane Guindon
Virus Evolution, 2024, 10 (1), pp.1-9. ⟨10.1093/ve/vead078⟩
Journal articles hal-04531387v1
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Rate of coalescence of lineage pairs in the Spatial Λ -Fleming–Viot process

Johannes Wirtz , Stéphane Guindon
Theoretical Population Biology, 2022, 146, pp.15-28. ⟨10.1016/j.tpb.2022.05.002⟩
Journal articles lirmm-03875375v1
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Éclairer les origines de la COVID-19 à partir de l’analyse comparée des génomes viraux

Stéphane Guindon , Celine Scornavacca
Interstices, 2022
Journal articles hal-03872208v1
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Sampling bias and model choice in continuous phylogeography: getting lost on a random walk

Antanas Kalkauskas , Umberto Perron , Yuxuan Sun , Nick Goldman , Guy Baele
PLoS Computational Biology, 2021, 17 (1), pp.e1008561. ⟨10.1371/journal.pcbi.1008561⟩
Journal articles hal-03064800v2
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Rivers and landscape ecology of a plant virus, Rice yellow mottle virus along the Niger Valley

Souley Issaka , Oumar Issiaka I. Traore , Régis Dimitri Skopé Longué , Agnès Pinel-Galzi , Mandev S. Gill
Virus Evolution, 2021, 7 (2), pp.veab072. ⟨10.1093/ve/veab072⟩
Journal articles hal-03365735v1
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Accounting for spatial sampling patterns in Bayesian phylogeography

Stéphane Guindon , Nicola de Maio
Proceedings of the National Academy of Sciences of the United States of America, 2021, 118 (52), pp.e2105273118. ⟨10.1073/pnas.2105273118⟩
Journal articles lirmm-03875373v1
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EvoLaps: a web interface to visualize continuous phylogeographic reconstructions

François Chevenet , Denis Fargette , Stéphane Guindon , Anne-Laure Bañuls
BMC Bioinformatics, 2021, 22 (1), pp.#463. ⟨10.1186/s12859-021-04386-z⟩
Journal articles hal-03378825v1
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Rates and Rocks: Strengths and Weaknesses of Molecular Dating Methods

Stéphane Guindon
Frontiers in Genetics, 2020, 11, pp.#526. ⟨10.3389/fgene.2020.00526⟩
Journal articles lirmm-03064771v1
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Accounting for ambiguity in ancestral sequence reconstruction

Adrien Oliva , Sylvain Pulicani , Vincent Lefort , Laurent Brehelin , Olivier Gascuel
Bioinformatics, 2019, 35 (21), pp.4290-4297. ⟨10.1093/bioinformatics/btz249⟩
Journal articles pasteur-02404399v1
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Accounting for Calibration Uncertainty: Bayesian Molecular Dating as a “Doubly Intractable” Problem

Stéphane Guindon
Systematic Biology, 2018, 67 (4), pp.651-661. ⟨10.1093/sysbio/syy003⟩
Journal articles lirmm-01800299v1
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HIV-1 Full-Genome Phylogenetics of Generalized Epidemics in Sub-Saharan Africa: Impact of Missing Nucleotide Characters in Next-Generation Sequences

Oliver Ratmann , Chris Wymant , Caroline Colijn , Siva Danaviah , Max Essex
AIDS Research and Human Retroviruses, 2017, 33 (11), pp.1083-1098. ⟨10.1089/aid.2017.0061⟩
Journal articles lirmm-01800302v1

Demographic inference under the coalescent in a spatial continuum

Stéphane Guindon , Hongbin Guo , David Welch
Theoretical Population Biology, 2016, 111, pp.43-50. ⟨10.1016/j.tpb.2016.05.002⟩
Journal articles lirmm-01347481v1
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Molecular Evolution of the TET Gene Family in Mammals

Hiromichi Akahori , Stéphane Guindon , Sumio Yoshizaki , Yoshinori Muto
International Journal of Molecular Sciences, 2015, 16 (12), pp.28472-28485. ⟨10.3390/ijms161226110⟩
Journal articles lirmm-01286570v1

Closed form modeling of evolutionary rates by exponential Brownian functionals

Nicolas Privault , Stéphane Guindon
Journal of Mathematical Biology, 2015, 71 (6), pp.1387-1409. ⟨10.1007/s00285-015-0863-6⟩
Journal articles lirmm-01233099v1

How well can the exponential-growth coalescent approximate constant-rate birth-death population dynamics?

Tanja Stadler , Timothy G. Vaughan , Alex Gavryushkin , Stéphane Guindon , Denise Kühnert
Proceedings of the Royal Society B: Biological Sciences, 2015, 282 (1806), pp.20150420. ⟨10.1098/rspb.2015.0420⟩
Journal articles lirmm-01349044v1
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Modelling Competition and Dispersal in a Statistical Phylogeographic Framework

Louis Ranjard , David Welch , Marie Paturel , Stéphane Guindon
Systematic Biology, 2014, 63 (5), pp.743-752. ⟨10.1093/sysbio/syu040⟩
Journal articles lirmm-01233106v1
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From Trajectories to Averages: An Improved Description of the Heterogeneity of Substitution Rates Along Lineages

Stéphane Guindon
Systematic Biology, 2013, 62 (1), pp.22-34. ⟨10.1093/sysbio/sys063⟩
Journal articles lirmm-00805052v1

Cumulative viral evolutionary changes in chronic hepatitis B virus infection precedes hepatitis B e antigen seroconversion

Stéphane Guindon , Yan Cheng , Allen Rodrigo , Lin Wing Wee , Inoue Masafumi
Gut, 2012, 62 (9), pp.1347-1355. ⟨10.1136/gutjnl-2012-302408⟩
Journal articles lirmm-00805051v1
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PartitionFinder: Combined Selection of Partitioning Schemes and Substitution Models for Phylogenetic Analyses

Stéphane Guindon , Robert Lanfear , Brett Calcott , Simon Y.W. Ho
Molecular Biology and Evolution, 2012, 29 (6), pp.1695-1701. ⟨10.1093/molbev/mss020⟩
Journal articles lirmm-00705211v1
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The Influence of Rate Heterogeneity among Sites on the Time Dependence of Molecular Rates

Julien Soubrier , Mike Steel , Michael S.Y. Lee , Clio Der Sarkissian , Stéphane Guindon
Molecular Biology and Evolution, 2012, 29 (11), pp.3345-3358. ⟨10.1093/molbev/mss140⟩
Journal articles lirmm-00805053v1
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Bayesian Estimation of Divergence Times From Large Sequence Alignments

Stéphane Guindon
Molecular Biology and Evolution, 2010, 27 (8), pp.1768-1781. ⟨10.1093/molbev/msq060⟩
Journal articles lirmm-00705189v1
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SeaView Version 4: a Multiplatform Graphical User Interface for Sequence Alignment and Phylogenetic Tree Building

Manolo Gouy , Stéphane Guindon , Olivier Gascuel
Molecular Biology and Evolution, 2010, 27, pp.221-224. ⟨10.1093/molbev/msp259⟩
Journal articles lirmm-00511794v2
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New Algorithms and Methods to Estimate Maximum-Likelihood Phylogenies: Assessing the Performance of PhyML 3.0

Stéphane Guindon , Jean-François Dufayard , Vincent Lefort , Maria Anisimova , Wim Hordijk
Systematic Biology, 2010, 59 (3), pp.307-321. ⟨10.1093/sysbio/syq010⟩
Journal articles lirmm-00511784v2
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Phylogeny.fr: robust phylogenetic analysis for the non-specialist

Alexis Dereeper , Valentin Guignon , Guillaume Blanc , Stéphane Audic , Sylvain Buffet
Nucleic Acids Research, 2008, 36 (Web Server), pp.W465-W469. ⟨10.1093/nar/gkn180⟩
Journal articles lirmm-00324099v1
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Genomics, biogeography, and the diversification of placental mammals

Derek E. Wildman , Monica Uddin , Juan C. Opazo , Guozhen Liu , Vincent Lefort
Proceedings of the National Academy of Sciences of the United States of America, 2007, 104 (36), pp.14395-14400. ⟨10.1073/pnas.0704342104⟩
Journal articles lirmm-00193171v1
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Identification of NF-kappaB Responsive Elements in Follistatin Related Gene (FLRG) Promoter

Laurent Bartholin , Stéphane Guindon , Sylvie Martel , Laura Corbo , Ruth Rimokh
Gene, 2007, 393, pp.153-162. ⟨10.1016/j.gene.2007.02.007⟩
Journal articles lirmm-00171207v2
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Control of the False Discovery Rate Applied to the Detection of Positively Selected Amino Acid Sites

Stéphane Guindon , Mik Black , Allen Rodrigo
Molecular Biology and Evolution, 2006, 23 (5), pp.919-926. ⟨10.1093/molbev/msj095⟩
Journal articles lirmm-00135171v1
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PHYML Online: A Web Server for Fast Maximum Likelihood-Based Phylogenetic Inference

Stéphane Guindon , F. Le Thiec , Patrice Duroux , Olivier Gascuel
Nucleic Acids Research, 2005, 33, pp.557-559. ⟨10.1093/nar/gki352⟩
Journal articles lirmm-00105317v1

Modeling the Site-Specific Variation of Selection Patterns Along Lineages

Stéphane Guindon , Allen Rodrigo , Kelly Dyer , John Huelsenbeck
Proceedings of the National Academy of Sciences of the United States of America, 2004, 101, pp.12957-12962. ⟨10.1073/pnas.0402177101⟩
Journal articles lirmm-00171208v1
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A Simple, Fast, and Accurate Method to Estimate Large Phylogenies by Maximum Likelihood

Stéphane Guindon , Olivier Gascuel
Systematic Biology, 2003, 52 (5), pp.696-704. ⟨10.1080/10635150390235520⟩
Journal articles lirmm-00191949v1
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Efficient Based Estimation of Evolutionary Distance when Substitution Rates Vary Across Sites

Stéphane Guindon , Olivier Gascuel
Molecular Biology and Evolution, 2002, 19 (4), pp.534-543. ⟨10.1093/oxfordjournals.molbev.a004109⟩
Journal articles lirmm-00268454v1
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Intragenomic base content variation is a potential source of biases when searching for horizontally transferred genes

Stéphane Guindon , G. Perrière
Molecular Biology and Evolution, 2001, 18 (9), pp.1838-1840. ⟨10.1093/oxfordjournals.molbev.a003972⟩
Journal articles hal-00427178v1
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Arbres : combinatoire et modèles

Gilles Didier , Stéphane Guindon
Modèles et méthodes pour l’évolution biologique, iSTE Edition, pp.7-32, 2022, 9781789480696. ⟨10.51926/ISTE.9069.ch1⟩
Book sections hal-03485566v1

Numerical Optimization Techniques in Maximum Likelihood Tree Inference

Stéphane Guindon , Olivier Gascuel
Tandy Warnow. Bioinformatics and Phylogenetics: Seminal Contributions of Bernard Moret, 29, Springer, pp.21-38, 2019, Computational Biology (COBO), 978-3-030-10837-3. ⟨10.1007/978-3-030-10837-3_2⟩
Book sections pasteur-02405302v1
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Estimating maximum likelihood phylogenies with PhyML

Stéphane Guindon , Frédéric Delsuc , Jean-François Dufayard , Olivier Gascuel
David Posada. Bioinformatics for DNA Sequence Analysis, 537, Springer Protocols, pp.113-137, 2009, Methods in Molecular Biology, ⟨10.1007/978-1-59745-251-9_6⟩
Book sections lirmm-00511830v1

Modelling the Variability of Evolutionary Processes

Olivier Gascuel , Stéphane Guindon
Olivier Gascuel; M. Steel. Reconstructing Evolution: New Mathematical and Computational Advances, II Models of sequence evolution, pp.65-99, 2007, 0199208220
Book sections lirmm-00171206v1
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Méthodes et algorithmes pour l'approche statistique en phylogénie

Stéphane Guindon
Bio-Informatique, Biologie Systémique [q-bio.QM]. Université Montpellier II - Sciences et Techniques du Languedoc, 2003. Français. ⟨NNT : ⟩
Theses tel-00843343v1