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Stéphane GUYOT

Researcher identifiers
  • IdHAL stephane-guyot
  • ResearcherId : A-3482-2012
  • ORCID 0000-0002-2316-234X
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  • IdRef : 124704298
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Dr Stéphane GUYOT Lecturer UMR PAM, team PMB – L’Institut Agro Dijon – Université de Bourgogne Franche-Comté 1, Esplanade Érasme 21000 Dijon, France +33 (0)3 80 77 23 87 or **1) Situation** Nationality: French and Swiss Date of birth: 23rd August 1977 Marital status: married, 4 children **2) Education and Career** *Education* 2020 HDR, University of Burgundy Franche-Comté (Dijon, France) 2002-2007 Ph D, ENSBANA, University of Burgundy (Dijon) 2001-2002 Master 2 Research of Food Sciences, University of Burgundy 1999-2000 Master 1 of Cellular and Physiological Biology, University of Burgundy 1998-1999 Bachelor of Science in Cellular and Physiological Biology, University of Burgundy 1995-1997 Technical Degree in Biological and Biochemical Analysis, University of Burgundy *Career* 2008-present Lecturer: Microbiological and Food Processes, L’Institut Agro Dijon (France) 2007-2008 Teacher-Researcher (temporary, 50%), ENSBANA, University of Burgundy 2005-2006 Teacher-Researcher (temporary, 50%), ENSBANA, University of Burgundy 2003-2005 High-education teacher, ENSBANA, University of Burgundy Main field of research: Study of microorganism (pathogenic bacteria, yeasts and viruses) stress response to improve food processes (as destruction of undesired microorganisms). • Design of endogenous fluorescent biomarkers based on transcriptomic and physiological approaches to better understand the stress response and to enhance the conduct of food processes • Development of processes to fight against foodborne pathogens (bacteria and viruses) *Responsabilities (most significant) / scientific activities* 09/2024-present Deputy head of the "Engineering and process sciences" teaching department (Institut Agro Dijon, France) 09/2018-08/2026 Expert for ANSES in the food biohazard comitee 02/2018 Coordinator of the national workshop “Fight against pathogenic and alteration flora” (Dijon, France) 01/2016-present One of the three heads of the International Research Master “Microbiology and Physicochemitry for Food and Wine Processes (MP²)” 01/2017-10/2018 Co-deputy then Deputy Head of the “Procédés Microbiologiques et Biotechnologiques” research team (UMR PAM) 04/2016-present Co-responsible of a transversal research area (UMR PAM) 2012-2015 Head of the 2 years preparatory classes (integrated in AgroSup Dijon) 2012-2013 Young doctor expert for AERES (evaluation of doctoral schools in Life Sciences at Paris 6, France) 2008-2017 Reviewer for international peer-reviewed scientific journals: 13 papers 2014-present Examiner in 4 thesis juries **2) Scientific production ** • Coordinator of a national research program funded by ANR (2024-2028) (7 partners) • 38 articles published in peer-reviewed international scientific journals • International congresses: 7 oral presentations (including 1 invited) + 16 written presentations • National congresses: 9 oral presentations (including 1 invited) + 14 written presentations • Regional congresses: 1 oral presentation + 7 written presentations • Local seminar: 3 oral presentations abroad + 1 oral presentation in France **3) Co-supervision** • Thesis: 2 thesis co-supervised in 2013-2016 (ANR EcoSec 33% and CIFRE: 50%), 1 thesis co-supervised in 2016-2019 (MESR grant: 50%), 2 thesis co-supervised in 2022-2025 (MESR grant: 50%, BFC region: 50%) • Postdoctoral training: 2 postdoctoral researchers supervised (100% each, 2015 and 2016) • Master 2 Research: 16 students co-supervised (1x100% and 15 x 50%)


Biological and physico-chemical characterization of human norovirus-like particles under various environmental conditions

Nicole Abou-Hamad , Marie Estienney , Rémi Chassagnon , Marjorie Bon , Philippe Daval-Frerot
Colloids and Surfaces B: Biointerfaces, 2023, 231, pp.113545. ⟨10.1016/j.colsurfb.2023.113545⟩
Journal articles hal-04229196v1

The Yin-Yang of the Green Fluorescent Protein: Impact on Saccharomyces cerevisiae stress resistance

Mélanie Ragon , Lucie Bertheau , Jennifer Dumont , Tiffany Bellanger , Marie Grosselin
Journal of Photochemistry and Photobiology B: Biology, 2023, 238, pp.112603. ⟨10.1016/j.jphotobiol.2022.112603⟩
Journal articles hal-03902943v1
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Experimental evolution forcing Oenococcus oeni acid tolerance highlights critical role of the citrate locus

Frédérique Julliat , Camille Eicher , Nezha Tourti , Philippe Glaser , Nicolas Cabanel
Research in Microbiology, 2023, 174 (5), pp.104048. ⟨10.1016/j.resmic.2023.104048⟩
Journal articles hal-04034609v1
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The potential of microorganisms as biomonitoring and bioremediation tools for mercury-contaminated soils

Lorraine Meyer , Stéphane Guyot , Michel Chalot , Nicolas Capelli
Ecotoxicology and Environmental Safety, 2023, 262, pp.115185. ⟨10.1016/j.ecoenv.2023.115185⟩
Journal articles hal-04152835v1
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Management of Listeria monocytogenes on Surfaces via Relative Air Humidity: Key Role of Cell Envelope

Fiona Zoz , Stéphane Guyot , Cosette Grandvalet , Mélanie Ragon , Eric Lesniewska
Foods, 2021, 10 (9), pp.1-15. ⟨10.3390/foods10092002⟩
Journal articles hal-03327279v1
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Increased xerotolerance of Saccharomyces cerevisiae during an osmotic pressure ramp over several generations

Stéphane Guyot , Laurence Pottier , Lucie Bertheau , Jennifer Dumont , Eminence Dorelle Hondjuila Miokono
Microbial Biotechnology, 2021, 14 (4), pp.1445-1461. ⟨10.1111/1751-7915.13789⟩
Journal articles hal-03174738v1
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Cardiolipin content controls mitochondrial coupling and energetic efficiency in muscle

Alexandre Prola , Jordan Blondelle , Aymeline Vandestienne , Jérôme Piquereau , Raphaël Denis
Science Advances , 2021, 7 (1), pp.eabd6322. ⟨10.1126/sciadv.abd6322⟩
Journal articles hal-03105418v1
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Highlighting Protective Effect of Encapsulation on Yeast Cell Response to Dehydration Using Synchrotron Infrared Microspectroscopy at the Single-Cell Level

Thanh Dat Nguyen , Stéphane Guyot , Caroline Pénicaud , Stéphanie Passot , Christophe Sandt
Frontiers in Microbiology, 2020, 11 (6), pp.1887. ⟨10.3389/fmicb.2020.01887⟩
Journal articles hal-02939385v1
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Estimation of Microbial Viability Using Flow Cytometry

Hazel Davey , Stéphane Guyot
Current Protocols in Cytometry, 2020, 93 (1), pp.1-13. ⟨10.1002/cpcy.72⟩
Journal articles hal-02544120v1

Automatic Counting of Intra-Cellular Ribonucleo-Protein Aggregates in Saccharomyces cerevisiae Using a Textural Approach

Ambroise Marin , Emmanuel Denimal , Lucie Bertheau , Stéphane Guyot , Ludovic Journaux
Microscopy and Microanalysis, 2019, 25 (1), pp.164-179. ⟨10.1017/S1431927619000084⟩
Journal articles hal-02171876v1
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Cellular Injuries in Cronobacter sakazakii CIP 103183T and Salmonella enterica Exposed to Drying and Subsequent Heat Treatment in Milk Powder

Emilie Lang , Stéphane Guyot , Caroline Peltier , Pablo Alvarez-Martin , Jean-Marie Perrier-Cornet
Frontiers in Microbiology, 2018, 9, pp.475. ⟨10.3389/fmicb.2018.00475⟩
Journal articles hal-01907589v1

Listeria monocytogenes ability to survive desiccation: Influence of serotype, origin, virulence, and genotype

Fiona Zoz , Cosette Grandvalet , Emilie Lang , Cyril Laconelli , Patrick Gervais
International Journal of Food Microbiology, 2017, 248, pp.82 - 89. ⟨10.1016/j.ijfoodmicro.2017.02.010⟩
Journal articles hal-01509875v1

Influence of the air humidity on the drying of a liquid droplet on a solid plate and on bacterial destruction

Onrawee Laguerre , L. Lecoq , F. Zoz , Stéphane Guyot , Laurent Beney
Journal of Food Engineering, 2017, 212, pp.76-86. ⟨10.1016/j.jfoodeng.2017.05.014⟩
Journal articles hal-01558465v1

Caco-2 Invasion by Cronobacter sakazakii and Salmonella enterica Exposed to Drying and Heat Treatments in Dried State in Milk Powder

Émilie Lang , Stéphane Guyot , Pablo Alvarez-Martin , Jean-Marie Perrier-Cornet , Patrick Gervais
Frontiers in Microbiology, 2017, 8, ⟨10.3389/fmicb.2017.01893⟩
Journal articles hal-01618841v1

Comparison of the effects of major fatty acids present in the Mediterranean diet (oleic acid, docosahexaenoic acid) and in hydrogenated oils (elaidic acid) on 7-ketocholesterol-induced oxiapoptophagy in microglial BV-2 cells

Meryam Debbabi , Amira Zarrouk , Maryem Bezine , Wiem Meddeb , Thomas Nury
Chemistry and Physics of Lipids, 2017, 207 (Pt B), pp.151-170. ⟨10.1016/j.chemphyslip.2017.04.002⟩
Journal articles hal-01912331v1

Modeling the heat inactivation of foodborne pathogens in milk powder : High relevance of the substrate water activity

Emilie Lang , Layla Chemlal , Paul Molin , Stéphane Guyot , Pablo Alvarez-Martin
Food Research International, 2017, 99 (1), pp.577-585. ⟨10.1016/j.foodres.2017.06.028⟩
Journal articles hal-01558447v1

Drying parameters greatly affect the destruction of Cronobacter sakazakii and Salmonella Typhimurium in standard buffer and milk

Emilie Lang , Cyril Laconelli , Fiona Zoz , Stéphane Guyot , Pablo Alvarez-Martin
Food Microbiology, 2017, 62, pp.82 - 91. ⟨10.1016/⟩
Journal articles hal-01509615v1

Understanding the responses of Saccharomyces cerevisiae yeast strain during dehydration processes using synchrotron infrared spectroscopy

T. Nguyen , Stéphane Guyot , Caroline Pénicaud , S. Passot , C. Sandt
Analyst, 2017, 142 (19), pp.3620 - 3628. ⟨10.1039/c7an00257b⟩
Journal articles hal-01616052v1

Automatic Biological Cell Counting Using a Modified Gradient Hough Transform

Emmanuel Denimal , Ambroise Marin , Stéphane Guyot , Ludovic Journaux , Paul Molin
Microscopy and Microanalysis, 2017, 23 (01), pp.11 - 21. ⟨10.1017/S1431927616012617⟩
Journal articles hal-01509941v1

Design of new sensitive α,β-unsaturated carbonyl 1,8-naphtalimide fluorescent probes for thiol bioimaging

Nicolas Sok , Maria Nikolantonaki , Stéphane Guyot , Thanh Dat Nguyen , Anne-Sophie Viaux
Sensors and Actuators B: Chemical, 2017, 242, pp.865 - 871. ⟨10.1016/j.snb.2016.09.171⟩
Journal articles hal-01509840v1

Recovery Estimation of Dried Foodborne Pathogens Is Directly Related to Rehydration Kinetics

Émilie Lang , Fiona Zoz , Cyril Laconelli , Stéphane Guyot , Pablo Alvarez-Martin
PLoS ONE, 2016, 11 (8), ⟨10.1371/journal.pone.0160844⟩
Journal articles hal-01466823v1

An Off-On-Off Fluorescent Sensor for pH Windows Based on the 13aneN4-Zn 2+ System

Valeria Amendola , Greta Bergamaschi , Giacomo Dacarro , Franck Denat , Frederic Boschetti
European Journal of Inorganic Chemistry, 2016, 2016 (32), pp.5106 - 5113. ⟨10.1002/ejic.201600749⟩
Journal articles hal-01492871v1

Innovative High Gas Pressure Microscopy Chamber Designed for Biological Cell Observation

Mélanie Ragon , Hue Nguyen Thi Minh , Stéphane Guyot , Pauline Loison , Gaëtan Burgaud
Microscopy and Microanalysis, 2016, 22 (01), pp.63 - 70. ⟨10.1017/S1431927615015639⟩
Journal articles hal-01485208v1

Control of Relative Air Humidity as a Potential Means to Improve Hygiene on Surfaces: A Preliminary Approach with Listeria monocytogenes

Fiona Zoz , Cyril Laconelli , Émilie Lang , Stéphane Guyot , Cosette Grandvalet
PLoS ONE, 2016, 11 (2), ⟨10.1371/journal.pone.0148418⟩
Journal articles hal-01466198v1

Protection of yeast cells in micro-organized shells of natural polyelectrolytes during drying process

Thanh Dat Nguyen , Stéphane Guyot , Christophe Sandt , Caroline Pénicaud , Stéphanie Passot
STP Pharma Pratiques, 2016, 26 (2), pp.133
Journal articles hal-01531646v1

Reliable Detection and Smart Deletion of Malassez Counting Chamber Grid in Microscopic White Light Images for Microbiological Applications

Emmanuel Denimal , Ambroise Marin , Ludovic Journaux , Stéphane Guyot , Paul Molin
Microscopy and Microanalysis, 2015, pp.1-7. ⟨10.1017/S1431927615000665⟩
Journal articles hal-01164294v1

Surviving the heat: heterogeneity of response in S accharomyces cerevisiae provides insight into thermal damage to the membrane

Stéphane Guyot , Patrick Gervais , Michael Young , Pascale Winckler , Jennifer Dumont
Environmental Microbiology, 2015, 17 (8), pp.2982-2992. ⟨10.1111/1462-2920.12866⟩
Journal articles hal-02290604v1

A Robust Generic Method for Grid Detection in White Light Microscopy Malassez Blade Images in the Context of Cell Counting

Ambroise Marin , Emmanuel Denimal , Stéphane Guyot , Ludovic Journaux , Paul Molin
Microscopy and Microanalysis, 2015, 21 (01), pp.239-248. ⟨10.1017/S1431927614013671⟩
Journal articles hal-01114543v1

Protection of living yeast cells by micro-organized shells of natural polyelectrolytes

Thanh Dat Nguyen , Stéphane Guyot , Jeannine Lherminier , Yves Waché , Rémi Saurel
Process Biochemistry, 2015, 50 (10), pp.1528-1536. ⟨10.1016/j.procbio.2015.06.003⟩
Journal articles hal-02290612v1

Hydrodynamic characterization of a new small-scale reactor mixed by a magnetic bar

Charline Allonneau , Eric Olmos , Stéphane Guyot , Eric Ferret , Patrick Gervais
Biochemical Engineering Journal, 2015, 96, pp.29-37. ⟨10.1016/j.bej.2014.12.005⟩
Journal articles hal-01267213v1
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HACD1 , a regulator of membrane composition and fluidity, promotes myoblast fusion and skeletal muscle growth

Jordan Blondelle , Yusuke Ohno , Vincent Gache , Stéphane Guyot , Sébastien Storck
Journal of molecular cell biology, 2015, 7 (5), pp.429-440. ⟨10.1093/jmcb/mjv049⟩
Journal articles hal-02290631v1
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Extremely rapid acclimation of Escherichia coli to high temperature over a few generations of a fed-batch culture during slow warming

Stéphane Guyot , Laurence Pottier , Alain Hartmann , Mélanie Ragon , Julia Hauck Tiburski
MicrobiologyOpen, 2014, 3 (1), pp.52-63. ⟨10.1002/mbo3.146⟩
Journal articles hal-02290963v1

Water Distribution in Bacterial Spores: A Key Factor in Heat Resistance

Julia Hauck Tiburski , Amauri Rosenthal , Stéphane Guyot , Jean-Marie Perrier-Cornet , Patrick Gervais
Food Biophysics, 2014, 9 (1), pp.10-19. ⟨10.1007/s11483-013-9312-5⟩
Journal articles hal-02290639v1

Exploration of Lipid Metabolism in Relation with Plasma Membrane Properties of Duchenne Muscular Dystrophy Cells: Influence of L-Carnitine

Françoise Le Borgne , Stéphane Guyot , Morgan Logerot , Laurent Beney , Patrick Gervais
PLoS ONE, 2012, 7 (11), pp.e49346. ⟨10.1371/journal.pone.0049346⟩
Journal articles hal-02291000v1

Physiological responses of Escherichia coli exposed to different heat-stress kinetics

Stéphane Guyot , Laurence Pottier , Eric Ferret , Laurent Gal , Patrick Gervais
Archives of Microbiology, 2010, 192 (8), pp. 651 - 661. ⟨10.1007/s00203-010-0597-1⟩
Journal articles hal-01789685v1

Phospholipidosis and down-regulation of the PI3-K/PDK-1/Akt signalling pathway are vitamin E inhibitable events associated with 7-ketocholesterol-induced apoptosis

Anne Vejux , Stéphane Guyot , Thomas Montange , Jean-Marc Riedinger , Edmond Kahn
The Journal of Nutritional Biochemistry, 2009, 20 (1), pp.45-61. ⟨10.1016/j.jnutbio.2007.12.001⟩
Journal articles hal-02291044v1

Erratum to: Effect of the osmotic conditions during sporulation on the subsequent resistance of bacterial spores

Hue Nguyen Thi Minh , Stéphane Guyot , Jean-Marie Perrier-Cornet , Patrick Gervais
Applied Microbiology and Biotechnology, 2008, 80 (1), pp.107-114. ⟨10.1007/s00253-008-1519-x⟩
Journal articles hal-02291056v1

Yeast cell inactivation related to local heating induced by low-intensity electric fields with long-duration pulses

Stéphane Guyot , Eric Ferret , Jean-Baptiste Boehm , Patrick Gervais
International Journal of Food Microbiology, 2007, 113 (2), pp.180-188. ⟨10.1016/j.ijfoodmicro.2006.06.036⟩
Journal articles hal-02291104v1

Yeast Survival during Thermal and Osmotic Shocks Is Related to Membrane Phase Change

Stéphane Guyot , Eric Ferret , Patrick Gervais
Journal of Agricultural and Food Chemistry, 2006, 54 (22), pp.8450-8455. ⟨10.1021/jf0620158⟩
Journal articles hal-02291112v1

Responses of Saccharomyces cerevisiae to thermal stress

Stéphane Guyot , Eric Ferret , Patrick Gervais
Biotechnology and Bioengineering, 2005, 92 (4), pp.403-409. ⟨10.1002/bit.20600⟩
Journal articles hal-02295180v1

The Impact of Drying on Foodborne Pathogens Salmonella enterica and Cronobacter sakazakii

Emilie Lang , Stéphane Guyot , Pablo Alvarez-Martin , Jean-Marie Perrier-Cornet , Patrick Gervais
IAFP's 13th European Symposium on Food Safety, Mar 2017, Brussels, Belgium
Conference papers hal-01533452v1

High gas pressure survival/reactivation of soil microorganisms

Mélanie Ragon , Stéphane Guyot , Jean-Marie Perrier-Cornet , Alain Hartmann , Patrick Gervais
8th International Conference on High Pressure Bioscience and Biotechnology (HPBB 2014), Jul 2014, Nantes, France
Conference papers hal-02481090v1

Survie et/ou réactivation de microorganismes du sol sous hautes pressions gazeuses

Mélanie Ragon , Stéphane Guyot , Jean-Marie Perrier-Cornet , Alain Hartmann , Patrick Gervais
Workshop "interactions des miccrooganismes avec leurs environnements : adaptation, circulation", Jun 2012, Dijon, France
Conference papers hal-02481121v1
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Survie et/ou réactivation de microorganismes du sol sous hautes pressions gazeuses

Mélanie Ragon , Stéphane Guyot , Jean-Marie Perrier-Cornet , Alain Hartmann , Patrick Gervais
Workshop Interactions des Microorganismes avec leurs Environnements : Circulation, Adaptation, Jun 2012, Dijon, France
Conference papers hal-02746507v1