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Dysregulated expression of cholesterol biosynthetic genes in Alzheimer's disease alters epigenomic signatures of hippocampal neurons
I. Paiva
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J. Seguin
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I. Grgurina
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A. K. Singh
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Article dans une revue
hal-04686940
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RNA polymerase II transcription initiation in holo-TFIID-depleted mouse embryonic stem cells
Vincent Hisler
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Paul Bardot
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Dylane Detilleux
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Andrea Bernardini
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Matthieu Stierle
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Article dans une revue
inserm-04714824
v1
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Mutant FUS induces chromatin reorganization in the hippocampus and alters memory processes
Laura Tzeplaeff
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Jonathan Seguin
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Stéphanie Le Gras
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Salim Megat
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Brigitte Cosquer
et al.
Article dans une revue
hal-04714491
v1
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Super-enhancer-driven expression of BAHCC1 promotes melanoma cell proliferation and genome stability
Pietro Berico
,
Maguelone Nogaret
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Max Cigrang
,
Antonin Lallement
,
Fatemeh Vand-Rajabpour
et al.
Article dans une revue
hal-04739149
v1
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Super-enhancer-driven expression of BAHCC1 promotes melanoma cell proliferation and genome stability
Pietro Berico
,
Maguelone Nogaret
,
Max Cigrang
,
Antonin Lallement
,
Fatemeh Vand-Rajabpour
et al.
Article dans une revue
hal-04398947
v1
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Multi-Omics Data Integration Reveals Sex-Dependent Hippocampal Programming by Maternal High-Fat Diet during Lactation in Adult Mouse Offspring
Thibaut Gauvrit
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Hamza Benderradji
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Alexandre Pelletier
,
Soulaimane Aboulouard
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Emilie Faivre
et al.
Article dans une revue
hal-04398934
v1
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Analysis of the P. lividus sea urchin genome highlights contrasting trends of genomic and regulatory evolution in deuterostomes
Ferdinand Marlétaz
,
Arnaud Couloux
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Julie Poulain
,
Karine Labadie
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Corinne da Silva
et al.
Article dans une revue
(data paper)
hal-04093287
v1
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Mitotic chromosome condensation resets chromatin to safeguard transcriptional homeostasis during interphase
Lucía Ramos-Alonso
,
Petter Holland
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Stéphanie Le Gras
,
Xu Zhao
,
Bernard Jost
et al.
Article dans une revue
hal-04098268
v1
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MBD4 loss results in global reactivation of promoters and retroelements with low methylated CpG density
Christophe Papin
,
Abdulkhaleg Ibrahim
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Jamal Sabir
,
Stéphanie Le Gras
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Isabelle Stoll
et al.
Article dans une revue
hal-04288047
v1
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Dual role of histone variant H3.3B in spermatogenesis: positive regulation of piRNA transcription and implication in X-chromosome inactivation
Emeline Fontaine
,
Christophe Papin
,
Guillaume Martinez
,
Stéphanie Le Gras
,
Roland Abi Nahed
et al.
Article dans une revue
hal-03852700
v1
|
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Istradefylline protects from cisplatin-induced nephrotoxicity and peripheral neuropathy while preserving cisplatin antitumor effects
Edmone Dewaeles
,
Kévin Carvalho
,
Sandy Fellah
,
Jaewon Sim
,
Nihad Boukrout
et al.
Article dans une revue
inserm-03865945
v1
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Caffeine intake exerts dual genome-wide effects on hippocampal metabolism and learning-dependent transcription
Isabel Paiva
,
Lucrezia Cellai
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Céline Meriaux
,
Lauranne Poncelet
,
Ouada Nebie
et al.
Article dans une revue
hal-03855350
v1
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Polyglutamine-expanded ATXN7 alters a specific epigenetic signature underlying photoreceptor identity gene expression in SCA7 mouse retinopathy
Anna Niewiadomska-Cimicka
,
Antoine Hache
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Stéphanie Le Gras
,
Céline Keime
,
Tao Ye
et al.
Article dans une revue
hal-03935562
v1
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TRIM28-dependent SUMOylation protects the adult ovary from activation of the testicular pathway
Moïra Rossitto
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Stephanie Déjardin
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Chris M Rands
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Stephanie Le Gras
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Roberta Migale
et al.
Article dans une revue
hal-03746540
v1
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Waves of sumoylation support transcription dynamics during adipocyte differentiation
Xu Zhao
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Ivo A Hendriks
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Stéphanie Le Gras
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Tao Ye
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Lucía Ramos-Alonso
et al.
Article dans une revue
hal-03716138
v1
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CDK7 and MITF repress a transcription program involved in survival and drug tolerance in melanoma
Pietro Berico
,
Max Cigrang
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Guillaume Davidson
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Cathy Braun
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Jeremy Sandoz
et al.
Article dans une revue
inserm-03336903
v1
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Polycystic ovary syndrome is transmitted via a transgenerational epigenetic process
Nour El Houda Mimouni
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Isabel Paiva
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Anne-Laure Barbotin
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Fatima Ezzahra Timzoura
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Damien Plassard
et al.
Article dans une revue
hal-04161337
v1
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Helios represses megakaryocyte priming in hematopoietic stem and progenitor cells
Giovanni Cova
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Chiara Taroni
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Marie-Céline Deau
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Qi Cai
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Vincent Mittelheisser
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Article dans une revue
hal-03375832
v1
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CpG Islands Shape the Epigenome Landscape
Christophe Papin
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Stéphanie Le Gras
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Abdulkhaleg Ibrahim
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Hatem Salem
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Mohammad Mahdi Karimi
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Article dans une revue
hal-03450118
v1
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MeCP2 is a microsatellite binding protein that protects CA repeats from nucleosome invasion
Abdulkhaleg Ibrahim
,
Christophe Papin
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Kareem Mohideen-Abdul
,
Stéphanie Le Gras
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Isabelle Stoll
et al.
Article dans une revue
inserm-03376640
v1
|
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Succinylation of H3K122 destabilizes nucleosomes and enhances transcription
Lara Zorro Shahidian
,
Mariska Haas
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Stéphanie Le Gras
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Sandra Nitsch
,
André Mourão
et al.
Article dans une revue
hal-03713626
v1
|
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Polycystic ovary syndrome is transmitted via a transgenerational epigenetic process
Nour El Houda Mimouni
,
Isabel Paiva
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Anne Laure Barbotin
,
Fatima Ezzahra Timzoura
,
Damien Plassard
et al.
Article dans une revue
hal-03427354
v1
|
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Sequential actions of EOMES and T-BET promote stepwise maturation of natural killer cells
Jiang Zhang
,
Stéphanie Le Gras
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Kevin Pouxvielh
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Fabrice Faure
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Lucie Fallone
et al.
Article dans une revue
hal-03357265
v1
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Correction: Ikaros antagonizes DNA binding by STAT5 in pre-B cells
Beate Heizmann
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Stéphanie Le Gras
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Célestine Simand
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Patricia Marchal
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Susan Chan
et al.
Article dans une revue
hal-03665603
v2
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Heterochromatin establishment during early mammalian development is regulated by pericentromeric RNA and characterized by non-repressive H3K9me3
Adam Burton
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Vincent Brochard
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Carmen Galán
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Elias Ruiz-Morales
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Quirze Rovira
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Article dans une revue
hal-02903653
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Cell-Type-Specific Gene Expression Profiling in Adult Mouse Brain Reveals Normal and Disease-State Signatures
Nicolas Merienne
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Cécile Meunier
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Anne Schneider
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Jonathan Seguin
,
Satish Nair
et al.
Article dans une revue
hal-02087719
v1
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Exacerbation of C1q dysregulation, synaptic loss and memory deficits in tau pathology linked to neuronal adenosine A2A receptor
Kevin Carvalho
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Emilie Faivre
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Marie Pietrowski
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Xavier Marques
,
Victoria Gomez-Murcia
et al.
Article dans une revue
inserm-02350065
v1
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Genes and Pathways Regulated by Androgens in Human Neural Cells, Potential Candidates for the Male Excess in Autism Spectrum Disorder
Angélique Quartier
,
Laure Chatrousse
,
Claire Redin
,
Céline Keime
,
Nicolas Haumesser
et al.
Article dans une revue
hal-03670936
v1
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Genes and Pathways Regulated by Androgens in Human Neural Cells, Potential Candidates for the Male Excess in Autism Spectrum Disorder
Angélique Quartier
,
Laure Chatrousse
,
Claire Redin
,
Céline Keime
,
Nicolas Haumesser
et al.
Article dans une revue
hal-04404908
v1
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La médiation corporelle dans la prise en charge globale de jeunes souffrant d’anorexie mentale
Catherine Saez
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Laurence Suelves
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Marie Deguitre
,
Blandine Deffinis
,
Marie-Jeanne Calmels
et al.
Article dans une revue
hal-02316819
v1
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Reinstating plasticity and memory in a tauopathy mouse model with an acetyltransferase activator
Snehajyoti Chatterjee
,
Raphaelle Cassel
,
Anne Schneider‐anthony
,
Karine Mérienne
,
Brigitte Cosquer
et al.
Article dans une revue
inserm-01930486
v1
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MAPK-triggered chromatin reprogramming by histone deacetylase in plant innate immunity
David Latrasse
,
Teddy Jegu
,
Huchen Li
,
Axel de Julien de Zelicourt
,
Cécile Raynaud
et al.
Article dans une revue
hal-02627216
v1
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TEAD transcription factors are required for normal primary myoblast differentiation in vitro and muscle regeneration in vivo
Shilpy Joshi
,
Guillaume Davidson
,
Stéphanie Le Gras
,
Shuichi Watanabe
,
Thomas Braun
et al.
Article dans une revue
hal-03524880
v1
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The <em>Arabidopsis</em> SWI/SNF protein BAF60 mediates seedling growth control by modulating DNA accessibility
Teddy Jegu
,
Alaguraj Veluchamy
,
Juan Sebastien Ramirez Prado
,
Charley Rizzi Paillet
,
Magali Perez
et al.
Article dans une revue
hal-02627578
v1
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Intragenic FMR1 disease-causing variants: a significant mutational mechanism leading to Fragile-X syndrome
Angélique Quartier
,
Hélène Poquet
,
Brigitte Gilbert-Dussardier
,
Massimiliano Rossi
,
Anne-Sophie Casteleyn
et al.
Article dans une revue
hal-04542452
v1
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Histone propionylation is a mark of active chromatin
Adam Kebede
,
Anna Nieborak
,
Lara Shahidian
,
Stéphanie Le Gras
,
Florian Richter
et al.
Article dans une revue
hal-03677811
v1
|
|
Altered enhancer transcription underlies Huntington’s disease striatal transcriptional signature
Stéphanie Le Gras
,
Céline Keime
,
Anne Anthony
,
Caroline Lotz
,
Lucie de Longprez
et al.
Article dans une revue
cea-01751880
v1
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Macrophage production and activation are dependent on TRIM33
Anne-Sophie Gallouet
,
Federica Ferri
,
Vanessa Petit
,
Aude Parcelier
,
Daniel Lewandowski
et al.
Article dans une revue
hal-03677820
v1
|
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Combinatorial DNA methylation codes at repetitive elements
Ali Hamiche
,
Christophe Papin
,
Abdulkhaleg Ibrahim
,
Stéphanie Le Gras
,
Amandine Velt
et al.
Article dans une revue
hal-03484320
v1
|
|
Histone propionylation is a mark of active chromatin
Adam Kebede
,
Anna Nieborak
,
Lara Zorro Shahidian
,
Stephanie Le Gras
,
Florian Richter
et al.
Article dans une revue
hal-03985649
v1
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A targeted next-generation sequencing assay for the molecular diagnosis of genetic disorders with orodental involvement
Megana K. Prasad
,
Véronique Geoffroy
,
Serge Vicaire
,
Bernard Jost
,
Michael Dumas
et al.
Article dans une revue
hal-01272929
v1
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Genome-wide mapping of collier In vivo binding sites highlights its hierarchical position in different transcription regulatory networks
Mathilde de Taffin
,
Yannick Carrier
,
Laurence Dubois
,
Laetitia Bataillé
,
Anaïs Painset
et al.
Article dans une revue
hal-02634392
v1
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Transcription factor MITF and remodeller BRG1 define chromatin organisation at regulatory elements in melanoma cells
Patrick Laurette
,
Thomas Strub
,
Dana Koludrovic
,
Céline Keime
,
Stéphanie Le Gras
et al.
Article dans une revue
hal-04238122
v1
|
|
Neuronal identity genes regulated by super-enhancers are preferentially down-regulated in the striatum of Huntington's disease mice
M. Achour
,
S. Le Gras
,
C. Keime
,
F. Parmentier
,
F. Lejeune
et al.
Article dans une revue
hal-02106606
v1
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A Brn2–Zic1 axis specifies the neuronal fate of retinoic-acid-treated embryonic stem cells
Sylvia Urban
,
Dominique Kobi
,
Marie Ennen
,
Diana Langer
,
Stéphanie Le Gras
et al.
Article dans une revue
hal-04217954
v1
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Ikaros mediates gene silencing in T cells through Polycomb repressive complex 2
Attila Oravecz
,
Apostol Apostolov
,
Katarzyna Polak
,
Bernard Jost
,
Stéphanie Le Gras
et al.
Article dans une revue
hal-04248892
v1
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TAF4, a subunit of transcription factor II D, directs promoter occupancy of nuclear receptor HNF4A during post-natal hepatocyte differentiation
Daniil Alpern
,
Diana Langer
,
Benoit Ballester
,
Stephanie Le Gras
,
Christophe Romier
et al.
Article dans une revue
hal-01404987
v1
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|
Efficient strategy for the molecular diagnosis of intellectual disability using targeted high-throughput sequencing
Claire Redin
,
Bénédicte Gérard
,
Julia Lauer
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Yvan Herenger
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Jean Muller
et al.
Article dans une revue
hal-04542582
v1
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The tumor suppressor Ikaros shapes the repertoire of notch target genes in T cells
Anne-Solen Geimer Le Lay
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Attila Oravecz
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Jérôme Mastio
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Claudia Jung
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Patricia Marchal
et al.
Article dans une revue
hal-04248893
v1
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Sumoylation at chromatin governs coordinated repression of a transcriptional program essential for cell growth and proliferation
Hélène Neyret-Kahn
,
Moussa Benhamed
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Tao Ye
,
Stéphanie Le Gras
,
Jack-Christophe Cossec
et al.
Article dans une revue
pasteur-03235077
v1
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An integrated diagnosis strategy for congenital myopathies.
Johann Böhm
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Nasim Vasli
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Edoardo Malfatti
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Stéphanie Le Gras
,
Claire Feger
et al.
Article dans une revue
inserm-00904638
v1
|
|
20 ans après: a second mutation in MAOA identified by targeted high-throughput sequencing in a family with altered behavior and cognition
Amélie Piton
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Hélène Poquet
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Claire Redin
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Alice Masurel
,
Julia Lauer
et al.
Article dans une revue
hal-04970577
v1
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Chromatin signatures and retrotransposon profiling in mouse embryos reveal regulation of LINE-1 by RNA
Anas Fadloun
,
Stéphanie Le Gras
,
Bernard Jost
,
Céline Ziegler-Birling
,
H Takahashi
et al.
Article dans une revue
hal-04119882
v1
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Trim24-repressed VL30 retrotransposons regulate gene expression by producing noncoding RNA
Benjamin Herquel
,
Khalid Ouararhni
,
Igor Martianov
,
Stéphanie Le Gras
,
Tao Ye
et al.
Article dans une revue
hal-04217904
v1
|
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Targeted high-throughput sequencing for diagnosis of genetically heterogeneous diseases: efficient mutation detection in Bardet-Biedl and Alström Syndromes
Claire Redin
,
Stéphanie Le Gras
,
Oussema Mhamdi
,
Véronique Geoffroy
,
Corinne Stoetzel
et al.
Article dans une revue
hal-04542601
v1
|
|
Targeted high-throughput sequencing for diagnosis of genetically heterogeneous diseases: efficient mutation detection in Bardet-Biedl and Alstrom syndromes
Claire Redin
,
Stéphanie Le Gras
,
Oussema Mhamdi
,
Véronique Geoffroy
,
Corinne Stoetzel
et al.
Article dans une revue
hal-04238123
v1
|
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Samaritan myopathy, an ultimately benign congenital myopathy, is caused by a RYR1 mutation
Johann Böhm
,
Esther Leshinsky-Silver
,
Stéphane Vassilopoulos
,
Stéphanie Le Gras
,
Tally Lerman-Sagie
et al.
Article dans une revue
hal-05007113
v1
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|
Next generation sequencing for molecular diagnosis of neuromuscular diseases
Nasim Vasli
,
Johann Böhm
,
Stéphanie Le Gras
,
Jean Muller
,
Cécile Pizot
et al.
Article dans une revue
hal-05004632
v1
|
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Essential role of microphthalmia transcription factor for DNA replication, mitosis and genomic stability in melanoma
T Strub
,
S. Giuliano
,
T Ye
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C Bonet
,
C. Keime
et al.
Article dans une revue
inserm-02530755
v1
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Bcl11b represses a mature T-cell gene expression program in immature CD4(+)CD8(+) thymocytes
Philippe Kastner
,
Susan Chan
,
Walter Vogel
,
Ling-Juan Zhang
,
Acharawan Topark-Ngarm
et al.
Article dans une revue
hal-04009063
v1
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Cell-specific occupancy of an extended repertoire of CREM and CREB binding loci in male germ cells.
Igor Martianov
,
Mohamed-Amin Choukrallah
,
Arnaud Krebs
,
Tao Ye
,
Stephanie Legras
et al.
Article dans une revue
inserm-00663886
v1
|
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Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL
Robin Jeannet
,
Jérôme Mastio
,
Alejandra Macias Garcia
,
Attila Oravecz
,
Todd Ashworth
et al.
Article dans une revue
hal-04065527
v1
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Genome-wide analysis of POU3F2/BRN2 promoter occupancy in human melanoma cells reveals Kitl as a novel regulated target gene
Dominique Kobi
,
Anne-Lise Steunou
,
Doulaye Dembélé
,
Stéphanie Le Gras
,
Lionel Larue
et al.
Article dans une revue
istex
hal-04042071
v1
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A Strategy for Direct Mapping and Identification of Mutations by Whole-Genome Sequencing
Steven Zuryn
,
Stéphanie Le Gras
,
Karine Jamet
,
Sophie Jarriault
Article dans une revue
hal-03036122
v1
|