Thierry Douki

335
Documents

Publications

Publications

Deposit thumbnail

Toxicity of polyethylene terephthalate and polylactic acid nanoplastics, pristine and weathered in environmentally-relevant conditions, to human intestinal cells representative of genetic susceptibility to Crohn's disease

Vérane Bard , Margaux Papin , Maeva Boulée , Marion Berenguer , Aliro Villacorta et al.

Food and Chemical Toxicology, 2026, 212, pp.116027. ⟨10.1016/j.fct.2026.116027⟩

Article dans une revue hal-05546216v1
Deposit thumbnail

Hazard associated with the synthesis of epoxy-vitrimer: In vitro risk assessment and scoring strategy

Marion Berenguer , David Béal , Justine Bétemps , Jade Boudard , Jean-Luc Ravanat et al.

Toxicology in Vitro, 2026, 113, pp.106214. ⟨10.1016/j.tiv.2026.106214⟩

Article dans une revue hal-05519693v1
Deposit thumbnail

Modulation of the Toxicity of Three Red Tattoo Pigments by Artificial Aging

Lise Aubry , Marie Blanchemanche , Lucie Breuillé , Thierry Rabilloud , Thierry Douki

Chemical Research in Toxicology, In press, ⟨10.1021/acs.chemrestox.5c00451⟩

Article dans une revue hal-05522874v1

Changes in ultraviolet a radiation-induced thymidine dimers and erythema after oral nicotinamide or polypodium leucotomos extract in healthy volunteers: a randomized intraindividual trial

Aheen Faisal , C M Lerche , Thierry Douki , P A Philipsen , C. Pihl et al.

Photochemical & Photobiological Sciences , 2026, ⟨10.1007/s43630-026-00884-2⟩

Article dans une revue hal-05568411v1
Deposit thumbnail

Accelerated aging modulates the toxicological properties of the diazo tattoo pigment PO13

Lise Aubry , Marianne Vitipon , Aurélie Hirschler , Hélène Diemer , Thierry Rabilloud et al.

Scientific Reports, 2025, 15 (1), pp.695. ⟨10.1038/s41598-024-83713-9⟩

Article dans une revue hal-04865269v1
Deposit thumbnail

Quantitative HPLC-mass spectrometry analysis shows the drastic impact of the composition of aqueous and biochemical media on the release of soluble hydrolysis products from submicron polycaprolactone

Maëva Boulée , Marie Carrière , Thierry Douki

Polymer, 2025, 339, pp.129150. ⟨10.1016/j.polymer.2025.129150⟩

Article dans une revue hal-05298626v1

Changes in ultraviolet B radiation-induced DNA damage and erythema after oral nicotinamide and polypodium leucotomos in healthy volunteers: an intraindividual controlled trial

A. Faisal , P. Philipsen , C. Lerche , Thierry Douki , F. Laursen et al.

Photochemical & Photobiological Sciences , 2025, 24 (11), pp.1951-1958. ⟨10.1007/s43630-025-00807-7⟩

Article dans une revue hal-05374963v1

Proteome characterization of XPC-deficient melanocytes generated by CRISPR-Cas9 technology reveals alteration in the expression of several hundred proteins

Muriel Cario , Julie Scalia , Walid Mahfouf , Elodie Muzotte , Vincent Michaud et al.

Journal of Dermatological Science, 2024, 114 (2), pp.79-82. ⟨10.1016/j.jdermsci.2024.03.006⟩

Article dans une revue hal-04622420v1

Metabolomics Analysis of Rabbit Plasma after Ocular Exposure to Vapors of Sulfur Mustard

Jihéne Bouhlel , Fanny Caffin , Fanny Gros-Désormeaux , Thierry Douki , Jean-François Benoist et al.

Metabolites, 2024, 14 (7), pp.349. ⟨10.3390/metabo14070349⟩

Article dans une revue hal-04625280v1

Improved photoprotection in the UVA/visible radiation boundary region is essential to prevent DNA damage, oxidative stress and gene expression changes in human skin

Karl P Lawrence , Thierry Douki , Robert P E Sarkany , Stephanie Acker , Bernd Herzog et al.

JEADV Clinical Practice, 2024, 4 (2), pp.440-450. ⟨10.1002/jvc2.586⟩

Article dans une revue hal-04792386v1
Deposit thumbnail

Blue light impairs the repair of UVB-induced pyrimidine dimers in a human skin model

Thierry Douki , Daniel Bacqueville , Carine Jacques , Camille Geniès , Nicolas Roullet et al.

Photochemistry and Photobiology, 2024, pp.1-6. ⟨10.1111/php.13921⟩

Article dans une revue hal-04454953v1

Data processing for predicting DNA damaging properties of complex UV sources

Thierry Douki , Océane Millot , Arnaud Buhot

ChemPhysChem, 2024, ⟨10.1002/cphc.202400549⟩

Article dans une revue hal-04622535v1

Extensive HPLC tandem mass spectrometry characterization of soluble degradation products of biodegradable nanoplastics under environmentally relevant temperature and irradiation conditions

Thierry Douki , Vérane Bard , Maëva Boulée , Marie Carrière

Environmental science‎.Nano, 2024, 11, pp.3956-3965. ⟨10.1039/D3EN00960B⟩

Article dans une revue hal-04666026v1

Selective enhancement of (6–4) photoproduct formation in dithymine dinucleotides driven by specific sugar puckering

Jouda Jakhlal , Clément Denhez , Stéphanie Coantic-Castex , Agathe Martinez , Dominique Harakat et al.

Organic & Biomolecular Chemistry, 2024, 22 (15), pp.3025-3034. ⟨10.1039/d4ob00279b⟩

Article dans une revue hal-04622416v1
Deposit thumbnail

Nuclear and Urinary Measurements Show the Efficacy of Sun-Protection Factor 50+ Sunscreen against DNA Photoproducts upon Real-Life Recreational Exposure

Thierry Douki , Sylvain Caillat , Camille Géniès , Celine Huyghe , Hélène Duplan et al.

JID Innovations, 2023, 3, ⟨10.1016/j.xjidi.2023.100227⟩

Article dans une revue hal-04287281v1
Deposit thumbnail

Identification of 2-Methylthio-methylenethio-N-6-(cis-4-hydroxyisopentenyl)adenosine (msms(2)io(6)A(37)) as a Novel Modification at Adenosine 37 of tRNAs from Salmonella typhimurium

Marouane Libiad , Thierry Douki , Marc Fontecave , Mohamed Atta

ChemBioChem, 2023, 24 (6), pp.e202300019. ⟨10.1002/cbic.202300019⟩

Article dans une revue hal-04136510v1
Deposit thumbnail

DNA photoproducts released by repair in biological fluids as biomarkers of the genotoxicity of UV radiation

Noémie Reynaud , Laura Belz , David Béal , Daniel Bacqueville , Hélène Duplan et al.

Analytical and Bioanalytical Chemistry, 2022, 414, pp.7705-7720. ⟨10.1007/s00216-022-04302-1⟩

Article dans une revue hal-03759123v1
Deposit thumbnail

SN- and NS-puckered sugar conformers are precursors of the (6–4) photoproduct in thymine dinucleotide

Jouda Jakhlal , Clément Denhez , Stéphanie Coantic-Castex , Agathe Martinez , Dominique Harakat et al.

Organic & Biomolecular Chemistry, 2022, 20 (11), pp.2300-2307. ⟨10.1039/d2ob00044j⟩

Article dans une revue hal-03850053v1

Formulation of a new broad‐spectrum UVB + UVA and blue light SPF50 + sunscreen containing Phenylene Bis‐Diphenyltriazine ( TriAsorB ), an innovative sun filter with unique optical properties

D. Bacqueville , C. Jacques-Jamin , P. Lapalud , Thierry Douki , N. Roullet et al.

Journal of the European Academy of Dermatology and Venereology, 2022, 36 (S6), pp.29-37. ⟨10.1111/jdv.18196⟩

Article dans une revue hal-03703545v1

Proteomic Signatures of Microbial Adaptation to the Highest Ultraviolet-Irradiation on Earth: Lessons From a Soil Actinobacterium

Federico Zannier , Luciano Portero , Thierry Douki , Wolfgang Gärtner , María Farías et al.

Frontiers in Microbiology, 2022, 13, ⟨10.3389/fmicb.2022.791714⟩

Article dans une revue hal-03689520v1
Deposit thumbnail

Synergistic or Antagonist Effects of Different UV Ranges Analyzed by the Combination Index: Application to DNA Photoproducts

Thierry Douki , Arnaud Buhot

Photochemistry and Photobiology, 2022, 98 (3), pp.649-661. ⟨10.1111/php.13528⟩

Article dans une revue hal-03356359v2
Deposit thumbnail

Wavelengths and temporal effects on the response of mammalian cells to UV radiation: Limitations of action spectra illustrated by genotoxicity

Thierry Douki

Journal of Photochemistry and Photobiology B: Biology, 2021, pp.112169. ⟨10.1016/j.jphotobiol.2021.112169⟩

Article dans une revue hal-03155695v1
Deposit thumbnail

Evidence for the systemic diffusion of (2-chloroethyl)-ethyl-sulfide, a sulfur mustard analog, and its deleterious effects in brain

Marie Gilardoni , Daniel Léonço , Fanny Caffin , Fanny Gros-Désormeaux , Camille Eldin et al.

Toxicology, 2021, 462, ⟨10.1016/j.tox.2021.152950⟩

Article dans une revue hal-03345961v1
Deposit thumbnail

Glutathione conjugates of the mercapturic acid pathway and guanine adduct as biomarkers of exposure to CEES, a sulfur mustard analog

Marie Roser , David Béal , Camille Eldin , Leslie Gudimard , Fanny Caffin et al.

Analytical and Bioanalytical Chemistry, 2021, 413, pp.1337-1351. ⟨10.1007/s00216-020-03096-4⟩

Article dans une revue hal-03103848v1

Dark cyclobutane pyrimidine dimers are formed in the epidermis of Fitzpatrick skin types I/II and VI in vivo after exposure to solar‐simulated radiation

Damilola Fajuyigbe , Thierry Douki , Arjan Dijk , Robert Sarkany , Antony Young

Pigment Cell & melanoma research, 2021, 34 (3), pp.575-584. ⟨10.1111/pcmr.12956⟩

Article dans une revue hal-03142136v1

Phenylene Bis-Diphenyltriazine (TriAsorB), a new sunfilter protecting the skin against both UVB + UVA and blue light radiations

D. Bacqueville , C. Jacques-Jamin , H. Dromigny , F. Boyer , Y. Brunel et al.

Photochemical & Photobiological Sciences , 2021, ⟨10.1007/s43630-021-00114-x⟩

Article dans une revue hal-03377989v1
Deposit thumbnail

Toxicity to RAW264.7 Macrophages of Silica Nanoparticles and the E551 Food Additive, in Combination with Genotoxic Agents

Fanny Dussert , Pierre-Adrien Arthaud , Marie-Edith Arnal , Bastien Dalzon , Anaëlle Torres et al.

Nanomaterials, 2020, 10 (7), pp.1418. ⟨10.3390/nano10071418⟩

Article dans une revue cea-02907951v1
Deposit thumbnail

Toxicity and DNA repair in normal human keratinocytes co-exposed to benzo[a]pyrene and sunlight

Anne von Koschembahr , Antonia Youssef , David Béal , Leslie Gudimard , Jean-Philippe Giot et al.

Toxicology in Vitro, 2020, 63, pp.104744. ⟨10.1016/j.tiv.2019.104744⟩

Article dans une revue hal-02417289v1
Deposit thumbnail

Comparative study on gene expression profile in rat lung after repeated exposure to diesel and biodiesel exhausts upstream and downstream of a particle filter

Valérie Lecureur , Christelle Monteil , Marie Jaguin , Fabrice Cazier , David Préterre et al.

Environmental Pollution, 2020, 266 (Part 2), pp.115264. ⟨10.1016/j.envpol.2020.115264⟩

Article dans une revue hal-02930031v1
Deposit thumbnail

Oxidative Stress and Genotoxicity in Melanoma Induction: Impact on Repair Rather Than Formation of DNA Damage?

Thierry Douki

Photochemistry and Photobiology, 2020, ⟨10.1111/php.13278⟩

Article dans une revue hal-02565536v1

DNA Damage Kills Bacterial Spores and Cells Exposed to 222-Nanometer UV Radiation

Taylor Willie , Camilleri Emily , Craft D. Levi , Korza George , Granados Maria Rocha et al.

Applied and Environmental Microbiology, 2020, 86 (8), ⟨10.1128/AEM.03039-19⟩

Article dans une revue hal-02565567v1
Deposit thumbnail

Pyrimidine (6‐4) pyrimidone photoproducts in UVA‐irradiated DNA: photosensitization or photoisomerization?

Thierry Douki

ChemPhotoChem, 2020, 4, pp.294-299. ⟨10.1002/cptc.201900280⟩

Article dans une revue hal-02417294v1

Wavelength‐ and Tissue‐dependent Variations in the Mutagenicity of Cyclobutane Pyrimidine Dimers in Mouse Skin

Ikehata Hironobu , Mori Toshio , Kamei Yasuhiro , Thierry Douki , Cadet Jean et al.

Photochemistry and Photobiology, 2020, 96 (1), pp.94-104. ⟨10.1111/php.13159⟩

Article dans une revue hal-02565634v1
Deposit thumbnail

Guanine radicals induced in DNA by low-energy photoionization

Evangelos Balanikas , A. Banyasz , Thierry Douki , Gérard Baldacchino , Dimitra Markovitsi

Accounts of Chemical Research, 2020, 53, pp.1511-1519. ⟨10.1021/acs.accounts.0c00245⟩

Article dans une revue cea-03053823v1

Impairment of Base Excision Repair in Dermal Fibroblasts Isolated From Nevoid Basal Cell Carcinoma Patients

Aurélie Charazac , Nour Fayyad , David Beal , Sandrine Bourgoin-Voillard , Michel Seve et al.

Frontiers in Oncology, 2020, 10, ⟨10.3389/fonc.2020.01551⟩

Article dans une revue hal-03065922v1

Method for the accurate determination of the DNA protection factor of sun protection products

G. Josse , E. Gravier , Thierry Douki

British Journal of Dermatology, 2020, 183 (1), pp.178-179. ⟨10.1111/bjd.18936⟩

Article dans une revue hal-03065908v1

Photoinduced DNA Lesions in Dormant Bacteria: The Peculiar Route Leading to Spore Photoproducts Characterized by Multiscale Molecular Dynamics

Antonio Francés‐monerris , Cécilia Hognon , Thierry Douki , Antonio Monari

Chemistry - A European Journal, 2020, 26 (62), pp.14236-14241. ⟨10.1002/chem.202002484⟩

Article dans une revue hal-03065911v1
Deposit thumbnail

Metabolism and genotoxicity of polycyclic aromatic hydrocarbons in human skin explants: mixture effects and modulation by sunlight

Anne von Koschembahr , Antonia Youssef , David Béal , Etienne Bourgart , Alex Rivier et al.

Archives of Toxicology, 2020, 94, pp.495-507. ⟨10.1007/s00204-019-02650-z⟩

Article dans une revue hal-02439056v1
Deposit thumbnail

TiO2 genotoxicity: An update of the results published over the last six years

Marie Carrière , Marie-Edith Arnal , Thierry Douki

Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 2020, 854-855, pp.503198. ⟨10.1016/j.mrgentox.2020.503198⟩

Article dans une revue hal-03111807v1

Seasonal Differences in the UVA/UVB Ratio of Natural Sunlight Influence the Efficiency of the Photoisomerization of (6‐4) Photoproducts into their Dewar Valence Isomers

Kazuki Nishimura , Hironobu Ikehata , Thierry Douki , Jean Cadet , Shigeki Sugiura et al.

Photochemistry and Photobiology, 2020, ⟨10.1111/php.13361⟩

Article dans une revue hal-03065905v1
Deposit thumbnail

Structural, biochemical and functional analyses of tRNA-monooxygenase enzyme MiaE from Pseudomonas putida provide insights into tRNA/MiaE interaction

Philippe Carpentier , Chloé Leprêtre , Christian Basset , Thierry Douki , Stéphane Torelli et al.

Nucleic Acids Research, 2020, 48 (17), pp.9918-9930. ⟨10.1093/nar/gkaa667⟩

Article dans une revue hal-03065929v1
Deposit thumbnail

Les biomarqueurs de l’intoxication par l’ypérite

Christophe Piérard , Nicolas Taudon , François Fenaille , Thierry Douki

L'Actualité Chimique, 2019, 440, pp.19-22

Article dans une revue hal-02565929v1

Influence of exposure dose, complex mixture, and ultraviolet radiation on skin absorption and bioactivation of polycyclic aromatic hydrocarbons ex vivo

Etienne Bourgart , Renaud Persoons , Marie Marques , Alex Rivier , Franck Balducci et al.

Archives of Toxicology, 2019, ⟨10.1007/s00204-019-02504-8⟩

Article dans une revue hal-02180840v1
Deposit thumbnail

Toxicological impact of acute exposure to E171 food additive and TiO2 nanoparticles on a co-culture of Caco-2 and HT29-MTX intestinal cells

Marie Dorier , Céline Tisseyre , Fanny Dussert , David Béal , Marie-Edith Arnal et al.

Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2019, 845, pp.402980. ⟨10.1016/j.mrgentox.2018.11.004⟩

Article dans une revue hal-01978322v1
Deposit thumbnail

6-Formylindolo[3,2-b]carbazole (FICZ) is a Very Minor Photoproduct of Tryptophan at Biologically Relevant Doses of UVB and Simulated Sunlight

Antonia Youssef , Anne von Koschembahr , Sylvain Caillat , Sébastien Corre , Marie-Dominique Galibert et al.

Photochemistry and Photobiology, 2019, 95 (1), pp.237-243. ⟨10.1111/php.12950⟩

Article dans une revue hal-01812515v2
Deposit thumbnail

Radicals Generated in Tetramolecular Guanine Quadruplexes by Photoionization: Spectral and Dynamical Features

Akos Banyasz , Evangelos Balanikas , Lara Martinez-Fernandez , Gérard Baldacchino , Thierry Douki et al.

Journal of Physical Chemistry B, 2019, 123 (23), pp.4950-4957. ⟨10.1021/acs.jpcb.9b02637⟩

Article dans une revue cea-02160879v2

The Photochemistry of Unprotected DNA and DNA inside Bacillus subtilis Spores Exposed to Simulated Martian Surface Conditions of Atmospheric Composition, Temperature, Pressure, and Solar Radiation

Wayne Nicholson , Andrew Schuerger , Thierry Douki

Astrobiology, 2018, 18 (4), pp.393 - 402. ⟨10.1089/ast.2017.1721⟩

Article dans une revue hal-01869570v1

Comparative study of diesel and biodiesel exhausts on lung oxidative stress and genotoxicity in rats

Thierry Douki , Cécile Corbière , D. Preterre , Perrine Martin , V. Lecureur et al.

Environmental Pollution, 2018, 235, pp.514-524. ⟨10.1016/j.envpol.2017.12.077⟩

Article dans une revue hal-01711070v1
Deposit thumbnail

Solar simulated light exposure alters metabolization and genotoxicity induced by benzo[a]pyrene in human skin

Anne von Koschembahr , Antonia Youssef , David Béal , Clément Calissi , Etienne Bourgart et al.

Scientific Reports, 2018, 8 (1), ⟨10.1038/s41598-018-33031-8⟩

Article dans une revue hal-01903708v1
Deposit thumbnail

Energy Metabolism Rewiring Precedes UVB-Induced Primary Skin Tumor Formation

Mohsen Hosseini , Léa Dousset , Walid Mahfouf , Martin Serrano-Sanchez , Isabelle Redonnet-Vernhet et al.

Cell Reports, 2018, 23 (12), pp.3621-3634. ⟨10.1016/j.celrep.2018.05.060⟩

Article dans une revue hal-02421137v1
Deposit thumbnail

Sub-optimal Application of a High SPF Sunscreen Prevents Epider­mal DNA Damage in Vivo

A. Young , J Greenaway , G Harrison , K Lawrence , R Sarkany et al.

Acta Dermato-Venereologica, 2018, ⟨10.2340/00015555-2992⟩

Article dans une revue hal-01869569v1

Quantitative analysis of UV photolesions suggests that cyclobutane pyrimidine dimers produced in mouse skin by UVB are more mutagenic than those produced by UVC

Hironobu Ikehata , Toshio Mori , Thierry Douki , Jean Cadet , Masayuki Yamamoto

Photochemical & Photobiological Sciences , 2018, 17 (4), pp.404 - 413. ⟨10.1039/c7pp00348j⟩

Article dans une revue hal-01869573v1
Deposit thumbnail

The UV/Visible Radiation Boundary Region (385–405 nm) Damages Skin Cells and Induces “dark” Cyclobutane Pyrimidine Dimers in Human Skin in vivo

Karl Lawrence , Thierry Douki , Robert Sarkany , Stephanie Acker , Bernd Herzog et al.

Scientific Reports, 2018, 8 (1), ⟨10.1038/s41598-018-30738-6⟩

Article dans une revue hal-01869698v1
Deposit thumbnail

The use of suction blisters to measure sunscreen protection against UVR- induced DNA damage

Gwendal Josse , Thierry Douki , Jimmy Le Digabel , Eleonore Gravier , Emmanuel Questel

Journal of Photochemistry and Photobiology B: Biology, 2018, 179, pp.1 - 6. ⟨10.1016/j.jphotobiol.2017.12.021⟩

Article dans une revue hal-01860395v1
Deposit thumbnail

Formation of UV-induced DNA damage contributing to skin cancer development

Jean Cadet , Thierry Douki

Photochemical & Photobiological Sciences , 2018, 17, pp.1816-1841. ⟨10.1039/c7pp00395a⟩

Article dans une revue hal-01869675v1

A realistic human skin model to study benzo[a]pyrene cutaneous absorption in order to determine the most relevant biomarker for carcinogenic exposure

Etienne Bourgart , Damien Barbeau , Marie Marques , Anne von Koschembahr , David Béal et al.

Archives of Toxicology, 2018, ⟨10.1007/s00204-018-2329-2⟩

Article dans une revue hal-01903702v1
Deposit thumbnail

Impact of nanoparticles on DNA repair processes: current knowledge and working hypotheses

Marie Carrière , Sylvie Sauvaigo , Thierry Douki , Jean-Luc Ravanat

Mutagenesis, 2017, 32 (1), pp.203 - 213. ⟨10.1093/mutage/gew052⟩

Article dans une revue hal-01450635v1

Absorption of Low-Energy UV Radiation by Human Telomere G-Quadruplexes Generates Long-Lived Guanine Radical Cations

Akos Banyasz , Lara Martinez-Fernandez , Clémence Balty , Marion Perron , Thierry Douki et al.

Journal of the American Chemical Society, 2017, 139 (30), pp.10561 - 10568. ⟨10.1021/jacs.7b05931⟩

Article dans une revue cea-01668999v1

Dewar valence isomers, the third type of environmentally relevant DNA photoproducts induced by solar radiation

Thierry Douki , E. Sage

Photochemical & Photobiological Sciences , 2016, 15 (1), pp.24 - 30. ⟨10.1039/c5pp00382b⟩

Article dans une revue hal-01869681v1

Impact of topical application of sulfur mustard on mice skin and distant organs DNA repair enzyme signature

Sylvie Sauvaigo , Fanny Sarrazy , Mohamed Batal , Sylvain Caillat , Benoit Pitiot et al.

Toxicology Letters, 2016, 241, pp.71 - 81. ⟨10.1016/j.toxlet.2015.11.001⟩

Article dans une revue istex hal-01869584v1

Inhibition of the formation of benzo[a]pyrene adducts to DNA in A549 lung cells exposed to mixtures of polycyclic aromatic hydrocarbons

Camille Genies , Amandine Jullien , Emmanuel Lefebvre , Morgane Revol , Anne Maitre et al.

Toxicology in Vitro, 2016, 35, pp.1 - 10. ⟨10.1016/j.tiv.2016.05.006⟩

Article dans une revue istex hal-01869592v1
Deposit thumbnail

Effect of C5-Methylation of Cytosine on the UV-Induced Reactivity of Duplex DNA: Conformational and Electronic Factors

Akos Banyasz , Luciana Esposito , Thierry Douki , Marion Perron , Clément Lepori et al.

Journal of Physical Chemistry B, 2016, 120, pp.4232−4242. ⟨10.1021/acs.jpcb.6b03340⟩

Article dans une revue cea-01334656v1

Molecular hydrogen attenuates radiation-induced nucleobase damage to DNA ă in aerated aqueous solutions

Mhamad Abou-Hamdan , Bernard Gardette , Jean Cadet , Bouchra Gharib , Max de Reggi et al.

International Journal of Radiation Biology, 2016, 92 (9), pp.536-541. ⟨10.1080/09553002.2016.1206234⟩

Article dans une revue hal-01477824v1
Deposit thumbnail

Oxidative DNA damage and repair in the radioresistant archaeon Thermococcus gammatolerans

Ewa Barbier , Arnaud Lagorce , Amine Hachemi , Murielle Dutertre , Aurore Gorlas et al.

Chemical Research in Toxicology, 2016, 29 (11), pp.1796-1809. ⟨10.1021/acs.chemrestox.6b00128⟩

Article dans une revue hal-01434808v1
Deposit thumbnail

Comparison of the DNA damage response in BEAS-2B and A549 cells exposed to titanium dioxide nanoparticles

Mathilde Biola-Clier , David Béal , Sylvain Caillat , S. Libert , L. Armand et al.

Mutagenesis, 2016, 32, pp.161-172. ⟨10.1093/mutage/gew055⟩

Article dans une revue cea-01424852v1

Direct Oxidative Damage of Naked DNA Generated upon Absorption of UV Radiation by Nucleobases

M. Gomez-Mendoza , A. Banyasz , Thierry Douki , D. Markovitsi , J.-L. Ravanat

Journal of Physical Chemistry Letters, 2016, 7 (19), pp.3945-3948. ⟨10.1021/acs.jpclett.6b01781⟩

Article dans une revue cea-01426181v1

Relative Contributions of UVB and UVA to the Photoconversion of (6-4) Photoproducts into their Dewar Valence Isomers

Thierry Douki

Photochemistry and Photobiology, 2016, 92 (4), pp.587 - 594. ⟨10.1111/php.12605⟩

Article dans une revue istex hal-01869593v1

UV and ionizing radiations induced DNA damage, differences and similarities

Jean-Luc Ravanat , Thierry Douki

Radiation Physics and Chemistry, 2016, 128, pp.92 - 102. ⟨10.1016/j.radphyschem.2016.07.007⟩

Article dans une revue istex hal-01450651v1

Chemiexcitation of melanin derivatives induces DNA photoproducts long after UV exposure

Sanjay Premi , Silvia Wallisch , Camila M. Mano , Adam B. Weiner , Antonella Bacchiocchi et al.

Science, 2015, 347 (6224), pp.842-847. ⟨10.1126/science.1256022⟩

Article dans une revue cea-01735136v1

Combination of Aβ Secretion and Oxidative Stress in an Alzheimer-Like Cell Line Leads to the Over-Expression of the Nucleotide Excision Repair Proteins DDB2 and XPC

Anne Forestier , Thierry Douki , Viviana de Rosa de Rosa , David Béal , Walid Rachidi

International Journal of Molecular Sciences, 2015, 16 (8), pp.17422-17444

Article dans une revue hal-02013110v1

A new hair follicle-derived human epidermal model for the evaluation of sunscreen genoprotection

D. Bacqueville , Thierry Douki , L. Duprat , S. Rebelo-Moreira , B. Guiraud et al.

Journal of Photochemistry and Photobiology B: Biology, 2015, 151, pp.31-38. ⟨10.1016/j.jphotobio1.2015.06.015⟩

Article dans une revue hal-01585690v1

The SPORES experiment of the EXPOSE-R mission: Bacillus subtilis spores in artificial meteorites

Corinna Panitz , Gerda Horneck , Elke Rabbow , Petra Rettberg , Ralf Moeller et al.

International Journal of Astrobiology, 2015, 14 (1), pp.105-114. ⟨10.1017/s1473550414000251⟩

Article dans une revue cea-01734602v1

Time course of skin features and inflammatory biomarkers after liquid sulfur mustard exposure in SKH-1 hairless mice

Stephane Mouret , Julien Wartelle , Mohamed Batal , Sandy Emorine , Marine Bertoni et al.

Toxicology Letters, 2015, 232 (1), pp.68-78. ⟨10.1016/j.toxlet.2014.09.022⟩

Article dans une revue istex cea-01734599v1

N4-Methylation of Cytosine Drastically Favors the Formation of (6-4) Photoproducts in a TCG Context

Thierry Douki , Jarah A. Meador , Izabel Berard , Aude Wack

Photochemistry and Photobiology, 2015, 91 (1), pp.102-108. ⟨10.1111/php.12365⟩

Article dans une revue istex hal-01589780v1

A guanine-ethylthioethyl-glutathione adduct as a major DNA lesion in the skin and in organs of mice exposed to sulfur mustard

Mohamed Batal , Silvestre Rebelo-Moreira , Nadege Hamona , Pierre-Alain Bayle , Stéphane Mouret et al.

Toxicology Letters, 2015, 233 (1), pp.1-7. ⟨10.1016/j.toxlet.2015.01.001⟩

Article dans une revue istex hal-01586121v1

A guanine-ethylthioethyl-glutathione adduct as a major DNA lesion in the skin and in organs of mice exposed to sulfur mustard

Mohamed Batal , Silvestre Rebelo-Moreira , Nadège Hamon , Pierre-Alain Bayle , Stéphane Mouret et al.

Toxicology Letters, 2015, 233 (1), pp.1-7. ⟨10.1016/j.toxlet.2015.01.001⟩

Article dans une revue istex hal-04541188v1

Oxidatively Generated Damage to Cellular DNA by UVB and UVA Radiation

Jean Cadet , Thierry Douki , Jean-Luc Ravanat

Photochemistry and Photobiology, 2015, 91 (1), pp.140-155. ⟨10.1111/php.12368⟩

Article dans une revue hal-01587600v1

DNA Photochemistry: Geometrically Unconstrained Pyrimidine (6-4) Pyrimidone Photoproducts Do Photoisomerize

Thierry Douki , Silvestre Rebelo-Moreira , Nadège Hamon , Pierre-Alain Bayle

Organic Letters, 2015, 17 (2), pp.246-249. ⟨10.1021/ol5033267⟩

Article dans une revue hal-01589961v1

Combination of A beta Secretion and Oxidative Stress in an Alzheimer-Like Cell Line Leads to the Over-Expression of the Nucleotide Excision Repair Proteins DDB2 and XPC

Anne Forestier , Thierry Douki , Viviana de Rosa , David Béal , Walid Rachidi

International Journal of Molecular Sciences, 2015, 16 (8), pp.17422-17444. ⟨10.3390/ijms160817422⟩

Article dans une revue hal-01592876v1

Theoretical and experimental study of the fragmentation of protonated uracil

Leila Sadr-Arani , Pierre Mignon , Henry Chermette , Thierry Douki

Chemical Physics Letters, 2014, 605, pp.108-114. ⟨10.1016/j.cplett.2014.05.026⟩

Article dans une revue istex hal-01071776v1

Effect of C5-Methylation of Cytosine on the Photoreactivity of DNA: A Joint Experimental and Computational Study of TCG Trinucleotides

Luciana Esposito , Akos Banyasz , Thierry Douki , Marion Perron , Dimitra Markovitsi et al.

Journal of the American Chemical Society, 2014, 136 (31), pp.10838-10841. ⟨10.1021/ja5040478⟩

Article dans une revue hal-01075288v1

First characterisation of a CPD-class I photolyase from a UV-resistant extremophile isolated from High-Altitude Andean Lakes

Virginia Helena Albarracín , Julian Simon , Gopal Pathak , Lorena Valle , Thierry Douki et al.

Photochemical & Photobiological Sciences , 2014, 13 (5), pp.739 - 750. ⟨10.1039/c3pp50399b⟩

Article dans une revue hal-01869649v1

Contribution of Cytosine-Containing Cyclobutane Dimers to DNA Damage Produced by Photosensitized Triplet-Triplet Energy Transfer

Thierry Douki , Izabel Berard , Aude Wack , Sigrid Andrä

Chemistry - A European Journal, 2014, 20 (19), pp.5787 - 5794. ⟨10.1002/chem.201303905⟩

Article dans une revue istex hal-01869646v1

Radiation-mediated formation of complex damage to DNA: a chemical aspect overview

J.-L. Ravanat , J. Breton , Thierry Douki , D. Gasparutto , A. Grand et al.

British Journal of Radiology, 2014, 87, pp.20130715. ⟨10.1259/bjr.20130715⟩

Article dans une revue hal-00940172v1

Radiation-mediated formation of complex damage to DNA: a chemical aspect overview

J-L Ravanat , J. Breton , Thierry Douki , D. Gasparutto , A. Grand et al.

British Journal of Radiology, 2014, 87 (1035), pp.20130715

Article dans une revue hal-02013115v1

The significance of the Dewar valence photoisomer as a UV radiation-induced DNA photoproduct in marine microbial communities

Jarah Meador , Amy Baldwin , J. Dean Pakulski , Wade Jeffrey , David L. Mitchell et al.

Environmental Microbiology, 2014, 16 (6), pp.1808 - 1820. ⟨10.1111/1462-2920.12414⟩

Article dans une revue istex hal-01869643v1

Evaluation in vitro de la génotoxicité des hydrocarbures aromatiques polycycliques purs ou en mélange

Camille Genies , Anne Maitre , Adeline Tarantini , Thierry Douki

Environnement, Risques & Santé, 2014

Article dans une revue hal-01869687v1

Relative yields of monomeric and dimeric adducts induced by sulphur mustard in isolated and cellular DNA as determined by HPLC/tandem mass spectrometry

M. Batal , I. Boudry , C. Clery-Barraud , S. Mouret , Thierry Douki

Toxicological and Environmental Chemistry, 2013, 95 (2), pp.260-276

Article dans une revue hal-02054526v1
Deposit thumbnail

Combined genotoxic effects of a polycyclic aromatic hydrocarbon (B(a)P) and an heterocyclic amine (PhIP) in relation to colorectal carcinogenesis

Emilien L. Jamin , Anne Riu , Thierry Douki , Laurent Debrauwer , Jean Pierre J. P. Cravedi et al.

PLoS ONE, 2013, 8 (3), pp.11. ⟨10.1371/journal.pone.0058591⟩

Article dans une revue hal-02645457v1
Deposit thumbnail

An abscisic acid-independent oxylipin pathway controls stomatal closure and immune defense in <em>Arabidopsis</em>

Jean-Luc Montillet , Nathalie Leonhardt , Samuel Mondy , Sylvain Tranchimand , Dominique Rumeau et al.

PLoS Biology, 2013, 11 (3), ⟨10.1371/journal.pbio.1001513⟩

Article dans une revue hal-02649868v1

The variety of UV-induced pyrimidine dimeric photoproducts in DNA as shown by chromatographic quantification methods

Thierry Douki

Photochemical & Photobiological Sciences , 2013, 12 (8), pp.1286-1302

Article dans une revue hal-02054558v1

Measurement of oxidatively generated base damage to nucleic acids in cells: facts and artifacts

J. Cadet , Thierry Douki , J. L. Ravanat , J. R. Wagner

Bioanalytical Reviews, 2013, 4, pp.55-74

Article dans une revue hal-02053784v1
Deposit thumbnail

The Extreme Variety of Genotoxic Response to Benzo[a]pyrene in Three Different Human Cell Lines from Three Different Organs

Camille Genies , Anne Maitre , Emmanuel Lefèbvre , Amandine Jullien , Marianne Chopard-Lallier et al.

PLoS ONE, 2013, 8 (11), ⟨10.1371/journal.pone.0078356⟩

Article dans une revue hal-01903135v1
Deposit thumbnail

UV-induced formation of the thymine-thymine pyrimidine (6-4) pyrimidone photoproduct - a DFT study of the oxetane intermediate ring opening

Vanessa Labet , Nelly Lidia Jorge , Christophe Morell , Thierry Douki , Jean Cadet et al.

Photochemical & Photobiological Sciences , 2013, pp.1-8. ⟨10.1039/C3PP50069A⟩

Article dans une revue hal-00842451v1

Temporal and spatial features of the formation of DNA adducts in sulfur mustard-exposed skin

M. Batal , I. Boudry , S. Mouret , J. Wartelle , S. Emorine et al.

Toxicology and applied pharmacology, 2013, 273 (3), pp.644-650

Article dans une revue hal-02054527v1

Melanoma induction by ultraviolet A but not ultraviolet B radiation requires melanin pigment

F. P. Noonan , M. R. Zaidi , A. Wolnicka-Glubisz , M. R. Anver , J. Bahn et al.

Nature Communications, 2012, 3, pp.884. ⟨10.1038/ncomms1893⟩

Article dans une revue hal-02054603v1
Deposit thumbnail

Glutathione depletion and carbon ion radiation potentiate clustered DNA lesions, cell death and prevent chromosomal changes in cancer cells progeny.

Maïté Hanot , Anthony Boivin , Céline Malésys , M. Beuve , A. Colliaux et al.

PLoS ONE, 2012, 7 (11), pp.e44367. ⟨10.1371/journal.pone.0044367⟩

Article dans une revue hal-00788074v1

Photoinduced Damage to Cellular DNA: Direct and Photosensitized Reactions

J. Cadet , S. Mouret , J. L. Ravanat , Thierry Douki

Photochemistry and Photobiology, 2012, 88 (5), pp.1048-1065. ⟨10.1111/j.1751-1097.2012.01200.x⟩

Article dans une revue hal-02054538v1

Resistance of Bacterial Endospores to Outer Space for Planetary Protection Purposes-Experiment PROTECT of the EXPOSE-E Mission

G. Horneck , R. Moeller , J. Cadet , Thierry Douki , R. L. Mancinelli et al.

Astrobiology, 2012, 12 (5), pp.445-+. ⟨10.1089/ast.2011.0737⟩

Article dans une revue hal-02054581v1

Electronic Excited States Responsible for Dimer Formation upon UV Absorption Directly by Thymine Strands: Joint Experimental and Theoretical Study

A. Banyasz , Thierry Douki , R. Improta , T. Gustavsson , D. Onidas et al.

Journal of the American Chemical Society, 2012, 134, pp.14834−14845. ⟨10.1021/ja304069f⟩

Article dans une revue hal-00732999v1

Oxidatively Generated DNA Lesions as Potential Biomarkers of In Vivo Oxidative Stress

J. L. Ravanat , J. Cadet , Thierry Douki

Current Molecular Medicine, 2012, 12 (6), pp.655-671

Article dans une revue hal-02054606v1

Electronic Excitation Energy Transfer between Nucleobases of Natural DNA

I. Vayá , T. Gustavsson , Thierry Douki , Y. Berlin , D. Markovitsi

Journal of the American Chemical Society, 2012, 134 (28), pp11366-11368. ⟨10.1021/ja304328g⟩

Article dans une revue hal-00724240v1

Survival of Spores of the UV-Resistant Bacillus subtilis Strain MW01 After Exposure to Low-Earth Orbit and Simulated Martian Conditions: Data from the Space Experiment ADAPT on EXPOSE-E

M. Wassmann , R. Moeller , E. Rabbow , C. Panitz , G. Horneck et al.

Astrobiology, 2012, 12 (5), pp.498

Article dans une revue hal-02054611v1

Comparison of the mechanism of deamination of 5,6-dihydro-5-methylcytosine with other cytosine derivatives

André Grand , Jean Cadet , Leif A. Eriksson , Vanessa Labet , Nelly L. Jorge et al.

Theoretical Chemistry Accounts: Theory, Computation, and Modeling, 2012, 131 (4), pp.11

Article dans une revue hal-02054578v1

The specificity of UVA-induced DNA damage in human melanocytes

S. Mouret , A. Forestier , Thierry Douki

Photochemical & Photobiological Sciences , 2012, 11 (1), pp.155-162

Article dans une revue hal-02054601v1

4-Demethylwyosine synthase from Pyrococcus abyssi is a radical-S-adenosyl-L-methionine enzyme with an additional [4Fe-4S](+2) cluster that interacts with the pyruvate co-substrate.

Phanélie Perche-Letuvée , Velavan Kathirvelu , Gustav Berggren , Martin Clemancey , Jean-Marc Latour et al.

Journal of Biological Chemistry, 2012, 287 (49), pp.41174-85. ⟨10.1074/jbc.M112.405019⟩

Article dans une revue hal-01069788v1
Deposit thumbnail

Alzheimer’s Disease-Associated Neurotoxic Peptide Amyloid-Β Impairs Base Excision Repair in Human Neuroblastoma Cells

Anne Forestier , Thierry Douki , Sylvie Sauvaigo , Viviana de Rosa de Rosa , Christine Demeilliers et al.

International Journal of Molecular Sciences, 2012, 13 (12), pp.14766-14787. ⟨10.3390/ijms131114766⟩

Article dans une revue hal-02184970v1

Low doses of selenium specifically stimulate the repair of oxidative DNA damage in LNCaP prostate cancer cells

V. De Rosa , P. Erkekoglu , A. Forestier , A. Favier , F. Hincal et al.

Free Radical Research, 2012, 46 (2), pp.105-115. ⟨10.3109/10715762.2011.647009⟩

Article dans une revue hal-02054555v1

Cytotoxic and Genotoxic Impact of TiO2 Nanoparticles on A549 Cells

M. L. Jugan , S. Barillet , A. Simon-Deckers , S. Sauvaigo , Thierry Douki et al.

Journal of Biomedical Nanotechnology, 2011, 7 (1), pp.22-23. ⟨10.1166/jbn.2011.1181⟩

Article dans une revue hal-02054583v1

Individual Photosensitivity of Human Skin and UVA-Induced Pyrimidine Dimers in DNA

J. L. Bourrain , Thierry Douki , J. C. Beani , S. Mouret , M. T. Leccia

Journal of Investigative Dermatology, 2011, 131 (7), pp.1539-1546. ⟨10.1038/jid.2011.47⟩

Article dans une revue hal-02054602v1

Effects of static magnetic field and cadmium on oxidative stress and DNA damage in rat cortex brain and hippocampus

S. Amara , Thierry Douki , C. Garrel , A. Favier , K. Ben Rhouma et al.

Toxicology and Industrial Health, 2011, 27 (2), pp.99-106

Article dans une revue hal-02054523v1

Assessment of the Photoprotection Properties of Sunscreens by Chromatographic Measurement of DNA Damage in Skin Explants

S. Mouret , P. Bogdanowicz , M. J. Haure , N. Castex-Rizzi , J. Cadet et al.

Photochemistry and Photobiology, 2011, 87 (1), pp.109-116

Article dans une revue hal-02054599v1

The toxicity redox mechanisms of cadmium alone or together with copper and zinc homeostasis alteration: its redox biomarkers.

Yves Nzengue , Serge M. Candéias , Sylvie Sauvaigo , Thierry Douki , Alain Favier et al.

Journal of Trace Elements in Medicine and Biology, 2011, 25 (3), pp.171-80. ⟨10.1016/j.jtemb.2011.06.002⟩

Article dans une revue istex hal-01070481v1

Energy Dependence of Gold Nanoparticle Radiosensitization in Plasmid DNA

S. J. Mcmahon , W. B. Hyland , E. Brun , K. T. Butterworth , J. A. Coulter et al.

Journal of Physical Chemistry C, 2011, 115 (41), pp.20160-20167

Article dans une revue hal-02054590v1

Polycyclic aromatic hydrocarbons in binary mixtures modulate the efficiency of benzo[a]pyrene to form DNA adducts in human cells

Adeline Tarantini , Anne Maitre , Emmanuel Lefèbvre , Marie Marques , Afef Rajhi et al.

Toxicology, 2011, 279 (1-3), pp.36 - 44. ⟨10.1016/j.tox.2010.09.002⟩

Article dans une revue istex hal-01903180v1

Survival of thermophilic and hyperthermophilic microorganisms after exposure to UV-C, ionizing radiation and desiccation

K. Beblo , Thierry Douki , G. Schmalz , R. Rachel , R. Wirth et al.

Archives of Microbiology, 2011, 193 (11), pp.797-809

Article dans une revue hal-02054528v1

TOX4 and its binding partners recognize DNA adducts generated by platinum anticancer drugs

Christophe Bounaix Morand Du Puch , Ewa Barbier , Alexandra Kraut , Yohann Couté , Julia Fuchs et al.

Archives of Biochemistry and Biophysics, 2011, 507 (2), pp.296-303

Article dans une revue hal-01985110v1

Oxidatively Generated Damage to DNA by UVA Radiation in Cells and Human Skin

J. Cadet , Thierry Douki

Journal of Investigative Dermatology, 2011, 131 (5), pp.1005-1007. ⟨10.1038/jid.2011.51⟩

Article dans une revue hal-02054530v1

Effect of the chemical composition of organic extracts from environmental and industrial atmospheric samples on the genotoxicity of polycyclic aromatic hydrocarbons mixtures

Adeline Tarantini , Thierry Douki , Marie-Blanche Personnaz , Jean-Luc Besombes , Jean-Luc Jafrezzo et al.

Toxicological and Environmental Chemistry, 2011, 93 (5), pp.941-954. ⟨10.1080/02772248.2011.573621⟩

Article dans une revue insu-00647632v1
Deposit thumbnail

Base Pairing Enhances Fluorescence and Favors Cyclobutane Dimer Formation Induced upon Absorption of UVA Radiation by DNA

A. Bányász , I. Vaya , P. Changenet-Barret , T. Gustavsson , Thierry Douki et al.

Journal of the American Chemical Society, 2011, 133, pp.5163-5165. ⟨10.1021/ja110879m⟩

Article dans une revue hal-00591797v1

Measurement of oxidatively generated base damage in cellular DNA

J. Cadet , Thierry Douki , J. L. Ravanat

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 2011, 711 (1-2), pp.3-12

Article dans une revue hal-02054536v1

Titanium dioxide nanoparticles exhibit genotoxicity and impair DNA repair activity in A549 cells

M.-L. Jugan , S. Barillet , A. Simon-Deckers , Nathalie Herlin-Boime , S. Sauvaigo et al.

Nanotoxicology, 2011, pp.1-13. ⟨10.3109/17435390.2011.587903⟩

Article dans une revue hal-00659337v1

UV photoreactions of the extremely haloalkaliphilic euryarchaeon Natronomonas pharaonis

R. Moeller , G. Reitz , Thierry Douki , J. Cadet , G. Horneck et al.

FEMS Microbiology Ecology, 2010, 73 (2), pp.271-277. ⟨10.1111/j.1574-6941.2010.00893.x⟩

Article dans une revue hal-02054595v1

UV-Induced TA Photoproducts: Formation and Hydrolysis in Double-Stranded DNA

Saâdia Asgatay , Agathe Martinez , Stéphanie Coantic-Castex , Dominique Harakat , Coralie Philippe et al.

Journal of the American Chemical Society, 2010, 132 (30), pp.10260 - 10261. ⟨10.1021/ja1023173⟩

Article dans une revue hal-01891113v1

Thymine cyclobutane dimers: the most frequent ans persistent DNA lesions in skin exposed to both UVB and UVA.

Thierry Douki

Expert Reviews in Dermatology, 2010, 5, pp.649-657

Article dans une revue hal-02053786v1

Genomic bipyrimidine nucleotide frequency and microbial reactions to germicidal UV radiation

Ralf Moeller , Thierry Douki , Petra Rettberg , Günther Reitz , Jean Cadet et al.

Archives of Microbiology, 2010, 192 (7), pp.521-529. ⟨10.1007/s00203-010-0579-3⟩

Article dans une revue hal-02054594v1

Hydrolytic Deamination of 5,6-Dihydrocytosine in a Protic Medium: A Theoretical Study

Vanessa Labet , Christophe Morell , Thierry Douki , Jean Cadet , Leif A. Eriksson et al.

Journal of Physical Chemistry A, 2010, 114 (4), pp.1826-1834. ⟨10.1021/jp9049044⟩

Article dans une revue hal-02054584v1
Deposit thumbnail

Fluorescence of Natural DNA: From the Femtosecond to the Nanosecond Time Scales

I. Vaya , T. Gustavsson , F.-A. Miannay , Thierry Douki , D. Markovitsi

Journal of the American Chemical Society, 2010, 132 (34), pp.11834-11835. ⟨10.1021/ja102800r⟩

Article dans une revue hal-00516393v1
Deposit thumbnail

Involvement of mitochondrial ferredoxin and para-aminobenzoic acid in yeast coenzyme Q biosynthesis.

Fabien Pierrel , Olivier Hamelin , Thierry Douki , Sylvie Kieffer-Jaquinod , Ulrich Mühlenhoff et al.

Chem Biol, 2010, 17 (5), pp.449-59. ⟨10.1016/j.chembiol.2010.03.014⟩

Article dans une revue hal-00497916v1

Conformational Control of TT Dimerization in DNA Conjugates. A Molecular Dynamics Study

M. Mccullagh , M. Hariharan , F. D. Lewis , D. Markovitsi , Thierry Douki et al.

Journal of Physical B, 2010, 114 (15), pp.5215-5221. ⟨10.1021/jp100983t⟩

Article dans une revue hal-00480209v1

Influence of growth temperature and starvation state on survival and DNA damage induction in the marine bacterium Sphingopyxis alaskensis exposed to UV radiation

S. Matallana-Surget , Thierry Douki , J. A. Meador , R. Cavicchioli , F. Joux

Journal of Photochemistry and Photobiology B: Biology, 2010, 100 (2), pp.51-56

Article dans une revue hal-02054588v1

Oxidatively generated base damage to cellular DNA

J. Cadet , Thierry Douki , J. L. Ravanat

Free Radical Biology and Medicine, 2010, 49 (1), pp.9-21

Article dans une revue hal-02054535v1

Aberrant repair of etheno-DNA adducts in leukocytes and colon tissue of colon cancer patients

T. Obtulowicz , A. Winczura , E. Speina , M. Swoboda , J. Janik et al.

Free Radical Biology and Medicine, 2010, 49 (6), pp.1064-1071. ⟨10.1016/j.freeradbiomed.2010.06.027⟩

Article dans une revue hal-02054604v1

The Editorial Board of Photochemistry and Photobiology

Jean Cadet , N. Ahmad , Gonzalo Cosa , Michael E. Davies , Frank R de Gruijl et al.

Photochemistry and Photobiology, 2010, 85 (6), pp.1272-1277. ⟨10.1111/j.1751-1097.2009.00649.x⟩

Article dans une revue hal-00575519v1

Post-translational modification of ribosomal proteins: structural and functional characterization of RimO from Thermotoga maritima, a radical S-adenosylmethionine methylthiotransferase.

Simon Arragain , Ricardo Garcia-Serres , Geneviève Blondin , Thierry Douki , Martin Clemancey et al.

Journal of Biological Chemistry, 2010, 285 (8), pp.5792-801. ⟨10.1074/jbc.M109.065516⟩

Article dans une revue hal-01069703v1

Identification of eukaryotic and prokaryotic methylthiotransferase for biosynthesis of 2-methylthio-N6-threonylcarbamoyladenosine in tRNA.

Simon Arragain , Samuel K Handelman , Farhad Forouhar , Fan-Yan Wei , Kazuhito Tomizawa et al.

Journal of Biological Chemistry, 2010, 285 (37), pp.28425-33. ⟨10.1074/jbc.M110.106831⟩

Article dans une revue hal-01073763v1
Deposit thumbnail

UVA-induced cyclobutane pyrimidine dimers in DNA: a direct photochemical mechanism?

S. Mouret , C. Philippe , J. Gracia-Chantegrel , A. Banyasz , S. Karpati et al.

Organic & Biomolecular Chemistry, 2010, 8, pp.1706-1711. ⟨10.1039/b924712b⟩

Article dans une revue hal-00472822v1

Sensitized formation of oxidatively generated damage to cellular DNA by UVA radiation

J. Cadet , Thierry Douki , J. L. Ravanat , P. Di Mascio

Photochemical & Photobiological Sciences , 2009, 8 (7), pp.903-911

Article dans une revue hal-02054537v1

The role of the maturase HydG in [FeFe]-hydrogenase active site synthesis and assembly

Eric Pilet , Yvain Nicolet , Carole Mathevon , Thierry Douki , Juan-Carlos Fontecilla-Camps et al.

FEBS Letters, 2009, 583 (3), pp.506-511

Article dans une revue hal-00371635v1

Changes in antioxidant status and biochemical parameters after orally cadmium administration in females rats

S. Chater , Thierry Douki , A. Favier , M. Sakly , H. Abdelmelek

Acta Biologica Hungarica, 2009, 60 (1), pp.79-88

Article dans une revue hal-02054542v1

Relative contribution of DNA strand breaks and DNA adducts to the genotoxicity of benzo[a]pyrene as a pure compound and in complex mixtures

Adeline Tarantini , Anne Maitre , Emmanuel Lefebvre , Marie Marques , Caroline Marie et al.

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 2009, 671 (1-2), pp.67 - 75. ⟨10.1016/j.mrfmmm.2009.08.014⟩

Article dans une revue istex hal-01903200v1
Deposit thumbnail

UV-Induced Structural Changes of Model DNA Helices Probed by Optical Spectroscopy

A. Bányász , S. Karpati , E. Lazzarotto , D. Markovitsi , Thierry Douki

Journal of Physical Chemistry C, 2009, 113 (27), pp.11747-11750. ⟨10.1021/jp901841s⟩

Article dans une revue hal-00404379v1

DNA damage, repair and photoadaptation in a xiphophorus fish hybrid

D. L. Mitchell , L. Paniker , Thierry Douki

Photochemistry and Photobiology, 2009, 85 (6), pp.1384-1390

Article dans une revue hal-02054592v1

Effects of static magnetic field exposure on antioxidative enzymes activity and DNA in rat brain

S. Amara , Thierry Douki , C. Garel , A. Favier , M. Sakly et al.

General Physiology and Biophysics, 2009, 28 (3), pp.260-265

Article dans une revue hal-02054522v1

Remarkable resistance to UVB of the marine bacterium Photobacterium angustum explained by an unexpected role of photolyase

S. Matallana-Surget , Thierry Douki , R. Cavicchioli , F. Joux

Photochemical & Photobiological Sciences , 2009, 8 (9), pp.1313-1320

Article dans une revue hal-02054587v1

La spectrométrie de masse : un outil remarquanble pour l'étude des dommages de l'ADN

Thierry Douki , J. L. Ravanat , C. Saint-Pierre , D. Gasparutto , A. Favier et al.

Spectra Analyse, 2009, 271, pp.20-25

Article dans une revue hal-02053787v1

La chimie sous rayonnement : des aspects fondamentaux aux applications dans les sciences des matériaux et les sciences de la vie

Jacqueline Belloni , Mehran Mostafavi , Thierry Douki , Mélanie Spotheim-Maurizot

L'Actualité Chimique, 2008, 316, pp.I-XX rubrique LE DOSSIER

Article dans une revue hal-00282552v1

Genotoxicity of combined exposure to polycyclic aromatic hydrocarbons and UVA - A mechanistic study

Thierry Douki , Z. Ksoury , Caroline Marie , A. Favier , J. L. Ravanat et al.

Photochemistry and Photobiology, 2008, 84 (5), pp.1133-1140. ⟨10.1111/j.1751-1097.2008.00361.x⟩

Article dans une revue istex hal-01973135v1

Influence of the metabolic properties of human cells on the kinetic of formation of the major benzo a pyrene DNA adducts

C. Marie , A. Maitre , Thierry Douki , M. Gateau , A. Tarantini et al.

Journal of Applied Toxicology, 2008, 28 (5), pp.579-590

Article dans une revue hal-02054586v1

Effect of the GC content of DNA on the distribution of UVB-induced bipyrimidine photoproducts

S. Matallana-Surget , J. A. Meador , F. Joux , Thierry Douki

Photochemical & Photobiological Sciences , 2008, 7 (7), pp.794-801

Article dans une revue hal-02054589v1

Determination of new types of DNA lesions in human sperm

C. Badouard , Y. Ménézo , G. Panteix , Jean-Luc Ravanat , Thierry Douki et al.

Zygote, 2008, 16 (1), pp.9-13. ⟨10.1017/S0967199407004340⟩

Article dans une revue istex hal-03390435v1

A zinc-resistant human epithelial cell line is impaired in cadmium and manganese import.

Estelle Rousselet , Pierre Richaud , Thierry Douki , Jocelyne Garcia Chantegrel , Alain Favier et al.

Toxicology and Applied Pharmacology, 2008, 230 (3), pp.312-9. ⟨10.1016/j.taap.2008.02.025⟩

Article dans une revue istex hal-00382017v1

DNA repair and free radicals: New insights into the mechanism of spore photoproduct lyase revealed by single amino acid substitution

Alexia Chandor-Proust , Olivier Berteau , Thierry Douki , Didier Gasparutto , Sandrine Ollagnier de Choudens et al.

Journal of Biological Chemistry, 2008, 283, pp.36361-36368

Article dans une revue hal-00374829v1

Differential repair of UVB-induced cyclobutane pyrimidine dimers in cultured human skin cells and whole human skin

S. Mouret , M. Charveron , A. Favier , J. Cadet , Thierry Douki

DNA Repair, 2008, 7 (5), pp.704-712

Article dans une revue hal-02054600v1

Combined NMR and DFT studies for the absolute configuration elucidation of the spore photoproduct, a UV-induced DNA lesion

Claire Mantel , Alexia Chandor , Didier Gasparutto , Thierry Douki , Mohamed Atta et al.

Journal of the American Chemical Society, 2008, 130 (50), pp.16978-84. ⟨10.1021/ja805032r⟩

Article dans une revue istex hal-01073765v1

Inhibition of S-phase progression triggered by UVA-induced ROS does not require a functional DNA damage checkpoint response in mammalian cells

P. M. Girard , M. Pozzebon , F. Delacote , Thierry Douki , V. Smirnova et al.

DNA Repair, 2008, 7 (9), pp.1500-1516. ⟨10.1016/j.dnarep.2008.05.004⟩

Article dans une revue istex hal-01973138v1

Cadmium-induced oxidative stress and DNA damage in kidney of pregnant female rats

S. Chater , Thierry Douki , C. Garrel , A. Favier , M. Sakly et al.

Comptes Rendus. Biologies, 2008, 331 (6), pp.426-432

Article dans une revue hal-02054543v1

Influence of static magnetic field on cadmium toxicity: study of oxidative stress and DNA damage in pregnant rat tissues

S. Chater , Thierry Douki , A. Favier , C. Garrel , M. Sakly et al.

Electromagnetic Biology and Medicine, 2008, 27 (4), pp.393-401

Article dans une revue hal-02054541v1

Selective one-electron oxidation of duplex DNA oligomers: reaction at thymines

A. Ghosh , A. Joy , G. B. Schuster , Thierry Douki , J. Cadet

Organic & Biomolecular Chemistry, 2008, 6 (5), pp.916-928. ⟨10.1039/B717437C⟩

Article dans une revue istex hal-01973137v1

Low glutathione level favors formation of DNA adducts to 4-hydroxy-2(E)-nonenal, a major lipid peroxidation product

O. Falletti , Thierry Douki

Chemical Research in Toxicology, 2008, 21 (11), pp.2097-2105. ⟨10.1021/tx800169a⟩

Article dans une revue istex hal-01973136v1
Deposit thumbnail

Effect of solar ultraviolet radiation on bacterio- and phytoplankton activity in a large coral reef lagoon (southwest New Caledonia)

P. Conan , F. Joux , P Torréton , Mireille Pujo-Pay , Thierry Douki et al.

Aquatic Microbial Ecology, 2008, 52, pp.83-98. ⟨10.3354/ame01204⟩

Article dans une revue hal-02067410v1

Preventive effect of zinc against cadmium-induced oxidative stress in the rat testis

S. Amara , H. Abdelmelek , C. Garrel , P. Guiraud , Thierry Douki et al.

Journal of Reproduction and Development, 2008, 54 (2), pp.129-134

Article dans une revue hal-02054520v1

Oxidatively generated damage to the guanine moiety of DNA: Mechanistic aspects and formation in cells

J. Cadet , Thierry Douki , J. L. Ravanat

Accounts of Chemical Research, 2008, 41 (8), pp.1075-1083

Article dans une revue hal-02054534v1

A microarray to measure repair of damaged plasmids by cell lysates

J. F. Millau , A. L. Raffin , S. Caillat , C. Claudet , G. Arras et al.

Lab on a Chip, 2008, 8 (10), pp.1713-1722

Article dans une revue hal-02054591v1

UV-radiation-induced formation of DNA bipyrimidine photoproducts in Bacillus subtilis endospores and their repair during germination

R. Moeller , Thierry Douki , J. Cadet , E. Stackebrandt , W. L. Nicholson et al.

International Microbiology, 2007, 10 (1), pp.39-46

Article dans une revue hal-02054593v1

Zinc supplementation ameliorates static magnetic field-induced oxidative stress in rat tissues

S. Amara , H. Abdelmelek , C. Garrel , P. Guiraud , Thierry Douki et al.

Environmental Toxicology and Pharmacology, 2007, 23 (2), pp.193-197

Article dans une revue hal-02054519v1

Trapping of 4-hydroxynonenal by glutathione efficiently prevents formation of DNA adducts in human cells

O. Falletti , J. Cadet , A. Favier , Thierry Douki

Free Radical Biology and Medicine, 2007, 42 (8), pp.1258-1269

Article dans une revue hal-02054571v1

Les photodommages d'ADN

D. Markovitsi , Nadia Chouini-Lalanne , P. Clivio , Thierry Douki , J.-L. Ravanat et al.

L'Actualité Chimique, 2007, 308-309, pp.8-14

Article dans une revue hal-00177160v1

Characterization of the DNA repair spore photoproduct lyase enzyme from Clostridium acetobutylicum: A radical-SAM enzyme.

Alexia Chandor , Thierry Douki , Didier Gasparutto , Serge Gambarelli , Yiannis Sanakis et al.

Comptes Rendus. Chimie, 2007, 10, pp.756-765

Article dans une revue hal-00377642v2

Influence of a static magnetic field (250 mT) on the antioxidant response and DNA integrity in THP1 cells

S. Amara , Thierry Douki , J. L. Ravanat , C. Garrel , P. Guiraud et al.

Physics in Medicine and Biology, 2007, 52 (4), pp.889-898

Article dans une revue hal-02054524v1

DNA bipyrimidine photoproduct repair and transcriptional response of UV-C irradiated Bacillus subtilis

R. Moeller , E. Stackebrandt , Thierry Douki , J. Cadet , P. Rettberg et al.

Archives of Microbiology, 2007, 188 (4), pp.421-431

Article dans une revue hal-02054596v1

Cell surface expression of melanocortin-1 receptor on HaCaT keratinocytes and alpha-melanocortin stimulation do not affect the formation and repair of UVB-induced DNA photoproducts

G. Garcin , Thierry Douki , P. E. Stoebner , J. Guesnet , A. Guezennec et al.

Photochemical & Photobiological Sciences , 2007, 6 (5), pp.585-593. ⟨10.1039/B615656H⟩

Article dans une revue istex hal-02054576v1

One-electron oxidation of DNA and inflammation processes

J. Cadet , Thierry Douki , J. L. Ravanat

Nature Chemical Biology, 2006, 2 (7), pp.348-349

Article dans une revue hal-02054533v1

Effect of denaturation on the photochemistry of pyrimidine bases in isolated DNA

Thierry Douki

Journal of Photochemistry and Photobiology B: Biology, 2006, 82 (1), pp.45-52

Article dans une revue hal-02054556v1

Oxidative DNA damage and antioxidant defenses in the European common lizard (Lacerta vivipara) in supercooled and frozen states

Y. Voituron , S. Servais , C. Romestaing , Thierry Douki , H. Barré

cryobiology., 2006, 52, pp.74-82. ⟨10.1016/j.cryobiol.2005.09.006⟩

Article dans une revue istex hal-00091729v1

Dinucleotide spore photoproduct: a minimal substrate of the DNA repair spore photoproduct lyase enzyme from Bacillus subtilis

Alexia Chandor , Olivier Berteau , Thierry Douki , Didier Gasparutto , Yiannis Sanakis et al.

Journal of Biological Chemistry, 2006, pp.26922-26931

Article dans une revue hal-00374602v1

Minor contribution of direct ionization to DNA base damage induced by heavy ions

Thierry Douki , J. L. Ravanat , J. P. Pouget , I. Testard , J. Cadet

International Journal of Radiation Biology, 2006, 82 (2), pp.119-127. ⟨10.1080/09553000600573788⟩

Article dans une revue hal-02054564v1

Age-dependent DNA repair and cell cycle distribution of human skin fibroblasts in response to UVA irradiation

F. Hazane , S. Sauvaigo , Thierry Douki , A. Favier , J. C. Beani

Journal of Photochemistry and Photobiology B: Biology, 2006, 82 (3), pp.214-223

Article dans une revue hal-02054580v1

Adducts of oxylipin electrophiles to glutathione reflect a 13 specificity of the downstream lipoxygenase pathway in the tobacco hypersensitive response

C. Davoine , O. Falletti , Thierry Douki , G. Iacazio , N. Ennar et al.

Plant Physiology, 2006, 140 (4), pp.1484-1493

Article dans une revue hal-02054553v1

Low ionic strength reduces cytosine photoreactivity in UVC-irradiated isolated DNA

Thierry Douki

Photochemical & Photobiological Sciences , 2006, 5 (11), pp.1045-1051

Article dans une revue hal-02054557v1

Exposure to static magnetic field of pregnant rats induces hepatic GSH elevation but not oxidative DNA damage in liver and kidney

S. Chater , H. Abdelmelek , Thierry Douki , C. Garrel , A. Favier et al.

Archives of Medical Research, 2006, 37 (8), pp.941-946

Article dans une revue hal-02054540v1

Influence of static magnetic field on cadmium toxicity: Study of oxidative stress and DNA damage in rat tissues

S. Amara , H. Abdelmelek , C. Garrel , P. Guiraud , Thierry Douki et al.

Journal of Trace Elements in Medicine and Biology, 2006, 20 (4), pp.263-269

Article dans une revue hal-02054518v1
Deposit thumbnail

An aromatic hydroxylation reaction catalyzed by a two-component FMN-dependent Monooxygenase. The ActVA-ActVB system from Streptomyces coelicolor.

Julien Valton , Marc Fontecave , Thierry Douki , Steven G Kendrew , Vincent Nivière

Journal of Biological Chemistry, 2006, 281 (1), pp.27-35. ⟨10.1074/jbc.M506146200⟩

Article dans une revue hal-01075784v1

Soil fungi reduce the iron content and the DNA damaging effects of asbestos fibers

S. Daghino , F. Turci , M. Tomatis , A. Favier , S. Perotto et al.

Environmental Science and Technology, 2006, 40 (18), pp.5793-5798

Article dans une revue hal-02054551v1
Deposit thumbnail

Cyclobutane pyrimidine dimers are predominant DNA lesions in whole human skin exposed to UVA radiation

S. Mouret , C. Baudouin , M. Charveron , A. Favier , J. Cadet et al.

Proceedings of the National Academy of Sciences of the United States of America, 2006, 103 (37), pp.13765-13770

Article dans une revue hal-01966814v1

Ionic liquid droplet as e-microreactor.

Philippe Dubois , Gilles Marchand , Yves Fouillet , Jean Berthier , Thierry Douki et al.

Analytical Chemistry, 2006, 78 (14), pp.4909-17. ⟨10.1021/ac060481q⟩

Article dans une revue istex hal-00097914v1

Effects of subchronic exposure to static magnetic field on testicular function in rats

S. Amara , H. Abdelmelek , C. Garrel , P. Guiraud , Thierry Douki et al.

Archives of Medical Research, 2006, 37 (8), pp.947-952

Article dans une revue hal-02054517v1

Effects of the binding of a/b-type small, acid-soluble spore proteins on the photochemistry of DNA in spores of Bacillus subtilis and in vitro

Thierry Douki , B. Setlow , P. Setlow

Photochemistry and Photobiology, 2005, 81 (1), pp.163-169

Article dans une revue hal-02054567v1
Deposit thumbnail

Establishing the background level of base oxidation in human lymphocyte DNA: results of an interlaboratory validation study

Catherine M Gedik , Andrew Collins , Jacques Dubois , Pierre Duez , Léonard Kouegnigan et al.

FASEB Journal, 2005, 19 (1), pp.82-84. ⟨10.1096/fj.04-1767fje⟩

Article dans une revue hal-02054577v1

Photosensitization of DNA by dipicolinic acid, a major component of spores of Bacillus species

Thierry Douki , B. Setlow , P. Setlow

Photochemical & Photobiological Sciences , 2005, 4 (8), pp.591-597

Article dans une revue hal-02054568v1

Ultraviolet radiation-mediated damage to cellular DNA

J. Cadet , E. Sage , Thierry Douki

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 2005, 571 (1-2), pp.3-17

Article dans une revue hal-02054539v1

Resveratrol enhances UVA-induced DNA damage in HaCat human keratinocytes

M. Seve , F. Chimienti , S. Devargnas , M. Aouffen , Thierry Douki et al.

Medicinal Chemistry, 2005, 1, pp.623-633. ⟨10.2174/157340605774598144⟩

Article dans une revue istex hal-02053791v1

Age-related sensitivity to lung oxidative stress during ozone exposure

S. Servais , A. Boussouar , A. Molnar , Thierry Douki , J.M. Pequignot et al.

Free Radical Research, 2005, 39, pp.305-316. ⟨10.1080/10715760400011098⟩

Article dans une revue hal-00021554v1

Repair of the three main types of bipyrimidine DNA photoproducts in human keratinocytes exposed to UVB and UVA radiations

S. Courdavault , C. Baudouin , M. Charveron , B. Canguilhem , A. Favier et al.

DNA Repair, 2005, 4 (7), pp.836-844

Article dans une revue hal-02054549v1

Radiation-induced damage to cellular DNA: measurement and biological role

J. Cadet , Thierry Douki , D. Gasparutto , J. L. Ravanat

Radiation Physics and Chemistry, 2005, 72 (2-3), pp.293-299

Article dans une revue hal-02054532v1

Enhancement of the in vitro transcription by T7 RNA polymerase of short DNA templates containing oxidative thymine lesions

V. Guerniou , D. Gasparutto , Thierry Douki , J. Cadet , S. Sauvaigo

Comptes Rendus. Biologies, 2005, 328 (9), pp.794-801

Article dans une revue hal-02054579v1

Conjugation of Keto Fatty Acids to Glutathione in Plant Tissues. Characterization and Quantification by HPLC-Tandem Mass Spectrometry

C. Davoine , Thierry Douki , G. Iacazio , Montillet J.-L. , C. Triantaphylides

Analytical Chemistry, 2005, 77 (22), pp.7366-7372

Article dans une revue hal-00021170v1

Sensitivity to polychromatic UV-radiation of strains of Deinococcus radiodurans differing in their DNA repair capacity

U. P. de La Vega , P. Rettberg , Thierry Douki , J. Cadet , G. Horneck

International Journal of Radiation Biology, 2005, 81 (8), pp.601-611

Article dans une revue hal-02054554v1

Radiation-induced DNA damage: formation, measurement, and biological features

J. Cadet , S. Bellon , Thierry Douki , S. Frelon , D. Gasparutto et al.

Journal of Environmental Pathology, Toxicology and Oncology, 2004, 23, pp.33-43

Article dans une revue hal-02053781v1

The upstream oxylipin profile of Arabidopsis thaliana: a tool to scan for oxidative stresses

J. L. Montillet , J. L. Cacas , L. Garnier , M. H. Montane , Thierry Douki et al.

The Plant Journal, 2004, 40 (3), pp.439-451

Article dans une revue hal-02054597v1

Unrepaired cyclobutane pyrimidine dimers do not prevent proliferation of UV-B-irradiated cultured human fibroblasts.

Sophie Courdavault , Caroline Baudouin , Sylvie Sauvaigo , Stephane Mouret , Serge M. Candéias et al.

Photochemistry and Photobiology, 2004, 79 (2), pp.145-51

Article dans une revue hal-01949083v1

Interexperimental and interindividual variations of DNA repair capacities after UV-13 and UV-C irradiations of human keratinocytes and fibroblasts

M. Chazal , E. Roux , C. Alapetite , C. Roulin , E. Moustacchi et al.

Photochemistry and Photobiology, 2004, 79 (3), pp.286-290

Article dans une revue hal-02054544v1

MiaB protein is a bifunctional radical-S-adenosylmethionine enzyme involved in thiolation and methylation of tRNA

F. Pierrel , Thierry Douki , M. Fontecave , M. Atta

Journal of Biological Chemistry, 2004, 279 (46), pp.47555-47563

Article dans une revue hal-02054605v1

Larger yield of cyclobutane dimers than 8-oxo-7,8-dihydroguanine in the DNA of UVA-irradiated human skin cells

S. Courdavault , C. Baudouin , M. Charveron , A. Favier , J. Cadet et al.

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 2004, 556 (1-2), pp.135-142

Article dans une revue hal-02054550v1

Predominance of the 1,N2-propano 2 '-deoxyguanosine adduct among 4-hydroxy-2-nonenal-induced DNA lesions

Thierry Douki , F. Odin , S. Caillat , A. Favier , J. Cadet

Free Radical Biology and Medicine, 2004, 37 (1), pp.62-70

Article dans une revue hal-02054563v1

Measurement of DNA oxidation in human cells by chromatographic and enzymic methods

A. Collins , C. Gedik , N. Vaughan , S. Wood , A. White et al.

Free Radical Biology and Medicine, 2003, 34 (8), pp.1089-1099

Article dans une revue hal-02054546v1

Bipyrimidine photoproducts rather than oxidative lesions are the main type of DNA damage involved in the genotoxic effect of solar UVA radiation

Thierry Douki , A. Reynaud-Angelin , J. Cadet , E. Sage

Biochemistry, 2003, 42 (30), pp.9221-9226

Article dans une revue hal-02054565v1

Inter-strand photoproducts are produced in high yield within A-DNA exposed to UVC radiation

Thierry Douki , G. Laporte , J. Cadet

Nucleic Acids Research, 2003, 31 (12), pp.3134-3142

Article dans une revue hal-02054562v1

Formation of the spore photoproduct and other dimeric lesions between adjacent pyrimidines in UVC-irradiated dry DNA

Thierry Douki , J. Cadet

Photochemical & Photobiological Sciences , 2003, 2 (4), pp.433-436

Article dans une revue hal-02054561v1

Oxidative damage to DNA: formation, measurement and biochemical features

J Cadet , Thierry Douki , Didier Gasparutto , Jean-Luc Ravanat

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 2003, 531 (1-2), pp.5-23. ⟨10.1016/j.mrfmmm.2003.09.001⟩

Article dans une revue istex hal-03390508v1

Hydroxyl radical is not the main reactive species involved in the degradation of DNA bases by copper in the presence of hydrogen peroxide

S. Frelon , Thierry Douki , A. Favier , J. Cadet

Chemical Research in Toxicology, 2003, 16 (2), pp.191-197

Article dans une revue hal-02054575v1

Formation of a methide derivative upon photolysis of thymidine bromohydrins

Thierry Douki , G. Vadesne-Bauer , J. Cadet

Journal of Organic Chemistry, 2003, 68 (2), pp.478-482

Article dans une revue hal-02054570v1

Photochemistry of 2-chloropyrimidine

L. Lindqvist , B. Czochralska , M. P. Fontaine-Aupart , W. Kawczynski , F. Tfibel et al.

Photochemical & Photobiological Sciences , 2002, 1 (8), pp.600-606. ⟨10.1039/b203620g⟩

Article dans une revue istex hal-02054585v1

Radical oxidation of the adenine moiety of nucleoside and DNA: 2-hydroxy-2 '-deoxyadenosine is a minor decomposition product

S. Frelon , Thierry Douki , J. Cadet

Free Radical Research, 2002, 36 (5), pp.499-508

Article dans une revue hal-02054573v1

Cellular background level of 8-oxo-7,8-dihydro-2 '-deoxyguanosine: an isotope based method to evaluate artefactual oxidation of DNA during its extraction and subsequent work-up

J. L. Ravanat , Thierry Douki , P. Duez , E. Gremaud , K. Herbert et al.

Carcinogenesis, 2002, 23 (11), pp.1911-1918

Article dans une revue hal-02054608v1

Formation of 2 '-deoxyuridine hydrates upon exposure of nucleosides to gamma radiation and UVC-irradiation of isolated and cellular DNA

Thierry Douki , G. Vadesne-Bauer , J. Cadet

Photochemical & Photobiological Sciences , 2002, 1 (8), pp.565-569

Article dans une revue hal-02054569v1

Recent aspects of oxidative DNA damage: Guanine lesions, measurement and substrate specificity of DNA repair glycosylases

E. Muller , J. L. Ravanat , S. Sauvaigo , J. Cadet , S. Bellon et al.

Biological Chemistry, 2002, 383 (6), pp.933-943

Article dans une revue hal-02054529v1

Comparative study of base damage induced by gamma radiation and Fenton reaction in isolated DNA

S. Frelon , Thierry Douki , A. Favier , J. Cadet

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 2002, 24, pp.2866-2870

Article dans une revue hal-02054574v1

DNA tandem lesions containing 8-oxo-7,8-dihydroguanine and formamido residues arise from intramolecular addition of thymine peroxyl radical to guanine

Thierry Douki , Jérôme Rivière , J. Cadet

Chemical Research in Toxicology, 2002, 15 (3), pp.445-454

Article dans une revue hal-02054566v1

Comparison of results from different laboratories in measuring 8-oxo-2'-deoxyguanosine in synthetic oligonucleotides

B. Riis , A. Collins , C. Gedik , N. Vaughan , S. Wood et al.

Free Radical Research, 2002, 36 (6), pp.649-59

Article dans une revue hal-02053789v1

Is 5-aminolevulinic acid involved in the hepatocellular carcinogenesis of accute intermittent porphyria?

J. Onuki , P. C. Teixeira , M. H. G. Medeiros , D. Dornemann , Thierry Douki et al.

Cellular and Molecular Biology, 2002, 48, pp.17-26

Article dans une revue hal-02053788v1

Assessment of oxidative base damage to isolated and cellular DNA by HPLC-MS/MS measurement

J. Cadet , Thierry Douki , S. Frelon , S. Sauvaigo , J. P. Pouget et al.

Free Radical Biology and Medicine, 2002, 33 (4), pp.441-449. ⟨10.1016/s0891-5849(02)00820-1⟩

Article dans une revue istex hal-02054531v1

Inter-laboratory validation of procedures for measuring 8-oxo-7,8-dihydroguanine/8-oxo-7,8-dihydro-2 '-deoxyguanosine in DNA

C. Casalini , F. Guglielmi , C. Luceri , H. Kasai , R. Kido et al.

Free Radical Research, 2002, 36 (3), pp.239-245

Article dans une revue hal-02054547v1

Comparative analysis of baseline 8-oxo-7,8-dihydroguanine in mammalian cell DNA, by different methods in different laboratories: an approach to consensus

A. Collins , C. Gedik , N. Vaughan , S. Wood , J. Dubois et al.

Carcinogenesis, 2002, 23 (12), pp.2129-2133

Article dans une revue hal-02054545v1

Les lésions radio-induites de l'ADN

Thierry Douki , D. Gasparutto , J. L. Ravanat , S. Sauvaigo , J. Cadet

Médecine Nucléaire - Imagerie Fonctionnelle et Métabolique, 2002, 26, pp.119-125

Article dans une revue hal-02053783v1

Direct and indirect effects of UV radiation on DNA and its components

J. L. Ravanat , Thierry Douki , J. Cadet

Journal of Photochemistry and Photobiology B: Biology, 2001, 63 (1-3), pp.88-102

Article dans une revue hal-02054607v1

Individual determination of the yield of the main UV-induced dimeric pyrimidine photoproducts in DNA suggests a high mutagenicity of CC photolesions

Thierry Douki , J. Cadet

Biochemistry, 2001, 40 (8), pp.2495-2501

Article dans une revue hal-02054560v1

The role of duck hepatitis B virus and aflatoxin B-1 in the induction of oxidative stress in the liver

L. Barraud , Thierry Douki , S. Guerret , M. Chevallier , C. Jamard et al.

Cancer Detection and Prevention, 2001, 25 (2), pp.192-201

Article dans une revue hal-02054525v1

UV laser photolysis of DNA: Effect of duplex stability on charge-transfer efficiency

Thierry Douki , D. Angelov , J. Cadet

Journal of the American Chemical Society, 2001, 123 (46), pp.11360-11366

Article dans une revue hal-02054559v1

Analysis of fluoroquinolone-mediated photosensitization of 2 '-deoxyguanosine, calf thymus and cellular DNA: Determination of Type-I, Type-II and triplet-triplet energy transfer mechanism contribution

S. Sauvaigo , Thierry Douki , F. Odin , S. Caillat , J. L. Ravanat et al.

Photochemistry and Photobiology, 2001, 73 (3), pp.230-237

Article dans une revue hal-02054609v1

Repair of the main UV-induced thymine dimeric lesions within Arabidopsis thaliana DNA: evidence for the major involvement of photoreactivation pathways

A. L. Dany , Thierry Douki , C. Triantaphylides , J. Cadet

Journal of Photochemistry and Photobiology B: Biology, 2001, 65 (2-3), pp.127-135

Article dans une revue hal-02054552v1

Oxidative base damage to DNA: formation, role of metals and measurement

J. Cadet , M. Berger , A. G. Bourdat , Thierry Douki , V. Duarte et al.

L'Anteneo, 2001, 19, pp.39-41

Article dans une revue hal-02053782v1

Protection against radiation-induced degradation of DNA bases by polyamines

Thierry Douki , Y. Bretonniere , J. Cadet

Radiation Research, 2000, 153 (1), pp.29-35. ⟨10.1667/0033-7587(2000)153[0029:parido]2.0.co;2⟩

Article dans une revue hal-02054393v1

Formation of the main UV-induced thymine dimeric lesions within isolated and cellular DNA as measured by high performance liquid chromatography-tandem mass spectrometry

Thierry Douki , M. Court , S. Sauvaigo , F. Odin , J. Cadet

Journal of Biological Chemistry, 2000, 275 (16), pp.11678-11685

Article dans une revue hal-02054394v1

High-performance liquid chromatography-tandem mass spectrometry measurement of radiation-induced base damage to isolated and cellular DNA

S. Frelon , Thierry Douki , J. L. Ravanat , J. P. Pouget , C. Tornabene et al.

Chemical Research in Toxicology, 2000, 13 (10), pp.1002-1010

Article dans une revue hal-02054395v1

DNA damage induced in cells by gamma and UVA radiation as measured by HPLC/GC-MS and HPLC-EC and comet assay

J. P. Pouget , Thierry Douki , M. J. Richard , J. Cadet

Chemical Research in Toxicology, 2000, 13 (7), pp.541-549

Article dans une revue hal-02054396v1

Comparison of different methods of measuring 8-oxoguanine as a marker of oxidative DNA damage

A. R. Collins , J. Brown , M. Bogdanov , J. Cadet , M. Cooke et al.

Free Radical Research, 2000, 32 (4), pp.333-341

Article dans une revue hal-02054399v1

DNA damage by 5-aminolevulinic and 4,5-dioxovaleric acids in the presence of ferritin

P. Di Mascio , P. C. Teixeira , J. Onuki , M. H. G. Medeiros , D. Dornemann et al.

Archives of Biochemistry and Biophysics, 2000, 373 (2), pp.368-374

Article dans une revue hal-02054392v1

Oxidative damage and induced mutations in M13mp2 phage DNA exposed to N-nitrosopyrrolidine with UVA radiation

S. Arimoto-Kobayashi , N. Anma , Y. Yoshinaga , Thierry Douki , J. Cadet et al.

Mutagenesis, 2000, 15 (6), pp.473-477

Article dans une revue hal-02054389v1

Oxidative DNA damage in human lymphocytes: correlations with plasma levels of alpha-tocopherol and carotenoids

F. Bianchini , S. Elmstahl , C. Martinez-Garcia , A. L. Van Kappel , Thierry Douki et al.

Carcinogenesis, 2000, 21 (2), pp.321-324

Article dans une revue hal-02054383v1

Tandem base lesions are generated by hydroxyl radical within isolated DNA in aerated aqueous solution

A. G. Bourdat , Thierry Douki , S. Frelon , D. Gasparutto , J. Cadet

Journal of the American Chemical Society, 2000, 122 (19), pp.4549-4556

Article dans une revue hal-02054390v1

Singlet oxygen DNA damage products: Formation and measurement

J. Cadet , Thierry Douki , J. P. Pouget , J. L. Ravanat

Singlet Oxygen, UV-A, and Ozone, 2000, 319, pp.143-153

Article dans une revue hal-02054391v1

Hydroxyl radical-induced degradation of 2 '-deoxyguanosine under reducing conditions

Thierry Douki , S. Spinelli , J. L. Ravanat , J. Cadet

Journal of the Chemical Society-Perkin Transactions 2, 1999, 9, pp.1875-1880

Article dans une revue hal-01974397v1

2 '-deoxycytidine glycols, a missing link in the free radical-mediated oxidation of DNA

S. Tremblay , Thierry Douki , J. Cadet , J. R. Wagner

Journal of Biological Chemistry, 1999, 274 (30), pp.20833-20838

Article dans une revue hal-01974405v1

Measurement of DNA base damage in cells exposed to low doses of gamma-radiation: comparison between the HPLC-EC and comet assays

Thierry Douki , M. J. Richard , J. Cadet , J. P. Pouget , J. L. Ravanat

International Journal of Radiation Biology, 1999, 75 (1), pp.51-58

Article dans une revue hal-01974402v1

Modification of DNA bases by photosensitized one-electron oxidation

Thierry Douki , J. Cadet

International Journal of Radiation Biology, 1999, 75 (5), pp.571-581

Article dans une revue hal-01974388v1

Oxidation of guanine in cellular DNA by solar UV radiation: Biological role

Thierry Douki , D. Perdiz , P. Grof , Z. Kuluncsics , E. Moustacchi et al.

Photochemistry and Photobiology, 1999, 70 (2), pp.184-190

Article dans une revue hal-01974396v1

Hydroxyl radicals are involved in the oxidation of isolated and cellular DNA bases by 4-aminolevulinic acid

Thierry Douki , J. Onuki , M. H. G. Medeiros , E. J. H. Bechara , J. Cadet et al.

FEBS Letters, 1998, 428 (1-2), pp.93-96

Article dans une revue hal-01974395v1

A novel vicinal lesion obtained from the oxidative photosensitization of TpdG: Characterization and mechanistic aspects

T. Delatour , Thierry Douki , D. Gasparutto , M. C. Brochier , J. Cadet

Chemical Research in Toxicology, 1998, 11 (9), pp.1005-1013

Article dans une revue hal-01974383v1

Formation of 1,N6-etheno-2 '-deoxyadenosine adducts by trans,trans-2,4-decadienal

V. M. Carvalho , P. Di Mascio , I. P. D. Campos , Thierry Douki , J. Cadet et al.

Chemical Research in Toxicology, 1998, 11 (9), pp.1042-1047

Article dans une revue hal-01974381v1

Isotope dilution high-performance liquid chromatography - electrospray tandem mass spectrometry assay for the measurement of 8-oxo-7,8-dihydro-2 '-deoxyguanosine in biological samples

J. L. Ravanat , B. Duretz , A. Guiller , Thierry Douki , J. Cadet

Journal of Chromatography B - Analytical Technologies in the Biomedical and Life Sciences, 1998, 715 (2), pp.349-356

Article dans une revue hal-01974404v1

DNA alkylation by 4,5-dioxovaleric acid, the final oxidation product of 5-aminolevulinic acid

Thierry Douki , J. Onuki , M. H. G. Medeiros , E. J. H. Bechara , J. Cadet et al.

Chemical Research in Toxicology, 1998, 11 (2), pp.150-157

Article dans une revue hal-01974393v1

Photosensitization of thymine nucleobase by benzophenone through energy transfer, hydrogen abstraction and one-electron oxidation

T. Delatour , Thierry Douki , C. d'Ham , J. Cadet

Journal of Photochemistry and Photobiology B: Biology, 1998, 44 (3), pp.191-198

Article dans une revue hal-01974382v1

Far-UV-induced dimeric photoproducts in short oligonucleotides: Sequence effects

Thierry Douki , T. Zalizniak , J. Cadet

Photochemistry and Photobiology, 1997, 66 (2), pp.171-179

Article dans une revue hal-01974400v1

Measurement of 2,6-diamino-4-hydroxy-5-formamidopyrimidine and 8-oxo-7,8-dihydroguanine in isolated DNA exposed to gamma radiation in aqueous solution

Thierry Douki , R. Martini , J. L. Ravanat , R. J. Turesky , J. Cadet

Carcinogenesis, 1997, 18 (12), pp.2385-2391

Article dans une revue hal-01974392v1

Peroxynitrite mediated oxidation of purine bases of nucleosides and isolated DNA

Thierry Douki , J. Cadet

Free Radical Research, 1996, 24 (5), pp.369-380

Article dans une revue hal-01974387v1

Observation and prevention of an artefactual formation of oxidized DNA bases and nucleosides in the GC-EIMS method

Thierry Douki , T. Delatour , F. Bianchini , J. Cadet

Carcinogenesis, 1996, 17 (2), pp.347-353

Article dans une revue hal-01974390v1

Measurement of oxidative damage at pyrimidine bases in gamma-irradiated DNA

Thierry Douki , T. Delatour , F. Paganon , J. Cadet

Chemical Research in Toxicology, 1996, 9 (7), pp.1145-1151

Article dans une revue hal-01974391v1

An adduct between peroxynitrite and 2'-deoxyguanosine: 4,5-dihydro-5-hydroxy-4-(nitrosooxy)-2'-deoxyguanosine

Thierry Douki , J. Cadet , B. N. Ames

Chemical Research in Toxicology, 1996, 9 (1), pp.3-7

Article dans une revue hal-01974389v1

5-hydroxymethyluracil excretion, plasma Tbars and plasma antioxidant vitamins in adriamycin-treated patients

H. Faure , C. Coudray , M. Mousseau , V. Ducros , Thierry Douki et al.

Free Radical Biology and Medicine, 1996, 20 (7), pp.979-983

Article dans une revue hal-01974401v1

Measurement of pyrimidine(6-4) photoproducts in DNA by a mild acidic hydrolysis hplc fluorescence detection assay

Thierry Douki , L. Voituriez , J. Cadet

Chemical Research in Toxicology, 1995, 8 (2), pp.244-253

Article dans une revue hal-01974399v1

Fluorescence quantum yield determination of pyrimidine(6-4) pyrimidone photoadducts

J. Blais , Thierry Douki , P. Vigny , J. Cadet

Photochemistry and Photobiology, 1994, 59 (4), pp.402-404

Article dans une revue hal-01974380v1

Formation of cyclobutane dimers and (6-4)-photoproducts upon far-UV photolysis of 5-methylcytosine-containing dinucleoside monophosphates

Thierry Douki , J. Cadet

Biochemistry, 1994, 33 (39), pp.11942-11950

Article dans une revue hal-01974386v1

An HPLC-EC assay for 1,N2-propano adducts of 2'-deoxyguanosine with 4-hydroxynonenal and other alpha,beta-unsaturated aldehydes

Thierry Douki , B. N. Ames

Chemical Research in Toxicology, 1994, 7 (4), pp.511-518

Article dans une revue hal-01974384v1

HPLC separations of normal and modified nucleobases and nucleosides on an amino silica-gel column

J. L. Ravanat , Thierry Douki , M. F. Incardona , J. Cadet

JOURNAL OF LIQUID CHROMATOGRAPHY, 1993, 16 (15), pp.3185-3202

Article dans une revue hal-01974403v1

Far-UV photochemistry and photosensitization of 2'-deoxycytidylyl-(3'-5')-thymidine - Isolation and characterization of the main photoproducts

Thierry Douki , J. Cadet

Journal of Photochemistry and Photobiology B: Biology, 1992, 15 (3), pp.199-213

Article dans une revue hal-01974385v1

Characterization of the (6-4) photoproduct of 2'-deoxycytidylyl-(3'-5')-thymidine and of its Dewar valence isomer

Thierry Douki , L. Voituriez , J. Cadet

Photochemistry and Photobiology, 1991, 53 (3), pp.293-297

Article dans une revue hal-01974398v1

Genotoxic effects of sunlight in humans: from DNA damage to skin cancer

Thierry Douki

Photobiology School, European Society for Photobiology, Jun 2024, Bressanone, Italy

Communication dans un congrès hal-04625495v1

Impact toxicologique à long terme de pigments de tatouage

Thierry Douki , Lise Aubry

Journées 2024 de la Société Française de Photobiologie, Société Française de Photobiologie, Nov 2024, Paris, France

Communication dans un congrès hal-04773022v1

Evaluer la génotoxicité des UV solaires pour optimiser la photoprotection

Thierry Douki

Webinaire Jeunes Chercheurs, Société Française de Toxicologie Génétique, Apr 2024, en ligne (Webinaire), France

Communication dans un congrès hal-04625466v1

La spectrométrie de masse : un outil pour l’étude de la dégradation des plastiques biodégradables

Thierry Douki

webinaire du réseau thématique de recherche PlastNet, PlastNet, Jun 2024, En ligne, France

Communication dans un congrès hal-04625475v1

Les effets cutanés de la lumière solaire et comment s’en protéger

Thierry Douki

RENCONTRE ANNUELLE ÉDITION 2024, Genespoir, association Française des Albinismes, May 2024, Lyon, France

Communication dans un congrès hal-04625512v1

Toxicity of polycaprolactone and polystyrene nanoparticles, aged in environmental conditions, towards intestinal cells

Maëva Boulée , Thierry Douki , Vérane Bard , Marie Carrière

20th European congress of the European Society of Photobiology, Aug 2023, Lyon, France

Communication dans un congrès hal-04784544v1

Mécanismes génotoxiques induits par les UV impliqués dans la survenue du mélanome

Thierry Douki

congrès joint de la Société Française de Photobiologie, du Groupe sur le Cancer Cutané et de la Société Française de Photodermatologie, Société Française de Photobiologie, Groupe sur le Cancer Cutané et Société Française de Photodermatologie, Jun 2023, Rennes, France

Communication dans un congrès hal-04439139v1

DNA photoproducts outside of the nucleus as biomarkers of the genotoxicity of UV radiation

Thierry Douki

20th Congress of the European Society for Photobiology, European Society for Photobiology, Aug 2023, Lyon, France

Communication dans un congrès hal-04355405v1

Toxicological impact of photodegraded organic tattoo pigments on human cultured keratinocytes

Lise Aubry , Lucie Breuillé , Thierry Douki

20th Congress of the European Society for Photobiology, Aug 2023, Lyon (FR), France

Communication dans un congrès hal-04867986v1

Contribution of UVA to the effects of sunbeds

Thierry Douki

20th Congress of the European Society for Photobiology, European Society for Photobiology, Aug 2023, Lyon, France

Communication dans un congrès hal-04355398v1

Toxicity of polycaprolactone and polystyrene nanoparticles, aged in environmental conditions, towards intestinal cells

Maëva Boulée , Thierry Douki , Vérane Bard , Marie Carrière

Nanosafe 2023, Jun 2023, Grenoble, France

Communication dans un congrès hal-04784552v1

Impact of combined exposure to UVB and UVA on the induction and repair of DNA photoproducts

Thierry Douki

Society for Investigative Dermatology (SID) 2022 Annual Meeting, May 2022, On-line, United States

Communication dans un congrès hal-04355369v1

Glutathione conjugates as biomarkers of the systemic diffusion of vesicating agents

Thierry Douki

CBRNE - 5th Research and Innovation Conference, CEA; DGA; Agence d'Innovation de Défense, May 2022, Lille, France

Communication dans un congrès hal-04355314v1

Mécanismes génotoxiques induits par les UV impliqués dans la survenue du mélanome

Thierry Douki

20es JOURNÉES NATIONALES de PHOTODERMATOLOGIE & JOURNÉE d’ACTUALISATION de CANCÉROLOGIE CUTANÉE & JOURNÉE de PHOTOBIOLOGIE, Société Française de Photodermatologie; Société Française de Photobiologie; Groupe de Cancérologie Cutannée, Jun 2022, Rennes, France

Communication dans un congrès hal-04355383v1

Performances et controverses en photoprotection

Thierry Douki

e-congrès Soleil Peau Cancer Cutané, Feb 2022, en ligne, France

Communication dans un congrès hal-03662853v1

Les photoproduits de l’ADN dans les spores bactériennes

Thierry Douki

Colloque Conjoint HappyBio-SFPb-SFPMed, Nov 2021, Toulouse, France

Communication dans un congrès hal-03662829v1

Optimisation de la préparation d’échantillons biologiques par SPE online et orthogonale pour l’évaluation de l’exposition à l’ypérite

Marie Gilardoni , Camille Eldin , David Beal , Thierry Douki

28e congrès annuel de la Société Française de Toxicologie Analytique, Dec 2020, Grenoble, France. pp.S41-S42, ⟨10.1016/j.toxac.2020.09.006⟩

Communication dans un congrès hal-03103638v1

Exposition au soleil et impact biologique

Thierry Douki

Midi Minatec, Feb 2019, Grenoble, France

Communication dans un congrès hal-02567979v1

UV-induced genotoxic pathways leading to melanoma

Thierry Douki

Light & Life, 17th International Congress of Photobiology / 18th Congress of the European Society for Photobiology, Aug 2019, Barcelona, Spain

Communication dans un congrès hal-02567987v1

Non-additive genotoxic effects of polycyclic aromatic hydrocarbons in mixtures in human in vitro models

Thierry Douki

Meeting Eurotoxicology, Jul 2019, Valencia, Spain

Communication dans un congrès hal-02567980v1

Modulation of genotoxic effects of polycyclic aromatic hydrocarbons in human skin upon co-exposure with sunlight

Thierry Douki , Anne Von Koschembahr , David Béal , Marie-Thérèse Leccia , Jean-Phillipe Giot et al.

Meeting Eurotoxicology, Jul 2019, Valencia, Spain

Communication dans un congrès hal-02567984v1

Biological Effects of Ultraviolet Radiation and Opportunities for Sterilization

Thierry Douki

Forum LED Europe, 2019, Lyon, France

Communication dans un congrès hal-02567894v1

Co-exposure to benzo[a]pyrene and simulated sunlight affect both formation of DNA adducts and repair of pyrimidine dimers

Thierry Douki , A. von Koschembahr , A. Youssef , D. Beal

Biennal Meeting of the American Society for Photobiology, 2018, Tampa FL, United States

Communication dans un congrès hal-02567893v1

Realistic Human Skin Model for the Understanding of Polycyclic Aromatic Hydrocarbons Cutaneous Absorption and Metabolism

Etienne Bourgart , Damien Barbeau , Marie Marques , David Béal , Marie-Thérèse Leccia et al.

16th Perspectives in Percutaneous Penetration Conference, Apr 2018, La Grande Motte, France

Communication dans un congrès hal-01904976v1

Contribution of melanin to the specificity of UV-induced DNA damage in melanocytes

Thierry Douki

Congrès de l'European Society for Pigmented Cells Research, European Society for Pigmented Cells Research, Sep 2018, Rennes, France

Communication dans un congrès hal-02567947v1

Human skin model to study the impact of ultraviolet radiation on skin permeation and metabolism of complex mixtures of polycyclic aromatic hydrocarbons.

Etienne Bourgart , Marie Marques , Anne von Koschembahr , David Béal , Renaud Persoons et al.

20th International Congress on In Vitro Toxicology (ESTIV2018), Oct 2018, Berlin, Germany

Communication dans un congrès hal-01904963v1

Sunlight genotoxicity : a challenge to action spectra ?

Thierry Douki

Biennal Meeting of the American Society for Photobiology,, 2018, Tampa FL, United States

Communication dans un congrès hal-02567895v1

The contribution of UVA to the for formation of pyrimidine dimers in DNA

Thierry Douki

15th International Workshop on Radiation Damage to DNA,, 2018, Aussois, France

Communication dans un congrès hal-02567896v1

Solar simulated light exposure alters metabolization and genotoxicity induced by benzo[a]pyrene in human skin explants

Thierry Douki , Anne von Koschembahr , David Béal , M.-T. Leccia , J.-P. Giot et al.

17th Congress of the European Society for Photobiology, European Society for Photobiology, 2017, Pisa, Italy

Communication dans un congrès hal-02567971v1

Solar simulated light exposure alters metabolization and genotoxicity induced by benzo[a]pyrene in human skin explants

Anne von Koschembahr , David Béal , Marie-Thérèse Leccia , Anne Maitre , Thierry Douki

17th Congress of the European Society for Photobiology, Sep 2017, Pise, Italy

Communication dans un congrès hal-01904829v1

DNA damage included by mixtures of genotoxic agents

Thierry Douki

DNA damage and repair : Computations meet experiments,, 2017, Leiden, Netherlands

Communication dans un congrès hal-02567945v1

Combined actions of UVB and UVA on DNA damage and repair

Thierry Douki

2016 Conference of the American Society for Photobiology, American Society for Photobiology, May 2016, Tampa FL, United States

Communication dans un congrès hal-02567934v1

Recent advances in the formation of DNA damage by UV radiation: from test tube experiments to human skin

Thierry Douki , J.-L. Ravanat , M. Gomez Mendoza , A. Bányász , D. Markovitsi et al.

Joint Meeting of the French and Italian Societies for Photobiology and Photochemistry, French and Italian Societies for Photobiology and Photochemistry, Sep 2016, Bari, Italy

Communication dans un congrès hal-02567951v1

Etude des lésions d'oxydation de l'ADN et de leur réparation chez Thermococcus gammatolerans

E Barbier , A Lagorce , A Hachemi , M Dutertre , L Morand et al.

Congrès du GDR Archées, 2016, Grenoble, France

Communication dans un congrès hal-02569154v1

UV-Induced oxidative lesions: involvement of one-electron oxidation reaction

Thierry Douki , J.-L. Ravanat , M Gomez Mandoza , D. Markovitsi

International Workshop on Radiation Damage to DNA, 2016, Melbourne, Australia

Communication dans un congrès hal-02569150v1

Les dimères cyclobutane de pyrimidine : des photoproduits de l'ADN issus de plusieurs mécanismes

Thierry Douki

Rencontre de la Société Française de Photobiologie et du Groupe Français de Photochimie, Société Française de Photobiologie, Groupe Français de Photochimie, Dec 2015, Paris-Cachan, France

Communication dans un congrès hal-02567925v1

Dewar valence isomer, a biologically relevant DNA photoproduct produced by combined exposure to UVB and UVA

Thierry Douki , S. Rebelo , D. Bacqueville , H. Duplan , J. Meador

16th Congress of the European Society for Photobiology, European Society for Photobiology, Sep 2015, Aveiro, Portugal

Communication dans un congrès hal-02567964v1

Impact of TiO2 nanoparticles on DNA repair in pulmonary cells: a mechanistic study

M Biola-Clier , L. Armand , J.-C Gaillard , J. Armengaud , N. Herlin-Boime et al.

Journées de l’Institut des Métaux en Biologie de Grenoble, 2015, Grenoble, France

Communication dans un congrès hal-02569160v1

Non-additive genotoxic effets of mixtures of polycyclic aromatic hydrocarbons applied to human cells

Thierry Douki

44th Annual Meeting of the European Environmental Mutagenesis and Genomics Society, 2015, Prague, Czech Republic

Communication dans un congrès hal-02567917v1

Induction de photoproduits de l’ADN par les UV : données récentes

Thierry Douki

Table ronde sur les UV, Société Française de Radioprotection, 2015, Paris, France

Communication dans un congrès hal-02567939v1

Ecrans solaires et protection de l’ADN

Thierry Douki

Journée "Photoprotection" de la Société Française de Photobiologie, Société Française de Photobiologie, Jun 2015, Paris, France

Communication dans un congrès hal-02567928v1

Mécanismes et impact de nanoparticcules de TiO2 sur la réparation de l'ADN dans des cellules pulmoniares

M. Biola-Clier , L. Armand , N. Herlin-Boime , J. Armengaud , Thierry Douki et al.

Workshop nanoparticules métalliques, biologie, environnement et santé, 2015, Grenoble, France

Communication dans un congrès hal-02569168v1

Impact et mécanismes d'action de nanoparticules de TiO2 sur la réparation de l'ADN dans des cellules pulmoniares

M Biola-Clier , L. Armand , J-C Gaillard , J. Armengaud , S. Sauvaigo et al.

Séminaire scientifique du labex SERENADE, 2014, Aix-en-Provence, France

Communication dans un congrès hal-02569163v1

Impact of the methylation site of cytosine on the formation of bipyrimidine photoproducts

Thierry Douki , Isabelle Bérard , Aude Wack

37th Meeting of the American Society for Photobiology, American Society for Photobiology, Jun 2014, Sab Diego, United States

Communication dans un congrès hal-02567968v1

UVA and UVC induced excited states and damage of DNA

A. Banyasz , I. Vayá , P. Changenet‐barret , T. Gustavsson , Thierry Douki et al.

International Photochemistry Conference, Jul 2013, Leuven, Belgium

Communication dans un congrès hal-00868961v1

Modulation of the genotoxicity of atmospheric PAHs in cultured cells from target organs

Camille Genies , Anne Maitre , Adeline Tarantini , Emmanuel Lefebvre , Marianne Chopard-Lallier et al.

48th Congress of European Societies of Toxicology EUROTOX, Sep 2012, Paris, France

Communication dans un congrès hal-01904853v1

Interference between nanoparticles and metal homeostasis

A.N. Petit , C.-A. Garcia , S. Candéias , A. Casanova , P. Catty et al.

Nanosafe2010: International Conference on Safe Production and Use of Nanomaterials, Nov 2010, Grenoble, France. pp.012035, ⟨10.1088/1742-6596/304/1/012035⟩

Communication dans un congrès hal-00659353v1

Excited states and reactivity of DNA double helices in the UVA spectral domain

D. Markovitsi , A. Banyasz , I. Vayá , P. Changenet-Barret , T. Gustavsson et al.

International Conference on Photochemistry, Aug 2011, Bejing, China

Communication dans un congrès hal-00658883v1

Excitation transfer in natural DNA

I. Vayá , T. Gustavsson , F.-A. Miannay , Thierry Douki , D. Markovitsi

23ème Réunion Biennale de la Société Royale de Chimie, Jul 2011, Valence, Spain

Communication dans un congrès hal-00658928v1
Deposit thumbnail

UV-induced formation of DNA damage in cells and their mutational consequences

Thierry Douki , S Adar

Roberto Improta; Thierry Douki. DNA Photodamage: From Light Absorption to Cellular Responses and Skin Cancer, Royal Society of Chemistry, 2021, Comprehensive Series in Photochemical & Photobiological Sciences, 978-1-83916-196-4. ⟨10.1039/9781839165580-00133⟩

Chapitre d'ouvrage hal-03689535v1
Deposit thumbnail

Photoinduced processes in DNA: basic theoretic and experimental features

Roberto Improta , Thierry Douki

Roberto Improta; Thierry Douki. DNA Photodamage: From Light Absorption to Cellular Responses and Skin Cancer, Royal Society of Chemistry, 2021, 978-1-83916-558-0. ⟨10.1039/9781839165580-00001⟩

Chapitre d'ouvrage hal-03689530v1

Glutathione conjugates as biomarkers of the systemic diffusion of vesicating agents

Thierry Douki , Marie Gilardoni , Clara-Lou Kang , Christophe Pierard , Fanny Caffin et al.

CBRNE Research and Innovation 5th International Conference, May 2020, Lille, France. 2020

Poster de conférence hal-03662418v1

Impact of solar UV radiation on the genotoxicity of polycyclic aromatic hydrocarbon in skin

Thierry Douki , Anne Von Koschembahr , Antonia Youssef , David Béal , Etienne Bourgart et al.

Light & Life, Aug 2019, Barcelona, Spain

Poster de conférence hal-02567993v1

Comparative study of diesel and biodiesel exhausts repeated exposure on lung genotoxicity in rats

Thierry Douki , Cécile Corbière , David Preterre , Perrine Martin , Valérie Lecureur et al.

47th Meeting of the European Environmental Mutagenesis and Genomics Society (EEMGS) - "Genotoxicology and cancer: Science challenges solved by transdisciplinary collaboration", May 2019, Rennes, France

Poster de conférence hal-02470091v1

Theoretical insight into different repair rates of cyclobutane pyrimidine dimers

Chen-Hui Chan , Francois Dehez , Jean-Luc Ravanat , Thierry Douki , Antonio Monari et al.

Fifteenth edition of the international Workshop on Radiation Damage to DNA, May 2018, Aussois, France

Poster de conférence hal-02124572v1

Toxiciy of E171 food additive (TiO2) on in vitro models of intestinal epithelium

M. Dorier , C. Tisseyre , F. Dussert , D. Béal , Thierry Douki et al.

Nanotoxicology 2018,, 2018, Neuss, Germany

Poster de conférence hal-02569198v1

Nanomaterial genotoxicity: The case of silver nanoparticles

L. Bobyk , A. Tarantini , D. Béal , G. Veronesi , Pierre-Henri Jouneau et al.

New tools and approches for nanomaterial safety assessment, 2017, Malaga, France

Poster de conférence hal-02569189v1

Génotoxicité des hydrocarbures aromatiques polycycliques : nature des lésions de l’ADN, rôle du type cellulaire et effets de mélange

Thierry Douki , Camille Genies , Adeline Tarantini , Anne Maitre

Journées de la Société Française de Toxicologie Génétique, 2015, Caen, France

Poster de conférence hal-02567978v1

Les adduits de l’ypérite dans l’ADN de la peau et d’organes internes après une exposition cutanée chez la souris

Thierry Douki , M. Batal , S. Mouret , C. Cléry-Barraud , S. Sauvaigo

Journées de la Société Française de Toxicologie Génétique, 2015, Caen, France

Poster de conférence hal-02567975v1

Synthesis of the spore photoproduct and structural analogs

N. Hamon , D. Gasparutto , Thierry Douki , M. Atta

XXI Round Table on Nucleosides, Nucleotides and Nucleic Acids Chemical Biology of Nucleic acids, 2014, Poznan, Poland

Poster de conférence hal-02569203v1

Impact de nanoparticules de TiO2 sur la réparation de l'ADN dans des cellules pulmonaires

M. Biola-Clier , L. Armand , J.-C. Gaillard , J. Armengaud , N. Herlin-Boime et al.

Colloque SFTG 2014, 2014, Paris, France

Poster de conférence hal-02569178v1

Impact of TiO2 nanoparticles on DNA repair in A549 and BEAS-2B epithelial pulmonary cells

M. Biola-Clier , L. Armand , J.-C. Gaillard , J. Armengaud , N. Herlin-Boime et al.

Nanotox 2014, 2014, Antalya, Turkey

Poster de conférence hal-02569183v1

Mechanisms of TiO2 nanoparticles genotoxicity: impact on DNA repair in, A549 and BEAS-2B Epithelial Pulmonary Cells

M. Biola-Clier , M.-L. Jugan , L. Armand , J-C. Gaillard , J. Armengaud et al.

Nanosafe 2014, 2014, Grenoble, France

Poster de conférence hal-02569186v1

Toxicity of TiO2 nanoparticles upon chronic exposure of pulmonary cells in vitro

L. Armand , M. Biola-Clier , N. Herlin-Boime , T. Rabilloud , Thierry Douki et al.

Séminaire annuel de la société française de toxicologie génétique, 2014, Paris, France

Poster de conférence hal-02569173v1

LC-MS/MS Quantification of DNA Adducts to Study the Genotoxicity of the Food Contaminants PhIP and B[a]P

Emilien L. Jamin , Marc Audebert , Jerome Molina , Thierry Douki , Laurent Debrauwer

59th ASMS Conference on Mass Spectrometry and Allied Topics, Jun 2011, Denver, Colombia. 2011

Poster de conférence hal-02802652v1