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Valerian DORMOY

Dr Dormoy is Associate Professor for the Faculty of Medicine at the University of Reims Champagne-Ardenne (URCA, France) and holds a Research Chair from the French National Institute of Health and Medical Research (Inserm). His interests encompass the mechanisms of airway epithelial cell plasticity in homeostasis and diseases.

Journal articles34 documents

  • Valérian Dormoy, Odile Filhol, Carole Sourbier, Thierry Massfelder. Editorial: in vitro and in vivo non-clinical models of kidney cancers. Frontiers in Oncology, Frontiers, 2022, 12, pp.987682. ⟨10.3389/fonc.2022.987682⟩. ⟨hal-03805045⟩
  • Emilie Luczka-Majérus, Arnaud Bonnomet, Adeline Germain, Nathalie Lalun, Claire Kileztky, et al.. Ciliogenesis is intrinsically altered in COPD small airways. European Respiratory Journal, 2022, pp.2200791. ⟨10.1183/13993003.00791-2022⟩. ⟨hal-03878797⟩
  • Lynda Saber Cherif, Zania Diabasana, Jeanne-Marie Perotin, Julien Ancel, Laure M. G. Petit, et al.. The Nicotinic Receptor Polymorphism rs16969968 Is Associated with Airway Remodeling and Inflammatory Dysregulation in COPD Patients. Cells, MDPI, 2022, 11 (19), pp.2937. ⟨10.3390/cells11192937⟩. ⟨pasteur-03817861⟩
  • Adeline Germain, Jeanne-Marie Perotin, Gonzague Delepine, Myriam Polette, Gaëtan Deslée, et al.. Whole-Exome Sequencing of Bronchial Epithelial Cells Reveals a Genetic Print of Airway Remodelling in COPD. Biomedicines, MDPI, 2022, 10 (7), pp.1714. ⟨10.3390/biomedicines10071714⟩. ⟨hal-03800243⟩
  • Jean Hagenburg, Eric Bertin, Jean-Hugues Salmon, Aurore Thierry, Jeanne-Marie Perotin, et al.. Association between obesity-related dyspnea in daily living, lung function and body composition analyzed by DXA: a prospective study of 130 patients. BMC Pulmonary Medicine, BioMed Central, 2022, 22 (1), pp.103. ⟨10.1186/s12890-022-01884-5⟩. ⟨hal-03646928⟩
  • A. Jacquet, V. Dormoy, M. Lorenzato, Anne Durlach. Preliminary results on a proposed histopathological assessment of predictive factors for basal cell carcinoma recurrence after primary free margin excision. Skin Health and Disease, Wiley, 2022, 2 (2), pp.e88. ⟨10.1002/ski2.88⟩. ⟨hal-03701414⟩
  • Valérian Dormoy, Jeanne-Marie Perotin, Philippe Gosset, Uwe Maskos, Myriam Polette, et al.. Nicotinic receptors as SARS-CoV-2 spike co-receptors?. Medical Hypotheses, Elsevier, 2022, 158, pp.110741. ⟨10.1016/j.mehy.2021.110741⟩. ⟨pasteur-03509149⟩
  • Valérian Dormoy, Stéphanie Pons, Philippe Gosset, Uwe Maskos. Récepteur nicotinique de l’acétylcholine et bronchopneumopathie chronique obstructive. médecine/sciences, EDP Sciences, 2022, 38 (8-9), pp.637-639. ⟨10.1051/medsci/2022092⟩. ⟨hal-03778842⟩
  • Randa Belgacemi, Soula Danopoulos, Gail Deutsch, Ian Glass, Valérian Dormoy, et al.. Hedgehog Signaling Pathway Orchestrates Human Lung Branching Morphogenesis. International Journal of Molecular Sciences, MDPI, 2022, 23 (9), pp.5265. ⟨10.3390/ijms23095265⟩. ⟨hal-03678029⟩
  • Julien Ancel, Randa Belgacemi, Zania Diabasana, Jeanne-Marie Perotin, Arnaud Bonnomet, et al.. Impaired Ciliary Beat Frequency and Ciliogenesis Alteration during Airway Epithelial Cell Differentiation in COPD. Diagnostics, MDPI, 2021, 11 (9), pp.1579. ⟨10.3390/diagnostics11091579⟩. ⟨hal-03367334⟩
  • Anaëlle Muggeo, Jeanne-Marie Perotin, Audrey Brisebarre, Sandra Dury, Valérian Dormoy, et al.. Extended Bacteria Culture-Based Clustering Identifies a Phenotype Associating Increased Cough and Enterobacterales in Stable Chronic Obstructive Pulmonary Disease. Frontiers in Microbiology, Frontiers Media, 2021, 12, ⟨10.3389/fmicb.2021.781797⟩. ⟨hal-03520576⟩
  • Randa Belgacemi, Zania Diabasana, Antony Hoarau, Xavier Dubernard, Jean‐claude Mérol, et al.. Primary ciliogenesis is a crucial step for multiciliated cell determinism in the respiratory epithelium. Journal of Cellular and Molecular Medicine, Wiley Open Access, 2021, ⟨10.1111/jcmm.16729⟩. ⟨hal-03280088⟩
  • Julien Ancel, Jeanne-Marie Perotin, Maxime Dewolf, Claire Launois, Pauline Mulette, et al.. Hypoxia in Lung Cancer Management: A Translational Approach. Cancers, MDPI, 2021, 13 (14), pp.3421. ⟨10.3390/cancers13143421⟩. ⟨hal-03325614⟩
  • Pauline Mulette, Amaury Jacquet, Anne Durlach, Dimitri Papathanassiou, Paul Lalire, et al.. Pulmonary cavitations with increased 18F-FDG uptake revealing a thoracic endometriosis. Medicine, Lippincott, Williams & Wilkins, 2021, 100 (42), pp.e27550. ⟨10.1097/MD.0000000000027550⟩. ⟨hal-03405175⟩
  • Zania Diabasana, Jeanne-Marie Perotin, Randa Belgacemi, Julien Ancel, Pauline Mulette, et al.. Chr15q25 Genetic Variant rs16969968 Alters Cell Differentiation in Respiratory Epithelia. International Journal of Molecular Sciences, MDPI, 2021, 22 (13), pp.6657. ⟨10.3390/ijms22136657⟩. ⟨hal-03278065⟩
  • Jeanne-Marie Perotin, Myriam Polette, Gaëtan Deslée, Valérian Dormoy. CiliOPD: a ciliopathy-associated COPD endotype. Respiratory Research, BioMed Central, 2021, 22 (1), ⟨10.1186/s12931-021-01665-4⟩. ⟨hal-03170356⟩
  • C. Launois, P. Mulette, J. Ancel, S. Dury, J. Hagenburg, et al.. Traitement du reflux gastro-œsophagien (RGO) dans l’asthme. Revue des Maladies Respiratoires, Elsevier Masson, 2021, ⟨10.1016/j.rmr.2021.04.013⟩. ⟨hal-03246303⟩
  • Vincent Wellemans, Hassan Ait Benhassou, Eloise Fuselier, Fabienne Bellesort, Sandra Dury, et al.. Role of CCR3 in respiratory syncytial virus infection of airway epithelial cells. iScience, Elsevier, 2021, 24 (12), pp.103433. ⟨10.1016/j.isci.2021.103433⟩. ⟨hal-03545906⟩
  • Jeanne-Marie Perotin, Maxime Dewolf, Claire Launois, Valérian Dormoy, Gaëtan Deslee. Bronchoscopic management of asthma, COPD and emphysema. European Respiratory Review, European Respiratory Society, 2021, 30 (159), pp.200029. ⟨10.1183/16000617.0029-2020⟩. ⟨hal-03194039⟩
  • Déborah Neyrinck-Leglantier, Julien Lesage, Silvia Blacher, Arnaud Bonnomet, Walter Hunziker, et al.. ZO-1 Intracellular Localization Organizes Immune Response in Non-Small Cell Lung Cancer. Frontiers in Cell and Developmental Biology, Frontiers media, 2021, 9, pp.749364. ⟨10.3389/fcell.2021.749364⟩. ⟨hal-03470162⟩
  • Julie Routhier, Stéphanie Pons, Mohamed Lamine Freidja, Véronique Dalstein, Jérôme Cutrona, et al.. An innate contribution of human nicotinic receptor polymorphisms to COPD-like lesions. Nature Communications, Nature Publishing Group, 2021, 12, pp.6384. ⟨10.1038/s41467-021-26637-6⟩. ⟨pasteur-03414373⟩
  • Randa Belgacemi, Emilie Luczka, Julien Ancel, Zania Diabasana, Jeanne-Marie Perotin, et al.. Airway epithelial cell differentiation relies on deficient Hedgehog signalling in COPD. EBioMedicine, Elsevier, 2020, 51, pp.102572. ⟨10.1016/j.ebiom.2019.11.033⟩. ⟨hal-02431914⟩
  • Julien Ancel, Randa Belgacemi, Jeanne-Marie Perotin, Zania Diabasana, Sandra Dury, et al.. Sonic hedgehog signalling as a potential endobronchial biomarker in COPD. Respiratory Research, BioMed Central, 2020, 21 (1), ⟨10.1186/s12931-020-01478-x⟩. ⟨hal-03038037⟩
  • Zania Diabasana, Jeanne-Marie Perotin, Randa Belgacemi, Julien Ancel, Pauline Mulette, et al.. Nicotinic Receptor Subunits Atlas in the Adult Human Lung. International Journal of Molecular Sciences, MDPI, 2020, 21 (20), pp.7446. ⟨10.3390/ijms21207446⟩. ⟨pasteur-02975996⟩
  • Maryse Fiche, Valentina Scabia, Patrick Aouad, Laura Battista, Assia Treboux, et al.. Intraductal patient‐derived xenografts of estrogen receptor α‐positive (ER+) breast cancer recapitulate the histopathological spectrum and metastatic potential of human lesions. Journal of Pathology, Wiley, 2019, 247 (3), pp.287-292. ⟨10.1002/path.5200⟩. ⟨hal-02431932⟩
  • C. Guguen, C. Launois, V. Dormoy, M. Dewolf, A. Dumazet, et al.. Asthme et obésité : mécanismes et pistes thérapeutiques. Revue des Maladies Respiratoires, Elsevier Masson, 2019, ⟨10.1016/j.rmr.2019.03.015⟩. ⟨hal-02431921⟩
  • Imene Hamaidi, Catherine Coquard, Sabrina Danilin, Valérian Dormoy, Claire Béraud, et al.. The Lim1 oncogene as a new therapeutic target for metastatic human renal cell carcinoma. Oncogene, Nature Publishing Group, 2019, 38 (1), pp.60-72. ⟨10.1038/s41388-018-0413-y⟩. ⟨hal-02431944⟩
  • Jeanne-Marie Perotin, Claire Launois, Maxime Dewolf, Antoine Dumazet, Sandra Dury, et al.. Managing patients with chronic cough: challenges and solutions. Therapeutics and Clinical Risk Management, Dove Medical Press, 2018, Volume 14, pp.1041-1051. ⟨10.2147/TCRM.S136036⟩. ⟨hal-02431951⟩
  • Jeanne-Marie Perotin, Christelle Coraux, Eymeric Lagonotte, Philippe L. Birembaut, Gonzague Delepine, et al.. Alteration of primary cilia in COPD. European Respiratory Journal, European Respiratory Society, 2018, 52 (1), pp.1800122. ⟨10.1183/13993003.00122-2018⟩. ⟨hal-02431953⟩
  • George Sflomos, Valérian Dormoy, Tauno Metsalu, Rachel Jeitziner, Laura Battista, et al.. A Preclinical Model for ERα-Positive Breast Cancer Points to the Epithelial Microenvironment as Determinant of Luminal Phenotype and Hormone Response. Cancer Cell, Elsevier, 2016, 29 (3), pp.407-422. ⟨10.1016/j.ccell.2016.02.002⟩. ⟨hal-02431957⟩
  • Claire Béraud, Valérian Dormoy, Sabrina Danilin, Véronique Lindner, Audrey Béthry, et al.. Targeting FAK scaffold functions inhibits human renal cell carcinoma growth. International Journal of Cancer, Wiley, 2015, 137 (7), pp.1549-1559. ⟨10.1002/ijc.29522⟩. ⟨hal-03013677⟩
  • William H Goodson, Leroy Lowe, David O Carpenter, Michael Gilbertson, Abdul Manaf Ali, et al.. Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead.. Carcinogenesis, Oxford University Press (OUP), 2015, 36 (Suppl 1), pp.S254-96. ⟨10.1093/carcin/bgv039⟩. ⟨pasteur-01352152⟩
  • V. Dormoy, C. Beraud, V. Lindner, C. Coquard, M. Barthelmebs, et al.. Vitamin D3 triggers antitumor activity through targeting hedgehog signaling in human renal cell carcinoma. Carcinogenesis, Oxford University Press (OUP), 2012, 33 (11), pp.2084 - 2093. ⟨10.1093/carcin/bgs255⟩. ⟨hal-01415832⟩
  • Valérian Dormoy, Sabrina Danilin, Véronique Lindner, Lionel Thomas, Sylvie Rothhut, et al.. The sonic hedgehog signaling pathway is reactivated in human renal cell carcinoma and plays orchestral role in tumor growth.. Molecular Cancer, BioMed Central, 2009, 8 (1), pp.123. ⟨10.1186/1476-4598-8-123⟩. ⟨inserm-00663549⟩

Conference papers1 document

  • Z. Diabasana, R. Belgacemi, J. Ancel, J. Routhier, P. Birembaut, et al.. Implication du SNPα5 dans la bronchopneumopathie chronique obstructive. Journées de Recherche Respiratoire (J2R), Oct 2020, Brest, France. pp.576-577, ⟨10.1016/j.rmr.2021.02.017⟩. ⟨hal-03286828⟩

Conference poster1 document

  • Z. Diabasana, R. Belgacemi, J. Routhier, P. Birembaut, U. Maskos, et al.. Implication des récepteurs nicotiniques dans la bronchopneumopathie Chronique Obstructive. Journées de Recherche Respiratoire (J2R), Oct 2020, Brest, France. 38 (6), pp.576, 2021, ⟨10.1016/j.rmr.2021.02.016⟩. ⟨hal-03286866⟩