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valerian dormoy

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Dr Dormoy is Associate Professor for the Faculty of Medicine at the University of Reims Champagne-Ardenne (URCA, France) and holds a Research Chair from the French National Institute of Health and Medical Research (Inserm). His interests encompass the mechanisms of airway epithelial cell plasticity in homeostasis and diseases.


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The Nicotinic Receptor Polymorphism rs16969968 Is Associated with Airway Remodeling and Inflammatory Dysregulation in COPD Patients

Lynda Saber Cherif , Zania Diabasana , Jeanne-Marie Perotin , Julien Ancel , Laure M. G. Petit
Cells, 2022, 11 (19), pp.2937. ⟨10.3390/cells11192937⟩
Journal articles pasteur-03817861v1
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Editorial: in vitro and in vivo non-clinical models of kidney cancers

Valérian Dormoy , Odile Filhol , Carole Sourbier , Thierry Massfelder
Frontiers in Oncology, 2022, 12, pp.987682. ⟨10.3389/fonc.2022.987682⟩
Journal articles hal-03805045v1
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Hedgehog Signaling Pathway Orchestrates Human Lung Branching Morphogenesis

Randa Belgacemi , Soula Danopoulos , Gail Deutsch , Ian Glass , Valérian Dormoy
International Journal of Molecular Sciences, 2022, 23 (9), pp.5265. ⟨10.3390/ijms23095265⟩
Journal articles hal-03678029v1
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Récepteur nicotinique de l’acétylcholine et bronchopneumopathie chronique obstructive

Valérian Dormoy , Stéphanie Pons , Philippe Gosset , Uwe Maskos
Médecine/Sciences, 2022, 38 (8-9), pp.637-639. ⟨10.1051/medsci/2022092⟩
Journal articles hal-03778842v1
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Ciliogenesis is intrinsically altered in COPD small airways

Emilie Luczka-Majérus , Arnaud Bonnomet , Adeline Germain , Nathalie Lalun , Claire Kileztky
European Respiratory Journal, 2022, pp.2200791. ⟨10.1183/13993003.00791-2022⟩
Journal articles hal-03878797v1
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Association between obesity-related dyspnea in daily living, lung function and body composition analyzed by DXA: a prospective study of 130 patients

Jean Hagenburg , Eric Bertin , Jean-Hugues Salmon , Aurore Thierry , Jeanne-Marie Perotin
BMC Pulmonary Medicine, 2022, 22 (1), pp.103. ⟨10.1186/s12890-022-01884-5⟩
Journal articles hal-03646928v1

Nicotinic receptors as SARS-CoV-2 spike co-receptors?

Valérian Dormoy , Jeanne-Marie Perotin , Philippe Gosset , Uwe Maskos , Myriam Polette
Medical Hypotheses, 2022, 158, pp.110741. ⟨10.1016/j.mehy.2021.110741⟩
Journal articles pasteur-03509149v1
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Preliminary results on a proposed histopathological assessment of predictive factors for basal cell carcinoma recurrence after primary free margin excision

A. Jacquet , V. Dormoy , M. Lorenzato , Anne Durlach
Skin Health and Disease, 2022, 2 (2), pp.e88. ⟨10.1002/ski2.88⟩
Journal articles hal-03701414v1
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Whole-Exome Sequencing of Bronchial Epithelial Cells Reveals a Genetic Print of Airway Remodelling in COPD

Adeline Germain , Jeanne-Marie Perotin , Gonzague Delepine , Myriam Polette , Gaëtan Deslée
Biomedicines, 2022, 10 (7), pp.1714. ⟨10.3390/biomedicines10071714⟩
Journal articles hal-03800243v1
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Primary ciliogenesis is a crucial step for multiciliated cell determinism in the respiratory epithelium

Randa Belgacemi , Zania Diabasana , Antony Hoarau , Xavier Dubernard , Jean‐claude Mérol
Journal of Cellular and Molecular Medicine, 2021, ⟨10.1111/jcmm.16729⟩
Journal articles hal-03280088v1
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Chr15q25 Genetic Variant rs16969968 Alters Cell Differentiation in Respiratory Epithelia

Zania Diabasana , Jeanne-Marie Perotin , Randa Belgacemi , Julien Ancel , Pauline Mulette
International Journal of Molecular Sciences, 2021, 22 (13), pp.6657. ⟨10.3390/ijms22136657⟩
Journal articles hal-03278065v1
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Pulmonary cavitations with increased 18F-FDG uptake revealing a thoracic endometriosis

Pauline Mulette , Amaury Jacquet , Anne Durlach , Dimitri Papathanassiou , Paul Lalire
Medicine, 2021, 100 (42), pp.e27550. ⟨10.1097/MD.0000000000027550⟩
Journal articles hal-03405175v1
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Hypoxia in Lung Cancer Management: A Translational Approach

Julien Ancel , Jeanne-Marie Perotin , Maxime Dewolf , Claire Launois , Pauline Mulette
Cancers, 2021, 13 (14), pp.3421. ⟨10.3390/cancers13143421⟩
Journal articles hal-03325614v1
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Role of CCR3 in respiratory syncytial virus infection of airway epithelial cells

Vincent Wellemans , Hassan Ait Benhassou , Eloise Fuselier , Fabienne Bellesort , Sandra Dury
iScience, 2021, 24 (12), pp.103433. ⟨10.1016/j.isci.2021.103433⟩
Journal articles hal-03545906v1
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Traitement du reflux gastro-œsophagien (RGO) dans l’asthme

C. Launois , P. Mulette , J. Ancel , S. Dury , J. Hagenburg
Revue des Maladies Respiratoires, 2021, ⟨10.1016/j.rmr.2021.04.013⟩
Journal articles hal-03246303v1
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An innate contribution of human nicotinic receptor polymorphisms to COPD-like lesions

Julie Routhier , Stéphanie Pons , Mohamed Lamine Freidja , Véronique Dalstein , Jérôme Cutrona
Nature Communications, 2021, 12, pp.6384. ⟨10.1038/s41467-021-26637-6⟩
Journal articles pasteur-03414373v1

Bronchoscopic management of asthma, COPD and emphysema

Jeanne-Marie Perotin , Maxime Dewolf , Claire Launois , Valérian Dormoy , Gaëtan Deslee
European Respiratory Review, 2021, 30 (159), pp.200029. ⟨10.1183/16000617.0029-2020⟩
Journal articles hal-03194039v1
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ZO-1 Intracellular Localization Organizes Immune Response in Non-Small Cell Lung Cancer

Déborah Neyrinck-Leglantier , Julien Lesage , Silvia Blacher , Arnaud Bonnomet , Walter Hunziker
Frontiers in Cell and Developmental Biology, 2021, 9, pp.749364. ⟨10.3389/fcell.2021.749364⟩
Journal articles hal-03470162v1
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Impaired Ciliary Beat Frequency and Ciliogenesis Alteration during Airway Epithelial Cell Differentiation in COPD

Julien Ancel , Randa Belgacemi , Zania Diabasana , Jeanne-Marie Perotin , Arnaud Bonnomet
Diagnostics, 2021, 11 (9), pp.1579. ⟨10.3390/diagnostics11091579⟩
Journal articles hal-03367334v1
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Extended Bacteria Culture-Based Clustering Identifies a Phenotype Associating Increased Cough and Enterobacterales in Stable Chronic Obstructive Pulmonary Disease

Anaëlle Muggeo , Jeanne-Marie Perotin , Audrey Brisebarre , Sandra Dury , Valérian Dormoy
Frontiers in Microbiology, 2021, 12, ⟨10.3389/fmicb.2021.781797⟩
Journal articles hal-03520576v1
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CiliOPD: a ciliopathy-associated COPD endotype

Jeanne-Marie Perotin , Myriam Polette , Gaëtan Deslée , Valérian Dormoy
Respiratory Research, 2021, 22 (1), ⟨10.1186/s12931-021-01665-4⟩
Journal articles hal-03170356v1
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Sonic hedgehog signalling as a potential endobronchial biomarker in COPD

Julien Ancel , Randa Belgacemi , Jeanne-Marie Perotin , Zania Diabasana , Sandra Dury
Respiratory Research, 2020, 21 (1), ⟨10.1186/s12931-020-01478-x⟩
Journal articles hal-03038037v1
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Nicotinic Receptor Subunits Atlas in the Adult Human Lung

Zania Diabasana , Jeanne-Marie Perotin , Randa Belgacemi , Julien Ancel , Pauline Mulette
International Journal of Molecular Sciences, 2020, 21 (20), pp.7446. ⟨10.3390/ijms21207446⟩
Journal articles pasteur-02975996v1
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Airway epithelial cell differentiation relies on deficient Hedgehog signalling in COPD

Randa Belgacemi , Emilie Luczka , Julien Ancel , Zania Diabasana , Jeanne-Marie Perotin
EBioMedicine, 2020, 51, pp.102572. ⟨10.1016/j.ebiom.2019.11.033⟩
Journal articles hal-02431914v1

Asthme et obésité : mécanismes et pistes thérapeutiques

C. Guguen , C. Launois , V. Dormoy , M. Dewolf , A. Dumazet
Revue des Maladies Respiratoires, 2019, ⟨10.1016/j.rmr.2019.03.015⟩
Journal articles hal-02431921v1
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The Lim1 oncogene as a new therapeutic target for metastatic human renal cell carcinoma

Imene Hamaidi , Catherine Coquard , Sabrina Danilin , Valérian Dormoy , Claire Béraud
Oncogene, 2019, 38 (1), pp.60-72. ⟨10.1038/s41388-018-0413-y⟩
Journal articles hal-02431944v1
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Intraductal patient‐derived xenografts of estrogen receptor α‐positive (ER+) breast cancer recapitulate the histopathological spectrum and metastatic potential of human lesions

Maryse Fiche , Valentina Scabia , Patrick Aouad , Laura Battista , Assia Treboux
Journal of Pathology, 2019, 247 (3), pp.287-292. ⟨10.1002/path.5200⟩
Journal articles hal-02431932v1
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Managing patients with chronic cough: challenges and solutions

Jeanne-Marie Perotin , Claire Launois , Maxime Dewolf , Antoine Dumazet , Sandra Dury
Therapeutics and Clinical Risk Management, 2018, Volume 14, pp.1041-1051. ⟨10.2147/TCRM.S136036⟩
Journal articles hal-02431951v1
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Alteration of primary cilia in COPD

Jeanne-Marie Perotin , Christelle Coraux , Eymeric Lagonotte , Philippe L. Birembaut , Gonzague Delepine
European Respiratory Journal, 2018, 52 (1), pp.1800122. ⟨10.1183/13993003.00122-2018⟩
Journal articles hal-02431953v1

A Preclinical Model for ERα-Positive Breast Cancer Points to the Epithelial Microenvironment as Determinant of Luminal Phenotype and Hormone Response

George Sflomos , Valérian Dormoy , Tauno Metsalu , Rachel Jeitziner , Laura Battista
Cancer Cell, 2016, 29 (3), pp.407-422. ⟨10.1016/j.ccell.2016.02.002⟩
Journal articles hal-02431957v1

Targeting FAK scaffold functions inhibits human renal cell carcinoma growth

Claire Béraud , Valérian Dormoy , Sabrina Danilin , Véronique Lindner , Audrey Béthry
International Journal of Cancer, 2015, 137 (7), pp.1549-1559. ⟨10.1002/ijc.29522⟩
Journal articles hal-03013677v1
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Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead.

William H Goodson , Leroy Lowe , David O Carpenter , Michael Gilbertson , Abdul Manaf Ali
Carcinogenesis, 2015, 36 (Suppl 1), pp.S254-96. ⟨10.1093/carcin/bgv039⟩
Journal articles pasteur-01352152v1

Vitamin D3 triggers antitumor activity through targeting hedgehog signaling in human renal cell carcinoma

V. Dormoy , C. Beraud , V. Lindner , C. Coquard , M. Barthelmebs
Carcinogenesis, 2012, 33 (11), pp.2084 - 2093. ⟨10.1093/carcin/bgs255⟩
Journal articles hal-01415832v1
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The sonic hedgehog signaling pathway is reactivated in human renal cell carcinoma and plays orchestral role in tumor growth.

Valérian Dormoy , Sabrina Danilin , Véronique Lindner , Lionel Thomas , Sylvie Rothhut
Molecular Cancer, 2009, 8 (1), pp.123. ⟨10.1186/1476-4598-8-123⟩
Journal articles inserm-00663549v1