valerian dormoy

64
Documents

Présentation

Dr Dormoy is Associate Professor for the Faculty of Medicine at the University of Reims Champagne-Ardenne (URCA, France) and holds a Research Chair from the French National Institute of Health and Medical Research (Inserm). His interests encompass the mechanisms of airway epithelial cell plasticity in homeostasis and diseases.

Publications

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Publications

TSLP and TSLPr Expression and Localization in the Airways of COPD and Non‐COPD Patients

Lynda Saber Cherif , Maëva Devilliers , Jeanne‐Marie Perotin , Julien Ancel , Alexandre Vivien et al.
European Journal of Immunology, 2025, 55 (1), ⟨10.1002/eji.202451480⟩
Article dans une revue hal-04913660 v1

Evaluation of the Smoking Exposure Effects on Carcinogenesis Markers According to the Localization of Melanocytic Lesions

Laurine Batut , Stéphane Sanchez , Nathalie Lalun , Lynda Saber Cherif , Nicole Bouland et al.
Experimental Dermatology, 2025, 34 (5), ⟨10.1111/exd.70111⟩
Article dans une revue hal-05058996 v1
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Glypican-3 is a key tuner of the Hedgehog pathway in COPD

Laure M G Petit , Lynda Saber Cherif , Maëva A Devilliers , Sarah Hatoum , Julien Ancel et al.
Heliyon, 2025, 11 (1), pp.e41564. ⟨10.1016/j.heliyon.2024.e41564⟩
Article dans une revue hal-04930191 v1
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Bronchiectasis in renal transplant patients: a cross-sectional study

Pauline Mulette , Jeanne-Marie Perotin , Anaëlle Muggeo , Thomas Guillard , Audrey Brisebarre et al.
European Journal of Medical Research, 2024, 29 (1), pp.120. ⟨10.1186/s40001-024-01701-1⟩
Article dans une revue hal-04456607 v1
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High Blood Eosinophil Count at Stable State is Not Associated with Airway Microbiota Distinct Profile in COPD

Jeanne-Marie Perotin , Anaëlle Muggeo , Quentin Lecomte-Thenot , Audrey Brisebarre , Sandra Dury et al.
International Journal of Chronic Obstructive Pulmonary Disease, 2024, Volume 19, pp.765-771. ⟨10.2147/COPD.S453526⟩
Article dans une revue hal-04530339 v1
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Airway epithelial cell cilia transcriptomic dysregulation is associated with the inflammatory phenotype in asthma

Maëva Devilliers , Audrey Brisebarre , Laure Petit , Myriam Polette , Gaëtan Deslée et al.
Article dans une revue hal-04470161 v1
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Peribronchial Inflammatory Cell Assessment in <scp>COPD</scp> Lung Tissues

Maëva A Devilliers , Lynda Saber Cherif , Laure M G Petit , Nathalie Lalun , Arnaud Bonnomet et al.
Journal of Cellular and Molecular Medicine, 2024, 28 (22), ⟨10.1111/jcmm.70229⟩
Article dans une revue hal-04818110 v1
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Obesity Impact on Dyspnea in COPD Patients

Alexis Dupuis , Aurore Thierry , Jeanne-Marie Perotin , Julien Ancel , Valérian Dormoy et al.
International Journal of Chronic Obstructive Pulmonary Disease, 2024, 19, pp.1695-1706. ⟨10.2147/COPD.S450366⟩
Article dans une revue hal-04679623 v1
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Current cough and sputum assessed by the cough and sputum assessment-questionnaire (CASA-Q) is associated with quality of life impairment in cystic fibrosis

Lucie Charon , Claire Launois , Jeanne-Marie Perotin , Bruno Ravoninjatovo , Pauline Mulette et al.
BMC Pulmonary Medicine, 2023, 23 (1), pp.457. ⟨10.1186/s12890-023-02701-3⟩
Article dans une revue hal-04313222 v1
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Airway ciliated cells in adult lung homeostasis and COPD

Laure M.G. Petit , Randa Belgacemi , Julien Ancel , Lynda Saber Cherif , Myriam Polette et al.
European Respiratory Review, 2023, 32 (170), pp.230106. ⟨10.1183/16000617.0106-2023⟩
Article dans une revue hal-04339904 v1
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Soluble biomarkers to predict clinical outcomes in non-small cell lung cancer treated by immune checkpoints inhibitors

Julien Ancel , Valérian Dormoy , Béatrice Nawrocki Raby , Véronique Dalstein , Anne Durlach et al.
Frontiers in Immunology, 2023, 14, ⟨10.3389/fimmu.2023.1171649⟩
Article dans une revue (article de synthèse) hal-04179091 v1
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The Nicotinic Receptor Polymorphism rs16969968 Is Associated with Airway Remodeling and Inflammatory Dysregulation in COPD Patients

Lynda Saber Cherif , Zania Diabasana , Jeanne-Marie Perotin , Julien Ancel , Laure M. G. Petit et al.
Cells, 2022, 11 (19), pp.2937. ⟨10.3390/cells11192937⟩
Article dans une revue pasteur-03817861 v1
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Hedgehog Signaling Pathway Orchestrates Human Lung Branching Morphogenesis

Randa Belgacemi , Soula Danopoulos , Gail Deutsch , Ian Glass , Valérian Dormoy et al.
International Journal of Molecular Sciences, 2022, 23 (9), pp.5265. ⟨10.3390/ijms23095265⟩
Article dans une revue hal-03678029 v1
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Récepteur nicotinique de l’acétylcholine et bronchopneumopathie chronique obstructive

Valérian Dormoy , Stéphanie Pons , Philippe Gosset , Uwe Maskos
Médecine/Sciences, 2022, 38 (8-9), pp.637-639. ⟨10.1051/medsci/2022092⟩
Article dans une revue hal-03778842 v1
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Nicotinic receptors as SARS-CoV-2 spike co-receptors?

Valérian Dormoy , Jeanne-Marie Perotin , Philippe Gosset , Uwe Maskos , Myriam Polette et al.
Medical Hypotheses, 2022, 158, pp.110741. ⟨10.1016/j.mehy.2021.110741⟩
Article dans une revue pasteur-03509149 v1
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Ciliogenesis is intrinsically altered in COPD small airways

Emilie Luczka-Majérus , Arnaud Bonnomet , Adeline Germain , Nathalie Lalun , Claire Kileztky et al.
European Respiratory Journal, 2022, pp.2200791. ⟨10.1183/13993003.00791-2022⟩
Article dans une revue hal-03878797 v1
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Association between obesity-related dyspnea in daily living, lung function and body composition analyzed by DXA: a prospective study of 130 patients

Jean Hagenburg , Eric Bertin , Jean-Hugues Salmon , Aurore Thierry , Jeanne-Marie Perotin et al.
BMC Pulmonary Medicine, 2022, 22 (1), pp.103. ⟨10.1186/s12890-022-01884-5⟩
Article dans une revue hal-03646928 v1
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Preliminary results on a proposed histopathological assessment of predictive factors for basal cell carcinoma recurrence after primary free margin excision

A. Jacquet , V. Dormoy , M. Lorenzato , Anne Durlach
Skin Health and Disease, 2022, 2 (2), pp.e88. ⟨10.1002/ski2.88⟩
Article dans une revue hal-03701414 v1
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Editorial: in vitro and in vivo non-clinical models of kidney cancers

Valérian Dormoy , Odile Filhol , Carole Sourbier , Thierry Massfelder
Frontiers in Oncology, 2022, 12, pp.987682. ⟨10.3389/fonc.2022.987682⟩
Article dans une revue hal-03805045 v1
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Tracheobronchopathia osteochondroplastica: clinical, bronchoscopic, and comorbid features in a case series

Antoine Dumazet , Claire Launois , Francois Lebargy , Romain Kessler , Hervé Vallerand et al.
BMC Pulmonary Medicine, 2022, 22 (1), pp.423. ⟨10.1186/s12890-022-02225-2⟩
Article dans une revue hal-03878821 v1
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Whole-Exome Sequencing of Bronchial Epithelial Cells Reveals a Genetic Print of Airway Remodelling in COPD

Adeline Germain , Jeanne-Marie Perotin , Gonzague Delepine , Myriam Polette , Gaëtan Deslée et al.
Biomedicines, 2022, 10 (7), pp.1714. ⟨10.3390/biomedicines10071714⟩
Article dans une revue hal-03800243 v1

Editorial: in vitro and in vivo non-clinical models of kidney cancers

Valérian Dormoy , Odile Filhol , Carole Sourbier , Thierry Massfelder
Frontiers in Oncology, 2022, 12, ⟨10.3389/fonc.2022.987682⟩
Article dans une revue hal-04278910 v1
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Transcriptomic FHITlow/pHER2high signature as a predictive factor of outcome and immunotherapy response in non-small cell lung cancer

Audrey Brisebarre , Julien Ancel , Théophile Ponchel , Emma Loeffler , Adeline Germain et al.
Frontiers in Immunology, 2022, 13, ⟨10.3389/fimmu.2022.1058531⟩
Article dans une revue hal-03921890 v1
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Extended Bacteria Culture-Based Clustering Identifies a Phenotype Associating Increased Cough and Enterobacterales in Stable Chronic Obstructive Pulmonary Disease

Anaëlle Muggeo , Jeanne-Marie Perotin , Audrey Brisebarre , Sandra Dury , Valérian Dormoy et al.
Frontiers in Microbiology, 2021, 12, ⟨10.3389/fmicb.2021.781797⟩
Article dans une revue hal-03520576 v1
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Impaired Ciliary Beat Frequency and Ciliogenesis Alteration during Airway Epithelial Cell Differentiation in COPD

Julien Ancel , Randa Belgacemi , Zania Diabasana , Jeanne-Marie Perotin , Arnaud Bonnomet et al.
Diagnostics, 2021, 11 (9), pp.1579. ⟨10.3390/diagnostics11091579⟩
Article dans une revue hal-03367334 v1
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Primary ciliogenesis is a crucial step for multiciliated cell determinism in the respiratory epithelium

Randa Belgacemi , Zania Diabasana , Antony Hoarau , Xavier Dubernard , Jean‐claude Mérol et al.
Journal of Cellular and Molecular Medicine, 2021, ⟨10.1111/jcmm.16729⟩
Article dans une revue hal-03280088 v1
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Role of CCR3 in respiratory syncytial virus infection of airway epithelial cells

Vincent Wellemans , Hassan Ait Benhassou , Eloise Fuselier , Fabienne Bellesort , Sandra Dury et al.
iScience, 2021, 24 (12), pp.103433. ⟨10.1016/j.isci.2021.103433⟩
Article dans une revue hal-03545906 v1
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Traitement du reflux gastro-œsophagien (RGO) dans l’asthme

C. Launois , P. Mulette , J. Ancel , S. Dury , J. Hagenburg et al.
Revue des Maladies Respiratoires, 2021, ⟨10.1016/j.rmr.2021.04.013⟩
Article dans une revue hal-03246303 v1
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Chr15q25 Genetic Variant rs16969968 Alters Cell Differentiation in Respiratory Epithelia

Zania Diabasana , Jeanne-Marie Perotin , Randa Belgacemi , Julien Ancel , Pauline Mulette et al.
International Journal of Molecular Sciences, 2021, 22 (13), pp.6657. ⟨10.3390/ijms22136657⟩
Article dans une revue hal-03278065 v1
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Pulmonary cavitations with increased 18F-FDG uptake revealing a thoracic endometriosis

Pauline Mulette , Amaury Jacquet , Anne Durlach , Dimitri Papathanassiou , Paul Lalire et al.
Medicine, 2021, 100 (42), pp.e27550. ⟨10.1097/MD.0000000000027550⟩
Article dans une revue hal-03405175 v1
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Hypoxia in Lung Cancer Management: A Translational Approach

Julien Ancel , Jeanne-Marie Perotin , Maxime Dewolf , Claire Launois , Pauline Mulette et al.
Cancers, 2021, 13 (14), pp.3421. ⟨10.3390/cancers13143421⟩
Article dans une revue hal-03325614 v1
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Bronchoscopic management of asthma, COPD and emphysema

Jeanne-Marie Perotin , Maxime Dewolf , Claire Launois , Valérian Dormoy , Gaëtan Deslee
European Respiratory Review, 2021, 30 (159), pp.200029. ⟨10.1183/16000617.0029-2020⟩
Article dans une revue hal-03194039 v1
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CiliOPD: a ciliopathy-associated COPD endotype

Jeanne-Marie Perotin , Myriam Polette , Gaëtan Deslée , Valérian Dormoy
Respiratory Research, 2021, 22 (1), ⟨10.1186/s12931-021-01665-4⟩
Article dans une revue hal-03170356 v1
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ZO-1 Intracellular Localization Organizes Immune Response in Non-Small Cell Lung Cancer

Déborah Neyrinck-Leglantier , Julien Lesage , Silvia Blacher , Arnaud Bonnomet , Walter Hunziker et al.
Frontiers in Cell and Developmental Biology, 2021, 9, pp.749364. ⟨10.3389/fcell.2021.749364⟩
Article dans une revue hal-03470162 v1
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An innate contribution of human nicotinic receptor polymorphisms to COPD-like lesions

Julie Routhier , Stéphanie Pons , Mohamed Lamine Freidja , Véronique Dalstein , Jérôme Cutrona et al.
Nature Communications, 2021, 12, pp.6384. ⟨10.1038/s41467-021-26637-6⟩
Article dans une revue pasteur-03414373 v1
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Airway epithelial cell differentiation relies on deficient Hedgehog signalling in COPD

Randa Belgacemi , Emilie Luczka , Julien Ancel , Zania Diabasana , Jeanne-Marie Perotin et al.
EBioMedicine, 2020, 51, pp.102572. ⟨10.1016/j.ebiom.2019.11.033⟩
Article dans une revue hal-02431914 v1
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Sonic hedgehog signalling as a potential endobronchial biomarker in COPD

Julien Ancel , Randa Belgacemi , Jeanne-Marie Perotin , Zania Diabasana , Sandra Dury et al.
Respiratory Research, 2020, 21 (1), ⟨10.1186/s12931-020-01478-x⟩
Article dans une revue hal-03038037 v1
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Nicotinic Receptor Subunits Atlas in the Adult Human Lung

Zania Diabasana , Jeanne-Marie Perotin , Randa Belgacemi , Julien Ancel , Pauline Mulette et al.
International Journal of Molecular Sciences, 2020, 21 (20), pp.7446. ⟨10.3390/ijms21207446⟩
Article dans une revue pasteur-02975996 v1

Asthme et obésité : mécanismes et pistes thérapeutiques

C. Guguen , C. Launois , V. Dormoy , M. Dewolf , A. Dumazet et al.
Revue des Maladies Respiratoires, 2019, ⟨10.1016/j.rmr.2019.03.015⟩
Article dans une revue hal-02431921 v1
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Intraductal patient‐derived xenografts of estrogen receptor α‐positive (ER+) breast cancer recapitulate the histopathological spectrum and metastatic potential of human lesions

Maryse Fiche , Valentina Scabia , Patrick Aouad , Laura Battista , Assia Treboux et al.
Journal of Pathology, 2019, 247 (3), pp.287-292. ⟨10.1002/path.5200⟩
Article dans une revue hal-02431932 v1
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The Lim1 oncogene as a new therapeutic target for metastatic human renal cell carcinoma

Imene Hamaidi , Catherine Coquard , Sabrina Danilin , Valérian Dormoy , Claire Béraud et al.
Oncogene, 2019, 38 (1), pp.60-72. ⟨10.1038/s41388-018-0413-y⟩
Article dans une revue hal-02431944 v1
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Alteration of primary cilia in COPD

Jeanne-Marie Perotin , Christelle Coraux , Eymeric Lagonotte , Philippe L. Birembaut , Gonzague Delepine et al.
European Respiratory Journal, 2018, 52 (1), pp.1800122. ⟨10.1183/13993003.00122-2018⟩
Article dans une revue hal-02431953 v1
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Managing patients with chronic cough: challenges and solutions

Jeanne-Marie Perotin , Claire Launois , Maxime Dewolf , Antoine Dumazet , Sandra Dury et al.
Therapeutics and Clinical Risk Management, 2018, Volume 14, pp.1041-1051. ⟨10.2147/TCRM.S136036⟩
Article dans une revue hal-02431951 v1

A Preclinical Model for ERα-Positive Breast Cancer Points to the Epithelial Microenvironment as Determinant of Luminal Phenotype and Hormone Response

George Sflomos , Valérian Dormoy , Tauno Metsalu , Rachel Jeitziner , Laura Battista et al.
Cancer Cell, 2016, 29 (3), pp.407-422. ⟨10.1016/j.ccell.2016.02.002⟩
Article dans une revue hal-02431957 v1

Targeting FAK scaffold functions inhibits human renal cell carcinoma growth

Claire Béraud , Valérian Dormoy , Sabrina Danilin , Véronique Lindner , Audrey Bethry et al.
International Journal of Cancer, 2015, 137 (7), pp.1549-1559. ⟨10.1002/ijc.29522⟩
Article dans une revue hal-03013677 v1

Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: focus on the cancer hallmark of tumor angiogenesis

Zhiwei Hu , Samira Brooks , Valérian Dormoy , Chia-Wen Hsu , Hsue-Yin Hsu et al.
Carcinogenesis, 2015, 36 (Suppl 1), pp.S184-S202. ⟨10.1093/carcin/bgv036⟩
Article dans une revue hal-04793687 v1
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Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead.

William H Goodson , Leroy Lowe , David O Carpenter , Michael Gilbertson , Abdul Manaf Ali et al.
Carcinogenesis, 2015, 36 (Suppl 1), pp.S254-96. ⟨10.1093/carcin/bgv039⟩
Article dans une revue pasteur-01352152 v1

Medical perspectives of metabolomics: the example of renal carcinoma

Valérian Dormoy , Thierry Massfelder
Médecine/Sciences, 2013, 29 (5), pp.463-468. ⟨10.1051/medsci/2013295007⟩
Article dans une revue hal-04791491 v1

Vitamin D3 triggers antitumor activity through targeting hedgehog signaling in human renal cell carcinoma

Valérian Dormoy , Claire Beraud , Véronique Lindner , Catherine Coquard , Mariette Barthelmebs et al.
Carcinogenesis, 2012, 33 (11), pp.2084-2093. ⟨10.1093/carcin/bgs255⟩
Article dans une revue hal-04795771 v1

New insights into vitamin D3 derivates for the prevention and the treatment of renal cell carcinoma

Valérian Dormoy , Claire Béraud , Véronique Lindner , Catherine Coquard , David Brasse et al.
European Urology Supplements, 2012, 11 (1), pp.e204-e204a. ⟨10.1016/S1569-9056(12)60201-2⟩
Article dans une revue istex hal-03721366 v1

From Development to Cancer: Lessons from the Kidney to Uncover New Therapeutic Targets

Valérian Dormoy , Didier Jacqmin , Hervé Lang , Thierry Massfelder
Anticancer Research, 2012, 32 (9), pp.3609-3617
Article dans une revue hal-04799461 v1

LIM-class homeobox gene Lim1, a novel oncogene in human renal cell carcinoma

Valérian Dormoy , C Béraud , V Lindner , L Thomas , C Coquard et al.
Oncogene, 2010, 30 (15), pp.1753-1763. ⟨10.1038/onc.2010.557⟩
Article dans une revue hal-04796108 v1
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The sonic hedgehog signaling pathway is reactivated in human renal cell carcinoma and plays orchestral role in tumor growth.

Valérian Dormoy , Sabrina Danilin , Véronique Lindner , Lionel Thomas , Sylvie Rothhut et al.
Molecular Cancer, 2009, 8 (1), pp.123. ⟨10.1186/1476-4598-8-123⟩
Article dans une revue inserm-00663549 v1

Altérations bronchiques et bronchiolaires au cours de la BPCO

Valérian Dormoy
CPLF (Congrès de Pneumologie de Langue Française), Jan 2024, Lille (France), France
Communication dans un congrès hal-04639812 v1

Actualités Asthme Sévère : l'année 2022 en revue. Recherche fondamentale.

Valérian Dormoy
Journées d'Echange sur l'Asthme Sévère (JEAS), Sep 2023, La Rochelle, France
Communication dans un congrès hal-04402340 v1

Les ciliogénèses dans l'asthme: identification, caractérisation et exploitation.

Valérian Dormoy
Journée CRISALIS, Mar 2023, PARIS, France
Communication dans un congrès hal-04402297 v1

Impact du SNPα5 (rs16969968) sur la ciliogenèse de l’épithélium respiratoire dans la BPCO

L. Saber Cherif , Z. Diabasana , J.M. Perotin , J. Ancel , M. Polette et al.
Journées de Recherche Respiratoire (J2R), 2021, Brest, France. pp.112-113, ⟨10.1016/j.rmr.2022.02.012⟩
Communication dans un congrès hal-03844832 v1

Implication du SNPα5 dans la bronchopneumopathie chronique obstructive

Z. Diabasana , R. Belgacemi , J. Ancel , J. Routhier , P. Birembaut et al.
Journées de Recherche Respiratoire (J2R), Oct 2020, Brest, France. pp.576-577, ⟨10.1016/j.rmr.2021.02.017⟩
Communication dans un congrès hal-03286828 v1

Etude des associations entre dérégulations associées aux cils dans l’épithélium des voies aériennes et phénotypes asthmatiques

Maëva A. Devilliers , Audrey Brisebarre , Laure Petit , Myriam Polette , Gaëtan Deslee et al.
Journées de Recherche Respiratoire (J2R), Oct 2023, Tours, France. ⟨10.1016/j.rmr.2024.01.011⟩
Poster de conférence hal-04402613 v1

Identification des gènes associés au programme de ciliogenèse primaire dans les maladies respiratoires chroniques

Sara Hatoum , Randa Belgacemi , Gaëtan Deslee , Myriam Polette , J.M. Perotin et al.
Journées de Recherche Respiratoire (J2R), Oct 2023, Tours, France. 41 (3), pp.191, 2024, ⟨10.1016/j.rmr.2024.01.022⟩
Poster de conférence hal-04402657 v1

Gene environment interaction in COPD: Involvement of a nicotinic receptor gene polymorphism

L. Massara , L. Saber Cherif , Stéphanie Pons , G. Kervoaze , A. Ollivier et al.
Journées de Recherche Respiratoire (J2R), Oct 2022, Reims, France. 40 (2), pp.115, 2023, ⟨10.1016/j.rmr.2022.11.014⟩
Poster de conférence hal-04021222 v1

Caractérisation des marqueurs pulmonaires de la voie Hedgehog dans la bronchopneumopathie chronique obstructive

L. Petit , R. Belgacemi , J. Ancel , P. Mulette , M. Polette et al.
Journées de Recherche Respiratoire (J2R), Oct 2022, Reims, France. 40 (2), pp.116-117, 2023, ⟨10.1016/j.rmr.2022.11.017⟩
Poster de conférence hal-04020843 v1

Impact of rs16969968 polymorphism (SNPα5) on epithelial differentiation in COPD patients

Lynda Saber Cherif , Zania Diabasana , Jeanne‐marie Perotin , Julien Ancel , Uwe Maskos et al.
ERS, Sep 2022, Barcelone (ES), Spain. ⟨10.1183/13993003.congress-2022.1288⟩
Poster de conférence hal-04601595 v1

Implication des récepteurs nicotiniques dans la bronchopneumopathie Chronique Obstructive

Z. Diabasana , R. Belgacemi , J. Routhier , P. Birembaut , U. Maskos et al.
Journées de Recherche Respiratoire (J2R), Oct 2020, Brest, France. 38 (6), pp.576, 2021, ⟨10.1016/j.rmr.2021.02.016⟩
Poster de conférence hal-03286866 v1