Access content directly

Valerie Leclere

Researcher identifiers



Kawal: A fermented food as a source of Bacillus strain producing antimicrobial peptides

Blaise Waongo , Maude Pupin , Matthieu Duban , Gabrielle Chataigne , Oumarou Zongo
Scientific African, 2023, 20, pp.e01714. ⟨10.1016/j.sciaf.2023.e01714⟩
Journal articles hal-04426241v1
Image document

The diversity of lipopeptides in the Pseudomonas syringae complex parallels phylogeny and sheds light on structural diversification during evolutionary history

Alexandre Bricout , Cindy E. Morris , Charlotte Chandeysson , Matthieu Duban , Corinne Boistel
Microbiology Spectrum, 2022, 10 (6), pp.e01456-22. ⟨10.1128/spectrum.01456-22⟩
Journal articles hal-03831557v1
Image document

Rhamnolipids and fengycins, very promising amphiphilic antifungal compounds from bacteria secretomes, act on Sclerotiniaceae fungi through different mechanisms

Camille Botcazon , Thomas Bergia , Didier Lecouturier , Chloé Dupuis , Alice Rochex
Frontiers in Microbiology, 2022, 13, pp.977633. ⟨10.3389/fmicb.2022.977633⟩
Journal articles hal-03823327v1
Image document

Editorial for the Special Issue “Microbial Nonribosomal Synthesis of Secondary Metabolites”

Stéphane Cociancich , Valérie Leclère
Microorganisms, 2022, 10 (5), pp.1064. ⟨10.3390/microorganisms10051064⟩
Journal articles hal-03792327v1
Image document

Nonribosomal Peptide Synthesis Definitely Working Out of the Rules

Matthieu Duban , Stéphane Cociancich , Valérie Leclère
Microorganisms, 2022, 10 (3), pp.577. ⟨10.3390/microorganisms10030577⟩
Journal articles hal-03645347v1
Image document

Dataset on phenotypic characterization, on protein and genome analysis of three fluorescent Pseudomonas strains from mid-mountain water

Elodie Dussert , Mélissa Tourret , Barbara Deracinois , Matthieu Duban , Valérie Leclère
Data in Brief, 2020, 30, pp.105466. ⟨10.1016/j.dib.2020.105466⟩
Journal articles hal-03898077v1

Palantir: a springboard for the analysis of secondary metabolite gene clusters in large-scale genome mining projects

Loïc Meunier , Pierre Tocquin , Luc Cornet , Damien Sirjacobs , Valérie Leclère
Bioinformatics, 2020, 36 (15), pp.4345-4347. ⟨10.1093/bioinformatics/btaa517⟩
Journal articles hal-03081849v1
Image document

Fluorescent Pseudomonas strains from mid-mountain water able to release antioxidant proteins directly into water

Elodie Dussert , Melissa Tourret , Barbara Deracinois , Matthieu Duban , Valérie Leclère
Microbiological Research, 2020, 236, pp.126444. ⟨10.1016/j.micres.2020.126444⟩
Journal articles hal-02930092v1
Image document

Pseudomonas sp. COW3 Produces New Bananamide-Type Cyclic Lipopeptides with Antimicrobial Activity against Pythium myriotylum and Pyricularia oryzae

Olumide Owolabi Omoboye , Niels Geudens , Matthieu Duban , Mickael Chevalier , Christophe Flahaut
Molecules, 2019, 24 (22), ⟨10.3390/molecules24224170⟩
Journal articles hal-02623494v1
Image document

Norine: update of the nonribosomal peptide resource

Areski Flissi , Emma Ricart , Clémentine Campart , Mickael Chevalier , Yoann Dufresne
Nucleic Acids Research, 2019, ⟨10.1093/nar/gkz1000⟩
Journal articles hal-02376009v1

Astin c production by the endophytic fungus cyanodermella asteris in planktonic and immobilized culture conditions

Antoine Vassaux , Cedric Tarayre , Anthony Arguelles-Arias , Philippe Compère , Frank Delvigne
Biotechnology Journal, 2019, 14 (8), pp.1-11. ⟨10.1002/biot.201800624⟩
Journal articles hal-02627915v1
Image document

rBAN: retro-biosynthetic analysis of nonribosomal peptides

Emma Ricart , Valérie Leclère , Areski Flissi , Markus Mueller , Maude Pupin
Journal of Cheminformatics, 2019, 11 (1), pp.1-14. ⟨10.1186/s13321-019-0335-x⟩
Journal articles hal-02167433v1
Image document

Nonribosomal peptides in fungal cell factories: from genome mining to optimized heterologous production

Antoine Vassaux , Loic Meunier , Micheline Vandenbol , Denis Baurain , Patrick P. Fickers
Biotechnology Advances, 2019, 37 (8), pp.1-23. ⟨10.1016/j.biotechadv.2019.107449⟩
Journal articles hal-02570530v1

Kendrick Mass Defect Approach Combined to NORINE Database for Molecular Formula Assignment of Nonribosomal Peptides

Mickael Chevalier , Emma Ricart , Emeline Hanozin , Maude Pupin , Philippe Jacques
Journal of The American Society for Mass Spectrometry, 2019, 30 (12), pp.2608-2616. ⟨10.1007/s13361-019-02314-3⟩
Journal articles hal-02417587v1

Lipopeptide biodiversity in antifungal Bacillus strains isolated from Algeria

Lamia Abdellaziz , Marlène Chollet , Ahmed Abderrahmani , Max Béchet , Lamia Yaici
Archives of Microbiology, 2018, 200 (8), pp.1205-1216. ⟨10.1007/s00203-018-1537-8⟩
Journal articles hal-02620924v1
Image document

Paraburkholderia phytofirmans PsJN-Plants Interaction: From Perception to the Induced Mechanisms

Qassim Esmaeel , Lidiane Miotto , Marine Rondeau , Valérie Leclère , Christophe Clément
Frontiers in Microbiology, 2018, 9, ⟨10.3389/fmicb.2018.02093⟩
Journal articles hal-02620923v1
Image document

Paraburkholderia phytofirmans PsJN-Plants Interaction: From Perception to the Induced Mechanisms

Qassim Esmaeel , Lidiane Miotto , Marine Rondeau , Valérie Leclère , Christophe Clément
Frontiers in Microbiology, 2018, 9, ⟨10.3389/fmicb.2018.02093⟩
Journal articles hal-02945059v1

Bioinformatics tools for the discovery of new lipopeptides with biocontrol applications

Maude Pupin , Areski Flissi , Philippe Jacques , Valérie Leclère
European Journal of Plant Pathology, 2018, ⟨10.1007/s10658-018-1544-2⟩
Journal articles hal-01937890v1

Nonribosomal peptides and polyketides of Burkholderia: new compounds potentially implicated in biocontrol and pharmaceuticals

Qassim Esmaeel , Maude Pupin , Philippe Jacques , Valérie Leclère
Environmental Science and Pollution Research, 2017, ⟨10.1007/s11356-017-9166-3⟩
Journal articles hal-01548616v1

Production of Bacillus amyloliquefaciens OG and its metabolites in renewable media: valorisation for biodiesel production and p -xylene decontamination

Augusto Etchegaray , François Coutte , Gabrielle Chataigné , Max Béchet , Ramon H.Z. dos Santos
Canadian Journal of Microbiology, 2017, 63 (1), pp.46-60. ⟨10.1139/cjm-2016-0288⟩
Journal articles hal-04431716v1

Nonribosomal peptide synthetase with a unique iterative-alternative-optional mechanism catalyzes amonabactin synthesis in Aeromonas

Qassim Esmaeel , Mickael Chevalier , Gabrielle Chataigne , Rathinasamy Subashkumar , Philippe Jacques
Applied Microbiology and Biotechnology, 2016, 100 (19), pp.8453-8463. ⟨10.1007/s00253-016-7773-4⟩
Journal articles hal-01601408v1
Image document

Burkholderia genome mining for nonribosomal peptide synthetases reveals a great potential for novel siderophores and lipopeptides synthesis

Qassim Esmaeel , Maude Pupin , Nam Phuong Kieu , Gabrielle Chataigné , Max Béchet
MicrobiologyOpen, 2016, 5 (3), pp.512 - 526. ⟨10.1002/mbo3.347⟩
Journal articles hal-01398944v1
Image document

Smiles2Monomers: a link between chemical and biological structures for polymers

Yoann Dufresne , Laurent Noé , Valérie Leclère , Maude Pupin
Journal of Cheminformatics, 2015, 7, ⟨10.1186/s13321-015-0111-5⟩
Journal articles hal-01250619v1
Image document

Norine, the knowledgebase dedicated to non-ribosomal peptides, is now open to crowdsourcing

Areski Flissi , Yoann Dufresne , Juraj Michalik , Laurie Tonon , Stéphane Janot
Nucleic Acids Research, 2015, ⟨10.1093/nar/gkv1143⟩
Journal articles hal-01235996v1
Image document

Norine: a powerful resource for novel nonribosomal peptide discovery

Maude Pupin , Qassim Esmaeel , Areski Flissi , Yoann Dufresne , Philippe Jacques
Synthetic and Systems Biotechnology, 2015, ⟨10.1016/j.synbio.2015.11.001⟩
Journal articles hal-01250614v1

Characterization of Cichopeptins, New Phytotoxic Cyclic Lipodepsipeptides Produced by Pseudomonas cichorii SF1-54 and Their Role in Bacterial Midrib Rot Disease of Lettuce

Chien-Jui Huang , Ellen Pauwelyn , Marc Ongena , Delphine Debois , Valérie Leclère
Molecular Plant-Microbe Interactions, 2015, 28 (9), pp.1009-1022. ⟨10.1094/MPMI-03-15-0061-R⟩
Journal articles hal-02947767v1

To settle or to move? The interplay between two classes of cyclic lipopeptides in the biocontrol strain P seudomonas CMR12a

Jolien d'Aes , Nam Phuong Kieu , Valérie Leclère , Caroline Tokarski , Feyisara Eyiwumi Olorunleke
Environmental Microbiology, 2014, 16 (7), pp.2282-2300. ⟨10.1111/1462-2920.12462⟩
Journal articles hal-02945870v1
Image document

Prediction of New Bioactive Molecules using a Bayesian Belief Network

Ammar Abdo , Valérie Leclère , Philippe Jacques , Naomie Salim , Maude Pupin
Journal of Chemical Information and Modeling, 2014, 54 (1), pp.30-36. ⟨10.1021/ci4004909⟩
Journal articles hal-01090611v1
Image document

Prediction of Monomer Isomery in Florine: A Workflow Dedicated to Nonribosomal Peptide Discovery

Thibault Caradec , Maude Pupin , Aurélien Vanvlassenbroeck , Marie-Dominique Devignes , Malika Smaïl-Tabbone
PLoS ONE, 2014, 9 (1), pp.e85667. ⟨10.1371/journal.pone.0085667⟩
Journal articles hal-01090619v1

New Linear Lipopeptides Produced by Pseudomonas cichorii SF1-54 Are Involved in Virulence, Swarming Motility, and Biofilm Formation

Ellen Pauwelyn , Chien-Jui Huang , Marc Ongena , Valérie Leclère , Philippe Jacques
Molecular Plant-Microbe Interactions, 2013, 26 (5), pp.585-598. ⟨10.1094/MPMI-11-12-0258-R⟩
Journal articles hal-02945832v1

New integrated bioprocess for the continuous production, extraction and purification of lipopeptides produced by Bacillus subtilis in membrane bioreactor

François Coutte , Didier Lecouturier , Valérie Leclère , Max Béchet , Philippe Jacques
Process Biochemistry, 2013, 48 (1), pp.25-32. ⟨10.1016/j.procbio.2012.10.005⟩
Journal articles hal-03885995v1
Image document

Production of a novel mixture of mycosubtilins by mutants of Bacillus subtilis

Max Béchet , Joany Castéra-Guy , Jean-Sebastien Guez , Nour-Eddine Chihib , Françoise Coucheney
Bioresource Technology, 2013, 145, pp.264-270. ⟨10.1016/j.biortech.2013.03.123⟩
Journal articles hal-02938868v1
Image document

Structure, biosynthesis, and properties of kurstakins, nonribosomal lipopeptides from Bacillus spp.

Max Béchet , Thibault Caradec , Walaa Hussein , Ahmed Abderrahmani , Marlène Chollet
Applied Microbiology and Biotechnology, 2012, 95 (3), pp.593-600. ⟨10.1007/s00253-012-4181-2⟩
Journal articles hal-00749819v1
Image document

A new fingerprint to predict nonribosomal peptides activity.

Ammar Hasan Abdo , Ségolène Caboche , Valérie Leclère , Philippe Jacques , Maude Pupin
Journal of Computer-Aided Molecular Design, 2012, 26 (10), pp.1187-94. ⟨10.1007/s10822-012-9608-4⟩
Journal articles hal-00750002v1
Image document

Diversity of monomers in nonribosomal peptides: towards the prediction of origin and biological activity.

Ségolène Caboche , Valérie Leclère , Maude Pupin , Gregory Kucherov , Philippe Jacques
Journal of Bacteriology, 2010, 192 (19), pp.5143-50. ⟨10.1128/JB.00315-10⟩
Journal articles hal-00641488v1

Production of surfactin and fengycin by Bacillus subtilis in a bubbleless membrane bioreactor

François Coutte , Didier Lecouturier , Saliha Ait Yahia , Valérie Leclère , Max Béchet
Applied Microbiology and Biotechnology, 2010, 87 (2), pp.499-507. ⟨10.1007/s00253-010-2504-8⟩
Journal articles hal-03886581v1
Image document

Effect of pps disruption and constitutive expression of srfA on surfactin productivity, spreading and antagonistic properties of Bacillus subtilis 168 derivatives

François Coutte , Valérie Leclère , Max Béchet , Jean-Sebastien Guez , Didier Lecouturier
Journal of Applied Microbiology, 2010, 109 (2), pp.480-491. ⟨10.1111/j.1365-2672.2010.04683.x⟩
Journal articles hal-02939416v1
Image document

High-Level Biosynthesis of the Anteiso-C17 Isoform of the Antibiotic Mycosubtilin in Bacillus subtilis and Characterization of Its Candidacidal Activity

Patrick Fickers , Jean-Sebastien Guez , Christian Damblon , Valérie Leclère , Max Béchet
Applied and Environmental Microbiology, 2009, 75 (13), pp.4636-4640. ⟨10.1128/AEM.00548-09⟩
Journal articles hal-02941974v1
Image document

Structural pattern matching of nonribosomal peptides.

Ségolène Caboche , Maude Pupin , Valérie Leclère , Philippe Jacques , Gregory Kucherov
BMC Structural Biology, 2009, 9 (15), ⟨10.1186/1472-6807-9-15⟩
Journal articles hal-00641486v1
Image document

NORINE: a database of nonribosomal peptides.

Ségolène Caboche , Maude Pupin , Valérie Leclère , Arnaud Fontaine , Philippe Jacques
Nucleic Acids Research, 2008, Database issue, 36 (Database issue), pp.D326-31. ⟨10.1093/nar/gkm792⟩
Journal articles inria-00281012v1
Image document

Temperature dependence of mycosubtilin homologue production in Bacillus subtilis ATCC6633

Patrick Fickers , Valérie Leclère , Jean-Sebastien Guez , Max Béchet , Françoise Coucheney
Research in Microbiology, 2008, ⟨10.1016/j.resmic.2008.05.004⟩
Journal articles hal-02938954v1

La synthèse peptidique non-ribosomique, source de biodiversité de composés actifs.

Frédérique Gancel , Philippe Jacques , Marlène Chollet-Imbert , Jean-Sebastien Guez , Max Béchet
Bulletin de la Société Française Microbiologie, 2007
Journal articles hal-03875506v1
Image document

Mycosubtilin Overproduction by Bacillus subtilis BBG100 Enhances the Organism's Antagonistic and Biocontrol Activities

Valérie Leclère , Max Béchet , Akram Adam , Jean-Sebastien Guez , Bernard Wathelet
Applied and Environmental Microbiology, 2005, 71, pp.4577 - 4584. ⟨10.1128/AEM.71.8.4577-4584.2005⟩
Journal articles hal-02938999v1

Bioinformatics tools for the discovery of new lipopeptides with biocontrol applications

M. Pupin , A. Flissi , P. Jacques , Valérie Leclère
Joint Conference of the 12. Conference of the European-Foundation-for-Plant-Pathology (EFPP) / 10. Conference of the French-Society-for-Phytopathology (SFP), May 2017, Dordrecht, France. pp.9, ⟨10.1007/s10658-018-1544-2⟩
Conference papers hal-02736923v1

Nonribosomal peptides and polyketides of Burkholderia: new compounds potentially implicated in biocontrol and pharmaceuticals

Qassim Esmaeel , Maude Pupin , Philippe Jacques , Valérie Leclère
3. Biennial International Congress on Natural Products and Biocontrol, Sep 2016, Perpignan, France. ⟨10.1007/s11356-017-9166-3⟩
Conference papers hal-02737697v1

Directed Biosynthesis of Antifungal and Biosurfactant Lipopeptides from Bacillus subtilis.

Philippe Jacques , François Coutte , Max Béchet , Jean-Sebastien Guez , Valérie Leclère
10th European Symposium of Biochemical Science (ESBES) and 6th International Forum on Industrial Bioprocesses, Sep 2014, Lille, France
Conference papers hal-03877026v1

Novel biosurfactants with biocontrol activity and low ecotoxicity.

Philippe Jacques , Max Béchet , Joany Castéra-Guy , Nour-Eddine Chihib , François Coutte
9th European Congress of Chemical Engineering / 2nd European Congress of Applied Biotechnology, Apr 2013, The Hague, Netherlands
Conference papers hal-03876487v1
Image document

Non Ribosomal Peptides : A monomeric puzzle

Yoann Dufresne , Valérie Leclère , Philippe Jacques , Laurent Noé , Maude Pupin
JOBIM - Journées Ouvertes en Biologie, Informatique et Mathématiques, Jul 2013, Toulouse, France. pp.143-150
Conference papers hal-00843827v1

Synthetic Engineering of Bacillus subtilis to Overproduce Lipopeptide Biosurfactants

François Coutte , Mathias John , Max Béchet , Mirabelle Nebut , Joachim Niehren
9th European Symposium on Biochemical Engineering Science, Sep 2012, Istanbul, Turkey
Conference papers hal-00717261v1
Image document

NRPS toolbox for the discovery of new nonribosomal peptides and synthetases

Maude Pupin , Malika Smaïl-Tabbone , Philippe Jacques , Marie-Dominique Devignes , Valérie Leclère
Journées Ouvertes en Biologie, l'Informatique et les Mathématiques - JOBIM 2012, Jul 2012, Rennes, France. pp.89-93
Conference papers hal-00734312v1

Les lipopeptides de Bacillus sp. : des molécules à haut potentiel pour la lutte biologique contre les champignons phytopathogènes

Philippe Jacques , Max Béchet , François Coutte , Jovana Deravel , Jean-Sebastien Guez
3éme Journée du Groupe Francophone d’Étude des Pesticides Organiques d’Origine Naturelle, Jun 2010, Lyon, France
Conference papers hal-03877273v1

Relationship between temperature, branched fatty acid synthesis and mycosubtilin isoform production in Bacillus subtilis.

Jean-Sebastien Guez , Patrick Fickers , Max Béchet , Valérie Leclère , Françoise Coucheney
BACELL, Apr 2009, Copenhagen, Denmark
Conference papers hal-03876081v1

Bacillus lipopeptides leading to versatile weapons for plant disease biocontrol.

Valérie Leclère , Max Béchet , Alain Brans , François Coutte , Marlène Chollet-Imbert
Bacell, Mar 2008, oslo, Sweden
Conference papers hal-03876008v1

Genetic and bioprocess engineering applied to the overproduction of biosurfactant from Bacillus subtilis.

Philippe Jacques , Valérie Leclère , Max Béchet , François Coutte , Marlène Chollet-Imbert
International Congress on Bioprocesses in Food Industries, Nov 2008, Hyderabad, India
Conference papers hal-03876051v1

Biosynthèse dirigée de molécules peptidiques actives synthétisées par le mécanisme non ribosomal

Philippe Jacques , Max Béchet , Marlène Chollet-Imbert , Françoise Coucheney , Frédérique Gancel
7ème congrès national de la Société Française de Microbiologie, May 2007, Nantes, France
Conference papers hal-03877236v1

Optimisation de la production de biosurfactants par Bacillus subtilis

Philippe Jacques , Jean-Sebastien Guez , Benjamin Destée , Valérie Leclère , Max Béchet
10ème congrès de la Société Française de Génie des Procédés (SFGP), Sep 2005, Toulouse, France
Conference papers hal-03877554v1

Optimisation strategies of antibiotic lipopeptide production by Bacillus subtilis

Valérie Leclère , Max Béchet , Frédérique Gancel , Jean-Sebastien Guez , Marlène Chollet-Imbert
5th European Symposium of Biochemical Science (ESBES), Sep 2004, Stuttgart, Germany
Conference papers hal-03877549v1
Image document

Norine, Florine, s2m : powerful bioinformatics resource and tools for the discovery of novel nonribosomal peptides, natural metabolites with versatile activities

Qassim Esmaeel , Yoann Dufresne , Areski Flissi , Maude Pupin , Philippe Jacques
FEMS 2017 - 7th congress of Federation of European Microbiology societies, Jul 2017, Valencia, Spain
Conference poster hal-01888999v1
Image document

Data updates on Norine, the reference Non-Ribosomal Peptide knowledge base

Yoann Dufresne , Juraj Michalik , Areski Flissi , Valérie Leclère , Maude Pupin
JOBIM 2017 - Journées Ouvertes en Biologie, Informatique et Mathématiques, Jul 2017, Lille, France
Conference poster hal-01889117v1

Consequences of both constitutive synthesis of surfactin and disruption of plipastatin operon on phenotypic properties of Bacillus subtilis

François Coutte , Valérie Leclère , Max Béchet , Jean-Sebastien Guez , Didier Lecouturier
5th International Conference on Functional Genomics of Gram-positive Microorganisms. 15th International Conference on Bacilli, Jun 2008, San Diego, United States
Conference poster hal-03877686v1

La synthèse non-ribosomique, un potentiel immense de peptides à activités biologiques

Françoise Coucheney , Valérie Leclère , Max Béchet , Frédérique Gancel , Marlène Chollet-Imbert
Club des Bactéries Lactiques, Nov 2007, Rennes, France
Conference poster hal-03877621v1

Influence of pH on the production of mycosubtilin, an antifungal metabolite from Bacillus subtilis with potential applications in agro-food sector

Jean-Sebastien Guez , Valérie Leclère , Max Béchet , Hervé Joiris , Philippe Jacques
International Congress on Bioprocesses in Food industries (ICBF), Jul 2004, Clermond-Ferrand, France
Conference poster hal-03877525v1

Norine: Bioinformatics Methods and Tools for the Characterization of Newly Discovered Nonribosomal Peptides

Areski Flissi , Matthieu Duban , Philippe Jacques , Valérie Leclère , Maude Pupin
Non-Ribosomal Peptide Biosynthesis and Engineering, 2670, Springer US, pp.303-318, 2023, Methods in Molecular Biology, 978-1-0716-3214-7. ⟨10.1007/978-1-0716-3214-7_16⟩
Book sections hal-04119620v1

The Role of Microbial Metabolites in Biological Control

Valérie Leclère , Christophe Clément , Stéphan Dorey , Claire Prigent-Combaret
Extended Biocontrol, Springer Netherlands, pp.137-145, 2022, ⟨10.1007/978-94-024-2150-7_12⟩
Book sections hal-03763599v1

Chapitre 12 : Les métabolites microbiens, acteurs du biocontrôle

Valérie Leclère , Stephan Dorey , Claire Pringent Combaret , Christophe Clement
Xavier Fauvergue, Adrien Rusch, Matthieu Barret et al. Biocontrôle : éléments pour une protection agroécologique des cultures, éditions Quae, pp.161-169, 2020, Savoir-faire (Paris. 2006), ISSN 1952-1251, 978-2-7592-3076-1
Book sections hal-03549491v1

Bioinformatics Tools for the Discovery of New Nonribosomal Peptides

Valérie Leclère , Tilmann Weber , Philippe Jacques , Maude Pupin
Bradley S. Evans. Nonribosomal Peptide and Polyketide Biosynthesis, 1401, Humana Press, pp.209-232, 2016, Methods in Molecular Biology, 978-1-4939-3373-0 978-1-4939-3375-4. ⟨10.1007/978-1-4939-3375-4_14⟩
Book sections hal-01398960v1