Vasile STUPAR

responsable du plateau préclinique de la plateforme IRMaGe
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Compétences

IRM préclinique SRM cérébrale préclinique Imagerie spéctroscopique Edition du GABA Ultrasons focalisés Ouverture de la BHE

Publications

Publications

Microbeam Radiation Therapy Opens a Several Days’ Vessel Permeability Window for Small Molecules in Brain Tumor Vessels

Marine Potez , Claire Rome , Benjamin Lemasson , Pierre Heemeryck , Jean Albert Laissue et al.
International Journal of Radiation Oncology, Biology, Physics, 2024, 119 (5), pp.1506-1516. ⟨10.1016/j.ijrobp.2024.02.007⟩
Article dans une revue hal-05142200 v1
Image document

In vivo characterization of physiological and metabolic changes related to isocitrate dehydrogenase 1 mutation expcression by multiparametric MRI and MRS in a rat model with orthotopically grafted human-derived glioblastoma cell lines

Alexandra Clément , Matthieu Doyen , Florence Fauvelle , Gabriela Hossu , Bailiang Chen et al.
NMR in Biomedicine, 2021, 34 (6), pp.e4490. ⟨10.1002/nbm.4490⟩
Article dans une revue hal-03159567 v1

Neurovascular multiparametric MRI defines epileptogenic and seizure propagation regions in experimental mesiotemporal lobe epilepsy

Fabien Boux , Florence Forbes , Nora Collomb , Emma Zub , Lucile Maziere et al.
Epilepsia, 2021, 62 (5), pp.1244-1255. ⟨10.1111/epi.16886⟩
Article dans une revue hal-03193021 v1

Hypertonic sodium lactate reverses brain oxygenation and metabolism dysfunction after traumatic brain injury

A. Millet , A. Cuisinier , P. Bouzat , C. Batandier , B. Lemasson et al.
British Journal of Anaesthesia, 2018, 120 (6), pp.1295-1303. ⟨10.1016/j.bja.2018.01.025⟩
Article dans une revue hal-04728897 v1

Hypertonic sodium lactate reverses brain oxygenation and metabolism dysfunction after traumatic brain injury

A. Millet , A. Cuisinier , P. Bouzat , C. Batandier , B. Lemasson et al.
British Journal of Anaesthesia, 2018, 120 (6), pp.1295 - 1303. ⟨10.1016/j.bja.2018.01.025⟩
Article dans une revue hal-01930811 v1

The three glioma rat models C6, F98 and RG2 exhibit different metabolic profiles: in vivo 1H MRS and ex vivo 1H HRMAS combined with multivariate statistics

Nicolas Coquery , Vasile Stupar , Regine Farion , Séverine Maunoir-Regimbal , Emmanuel L. Barbier et al.
Metabolomics, 2015, 11 (6), pp.1834-1847. ⟨10.1007/s11306-015-0835-2⟩
Article dans une revue hal-02430555 v1

Impact of manganese on the hippocampus metabolism in the context of MEMRI: a proton HRMAS MRS study

A. Daoust , E. Barbier , S. Bohic , V. Stupar , S. Maunoir-Regimbal et al.
Toxicology Research, 2015, 4 (2), pp.376-384. ⟨10.1039/c4tx00135d⟩
Article dans une revue hal-02430582 v1

Monochromatic minibeams radiotherapy: from healthy tissue-sparing effect studies toward first experimental glioma bearing rats therapy

P. Deman , M. Vautrin , M. Edouard , V. Stupar , L. Bobyk et al.
International Journal of Radiation Oncology, Biology, Physics, 2012, 82 (4), pp.e693-e700. ⟨10.1016/j.ijrobp.2011.09.013⟩
Article dans une revue hal-00850697 v1
Image document

Ultrasmall rigid particles as multimodal probes for medical applications.

François Lux , Anna Mignot , Pierre Mowat , Cédric Louis , Sandrine Dufort et al.
Angewandte Chemie International Edition, 2011, 50 (51), pp.12299-303. ⟨10.1002/anie.201104104⟩
Article dans une revue istex inserm-00658275 v1

Longitudinal 3He and proton imaging of magnetite biodistribution in a rat model of instilled nanoparticles

Achraf Al Faraj , Ghislaine Lacroix , Hasan Alsaid , Dan Elgrabli , Vasile Stupar et al.
Magnetic Resonance in Medicine, 2008, 59 (6), pp.1298-1303. ⟨10.1002/mrm.21571⟩
Article dans une revue istex ineris-00963121 v1

Measurement of nonlinear pO2 decay in mouse lungs using 3He-MRI, NMR in Biomedicine

K. Cieslar , H. Alsaid , V. Stupar , Sophie Gaillard , E. Canet-Soulas et al.
NMR Biomed., 2007
Article dans une revue hal-01922784 v1

Alveolar oxygen partial pressure and O2 depletion rate mapping in rats using 3He ventilation imaging

K. Cieslar , V. Stupar , E. Canet-Soulas , S. Gaillard , Y. Crémillieux
Magnetic Resonance in Medicine, 2007, 57, pp.423-430
Article dans une revue hal-00443195 v1

Retrospective Cine 3He ventilation imaging under spontaneous breathing conditions: a non-invasive protocol for small animal lung function imaging

V. Stupar , E. Canet-Soulas , S. Gaillard , H. Alsaid , N. Beckmann et al.
Nuclear Magnetic Resonance in Biomedicine, 2007, 20, pp.104-112
Article dans une revue hal-00443473 v1

Nonlinear pO(2) decay in mouse lungs using He-3-MRI

K. Cieslar , H. Alsaid , V. Stupar , S. Gaillard , E. Canet-Soulas et al.
Measurement of Nuclear Magnetic Resonance in Biomedicine, 2007, 57, pp.383-391
Article dans une revue hal-00443194 v1

Noninvasive hyperpolarized helium-3 imaging studies in rats under spontaneous breathing conditions using a retrospective radial cine imaging technique

V. Stupar , E. Canet-Soulas , Sophie Gaillard , H. Alsaid , N. Beckmann et al.
Contrast Media and Molecular Imaging, 2006
Article dans une revue hal-01922788 v1

Alveolar pO2 and oxygen uptake imaging in mice using 3He-MRI

K. Cieslar , H. Alsaid , V. Stupar , S. Gaillard , E. Canet-Soulas et al.
Nuclear Magnetic Resonance in Biomedicine, 2006, (in-press)
Article dans une revue hal-00443193 v1

Quantitative measurements of regional lung ventilation using helium3 MRI in a metacholine-induced bronchoconstriction model

K. Mosbah , Y. Crémillieux , P. Adeleine , D. Dupuich , V. Stupar et al.
J Magn Reson Imaging, 2006, 24 (3), pp.611-616
Article dans une revue hal-00443369 v1

Quantitative measurements of regional lung ventilation using helium-3 MRI in a methacholine-induced bronchoconstriction model

K. Mosbah , Y. Cremillieux , P. Adeleine , D. Dupuich , V. Stupar et al.
Journal of Magnetic Resonance Imaging, 2006, 24, pp.611-616. ⟨10.1002/jmri.20671⟩
Article dans une revue istex hal-00427995 v1

Longitudinal MR vascular fingerprinting approach tracking physiological changes during repeated MR guided focused ultrasound mediated BBB opening on rats

Sébastien Rigollet , Aurelien Delphin , Thomas Ador , Erik Dumont , Chantal Pichon et al.
19th European Molecular Imaging Meeting, Mar 2024, Porto, Portugal
Communication dans un congrès hal-04524090 v1
Image document

Longitudinal study tracking physiological changes through multiparametric MRI during repeated MRgFUS-induced BBB opening

Sébastien Rigollet , Thomas Ador , Erik Dumont , Chantal Pichon , Emmanuel L Barbier et al.
2024 International Society for Magnetic Resonance in Medecine & International Society for MR Radiographers & Technologists Annual Meeting & Exhibition, May 2024, Singapour, Singapore
Communication dans un congrès hal-04606240 v1

Cerebral perfusion monitoring after FUS mediated blood-brain barrier opening: a study to evaluate ultrasound bioeffect

Rigollet Sébastien , Anthony Delalande , Erik Dumont , Chantal Pichon , Emmanuel Barbier et al.
22nd Annual International Symposium on Therapeutic Ultrasound (ISTU 2023), Apr 2023, Lyon, France
Communication dans un congrès hal-04215096 v1

Brain Metabolic Disorders Induced by Convulsive Dose of Soman. In vivo Study Using Chemical Shift Imaging NMR Spectroscopy in Mice

G. Testylier , V. Stupar , F. Fauvelle , C. Rémy , H. Ratiney et al.
The XIII International congress of Toxicoloy, 2013, Séoul, Korea, Unknown Region. pp.P3 \textendash 068
Communication dans un congrès hal-01879525 v1

Brain Metabolic Disorders Induced by Convulsive Dose of Soman. In vivo Study Using Chemical Shift Imaging NMR Spectroscopy in Mice

G. Testylier , V. Stupar , F. Fauvelle , C. Rémy , H. Ratiney et al.
The XIII International congress of Toxicoloy, 2013, Séoul, Korea, Unknown Region. pp.P3 \textendash 068
Communication dans un congrès hal-01879521 v1

Hyperpolarisation de noyaux de C13 par Polarisation Dynamique Nucléaire pour la production d\textquoterightagents de contraste pour l\textquoterightIRM et la SRM biomédicales : principes, conception et implémentation

F. Goutailler , V. Stupar , S. Gaillard , B. Montcel , Y. Crémillieux
Congrès général de la Société Française de Physique, 2007, Grenoble, France
Communication dans un congrès hal-01912469 v1

Longitudinal Helium-3 and Proton imaging of magnetite biodistribution in a rat model of instilled nanoparticles.

A. Al Faraj , G. Lacroix , H. Alsaid , D. Elgrabi , V. Stupar et al.
International Society of Magnetic Resonance in Medicine, 2007, Berlin, Germany
Communication dans un congrès hal-01922783 v1

Hyperpolarisation de noyaux de C13 par Polarisation Dynamique Nucléaire (PDN) pour la production d\textquoterightagents de contraste pour l\textquoterightIRM et la SRM biomédicales

F. Goutailler , V. Stupar , B. Montcel , S. Gaillard , Y. Crémillieux
XXéme Congrès du GERM, 2007, Alénya, France
Communication dans un congrès hal-01912470 v1

A Dynamic Nuclear Polarization system for MRI and MRS in vivo hyperpolarised contrast agents: Principles, design and realisation

F. Goutailler , V. Stupar , B. Montcel , Y. Crémillieux
Dynamic Nuclear Polarization Symposium, 2007, Nottingham, United Kingdom
Communication dans un congrès hal-01912471 v1

Hyperpolarized 3He MRI: a comprehensive tool for the investigation of lung function in physio-pathological animal models

V. Stupar , A. Al Faraj , H. Alsaid , Elise Bannier , K. Cieslar et al.
Contrast Media Research - CMR, 2007, Banff, Canada
Communication dans un congrès hal-01922785 v1

Measurement of nonlinear decay of alveolar partial pressure of oxygen in mice using 3He-MR

K. Cieslar , H. Alsaid , V. Stupar , Sophie Gaillard , R. Fissoune et al.
ISMRM, 2006, Seattle, USA, Unknown Region
Communication dans un congrès hal-01922787 v1

Retrospective Cine 3He ventilation imaging under spontaneous breathing conditions: a non invasive imaging protocol for small animal lung function imaging

V. Stupar , E. Canet-Soulas , H. Alsaid , Sophie Gaillard , N. Beckmann et al.
ISMRM, 2006, Seattle, USA, Unknown Region
Communication dans un congrès hal-01922789 v1

Mapping of Alveolar Initial Partial Pressure of Oxygen end Depletion Rate in Rats and Mice

K. Cieslar , V. Stupar , E. Canet-Soulas , Sophie Gaillard , Y. Crémillieux
Winnipeg Workshop, 2005, Krakow, Poland
Communication dans un congrès hal-01922790 v1

Retrospective Cine ventilation imaging under spontaneous breathing conditions: a non invasive imaging protocol for rat lung function assessment

V. Stupar , E. Canet-Soulas , Sophie Gaillard , H. Alsaid , N. Beckmann et al.
European Society for Magnetic Resonance in Medicine and Biology, 22nd Annual Scientific Meeting ESMRMB, 2005, Basel, Switzerland. (in-press)
Communication dans un congrès hal-01922791 v1
Image document

Optimisation de l'ouverture de la barrière hémato-encéphalique contrôlé par IRM sur cerveau entier

Sébastien Rigollet , Romain Clément , Cassandra Cresson , Emmanuel Barbier , Anthony Delalande et al.
6ème congrès de la Société Française de Résonance Magnétique en Biologie et Médecine, Mar 2023, Paris Sorbonne Université, France
Poster de conférence hal-04215027 v1

Ultrasound and Cationic Microbubble Assisted Gene Delivery in the Brain for Fragile X Syndrome Therapy

C. Delehedde , V. de Concini , R. Clémençon , C. Si Ahmed , Sandra Même et al.
French Society of Nanomedicine and C’Nano Joint conference, Dec 2019, Dijon, France
Poster de conférence hal-03668578 v1

Impact of focused ultrasound on cerebral blood flow

V. Stupar , Anthony Delalande , N. Collomb , C. Rome , E. And Barbier
Joint Annual Meeting ISMRM-ESMRMB, Jun 2018, Paris, France
Poster de conférence hal-03668579 v1