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Vincent AUCAGNE

22
Documents
Identifiants chercheurs

Présentation

EDUCATION --------- - 1999-2002 - PhD in organic chemistry with higher honors, Université d'Orléans defended in 2003, grant from the French Ministry of Research and Technology - 1998-1999 -Master in chemistry and physicochemistry of bioactive compounds with higher honors, Universités Paris V, Paris XI and Orléans PROFESSIONAL EXPERIENCES ------------------------ - 2006 - CNRS Research manager, Centre de Biophysique Moléculaire, Orléans - Team of Dr A. Delmas, Development of new tools for the solid-phase total synthesis of native or modified proteins and glycoproteins - 2004-2006 - Postdoctoral Research Associate, School of Chemistry, University of Edinburgh UK - Team of Prof. D. A. Leigh, Towards the total synthesis of the lasso peptide Microcin J25; Active template methodologies for the synthesis of mechanically-interlocked architectures - 2002-2003 - Fixed-term Lecturer in organic chemistry (ATER, one year fellowship) Université d'Orléans - Institut de Chimie Organique et Analytique (I.C.O.A.), Team of Prof. L. A. Agrofoglio, synthesis of new nucleoside analogues with antiviral activities - 1999-2002 - PhD in organic chemistry , I.C.O.A., team of Prof. P. Rollin Sulfur-containing phosphonium salts and anomeric Wittig reaction. Evaluation of vinylthio-functionalized alditols – new tools for stereocontrolled ring closure reactions - 1998-1998 - Postgraduate research fellow , I.C.O.A.; team of Prof. P. Rollin Synthesis of C-glycosidic analogues of glucosinolates RESEARCH INTERESTS ------------------ - Synthetic chemistry of biomacromolecules : Total synthesis of small proteins and glycoproteins. Click chemistry. Native chemical ligation Amino-acids, carbohydrates and nucleoside analogues. Modified or bioconjugated proteins. Synthetic vaccines. Drug-delivery. - Solid-phase organic synthesis : Solid-phase peptide and bio-macromolecule ligation. Solid-phase purification - Supramolecular Chemistry : Rotaxanes, Catenanes, Mechanically-interlocked architectures. Coordination chemistry - Thiochemistry : Thioester and thioacid peptides. Sulfonylated strained aminoacids. Sulfur as a tool in organic and bioorganic chemistry. - Referee for Letters in Organic Chemistry, the Journal of Organic Chemistry, the Journal of the American Chemical Society. Member of the French and American Chemical Societies

Publications

"dlomet"

Rational design of kisspeptin analogs for the control of reproduction

T.M. Vishwanatha , C. Decourt , V.P. Terrier , V. Robert , M. Galibert
4th Belgian Peptide Group Meeting, Feb 2018, Bruxelles, Belgium
Communication dans un congrès hal-02892809v1

Design and profiling of new selective KISS1R agonists that stimulate the reproductive system

Massimiliano Beltramo , Vincent Aucagne , Vincent Robert , Mathieu Galibert , Jean-Baptiste Madinier
8. International Congress of Neuroendocrinology, Society for Behavioral Neuroendocrinology (SBN). USA., Aug 2014, Sydney, Australia
Communication dans un congrès hal-02738894v1

New KISS1R agonists with potential for the treatment of reproductive disorder

Massimiliano Beltramo , Vincent Aucagne , Vincent Robert , Mathieu Galibert , Jean-Baptiste Madinier
11. International Symposium on GnRH: The hypothalamic-pituitary-gonadal axis in cancer and reproduction, Kenes International. USA., Feb 2014, Salzburg, Austria
Communication dans un congrès hal-02742248v1

Rational design of kisspeptin analogs for the control of the reproductive system

T.M. Vishwanatha , C. Decourt , V.P. Terrier , V. Robert , J.-B. Madinier
25th SCT Young Research Fellows meeting, Mar 2018, Orléans, France
Poster de conférence hal-02894277v1
Image document

In non-breeding ewes the kisspeptin analog c6 triggers ovulation without progestogen priming

Massimiliano Beltramo , Caroline Decourt , Vincent Robert , Didier Lomet , Vincent Aucagne
9th International Congress of Neuroendocrinology, Jul 2018, Toronto, Canada. , 2018, The 9th International Congress of Neuroendocrinology. Abstract book
Poster de conférence hal-02735160v1

Long-lasting increase of gonadotropins by rational design of lipophilic kisspeptin analogs

T.M. Vishwanatha , C. Decourt C , V. Robert , M. Galibert , J.-B. Madinier
2018 International Symposium on Chemical Biology, Jan 2018, Genève, Switzerland
Poster de conférence hal-02894282v1

The kisspeptin analog C6 triggers ovulation in non-breeding ewe in the absence of progestogen priming

C. Decourt , V. Robert , Didier Lomet , V. Aucagne , Massimiliano Beltramo
9. International Congress of Neuroendocrinology (ICN 2018), Jul 2018, Toronto, Canada
Poster de conférence hal-02894264v1

Investigation of tachyphylaxis of LH response following repeated injections of the kisspeptin analog C6

Caroline Decourt , Vincent Robert , Didier Lomet , Karine Anger , A. Delmas
Colloque International NeuroFrance 2017, May 2017, Bordeaux, France. 2017, Colloque International NeuroFrance 2017
Poster de conférence hal-01605114v1

Pattern of LH secretion after repeated treatment with kisspeptin analog C6 reveals differential sensitivity between mice and ewes

C. Decourt , V. Robert , D. Lomet , Vincent Aucagne , G. Anderson
42. Colloque de la société de neuroendocrinologie (SNE 2017), Sep 2017, Dijon, France
Poster de conférence hal-02894288v1

Investigation of a kisspeptin analog effects both on synchronization of ovulation and puberty onset in domestic mammals and in rodents

Caroline Decourt , Vincent Robert , Didier Lomet , Vincent Aucagne , Greg Anderson
ReproSciences 2017, Apr 2017, Tours, France. 75 p., 2017, 2èmes Journées Scientifiques du GdR Repro
Poster de conférence hal-01603310v1

A new selective kisspeptin analog, C6, that advance puberty in mice and stimulate fertile ovulation in ewe

M. Beltramo , V. Robert , D. Lomet , K. Anger , M. Galibert
British Society for Neuroendocrinology Annual Meeting, Sep 2016, Glasgow, United Kingdom
Poster de conférence hal-02453336v1

Induction of fertile ovulation and puberty advancement by a new kisspeptin analog

Caroline Decourt , Vincent Robert , Didier Lomet , Karine Anger , M. Galibert
18th International Congress on Animal Reproduction (ICAR), Jun 2016, Tours, France. 676 p., 2016, 18th International Congress on Animal Reproduction (ICAR)
Poster de conférence hal-01604087v1

Induction of synchronized fertile ovulation by a new selective agonist of kisspeptin receptor

Caroline Decourt , Vincent Robert , Didier Lomet , Karine Anger , Mathieu Galibert
1 Journées du GdR 3606 Repro, Apr 2015, Rennes, France. 105 p., 2015, 1ères Journées Scientifiques du GdR Repro
Poster de conférence hal-02742326v1

Rational design of triazolo-lipopeptides analogs of kisspeptin inducing a long-lasting increase of gonadotropins

Vincent Aucagne , Vincent Robert , Mathieu Galibert , Jean-Baptiste Madinier , P. Marceau
24. Meeting of the American Peptide Society, Jun 2015, Orlando, United States. 2015, 24th Meeting of the American Peptide Society
Poster de conférence hal-02741835v1

Rational design of triazolo-lipopeptides analogs of kisspeptin inducing a long-lasting increase of gonadotrophins

Vincent Aucagne , Vincent Robert , Mathieu Galibert , Jean-Baptiste Madinier , P. Marceau
19. Congrès du Groupe Français des Peptides et des Protéines, May 2015, Port-Bail, United States. 2015
Poster de conférence hal-02793091v1

Development of new kisspeptin analogs to stimulate the reproductive system

Caroline Decourt , Karine Anger , Vincent Robert , Vincent Aucagne , Mathieu Galibert
International Conference on Gonadotropins & Receptors, Sep 2014, Tours, France. , 2014, ICGRIII International Conference on Gonadotropins & Receptors
Poster de conférence hal-02744014v1
Image document

Design and functional profiling of new KISS1R agonists

Massimiliano Beltramo , V. Aucagne , Vincent Robert , M. Galibert , J.B. Madinier
2. Annual Meeting of the GDR RCPG-PhysioMed, Oct 2013, Illkirch, France. 2013, 2nd Annual Meeting of the GDR RCPG-PhysioMed
Poster de conférence hal-02745908v1
Image document

La kisspeptine : une nouvelle voie pour maitriser l’ovulation chez les petits ruminants ?

Massimiliano Beltramo , V. Aucagne , R. Vincent , M. Galibert , J.B. Madinier
5. Journées d'Animation Scientifique du département Phase (JAS Phase 2013), Oct 2013, Paris, France. 2013
Poster de conférence hal-02805330v1