Vincent AUCAGNE

176
Documents

Présentation

EDUCATION

  • 1999-2002 - PhD in organic chemistry with higher honors, Université d'Orléans defended in 2003, grant from the French Ministry of Research and Technology

  • 1998-1999 -Master in chemistry and physicochemistry of bioactive compounds with higher honors, Universités Paris V, Paris XI and Orléans

PROFESSIONAL EXPERIENCES

  • 2006 - CNRS Research manager, Centre de Biophysique Moléculaire, Orléans - Team of Dr A. Delmas, Development of new tools for the solid-phase total synthesis of native or modified proteins and glycoproteins
  • 2004-2006 - Postdoctoral Research Associate, School of Chemistry, University of Edinburgh UK - Team of Prof. D. A. Leigh, Towards the total synthesis of the lasso peptide Microcin J25; Active template methodologies for the synthesis of mechanically-interlocked architectures
  • 2002-2003 - Fixed-term Lecturer in organic chemistry (ATER, one year fellowship) Université d'Orléans - Institut de Chimie Organique et Analytique (I.C.O.A.), Team of Prof. L. A. Agrofoglio, synthesis of new nucleoside analogues with antiviral activities
  • 1999-2002 - PhD in organic chemistry , I.C.O.A., team of Prof. P. Rollin Sulfur-containing phosphonium salts and anomeric Wittig reaction. Evaluation of vinylthio-functionalized alditols – new tools for stereocontrolled ring closure reactions
  • 1998-1998 - Postgraduate research fellow , I.C.O.A.; team of Prof. P. Rollin Synthesis of C-glycosidic analogues of glucosinolates

RESEARCH INTERESTS

  • Synthetic chemistry of biomacromolecules : Total synthesis of small proteins and glycoproteins. Click chemistry. Native chemical ligation Amino-acids, carbohydrates and nucleoside analogues. Modified or bioconjugated proteins. Synthetic vaccines. Drug-delivery.

  • Solid-phase organic synthesis : Solid-phase peptide and bio-macromolecule ligation. Solid-phase purification

  • Supramolecular Chemistry : Rotaxanes, Catenanes, Mechanically-interlocked architectures. Coordination chemistry

  • Thiochemistry : Thioester and thioacid peptides. Sulfonylated strained aminoacids. Sulfur as a tool in organic and bioorganic chemistry.

  • Referee for Letters in Organic Chemistry, the Journal of Organic Chemistry, the Journal of the American Chemical Society. Member of the French and American Chemical Societies

Publications

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Publications

Teichoic Acids Play a Key Role in the Antibacterial Activity of Big Defensins against Staphylococcus aureus

Noémie de San Nicolas , Albane Jouault , Aromal Asokan , Lhousseine Touqui , Imane El Fannassi et al.

ACS Infectious Diseases, 2025, 11 (12), pp.3542-3552. ⟨10.1021/acsinfecdis.5c00646⟩

Article dans une revue hal-05375669v1

The kisspeptin analog C6 reverses reproductive dysfunction in a mouse model of hyperprolactinemia

Chloe Beaudou , Louise Sionneau , Didier Lomet , Vincent Robert , Peggy Jarrier-Gaillard et al.

Reproduction [Cambridge], 2025, 169 (4), pp.e250036. ⟨10.1530/REP-25-0036⟩

Article dans une revue hal-05135772v1
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Molecular recognition of fungal methylated glucosylceramides by ETD151 defensin

Ons Kharrat , Françoise Paquet , Rouba Nasreddine , Jean-Baptiste Madinier , Reine Nehmé et al.

Journal of Biological Chemistry, 2025, 301 (9), pp.110587. ⟨10.1016/j.jbc.2025.110587⟩

Article dans une revue hal-05250295v1
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Identification, occurrence and prevention of aspartimide-related byproducts in chemical protein synthesis

El Hadji Cisse , Vincent Aucagne

Chemical Science, 2025, 16 (32), pp.14496 - 14508. ⟨10.1039/d5sc03824c⟩

Article dans une revue hal-05230442v1

The antimicrobial activity of ETD151 defensin is dictated by the presence of glycosphingolipids in the targeted organisms

Ons Kharrat , Yoshiki Yamaryo-Botté , Rouba Nasreddine , Sébastien Voisin , Thomas Aumer et al.

Proceedings of the National Academy of Sciences of the United States of America, 2025, 122 (7), pp.e2415524122. ⟨10.1073/pnas.2415524122⟩

Article dans une revue hal-05304638v1

Versatile fluorescent homobifunctional crosslinkers: expedient synthesis and application to di-affibody constructs for specific HER2+ cancer cell recognition

Eric Kaya , Fabienne Fasani , Carlo Pifferi , Catherine Grillon , Vincent Aucagne et al.

Bioorganic and Medicinal Chemistry, 2025, pp.118494. ⟨10.1016/j.bmc.2025.118494⟩

Article dans une revue hal-05376098v1

Strong impact of orally administered BCR4 defensin on aphid survival, embryo development, and symbiotic cells in three Acyrthosiphon pisum parthenogenetic lines

Hugo Terrasson , Karen Gaget , Garance Lapetoule , Isabelle Rahioui , François Renoz et al.

Journal of Pest Science, 2025, 98 (3), pp.1599-1612. ⟨10.1007/s10340-025-01923-0⟩

Article dans une revue hal-05127596v1
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Ubiquitylation of nucleic acids by DELTEX ubiquitin E3 ligase DTX3L

Kang Zhu , Chatrin Chatrin , Marcin J Suskiewicz , Vincent Aucagne , Benjamin Foster et al.

EMBO Reports, 2024, 25 (10), pp.4172-4189. ⟨10.1038/s44319-024-00235-1⟩

Article dans une revue hal-04739061v1
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An efficient site-selective, dual bioconjugation approach exploiting N-terminal cysteines as minimalistic handles to engineer tailored anti-HER2 affibody conjugates

Ana Novak , Florian Kersaudy , Sylvie Berger , Séverine Morisset-Lopez , François Lefoulon et al.

European Journal of Medicinal Chemistry, 2023, 260, pp.115747. ⟨10.1016/j.ejmech.2023.115747⟩

Article dans une revue hal-04222710v1

The Kisspeptin analogue C6 induces ovulation in jennies

Diana Fanelli , Massimiliano Beltramo , Giuseppe Conte , Benedetta Cerretini , Didier Lomet et al.

Theriogenology, 2022, 189, pp.107-112. ⟨10.1016/j.theriogenology.2022.06.014⟩

Article dans une revue hal-03746194v1
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DELTEX E3 ligases ubiquitylate ADP-ribosyl modification on protein substrates

Kang Zhu , Marcin Suskiewicz , Andrea Hloušek-Kasun , Hervé Meudal , Andreja Mikoč et al.

Science Advances , 2022, 8 (40), ⟨10.1126/sciadv.add4253⟩

Article dans une revue hal-03862525v1
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Treating mares with the long-acting kisspeptin analog C6 increases circulating gonadotropins but does not trigger ovulation

Flavie Derouin Tochon , Didier Lomet , Vincent Robert , Fabrice Reigner , Philippe Barrière et al.

Agriculture, 2022, 12 (11), pp.1846. ⟨10.3390/agriculture12111846⟩

Article dans une revue hal-03862471v1
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Functional Diversification of Oyster Big Defensins Generates Antimicrobial Specificity and Synergy against Members of the Microbiota

Noémie de San Nicolas , Aromal Asokan , Rafael D Rosa , Sébastien N Voisin , Marie-Agnès Travers et al.

Marine drugs, 2022, 20 (12), pp.745. ⟨10.3390/md20120745⟩

Article dans une revue hal-04246173v1
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Aphid BCR4 Structure and Activity Uncover a New Defensin Peptide Superfamily

Karine Loth , Nicolas Parisot , Françoise Paquet , Hugo Terrasson , Catherine Sivignon et al.

International Journal of Molecular Sciences, 2022, 23 (20), pp.12480. ⟨10.3390/ijms232012480⟩

Article dans une revue hal-03862651v1
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Real-Time Fluorescence Microscopy on Living E. coli Sheds New Light on the Antibacterial Effects of the King Penguin beta-Defensin AvBD103b

Céline Landon , Yanyu Zhu , Mainak Mustafi , Jean-Baptiste Madinier , Dominique Lelièvre et al.

International Journal of Molecular Sciences, 2022, This article belongs to the Special Issue Antimicrobial Peptides: Structure and Mechanism of Biological Activity, 23 (2057), pp.2057. ⟨10.3390/ijms23042057⟩

Article dans une revue hal-03860107v1
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Des protéines de synthèse taillées sur mesure pour investiguer le vivant

Vincent Aucagne , Fabienne Burlina , Oleg Melnyk , Vladimir Torbeev

L'Actualité Chimique, 2021, 468, pp.26-28

Article dans une revue hal-02959387v1
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Enzyme‐Cleavable Linkers for Protein Chemical Synthesis through Solid‐Phase Ligations

Skander A Abboud , Mehdi Amoura , J.B Madinier , Brigitte Renoux , Sébastien Papot et al.

Angewandte Chemie International Edition, 2021, 60 (34), pp.18612-18618. ⟨10.1002/anie.202103768⟩

Article dans une revue hal-03335485v1
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A straightforward methodology to overcome solubility challenges for N-terminal cysteinyl peptide segments used in native chemical ligation

Skander A Abboud , Hadji H. , Michel Doudeau , Hélène Bénédetti , Vincent Aucagne

Chemical Science, 2021, 12, pp.3194 - 3201. ⟨10.1039/d0sc06001a⟩

Article dans une revue hal-03447239v1
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Lanthanide DO3A-Complexes Bearing Peptide Substrates: The Effect of Peptidic Side Chains on Metal Coordination and Relaxivity

Sophie Laine , Jean-François Morfin , Mathieu Galibert , Vincent Aucagne , Celia ́ Bonnet et al.

Molecules, 2021, 26 (8), pp.2176. ⟨10.3390/molecules26082176⟩

Article dans une revue hal-03437152v1
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Monitoring Human Neutrophil Activation by a Proteinase 3 Near-Infrared Fluorescence Substrate-Based Probe

Ahlame Saidi , Mylène Wartenberg , J.B Madinier , Guy Ilango , Seda Seren et al.

Bioconjugate Chemistry, 2021, 32 (8), pp.1782-1790. ⟨10.1021/acs.bioconjchem.1c00267⟩

Article dans une revue hal-03525228v1
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An optimized protocol for the synthesis of N -2-hydroxybenzyl-cysteine peptide crypto-thioesters

Skander A. Abboud , Vincent Aucagne

Organic & Biomolecular Chemistry, 2020, 18 (40), pp.8199-8208. ⟨10.1039/d0ob01737j⟩

Article dans une revue hal-02975540v1
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Structure, function, and evolution of Gga -AvBD11, the archetype of the structural avian-double-β-defensin family

Nicolas Guyot , Herve Meudal , Sascha Trapp , Sophie Iochmann , Anne Silvestre et al.

Proceedings of the National Academy of Sciences of the United States of America, 2020, 117 (1), pp.337-345. ⟨10.1073/pnas.1912941117⟩

Article dans une revue hal-02522250v1
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Thiopurine Derivative-Induced Fpg/Nei DNA Glycosylase Inhibition: Structural, Dynamic and Functional Insights

Charlotte Rieux , Stéphane Goffinont , Franck Coste , Zahira Tber , Julien Cros et al.

International Journal of Molecular Sciences, 2020, 21 (6), pp.2058. ⟨10.3390/ijms21062058⟩

Article dans une revue hal-03082414v1
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Near-infrared emitting lanthanide(III) complexes as prototypes of optical imaging agents with peptide targeting ability: a methodological approach

Monika Cieslikiewicz-Bouet , Svetlana Eliseeva , Vincent Aucagne , A.F. Delmas , Isabelle Gillaizeau et al.

RSC Advances, 2019, 9 (3), pp.1747-1751. ⟨10.1039/c8ra09419e⟩

Article dans une revue hal-02064990v1
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The Ancestral N-Terminal Domain of Big Defensins Drives Bacterially Triggered Assembly into Antimicrobial Nanonets

Karine Loth , Agnès Vergnes , Cairé Barreto , Sébastien N Voisin , Hervé Meudal et al.

mBio, 2019, 10 (5), pii: e01821-19. ⟨10.1128/mBio.01821-19⟩

Article dans une revue hal-02328576v1

Acute and subacute effects of a synthetic kisspeptin analog, C6, on serum concentrations of luteinizing hormone, follicle stimulating hormone, and testosterone in prepubertal bull calves

P.A. Parker , E.A. Coffman , K.G. Pohler , J.A. Daniel , V. Aucagne et al.

Theriogenology, 2019, 130, pp.111-119. ⟨10.1016/j.theriogenology.2019.03.002⟩

Article dans une revue hal-02088608v1
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The kisspeptin analog C6 is a possible alternative to PMSG (pregnant mare serum gonadotropin) for triggering synchronized and fertile ovulations in the Alpine goat

Caroline Decourt , Vincent Robert , Didier Lomet , Karine Anger , Marion Georgelin et al.

PLoS ONE, 2019, 14 (3), pp.e0214424. ⟨10.1371/journal.pone.0214424⟩

Article dans une revue hal-02088631v1
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In silico peptide ligation: Iterative Residue Docking and Linking as a new approach to predict protein-peptide interactions

Julien Diharce , Mickaël Cueto , Massimiliano Beltramo , Vincent Aucagne , Pascal Bonnet

Molecules, 2019, 24 (7), pp.1-14. ⟨10.3390/molecules24071351⟩

Article dans une revue hal-03525312v1
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Imaging of extracellular cathepsin S activity by a selective near infrared fluorescence substrate-based probe

Mylène Wartenberg , Ahlame Saidi , Mathieu Galibert , Alix Joulin-Giet , Julien Burlaud-Gaillard et al.

Biochimie, 2019, 166, pp.84-93. ⟨10.1016/j.biochi.2019.03.013⟩

Article dans une revue hal-02088627v1
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Synthesis of aryl-thioglycopeptides through chemoselective Pd-Mediated conjugation

David Montoir , Mehdi Amora , Zine El Abidine Aabasa , Thimmalapura Marulappa Vishwanatha , Expédite Yen-Pon et al.

Chemical Science, 2018, 9 (46), pp.8753-8759. ⟨10.1039/C8SC02370K⟩

Article dans une revue hal-02622102v1

Substrate-derived triazolo- and azapeptides as inhibitors of cathepsins K and S

Matthieu Galibert , Mylène Wartenberg , Fabien Lecaille , Ahlame Saidi , Sylvie Mavel et al.

European Journal of Medicinal Chemistry, 2018, 144, pp.201 - 210. ⟨10.1016/j.ejmech.2017.12.012⟩

Article dans une revue hal-01702303v1

Spermaurin, an La1-like peptide from the venom of the scorpion Scorpio maurus palmatus , improves sperm motility and fertilization in different mammalian species

Guillaume Martinez , Jean-Pascal Hograindleur , Sébastien Voisin , Roland Abi Nahed , Tarek M. Abd El Aziz et al.

Molecular Human Reproduction, 2017, 23 (2), pp.116-131. ⟨10.1093/molehr/gaw075⟩

Article dans une revue hal-01618630v1

Efficient synthesis of cysteine-rich cyclic peptides through intramolecular native chemical ligation of N-Hnb-Cys peptide crypto-thioesters

Victor Terrier , Agnès F. Delmas , Vincent Aucagne

Organic & Biomolecular Chemistry, 2017, 15 (2), pp.316 - 319. ⟨10.1039/c6ob02546c⟩

Article dans une revue hal-01618781v1

A straightforward method for automated Fmoc-based synthesis of bio-inspired peptide crypto-thioesters

Victor P. Terrier , Hélène Adihou , Mathieu Arnould , Agnès F. Delmas , Vincent Aucagne

Chemical Science, 2016, 7 (1), pp.339 - 345. ⟨10.1039/C5SC02630J⟩

Article dans une revue hal-01407765v1

A Helping Hand to Overcome Solubility Challenges in Chemical Protein Synthesis

Michael T. Jacobsen , Mark E. Petersen , Xiang Ye , Mathieu Galibert , George H. Lorimer et al.

Journal of the American Chemical Society, 2016, 138 (36), pp.11775 - 11782. ⟨10.1021/jacs.6b05719⟩

Article dans une revue hal-01407028v1
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A synthetic kisspeptin analog that triggers ovulation and advances puberty

Caroline Decourt , Vincent Robert , Karine Anger , Mathieu Galibert , Jean-Baptiste Madinier et al.

Scientific Reports, 2016, 6 (1), pp.26908. ⟨10.1038/srep26908⟩

Article dans une revue hal-01406943v1

Native Chemical Ligation Strategy to Overcome Side Reactions during Fmoc-Based Synthesis of C-Terminal Cysteine-Containing Peptides

Dominique Lelièvre , Victor P. Terrier , Agnès F. Delmas , Vincent Aucagne

Organic Letters, 2016, 18 (5), pp.920 - 923. ⟨10.1021/acs.orglett.5b03612⟩

Article dans une revue hal-01407492v1

Activation of TRPV2 and BKCa channels by the LL-37 enantiomers stimulates calcium entry and migration of cancer cells.

Audrey Gambade , Sami Zreika , Maxime Guéguinou , Igor Chourpa , Gaëlle Fromont et al.

Oncotarget, 2016, 7 (17), pp.23785-23800. ⟨10.18632/oncotarget.8122⟩

Article dans une revue hal-01387061v1

Complete 1H, 15N and 13C assignment of trappin-2 and 1H assignment of its two domains, elafin and cementoin

Karine Loth , Soha Abou Ibrahim Alami , Chahrazed Habès , Solène Garrido , Vincent Aucagne et al.

Biomolecular NMR Assignments, 2016, 10 (1), pp.223 - 226. ⟨10.1007/s12104-016-9671-1⟩

Article dans une revue hal-01407495v1

Combining triazole ligation and enzymatic glycosylation on solid phase simplifies the synthesis of very long glycoprotein analogues

Mathieu Galibert , Véronique Piller , Friedrich Piller , Vincent Aucagne , Agnès F. Delmas

Chemical Science, 2015, 6 (6), pp.3617-3623. ⟨10.1039/C5SC00773A⟩

Article dans une revue hal-01178852v1

Rational Design of Triazololipopeptides Analogs of Kisspeptin Inducing a Long-Lasting Increase of Gonadotropins

Massimiliano Beltramo , Vincent Robert , Mathieu Galibert , Jean-Baptiste Madinier , Philippe Marceau et al.

Journal of Medicinal Chemistry, 2015, 58 (8), pp.3459-3470. ⟨10.1021/jm5019675⟩

Article dans une revue hal-01170460v1
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A mechanically interlocked molecular system programmed for the delivery of an anticancer drug

Romain Barat , Thibaut Legigan , I. Tranoy-Opalinski , Brigitte Renoux , Elodie Peraudeau et al.

Chemical Science, 2015, 6 (4), pp.2608-2613. ⟨10.1039/c5sc00648a⟩

Article dans une revue hal-03127729v1

Solid phase oxime ligations for the iterative synthesis of polypeptide conjugates

Isidore E. Decostaire , Dominique Lelièvre , Vincent Aucagne , Agnès F. Delmas

Organic & Biomolecular Chemistry, 2014, 12 (29), pp.5536-5543. ⟨10.1039/c4ob00760c⟩

Article dans une revue hal-01178857v1

The nuclear magnetic resonance solution structure of the synthetic AhPDF1.1b plant defensin evidences the structural feature within the γ-motif

Fanny Meindre , Dominique Lelièvre , Karine Loth , Oriane Mith , Vincent Aucagne et al.

Biochemistry, 2014, 53 (49), pp.7745-54. ⟨10.1021/bi501285k⟩

Article dans une revue hal-01118914v1
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Highly efficient solid phase synthesis of large polypeptides by iterative ligations of bis(2-sulfanylethyl)amido (SEA) peptide segments

Laurent Raibaut , Hélène Adihou , Rémi Desmet , Agnès F. Delmas , Vincent Aucagne et al.

Chemical Science, 2013, 4, pp.4061-4066. ⟨10.1039/c3sc51824h⟩

Article dans une revue hal-00944814v2

Synthesis of a biologically active triazole-containing analogue of cystatin A through successive peptidomimetic alkyne-azide ligations.

Ibai E Valverde , Fabien Lecaille , Gilles Lalmanach , Vincent Aucagne , Agnès F Delmas

Angewandte Chemie International Edition, 2012, 51 (3), pp.718-22. ⟨10.1002/anie.201107222⟩

Article dans une revue istex hal-00726293v1
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Initial insights into structure-activity relationships of avian defensins.

Chrystelle Derache , Hervé Meudal , Vincent Aucagne , Kevin J Mark , Martine Cadène et al.

Journal of Biological Chemistry, 2012, 287 (10), pp.7746-55. ⟨10.1074/jbc.M111.312108⟩

Article dans une revue hal-00721842v1

A water soluble Cu-I-NHC for CuAAC ligation of unprotected peptides under open air conditions.

Christelle Gaulier , Audrey Hospital , Bertrand Legeret , Delmas A.F. , Vincent Aucagne et al.

Chemical Communications, 2012, 48, pp.4005-4007

Article dans une revue hal-00711780v1

Second generation specific-enzyme-activated rotaxane propeptides.

Antony Fernandes , Aurélien Viterisi , Vincent Aucagne , David A Leigh , Sébastien Papot

Chemical Communications, 2012, 48 (15), pp.2083-5. ⟨10.1039/c2cc17458h⟩

Article dans une revue hal-00678757v1

Towards the simplification of protein synthesis: iterative solid-supported ligations with concomitant purifications.

Vincent Aucagne , Ibai E Valverde , Philippe Marceau , Mathieu Galibert , Nabil Dendane et al.

Angewandte Chemie International Edition, 2012, 51 (45), pp.11320-4. ⟨10.1002/anie.201206428⟩

Article dans une revue istex hal-00748170v1

Sulfur-containing amide-based [2]rotaxanes and molecular shuttles

Andrea Altieri , Vincent Aucagne , Romen Carrillo , Guy Clarkson , Daniel d'Souza et al.

Chemical Science, 2011, 2 (10), pp.1922. ⟨10.1039/C1SC00335F⟩

Article dans une revue hal-02088663v1

Primary Structure and Antibacterial Activity of Chicken Bone Marrow-Derived beta-Defensins

Chrystelle Derache , Valérie Labas , Vincent Aucagne , Hervé Meudal , Céline Landon et al.

Antimicrobial Agents and Chemotherapy, 2009, 53 (11), pp.4647-4655. ⟨10.1128/AAC.00301-09⟩

Article dans une revue hal-00522326v1

Click a la carte: robust semi-orthogonal alkyne protecting groups for multiple successive azide/alkyne cycloadditions

Ibai E. Valverde , Agnès F. Delmas , Vincent Aucagne

Tetrahedron, 2009, 65 (36), pp.7597-7602. ⟨10.1016/j.tet.2009.06.093⟩

Article dans une revue istex hal-00525398v1

Rotaxane-based propeptides: protection and enzymatic release of a bioactive pentapeptide.

Anthony Fernandes , Aurélien Viterisi , Frédéric Coutrot , Stéphanie Potok , David A. Leigh et al.

Angewandte Chemie International Edition, 2009, 48 (35), pp.6443-7. ⟨10.1002/anie.200903215⟩

Article dans une revue hal-00467015v1

Thermodynamics versus kinetics in hetero-Michael cyclizations: a highly stereoselective approach to access both epimers of a C-D-mannopyranoside

Vincent Aucagne , A. Tatibouët , Patrick Rollin

Tetrahedron Letters, 2008, 49, pp.4750-4753. ⟨10.1016/j.tetlet.2008.05.117⟩

Article dans une revue istex hal-00512453v1

Preparation of peptide thioesters using Fmoc strategy through hydroxyl side chain anchoring

Dominique Lelièvre , P. Barta , Vincent Aucagne , A.F. Delmas

Tetrahedron Letters, 2008, 49 (25), pp.4016-4019. ⟨10.1016/j.tetlet.2008.04.087⟩

Article dans une revue istex hal-00518141v1

Alkyne-Azide Click Chemistry Mediated Carbanucleosides Synthesis

Julie Broggi , Nicolas Joubert , Vincent Aucagne , Sabine Berteina-Raboin , S. Diez-Gonzalez et al.

Nucleosides, Nucleotides and Nucleic Acids, 2007, 26 (10-12), pp.1391-1394. ⟨10.1080/15257770701534139⟩

Article dans une revue hal-02086003v1

Study of different copper(I) catalysts for the "click chemistry" approach to carbanucleosides

J. Broggi , N. Joubert , Vincent Aucagne , T. Zevaco , S. Berteina-Raboin et al.

Nucleosides, Nucleotides and Nucleic Acids, 2007, 26, pp.779-783

Article dans une revue hal-00275217v1

Synergic effect of hydride and proton donors in the Pd(0)-mediated deprotection of Nα-Aloc proline derivatives

Isidore P. Decostaire , Dominique Lelièvre , Vincent Aucagne , Agnès F. Delmas

Tetrahedron Letters, 2007, 48, pp.6523-6526. ⟨10.1016/j.tetlet.2007.07.061⟩

Article dans une revue istex hal-00166600v1

Catalytic "Active-Metal" template synthesis of [2]rotaxanes, [3]rotaxanes, and molecular shuttles, and some observations on the mechanism of the Cu(I)-catalyzed azide-alkyne 1,3-cycloaddition

Vincent Aucagne , J. Berna , Jd Crowley , Sm Goldup , Kd Haenni et al.

Journal of the American Chemical Society, 2007, 129, pp.11950-11963

Article dans une revue hal-00275210v1

Catalytic “Click” Rotaxanes: A Substoichiometric Metal-Template Pathway to Mechanically Interlocked Architectures

Vincent Aucagne , Kevin Hänni , David Leigh , Paul Lusby , D Barney Walker

Journal of the American Chemical Society, 2006, 128 (7), pp.2186-2187. ⟨10.1021/ja056903f⟩

Article dans une revue istex hal-02086010v1

Chemoselective formation of successive triazole linkages in one pot: "click-click" chemistry

Vincent Aucagne , David A. Leigh

Organic Letters, 2006, 8 (20), pp.4505-4507. ⟨10.1021/ol061657d⟩

Article dans une revue hal-00387909v1

Rotaxanes of Cyclic Peptides

Vincent Aucagne , David Leigh , Julia Lock , Andrew Thomson

Journal of the American Chemical Society, 2006, 128 (6), pp.1784-1785. ⟨10.1021/ja057206q⟩

Article dans une revue istex hal-02086005v1

Synthesis and antiviral activity of novel acyclic nucleosides in the 5-alkynyl- and 6-alkylfuro[2,3-d]pyrimidine series

Franck Amblard , Vincent Aucagne , Pierre Guenot , Raymond Schinazi , Luigi Agrofoglio

Bioorganic and Medicinal Chemistry, 2005, 13 (4), pp.1239-1248. ⟨10.1016/j.bmc.2004.11.057⟩

Article dans une revue istex hal-02086014v1

Synthesis of 5-haloethynyl- and 5-(1,2-dihalo)vinyluracil nucleosides: Antiviral activity and cellular toxicity

Vanessa Escuret , Vincent Aucagne , Nicolas Joubert , David Durantel , Kimberly Rapp et al.

Bioorganic and Medicinal Chemistry, 2005, 13 (21), pp.6015-6024. ⟨10.1016/j.bmc.2005.06.021⟩

Article dans une revue istex hal-02086013v1

Regioselective Michael-induced cyclisation of γ- and δ-hydroxy vinyl sulfides and vinyl dithiocarbamates

V. Aucagne , C. Lorin , A. Tatibouët , P. Rollin

Tetrahedron Letters, 2005, 46 (25), pp.4349-4352. ⟨10.1016/j.tetlet.2005.04.112⟩

Article dans une revue istex hal-02086017v1

Highly Efficient AgNO3-Catalyzed Preparation of Substituted Furanopyrimidine Nucleosides [cf. (III)].

Vincent Aucagne , Franck Amblard , Luigi Agrofoglio

ChemInform, 2005, 36 (18), ⟨10.1002/chin.200518181⟩

Article dans une revue istex hal-02086027v1

Palladium-Catalyzed Synthesis of Uridines on Polystyrene-Based Solid Supports

Vincent Aucagne , Sabine Berteina-Raboin , Pierre Guenot , Luigi Agrofoglio

Journal of Combinatorial Chemistry, 2004, 6 (5), pp.717-723. ⟨10.1021/cc049976o⟩

Article dans une revue hal-02086022v1

Wittig approach to carbohydrate-derived vinyl sulfides, new substrates for regiocontrolled ring-closure reactions

Vincent Aucagne , Arnaud Tatibouët , Patrick Rollin

Tetrahedron, 2004, 60 (8), pp.1817-1826. ⟨10.1016/j.tet.2003.12.040⟩

Article dans une revue istex hal-02086021v1

Straightforward Synthesis of Labeled and Unlabeled Pyrimidine d4Ns via 2′,3′-Diyne seco Analogues through Olefin Metathesis Reactions

Isabelle Gillaizeau , Irene m. Lagoja , Steve p. Nolan , Vincent Aucagne , Jef Rozenski et al.

European Journal of Organic Chemistry, 2003, 2003 (4), pp.666-671. ⟨10.1002/ejoc.200390107⟩

Article dans une revue istex hal-02086029v1

Sulfenic acids in the carbohydrate field. Synthesis of transient glycosulfenic acids and their addition to unsaturated acceptors.

Vincent Aucagne , Maria Aversa , Anna Barattucci , Paola Bonaccorsi , Placido Giannetto et al.

Journal of Organic Chemistry, 2002, 67 (20), pp.6925-30

Article dans une revue hal-02086034v1

Synthetic Approaches to C-Glucosinolates

Vincent Aucagne , David Gueyrard , Arnaud Tatibouët , Alain Quinsac , Patrick Rollin

Tetrahedron, 2000, 56 (17), pp.2647-2654. ⟨10.1016/S0040-4020(00)00153-8⟩

Article dans une revue istex hal-02086037v1

the first synthesis of c-glucotropeolin

V. Aucagne , D. Gueyrard , A. Tatibout , S. Cottaz , H. Driguez et al.

Tetrahedron Letters, 1999, pp.7319-7321

Article dans une revue hal-00309763v1

Palladium-mediated S-arylation and S-allylation for late-stage peptide functionalisation and protein conjugation

Ross Ballantine , Ameni Hadj Mohamed , Mingxiang Zhu , Aromal Asokan , Linhua Shen et al.

37. European Peptide Symposium. 14. International Peptide Symposium, Aug 2024, Florence, Italy. pp.692-P2.010

Communication dans un congrès hal-05075799v1

Big-Defensin Diversification in Oysters: Implications for Host Defense and Microbiota Management (D. Destoumieux-Garzon INVITED SPEAKER)

Noémie de San Nicolas , A. Jouault , Aromal Asokan , Lhousseine Touqui , K Loth et al.

IMAP 2024 International Meeting on Antimicrobial Peptides, Sep 2024, Londres, United Kingdom

Communication dans un congrès hal-04882843v1

Big defensins: A Diversified Family of Antimicrobial Peptides Confronting Versatile Microbial Environments (DELPHINE DESTOUMIEUX-GARZON INVITED SPEAKER)

Noémie de San Nicolas , Aromal Asokan , Rafaela da Rosa , Vincent Aucagne , K. Loth et al.

Antimicrobial Peptides. Yesterday, Today, and Tomorrow, Oct 2023, Omaha, Nebraska, USA, United States

Communication dans un congrès hal-04885227v1

Bacteriocyte-specific Cysteine-Rich (BCR) peptides form a new aphid-specific defensin-like family and are promising regulators of aphid symbiosis

Hugo Terrasson , Karine Loth , Nicolas Parisot , Françoise Paquet , Isabelle Rahioui et al.

Rencontres du Réseau Ecologie des Interactions Durables (REID), May 2023, Poitiers, France

Communication dans un congrès hal-04633283v1

Les peptides « Bacteriocyte-specific Cystein-Rich » : une nouvelle famille de défensine. Régulateurs de la symbiose chez les pucerons ?

Hugo Terrasson , Karine Loth , Nicolas Parisot , Françoise Paquet , Isabelle Rahioui et al.

9ème Journées du GDR "MultiFonction des Peptides AntiMicrobiens" (MuFoPAM), Oct 2022, Amboise, France

Communication dans un congrès hal-04633233v1

Enabling the synthesis of hydrophobic proteins using NCL-labile solubilizing tags: a case study of Crassostrea gigas big defensin 3

A. Asokan , Noémie de San Nicolas , H. Meudal , K. Loth , Delphine Destoumieux-Garzon et al.

22nd GFPP & 5th BPGM French-Belgian Joint Meeting, Groupe Français des Peptides et Protéines, May 2022, Port Leucate, France

Communication dans un congrès hal-03976595v1

Peptides « Bacteriocyte-specific Cysteine Rich » (BCR) : un rôle dans le contrôle de la symbiose ? Focus sur BCR4 chez le puceron du pois.

Hugo Terrasson , Karine Loth , Nicolas Parisot , Françoise Paquet , Isabelle Rahioui et al.

12èmes rencontres du réseau français de Biologie Adaptative des Pucerons et Organismes Associés (BAPOA), May 2022, Nice, France

Communication dans un congrès hal-04771966v1

Functional DIversification of Big-Defensins and the shaping of oyster microbiota

Noémie de San Nicolas , A. Asokan , R.D. Rosa , S.N. Voisin , Marie Agnès Travers et al.

AMP 2022 7th International Symposium on Antimicrobial Peptides, Nov 2022, Paris, France

Communication dans un congrès hal-03976756v1

Développements méthodologiques pour la synthèse chimique de protéines

Vincent Aucagne

33e colloque Biotechnocentre, Oct 2021, Chaumont-sur-Tharonne, France

Communication dans un congrès hal-03563421v1

Determination of Binding Affinities with Flow-Induced Dispersion Analysis: The Case of Synthetic Affibodies

Josef Hamacek , Edina Numanovic , Vincent Aucagne

NECTAR, annual meeting, Aug 2021, Lisbon, Portugal

Communication dans un congrès hal-03482197v1

A chemical toolbox for simplifying chemical protein synthesis

Vincent Aucagne

Congrès annuel de la Société Française de Biochimie et Biologie Moléculaire (SFBBM21), Jul 2021, Paris, France

Communication dans un congrès hal-03563426v1

Synthesis of aryl-thioglycopeptides through chemoselective Pd-mediated conjugation

David Montoir , Mehdi Amoura , Zine El Abidine Ababsa , T.M. Vishwanatha , Expédite Yen-Pon et al.

4. GFPP Chemical Ligation Meeting (Ligation2020), Jan 2020, Orléans, France

Communication dans un congrès hal-02892772v1

Exploring ancestral traits lost during molecular evolution of Big-Defensins Towards β-defensins (DELPHINE DESTOUMIEUX-GARZON, INVITED SPEAKER)

K Loth , Agnès Vergnes , C Barreto , S Voisin , H. Meudal et al.

Gordon Research Conference "Antimicrobial Peptides", Feb 2019, Barga, Italy

Communication dans un congrès hal-04891216v1

”Tag and modify” strategy for the Pd-catalyzed Thioglycoconjugation of peptides

D. Montoir , Mehdi Amoura , A. Ababsa Z. E. , M. Vishwanatha T. , E. Yen-Pon et al.

Noncanonical amino acids (ncAAs): Tools for biological and biophysical investigations, Oct 2019, Paris, France

Communication dans un congrès hal-02892775v1

Gga-AvBD11, the archetype of a new structural family of defensins

H. Meudal , Nicolas Guyot , K. Loth , G. Jousset , S. Trapp et al.

21e réunion du Groupe Français des Peptides et des Protéines (GFPP21), May 2019, Amboise, France

Communication dans un congrès hal-02892790v1

Design of both pseudopeptide inhibitors and imaging probes derived from a unique substrate sequence: a versatile molecular toolbox for studying proteases

G. Lalmanach , M. Wartenberg , M. Galibert , A. Saidi , F. Lecaille et al.

21e réunion du Groupe Français des Peptides et des Protéines (GFPP21), May 2019, Amboise, France

Communication dans un congrès hal-02892793v1

Développement de bras enzymo-labiles pour la synthèse totale de protéines par ligations chimiques sur support solide

S. Abboud , V. Piller , S. Papot , V. Aucagne

32e Colloque Biotechnocentre, Oct 2019, Seillac, France

Communication dans un congrès hal-02893386v1

Séminaire invité : Development of a molecular toolbox to simplify the chemical synthesis of proteins

Vincent Aucagne

Institut de Chimie des Substances Naturelles, Mar 2019, Gif-sur-Yvette, France

Communication dans un congrès hal-02974369v1

An improved synthesis of N-Hnb-Cys peptide crypto-thioesters ‒studies on the epimerization of cysteine during solid-phase reductive amination

S. Abboud , Mehdi Amoura , V. P. Terrier , A. F. Delmas , V. Aucagne

21e réunion du Groupe Français des Peptides et des Protéines (GFPP21), May 2019, Amboise, France

Communication dans un congrès hal-02892784v1

Fragment covalent docking (FCD) approach: An innovative in silico tools for the prediction of peptide-protein interaction

Julien Diharce , Mickaël Cueto , Vincent Aucagne , Massimiliano Beltramo , Pascal Bonnet

256th National Meeting and Exposition of the American-Chemical-Society Nanoscience, Nanotechnology and Beyond (ACS), American Chemical Society (ACS). USA., Aug 2018, Boston, United States. pp.2

Communication dans un congrès hal-02734800v1

Rational design of kisspeptin analogs for the control of reproduction

T.M. Vishwanatha , C. Decourt , V.P. Terrier , V. Robert , M. Galibert et al.

4th Belgian Peptide Group Meeting, Feb 2018, Bruxelles, Belgium

Communication dans un congrès hal-02892809v1

Synthesis and structural characterization of naturally-occuring disulfide rich antimicrobial peptides Gyros Protein Technologies

A.F. Delmas , Vincent Aucagne

European peptide symposium, Aug 2018, Dublin, Ireland

Communication dans un congrès hal-02919154v1

Séminaire invité : Développement d’une boîte à outils pour simplifier la synthèse chimique de protéines

Vincent Aucagne

Institut des Biomolécules Max Mousseron, Nov 2018, Montpellier, France

Communication dans un congrès hal-02974372v1

N-2-hydroxybenzyl-cysteine peptide crypto-thioesters for native chemical ligation

Mehdi Amoura , D. Sarraf , L. Nauton , V.P. Terrier , D. Lelièvre et al.

35th European Peptide Symposium (EPS35), Aug 2018, Dublin, Ireland

Communication dans un congrès hal-02892802v1

1ère structure 3D d’une défensine à double motif β-défensine, Gga-AvBD11 du poulet Gallus gallus, et explorations fonctionnelles

Nicolas Guyot , Hervé Meudal , Karine Loth , Guillaume Jousset , Anne Silvestre et al.

5es Journées GDR MuFoPAM, Centre National de la Recherche Scientifique (CNRS). FRA., Oct 2018, Paris, France

Communication dans un congrès hal-02788993v1

Séminaire invité : Développement d'une boîte à outils pour simplifier la synthèse chimique de protéines

Vincent Aucagne

Laboratoire BioCIS - Biomolécules : Conception, Isolement et Synthèse, Université Paris-Sud, Apr 2017, Châtenay-Malabry, France

Communication dans un congrès hal-02974390v1

Séminaire invité : Development of a molecular toolbox to simplify the chemical synthesis of proteins and constrained peptides natural products

Vincent Aucagne

Institut Européen de Chimie et Biologie, Apr 2017, Bordeaux, France

Communication dans un congrès hal-02974400v1

Séminaire invité : Triazolopeptides as proteolysis-resistant, highly potent KISS1R agonists

Vincent Aucagne

Universiteit Gent, May 2017, Gand, Belgium

Communication dans un congrès hal-02974376v1

Simplifier la synthèse totale de protéines et de mini-protéines riches en pont disulfures

Vincent Aucagne

7e Symposium Francophone de Synthèse Totale (SFST7), Jun 2017, Orsay, France

Communication dans un congrès hal-02892762v1

A non-chromatographic catch-and-release purification method to simplify the synthesis of cysteine-rich peptides

A. Casas-Mora , M. Galibert , A.F. Delmas , V. Aucagne

20e réunion du Groupe Français des Peptides et des Protéines (GFPP 20), Mar 2017, Arcachon, France

Communication dans un congrès hal-02893392v1

Séminaire invité : Development of a molecular toolbox to simplify the chemical synthesis of proteins and constrained peptides natural products

Vincent Aucagne

Vrije Universiteit Brussel, May 2017, Bruxelles, Belgium

Communication dans un congrès hal-02974374v1

Native Chemical ligation simplifies the access of multidomain antimicrobial peptides: application to the study of big-defensins

A.F. Delmas , V.P. Terrier , R.D. Rosa , A. Bressan , P. Marceau et al.

International symposium on AntiMicrobial Peptides (AMP2016), Jun 2016, Montpellier, France

Communication dans un congrès hal-02892834v1

Séminaire invité : Development of a molecular toolbox to simplify the chemical synthesis of proteins.

Vincent Aucagne

Institut Curie, Jun 2016, Paris, France

Communication dans un congrès hal-02974405v1

Séminaire invité : A molecular toolbox for exploring new chemical spaces: making simpler the synthesis of biologically- and therapeutically-relevant small proteins and complex peptides

Vincent Aucagne

Sanofi, Sep 2016, Francfort, Germany

Communication dans un congrès hal-02974403v1

New KISS1R agonists with potential for the treatment of reproductive disorder

Massimiliano Beltramo , Vincent Aucagne , Vincent Robert , Mathieu Galibert , Jean-Baptiste Madinier et al.

11. International Symposium on GnRH: The hypothalamic-pituitary-gonadal axis in cancer and reproduction, Kenes International. USA., Feb 2014, Salzburg, Austria

Communication dans un congrès hal-02742248v1

Design and profiling of new selective KISS1R agonists that stimulate the reproductive system

Massimiliano Beltramo , Vincent Aucagne , Vincent Robert , Mathieu Galibert , Jean-Baptiste Madinier et al.

8. International Congress of Neuroendocrinology, Society for Behavioral Neuroendocrinology (SBN). USA., Aug 2014, Sydney, Australia

Communication dans un congrès hal-02738894v1

First insights into the structure-activity relationships of avian beta-defensins.

Chrystelle Derache , Hervé Meudal , Vincent Aucagne , Martine Cadène , Agnès Delmas et al.

2nd International Symposium on Antimicrobial Peptides - Food Veterinary Medical and Novel Applications., 2009, Saint-Malo, France

Communication dans un congrès hal-02753345v1

Avian beta-defensins in the control of bacterial pathogens of chicken digestive tract

Anne-Christine Lalmanach , Chrystelle Derache , Evelyne Esnault , Valérie Labas , V. Aucagne et al.

2. International Symposium on Antimicrobial Peptides. Food Veterinary Medical and Novel Applications, Jun 2009, Saint-Malo, France

Communication dans un congrès hal-02751627v1

PA1b, un peptide à activité insecticide : relations structure/fonction

P. da Silva , I. Rahioui , C. Laugier , Yvan Rahbé , A. Delmas et al.

XVème Colloque de Physiologie de l'Insecte, 2007, Rennes (France), juillet 2007, France. pp.1-1

Communication dans un congrès hal-00391295v1
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A semi-synthetic pathway to SUMOylated protein mimics

El Hadji Cisse , Pierre Prieu-Serandon , Marcin J Suskiewicz , Vincent Aucagne

EMBO Workshop: Ubiquitin and ubiquitin-like proteins in health and disease, Sep 2024, Cavtat & Dubrovnik, Croatia

Poster de conférence hal-05217596v1

The aphid BCR4 structure and activity uncover a new defensin peptide superfamily

Hugo Terrasson , Karine Loth , Nicolas Parisot , Françoise Paquet , Isabelle Rahioui et al.

XXVII International Congress of Entomology, Aug 2024, Kyoto, Japan

Poster de conférence hal-04702878v1

The Bacteriocyte-specific Cysteine-Rich (BCR) proteins: a role in the control of aphid symbiosis ?

Hugo Terrasson , Karine Loth , Françoise Paquet , Nicolas Parisot , Isabelle Rahioui et al.

Journée scientifique enjeu « santé globale et bio‐ingénierie » de l'INSA Lyon, Apr 2023, Villeurbanne, France

Poster de conférence hal-04633269v1

Bacteriocyte specific Cystein Rich peptides, a new defensin like protein family , are promising regulators of aphid symbiosis

Hugo Terrasson , Karine Loth , Nicolas Parisot , Françoise Paquet , Isabelle Rahioui et al.

10th congress of the International Symbiosis Society (ISS) - 3rd International Conference on Holobionts (joint meeting), Jul 2022, Lyon, France

Poster de conférence hal-04771990v1

Role of big-defensins in the control of oyster microbiota

Noémie de San Nicolas , A Asokan , S Voisin , A Delmas , Vincent Aucagne et al.

8ème journées du GDR MuFoPAM, Oct 2021, Marseille, France.

Poster de conférence hal-04888804v1

Synthesis of N-Hnb-Cys peptide crypto-thioesters: identification of imadozolidinone and epimerized side products, and development of an optimized protocol

S. Abboud , A.F. Delmas , V. Aucagne

4th GFPP Chemical Ligation Meeting (Ligation2020), Jan 2020, Orléans, France

Poster de conférence hal-02893398v1

Synthesis of aryl-thioglycopeptides through chemoselective Pd-catalyzed conjugation

T.M. Vishwanatha , D. Montoir , Mehdi Amoura , Z. El Ababsa , E. Yen-Pon et al.

26. American Peptide Symposium (APS 2019), Jun 2019, Monterey, Californie, United States

Poster de conférence hal-02893419v1

Spermaurin, a scorpion venom disulfide-rich miniprotein that improves sperm motility and fertilization in mammals.

Françoise Paquet , K. Loth , C. Arnoult , V. Aucagne , A.F. Delmas

21e réunion du Groupe Français des Peptides et des Protéines (GFPP21), May 2019, Amboise, France

Poster de conférence hal-02893462v1

Incorporation of trifluoromethylated pseudoproline in an entomotoxic knottin: effects on oxidative folding, 3D structure and biological activity

F. Coste , G. Chaume , J.-B. Madinier , I. Rahioui , B. Castaing et al.

21e congrès du Groupe Français des Peptides et des Protéines (GFPP), May 2019, Amboise, France

Poster de conférence hal-02893471v1

A new structural family for antimicrobial defensins

H. Meudal , K. Loth , G. Jousset , V. Aucagne , Nicolas Guyot et al.

NMR : a tool for biology XIth, Jan 2019, Paris, France

Poster de conférence hal-02919171v1
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Design of GPR54 (Kiss1r) crosslinker peptides: new tools to study G protein-coupled receptors (GPCR) localization and function

Vincent Robert , Vishwanatha Thimmalapura Marulappa , Didier Lomet , Caroline Decourt , Laia Miret et al.

SNE, Oct 2019, Tours, France

Poster de conférence hal-03381932v1

N-Hnb-Cys peptide crypto-thioesters: optimized synthetic protocol and second generation device

S. Abboud , Mehdi Amoura , P. Terrier V. , A.F. Delmas , V. Aucagne

Noncanonical amino acids (ncAAs): Tools for biological and biophysical investigations, Oct 2019, Paris, France

Poster de conférence hal-02893409v1

Chemical synthesis and natural abundance NMR: an efficient tandem to unravel 3D structures of unlabeled disulfide rich peptides

Herve Meudal , Françoise Paquet , Laurence Jouvensal , V. Aucagne , A.F. Delmas et al.

21e congrès du Groupe Français des Peptides et des Protéines (GFPP21), May 2019, Amboise, France

Poster de conférence hal-02919180v1

Synthesis of aryl-thioglycopeptides through chemoselective Pd-catalyzed conjugation

T.M. Vishwanatha , D. Montoir , Mehdi Amoura , Z. El Ababsa , E. Yen-Pon et al.

21. Réunion du Groupe Français des Peptides et des Protéines (GFPP21), May 2019, Amboise, France

Poster de conférence hal-02893488v1

An improved synthesis of N-Hnb-Cys peptide crypto-thioesters - studies on the epimerization of cysteine during solid-phase reductive amination

S. Abboud , Mehdi Amoura , V.P. Terrier , A.F. Delmas , V. Aucagne

8th Chemical Protein Synthesis meeting (CPS2019), Jun 2019, Berlin, Germany

Poster de conférence hal-02893426v1

Second generation N-2-hydroxybenzyl-cysteine peptide crypto-thioesters for native chemical ligation

Mehdi Amoura , V.P. Terrier , A.F. Delmas , V. Aucagne

35th European Peptide Symposium (EPS35), Aug 2018, Dublin, Ireland

Poster de conférence hal-02894157v1

Long-lasting increase of gonadotropins by rational design of lipophilic kisspeptin analogs

T.M. Vishwanatha , C. Decourt C , V. Robert , M. Galibert , J.-B. Madinier et al.

2018 International Symposium on Chemical Biology, Jan 2018, Genève, Switzerland

Poster de conférence hal-02894282v1

Design and optimization of alternative thioester precursors to simplify protein synthesis by native chemical ligation

Mehdi Amoura , V.P. Terrier , A.F. Delmas , V. Aucagne

25th SCT Young Research Fellows meeting, Mar 2018, Orléans, France

Poster de conférence hal-02894273v1

A single injection of compound 6 evoked an LH surge and ovulation in 18 week old gilts

R. Cameron , R. Kirkwood , M. Beltramo , V. Aucagne , A. Tilbrook

100th annual meeting of the Endocrine Society (ENDO 2018), Mar 2018, Chicago, Illinois, United States. Endocrine Reviews, 39 (Suppl. 1), pp.281-282, The Endocrine Society’s 100th Annual Meeting and Expo. ⟨10.1093/edrv/39.supp.1⟩

Poster de conférence hal-02894272v1

The kisspeptin analog C6 triggers ovulation in non-breeding ewe in the absence of progestogen priming

C. Decourt , V. Robert , Didier Lomet , V. Aucagne , Massimiliano Beltramo

9. International Congress of Neuroendocrinology (ICN 2018), Jul 2018, Toronto, Canada

Poster de conférence hal-02894264v1

Rational design of kisspeptin analogs for the control of the reproductive system

T.M. Vishwanatha , C. Decourt , V.P. Terrier , V. Robert , J.-B. Madinier et al.

25th SCT Young Research Fellows meeting, Mar 2018, Orléans, France

Poster de conférence hal-02894277v1

Development of chemo-enzymatic methodologies for the total synthesis of proteins through solid-supported chemical ligation

S. Abboud , V. Piller , S. Papot , A.F. Delmas , V. Aucagne

31e Colloque Biotechnocentre, Oct 2018, Seillac, France

Poster de conférence hal-02894152v1

Near-infrared emitting lanthanide molecules, macromolecules and nanomaterials: New perspectives of optical biological imaging of living systems

S.V. Eliseeva , V. Aucagne , A.F. Delmas , S. Petoud , I. Gillaizeau

GDR AIm 2018 - 1ères Journées du GDR AİM: "Agents d'imagerie moléculaire", Jun 2018, Orléans, France

Poster de conférence hal-03326661v1

Synthèse chimique et RMN en abondance naturelle : un tandem efficace pour résoudre les structures 3D de peptides/protéines riches en ponts disulfure

Françoise Paquet , H. Meudal , Laurence Jouvensal , K. Loth , V. Aucagne et al.

5es journées annuelles du GDR MuFoPAM, Oct 2018, Paris, France

Poster de conférence hal-02920025v1

Synthesis of aryl-Thioglycopeptides through chemoselective Pd-catalyzed conjugation

David Montoir , Mehdi Amoura , Zine El Abidine Ababsa , Thimmalapura Marulappa Vishwanatha , Expédite Yen-Pon et al.

35 th European Peptide Symposium, Aug 2018, Dublin, Ireland. 2018

Poster de conférence hal-02734043v1

Incorporation of trifluoromethylated pseudoproline in an entomotoxic knottin: effects on oxidative folding, 3D structure and biological activity

F. Coste , G. Chaume , J.-B. Madinier , I. Rahioui , B. Castaing et al.

35th European Peptide Symposium (EPS35), Aug 2018, Dublin, Ireland

Poster de conférence hal-02894161v1

N-2-Hydroxybenzyl-Cysteine Peptides as Efficient Thioester Surrogates for Native Chemical Ligation

Mehdi Amoura , V.P. Terrier , A.F. Delmas , V. Aucagne

4th Belgian Peptide Group Meeting, Feb 2018, Bruxelles, Belgium

Poster de conférence hal-02894279v1

Chemical synthesis and natural abundance NMR: An efficient tandem to unravel 3D structures of Disulfide Rich Miniproteins

H. Meudal , Laurence Jouvensal , K. Loth , Françoise Paquet , V. Aucagne et al.

35th European Peptide Symposium, Aug 2018, Dublin, Ireland

Poster de conférence hal-02920483v1
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In non-breeding ewes the kisspeptin analog c6 triggers ovulation without progestogen priming

Massimiliano Beltramo , Caroline Decourt , Vincent Robert , Didier Lomet , Vincent Aucagne

9th International Congress of Neuroendocrinology, Jul 2018, Toronto, Canada. , 2018, The 9th International Congress of Neuroendocrinology. Abstract book

Poster de conférence hal-02735160v1

N-2-Hydroxybenzyl-Cysteine Peptides as Efficient Thioester Surrogates for Native Chemical Ligation

Mehdi Amoura , V.P. Terrier , D. Lelièvre , A.F. Delmas , V. Aucagne

7th Chemical Protein Synthesis meeting (CPS 2017), Sep 2017, Haifa, Israel

Poster de conférence hal-02894290v1

Development of highly base-labile linkers for the catch-and-release purification of difficult peptides. Application to Avian beta-defensin 2

N. J. Stanley , D. Lelièvre , A.F. Delmas , Vincent Aucagne

20e congrès annuel du Groupe Français des Peptides et Protéines (GFPP), Mar 2017, Arcachon, France.

Poster de conférence hal-02453245v1

NCL-based synthesis, 3D structure and first insight into antimicrobial properties of Cg-BigDef1, an oyster big defensin active at high salinity

A. Delmas , K. Loth , Herve Meudal , V. Terrier , R.D. Rosa et al.

NMR: a tool for Biology Xth, Jan 2017, Paris, France

Poster de conférence hal-02453460v1

N-2-Hydroxybenzyl-Cysteine Peptides as Efficient Thioester Surrogates for Native Chemical Ligation

Mehdi Amoura , V.P. Terrier , D. Lelièvre , A.F. Delmas , V. Aucagne

25th American Peptide Symposium (APS 25), Jun 2017, Whistler, Canada

Poster de conférence hal-02894293v1

Pattern of LH secretion after repeated treatment with kisspeptin analog C6 reveals differential sensitivity between mice and ewes

C. Decourt , V. Robert , D. Lomet , Vincent Aucagne , G. Anderson et al.

42. Colloque de la société de neuroendocrinologie (SNE 2017), Sep 2017, Dijon, France

Poster de conférence hal-02894288v1

Investigation of tachyphylaxis of LH response following repeated injections of the kisspeptin analog C6

Caroline Decourt , Vincent Robert , Didier Lomet , Karine Anger , A. Delmas et al.

Colloque International NeuroFrance 2017, May 2017, Bordeaux, France. 2017, Colloque International NeuroFrance 2017

Poster de conférence hal-01605114v1

Design of a New N-Terminal Linker for the Capture-and-Release Purification of Biologically-Relevant Disulfide-Rich Peptides

A. Casas-Mora , M. Galibert , A.F. Delmas , V. Aucagne

25th American Peptide Symposium (APS 25), Jun 2017, Whistler, Canada

Poster de conférence hal-02894295v1

NCL-based total synthesis of spermaurin, a scorpion venom disulfide-rich miniprotein that improves sperm motility and fertilization in mammals

Vincent Aucagne , E. Schmitt , P. Bulet , C. Arnoult.

20e congrès annuel du Groupe Français des Peptides et Protéines (GFPP), Mar 2017, Arcachon, France.

Poster de conférence hal-02453195v1

Do endogenous kisspeptins and synthetic agonist C6 trigger different intracellular responses?

Vincent Robert , Vincent Aucagne , Caroline Decourt , Massimiliano Beltramo

42e colloque de la société de neuroendocrinologie (SNE 2017), Sep 2017, Dijon, France. 2017, 42ème Colloque de la Société de Neuroendocrinologie

Poster de conférence hal-02733747v1

Second generation N-2-hydroxybenzyl-cysteine peptide crypto-thioesters: achieving very fast NCL kinetics at neutral pH

Mehdi Amoura , V. P. Terrier , A.F. Delmas , Vincent Aucagne

20e congrès annuel du Groupe Français des Peptides et Protéines (GFPP), Mar 2017, Arcachon, France

Poster de conférence hal-02453275v1

Investigation of a kisspeptin analog effects both on synchronization of ovulation and puberty onset in domestic mammals and in rodents

Caroline Decourt , Vincent Robert , Didier Lomet , Vincent Aucagne , Greg Anderson et al.

ReproSciences 2017, Apr 2017, Tours, France. 75 p., 2017, 2èmes Journées Scientifiques du GdR Repro

Poster de conférence hal-01603310v1

NCL-based synthesis, 3D structure and first insight into antimicrobial properties of Cg-BigDef1, an oyster big defensin active at high salinity

A.F. Delmas , K. Loth , Herve Meudal , V.P. Terrier , R.D. Rosa et al.

20e congrès annuel du Groupe Français des Peptides et Protéines (GFPP), Mar 2017, Arcachon, France

Poster de conférence hal-02894301v1

Induction of fertile ovulation and puberty advancement by a new kisspeptin analog

Caroline Decourt , Vincent Robert , Didier Lomet , Karine Anger , M. Galibert et al.

18th International Congress on Animal Reproduction (ICAR), Jun 2016, Tours, France. 676 p., 2016, 18th International Congress on Animal Reproduction (ICAR)

Poster de conférence hal-01604087v1

A new selective kisspeptin analog, C6, that advance puberty in mice and stimulate fertile ovulation in ewe

M. Beltramo , V. Robert , D. Lomet , K. Anger , M. Galibert et al.

British Society for Neuroendocrinology Annual Meeting, Sep 2016, Glasgow, United Kingdom

Poster de conférence hal-02453336v1

A capture-and-release purification strategy to simplify the synthesis of disulfide-rich peptides

A. Casas-Mora , M. Galibert , A.F. Delmas , V. Aucagne

1st PSL Chemical Biology Meeting, Dec 2016, Paris, France.

Poster de conférence hal-02453303v1

Native Chemical ligation simplifies the access of multi-domain antimicrobial peptides: application to the study of big-defensins

A.F. Delmas , V.P. Terrier , R.D. Rosa , A. Bressan , P. Marceau et al.

34th European Peptide Symposium 2016 (EPS2016), Sep 2016, Leipzig, Germany

Poster de conférence hal-02895296v1

A straightforward strategy for automated Fmoc-based synthesis of peptide “crypto-thioesters”. Application to the total synthesis of biologically-relevant disulfide-rich peptides

V. P. Terrier , H. Adihou , D. Lelièvre , Mehdi Amoura , A.F. Delmas et al.

Journées de Chimie Organique de la Société Chimique de France (JCO2016), Dec 2016, Palaiseau, France.

Poster de conférence hal-02453318v1

Laligation native simplifie l’étude de l’activité etdu mécanismed’action des peptides antimicrobiens à multiples domaines :cas des Big défensines d’huître.

Agnes Vergnes , Victor P. Terrier , Bressan Albert , Rafael Diego Rosa , Vincent Aucagne et al.

IIIèmes journées annuelles MuFoPAM « MultiFonction des Peptides AntiMicrobiens », Oct 2016, Tours, France

Poster de conférence hal-02128427v1

Induction of synchronized fertile ovulation by a new selective agonist of kisspeptin receptor

Caroline Decourt , Vincent Robert , Didier Lomet , Karine Anger , Mathieu Galibert et al.

1 Journées du GdR 3606 Repro, Apr 2015, Rennes, France. 105 p., 2015, 1ères Journées Scientifiques du GdR Repro

Poster de conférence hal-02742326v1

Rational design of triazolo-lipopeptides analogs of kisspeptin inducing a long-lasting increase of gonadotropins

Vincent Aucagne , Vincent Robert , Mathieu Galibert , Jean-Baptiste Madinier , P. Marceau et al.

24. Meeting of the American Peptide Society, Jun 2015, Orlando, United States. 2015, 24th Meeting of the American Peptide Society

Poster de conférence hal-02741835v1

Rational design of triazolo-lipopeptides analogs of kisspeptin inducing a long-lasting increase of gonadotrophins

Vincent Aucagne , Vincent Robert , Mathieu Galibert , Jean-Baptiste Madinier , P. Marceau et al.

19. Congrès du Groupe Français des Peptides et des Protéines, May 2015, Port-Bail, United States. 2015

Poster de conférence hal-02793091v1

Development of new kisspeptin analogs to stimulate the reproductive system

Caroline Decourt , Karine Anger , Vincent Robert , Vincent Aucagne , Mathieu Galibert et al.

International Conference on Gonadotropins & Receptors, Sep 2014, Tours, France. , 2014, ICGRIII International Conference on Gonadotropins & Receptors

Poster de conférence hal-02744014v1
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Design and functional profiling of new KISS1R agonists

Massimiliano Beltramo , V. Aucagne , Vincent Robert , M. Galibert , J.B. Madinier et al.

2. Annual Meeting of the GDR RCPG-PhysioMed, Oct 2013, Illkirch, France. 2013, 2nd Annual Meeting of the GDR RCPG-PhysioMed

Poster de conférence hal-02745908v1

Improvement of the chemical production of β-defensins including straightforward attribution of disulfide bridges

Mathieu Galibert , Chrystelle Derache , Franck Coste , Hervé Meudal , Anne-Christine Lalmanach et al.

18. Réunion du GFPP, May 2013, Sète, France. 1 p., 2013

Poster de conférence hal-02805308v1
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La kisspeptine : une nouvelle voie pour maitriser l’ovulation chez les petits ruminants ?

Massimiliano Beltramo , V. Aucagne , R. Vincent , M. Galibert , J.B. Madinier et al.

5. Journées d'Animation Scientifique du département Phase (JAS Phase 2013), Oct 2013, Paris, France. 2013

Poster de conférence hal-02805330v1

Antibacterial spectrum of avian defensin 2: peculiarities in relationship with structural features

Chrystelle Derache , Emmanuel Kut , Hervé Meudal , Vincent Aucagne , Agnès Delmas et al.

3. International Symposium on Antimicrobial Peptides: Today knowledge and future applications (AMP 2012), Jun 2012, Lille, France. , pp.D-97, 2012

Poster de conférence hal-02807349v1

Improvement of the chemical production of β-defensins including straighforward attribution of disulfide bridges

M. Galibert , Chrystelle Derache , F. Coste , H. Meudal , Anne-Christine Lalmanach et al.

3. International Symposium on Antimicrobial Peptides: Today knowledge and future applications, Jun 2012, Lille, France. , pp.C-43, 2012, AMP 2012 - Antimicrobial peptide symposium

Poster de conférence hal-02748134v1

Synthesis and oxidative folding of functional miniproteins containing three disulfide bridges

Chrystelle Derache , Hervé Meudal , Vincent Aucagne , Anne-Christine Lalmanach , Céline Landon et al.

21e Colloque Biotechnocentre, 2008, Seillac, France. 1 p, 2008

Poster de conférence hal-02818274v1
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Solid phase chemical ligation

S. Abboud , A.F. Delmas , V. Aucagne

Brik Ashraf, Dawson Philip, Liu Lei. Total Chemical Protein Synthesis, Wiley, 2021, 978-3-527-34660-8

Chapitre d'ouvrage hal-02974365v1

(9H‐Fluoren‐9‐yl)methanethiol

Vincent Aucagne

Encyclopedia of Reagents for Organic Synthesis, John Wiley & Sons, Ltd, 2011, ⟨10.1002/047084289X.rn01287⟩

Chapitre d'ouvrage hal-02071829v1