virgile-gueneauPresentation
Instead of eliminating biofilms, couldn't we take advantage of them?
I am currently conducting research on the concept of positive biofilms as part of a scientific collaboration between Lallemand Animal Nutrition company and the Micalis Institute.
The objective of this partnership is to develop microbial solutions aimed at modulating the microbial ecology of surfaces by applying beneficial bacterial consortia selected in the laboratory according to specific criteria.
These beneficial bacteria develop on surfaces in the form of a positive biofilm, limiting the colonization of undesirable bacteria, such as pathogens or spoilage microorganisms.
In practice, I study the synergistic interactions between different beneficial bacteria and decipher the mechanisms involved in their antagonistic effects against undesirable bacteria in multi-species biofilm models.
The results obtained directly contribute to understanding the modes of action of positive biofilms and to the development of next-generation products.
Skills
Microbiology
Confocal laser scanning microscopy
Biofilm
Positive biofilms
Microbial ecology
Microbial Pathogens
Publications
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Vers l'utilisation rationnelle de biofilms positifs pour aider à maîtriser les microorganismes indésirables dans les bâtiments d'élevageBiotechnologie. Université Paris-Saclay, 2023. Français. ⟨NNT : 2023UPASB057⟩
Theses
tel-04353025v1
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Spatial analysis of multispecies bacterial biofilmsMIM 53: Biofilms, Elsevier, 2023, Methods in Microbiology, ⟨10.1016/bs.mim.2023.03.002⟩
Book sections
hal-04087208v1
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The concept of positive biofilm in the context of livestock building surfacesSymposium "Environment and Host Microbiomes - Functional Interactions", May 2023, Saclay, France
Conference poster
hal-04112956v1
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High Content Screening Confocal Laser Scanning Microscopy (HCS-CLSM) to decipher the mechanisms of bacterial pathogens exclusion by positive biofilmsEMBO Workshop Adherent microbial communities: Quantitative approaches from single cell to ecosystems, Oct 2022, Cargèse, France
Conference poster
hal-03821033v1
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Emergent properties of a multi-species positive biofilm : structural and chemical analysis of the extracellular matrix.PhyChemCell2022, Oct 2022, Saclay, France
Conference poster
hal-03821054v1
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