Xavier Leray

Chargé de Recherche INRAE
25
Documents
Affiliation actuelle
  • Biologie des Oiseaux et Aviculture (BOA)
Identifiants chercheurs
Contact

Présentation

Bonjour ! Je suis chargé de recherche à l’Institut national de recherche pour l’agriculture, l’alimentation et l’environnement (INRAE), en poste depuis 2023 dans l’équipe Biologie de l’œuf et Physiologie de la Poule au laboratoire Biologie des Oiseaux et Avicultures situé à Nouzilly près de Tours.

La ligne conductrice de mes travaux de recherche s’articule autour du transfert de molécules et de la transduction des signaux à travers les membranes biologiques en regard de leurs rôles physiologiques. J'étudie actuellement les processus de biominéralisation chez les oiseaux et plus particulièrement le système de transport de minéraux par voie vésiculaire par des approches d'imagerie et d'analyse expressionnelle.

Publications

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Publications

Image document

Towards the convergent therapeutic potential of G protein‐coupled receptors in autism spectrum disorders

Anil Annamneedi , Caroline Gora , Ana Dudas , Xavier Leray , Véronique Bozon et al.
British Journal of Pharmacology, 2023, 2023, pp.1-24. ⟨10.1111/bph.16216⟩
Article dans une revue (article de synthèse) hal-04220553 v1

Tonic inhibition of the chloride/proton antiporter ClC-7 by PI(3,5)P2 is crucial for lysosomal pH maintenance

Xavier Leray , Jacob Hilton , Kamsi Nwangwu , Alissa Becerril , Vedrana Mikusevic et al.
eLife, 2022, 11, ⟨10.7554/eLife.74136⟩
Article dans une revue hal-04516368 v1
Image document

Arginine-selective modulation of the lysosomal transporter PQLC2 through a gate-tuning mechanism

Xavier Leray , Rossella Conti , Yan Li , Cécile Debacker , Florence Castelli et al.
Proceedings of the National Academy of Sciences of the United States of America, 2021, 118 (32), pp.e2025315118. ⟨10.1073/pnas.2025315118⟩
Article dans une revue hal-03320088 v1
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Neuronal Nicotinic Receptors Are Crucial for Tuning of E/I Balance in Prelimbic Cortex and for Decision-Making Processes

Elsa Pittaras , Alexis Faure , Xavier Leray , Elina Moraitopoulou , Arnaud Cressant et al.
Frontiers in Psychiatry, 2016, 7, pp.171. ⟨10.3389/fpsyt.2016.00171⟩
Article dans une revue hal-01405237 v1

Quinuclidine compounds differently act as agonists of Kenyon cell nicotinic acetylcholine receptors and induced distinct effect on insect ganglionic depolarizations

Monique Mathe-Allainmat , Daniel Swale , Xavier Leray , Yassine Benzidane , Jacques Lebreton et al.
INVERTEBRATE NEUROSCIENCE, 2013, 13 (2), pp.167-177. ⟨10.1007/s10158-013-0160-2⟩
Article dans une revue istex hal-02142391 v1

Pretreatment of the cockroach cercal afferent/giant interneuron synapses with nicotinoids and neonicotinoids differently affects acetylcholine and nicotine-induced ganglionic depolarizations

Benzidane Yassine , Xavier Leray , Charlotte Falaise , Sophie Quinchard , José Pedro Ceron-Carrasco et al.
Invertebrate Neuroscience, 2013, 13 (2), pp.91-97. ⟨10.1007/s10158-013-0151-3⟩
Article dans une revue istex hal-02268785 v1
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L’œuf, un aliment multifacette

Magali Chesse , Clara Dombre , Joël Gautron , Clément Gérard , Nicolas Guyot et al.
Fête de la science 2024 : un océan de savoirs, Centre Sciences, Oct 2024, Tours, France
Communication dans un congrès hal-04736378 v1

Discussion Leader: Biology, Physiology and Pathology of Intracellular Channels/Transporters

Xavier Leray
Gordon Research Seminar on Organellar Channels and Transporters, Xiaoli Zhang and Dhondup Lhamo, Aug 2019, West Dover, VT, United States
Communication dans un congrès hal-04653720 v1
Image document

Watching living cells, the building blocks of life

Xavier Leray
Take Your Child To Work Day 2018, FAES@NIH, Apr 2018, Bethesda, MD, United States
Communication dans un congrès hal-04653634 v1

Watching living cells, the building blocks of life

Xavier Leray
Take Your Child To Work Day 2017, FAES@NIH, Apr 2017, Bethesda, MD, United States
Communication dans un congrès hal-04653632 v1

Functional properties of the lysosomal amino acid transporter PQLC2

Xavier Leray , Christine Anne , Anselm A Zdebik , Bruno Gasnier
Gordon Research Conference on Organellar Channels and Transporters, Haoxing Xu and Enrico Martinoia, Jun 2015, West Dover, VT, United States
Communication dans un congrès hal-04652976 v1
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Investigating the interplay between PIKfyve and ClC-7 in lysosomal acidification and trafficking

Xavier Leray , Anowarul Amin , Mary Weston , Joseph Mindell
Gordon Research Conference on Organellar Channels and Transporters, Aug 2019, West Dover, VT, United States.
Poster de conférence hal-04653194 v1
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Investigating the interplay between PIKfyve/PI(3,5)P2 and ClC-7 in lysosomal acidification and trafficking.

Xavier Leray , Anowarul Amin , Mary Weston , Joseph Mindell
63rd Annual Meeting of the Biophysical Society, Mar 2019, Baltimore, MD, United States. , 116 (3), pp.228a, 2019, ⟨10.1016/j.bpj.2018.11.1256⟩
Poster de conférence hal-04653246 v1
Image document

Investigating the interplay between PIKfyve/PI(3,5)P2 and ClC-7 in lysosomal acidification and trafficking

Xavier Leray , Anowarul Amin , Mary Weston , Joseph Mindell
Gordon Research Conference on Lysosomes and Endocytosis, Jun 2018, Andover, NH, United States.
Poster de conférence hal-04653165 v1
Image document

Unusual properties of the lysosomal amino acid transporter PQLC2

Xavier Leray , Yan Li , Anselm A Zdebik , Bruno Gasnier
60th Annual Meeting of the Biophysical Society, Feb 2016, Los angeles, CA, United States.
Poster de conférence hal-04653004 v1
Image document

Unusual properties of the lysosomal amino acid transporter PQLC2

Xavier Leray , Christine Anne , Yan Li , Anselm A Zdebik , Bruno Gasnier
Fifth International Cystinosis Research Symposium, Mar 2016, Irvine, CA, United States
Poster de conférence hal-04652904 v1
Image document

Functional properties of the lysosomal amino acid transporter PQLC2

Xavier Leray , Yan Li , Anselm A Zdebik , Bruno Gasnier
Gordon Research Conference (GRC) on Organellar Channels and Transporters, Jun 2015, West Dover, VT, United States
Poster de conférence hal-04652959 v1
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Molecular mechanism of the lysosomal transporter PQLC2,a rate-limiting step in cysteamine therapy of cystinosis

Xavier Leray , Christine Anne , Anselm A Zdebik , Bruno Gasnier
Fourth International Cystinosis Research Symposium, Feb 2014, Irvine, CA, United States
Poster de conférence hal-04652928 v1
Image document

Identification and characterization of a new cationic amino acid transporter named PQ-Loop-Containing protein 2 (PQLC2)

Adrien Jezegou , Xavier Leray , Elisa Llinares , Christine Anne , Sylvie Kieffer-Jaquinod et al.
19th European Study Group on Lysosomal Diseases (ESGLD) Workshop, Sep 2013, Seggau castle, Austria
Poster de conférence hal-04652798 v1

Functional Study of Lysosomal Nutrient Transporters

Xavier Leray , Corinne Sagné , Bruno Gasnier
Bruno Gasnier; Michael X. Zhu. Ion and Molecule Transport in Lysosomes, CRC Press, 26 p, 2020, 9781138560390. ⟨10.1201/b22460⟩
Chapitre d'ouvrage hal-04521959 v1