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Soluble TIM-3 as a biomarker of progression and therapeutic response in cancers and other of human diseases
Christian Bailly
,
Xavier Thuru
,
Laurence Goossens
,
Jean-François Goossens
Journal articles
hal-03990928v1
|
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A Potential Off-Target Effect of the Wnt/β-Catenin Inhibitor KYA1797K: PD-L1 Binding and Checkpoint Inhibition
Xavier Thuru
,
Romain Magnez
,
Gérard Vergoten
,
Christian Bailly
Journal articles
inserm-03990317v1
|
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Antioxidant Properties and Aldehyde Reactivity of PD-L1 Targeted Aryl-Pyrazolone Anticancer Agents
Natascha Leleu
,
Romain Regnault
,
Hania Ahouari
,
Raphael Le Biannic
,
Mostafa Kouach
et al.
Journal articles
hal-03714935v1
|
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p65/RelA NF‐κB fragments generated by RIPK3 activity regulate tumorigenicity, cell metabolism, and stemness characteristics
Yasmine Touil
,
Céline Latreche‐carton
,
Hassiba El Bouazzati
,
Anne‐lucie Nugues
,
Nathalie Jouy
et al.
Journal articles
hal-03641788v1
|
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A Phosphosite Mutant Approach on LRRK2 Links Phosphorylation and Dephosphorylation to Protective and Deleterious Markers, Respectively
Antoine Marchand
,
Alessia Sarchione
,
Panagiotis Athanasopoulos
,
Hélène Bauderlique-Le Roy
,
Liesel Goveas
et al.
Journal articles
inserm-03625821v1
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Functional Analyses of Two Novel LRRK2 Pathogenic Variants in Familial Parkinson's Disease.
Ilda Coku
,
Eugénie Mutez
,
Sabiha Eddarkaoui
,
Sébastien Carrier
,
Antoine Marchand
et al.
Journal articles
hal-03703786v1
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Direct interaction of TrkA/CD44v3 is essential for NGF-promoted aggressiveness of breast cancer cells
Sarah Trouvilliez
,
Julien Cicero
,
Romain Lévêque
,
Léo Aubert
,
Cyril Corbet
et al.
Journal articles
hal-03641786v1
|
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Microscale Thermophoresis as a Tool to Study Protein Interactions and Their Implication in Human Diseases
Romain Magnez
,
Christian Bailly
,
Xavier Thuru
Journal articles
hal-03857337v1
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Drug Repurposing to Enhance Antitumor Response to PD-1/PD-L1 Immune Checkpoint Inhibitors
Xavier Thuru
,
Romain Magnez
,
Hassiba El-Bouazzati
,
Gérard Vergoten
,
Bruno Quesnel
et al.
Journal articles
hal-03857329v1
|
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Pyrazolones as inhibitors of immune checkpoint blocking the PD-1/PD-L1 interaction
Raphaël Le Biannic
,
Romain Magnez
,
Frédérique Klupsch
,
Natascha Leleu-Chavain
,
Bryan Thiroux
et al.
Journal articles
hal-03641793v1
|
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Modulation of the Gal-9/TIM-3 Immune Checkpoint with α-Lactose. Does Anomery of Lactose Matter?
Christian Bailly
,
Xavier Thuru
,
Bruno Quesnel
Journal articles
hal-03641796v1
|
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Soluble Programmed Death Ligand-1 (sPD-L1): A Pool of Circulating Proteins Implicated in Health and Diseases
Christian Bailly
,
Xavier Thuru
,
Bruno Quesnel
Journal articles
hal-03278429v1
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The EGF Domains of MUC4 Oncomucin Mediate HER2 Binding Affinity and Promote Pancreatic Cancer Cell Tumorigenesis
Nicolas Stoup
,
Maxime Liberelle
,
Céline Schulz
,
Sumeyye Cavdarli
,
Romain Vasseur
et al.
Journal articles
hal-03641795v1
|
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Properties and reactivity of the folic acid and folate photoproduct 6-formylpterin
Jean-François Goossens
,
Xavier Thuru
,
Christian Bailly
Journal articles
hal-03226670v1
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Tau Stabilizes Chromatin Compaction
Thomas Rico
,
Melissa Gilles
,
Alban Chauderlier
,
Thomas Comptdaer
,
Romain Magnez
et al.
Journal articles
hal-03429442v1
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Discovery of a cryptic site at the interface 2 of TEAD – Towards a new family of YAP/TAZ-TEAD inhibitors
Manon Sturbaut
,
Fabrice Bailly
,
Mathilde Coevoet
,
Pasquale Sileo
,
Martine Pugniere
et al.
Journal articles
hal-03429462v1
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Aggressiveness potential of spontaneous canine mucosal melanoma can dictate distinct cancer stem cell compartment behaviors in regard to their initial size and expansion abilities
Yasmine S. Touil
,
Zacharie Segaoula
,
Xavier Thuru
,
Sylvie Zouitina
,
Dominique Tierny
et al.
Journal articles
hal-02873700v1
|
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Enhanced antitumor potential induced by chloroacetate-loaded benzophenones acting as fused tubulin-pyruvate dehydrogenase kinase 1 (PDHK1) ligands
Alina Ghinet
,
Xavier Thuru
,
Emilie Floquet
,
Joëlle Dubois
,
Amaury Farce
et al.
Journal articles
hal-02873632v1
|
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Measurement of Protein-Protein Interactions through Microscale Thermophoresis (MST)
Magnez Romain
,
Bryan Thiroux
,
Morgane Tardy
,
Bruno Quesnel
,
Xavier Thuru
et al.
Journal articles
hal-03185893v1
|
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Chemical reactivity and uses of 1-phenyl-3-methyl-5-pyrazolone (PMP), also known as edaravone
Christian Bailly
,
Paul-Emile Hecquet
,
Mostafa Kouach
,
Xavier Thuru
,
Jean-Francois Goossens
et al.
Journal articles
hal-02873617v1
|
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Combined cytotoxic chemotherapy and immunotherapy of cancer: modern times
Christian Bailly
,
Xavier Thuru
,
Bruno Quesnel
Journal articles
hal-02873714v1
|
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MUC4-ErbB2 Oncogenic Complex: Binding studies using Microscale Thermophoresis
Maxime Liberelle
,
Romain Magnez
,
Xavier Thuru
,
Yamina Bencheikh
,
Séverine Ravez
et al.
Journal articles
hal-02407901v1
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Exploring isoxazoles and pyrrolidinones decorated with the 4,6‐dimethoxy‐1,3,5‐triazine unit as human farnesyltransferase inhibitors
Emilie Floquet
,
Liliana Lucescu
,
Alina Ghinet
,
Sergiu Shova
,
Romain Magnez
et al.
Journal articles
hal-02873628v1
|
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Toward the Discovery of a Novel Class of YAP–TEAD Interaction Inhibitors by Virtual Screening Approach Targeting YAP–TEAD Protein–Protein Interface
Floriane Gibault
,
Mathilde Coevoet
,
Manon Sturbaut
,
Amaury Farce
,
Nicolas Renault
et al.
Journal articles
hal-02060686v1
|
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Isolation and characterization of two canine melanoma cell lines new models for comparative oncology
Zacharie Segaoula
,
Aline Primot
,
Frederic Lepretre
,
Benoit Hedan
,
Emmanuel Bouchaert
et al.
Journal articles
hal-01972446v1
|
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PD-1/PD-L1 binding studies using microscale thermophoresis
Romain Magnez
,
Bryan Thiroux
,
Solenne Taront
,
Zacharie Segaoula
,
Bruno Quesnel
et al.
Journal articles
hal-02873635v1
|
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Synthesis and Biological Evaluation of N -[2-(4-Hydroxyphenylamino)-pyridin-3-yl]-4-methoxy-benzenesulfonamide (ABT-751) Tricyclic Analogues as Antimitotic and Antivascular Agents with Potent in Vivo Antitumor Activity
Zacharie Segaoula
,
Julien Leclercq
,
Valérie Verones
,
Nathalie Flouquet
,
Marie Lecoeur
et al.
Journal articles
hal-02060584v1
|
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Phase I Clinical Pharmacology Study of F14512, a New Polyamine-Vectorized Anticancer Drug, in Naturally Occurring Canine Lymphoma
D. Tierny
,
F. Serres
,
Z. Segaoula
,
I. Bemelmans
,
E. Bouchaert
et al.
Journal articles
hal-02873640v1
|
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Synthesis and biological evaluation of phenstatin metabolites
Alina Ghinet
,
Benoit Rigo
,
Jean-Pierre Hénichart
,
Delphine Le Broc-Ryckewaert
,
Jean Pommery
et al.
Journal articles
hal-02873643v1
|
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Colonization of Mice by Candida albicans Is Promoted by Chemically Induced Colitis and Augments Inflammatory Responses through Galectin‐3
Samir Jawhara
,
Xavier Thuru
,
Annie Standaert‐vitse
,
Thierry Jouault
,
Serge Mordon
et al.
Journal articles
hal-02873647v1
|
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Peroxisome Proliferator-Activated Receptor Gamma Functions As An Antibacterial Factor
L. Peyrin-Biroulet
,
Xavier Thuru
,
C. Vignal
,
L. Dubuquoy
,
E. Merour
et al.
Journal articles
hal-02873659v1
|
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micro-Opioid receptor activation prevents acute hepatic inflammation and cell death.
Dania Chakass
,
David Philippe
,
Edmone Erdual
,
Sébastien Dharancy
,
Mathilde Malapel
et al.
Journal articles
hal-00189969v1
|
|
C-reactive protein (CRP), a novel adipocytokine overexpressed in mesenteric fat in Crohnʼs disease
F. Gonzalez
,
L. Peyrin-Biroulet
,
C. Rousseaux
,
L. Dubuquoy
,
Xavier Thuru
et al.
Journal articles
hal-02873652v1
|
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P176 C-Reactive Protein (crp), a novel adipocytokine overexpressed in Mesenteric fat in Crohn's disease
F. Gonzalez
,
L. Peyrin-Biroulet
,
C. Rousseaux
,
Xavier Thuru
,
C. Decourcelle
et al.
Journal articles
hal-02873662v1
|
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Lactobacillus acidophilus modulates intestinal pain and induces opioid and cannabinoid receptors
Christel Rousseaux
,
Xavier Thuru
,
Agathe Gelot
,
Nicolas Barnich
,
Christel Neut
et al.
Journal articles
hal-02667010v1
|
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C-reactive protein (CRP), a novel adipocytokine overexpressed in mesenteric fat in Crohnʼs disease
F Gonzalez
,
L Peyrin-Biroulet
,
C Rousseaux
,
Laurent Dubuquoy
,
Xavier Thuru
et al.
Journal articles
hal-03113336v1
|
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PPAR as a new therapeutic target in inflammatory bowel diseases
Xavier Thuru
,
L. Dubuquoy
Journal articles
hal-02873664v1
|
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Mu opioid receptor expression is increased in inflammatory bowel diseases: implications for homeostatic intestinal inflammation
Xavier Thuru
,
D Philippe
Journal articles
hal-02873665v1
|
|
Cannabis : des nouvelles fonctions anti-diarrhéiques et anti-cancéreuses
Pierre Desreumaux
,
Xavier Thuru
,
David Philippe
Journal articles
hal-02873668v1
|