Yannick Hommet

29
Documents

Publications

Publications

The Janus face of endogenous neuronal tPA: promoting self-protection and worsening the death of neighboring neurons

Paul Prunotto , Pauline Marie , Laurent Lebouvier , Yannick Hommet , Denis Vivien et al.

Cell Death and Disease, 2024, 15 (4), pp.261. ⟨10.1038/s41419-024-06655-0⟩

Article dans une revue hal-05509814v1

Blood tissue Plasminogen Activator (tPA) of liver origin contributes to neurovascular coupling involving brain endothelial N-Methyl-D-Aspartate (NMDA) receptors

Jonathane Furon , Mervé Yetim , Elsa Pouettre , Sara Martinez de Lizarrondo , Eric Maubert et al.

Fluids and Barriers of the CNS, 2023, 20 (1), pp.11. ⟨10.1186/s12987-023-00411-w⟩

Article dans une revue hal-05509804v1

PKCδ-positive GABAergic neurons in the central amygdala exhibit tissue-type plasminogen activator: role in the control of anxiety

Sara Douceau , Eloïse Lemarchand , Yannick Hommet , Laurent Lebouvier , Charlène Joséphine et al.

Molecular Psychiatry, 2022, 27 (4), pp.2197-2205. ⟨10.1038/s41380-022-01455-4⟩

Article dans une revue hal-05509838v1

Parvalbumin interneuron-derived tissue-type plasminogen activator shapes perineuronal net structure

Matthieu Lépine , Sara Douceau , Gabrielle Devienne , Paul Prunotto , Sophie Lenoir et al.

BMC Biology, 2022, 20 (1), pp.218. ⟨10.1186/s12915-022-01419-8⟩

Article dans une revue hal-05509836v1

Correction to: The choroid plexus: A door between the blood and the brain for tissue-type plasminogen activator

Vincent Zuba , Jonathane Furon , Mathys Bellemain-Sagnard , Sara Martinez de Lazarrondo , Laurent Lebouvier et al.

Fluids and Barriers of the CNS, 2022, 19 (1), pp.83. ⟨10.1186/s12987-022-00383-3⟩

Article dans une revue hal-05509952v1

The choroid plexus: a door between the blood and the brain for tissue-type plasminogen activator

Vincent Zuba , Jonathane Furon , Mathys Bellemain-Sagnard , Sara Martinez de Lizarrondo , Laurent Lebouvier et al.

Fluids and Barriers of the CNS, 2022, 19 (1), pp.80. ⟨10.1186/s12987-022-00378-0⟩

Article dans une revue hal-05509831v1

Factor XII protects neurons from apoptosis by epidermal and hepatocyte growth factor receptor‐dependent mechanisms

Eugénie Garnier , Damien Levard , Carine Ali , Izaskun Buendia , Yannick Hommet et al.

Journal of Thrombosis and Haemostasis, 2021, 19 (9), pp.2235-2247. ⟨10.1111/jth.15414⟩

Article dans une revue hal-05509852v1

Thrombolysis by PLAT/tPA increases serum free IGF1 leading to a decrease of deleterious autophagy following brain ischemia

Audrey Thiebaut , Izaskun Buendia , Vanessa Ginet , Eloise Lemarchand , Mehdi Boutagouga Boudjadja et al.

Autophagy, 2021, 18 (6), pp.1297-1317. ⟨10.1080/15548627.2021.1973339⟩

Article dans une revue hal-05509844v1

Post-synaptic Release of the Neuronal Tissue-Type Plasminogen Activator (tPA)

Sophie Lenoir , Alexandre Varangot , Laurent Lebouvier , Thierry Galli , Yannick Hommet et al.

Frontiers in Cellular Neuroscience, 2019, 13, ⟨10.3389/fncel.2019.00164⟩

Article dans une revue hal-05509856v1

Circulating tPA contributes to neurovascular coupling by a mechanism involving the endothelial NMDA receptors

Antoine Anfray , Antoine Drieu , Vincent Hingot , Yannick Hommet , Mervé Yetim et al.

Journal of Cerebral Blood Flow and Metabolism, 2019, 40 (10), pp.2038-2054. ⟨10.1177/0271678X19883599⟩

Article dans une revue hal-05509854v1

Tissue-Type Plasminogen Activator Controlled Corticogenesis Through a Mechanism Dependent of NMDA Receptors Expressed on Radial Glial Cells

Nolwenn Pasquet , Sara Douceau , Mickael Naveau , Flavie Lesept , Morgane Louessard et al.

Cerebral Cortex, 2019, 29 (6), pp.2482-2498. ⟨10.1093/cercor/bhy119⟩

Article dans une revue hal-05509860v1

PPACK-Desmodus rotundus salivary plasminogen activator (cDSPAα1) prevents the passage of tissuetype plasminogen activator (rt-PA) across the blood-brain barrier and neurotoxicity

Benoit Roussel , Yannick Hommet , Richard Macrez , Torsten Schulz , Karl-Uwe Petersen et al.

Thrombosis and Haemostasis, 2017, 102 (09), pp.606-608. ⟨10.1160/TH09-02-0114⟩

Article dans une revue hal-05509924v1

Tissue-type plasminogen activator exerts EGF-like chemokinetic effects on oligodendrocytes in white matter (re)myelination

Camille Leonetti , Richard Macrez , Mathilde Pruvost , Yannick Hommet , Jérémie Bronsard et al.

Molecular Neurodegeneration, 2017, 12 (1), pp.20. ⟨10.1186/s13024-017-0160-5⟩

Article dans une revue hal-05509865v1

Proportion of single-chain recombinant tissue plasminogen activator and outcome after stroke

Didier Leys , Yannick Hommet , Clémence Jacquet , Solène Moulin , Igor Sibon et al.

Neurology, 2016, 87 (23), pp.2416-2426. ⟨10.1212/WNL.0000000000003399⟩

Article dans une revue hal-05509870v1

Hyperfibrinolysis increases blood–brain barrier permeability by a plasmin- and bradykinin-dependent mechanism

Oscar Marcos-Contreras , Sara Martinez de Lizarrondo , Isabelle Bardou , Cyrille Orset , Mathilde Pruvost et al.

Blood, 2016, 128 (20), pp.2423-2434. ⟨10.1182/blood-2016-03-705384⟩

Article dans une revue hal-05509875v1

Tissue-type plasminogen activator controls neuronal death by raising surface dynamics of extrasynaptic NMDA receptors

Flavie Lesept , Arnaud Chevilley , Julie Jezequel , Laurent Ladépêche , Richard Macrez et al.

Cell Death and Disease, 2016, 7 (11), pp.e2466-e2466. ⟨10.1038/cddis.2016.279⟩

Article dans une revue hal-05509868v1

Conformations of tissue plasminogen activator (tPA) orchestrate neuronal survival by a crosstalk between EGFR and NMDAR

T Bertrand , F Lesept , A Chevilley , S Lenoir , M Aimable et al.

Cell Death and Disease, 2015, 6 (10), pp.e1924-e1924. ⟨10.1038/cddis.2015.296⟩

Article dans une revue hal-05509903v1

tPA promotes ADAMTS-4-induced CSPG degradation, thereby enhancing neuroplasticity following spinal cord injury

Sighild Lemarchant , Mathilde Pruvost , Marie Hébert , Maxime Gauberti , Yannick Hommet et al.

Neurobiology of Disease, 2014, 66, pp.28-42. ⟨10.1016/j.nbd.2014.02.005⟩

Article dans une revue hal-05509908v1

Molecular requirements for safer generation of thrombolytics by bioengineering the tissue-type plasminogen activator A chain

J. Parcq , T. Bertrand , A.F. Baron , Yannick Hommet , E. Anglès-Cano et al.

Journal of Thrombosis and Haemostasis, 2013, 11 (3), pp.539-546. ⟨10.1111/jth.12128⟩

Article dans une revue hal-05509911v1

Unveiling an exceptional zymogen: the single-chain form of tPA is a selective activator of NMDA receptor-dependent signaling and neurotoxicity

J Parcq , T Bertrand , A Montagne , A Baron , R Macrez et al.

Cell Death and Differentiation, 2012, 19 (12), pp.1983-1991. ⟨10.1038/cdd.2012.86⟩

Article dans une revue hal-05509913v1

Tissue‐type plasminogen activator induces plasmin‐dependent proteolysis of intracellular neuronal nitric oxide synthase

Amandine Baron , Yannick Hommet , Frédéric Cassé , Denis Vivien

Biology of the Cell, 2012, 102 (10), pp.539-547. ⟨10.1042/BC20100072⟩

Article dans une revue hal-05509921v1

HMGB-1 promotes fibrinolysis and reduces neurotoxicity mediated by tissue plasminogen activator

Benoit Roussel , Caroline Mysiorek , Ari Rouhiainen , Amandine Jullienne , Jerome Parcq et al.

Journal of Cell Science, 2011, 124 (12), pp.2070-2076. ⟨10.1242/jcs.084392⟩

Article dans une revue hal-05509916v1

Tissue plasminogen activator prevents white matter damage following stroke

Fernando Correa , Maxime Gauberti , Jérôme Parcq , Richard Macrez , Yannick Hommet et al.

Journal of Experimental Medicine, 2011, 208 (6), pp.1229-1242. ⟨10.1084/jem.20101880⟩

Article dans une revue hal-05509917v1

Antibodies Preventing the Interaction of Tissue-Type Plasminogen Activator With N-Methyl- d -Aspartate Receptors Reduce Stroke Damages and Extend the Therapeutic Window of Thrombolysis

Richard Macrez , Pauline Obiang , Maxime Gauberti , Benoit Roussel , Amandine Baron et al.

Stroke, 2011, 42 (8), pp.2315-2322. ⟨10.1161/STROKEAHA.110.606293⟩

Article dans une revue hal-05509915v1

Cerebrovascular protection as a possible mechanism for the protective effects of NXY-059 in preclinical models: An in vitro study

Maxime Culot , Caroline Mysiorek , Mila Renftel , Benoit Roussel , Yannick Hommet et al.

Brain Research, 2009, 1294, pp.144-152. ⟨10.1016/j.brainres.2009.07.035⟩

Article dans une revue istex hal-05509928v1

Age and albumin D site-binding protein control tissue plasminogen activator levels: neurotoxic impact

Benoit Roussel , Richard Macrez , Amandine Jullienne , Véronique Agin , Eric Maubert et al.

Brain - A Journal of Neurology , 2009, 132 (8), pp.2219-2230. ⟨10.1093/brain/awp162⟩

Article dans une revue hal-05509932v1

Toward Safer Thrombolytic Agents in Stroke: Molecular Requirements for NMDA Receptor-Mediated Neurotoxicity

Jose Lopez-Atalaya , Benoit Roussel , Denis Levrat , Jérôme Parcq , Olivier Nicole et al.

Journal of Cerebral Blood Flow and Metabolism, 2008, 28 (6), pp.1212-1221. ⟨10.1038/jcbfm.2008.14⟩

Article dans une revue hal-05509935v1

Sp1 and Smad transcription factors co-operate to mediate TGF-β-dependent activation of amyloid-β precursor protein gene transcription

Fabian Docagne , Cecilia Gabriel , Nathalie Lebeurrier , Sylvain Lesné , Yannick Hommet et al.

Biochemical Journal, 2004, 383 (2), pp.393-399. ⟨10.1042/BJ20040682⟩

Article dans une revue hal-05509939v1

Inhibition of neuronal nitric oxide synthase by 7-methoxyindazole and related substituted indazoles

Pascale Schumann , Valérie Collot , Yannick Hommet , Willy Gsell , François Dauphin et al.

Bioorganic and Medicinal Chemistry Letters, 2001, 11 (9), pp.1153-1156. ⟨10.1016/s0960-894x(01)00156-1⟩

Article dans une revue hal-05509941v1