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Molecular basis for substrate recognition and septum cleavage by AtlA, the major N-acetylglucosaminidase of Enterococcus faecalis
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Comparative mapping of selected structural determinants on the extracellular domains of cholinesterase-like cell-adhesion molecules.
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The neuroligins and the synaptic pathway in Autism Spectrum Disorder.
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The Ig-like domain of Punctin/MADD-4 is the primary determinant for interaction with the ectodomain of neuroligin NLG-1
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Bérangère Pinan-Lucarré
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An evolutionary perspective on the first disulfide bond in members of the cholinesterase-carboxylesterase (COesterase) family: Possible outcomes for cholinesterase expression in prokaryotes
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Overview of the Structure–Function Relationships of Mannose-Specific Lectins from Plants, Algae and Fungi
Annick Barre
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Yves Bourne
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Els J. M. van Damme
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International Journal of Molecular Sciences, 2019, Protein–Carbohydrate Interactions: Structure–Function Relationships, 20 (2), pp.254. ⟨10.3390/ijms20020254⟩
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Substrate binding mode and catalytic mechanism of human heparan sulfate d-glucuronyl C5 epimerase
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Yoan Monneau
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Vincent Delauzun
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Proceedings of the National Academy of Sciences of the United States of America, 2019, 116 (14), pp.6760-6765. ⟨10.1073/pnas.1818333116⟩
Journal articles
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Hot Spots for Protein Partnerships at the Surface of Cholinesterases and Related α/β Hydrolase Fold Proteins or Domains—A Structural Perspective
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Genetic and enzymatic characterization of 3-O-sulfotransferase SNPs associated with Plasmodium falciparum parasitaemia
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Romain R Vivès
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Glycosylate and move! The glycosyltransferase Maf is involved in bacterial flagella formation
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Structural insights into a family 39 glycoside hydrolase from the gut symbiont Bacteroides cellulosilyticus WH2
Ahmad Ali-Ahmad
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Cyclic imine toxins from dinoflagellates: a growing family of potent antagonists of the nicotinic acetylcholine receptors
Jordi Molgó
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Rómulo Aráoz
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NMR assignments of the GacS histidine-kinase periplasmic detection domain from Pseudomonas aeruginosa PAO1
Ahmad Ali-Ahmad
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Olivier Bornet
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Firas Fadel
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Yves Bourne
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Journal articles
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Structure of human lysosomal acid α-glucosidase-a guide for the treatment of Pompe disease
Véronique Roig-Zamboni
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Beatrice Cobucci-Ponzano
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Roberta Iacono
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Maria Carmina Ferrara
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Stanley Germany
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Structure of human lysosomal acid α-glucosidase–a guide for the treatment of Pompe disease
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Beatrice Cobucci-Ponzano
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Roberta Iacono
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Stanley Germany
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Journal articles
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Structural and functional insights into the periplasmic detector domain of the GacS histidine kinase controlling biofilm formation in Pseudomonas aeruginosa
Ahmad Ali-Ahmad
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Firas Fadel
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Corinne Sebban-Kreuzer
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Moly Ba
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Gauthier Dangla Pélissier
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Journal articles
hal-03281300v1
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Relationships of human alpha/beta hydrolase fold proteins and other organophosphate-interacting proteins
Nicolas Lenfant
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P. Marchot
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Arnaud Chatonnet
Journal articles
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Steric and Dynamic Parameters Influencing In Situ Cycloadditions to Form Triazole Inhibitors with Crystalline Acetylcholinesterase
Yves Bourne
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K. Barry Sharpless
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Palmer Taylor
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Journal articles
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Structural basis for carbohydrate binding properties of a plant chitinase-like agglutinin with conserved catalytic machinery
Gerlind Sulzenbacher
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Veronique Roig-Zamboni
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Willy J. Peumans
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Bernard Henrissat
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Journal articles
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Marine Macrocyclic Imines, Pinnatoxins A and G: Structural Determinants and Functional Properties to Distinguish Neuronal α7 from Muscle α12βγδ nAChRs.
Yves Bourne
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Gerlind Sulzenbacher
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Zoran Radić
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Rómulo Aráoz
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Journal articles
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Crystal Structure of Snake Venom Acetylcholinesterase in Complex with Inhibitory Antibody Fragment Fab410 Bound at the Peripheral Site EVIDENCE FOR OPEN AND CLOSED STATES OF A BACK DOOR CHANNEL
Yves Bourne
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Ludovic Renault
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Journal articles
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Structural and biochemical characterization of the -N-acetylglucosaminidase from Thermotoga maritima: Toward rationalization of mechanistic knowledge in the GH73 family
A. Lipski
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V. Lombard
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D. Nurizzo
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D. Mengin-Lecreulx
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Journal articles
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Tracking the origin and divergence of cholinesterases and neuroligins: the evolution of synaptic proteins
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Thierry Hotelier
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Yves Bourne
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P. Marchot
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Arnaud Chatonnet
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Journal articles
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The neuroligins and their neurexin ligands: from structure to function at the synapse
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P. Marchot
Journal articles
hal-03270068v1
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Structural and biochemical characterization of the β-N-acetylglucosaminidase from Thermotoga maritima: toward rationalization of mechanistic knowledge in the GH73 family
Alexandra Lipski
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Mireille Hervé
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Vincent Lombard
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Didier Nurizzo
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Dominique Mengin-Lecreulx
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Journal articles
hal-03219307v1
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Structural and Functional Characterization of the Clostridium perfringens N-Acetylmannosamine-6-phosphate 2-Epimerase Essential for the Sialic Acid Salvage Pathway
Marie-Cécile Pélissier
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Corinne Sebban-Kreuzer
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Françoise Guerlesquin
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James A Brannigan
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Yves Bourne
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Journal articles
hal-03209608v1
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ESTHER, the database of the α/β-hydrolase fold superfamily of proteins: tools to explore diversity of functions
Nicolas Lenfant
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Thierry Hotelier
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Eric Velluet
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Yves Bourne
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P. Marchot
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Journal articles
hal-01218998v1
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Molecular Characterization of Monoclonal Antibodies that Inhibit Acetylcholinesterase by Targeting the Peripheral Site and Backdoor Region
Yves Bourne
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Ludovic Renault
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Sosthène Essono
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Grégoire Mondielli
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Patricia Lamourette
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Journal articles
hal-01771534v1
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Proteins with an alpha/beta hydrolase fold: Relationships between subfamilies in an ever-growing superfamily.
Nicolas Lenfant
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Thierry Hotelier
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Yves Bourne
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P. Marchot
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Arnaud Chatonnet
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Journal articles
hal-01837554v1
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Structural Insights into Antibody Sequestering and Neutralizing of Na+ Channel α-Type Modulator from Old World Scorpion Venom.
Igor P Fabrichny
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Grégoire Mondielli
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Sandrine Conrod
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Marie-France Martin-Eauclaire
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Yves Bourne
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Journal articles
hal-00701162v1
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Structure of a polyisoprenoid binding domain from Saccharophagus degradans implicated in plant cell wall breakdown
Florence Vincent
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David Dal Molin
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Ronald Weiner
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Yves Bourne
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Bernard Henrissat
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Journal articles
hal-03281277v1
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Structural determinants in phycotoxins and AChBP conferring high affinity binding and nicotinic AChR antagonism.
Yves Bourne
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Zoran Radic
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Rómulo Aráoz
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Todd T Talley
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Evelyne Benoit
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Proceedings of the National Academy of Sciences of the United States of America, 2010, 107 (13), pp.6076-81. ⟨10.1073/pnas.0912372107⟩
Journal articles
hal-00464306v1
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A novel α-N-acetylgalactosaminidase family with an NAD+-dependent catalytic mechanism suitable for enzymatic removal of blood group A antigens
Gerlind Sulzenbacher
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Eric P Bennett
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Yves Bourne
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Journal articles
hal-03160498v1
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Crystal Structure of the GalNAc/Gal-Specific Agglutinin from the Phytopathogenic Ascomycete Sclerotinia sclerotiorum Reveals Novel Adaptation of a β-Trefoil Domain
Gerlind Sulzenbacher
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Willy J Peumans
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Pierre Rougé
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Els J M van Damme
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Journal articles
hal-03160488v1
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Conformational remodeling of femtomolar inhibitor-acetylcholinesterase complexes in the crystalline state.
Yves Bourne
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Zoran Radić
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Palmer Taylor
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Journal articles
hal-00625332v1
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Structure-function relationships of the alpha/beta-hydrolase fold domain of neuroligin: A comparison with acetylcholinesterase.
Philippe Leone
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Davide Comoletti
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Palmer Taylor
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Yves Bourne
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P. Marchot
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Journal articles
hal-00482300v1
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Structural insights into the exquisite selectivity of neurexin/neuroligin synaptic interactions.
Philippe Leone
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Géraldine Ferracci
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Sandrine Conrod
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Simon U Garcia
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Journal articles
hal-00625337v1
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Interaction between the sifa virulence factor and its host target skip is essential for salmonella pathogenesis.
Lautaro Diacovich
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Elodie Soprano
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Aude-Agnes Guilhon
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Journal articles
hal-00431846v1
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Distinct oligomeric forms of the Pseudomonas aeruginosa RetS sensor domain modulate accessibility to the ligand binding site
Florence Vincent
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Adam Round
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Aline Reynaud
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Journal articles
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Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal α7 nicotinic acetylcholine receptor
Ryan Hibbs
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Jianxin Shi
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Todd Talley
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Sandrine Conrod
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Journal articles
hal-01809973v1
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Glycosyltransferases, glycoside hydrolases: surprise, surprise!
Bernard Henrissat
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Yves Bourne
Journal articles
hal-03159751v1
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Bacterial glycosidases for the production of universal red blood cells
Qiyong P Liu
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Gerlind Sulzenbacher
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Huaiping Yuan
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Journal articles
hal-03160531v1
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Des glycosidases bactériennes pour du sang universel
Gerlind Sulzenbacher
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Bernard Henrissat
Journal articles
hal-03160530v1
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Gene overexpression and biochemical characterization of the biotechnologically relevant chlorogenic acid hydrolase from Aspergillus niger
Isabelle Benoit
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Yves Bourne
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David Navarro
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Stéphane Canaan
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Journal articles
hal-02658406v1
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Structural Analysis of the Synaptic Protein Neuroligin and Its β-Neurexin Complex: Determinants for Folding and Cell Adhesion
Igor Fabrichny
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Gerlind Sulzenbacher
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Davide Comoletti
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Meghan Miller
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Journal articles
hal-02989328v1
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Substrate and product trafficking through the active center gorge of acetylcholinesterase analyzed by crystallography and equilibrium binding.
Yves Bourne
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Gerlind Sulzenbacher
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Esther Kim
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Palmer Taylor
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Journal articles
hal-00134313v1
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Structural characterization of agonist and antagonist-bound acetylcholine-binding protein from Aplysia californica.
Scott B Hansen
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Tom Huxford
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P. Marchot
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Journal of Molecular Neuroscience, 2006, 30 (1-2), pp.101-2
Journal articles
hal-00134314v1
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LppX is a lipoprotein required for the translocation of phthiocerol dimycocerosates to the surface of Mycobacterium tuberculosis
Gerlind Sulzenbacher
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Stéphane Canaan
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Yann Bordat
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Olivier Neyrolles
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Gustavo Stadthagen
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Journal articles
hal-03160542v1
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Structural comparison of three crystalline complexes of a peptidic toxin with a synaptic acetylcholine recognition protein.
Yves Bourne
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Gerlind Sulzenbacher
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Todd T Talley
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Tom Huxford
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Journal of Molecular Neuroscience, 2006, 30 (1-2), pp.103-4
Journal articles
hal-00134316v1
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Crystal structure of a Cbtx-AChBP complex reveals essential interactions between snake alpha-neurotoxins and nicotinic receptors,
Yves Bourne
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Hansen S. B.
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P. Taylor
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EMBO Journal, 2005, 24, pp.1512-1522
Journal articles
hal-00021395v1
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Crystal structure of the conserved hypothetical protein Rv1155 from Mycobacterium tuberculosis
Stéphane Canaan
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Loréna Scappuccini-Calvo
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Frédéric Frassinetti
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Journal articles
hal-03160568v1
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A. niger protein “EstA”, perhaps a new electrotactin, defines a new class of fungal esterases within the α/β hydrolase fold superfamily
Yves Bourne
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Henri Chahinian
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Ludovic Renault
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Marianick Juin
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Journal articles
hal-03263187v1
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Structural insights into conformational flexibility at the peripheral site and within the active center gorge of AChE, Chem Biol Interact. 157-158, 159-65.
Yves Bourne
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Chemico-Biological Interactions, 2005, 157-158, pp.159-65
Journal articles
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Structural insights into AChE inhibition by monoclonal antibodies
Ludovic Renault
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Sosthène Essono
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Marianick Juin
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Didier Boquet
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Jacques Grassi
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Journal articles
hal-03263196v1
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Structures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and conformations
Scott B Hansen
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Tom Huxford
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P. Marchot
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Palmer Taylor
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Journal articles
hal-03160548v1
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Crystal Structure of E. coli YddE Protein Reveals a Striking Homology With Diaminopimelate Epimerase
Alice Grassick
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Véronique Roig-Zamboni
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Valérie Campanacci
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Christian Cambillau
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Journal articles
hal-03160580v1
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Crystal Structure of Thermotoga maritima ␣-L-Fucosidase INSIGHTS INTO THE CATALYTIC MECHANISM AND THE MOLECULAR BASIS FOR FUCOSIDOSIS
Gerlind Sulzenbacher
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Takeshi Nishimura
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Chris A Tarling
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Stephen G Withers
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Journal articles
hal-03160668v1
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Aspergillus niger Protein EstA Defines a New Class of Fungal Esterases within the α/β Hydrolase Fold Superfamily of Proteins
Yves Bourne
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Alinda A Hasper
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Henri Chahinian
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Marianick Juin
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Leo H de Graaff
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Journal articles
hal-03263177v1
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Freeze-frame inhibitor captures acetylcholinesterase in a unique conformation
Y. Bourne
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Z. Radic
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K. Sharpless
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Proceedings of the National Academy of Sciences of the United States of America, 2004, 101 (6), pp.1449-1454. ⟨10.1073/pnas.0308206100⟩
Journal articles
hal-03263174v1
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Identification of the Catalytic Nucleophile of the Family 29 α-L-Fucosidase from Thermotoga maritima through Trapping of a Covalent Glycosyl-Enzyme Intermediate and Mutagenesis
Chris A Tarling
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Shouming He
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Gerlind Sulzenbacher
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Christophe Bignon
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Yves Bourne
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Journal articles
hal-03160673v1
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Structural insights into ligand interactions at the acetylcholinesterase peripheral anionic site
Yves Bourne
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Palmer Taylor
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Zoran Radic
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P. Marchot
Journal articles
hal-03263169v1
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A medium-throughput crystallization approach
Gerlind Sulzenbacher
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Arnaud Gruez
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Véronique Roig-Zamboni
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Silvia Spinelli
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Christel Valencia
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Journal articles
hal-03160696v1
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Mechanism of Acetylcholinesterase Inhibition by Fasciculin: A 5-ns Molecular Dynamics Simulation
Kaihsu Tai
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Tongye Shen
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Richard Henchman
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Yves Bourne
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P. Marchot
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Journal articles
hal-03263152v1
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Crystal Structure of Streptococcus pneumoniae N -Acetylglucosamine-1-phosphate Uridyltransferase Bound to Acetyl-coenzyme A Reveals a Novel Active Site Architecture
Gerlind Sulzenbacher
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Caroline Peneff
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Florence Fassy
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Yves Bourne
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Journal articles
hal-02007250v1
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Immunocytochemical Localization and Crystal Structure of Human Frequenin (Neuronal Calcium Sensor 1)
Yves Bourne
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Jens Dannenberg
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Verena Pollmann
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P. Marchot
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Olaf Pongs
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Journal articles
hal-03263149v1
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Crystal Structure of Mouse Acetylcholinesterase
Yves Bourne
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Palmer Taylor
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Pierre E Bougis
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P. Marchot
Journal articles
hal-03262510v1
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Conformational Flexibility of the Acetylcholinesterase Tetramer Suggested by X-ray Crystallography*
Yves Bourne
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Jacques Grassi
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Pierre E Bougis
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P. Marchot
Journal of Biological Chemistry, 1999, 274 (43), pp.30370-30376
Journal articles
hal-03262571v1
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Inhibition of mouse acetylcholinesterase by fasciculin: Crystal structure of the complex and mutagenesis of fasciculin
P. Marchot
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Yves Bourne
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Claudine Prowse
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Pierre Bougis
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Palmer Taylor
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Journal articles
hal-03262468v1
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Barley alpha-amylase bound to its endogenous protein inhibitor BASI: crystal structure of the complex at 1.9 A resolution.
F. Vallee
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Yves Bourne
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M. Juy
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Kw Rodenburg
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Structure, 1998, 6, pp.649-659
Journal articles
hal-00313562v1
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Soluble monomeric acetylcholinesterase from mouse: Expression, purification, and crystallization in complex with fasciculin
P. Marchot
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Raimond B.G. Ravelli
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Mia Raves
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Yves Bourne
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Daniel Vellom
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Journal articles
hal-03262129v1
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Acetylcholinesterase Inhibition by Fasciculin: Crystal Structure of the Complex
Yves Bourne
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Palmer Taylor
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P. Marchot
Journal articles
hal-03262026v1
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Structures of a legume lectin complexed with the human lactotransferrin N2 fragment, and with an isolated biantennary glycopeptide: role of the fucose moiety.
Yves Bourne
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Delphine Legrand
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J. Montreuil
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Structure / Struct Fold Des; Structure (Camb ), 1994, 2 (3), pp.209-19
Journal articles
hal-00484451v1
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Primary and three-dimensional structure of lactotransferrin (lactoferrin) glycans.
G. Spik
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Advances in Experimental Medicine and Biology, 1994, 357, pp.21-32
Journal articles
hal-00484469v1
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Characterization, crystallization and preliminary X-ray crystallographic analysis of the complex between barley alpha-amylase and the bifunctional alpha-amylase/subtilisin inhibitor from barley seeds.
F. Vallee
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A. Kadziola
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Yves Bourne
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J. Abe
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B. Svensson
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Journal of Molecular Biology, 1994, 236, pp.368-371
Journal articles
hal-00312986v1
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Crystallization and preliminary X-ray diffraction study of Lathyrus ochrus isolectin II complexed to the human lactotransferrin N2 fragment.
Yves Bourne
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M. P. Nésa
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Pierre Rougé
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J. Mazurier
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Delphine Legrand
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Journal of Molecular Biology, 1992, 227 (3), pp.938-41
Journal articles
hal-00484460v1
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Data bank of three-dimensional structures of disaccharides : Part 2, N-acetyllactosaminic type N-glycans. Comparison with the crystal structure of a biantennary octasaccharide
A. Imberty
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M.M. Delage
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Yves Bourne
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C. Cambillau
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Sarah Perez
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Glycoconjugate Journal, 1991, 8, pp.456-483
Journal articles
hal-02713297v1
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