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Positive regulation of Vav1 by Themis controls CD4 T cell pathogenicity in a mouse model of central nervous system inflammation
Remi Marrocco
,
Isabelle Bernard
,
Emeline Joulia
,
Rebecca Barascud
,
Anne S Dejean
Journal articles
inserm-04757623v1
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THEMIS promotes T cell development and maintenance by rising the signaling threshold of the inhibitory receptor BTLA
Suzanne Mélique
,
Aurélie Vadel
,
Nelly Rouquié
,
Cui Yang
,
Cyrielle Bories
Proceedings of the National Academy of Sciences of the United States of America, 2024, 121 (20), pp.654-663. ⟨10.1073/pnas.2318773121⟩
Journal articles
hal-04757063v1
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Impact of the Multiple Sclerosis-Associated Genetic Variant CD226 Gly307Ser on Human CD8 T-Cell Functions
Elena Morandi
,
Véronique Adoue
,
Isabelle Bernard
,
Ekaterina Friebel
,
Nicolas Nunez
Journal articles
hal-04780777v1
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Eomes-dependent mitochondrial regulation promotes survival of pathogenic CD4+ T cells during inflammation
Emeline Joulia
,
Michaël F. Michieletto
,
Arantxa Agesta
,
Cindy Peillex
,
V Girault
Journal of Experimental Medicine, 2024, Journal of Experimental Medicine, 221 (2), pp.e20230449. ⟨10.1084/jem.20230449⟩
Journal articles
hal-04443514v1
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Increased levels of circulating soluble CD226 in multiple sclerosis
Saniya Kari
,
Florence Bucciarelli
,
Thibault Angles
,
Anne-Cecile Oster
,
Pauline Cauboue
Journal articles
hal-04759633v1
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Cerebrospinal fluid proteomics in recent-onset Narcolepsy type 1 reveals activation of the complement system
Ikram Ayoub
,
Yves Dauvilliers
,
Lucie Barateau
,
Thaïs Vermeulen
,
Emmanuelle Mouton-Barbosa
Journal articles
hal-04291297v1
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THEMIS enhances the magnitude of normal and neuroinflammatory type 1 immune responses by promoting TCR-independent signals
Cui Yang
,
Gaëtan Blaize
,
Rémi Marrocco
,
Nelly Rouquié
,
Cyrielle Bories
Journal articles
hal-04002199v1
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A selective LIS1 requirement for mitotic spindle assembly discriminates distinct T-cell division mechanisms within the T-cell lineage
Jérémy Argenty
,
Nelly Rouquié
,
Cyrielle Bories
,
Suzanne Mélique
,
Valérie Duplan-Eche
Journal articles
hal-04291340v1
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Influenza vaccination induces autoimmunity against orexinergic neurons in a mouse model for narcolepsy
Raphaël Bernard-Valnet
,
David Frieser
,
Xuan-Hung Nguyen
,
Leila Khajavi
,
Clémence Quériault
Journal articles
hal-03669984v1
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Identification of bacterial lipopeptides as key players in IBS
Camille Petitfils
,
Sarah Maurel
,
Gaelle Payros
,
Amandine Hueber
,
Bahija Agaiz
Journal articles
hal-03833107v1
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Peripheral Opioid Receptor Blockade Enhances Epithelial Damage in Piroxicam-Accelerated Colitis in IL-10-Deficient Mice
Xavier Mas-Orea
,
Morgane Sebert
,
Mehdi Benamar
,
Camille Petitfils
,
Catherine Blanpied
Journal articles
hal-03330200v1
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Endogenous control of inflammatory visceral pain by T cell‐derived opioids in IL‐10‐deficient mice
Lilian Basso
,
Mehdi Benamar
,
Xavier Mas‐orea
,
Céline Deraison
,
Catherine Blanpied
Journal articles
hal-03026676v1
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CD5 signalosome coordinates antagonist TCR signals to control the generation of Treg cells induced by foreign antigens
Gaëtan Blaize
,
Hélène Daniels-Treffandier
,
Meryem Aloulou
,
Nelly Rouquié
,
Cui Yang
Proceedings of the National Academy of Sciences of the United States of America, 2020, 117 (23), pp.12969-12979. ⟨10.1073/pnas.1917182117⟩
Journal articles
hal-03016005v1
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Eomes-Dependent Loss of the Co-activating Receptor CD226 Restrains CD8+ T Cell Anti-tumor Functions and Limits the Efficacy of Cancer Immunotherapy
Marianne Weulersse
,
Assia Asrir
,
Andrea C Pichler
,
Lea Lemaitre
,
Matthias Braun
Journal articles
hal-03030829v1
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Treatment of experimental autoimmune encephalomyelitis with engineered bi-specific Foxp3+ regulatory CD4+ T cells.
Manish Malviya
,
Abdelhadi Saoudi
,
Jan Bauer
,
Simon Fillatreau
,
Roland Liblau
Journal articles
hal-03023558v1
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A Virus Hosted in Malaria-Infected Blood Protects against T Cell-Mediated Inflammatory Diseases by Impairing DC Function in a Type I IFN-Dependent Manner
Ali Hassan
,
Myriam Wlodarczyk
,
Mehdi Benamar
,
Emilie Bassot
,
Anna Salvioni
Journal articles
hal-03015978v1
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Pre-transplant CD45RC expression on blood T cells differentiates patients with cancer and rejection after kidney transplantation
Anne-Sophie Garnier
,
Martin Planchais
,
Jérémie Riou
,
Clément Jacquemin
,
Laurence Ordonez
Journal articles
inserm-02100184v1
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Smooth muscle cells-derived CXCL10 prevents endothelial healing through PI3Kγ-dependent T cells response
Adrien Lupieri
,
Natalia F. Smirnova
,
Romain Solinhac
,
Nicole Malet
,
Mehdi Benamar
Journal articles
hal-02349692v1
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The costimulatory molecule CD226 signals through VAV1 to amplify TCR signals and promote IL-17 production by CD4 + T cells
Guillaume Gaud
,
Romain Roncagalli
,
Karima Chaoui
,
Isabelle Bernard
,
Julien Familiades
Journal articles
inserm-04284289v1
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A Natural Variant of the Signaling Molecule Vav1 Enhances Susceptibility to Myasthenia Gravis and Influences the T Cell Receptor Repertoire
Isabelle Bernard
,
Antoine Sacquin
,
Sahar Kassem
,
Mehdi Benamar
,
Celine Colacios
Journal articles
inserm-02439866v1
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The costimulatory molecule CD226 signals through VAV1 to amplify TCR signals and promote IL-17 production by CD4(+) T cells
Guillaume Gaud
,
Romain Roncagalli
,
Karima Chaoui
,
Isabelle Bernard-Cadenat
,
Julien Familiades
Journal articles
hal-02117993v1
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The probiotic strain Escherichia coli Nissle 1917 prevents papain-induced respiratory barrier injury and severe allergic inflammation in mice
Thomas Secher
,
Isabelle Maillet
,
Claire Mackowiak
,
Jessica Le Bérichel
,
Amandine Philippeau
Journal articles
hal-02126575v1
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Oral Administration of the Probiotic Strain Escherichia coli Nissle 1917 Reduces Susceptibility to Neuroinflammation and Repairs Experimental Autoimmune Encephalomyelitis-Induced Intestinal Barrier Dysfunction
Thomas Secher
,
Sahar Kassem
,
Mehdi Benamar
,
Isabelle Bernard-Cadenat
,
Michèle Boury
Journal articles
hal-02624001v1
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Proteomic Analysis of Regulatory T Cells Reveals the Importance of Themis1 in the Control of Their Suppressive Function.
Fanny Duguet
,
Marie Locard-Paulet
,
Marlène Marcellin
,
Karima Chaoui
,
Isabelle Bernard-Cadenat
Journal articles
hal-01595559v1
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Grb2-Mediated Recruitment of USP9X to LAT Enhances Themis Stability following Thymic Selection
Anne Garreau
,
Gaëtan Blaize
,
Jérémy Argenty
,
Nelly Rouquié
,
Audrey Tourdès
Journal articles
inserm-04284309v1
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Vaccine-associated inflammatory diseases of the central nervous system
Xuan-Hung Nguyen
,
Abdelhadi Saoudi
,
Roland Liblau
Journal articles
inserm-04284200v1
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A Natural Variant of the T Cell Receptor-Signaling Molecule Vav1 Reduces Both Effector T Cell Functions and Susceptibility to Neuroinflammation
Sahar Kassem
,
Guillaume Gaud
,
Isabelle Bernard-Cadenat
,
Mehdi Benamar
,
Anne S. Dejean
Journal articles
hal-01438135v1
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Foxo3 transcription factor drives pathogenic T helper 1 differentiation by inducing the expression of eomes
Caroline Stienne
,
Michael Michieletto
,
Mehdi Benamar
,
Nadège Carrié
,
Isabelle Bernard-Cadenat
Journal articles
hal-02631699v1
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Phosphorus-based dendrimer ABP treats neuroinflammation by promoting IL-10-producing CD4+ T Cells
Myriam Hayder
,
Marjorie Varilh
,
Cédric-Olivier Turrin
,
Abdelhadi Saoudi
,
A.-M. Caminade
Journal articles
hal-01923202v1
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An epistatic interaction between Themis1 and Vav1 modulates regulatory T cell function and inflammatory bowel disease development
Christophe Pedros
,
Guillaume Gaud
,
Isabelle Bernard-Cadenat
,
Sahar Kassem
,
Marianne Chabod
Journal articles
hal-02634615v1
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Oral tolerance failure upon neonatal gut colonization with Escherichia coli producing the genotoxin colibactin
Thomas Secher
,
Delphine Payros
,
Camille Brehin
,
Michèle Boury
,
Claude Watrin
Journal articles
hal-02634629v1
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Targeting PI3Kγ activity decreases vascular trauma-induced intimal hyperplasia through modulation of the Th1 response
Natalia F. Smirnova
,
Stephanie Gayral
,
Christophe Pedros
,
Gervaise Loirand
,
Nathalie Vaillant
Journal articles
hal-02519407v1
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VAV 1 and BAFF , via NF κB pathway, are genetic risk factors for myasthenia gravis
Nili Avidan
,
Rozen Le Panse
,
Hanne Harbo
,
Pia Bernasconi
,
Konstantinos Poulas
Annals of Clinical and Translational Neurology, 2014, 1 (5), pp.329-339. ⟨10.1002/acn3.51⟩
Journal articles
inserm-04284319v1
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Rho-GTPases as key regulators of T lymphocyte biology
Abdelhadi Saoudi
,
Sahar Kassem
,
Anne Dejean
,
Guillaume Gaud
Journal articles
inserm-04284152v1
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Genetic control of HgCl2-induced IgE and autoimmunity by a 117-kb interval on rat chromosome 9 through CD4 CD45RChigh T cells
Christophe Pedros
,
O Papapietro
,
C Colacios
,
A Casemayou
,
I Bernard
Journal articles
inserm-04284227v1
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A Higher Risk of Acute Rejection of Human Kidney Allografts Can Be Predicted from the Level of CD45RC Expressed by the Recipients’ CD8 T Cells
Laurence Ordonez
,
Isabelle Bernard-Cadenat
,
Marianne Chabod
,
Jean-François Augusto
,
Valérie Lauwers-Cances
Journal articles
inserm-02164657v1
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A spontaneous mutation of the rat Themis gene leads to impaired function of regulatory T cells linked to inflammatory bowel disease.
Marianne Chabod
,
Christophe Pedros
,
Lucille Lamouroux
,
Céline Colacios
,
Isabelle Bernard-Cadenat
Journal articles
hal-02650348v1
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A Spontaneous Mutation of the Rat Themis Gene Leads to Impaired Function of Regulatory T Cells Linked to Inflammatory Bowel Disease
Marianne Chabod
,
Christophe Pedros
,
Lucille Lamouroux
,
Céline Colacios
,
Isabelle Bernard
Journal articles
inserm-04284166v1
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Cutting Edge: Neuronal Recognition by CD8 T Cells Elicits Central Diabetes Insipidus
Tanja Scheikl
,
Béatrice Pignolet
,
Cécile Dalard
,
Sabine Desbois
,
Danièle Raison
Journal articles
inserm-04284304v1
|
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Tyrosine kinase 2 variant influences T lymphocyte polarization and multiple sclerosis susceptibility
N. Couturier
,
F. Bucciarelli
,
R. Nurtdinov
,
M. Debouverie
,
C. Lebrun-Frenay
Journal articles
inserm-04284261v1
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Effects of BCL-2 over-expression on B cells in transgenic rats and rat hybridomas
Anne-Laure Iscache
,
Séverine Ménoret
,
Laurent Tesson
,
Séverine Rémy
,
Claire Usal
Journal articles
inserm-04284324v1
|
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The p.Arg63Trp polymorphism controls Vav1 functions and Foxp3 regulatory T cell development
Céline Colacios
,
Audrey Casemayou
,
Anne Dejean
,
Frédérique Gaits-Iacovoni
,
Christophe Pedros
Journal articles
inserm-04284249v1
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Tracking antigen-specific CD8+ T cells in the rat using MHC class I multimers.
Valérie Duplan
,
Elsa Suberbielle
,
Catherine E. Napper
,
Etienne Joly
,
Abdelhadi Saoudi
Journal articles
inserm-00212050v1
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The rat Toxo1 locus directs toxoplasmosis outcome and controls parasite proliferation and spreading by macrophage-dependent mechanisms.
Pierre Cavaillès
,
Véronique Sergent
,
Cordelia Bisanz
,
Olivier Papapietro
,
Céline Colacios
Proceedings of the National Academy of Sciences of the United States of America, 2006, 103 (3), pp.744-9. ⟨10.1073/pnas.0506643103⟩
Journal articles
hal-00171244v1
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[The rat Toxo1 locus controls the outcome of the toxoplasmic infection according to a mendelian mode]
Pierre Cavaillès
,
Cordelia Bisanz
,
Olivier Papapietro
,
Céline Colacios
,
Véronique Sergent
Médecine/Sciences, 2006, 22 (8-9), pp.679-80
Journal articles
hal-00171242v1
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Foxp3+ CD25+ regulatory T cells specific for a neo-self-antigen develop at the double-positive thymic stage
Julie Cabarrocas
,
Cécile Cassan
,
Fay Magnusson
,
Eliane Piaggio
,
Lennart T. Mars
Proceedings of the National Academy of Sciences of the United States of America, 2006, 103 (22), pp.8453-8458. ⟨10.1073/pnas.0603086103⟩
Journal articles
hal-03095902v1
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Innate refractoriness of the Lewis rat to toxoplasmosis is a dominant trait that is intrinsic to bone marrow-derived cells.
Véronique Sergent
,
Bastien Cautain
,
Jamal Khalife
,
Didier Deslée
,
Patrick Bastien
Journal articles
hal-00173268v1
|
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Estrogen enhances susceptibility to experimental autoimmune myasthenia gravis by promoting type 1-polarized immune responses.
Laurent Delpy
,
Victorine Douin-Echinard
,
Lucile Garidou
,
Corinne Bruand
,
Abdelhadi Saoudi
Journal of Immunology, 2005, 175 (8), pp.5050-7
Journal articles
hal-00458865v1
|
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Cutting Edge: Vα14-Jα281 NKT Cells Naturally Regulate Experimental Autoimmune Encephalomyelitis in Nonobese Diabetic Mice
Lennart Mars
,
Véronique Laloux
,
Karine Goude
,
Sabine Desbois
,
Abdelhadi Saoudi
Journal articles
hal-03595264v1
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