Alexis Viel

Researcher in veterinary pharmacology at Anses
44
Documents

Domaines de recherche

Médecine vétérinaire et santé animale Bactériologie Pharmacologie

Publications

Publications

Minimum inhibitory concentrations of sulfonamides and trimethoprim for veterinary pathogens: new data for old antibiotics

Nadine Ruchti , Aude Ferran , Andrew Mead , Ludovic Pelligand , Alexis Viel et al.

Veterinary Microbiology, 2026, 312, pp.110784. ⟨10.1016/j.vetmic.2025.110784⟩

Article dans une revue hal-05355767v1
Deposit thumbnail

Population pharmacokinetic modelling of oxytetracycline in rainbow trout (Oncorhynchus mykiss): Effects of route of administration, temperature and ploidy

Alexis Viel , Florine Bachelet , Annaëlle Chailleux , Céline David , Lionel Pineau et al.

Aquaculture, 2026, 610, pp.742917. ⟨10.1016/j.aquaculture.2025.742917⟩

Article dans une revue hal-05141538v1
Deposit thumbnail

Semi-mechanistic PK/PD modelling of enrofloxacin against sensitive Pasteurella multocida : inter-strain variability and prediction of efficacy in pigs

Alexis Viel , Anthony Khaled , Mathias Devreese , Mireille Bruneau , Jérôme Henri

Journal of Applied Microbiology, 2026, ⟨10.1093/jambio/lxag045⟩

Article dans une revue hal-05510220v1
Deposit thumbnail

Population pharmacokinetic modeling of sulfadimethoxine, sulfadiazine and sulfamethoxazole combined to trimethoprim in pigs

Marine Boulanger , Jean-François Taillandier , Jérôme Henri , Mathias Devreese , Siegrid de Baere et al.

Veterinary Quarterly, 2025, 45 (1), pp.2565351. ⟨10.1080/01652176.2025.2565351⟩

Article dans une revue hal-05290011v1
Deposit thumbnail

Presence of antimicrobial residues in edible pig tissues after exposure to cross-contaminated feed: a case study with sulphadimethoxine/trimethoprim

Cristina Santos-Santórum Suárez , Pascal Sanders , Agnès Perrin-Guyomard , Michel Laurentie , Jean-François Taillandier et al.

Food additives & contaminants. Part A. Chemistry, analysis, control, exposure & risk assessment, 2025, pp.1-16. ⟨10.1080/19440049.2025.2467627⟩

Article dans une revue hal-04966079v1
Deposit thumbnail

Pharmacokinetic modeling of sulfamethoxazole-trimethoprim and sulfadiazine-trimethoprim combinations in broilers

Marine Boulanger , Jean-François Taillandier , Jérôme Henri , Mathias Devreese , Siegrid de Baere et al.

Poultry Science, 2024, 103 (11), pp.104200. ⟨10.1016/j.psj.2024.104200⟩

Article dans une revue anses-04687626v1
Deposit thumbnail

PBPK Model To Predict Marbofloxacin Distribution in Edible Tissues and Intestinal Exposure in Pigs

Alexis Viel , Anis Nouichi , Mélanie Le van Suu , Jean-Guy Rolland , Pascal Sanders et al.

Journal of Agricultural and Food Chemistry, 2023, 71 (10), pp.4358-4370. ⟨10.1021/acs.jafc.2c06561⟩

Article dans une revue anses-04167240v1
Deposit thumbnail

Ionophore coccidiostats – disposition kinetics in laying hens and residues transfer to eggs

Abubakar Bello , Jérôme Henri , Alexis Viel , Jonathan Paul Mochel , Błażej Poźniak

Poultry Science, 2023, 102 (1), pp.102280. ⟨10.1016/j.psj.2022.102280⟩

Article dans une revue anses-03922139v1
Deposit thumbnail

Selection of antibiotic resistance in pigs after exposure to feed cross-contaminated with oxytetracycline

Cristina Santos-Santórum Suárez , Pascal Sanders , Murielle Gaugain , Alexis Viel , Frédéric Paboeuf et al.

Veterinary Microbiology, 2023, 287, pp.109924. ⟨10.1016/j.vetmic.2023.109924⟩

Article dans une revue anses-04311332v1
Deposit thumbnail

Estimating the likelihood of ESBL-producing E. coli carriage in slaughter-aged pigs following bacterial introduction onto a farm: A multiscale risk assessment

Catherine Mccarthy , Alexis Viel , Chris Gavin , Pascal Sanders , Robin R.L. Simons

Microbial Risk Analysis, 2022, 20, pp.100185. ⟨10.1016/j.mran.2021.100185⟩

Article dans une revue anses-03441007v1

Presence and Depletion of Sulfadiazine, Trimethoprim, and Oxytetracycline into Feathers of Treated Broiler Chickens and Impact on Antibiotic-Resistant Bacteria

Estelle Dréano , Charlotte Valentin , Jean-François Taillandier , Angélique Travel , Christophe Soumet et al.

Journal of Agricultural and Food Chemistry, 2022, 70 (51), pp.16106-16116. ⟨10.1021/acs.jafc.2c05807⟩

Article dans une revue anses-03918835v1
Deposit thumbnail

A physiologically based pharmacokinetic (PBPK) model exploring the blood-milk barrier in lactating species - A case study with oxytetracycline administered to dairy cows and goats

Jennifer Tardiveau , Lerica Leroux-Pullen , Ronette Gehring , Gaël Touchais , Marie-Pierre Chotard et al.

Food and Chemical Toxicology, 2022, 161, pp.112848. ⟨10.1016/j.fct.2022.112848⟩

Article dans une revue hal-03615752v1

Validation of a LC-MS/MS method for the quantitative analysis of four antibiotics in pig tissues and plasma to assess the risk of transfer of residues to edible matrices after exposure to cross-contaminated feed

Cristina Santos-Santórum Suárez , Pascal Sanders , Agnès Perrin-Guyomard , Dominique Hurtaud-Pessel , Michel Laurentie et al.

Food additives & contaminants. Part A. Chemistry, analysis, control, exposure & risk assessment, 2022, 39 (11), pp.1818-1827. ⟨10.1080/19440049.2022.2126529⟩

Article dans une revue anses-03922498v1
Deposit thumbnail

Tissue distribution, metabolism, and elimination of Victoria Pure Blue BO in rainbow trout: Main metabolite as an appropriate residue marker

Estelle Dubreil-Cheneau , Michel Laurentie , Jean-Michel Delmas , Morgane Danion , Thierry Morin et al.

Chemosphere, 2021, 262, pp.127636. ⟨10.1016/j.chemosphere.2020.127636⟩

Article dans une revue anses-02958944v1
Deposit thumbnail

A liquid chromatography coupled to tandem mass spectrometry method for the quantification of spiramycin and its active metabolite neospiramycin in milk of major and minor species: Validation using the accuracy profile

Jennifer Tardiveau , Gael Touchais , Marie-Pierre Chotard-Soutif , Marie-Pierre Lagrée , Dominique Hurtaud-Pessel et al.

Journal of Chromatography B - Analytical Technologies in the Biomedical and Life Sciences, 2021, 1187, pp.123013. ⟨10.1016/j.jchromb.2021.123013⟩

Article dans une revue anses-03461263v1
Deposit thumbnail

Population pharmacokinetics/pharmacodynamics modelling of enrofloxacin for the three major trout pathogens Aeromonas salmonicida, Flavobacterium psychrophilum and Yersinia ruckeri

Alexis Viel , Antoine Rostang , Marie-Line Morvan , Catherine Fournel , Patrick Daniel et al.

Aquaculture, 2021, 545, pp.737119. ⟨10.1016/j.aquaculture.2021.737119⟩

Article dans une revue anses-03318243v1
Deposit thumbnail

A Population WB-PBPK Model of Colistin and its Prodrug CMS in Pigs: Focus on the Renal Distribution and Excretion

Alexis Viel , Jérôme Henri , Salim Bouchène , Julian Laroche , Jean-Guy Rolland et al.

Pharmaceutical Research, 2018, 35, pp.92. ⟨10.1007/s11095-018-2379-4⟩

Article dans une revue anses-01743743v1
Deposit thumbnail

Lack of experimental evidence to support mcr-1- positive escherichia coli strain selection during oral administration of colistin at recommended and higher dose given by gavage in weaned piglets

Alexis Viel , Jérôme Henri , Agnès Perrin-Guyomard , Julian Laroche , William Couet et al.

International Journal of Antimicrobial Agents, 2017, 51 (1), pp.128-131. ⟨10.1016/j.ijantimicag.2017.04.013⟩

Article dans une revue anses-01570163v1
Deposit thumbnail

MicroRNA-29b Modulates Innate and Antigen-Specific Immune Responses in Mouse Models of Autoimmunity

Apolline Salama , Nolwenn Fichou , Marie Allard , Laurence Dubreil , Laurence de Beaurepaire et al.

PLoS ONE, 2014, 9 (9), pp.e106153. ⟨10.1371/journal.pone.0106153⟩

Article dans une revue hal-02477587v1

Semi-mecanistic PKPD modeling of enrofloxacin against sensitive strains of Pasteurella multocida in pigs

Anthony Khaled , Jérôme Henri , Alexis Viel

Twelfth International Conference on Antimicrobial Agents in Veterinary Medicine (AAVM), Jun 2024, Athènes, Greece

Communication dans un congrès hal-04628898v1

Population PK modeling of OTC in rainbow trout : impact of water temperature and routes of administration

Alexis Viel , Annaëlle Chailleux , Florine Bachelet , Céline David , Lionel Pineau et al.

Twelfth International Conference on Antimicrobial Agents in Veterinary Medicine (AAVM), Jun 2024, Athènes, Greece

Communication dans un congrès hal-04628878v1
Deposit thumbnail

Pharmacocinétique des antibiotiques dans la mamelle : les concentrations efficaces sont-elles atteintes dans les différents compartiments ?

Alexis Viel , Pascal Sanders

Journées Nationales des GTV 2023, Poitiers, May 2023, Poitiers (FR), France

Communication dans un congrès hal-04531021v1
Deposit thumbnail

Réevaluer le schéma posologique des antibiotiques utilisés en pisciculture - exemple de l'enrofloxacine chez la truite

Antoine Rostang , Alexis Viel , Daniel Patrick , Sandrine Baron , Ségolène Calvez

7. Journées de la Recherche Filière Piscicole, ITAVI, Jul 2022, Paris, France. pp.1

Communication dans un congrès hal-04482435v1

Population PKPD modelling of enrofloxacin for the three major trout pathogens A. salmonicida, F. psychrophilum and Y. ruckeri according to fish ploidy

Alexis Viel

Tenth International Conference on Antimicrobial Agents in Veterinary Medicine, Nov 2020, Virtual conference, France

Communication dans un congrès hal-04531066v1

A Population WB-PBPK Model of Colistin and its Prodrug CMS in Pigs and extrapolation to humans

Alexis Viel

Symposium PBPK, Club phase I, Apr 2018, Paris, France. pp.1-38

Communication dans un congrès anses-01985235v1
Deposit thumbnail

Mechanistic Modeling of Antibiotics Transfer across the Blood-Milk Barrier in Ruminants: Case Study of Marbofloxacin

Marc Codaccioni , Jennifer Tardiveau , Jérôme Henri , Nicolas Grégoire , Alexis Viel

59th Congress of the European Societies of Toxicology (EUROTOX 2025) : Toxicology addresses society's real life risks for sustainable health and well being, Sep 2025, Athènes, Greece. Toxicology letters, 411, pp.S195, 2025, ⟨10.1016/j.toxlet.2025.07.468⟩

Poster de conférence hal-05251265v1
Deposit thumbnail

Modélisation pharmacocinétique de population de différents sulfamides associés au triméthoprime chez le porc

Marine Boulanger , Jean-François Taillandier , Marlène Lacroix , Béatrice Roques , Aude A Ferran et al.

57es Journées de la recherche porcine (JRP), Feb 2025, Saint-Malo, France. Ifip, Journées de la recherche porcine en France, 57, 2025, 57es Journées de la recherche porcine

Poster de conférence hal-05206887v1
Deposit thumbnail

Impact of quaternary ammoniums on permeability and intestinal microbiota: a study to detect biomarkers of exposure in rats

Kahina Slimani , Sophie Mompelat , Cécile Vignal , Tahar Ait-Ali , Jean-François Taillandier et al.

16èmes JS du RFMF, Jun 2024, Saint-Malo, France

Poster de conférence hal-05034843v1

Semi-mecanistic PK/PD modeling of three Sulfonamides-Trimethoprim combinations with Echerichia Coli

Marine Boulanger , Sadate Tchalaou , Celia Lechevretel , Alexis Viel , Aude A. Ferran

Twelfth International Conference on Antimicrobial Agents in Veterinary Medicine (AAVM), Jun 2024, Athènes, France.

Poster de conférence hal-04692167v1
Deposit thumbnail

Révision des posologies des combinaisons sulfamides/triméthoprime chez les animaux de production : exemple chez le porc et la volaille (Projet Sultan)

Marine Boulanger , Sadate Tchalaou , Jean-François Taillandier , Béatrice Roques , Aude A. Ferran et al.

Journées Nationales des GTV 2023, May 2023, Poitiers, France

Poster de conférence hal-04711893v1

PBPK modeling to explore dairy cows’ exposure to marbofloxacin and estimate milk withdrawal period

Abderrahmane Meslouh , Alexis Viel , Nicolas Grégoire

GMP 2023 Symposium, Oct 2023, Paris, France.

Poster de conférence hal-04533797v1
Deposit thumbnail

Assessment of the selective effect of colistin on mcr-1-positive Escherichia coli through in vitro co-culture time-kill experiments

Alexis Viel , Charlotte Valentin , Jérôme Henri , Michel Laurentie , Pascal Sanders

Tenth International Conference on Antimicrobial Agents in Veterinary Medicine, Nov 2020, Virtual, France

Poster de conférence anses-03499578v1
Deposit thumbnail

Use of PBPK modeling to explore the pharmacokinetics and renal disposition of CMS/Colistin in piglets as a model for the paediatric population

Alexis Viel , Jérôme Henri , William Couet , Michel Laurentie , Pascal Sanders et al.

CVPT/ESVNU Symposium (European College of Veterinary Pharmacology and Therapeutics & European Society of Veterinary Nephrology and Urology): Pharmacology and the kidney, Jul 2019, London, United Kingdom

Poster de conférence hal-05480054v1

Lack of experimental evidence to support mcr-1-positive Escherichia coli strain selection during oral administration of colistin by gavage in weaned piglets

Alexis Viel , Jérôme Henri , Agnès Perrin-Guyomard , Julian Laroche , William Couet et al.

14th international congress of the European association for veterinary pharmacology and toxicology, Jun 2018, Wroclaw, Poland.

Poster de conférence anses-01985196v1
Deposit thumbnail

The influence of age on colistin methanosulfonate and colistin plasmatic and tissular distribution after intravenous administration of colistin methanosulfonate in pigs background

Alexis Viel , Nicolas Grégoire , Jérôme Henri , Patrice Gobin , Julian Laroche et al.

8th International Conference on Antimicrobial Agents in Veterinary Medicine (AAVM 2016), Aug 2016, Budapest, Hungary

Poster de conférence hal-05480028v1

114. Population pharmacokinetic modelling of different sulphonamides associated with trimethoprim in pigs

Marine Boulanger , J.F. Taillandier , Jérôme Henri , Marlène Z Lacroix , Béatrice Roques et al.

57th Swine Research Days [57es Journées de la Recherche Porcine] (JRP 2025), Feb 2025, Saint-Malo, France. Animal. Science proceedings, 16 (6), pp.896, 2025, ⟨10.1016/j.anscip.2025.08.115⟩

Proceedings/Recueil des communications hal-05406887v1

P19 | Determination of optimal ratios for three sulfonamides/trimethoprim combinations against <i>E. coli</i> using checkerboard and time‐kill assays

Marine Boulanger , Sadate Tchalaou , Béatrice Roques , Aude A. Ferran , Alexis Viel

15th International Congress of the European Association for Veterinary Pharmacology and Toxicology, Journal of Veterinary Pharmacology and Therapeutics, 46 (S1), pp.94-95, 2023, ⟨10.1111/jvp.13298⟩

Proceedings/Recueil des communications hal-04352581v1

O81 | Antibiotic cross‐contamination of feeding stuffs: Assessment of transfer to food of animal origin and risk of antibiotic resistance

Cristina Santos-Santórum Suárez , Murielle Gaugain , Agnes Perrin-Guyomard , Michel Laurentie , Alexis Viel et al.

15th International Congress of the European Association for Veterinary Pharmacology and Toxicology, Journal of Veterinary Pharmacology and Therapeutics, 46 (S1), pp.68-68, 2023, ⟨10.1111/jvp.13247⟩

Proceedings/Recueil des communications hal-04661476v1

Population PK modeling of different sulfonamides in association with trimethoprim in pigs

Alexis Viel , Marine Boulanger , Jean-François Taillandier , Michel Laurentie , Jérôme Henri et al.

15th International Congress of the European Association for Veterinary Pharmacology and Toxicology, Journal of Veterinary Pharmacology and Therapeutics, 46 (S1), pp.82-83, 2023, ⟨10.1111/jvp.13277⟩

Proceedings/Recueil des communications hal-04352560v1