Angélique Stéphanou

52
Documents

Publications

Publications

Image document

A biomechanical model for cell sensing and migration

Arnaud Chauvière , Ian Manifacier , Claude Verdier , Grégory Chagnon , Ibrahim Cheddadi et al.
Computer Methods in Biomechanics and Biomedical Engineering, In press, pp.1-19. ⟨10.1080/10255842.2024.2427112⟩
Article dans une revue hal-04727238 v1
Image document

On the Importance of Acidity in Cancer Cells and Therapy

Alaa Tafech , Angélique Stéphanou
Biology, 2024, 13 (4), pp.225. ⟨10.3390/biology13040225⟩
Article dans une revue (article de synthèse) hal-04527526 v1
Image document

The Role of Mathematical Models in Epidemic Prediction and the Challenges of COVID-19 Comment on 'Data-driven mathematical modeling approaches for COVID-19: A survey' by

E Fanchon , Angélique Stéphanou
Physics of Life Reviews, 2024, 52, pp.55-56. ⟨10.1016/j.plrev.2024.12.002⟩
Article dans une revue hal-04766375 v1
Image document

Modelling the impact of HIF on metabolism and the extracellular matrix: consequences for tumour growth and invasion

Kévin Spinicci , Gibin Powathil , Angélique Stéphanou
Bulletin of Mathematical Biology, In press
Article dans une revue hal-04754067 v1
Image document

Is Cancer Metabolism an Atavism?

Éric Fanchon , Angélique Stéphanou
Cancers, 2024, The Warburg Effect in Cancers, 16 (13), pp.2415. ⟨10.3390/cancers16132415⟩
Article dans une revue hal-04636868 v1
Image document

Generalization of the Ratiometric Method to Extend pH Range Measurements of the BCECF Probe

Alaa Tafech , Céline Beaujean , Yves Usson , Angélique Stéphanou
Biomolecules, 2023, 13 (3), pp.442. ⟨10.3390/biom13030442⟩
Article dans une revue hal-04287591 v1
Image document

A reduced model of cell metabolism to revisit the glycolysis-OXPHOS relationship in the deregulated tumor microenvironment

Pierre Jacquet , Angélique Stéphanou
Journal of Theoretical Biology, 2023, 562, pp.111434. ⟨10.1016/j.jtbi.2023.111434⟩
Article dans une revue hal-03973607 v1
Image document

Characterization of the Intracellular Acidity Regulation of Brain Tumor Cells and Consequences for Therapeutic Optimization of Temozolomide

Alaa Tafech , Pierre Jacquet , Céline Beaujean , Arnold Fertin , Yves Usson et al.
Biology, 2023, 12 (9), pp.1221. ⟨10.3390/biology12091221⟩
Article dans une revue hal-04208184 v1
Image document

Searching for the Metabolic Signature of Cancer: A Review from Warburg’s Time to Now

Pierre Jacquet , Angélique Stéphanou
Biomolecules, 2022, 12 (10), pp.1412. ⟨10.3390/biom12101412⟩
Article dans une revue hal-03813369 v1
Image document

Modelling the role of HIF in the regulation of metabolic key genes LDH and PDH: Emergence of Warburg Phenotype

Kévin Spinicci , Pierre Jacquet , Gibin Powathil , Angélique Stéphanou
Computational and Systems Oncology, 2022, 2 (3), ⟨10.1002/cso2.1040⟩
Article dans une revue hal-03759747 v1
Image document

Can major breakthroughs in cancer be achieved through theoretical models? Comment on “Improving cancer treatments via dynamical biophysical models” by M. Kuznetsov, J. Clairambault and V. Volpert

Angélique Stéphanou
Physics of Life Reviews, 2022, 40, pp.63-64. ⟨10.1016/j.plrev.2021.11.006⟩
Article dans une revue hal-03470089 v1
Image document

Metabolic Reprogramming, Questioning, and Implications for Cancer

Pierre Jacquet , Angélique Stéphanou
Biology, 2021, 10 (2), pp.129. ⟨10.3390/biology10020129⟩
Article dans une revue hal-03151101 v1
Image document

Hybrid Modelling in Oncology: Sucesses, Challenges and Hopes

Angélique Stéphanou , Pascal Ballet , Gibin Powathil
Mathematical Modelling of Natural Phenomena, 2020, 15, ⟨10.1051/mmnp/2019026⟩
Article dans une revue hal-01980757 v1
Image document

HYBRID DATA-BASED MODELLING IN ONCOLOGY: SUCCESSES, CHALLENGES AND HOPES

Angélique Stéphanou , Pascal Ballet , Gibin Powathil
Mathematical Modelling of Natural Phenomena, 2020, 15, ⟨10.1051/mmnp/2019026⟩
Article dans une revue hal-02405782 v1
Image document

A minimal biomechanical model for random cell migration

Ian Manifacier , Arnaud Chauvière , Claude Verdier , G. Chagnon , Ibrahim Cheddadi et al.
Computer Methods in Biomechanics and Biomedical Engineering, 2020, 45th Congress of the Société de Biomécanique, 23 (sup1), pp.S183-S185. ⟨10.1080/10255842.2020.1813420⟩
Article dans une revue hal-03015234 v1
Image document

On the importance of substrate deformations for cell migration

Anais Gagnieu , Grégory Chagnon , Yves Chemisky , Angélique Stephanou , Arnaud Chauvière
Computer Methods in Biomechanics and Biomedical Engineering, 2020, 22 suppl 1, pp.S334-S335. ⟨10.1080/10255842.2020.1714933⟩
Article dans une revue hal-02425956 v1
Image document

A minimal biomechanical model for random cell migration

Ian Manifacier , Arnaud Chauvière , Claude Verdier , Gregory Chagnon , Ibrahim Cheddadi et al.
Computer Methods in Biomechanics & Biomedical Engineering, 2020, ⟨10.1080/10255842.2020.1813420⟩
Article dans une revue hal-02985515 v1
Image document

pH as a potential therapeutic target to improve temozolomide antitumor efficacy : A mechanistic modeling study

Angélique Stéphanou , Annabelle Ballesta
Pharmacology Research & Perspectives, 2019, 7 (1), pp.e00454. ⟨10.1002/prp2.454⟩
Article dans une revue hal-03015254 v1
Image document

Systems Biology, Systems Medicine, Systems Pharmacology: The What and The Why

Angélique Stéphanou , Eric Fanchon , Pasquale Innominato , Annabelle Ballesta
Acta Biotheoretica, 2018, 66 (4), pp.345-365. ⟨10.1007/s10441-018-9330-2⟩
Article dans une revue hal-01975961 v1

How tumour-induced vascular changes alter angiogenesis: Insights from a computational model

Angélique Stéphanou , Anne-Cécile Lesart , J. Deverchere , A. Juhem , A. Popov et al.
Journal of Theoretical Biology, 2017, 419, pp.211-226. ⟨10.1016/j.jtbi.2017.02.018⟩
Article dans une revue hal-01975971 v1
Image document

Towards the Design of a Patient-Specific Virtual Tumour

Flavien Caraguel , Anne-Cécile Lesart , François Estève , Boudewijn Pj van Der Sanden , Angélique Stéphanou
Computational and Mathematical Methods in Medicine, 2016, 2016, pp.7851789. ⟨10.1155/2016/7851789⟩
Article dans une revue hal-01975976 v1

Effects of the hypoxia-mimetic agents DFO and CoCl2 on HeLa-FUCCI cells

Baptiste Bedessem , Marie-Paule Montmasson , Malika Hamel , Françoise Giroud , Angélique Stéphanou
Journal of Cell Biology and Cell Metab, 2015, 2, pp.4-12. ⟨10.24966/cbcm-1943/100004⟩
Article dans une revue hal-01483598 v1

Hybrid Modelling in Cell Biology

Angélique Stéphanou , Vitaly Volpert
Mathematical Modelling of Natural Phenomena, 2015, 10 (1), pp.1-3. ⟨10.1051/mmnp/201510100⟩
Article dans une revue hal-01975989 v1
Image document

A mathematical model of HiF-1α-mediated response to hypoxia on the G1/S transition

Baptiste Bedessem , Angélique Stéphanou
Mathematical Biosciences, 2014, 248, pp.31-9. ⟨10.1016/j.mbs.2013.11.007⟩
Article dans une revue hal-00977635 v1

Mathematical modelling and numerical simulations of actin dynamics in the eukaryotic cell.

Uduak Z George , Angélique Stéphanou , Anotida Madzvamuse
Journal of Mathematical Biology, 2013, 66 (3), pp.547-93. ⟨10.1007/s00285-012-0521-1⟩
Article dans une revue istex hal-00847003 v1

Proceedings of the XXXIInd Seminar of the French-Speaking Society for Theoretical Biology; Saint-Flour (Cantal), France, 10-13 June, 2012.

Nicolas Glade , Angélique Stéphanou
Acta Biotheoretica, 2013, 61 (3), pp.289-90. ⟨10.1007/s10441-013-9201-9⟩
Article dans une revue hal-00977696 v1

A Computational Framework to Assess the Efficacy of Cytotoxic Molecules and Vascular Disrupting Agents against Solid Tumours

Margarita Pons-Salort , Boudewijn van Der Sanden , Aurélie Juhem , Andrei Popov , Angélique Stéphanou
Mathematical Modelling of Natural Phenomena, 2012, 7 (1), pp.49-77. ⟨10.1051/mmnp/20127104⟩
Article dans une revue hal-00847022 v1
Image document

On the importance of the submicrovascular network in a computational model of tumour growth.

Anne-Cécile Lesart , Boudewijn van Der Sanden , Lauriane Hamard , François Estève , Angélique Stéphanou
Microvascular Research, 2012, 84 (2), pp.188-204. ⟨10.1016/j.mvr.2012.06.001⟩
Article dans une revue inserm-00738177 v1

On the Influence of Discrete Adhesive Patterns for Cell Shape and Motility: A Computational Approach

Céline Franco , Tzvetelina Tzvetkova-Chevolleau , Angélique Stéphanou
Mathematical Modelling of Natural Phenomena, 2010, 5 (1), pp.56 - 83. ⟨10.1051/mmnp/20105101⟩
Article dans une revue hal-00847012 v1

Modelling the Impact of Pericyte Migration and Coverage of Vessels on the Efficacy of Vascular Disrupting Agents

Steven Mcdougall , Mark A.J. Chaplain , Angélique Stéphanou , Alexander R.A. Anderson
Mathematical Modelling of Natural Phenomena, 2010, 5 (1), pp.163-202. ⟨10.1051/mmnp/20105108⟩
Article dans une revue hal-00847029 v1
Image document

The motility of normal and cancer cells in response to the combined influence of substrate rigidity and anisotropic microstructure

Tzvetelina Tzvetkova-Chevolleau , Angélique Stéphanou , David Fuard , Jacques Ohayon , Patrick Schiavone et al.
Biomaterials, 2008, 29 (10), pp.1541--1551. ⟨10.1016/j.biomaterials.2007.12.016⟩
Article dans une revue hal-00291559 v1

Spatiotemporal dynamics of actin-rich adhesion microdomains: influence of substrate flexibility

O. Collin , Angélique Stéphanou
Journal of Cell Science, 2006, 119 (9), pp.1914-1925
Article dans une revue hal-01976004 v1

Spatiotemporal dynamics of actin-rich adhesion microdomains: influence of substrate flexibility.

Olivier Collin , Philippe Tracqui , Angélique Stephanou , Yves Usson , Jocelyne Clément-Lacroix et al.
Journal of Cell Science, 2006, 119 (Pt 9), pp.1914-25. ⟨10.1242/jcs.02838⟩
Article dans une revue inserm-00173037 v1

The rigidity in fibrin gels as a contributing factor to the dynamics of in vitro vascular cord formation

Angélique Stephanou , Ghislaine Meskaoui , Vailhé Bruno , Philippe Tracqui
Microvascular Research, 2006, 73 (3), pp.182-190. ⟨10.1016/j.mvr.2006.12.002⟩
Article dans une revue istex hal-00193847 v1

A mathematical model for the dynamics of large membrane deformations of isolated fibroblasts

Angélique Stéphanou
Bulletin of Mathematical Biology, 2004, 66 (5), pp.1119-1154
Article dans une revue hal-01976003 v1

Development of a Preclinical Tool for Measuring Percutaneous Transfer of Dihydrogen, with a View to Optimizing Medical Devices Adapted to Focal Therapies in Dermatology

C. Salomez-Ihl , S. Tanguy , F. Boucher , V. Pascal Mousselard , P. Bedouch et al.
Molecular Hydrogen in Health and Disease, 27, Springer Nature Switzerland, pp.401-416, 2024, Advances in Biochemistry in Health and Disease, ⟨10.1007/978-3-031-47375-3_23⟩
Chapitre d'ouvrage hal-04467191 v1

A computational framework integrating cytoskeletal and adhesion dynamics for modelling cell motility

Angélique Stéphanou
Cell mechanics: from single scale-based models to multiscale modeling, Chapman & Hall/CRC Mathematical and Computational Biology, pp.482, 2010, 9781420094541
Chapitre d'ouvrage hal-00977684 v1

Modélisation de la motilité cellulaire perturbée par l'interaction cellule-substrat

Anais Gagnieu , Arnaud Chauvière , Grégory Chagnon , Yves Chemisky , Angélique Stephanou
38ème Séminaire de la Société Francophone de Biologie Théorique, Jun 2018, Sainf Flour, France
Communication dans un congrès hal-01890322 v1
Image document

Hybrid modelling of mechanical cues in cell migration

Angélique Stéphanou , Simon Lefloch , Arnaud Chauvière
ITM Conference 2015, Workshop on Multiscale and Hybrid Modelling in Cell and Cell Population Biology, Mar 2015, Paris, France. ⟨10.1051/itmconf/20150500012⟩
Communication dans un congrès hal-01550582 v1

Reduced Model For 2D Tumor Growth and Tumor Induced Angiogenesis

Mazen Alamir , Mirko Fiacchini , Angélique Stephanou
ECC 2015 - 14th European Control Conference, Jul 2015, Linz, Austria
Communication dans un congrès hal-01235354 v1

Mathematical Modelling of Fibroblast shape Transition on Arrays of Adhesive Micropatterns with Varying Pitch

Angélique Stéphanou , Tzvetelina Tzvetkova-Chevolleau , David Fuard , Philippe Tracqui , Patrick Schiavone
ECMTB08; European Conference on Mathematical and Theoretical Biology, Jun 2008, Edinburgh, United Kingdom
Communication dans un congrès hal-00340399 v1

Control of cell morphodynamic and displacement orientation by precise tuning between substrate nanopatterning and rigidity

Tzvetelina Tzvetkova-Chevolleau , David Fuard , Patrick Schiavone , Sébastien Decossas , Angélique Stéphanou et al.
Nanobio Europe 2008, Jun 2008, Barcelona, Spain
Communication dans un congrès hal-00340397 v1

The Motility of Normal and Cancer Cells in Response to the Combined Influence of Substrate Rigidity and Anisotropic Nanostructure

Tzvetelina Tzvetkova-Chevolleau , Angélique Stephanou , David Fuard , Jacques Ohayon , Patrick Schiavone et al.
ICBME2008, 13th International Conference on Biomedical Engineering, 2008, Singapore, Singapore
Communication dans un congrès hal-00374519 v1
Image document

The spatio-temporal dynamics of cell membranes deformations and cell migration

Angélique Stéphanou
Modeling and Simulation. Université Joseph-Fourier - Grenoble I, 2002. English. ⟨NNT : ⟩
Thèse tel-00004593 v1