Anne Houdusse

72
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Publications

Publications

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Coupling between the lever arm and active site via an N-terminal extension tunes force sensitivity in the myosin-1 family

Harry W Rathbone , Anne Houdusse
Proceedings of the National Academy of Sciences of the United States of America, 2025, 122 (15), ⟨10.1073/pnas.2502977122⟩
Article dans une revue hal-05028939 v1
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Reassessing the unifying hypothesis for hypercontractility caused by myosin mutations in hypertrophic cardiomyopathy

James Spudich , Neha Nandwani , Julien Robert-Paganin , Anne Houdusse , Kathleen Ruppel
EMBO Journal, 2024, 43 (19), pp.4139-4155. ⟨10.1038/s44318-024-00199-x⟩
Article dans une revue hal-04775427 v1
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Omecamtiv mecarbil and Mavacamten target the same myosin pocket despite opposite effects in heart contraction

Daniel Auguin , Julien Robert-Paganin , Stéphane Réty , Carlos Kikuti , Amandine David et al.
Nature Communications, 2024, 15 (1), pp.4885. ⟨10.1038/s41467-024-47587-9⟩
Article dans une revue hal-04728659 v1
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Aficamten is a small-molecule cardiac myosin inhibitor designed to treat hypertrophic cardiomyopathy

James J Hartman , Darren T Hwee , Julien Robert-Paganin , Chihyuan Chuang , Eva R Chin et al.
Nature Cardiovascular Research, 2024, 3 (8), pp.1003-1016. ⟨10.1038/s44161-024-00505-0⟩
Article dans une revue hal-04775429 v1
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A weak coupling mechanism for the early steps of the recovery stroke of myosin VI: A free energy simulation and string method analysis

Florian E C Blanc , Anne Houdusse , Marco Cecchini
PLoS Computational Biology, 2024, 20 (4), pp.e1012005. ⟨10.1371/journal.pcbi.1012005⟩
Article dans une revue hal-04775430 v1
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How myosin VI traps its off-state, is activated and dimerizes

Louise Canon , Vicente Planelles-Herrero , Young Il Lee , Franck Mayeux , Tianming Lin et al.
Nature Communications, 2023, 14 (1), pp.6732. ⟨10.1038/s41467-023-42376-2⟩
Article dans une revue hal-04293608 v1
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Cryo-EM structure of the folded-back state of human β-cardiac myosin

Alessandro Grinzato , Daniel Auguin , Carlos Kikuti , Neha Nandwani , Dihia Moussaoui et al.
Nature Communications, 2023, 14 (1), pp.3166. ⟨10.1038/s41467-023-38698-w⟩
Article dans une revue hal-04267665 v1
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The many roles of myosins in filopodia, microvilli and stereocilia

Anne Houdusse , Margaret A Titus
Current Biology, 2021, 31 (10), pp.R586-R602. ⟨10.1016/j.cub.2021.04.005⟩
Article dans une revue hal-03281243 v1
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Kinesin-6 Klp9 orchestrates spindle elongation by regulating microtubule sliding and growth

Lara Katharina Krüger , Matthieu Gélin , Liang Ji , Carlos Kikuti , Anne Houdusse et al.
eLife, 2021, 10, pp.e67489. ⟨10.7554/eLife.67489⟩
Article dans une revue hal-03258505 v1
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VASP-mediated actin dynamics activate and recruit a filopodia myosin

Ashley L Arthur , Amy Crawford , Anne Houdusse , Margaret A Titus
eLife, 2021, 10, ⟨10.7554/elife.68082⟩
Article dans une revue hal-03395283 v1
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Integration of Cardiac Actin Mutants Causing Hypertrophic (p.A295S) and Dilated Cardiomyopathy (p.R312H and p.E361G) into Cellular Structures

Constanze Erdmann , Roua Hassoun , Sebastian Schmitt , Carlos Kikuti , Anne Houdusse et al.
Antioxidants , 2021, Oxidative Stress in Cardiovascular Diseases, 10 (7), pp.1082. ⟨10.3390/antiox10071082⟩
Article dans une revue hal-03453111 v1
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Metastasis-suppressor NME1 controls the invasive switch of breast cancer by regulating MT1-MMP surface clearance

Catalina Lodillinsky , Laetitia Fuhrmann , Marie Irondelle , Olena Pylypenko , Xiao-Yan Li et al.
Oncogene, 2021, 40 (23), pp.4019 - 4032. ⟨10.1038/s41388-021-01826-1⟩
Article dans une revue hal-03453132 v1
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The actomyosin interface contains an evolutionary conserved core and an ancillary interface involved in specificity

Julien Robert-Paganin , Xiao-Ping Xu , Mark Swift , Daniel Auguin , James Robblee et al.
Nature Communications, 2021, 12 (1), pp.1892. ⟨10.1038/s41467-021-22093-4⟩
Article dans une revue hal-03453769 v1
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Biological nanomotors, driving forces of life

Anne Houdusse
Comptes Rendus. Biologies, 2021, 343 (4), pp.53-78. ⟨10.5802/crbiol.45>⟩
Article dans une revue hal-03453097 v1

Kinesin-6 Klp9 orchestrates spindle elongation by regulating microtubule sliding and growth

Lara Katharina Krüger , Matthieu Gélin , Liang Ji , Carlos Kikuti , Anne Houdusse et al.
eLife, 2021, 10, ⟨10.7554/eLife.67489⟩
Article dans une revue hal-03453181 v1
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Metastasis-suppressor NME1 controls the invasive switch of breast cancer by regulating MT1-MMP surface clearance

Catalina Lodillinsky , Laetitia Fuhrmann , Marie Irondelle , Olena Pylypenko , Xiao-Yan Li et al.
Article dans une revue hal-03238972 v1
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Force Generation by Myosin Motors: A Structural Perspective

Julien Robert-Paganin , Olena Pylypenko , Carlos Kikuti , H. Lee Sweeney , Anne Houdusse
Chemical Reviews, 2020, 120 (1), pp.5-35. ⟨10.1021/acs.chemrev.9b00264⟩
Article dans une revue hal-03238440 v1
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Single Residue Variation in Skeletal Muscle Myosin Enables Direct and Selective Drug Targeting for Spasticity and Muscle Stiffness

Máté Gyimesi , Ádám Horváth , Demeter Túrós , Sharad Kumar Suthar , Máté Pénzes et al.
Cell, 2020, 183 (2), pp.335-346.e13. ⟨10.1016/j.cell.2020.08.050⟩
Article dans une revue hal-03453772 v1
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Full-length Plasmodium falciparum myosin A and essential light chain PfELC structures provide new anti-malarial targets

Dihia Moussaoui , James P Robblee , Daniel Auguin , Elena B Krementsova , Silvia Haase et al.
eLife, 2020, 9, pp.e60581. ⟨10.7554/elife.60581⟩
Article dans une revue hal-03059341 v1

Optimized filopodia formation requires myosin tail domain cooperation

Ashley Arthur , Livia Songster , Helena Sirkia , Akash Bhattacharya , Carlos Kikuti et al.
Proceedings of the National Academy of Sciences of the United States of America, 2019, 116 (44), pp.22196-22204. ⟨10.1073/pnas.1901527116⟩
Article dans une revue hal-02349330 v1

2nd PSL Chemical Biology Symposium (2019): At the Crossroads of Chemistry and Biology

Marco Lucchino , Anne Billet , Antoine Versini , Harikrishna Bavireddi , Bhanu-Das Dasari et al.
ChemBioChem, 2019, 20 (7), pp.968-973. ⟨10.1002/cbic.201900092⟩
Article dans une revue hal-02324665 v1
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Plasmodium myosin A drives parasite invasion by an atypical force generating mechanism

Julien Robert-Paganin , James Robblee , Daniel Auguin , Thomas Blake , Carol Bookwalter et al.
Nature Communications, 2019, 10 (1), ⟨10.1038/s41467-019-11120-0⟩
Article dans une revue hal-02349247 v1
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Plasmodium myosin A drives parasite invasion by an atypical force generating mechanism

Julien Robert-Paganin , James P Robblee , Daniel Auguin , Thomas C A Blake , Carol S Bookwalter et al.
Nature Communications, 2019, 10, ⟨10.1038/s41467-019-11120-0⟩
Article dans une revue hal-03059356 v1

An intermediate along the recovery stroke of myosin VI revealed by X-ray crystallography and molecular dynamics

Florian Blanc , Tatiana Isabet , Hannah Benisty , H. Lee Sweeney , Marco Cecchini et al.
Proceedings of the National Academy of Sciences of the United States of America, 2018, 115 (24), pp.6213-6218. ⟨10.1073/pnas.1711512115⟩
Article dans une revue hal-02349286 v1
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MYO5B , STX3 , and STXBP2 mutations reveal a common disease mechanism that unifies a subset of congenital diarrheal disorders: A mutation update

Herschel Dhekne , Olena Pylypenko , Arend Overeem , Rosaria Ferreira , K. Joeri van Der Velde et al.
Human Mutation, 2018, 39 (3), pp.333-344. ⟨10.1002/humu.23386⟩
Article dans une revue hal-02349537 v1
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Myosin VI and branched actin filaments mediate membrane constriction and fission of melanosomal tubule carriers

Léa Ripoll , Xavier Heiligenstein , Ilse Hurbain , Lia Domingues , Florent Figon et al.
Journal of Cell Biology, 2018, 217 (8), pp.2709 - 2726. ⟨10.1083/jcb.201709055⟩
Article dans une revue hal-03059386 v1
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Circularly permuted fluorogenic proteins for the design of modular biosensors

Alison G Tebo , Frederico M Pimenta , Martha Zoumpoulaki , Carlos Kikuti , Helena Sirkia et al.
ACS Chemical Biology, 2018, 13 (9), pp.2392 - 2397. ⟨10.1021/acschembio.8b00417⟩
Article dans une revue hal-01909679 v1
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Rab GTPases and their interacting protein partners: Structural insights into Rab functional diversity

Olena Pylypenko , Hussein Hammich , I-Mei Yu , Anne Houdusse
Small GTPases, 2018, 9 (1-2), pp.22-48. ⟨10.1080/21541248.2017.1336191⟩
Article dans une revue hal-02349559 v1
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Hypertrophic cardiomyopathy disease results from disparate impairments of cardiac myosin function and auto-inhibition

Julien Robert-Paganin , Daniel Auguin , Anne Houdusse
Nature Communications, 2018, 9 (1), ⟨10.1038/s41467-018-06191-4⟩
Article dans une revue hal-02349257 v1
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Hypertrophic cardiomyopathy disease results from disparate impairments of cardiac myosin function and auto-inhibition

Julien Robert-Paganin , Daniel Auguin , Anne Houdusse
Nature Communications, 2018, 9, ⟨10.1038/s41467-018-06191-4⟩
Article dans une revue hal-03059371 v1
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The divergent mitotic kinesin MKLP2 exhibits atypical structure and mechanochemistry

Joseph Atherton , I-Mei Yu , Alexander Cook , Joseph M Muretta , Agnel Joseph et al.
Article dans une revue hal-04015847 v1
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Eml1 loss impairs apical progenitor spindle length and soma shape in the developing cerebral cortex

Sara Bizzotto , Ana Uzquiano , Florent Dingli , Dmitry Ershov , Anne Houllier et al.
Scientific Reports, 2017, 7 (1), pp.17308. ⟨10.1038/s41598-017-15253-4⟩
Article dans une revue hal-03825519 v1
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Mechanistic and structural basis for activation of cardiac myosin force production by omecamtiv mecarbil

Vicente J Planelles-Herrero , James J Hartman , Julien Robert-Paganin , Fady I Malik , Anne Houdusse
Nature Communications, 2017, 8 (1), ⟨10.1038/s41467-017-00176-5⟩
Article dans une revue hal-03059358 v1
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Myosin 7 and its adaptors link cadherins to actin

I-Mei Yu , Vicente J Planelles-Herrero , Yannick Sourigues , Dihia Moussaoui , Helena Sirkia et al.
Nature Communications, 2017, 8, pp.15864. ⟨10.1038/ncomms15864⟩
Article dans une revue hal-01984704 v1
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Oxidation of F-actin controls the terminal steps of cytokinesis

Stéphane Frémont , Hussein Hammich , Jian Bai , Hugo Wioland , Kerstin Klinkert et al.
Nature Communications, 2017, 8, pp.1-16. ⟨10.1038/ncomms14528⟩
Article dans une revue hal-01492528 v1
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Coupling fission and exit of RAB6 vesicles at Golgi hotspots through kinesin-myosin interactions

Stephanie Miserey-Lenkei , Hugo Bousquet , Olena Pylypenko , Sabine Bardin , Ariane Dimitrov et al.
Nature Communications, 2017, 8 (1), pp.1254. ⟨10.1038/s41467-017-01266-0⟩
Article dans une revue hal-02349571 v1
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The myosin X motor is optimized for movement on actin bundles

Virginie Ropars , Zhaohui Yang , Tatiana Isabet , Florian Blanc , Kaifeng Zhou et al.
Nature Communications, 2016, 7, pp.12456. ⟨10.1038/ncomms12456⟩
Article dans une revue hal-01361523 v1
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Rab35 GTPase couples cell division with initiation of epithelial apico-basal polarity and lumen opening.

Kerstin Klinkert , Murielle Rocancourt , Anne Houdusse , Arnaud Echard
Nature Communications, 2016, 7, pp.11166. ⟨10.1038/ncomms11166⟩
Article dans une revue pasteur-01301777 v1

Force-producing ADP state of myosin bound to actin

Sarah Wulf , Virginie Ropars , Setsuko Fujita-Becker , Marco Oster , Goetz Hofhaus et al.
Proceedings of the National Academy of Sciences of the United States of America, 2016, 113 (13), pp.E1844-E1852. ⟨10.1073/pnas.1516598113⟩
Article dans une revue hal-02349597 v1
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Coordinated recruitment of Spir actin nucleators and myosin V motors to Rab11 vesicle membranes

Olena Pylypenko , Tobias Welz , Janine Tittel , Martin Kollmar , Florian Chardon et al.
eLife, 2016, 5, pp.e17523. ⟨10.7554/eLife.17523⟩
Article dans une revue hal-02349587 v1
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How Actin Initiates the Motor Activity of Myosin

Paola Llinas , Tatiana Isabet , Lin Song , Virginie Ropars , Bin Zong et al.
Developmental Cell, 2015, 33, pp.401 - 412. ⟨10.1016/j.devcel.2015.03.025⟩
Article dans une revue hal-03059350 v1

How actin initiates the motor activity of Myosin.

Paola Llinas , Tatiana Isabet , Lin Song , Virginie Ropars , Bin Zong et al.
Developmental Cell, 2015, 33 (4), pp.401-12. ⟨10.1016/j.devcel.2015.03.025⟩
Article dans une revue hal-01447817 v1

Myosin VI deafness mutation prevents the initiation of processive runs on actin

Olena Pylypenko , Lin Song , Ai Shima , Zhaohui Yang , Anne Houdusse et al.
Proceedings of the National Academy of Sciences of the United States of America, 2015, 112 (11), pp.E1201-E1209. ⟨10.1073/pnas.1420989112⟩
Article dans une revue hal-02349599 v1
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Myosin VI deafness mutation prevents the initiation of processive runs on actin

Olena Pylypenko , Lin Song , Ai Shima , Zhaohui Yang , Anne Houdusse et al.
Proceedings of the National Academy of Sciences of the United States of America, 2015, 112, pp.E1201 - E1209. ⟨10.1073/pnas.1420989112⟩
Article dans une revue hal-03059375 v1
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Myosin VI Must Dimerize and Deploy Its Unusual Lever Arm in Order to Perform Its Cellular Roles

Monalisa Mukherjea , M Yusuf Ali , Carlos Kikuti , Daniel Safer , Zhaohui Yang et al.
Cell Reports, 2014, 8 (5), ⟨10.1016/j.celrep.2014.07.041⟩
Article dans une revue hal-04775412 v1

Structural basis of myosin V Rab GTPase-dependent cargo recognition

Olena Pylypenko , Wikayatou Attanda , Charles Gauquelin , Marion Lahmani , Doudouh Coulibaly et al.
Proceedings of the National Academy of Sciences of the United States of America, 2013, 110 (51), pp.20443 - 20448. ⟨10.1073/pnas.1314329110⟩
Article dans une revue pasteur-03525520 v1

Processive Steps in the Reverse Direction Require Uncoupling of the Lead Head Lever Arm of Myosin VI

Julie Ménétrey , Tatiana Isabet , Virginie Ropars , Monalisa Mukherjea , Olena Pylypenko et al.
Molecular Cell, 2012, 48 (1), pp.75-86. ⟨10.1016/j.molcel.2012.07.034⟩
Article dans une revue hal-02349630 v1

How myosin motors power cellular functions - an exciting journey from structure to function

Paola Llinas , Olena Pylypenko , Tatiana Isabet , Monalisa Mukherjea , H. Lee Sweeney et al.
FEBS Journal, 2012, 279 (4), pp.551-562. ⟨10.1111/j.1742-4658.2011.08449.x⟩
Article dans une revue hal-02349656 v1
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Processive Steps in the Reverse Direction Require Uncoupling of the Lead Head Lever Arm of Myosin VI

Julie Ménétrey , Tatiana Isabet , Virginie Ropars , Monalisa Mukherjea , Olena Pylypenko et al.
Molecular Cell, 2012, 48 (1), pp.75 - 86. ⟨10.1016/j.molcel.2012.07.034⟩
Article dans une revue hal-03059379 v1
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Role of Insert-1 of Myosin VI in Modulating Nucleotide Affinity

Olena Pylypenko , Lin Song , Gaelle Squires , Xiaoyan Liu , Alan B Zong et al.
Journal of Biological Chemistry, 2011, 286 (13), pp.11716 - 11723. ⟨10.1074/jbc.m110.200626⟩
Article dans une revue hal-03059381 v1

Essential "ankle" in the myosin lever arm

O. Pylypenko , A. Houdusse
Proceedings of the National Academy of Sciences of the United States of America, 2011, 108 (1), pp.5-6. ⟨10.1073/pnas.1017676108⟩
Article dans une revue hal-02349672 v1
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Cadherin-23, myosin VIIa and harmonin, encoded by Usher syndrome type I genes, form a ternary complex and interact with membrane phospholipids

Amel Bahloul , Vincent Michel , Jean-Pierre Hardelin , Sylvie Nouaille , Sylviane Hoos et al.
Human Molecular Genetics, 2010, 19 (18), pp.3557 - 3565. ⟨10.1093/hmg/ddq271⟩
Article dans une revue pasteur-03525648 v1

Structural Basis for Recruitment of Rab6-Interacting Protein 1 to Golgi via a RUN Domain.

Rosario Recacha , Annick Boulet , Florence Jollivet , Solange Monier , Anne Houdusse et al.
Structure / Struct Fold Des; Structure (Camb ), 2009, 17 (1), pp.21-30. ⟨10.1016/j.str.2008.10.014⟩
Article dans une revue inserm-00355625 v1

The structural basis of Arf effector specificity: the crystal structure of ARF6 in a complex with JIP4.

Tatiana Isabet , Guillaume Montagnac , Karine Regazzoni , Bertrand Raynal , Fatima El Khadali et al.
EMBO Journal, 2009, 28 (18), pp.2687 - 2858. ⟨10.1038/emboj.2009.209⟩
Article dans une revue hal-00416785 v1

Electrospray ionization mass spectrometry studies of noncovalent myosin VI complexes reveal a new specific calmodulin binding site

Guillaume Chevreux , Noelle Potier , Alain Dorsselaer , Amel Bahloul , Anne Houdusse et al.
Journal of The American Society for Mass Spectrometry, 2005, 16 (8), pp.1367-1376. ⟨10.1016/j.jasms.2005.03.023⟩
Article dans une revue istex hal-02981194 v1

The unique insert in myosin VI is a structural calcium-calmodulin binding site

A. Bahloul , G. Chevreux , A. Wells , Davy Martin , J. Nolt et al.
Proceedings of the National Academy of Sciences of the United States of America, 2004, 101 (14), pp.4787-4792. ⟨10.1073/pnas.0306892101⟩
Article dans une revue hal-02981195 v1
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Griscelli syndrome restricted to hypopigmentation results from a melanophilin defect (GS3) or a MYO5A F-exon deletion (GS1)

Gaël Ménasché , Chen Hsuan Ho , Ozden Sanal , Jerome Feldmann , Ilhan Tezcan et al.
Journal of Clinical Investigation, 2003, 112 (3), pp.450-456. ⟨10.1172/JCI18264⟩
Article dans une revue inserm-02440362 v1
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Biochemical and functional characterization of Rab27a mutations occurring in Griscelli syndrome patients

Gaël Ménasché , Jérôme Feldmann , Anne Houdusse , Catherine Desaymard , Alain Fischer et al.
Blood, 2003, 101, pp.2736 - 2742. ⟨10.1182/blood-2002-09-2789⟩
Article dans une revue hal-03059374 v1

Biochemical and functional characterization of Rab27a mutations occurring in Griscelli syndrome patients

Gaël Ménasché , Jerome Feldmann , Anne Houdusse , Catherine Desaymard , Alain Fischer et al.
Blood, 2003, 101 (7), pp.2736-2742. ⟨10.1182/blood-2002-09-2789⟩
Article dans une revue inserm-02440369 v1

Myosin VIIa, harmonin and cadherin 23, three Usher I gene products that cooperate to shape the sensory hair cell bundle

Batiste Boëda , Aziz El-Amraoui , Amel Bahloul , Richard Goodyear , Laurent Daviet et al.
EMBO Journal, 2002, 21 (24), pp.6689-6699. ⟨10.1093/emboj/cdf689⟩
Article dans une revue pasteur-05017570 v1

Three-dimensional structure of a heteroclitic antigen-antibody cross-reaction complex.

Véronique Chitarra , Pedro M. Alzari , Graham A. Bentley , T. Narayana Bhat , Jean-Luc Eiselé et al.
Proceedings of the National Academy of Sciences of the United States of America, 1993, 90 (16), pp.7711-7715. ⟨10.1073/pnas.90.16.7711⟩
Article dans une revue pasteur-03136514 v1

Three-dimensional structure and antigen binding specificity of antibodies

D. Tello , S. Spinelli , H. Souchon , F.A. Saul , M.M. Riottot et al.
Biochimie, 1990, 72 (8), pp.507-512. ⟨10.1016/0300-9084(90)90114-v⟩
Article dans une revue istex pasteur-03136462 v1

Myosin Structures.

H Lee Sweeney , Anne Houdusse , Julien Robert-Paganin , H. Lee Sweeney
Myosins - A Superfamily of Molecular Motors, 1239, pp.7-19, 2020, ⟨10.1007/978-3-030-38062-5_2⟩
Chapitre d'ouvrage hal-03053363 v1
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Ca 2+ regulation of Myosin II and Myosin VI during rupture of the Shigella -containing vacuole

Mariette Bonnet , Chun Hui Sun , Jost Enninga , Anne Houdusse , Guy Tran van Nhieu
2024
Pré-publication, Document de travail hal-04775436 v1
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Development of Clinically Viable Non-Muscle Myosin II Small Molecule Inhibitors with Broad Therapeutic Potential

Laszlo Radnai , Erica J Young , Carlos Kikuti , Madalyn Hafenbreidel , Rebecca F Stremel et al.
2024
Pré-publication, Document de travail hal-04775437 v1

Mechanism of small molecule inhibition of Plasmodium falciparum myosin A informs antimalarial drug design

Dihia Moussaoui , James Robblee , Daniel Auguin , Fabio Fisher , Patricia Fagnant et al.
2022
Pré-publication, Document de travail hal-03811821 v1
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Nucleotide-free structures of Kif20A illuminate the atypical allostery in this mitotic kinesin-6

Fanomezana Moutse Ranaivoson , Vincent Crozet , Matthieu P.M.H. Benoît , Amna Abdalla Mohammed Khalid , Carlos Kikuti et al.
2022
Pré-publication, Document de travail hal-03872652 v1
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Hypertrophic cardiomyopathy disease results from disparate impairments of cardiac myosin function and auto-inhibition

Julien Robert-Paganin , Daniel Auguin , Anne Houdusse
2020
Pré-publication, Document de travail hal-03059367 v1
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Structure of Full Length Plasmodium Myosin A and its light chain PfELC, dual targets against malaria parasite pathogenesis

Dihia Moussaoui , James P Robblee , Daniel Auguin , Elena B Krementsova , Silvia Haase et al.
2020
Pré-publication, Document de travail hal-03059369 v1

Structure of Full Length Plasmodium Myosin A and its light chain PfELC, dual targets against malaria parasite pathogenesis

Dihia Moussaoui , James Robblee , Daniel Auguin , Elena Krementsova , Silvia Haase et al.
2020
Pré-publication, Document de travail hal-03053364 v1
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Structure of Full Length Plasmodium Myosin A and its light chain PfELC, dual targets against malaria parasite pathogenesis

Dihia Moussaoui , James P Robblee , Daniel Auguin , Elena B Krementsova , Silvia Haase et al.
2020
Pré-publication, Document de travail hal-03059395 v1

Hypertrophic cardiomyopathy disease results from disparate impairments of cardiac myosin function and auto-inhibition

Julien Robert-Paganin , Daniel Auguin , Anne Houdusse
2020
Pré-publication, Document de travail hal-03053365 v1