Anne Lespine
Publications
Publications
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Selections of macrocyclic lactones resistant Caenorhabditis elegans strains revealed adaptative mechanisms to anthelminticsBridging the Divide Workshop, Astra Bryant (University of Washington) and Elissa Hallem (UCLA), Jun 2025, Davis (Californie), United States |
Deciphering Ivermectin Resistance: Contribution of P-Glycoproteins in Loss-of-Function Strains of Ivermectin-Resistant Caenorhabditis elegansAnti-Helmintics VI, Sep 2024, Toronto, Canada |
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Comparative Transcriptomic Analysis in Macrocyclic Lactone-Resistant C. elegans: the impact of NHR-824th Drug Design & Development Seminar (DDDS) 2024, German Society for Parasitology; Ludwig-Maximilians University Würzburg, Mar 2024, Würzburg, Germany |
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Lipid metabolism and resistance to ivermectin in C. elegansANTI-HELMINTICS VI (2024): DRUGS AND VACCINES FOR CONTROLLING NEMATODE, CESTODE AND TREMATODE PARASITES, Sep 2024, Toronto, Canada |
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Changes in lipid metabolism in C. elegans resistant to ivermectinThe Hydra Helminth conference, Parasitic Helminths New perspectives in Biology and infection, Sep 2024, Hydra, Greece |
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Filarial DAF-12 sense the host serum to resume iL3 development during infectionLes Avancées Scientifiques de la Recherche Biomédicale Toulousaine, SFR-Biologie et Biotechnologie pour la Santé (B2S), Nov 2024, Toulouse, France |
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Comparative transcriptomic analysis in the Caenorhabditis elegans parasite model: impact of NHR-813èmes journées du CaPF, Consortium Antiparasitaire et Antifongique, May 2024, Toulouse, France |
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O75 | Pharmacodynamic and phenotypic evaluation of eprinomectin resistant Haemonchus isolates from French dairy sheep farms15th International Congress of the European Association for Veterinary Pharmacology and Toxicology, European Association of Veterinary Pharmacology and Toxicology (EAVPT), Jul 2023, Bruges, Belgium. pp.65-65, ⟨10.1111/jvp.13241⟩ |
Filarial DAF-12 sense Δ4-dafachronic acid in host serum to resume iL3 development during infectionMolecular Helminthology, Makedonka Mitreva; Phil Newmark; Mostafa Zamanian, Jun 2023, Madison, United States |
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Filarial DAF-12 sense Δ4-dafachronic acid in host serum to resume iL3 development during infection22nd Drug Design & Development Seminar (DDDS) 2022 of the German Society for Parasitology (DGP), University of Bern, DNDi & LMU Munich, Jul 2022, Munich, Germany |
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Filarial DAF-12 sense Δ4-dafachronic acid in host serum to resume iL3 development during infectionJournées d’Animation Scientifique du Département Santé Animale de l'INRAE, Oct 2022, Anglet, France |
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Anthelmintic Fluorescent drugs, new probes to detect anthelmintic resistance in the nematode Caenorhabditis elegansWAAVPT 2021, Jul 2021, Online, France |
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Filarial DAF-12 are activated by host serum steroids belonging to the cholestenoic acid cascade28th Conference of the World Association for the Advancement of Veterinary Parasitology (WAAVP), Jul 2021, Online, Ireland |
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The transcription factor NHR-8 is involved in ivermectin tolerance in the model nematode Caenorhabditis elegans and in the strongylid nematode Haemonchus contortusanthelmintics: Discovery to resistance, Jan 2018, Clearwater, United States |
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ABCB1 is involved in vitamin D intestinal efflux16. Fat Soluble Vitamins (FSV) congress, Société Française des Vitamines et Biofacteurs (SFVB). FRA., Mar 2017, Paris, France. 130 p |
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Discovery of a new factor involved in ivermectin tolerance in the model nematode Caenorhabditis elegans and in the strongylid nematode Haemonchus contortus.Molecular Helminthology: An Integrated Approach, Mar 2017, Cap Cod, United States |
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The transcription factor NHR-8 is involved in ivermectin tolerance in the model nematode <em>Caenorhabditis elegans</em> and in the strongylid nematode <em>Haemonchus contortus</em>26. International Conference of the World Association for the Advancement of Veterinary Parasitology (WAAVP 2017), The Malaysian Society of Parasitology & Tropical Medicine (MSPTM)., Sep 2017, Kuala Lumpur, Malaysia |
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Comparison of ivermectin and moxidectin resistance profiles in the nematode Caenorhabditis elegansInternational Conference of the World Association for the Advancement of Veterinary Parasitology (WAAVP 2015), Aug 2015, Liverpool, United Kingdom |
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Comparative pharmacodynamics and pharmacokinetics of moxidectin and ivermectin endectocides: a brief update12. International Congress of the European Association for Veterinary Pharmacology and Toxicology (EAVPT 2012), Jul 2012, Noordwijkerhout, Netherlands. 182 p |
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Chronic administration of ivermectin leads to a decrease of its concentration in the host12. International Congress of the European Association for Veterinary Pharmacology and Toxicology (EAVPT 2012), Jul 2012, Noordwijkerhout, Netherlands. 182 p |
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Differential neurotoxicity of ivermectin and moxidectin in mammals12. International Congress of the European Association for Veterinary Pharmacology and Toxicology (EAVPT 2012), Jul 2012, Noordwijkerhout, Netherlands. 182 p |
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Interaction of anthelminthics with ABC transportersSymposium on Membrane Ion Channels in Helminth Parasites, Resistance and Site of Action for Anthelmintics, Saisissez le nom du laboratoire, du service ou du département., Ville service., Dec 2011 |
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Optimizing anthelmintic combinations to counter anthelmintic resistanceConference of the World Association for the Advancement of Veterinary Parasitology, Saisissez le nom du laboratoire, du service ou du département., Ville service., Aug 2011, Buenos Aires, Argentina |
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Influence of obesity on the pharmacokinetics of anthelmintic macrocyclic lactones in dogs11th International congress of the European Association for Veterinary Pharmacology and Toxicology, 2009, Leipzig, Germany |
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WP6 - Control of P-glycoprotein (Pgp) in both host and parasites for an improvement of anthelmintic treatment.PARASOL - Sixth framework programme of the E.U. (Project FOOD-CT-2005-022851) - Novel solutions for the sustainable control of nematodes in ruminants, 2009, Edinburgh, United Kingdom. n.p |
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Disposition of eprinomectin in P-gp deficient mice: a comparison with ivermectin and moxidectin22nd World Association for the Advancement of Veterinary Parasitology Conference - WAAVP 2009, 2009, Calgary, Canada. pp.Inconnu |
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The anthelmintic ivermectin: a substrate of Breast-Cancer Resistant Protein (BCRP)22nd World Association for the Advancement of Veterinary Parasitology Conference - WAAVP 2009, 2009, Calgary, Canada. pp.Inconnu |
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Pharmacocinétique de l'éprinomectine chez les souris déficientes en P-gp : comparaison avec l'ivermectine et la moxidectineJournées d’Animation Scientifique du Département Santé Animale, 2009, Port d'Albret, France. pp.Inconnu |
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Interaction of macrocyclic lactones (MLs) with multidrug resistance transporters21st International Conference of the World Association for the Advancement of Veterinary Parasitology (WAAVP), 2007, Ghent, Belgium. pp.Inconnu |
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Investigations into the effects of p-glycoprotein and/or cytochrom P450 inhibitors on the phenotype responses of various developmental stages of ovine nematodes21st International Conference of the World Association for the Advancement of Veterinary Parasitology (WAAVP), 2007, Ghent, Belgium. pp.Inconnu |
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Rôle des ABC transporteurs dans le devenir des lactones macrocycliques dans l'organismeJournées francophones sur les transporteurs ABC, 2006, Paris, France. pp.Inconnu |
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Differences between ivermectin and moxidectin related to their affinities for multidrug resistance proteins (MRP1, 2 and 3)10e Congrès international de l’EAVPT, 2006, Turin, Italy. pp.Inconnu |
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Interaction of MLs with ABC transportersInvited by SOLVO Biotechnology, 2006, Budapest, Hungary. pp.Inconnu |
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Differences between ivermectin and moxidectin related to their affinities for multidrug resistance proteins (MRP1, 2, and 3)Inconnu, 2006, pp.Inconnu |
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Influence of anthelmintic drugs on P-glycoprotein transport activity in mdr1-LLC-PK1 cellsEAVPT, 2006, Turin, Italy. pp.Inconnu |
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The role of drug transporters in the disposition of milbemycins and avermectinsEAVPT, 2006, Turin, Italy. pp.Inconnu |
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Influence of hypercholesterolemia on disposition of moxidectin in a rabbit modelEUFEPS Conferences 3rd World Conference on Drug Absorption Transport and delivery, 2004, Barcelona, Spain. pp.Inconnu |
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Influence of the macrocyclic lactones on the P-glycoprotein function on P-gp overexpressing cellsEuropean Federation for Pharmaceutical Sciences Conference, 2004, Copenhagen, Denmark. pp.Inconnu |
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Hypodermosis control : determination of dose and route of administration of ivermectin microdosis to goatINCO Project nICA42000-30036 meeting, 2004, Shangai, China. pp.Inconnu |
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Eprinomectin in dairy goats : assessment of an optimal dosage8th International Conference on Goats, 2004, Pretoria, South Africa. pp.Inconnu |
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Improvement of ML's treatment by control of P-glycoprotein in the hostCOST - B16, 2004, Paris, France. pp.Inconnu |
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Chemotherapy improvement for hypodermosisINCO Project nICA42000-30036 meeting, 2004, Shangai, China. pp.Inconnu |
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Effect of route of administration and formulation on ivermectin bioavailability in Chinese cattleINCO Project nICA42000-30036 meeting, 2004, Shangai, China. pp.Inconnu |
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Intestinal lymphatic transport of moxidectin in conscious lymph duct-cannulated dogsEUFEPS Conferences 3rd World Conference on Drug Absorption Transport and delivery, 2004, Barcelona, Spain. pp.Inconnu |
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Role of the P-glycoprotein in the cellular eflux of macrocyclic lactones : influence of interfering agents9th EAVPT Congress, 2003, Lisbon, Portugal. pp.Inconnu |
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Binding of ivermectin and moxidectin to the plasma lipoproteins9th EAVPT Congress, 2003, Lisbon, Portugal. pp.Inconnu |
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Putative prediction of macrocyclic lactones in vivo-disposition using an original pharmacological parameter [Vp50] obtained from transport experiments in P-glycoprotein-expressing cells19th International Conference of the World Association for the Advancement of Veterinary Parasitology (WAAVP), 2003, New Orleans, United States. pp.Inconnu |
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Use of reversing agents of P-glycoprotein to increase the systematic availability of macrocyclic lactones : a promising tool19th International Conference of the World Association for the Advancement of Veterinary Parasitology, 2003, New Orleans, United States. pp.Inconnu |
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Larval motility assay using WMicrotracker™: a high throughput test to discriminate between resistance and susceptibility to anthelmintic drugs in nematodes2025 |
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Visite des bassins instrumentés « Olivier de Serres » de l’OHMCVJournées de l’Infrastructure de Recherche OZCAR, 2022 |
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Antiparasitaires : homme et animal, même combat !2020 |
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Deux mutations rares chez l'homme responsables de la toxicité du traitement contre la gâle2020 |
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Le contrôle du varron par l'ivermectine : éradication de l’hypodermose bovine[Rapport de recherche] 1396, INRAE. 2021, pp.17 |
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Ecotoxicity of antiparasitics: optimization of the use of pharmaceutical forms of ivermectin and its analogues[Rapport de recherche] ASI0001393, INRAE. 2021, pp.20 |
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Création de tomates de qualité pour le frais et l’industrie : F1 GARANCE et F1 TERRADOU[Rapport Technique] INRA. 2015 |