Antoine Huguet

Documents

Publications

Biofilm-driven LPS remodeling and colanic acid overproduction mediate biocide adaptation and antibiotic cross-resistance in E. coli

Raphaël Charron , Pierre Lemée , Thibaut Léger , Léonie Pigeon , Marine Boulanger et al.

npj Antimicrobials and Resistance, In press, ⟨10.1038/s44259-026-00224-5⟩

Article dans une revue anses-05701046v1

Strain-dependent emergence of aminoglycoside resistance in Escherichia coli biofilms

Raphaël Charron , Pierre Lemée , Antoine Huguet , Ornella Minlong , Marine Boulanger et al.

Biofilm, 2025, 9, pp.100273. ⟨10.1016/j.bioflm.2025.100273⟩

Article dans une revue hal-04993522v1

Combined in silico and in vitro approaches to identify P‐glycoprotein‐inhibiting pesticides

Nelly Guéniche , Zeineb Lakehal , Denis Habauzit , Arnaud Bruyère , Olivier Fardel et al.

Journal of Biochemical and Molecular Toxicology, 2024, 38 (1), pp.e23588. ⟨10.1002/jbt.23588⟩

Article dans une revue anses-04311433v1

Polyhexamethylene biguanide promotes adaptive crossresistance to gentamicin in Escherichia coli biofilms

Raphaël Charron , Pierre Lemée , Antoine Huguet , Ornella Minlong , Marine Boulanger et al.

Frontiers in Cellular and Infection Microbiology, 2023, 13 (1324991.), ⟨10.3389/fcimb.2023.1324991⟩

Article dans une revue hal-04334478v1

Co-culture model of Caco-2/HT29-MTX cells: a promising tool for investigation of phycotoxins toxicity on the intestinal barrier

Océane Reale , Antoine Huguet , Valérie Fessard

Chemosphere, 2021, 273, pp.128497. ⟨10.1016/j.chemosphere.2020.128497⟩

Article dans une revue anses-02958751v1

Comparative in silico prediction of P-glycoprotein-mediated transport for 2010-2020 US FDA-approved drugs using six Web-tools

Nelly Gueniche , Antoine Huguet , Arnaud Bruyere , Denis Habauzit , Ludovic Le Hegarat et al.

Biopharmaceutics and Drug Disposition, 2021, 42 (8), pp.393-398. ⟨10.1002/bdd.2299⟩

Article dans une revue hal-03341369v1

Role of enteric glial cells in the toxicity of phycotoxins: Investigation with a tri-culture intestinal cell model

Océane Reale , Dorina Bodi , Antoine Huguet , Valérie Fessard

Toxicology Letters, 2021, 351, pp.89-98. ⟨10.1016/j.toxlet.2021.08.013⟩

Article dans une revue anses-03378478v1

Permeability of the Cyanotoxin Microcystin-RR across a Caco-2 Cells Monolayer

Jérôme Henri , Rachelle Lanceleur , Jean-Michel Delmas , Valérie Fessard , Antoine Huguet

Toxins, 2021, 13 (3), pp.178. ⟨10.3390/toxins13030178⟩

Article dans une revue anses-03266193v1

Differential interactions of carbamate pesticides with drug transporters

Nelly Gueniche , Arnaud Bruyère , Mélanie Ringeval , Elodie Jouan , Antoine Huguet et al.

Xenobiotica, 2020, 50 (11), pp.1380-1392. ⟨10.1080/00498254.2020.1771473⟩

Article dans une revue anses-02626126v1

Differences in Toxic Response Induced by Three Variants of the Diarrheic Shellfish Poisoning Phycotoxins in Human Intestinal Epithelial Caco-2 Cells

Antoine Huguet , Olivia Drapeau , Fanny Rousselet , Hélène Quenault , Valérie Fessard

Toxins, 2020, 12 (12), pp.783. ⟨10.3390/toxins12120783⟩

Article dans une revue anses-03051663v1

Novel Insights on the Toxicity of Phycotoxins on the Gut through the Targeting of Enteric Glial Cells

Océane Reale , Antoine Huguet , Valérie Fessard

Marine drugs, 2019, 17 (7), pp.429. ⟨10.3390/md17070429⟩

Article dans une revue anses-02348860v1

Metabolism of the lipophilic phycotoxin 13-Desmethylspirolide C using human and rat in vitro liver models

Jimmy H Alarcan , Estelle Dubreil-Cheneau , Antoine H Huguet , Romulo Araoz , Françoise Brée et al.

Toxicology Letters, 2019, 307, pp.17-25. ⟨10.1016/j.toxlet.2019.02.012⟩

Article dans une revue anses-02083152v1

Identification of key pathways involved in the toxic response of the cyanobacterial toxin cylindrospermopsin in human hepatic HepaRG cells

Antoine Huguet , Rachelle Lanceleur , Hélène Quenault , Ludovic Le Hegarat , Valérie Fessard

Toxicology in Vitro, 2019, 58, pp.69-77. ⟨10.1016/j.tiv.2019.03.023⟩

Article dans une revue anses-02100344v1

Metabolism of the Marine Phycotoxin PTX-2 and Its Effects on Hepatic Xenobiotic Metabolism: Activation of Nuclear Receptors and Modulation of the Phase I Cytochrome P450

Jimmy H Alarcan , Estelle Dubreil-Chéneau , Antoine H Huguet , Dominique Hurtaud-Pessel , Stefanie Hessel-Pras et al.

Toxins, 2017, 9 (7), pp.673 - 673. ⟨10.1016/j.ab.2006.04.046⟩

Article dans une revue anses-01570019v1

Modulation of chromatin remodelling induced by the freshwater cyanotoxin cylindrospermopsin in human intestinal caco-2 cells.

Antoine Huguet , Aurélie Hatton , Romain Villot , Hélène Quenault , Yannick Blanchard et al.

PLoS ONE, 2014, 9 (6), pp.e99121. ⟨10.1371/journal.pone.0099121⟩

Article dans une revue hal-01025934v1

Low in vitro permeability of the cyanotoxin microcystin-LR across a Caco-2 monolayer: With identification of the limiting factors using modelling

Jérôme Henri , Antoine Huguet , Jean-Michel Delmas , Aurore Besson , Pascal Sanders et al.

Toxicon, 2014, pp.1-11. ⟨10.1016/j.toxicon.2014.07.023⟩

Article dans une revue istex hal-01076975v1

Permeability of dihydro- and cysteine-brevetoxin metabolites across a Caco-2 cell monolayer

Jérôme Henri , Ta Leighfield , Rachelle Lanceleur , Antoine Huguet , Js Ramsdell et al.

Harmful Algae, 2014, 32, pp.22-26. ⟨10.1016/j.hal.2013.11.007⟩

Article dans une revue istex hal-00998117v1

Comparative Cytotoxicity, Oxidative Stress, and Cytokine Secretion Induced by Two Cyanotoxin Variants, Microcystin LR and RR, in Human Intestinal Caco-2 Cells.

Antoine Huguet , Jérôme Henri , Mélanie Petitpas , Kevin Hogeveen , Valérie Fessard

Journal of Biochemical and Molecular Toxicology, 2013, 27 (5), pp.253-258. ⟨10.1002/jbt.21482⟩

Article dans une revue istex hal-00815224v1

Resistance in Escherichia coli: variable contribution of efflux pumps with respect to different fluoroquinolones.

Antoine Huguet , J. Pensec , Christophe Soumet

Journal of Applied Microbiology, 2013, epub ahead of print. ⟨10.1111/jam.12156⟩

Article dans une revue hal-00795561v1

Transcriptomic comparison of cyanotoxin variants in a human intestinal model revealed major differences in oxidative stress response: Effects of MC-RR and MC-LR on Caco-2 cells.

Perrine Zeller , Hélène Quenault , Antoine Huguet , Yannick Blanchard , Valérie Fessard

Ecotoxicology and Environmental Safety, 2012, epub ahead of print. ⟨10.1016/j.ecoenv.2012.05.001⟩

Article dans une revue istex hal-00712218v1

Improvement of growth performance and sanitary status of weaned piglets fed a bovine colostrum-supplemented diet

Antoine Huguet , Jean Le Dividich , Isabelle Luron Le Huërou-Luron

Journal of Animal Science, 2012, 90 (5), pp.1513-1520. ⟨10.2527/jas.2011-3941⟩

Article dans une revue hal-02647992v1

Defatted bovine colostrum-supplemented diet around weaning improves exocrine pancreatic secretion by means of volume, digestive enzymes and antibacterial activity

Antoine Huguet , Gérard Savary , Eric Bobillier-Chaumont , Isabelle Luron Le Huërou-Luron

Pancreas, 2009, 38 (3), pp.303-308. ⟨10.1097/MPA.0b013e318192eb83⟩

Article dans une revue hal-02660328v1

Influence of bovine colostrum on restoration of intestinal mucosa in weaned piglets

Antoine Huguet , Laurence Le Normand , Jacques Fauquant , Bertrand Kaeffer , Isabelle Luron

Livestock Science, 2007, 108 (1-3), pp.20-22. ⟨10.1016/j.livsci.2007.01.009⟩

Article dans une revue istex hal-01454003v1

Effects of a bovine colostrum-supplemented diet on some gut parameters in weaned piglets

Antoine Huguet , Bernard Sève , Jean Le Dividitch , Isabelle Luron Le Huërou-Luron

Reproduction Nutrition Development, 2006, 46, pp.167-178

Article dans une revue hal-02655380v1

Effects of level of feed intake on pancreatic exocrine secretions during the early postweaning period in piglets

Antoine Huguet , Gérard Savary , Eric Bobillier-Chaumont , Yves Lebreton , Isabelle Luron Le Huërou-Luron

Journal of Animal Science, 2006, 84 (11), pp.2965-2972

Article dans une revue hal-02664654v1

E. coli biofilm adaptation to biocides and impact on antibiotic resistance

Raphaël Charron , Pierre Lemée , Patricia Legrandois , Paméla Houée , Thibaut Leger et al.

Journées Scientifiques et Doctorales de l'ANSES 2024, Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail, Oct 2024, Maisons-Alfort, France

Communication dans un congrès hal-04968985v1

Adaptation to widely used biocide active susbtances selects for rifampicin resistance in E. coli biofilms

Raphaël Charron , Marine Boulanger , Pierre Lemée , Ornella Minlong , Paméla Houée et al.

Journées Scientifiques de l'école doctorale 2024, Ecole doctorale Sciences de la vie et de la Santé - ED637, Apr 2024, Saint-Malo, France

Communication dans un congrès hal-04969021v1

L’adaptation de biofilms de Escherichia coli aux biocides sélectionne des résistances à la rifampicine

Raphaël Charron , Pierre Lemée , Paméla Houée , Patricia Legrandois , Marine Boulanger et al.

Colloque du Réseau National Biofilms, Réseau National Biofilms, Nov 2024, Toulouse, France

Communication dans un congrès hal-04968999v1

Adaptation to widely used biocide active susbtances selects for rifampicin resistance in E. coli biofilms

Raphaël Charron , Pierre Lemée , Marine Boulanger , Ornella Minlong , Paméla Houée et al.

SurfSAFE Conference: Biofilm detection and control in the food industry, Sep 2023, Porto, Portugal. pp.1-82

Communication dans un congrès hal-04287649v1

Effects of dietary changes on the antibacterial activity of pancreatic juice in weaned piglets

Antoine Huguet , Gérard Savary , Eric Bobillier-Chaumont , Yves Lebreton , Isabelle Luron Le Huërou-Luron

10. International Symposium on Digestive Physiology in Pigs, May 2006, Vejle, Denmark

Communication dans un congrès hal-02752139v1

Biocides drive rifampicin cross-resistance in Escherichia coli biofilm

Raphaël Charron , Pierre Lemée , Marine Boulanger , Ornella Minlong , Paméla Houée et al.

Eurobiofilms 2024, Jun 2024, Copenhague, France

Poster de conférence hal-04968964v1

Adaptation to widely used biocide substances selects for rifampicin resistance in E. coli biofilms

Raphaël Charron , Pierre Lemee , Marine Boulanger , Ornella Minlong , Paméla Houée et al.

Société Française de Microbiologie 2023, Oct 2023, Rennes, France

Poster de conférence hal-04287793v1

Adaptation to widely used biocide substances selects for rifampicin resistance in E. coli biofilms

Raphaël Charron , Pierre Lemee , Marine Boulanger , Ornella Minlong , Paméla Houée et al.

Journées Scientifiques et Doctorales de l'ANSES, Oct 2023, Maisons-Alfort, France

Poster de conférence hal-04287692v1

Adaptation to widely used biocide substances selects for rifampicin resistance in E. coli biofilms

Raphaël Charron , Pierre Lemee , Marine Boulanger , Ornella Minlong , Paméla Houée et al.

FEMS2023 (Federation of European Microbiological Societies). 10th congress of European microbiologists, Jul 2023, Hambourg, Germany. , 2023

Poster de conférence hal-04287706v1

Microcystin-LR transfer through the in vitro intestinal barrier of caco-2 cells

Jérôme Henri , Antoine Huguet , Aurore Besson , Jean-Michel Delmas , Valérie Fessard

The 8th international conference on toxic cyanobacteria, Aug 2010, Istanbul, Turkey

Poster de conférence anses-05479973v1

EFFECTS OF MICROCYSTIN LR ON THE INTEGRITY OF THE IN VITRO CACO-2 INTESTINAL BARRIER MODEL

Antoine Huguet , Jérôme Henri , Aurore Besson , Valérie Fessard

EUSAAT (European society for alternatives to animal testing), Sep 2010, Linz, Austria

Poster de conférence anses-05479948v1

Effets d'un aliment supplémentaire en colostrum bovin sur le système digestif du porcelet au sevrage

Antoine Huguet

Sciences du Vivant [q-bio]. Ecole Nationale Supérieure Agronomique de Rennes, 2006. Français. ⟨NNT : ⟩

Thèse tel-02822906v1

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