AB

Arnaud Billet

Maître de conférences BTSB EA7417 INU Champollion
26
Documents

Publications

Publications

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Adaptive trade-offs between vertebrate defence and insect predation drive Amazonian ant venom evolution

Axel Touchard , Samuel D Robinson , Hadrien Lalagüe , Steven Ascoët , Arnaud Billet et al.
Proceedings of the Royal Society B: Biological Sciences, 2024, 291 (2035), ⟨10.1098/rspb.2024.2184⟩
Article dans une revue hal-04795576 v1

Isolation, NMR Characterization, and Bioactivity of a Flavonoid Triglycoside from Anthyllis henoniana Stems: Antioxidant and Antiproliferative Effects on MDA-MB-231 Breast Cancer Cells

Amani Ayachi , Guillaume Boy , Sonda Samet , Nathan Téné , Bouthaina Bouzayani et al.
Antioxidants , 2024, 13 (7), pp.793. ⟨10.3390/antiox13070793⟩
Article dans une revue hal-04635159 v1
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The mechanism underlying toxicity of a venom peptide against insects reveals how ants are master at disrupting membranes

Steven Ascoët , Axel Touchard , Nathan Téné , Benjamin Lefranc , Jérôme Leprince et al.
iScience, 2023, 26 (3), pp.106157. ⟨10.1016/j.isci.2023.106157⟩
Article dans une revue hal-04071274 v1
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Discovery of an Insect Neuroactive Helix Ring Peptide from Ant Venom

Valentine Barassé , Laurence Jouvensal , Guillaume Boy , Arnaud Billet , Steven Ascoët et al.
Toxins, 2023, 15 (10), pp.600. ⟨10.3390/toxins15100600⟩
Article dans une revue hal-04390519 v1
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The multi-faceted nature of 15 CFTR exonic variations: Impact on their functional classification and perspectives for therapy

Anne Bergougnoux , A. Billet , C. Ka , M. Heller , F. Degrugillier et al.
Journal of Cystic Fibrosis, 2022, ⟨10.1016/j.jcf.2022.12.003⟩
Article dans une revue hal-03913493 v1
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The rescue of F508del-CFTR by elexacaftor/tezacaftor/ivacaftor (Trikafta) in human airway epithelial cells is underestimated due to the presence of ivacaftor

Frédéric Becq , Sandra Mirval , Thomas Carrez , Manuella Lévêque , Arnaud Billet et al.
European Respiratory Journal, 2022, 59 (2), pp.2100671. ⟨10.1183/13993003.00671-2021⟩
Article dans une revue hal-04352015 v1
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Functional and Pharmacological Characterization of the Rare CFTR Mutation W361R

Arnaud Billet , Ahmad Elbahnsi , Mathilde Jollivet-Souchet , Brice Hoffmann , Jean-Paul Mornon et al.
Frontiers in Pharmacology, 2020, 11, ⟨10.3389/fphar.2020.00295⟩
Article dans une revue hal-02557014 v1
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Targeting different binding sites in the CFTR structures allows to synergistically potentiate channel activity

Lionel Froux , Ahmad Elbahnsi , Benjamin Boucherle , Arnaud Billet , Nesrine Baatallah et al.
European Journal of Medicinal Chemistry, 2020, 190, pp.112116. ⟨10.1016/j.ejmech.2020.112116⟩
Article dans une revue hal-02924784 v1
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Pendrin mediates bicarbonate secretion and enhances CFTR function in airway surface epithelia

Dusik Kim , Junwei Huang , Arnaud Billet , Asmahan Abu-Arish , Julie Goepp et al.
American Journal of Respiratory Cell and Molecular Biology, 2019, 60 (6), pp.705-716. ⟨10.1165/rcmb.2018-0158OC⟩
Article dans une revue hal-03145546 v1

Modulating the cystic fibrosis transmembrane regulator and the development of new precision drugs

Lionel Froux , Arnaud Billet , Frédéric Becq
Expert Review of Precision Medicine and Drug Development, 2018, 3 (6), pp.357-370. ⟨10.1080/23808993.2018.1547109⟩
Article dans une revue hal-03192898 v1
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Development of Automated Patch Clamp Technique to Investigate CFTR Chloride Channel Function

Arnaud Billet , Lionel Froux , John Hanrahan , Frederic Becq
Frontiers in Pharmacology, 2017, 8, pp.195. ⟨10.3389/fphar.2017.00195⟩
Article dans une revue hal-03191777 v1

Low free drug concentration prevents inhibition of F508del CFTR functional expression by the potentiator VX-770 (ivacaftor)

Elizabeth Matthes , Julie Goepp , Graeme Carlile , Yishan Luo , Kurt Dejgaard et al.
British Journal of Pharmacology, 2016, 173 (3), pp.459-470. ⟨10.1111/bph.13365⟩
Article dans une revue hal-03193045 v1

Potential sites of CFTR activation by tyrosine kinases

Arnaud Billet , Yanlin Jia , Timothy Jensen , Yue-Xian Hou , Xiu-Bao Chang et al.
Channels, 2016, 10 (3), pp.247-251. ⟨10.1080/19336950.2015.1126010⟩
Article dans une revue hal-03192938 v1

The dual phosphodiesterase 3 and 4 inhibitor RPL554 stimulates CFTR and ciliary beating in primary cultures of bronchial epithelia

Mark Turner , Elizabeth Matthes , Arnaud Billet , Amy Ferguson , David Thomas et al.
American Journal of Physiology - Lung Cellular and Molecular Physiology, 2016, 310 (1), pp.L59-L70. ⟨10.1152/ajplung.00324.2015⟩
Article dans une revue hal-03193027 v1

Regulation of the cystic fibrosis transmembrane conductance regulator anion channel by tyrosine phosphorylation

Arnaud Billet , John W Hanrahan
FASEB Journal, 2015, 29 (9), pp.3945-3953. ⟨10.1096/fj.15-273151⟩
Article dans une revue hal-03192145 v1

Role of Tyrosine Phosphorylation in the Muscarinic Activation of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)

Arnaud Billet , Yishan Luo , Haouaria Balghi , John Hanrahan
Journal of Biological Chemistry, In press, 288 (30), pp.21815-21823. ⟨10.1074/jbc.M113.479360⟩
Article dans une revue hal-03191691 v1

CFTR: Effect of ICL2 and ICL4 amino acids in close spatial proximity on the current properties of the channel

Arnaud Billet , Jean-Paul Mornon , Mathilde Jollivet , Pierre Lehn , Isabelle Callebaut et al.
Journal of Cystic Fibrosis, 2013, 12, pp.737-745. ⟨10.1016/j.jcf.2013.02.002⟩
Article dans une revue istex hal-00907930 v1

The secret life of CFTR as a calcium-activated chloride channel

Arnaud Billet , John W Hanrahan
The Journal of Physiology, 2013, 591 (21), pp.5273-5278. ⟨10.1113/jphysiol.2013.261909⟩
Article dans une revue hal-03192129 v1
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Stimulation of wild-type, F508del- and G551D-CFTR chloride channels by non-toxic modified pyrrolo[2,3-b]pyrazine derivatives

Luc Dannhoffer , Arnaud Billet , Mathilde Jollivet-Souchet , Patricia Melin-Heschel , Christelle Faveau et al.
Frontiers in Pharmacology, 2011, 2, ⟨10.3389/fphar.2011.00048⟩
Article dans une revue hal-03192023 v1

Understanding nucleotide binding and CFTR ion channel gating: how many cycles?

Frédéric Becq , Arnaud Billet
Expert Review of Respiratory Medicine, 2010, 4 (4), pp.451-4. ⟨10.1586/ers.10.47⟩
Article dans une revue hal-00561612 v1

Identification of a novel water-soluble activator of wild-type and F508del CFTR: GPact-11a.

J. Bertrand , B. Boucherle , A. Billet , P. Melin-Heschel , L. Dannhoffer et al.
European Respiratory Journal, 2010, 36 (2), pp.311-22. ⟨10.1183/09031936.00122509⟩
Article dans une revue hal-00559199 v1
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C terminus of nucleotide binding domain 1 contains critical features for cystic fibrosis transmembrane conductance regulator trafficking and activation.

Arnaud Billet , Patricia Melin , Mathilde Jollivet , Jean-Paul Mornon , Isabelle Callebaut et al.
Journal of Biological Chemistry, 2010, 285 (29), pp.22132-40. ⟨10.1074/jbc.M110.120683⟩
Article dans une revue hal-00582442 v1