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Béatrice Mandon-Pépin

123
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Presentation

***Différenciation des Gonades et ses Perturbations*** **UMR 1198 BREED - Biologie de la Reproduction, Environnement, Epigénétique et Développement** Université Paris-Saclay, UVSQ, INRAE, BREED, 78350, Jouy-en-Josas, France
DEA d'Endocrinologie - Université Paris VI Doctorat d'Université, Spécialité: Endocrinologie - Université Paris VI Diplôme Universitaire "Création, analyse et valorisation des données -omiques" - Paris-Diderot

Publications

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Bisphenol A and bisphenol S both disrupt ovine granulosa cell steroidogenesis but through different molecular pathways

Ophélie Téteau , Anaïs Vitorino Carvalho , Pascal Papillier , Béatrice Mandon-Pepin , Luc Jouneau et al.
Journal of Ovarian Research, 2023, 16 (1), pp.30. ⟨10.1186/s13048-023-01114-4⟩
Journal articles hal-03972669v1
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Whole-exome sequencing in patients with maturation arrest: a potential additional diagnostic tool for prevention of recurrent negative testicular sperm extraction outcomes

F Ghieh , A Barbotin , N Swierkowski-Blanchard , C Leroy , J Fortemps et al.
Human Reproduction, 2022, 37 (6), pp. 1334-1350. ⟨10.1093/humrep/deac057⟩
Journal articles hal-03657553v1
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Fetal estrogens are not involved in sex determination but critical for early ovarian differentiation in rabbits

Geneviève Jolivet , Nathalie Daniel-Carlier , Erwana Harscoët , Eloïse Airaud , Aurélie Dewaele et al.
Endocrinology, 2022, 163 (1), ⟨10.1210/endocr/bqab210⟩
Journal articles hal-03370216v1
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Ovine fetal testis stage-specific sensitivity to environmental chemical mixtures

Richard Lea , Béatrice Mandon-Pepin , Benoit Loup , Elodie Poumerol , Luc Jouneau et al.
Reproduction, 2022, 163 (2), pp.119-131. ⟨10.1530/REP-21-0235⟩
Journal articles hal-03560775v1

BPA disrupts meiosis I in oogonia by acting on pathways including cell cycle regulation, meiosis initiation and spindle assembly

Benoit Loup , Elodie Poumerol , Luc Jouneau , Paul A Fowler , Corinne Cotinot et al.
Reproductive Toxicology, 2022, 111, p. 166-177. ⟨10.1016/j.reprotox.2022.06.001⟩
Journal articles hal-03692951v1

Cryptic splice site poisoning and meiotic arrest caused by a homozygous frameshift mutation in RBMXL2 : A case report

Farah Ghieh , Vincent Izard , Marine Poulain , Johanne Fortemps , Nadia Kazdar et al.
Andrologia, 2022, ⟨10.1111/and.14595⟩
Journal articles hal-03791691v1
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Will whole-genome sequencing become the first-line genetic analysis for male infertility in the near future?

Farah Ghieh , Anne-Laure Barbotin , Clara Leroy , François Marcelli , Nelly Swierkowsky-Blanchard et al.
Basic and clinical andrology, 2021, 31 (1), ⟨10.1186/s12610-021-00138-4⟩
Journal articles hal-03327919v1
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Structural and Functional Characterization of a Testicular Long Non-coding RNA (4930463O16Rik) Identified in the Meiotic Arrest of the Mouse Topaz1–/– Testes

Manon Chadourne , Elodie Poumerol , Luc Jouneau , Bruno Passet , Johan Castille et al.
Frontiers in Cell and Developmental Biology, 2021, 9, ⟨10.3389/fcell.2021.700290⟩
Journal articles hal-03298848v1
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Azoospermia and reciprocal translocations: should whole-exome sequencing be recommended?

Farah Ghieh , Anne-Laure Barbotin , Julie Prasivoravong , Sophie Ferlicot , Béatrice Mandon-Pepin et al.
Basic and clinical andrology, 2021, 31 (27), ⟨10.1186/s12610-021-00145-5⟩
Journal articles hal-03455754v1
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Human testis-expressed (TEX) genes: a review focused on spermatogenesis and male fertility

Hela Bellil , Farah Ghieh , Emeline Hermel , Béatrice Mandon-Pepin , François Vialard et al.
Basic and clinical andrology, 2021, 31 (1), ⟨10.1186/s12610-021-00127-7⟩
Journal articles hal-03216070v1

Male Infertility and Genetic screening: Guidelines in 2021

Ghieh Farah , Béatrice Mandon-Pepin , François Vialard
Archives of Clinical and Biomedical Research, 2020, 05 (01), ⟨10.26502/acbr.50170151⟩
Journal articles hal-03202224v1

Prenatal cannabinoid exposure alters the ovarian reserve in adult offspring of rats

Pierre Castel , Magalie Barbier , Elodie Poumerol , Béatrice Mandon-Pepin , Virginie Tassistro et al.
Archives of Toxicology, 2020, 94 (12), pp.4131-4141. ⟨10.1007/s00204-020-02877-1⟩
Journal articles hal-02955179v1
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Genetic defects in human azoospermia

Farah Ghieh , Valerie Mitchell , Béatrice Mandon-Pepin , François Vialard
Basic and clinical andrology, 2019, 29 (1), pp.4. ⟨10.1186/s12610-019-0086-6⟩
Journal articles hal-02315267v1
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Long-term exposure to chemicals in sewage sludge fertilizer alters liver lipid content in females and cancer marker expression in males

Panagiotis Filis , Natasha Walker , Linda Robertson , Emily Eaton-Turner , Lauma Ramona et al.
Environment International, 2019, 124, pp.98-108. ⟨10.1016/j.envint.2019.01.003⟩
Journal articles hal-02628862v1
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Des souris et des femmes : une ovogenèse fœtale similaire ?

Clara Gobe , Béatrice Mandon-Pepin
Médecine de la Reproduction, 2019, 21 (2), pp.111-126. ⟨10.1684/mte.2019.0746⟩
Journal articles hal-02360556v1
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The fetal ovary exhibits temporal sensitivity to a ‘real-life’ mixture of environmental chemicals

Richard G. Lea , Maria R. Amezaga , Benoît Loup , Béatrice Mandon-Pepin , Agnes Stefansdottir et al.
Scientific Reports, 2016, 6, pp.1-13. ⟨10.1038/srep22279⟩
Journal articles hal-02641103v1

Timing of maternal exposure and foetal sex determine the effects of low-level chemical mixture exposure on the foetal neuroendocrine system in sheep

M. Bellingham , P.A. Fowler , E.S. Macdonald , Béatrice Mandon-Pepin , Corinne Cotinot et al.
Journal of Neuroendocrinology, 2016, 28 (12), ⟨10.1111/jne.12444⟩
Journal articles hal-02637982v1

TOPAZ1, a germ cell specific factor, is essential for male meiotic progression

Alix Luangpraseuth-Prosper , Elodie Lesueur , Luc Jouneau , Eric Pailhoux , Corinne Cotinot et al.
Developmental Biology, 2015, 406 (2), pp.158-171. ⟨10.1016/j.ydbio.2015.09.002⟩
Journal articles hal-02635577v1
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Spatio-temporal gene expression profiling during in vivo early ovarian folliculogenesis: integrated transcriptomic study and molecular signature of early follicular growth

Agnès Bonnet , Bertrand Servin , Philippe Mulsant , Béatrice Mandon-Pepin
PLoS ONE, 2015, 5 (November), pp.1-25. ⟨10.1371/journal.pone.0141482⟩
Journal articles hal-02634306v1

Maternal high-fat diet induces follicular atresia but does not affect fertility in adult rabbit offspring

Pauline Léveillé , Anne Couturier-Tarrade , Charlotte Dupont , Thibaut Larcher , Michèle Dahirel et al.
Journal of Developmental Origins of Health and Disease, 2014, 5 (2), pp.88-97. ⟨10.1017/S2040174414000014⟩
Journal articles hal-03609938v1

Exposure to chemical cocktails before or after conception - The effect of timing on ovarian development

Michelle M. Bellingham , Maria R. M. R. Amezaga , Béatrice Mandon-Pepin , Christopher J.B. C. J. Speers , Carol E. C. E. Kyle et al.
Molecular and Cellular Endocrinology, 2013, 376 (1-2), pp.156-172. ⟨10.1016/j.mce.2013.06.016⟩
Journal articles hal-01001415v1
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Dietary lipid and cholesterol induce ovarian dysfunction and abnormal LH response to stimulation in rabbits

Anne Gaël Cordier , Pauline Leveille , Charlotte Dupont , Anne Couturier-Tarrade , Olivier Picone et al.
PLoS ONE, 2013, 8 (5), pp.1-11. ⟨10.1371/journal.pone.0063101⟩
Journal articles hal-01004078v1

Peri-conceptional changes in maternal exposure to sewage sludge chemicals disturbs fetal thyroid gland development in sheep

Sabine Hombach-Klonisch , Adrian Danescu , Farhana Begum , Maria R. Amezaga , Stewart M. Rhind et al.
Molecular and Cellular Endocrinology, 2013, 367 (1-2), pp.98-108. ⟨10.1016/j.mce.2012.12.022⟩
Journal articles hal-01190430v1
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An overview of gene expression dynamics during early ovarian folliculogenesis: specificity of follicular compartments and bi-directional dialog

Agnès Bonnet , Cédric Cabau , Olivier Bouchez , Julien Sarry , Nathalie Marsaud et al.
BMC Genomics, 2013, 14 (december), pp.1-19. ⟨10.1186/1471-2164-14-904⟩
Journal articles hal-01019557v1

Mammalian ovary differentiation - A focus on female meiosis

Adrienne A. Baillet , Béatrice Mandon-Pepin
Molecular and Cellular Endocrinology, 2012, 356 (1-2), pp.13-23. ⟨10.1016/j.mce.2011.09.029⟩
Journal articles hal-01000904v1

Maternal environment and the reproductive function of the offspring

Charlotte Dupont , Anne Gaël Cordier , Claudine Junien , Béatrice Mandon-Pepin , Rachel Levy et al.
Theriogenology, 2012, 78 (7), pp.1405-1414. ⟨10.1016/j.theriogenology.2012.06.016⟩
Journal articles hal-01190203v1

Foetal and post-natal exposure of sheep to sewage sludge chemicals disrupts sperm production in adulthood in a subset of animals

Michelle Bellingham , C. Mckinnell , P.A. Fowler , M.R. Amezaga , Zhongkai Zhang et al.
International Journal of Andrology, 2012, 35 (3), pp.317-329. ⟨10.1111/j.1365-2605.2011.01234.x⟩
Journal articles hal-01191280v1
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TOPAZ1, a novel germ cell-specific expressed gene conserved during evolution across vertebrates

Adrienne A. Baillet , Ronan R. Le Bouffant , Jean Nicolas J. N. Volff , Alix A. Luangpraseuth , Elodie Poumerol et al.
PLoS ONE, 2011, 6 (11), pp.1-15. ⟨10.1371/journal.pone.0026950⟩
Journal articles hal-01000215v1
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Transcriptome profiling of sheep granulosa cells and oocytes during early follicular development obtained by laser capture microdissection.

Agnes Bonnet , Claudia Bevilacqua , Francis Benne , Loys Bodin , Corinne Cotinot et al.
BMC Genomics, 2011, 12 (august), pp.417. ⟨10.1186/1471-2164-12-417⟩
Journal articles hal-00842681v1

First evidence of Bone Morphogenetic Protein 1 expression and activity in sheep ovarian follicles

E. Canty-Laird , Gwenn-Aël Carre , Béatrice Mandon-Pepin , K.E. Kadler , Stéphane Fabre et al.
Biology of Reproduction, 2010, 83 (1), pp.138-146. ⟨10.1095/biolreprod.109.082115⟩
Journal articles hal-01136270v1

Effects of environmental pollutants on the reproduction and welfare of ruminants

S.M. Rhind , N. P. Evans , M. Bellingham , R.M. Sharpe , Corinne Cotinot et al.
Animal, 2010, 4 (7), pp.1227-1239. ⟨10.1017/S1751731110000595⟩
Journal articles hal-02668440v1

Maternal and fetal tissue accumulation of selected endocrine disrupting compounds (EDCs) following exposure to sewage sludge-treated pastures before or after conception

S.M. Rhind , C.E. Kyle , C. Mackie , L. Mcdonald , Zuochun Zhang et al.
Journal of Environmental Monitoring, 2010, 12 (8), pp.1582-1593. ⟨10.1039/c0em00009d⟩
Journal articles hal-02668388v1

Foetal hypothalamic and pituitary expression of gonadotrophin-releasing hormone and galanin systems is disturbed by exposure to sewage sludge chemicals via maternal ingestion

M. Bellingham , Paul Fowler , M. R. Amezaga , C. M. Whitelaw , S. M. Rhind et al.
Journal of Neuroendocrinology, 2010, 22 (6), pp.527-533. ⟨10.1111/j.1365-2826.2010.01974.x⟩
Journal articles hal-02668347v1
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Exposure to a complex cocktail of environmental endocrine-disrupting compounds disturbs the kisspeptin/GPR54 system in ovine hypothalamus and pituitary gland

Michelle Bellingham , Paul A. Fowler , Maria R. Amezaga , Stewart M. Rhind , Corinne Cotinot et al.
Environmental Health Perspectives, 2009, 177 (10), pp.1556-1562. ⟨10.1289/ehp.0900699⟩
Journal articles hal-02668264v1

Anomalies génétiques et infertilité masculine

François Vialard , Béatrice Mandon-Pepin , F. Pellestor , A. Ziyyat , M. Albert et al.
Andrologie, 2009, 19, pp.2-16
Journal articles hal-02656888v1

Attempt to rescue sex-reversal by transgenic expression of the PISRT1 gene in XX PIS-/- goats

Laurent Boulanger , Ayhan Kocer , Nathalie Daniel , Maëlle Pannetier , Patrick Chesné et al.
Sexual Development, 2008, 2, pp.142-151. ⟨10.1159/000143432⟩
Journal articles hal-01193505v1
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Identification of transcripts involved in meiosis and follicle formation during ovine ovary development

Adrienne Baillet , Béatrice Mandon-Pepin , Cédric Cabau , Elodie Poumerol , Eric Pailhoux et al.
BMC Genomics, 2008, 9 (436), 12p. ⟨10.1186/1471-2164-9-436⟩
Journal articles hal-02658492v1

Genetic investigation of four meiotic genes in women with premature ovarian failure

Béatrice Mandon-Pepin , Philippe Touraine , Frédérique Kuttenn , Céline Derbois , Agnes Rouxel et al.
European Journal of Endocrinology, 2008, 158, pp.107-115. ⟨10.1530/EJE-07-0400⟩
Journal articles hal-02659458v1
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Structural and functional analyses of the DMC1-M200V polymorphism found in the human population

Juri Hikiba , Kouji Hirota , Waturu Kagawa , Shukuko Ikawa , Takashi Kinebuchi et al.
Nucleic Acids Research, 2008, 36 (12), pp.4181-4190. ⟨10.1093/nar/gkn362⟩
Journal articles hal-02659900v1

FOXL2 actives P450 aromatase gene transcription: towards a better characterization of the early steps of mammalian ovarian development

Maëlle Pannetier , Stéphane Fabre , F. Batista , Ayhan Kocer , Lauriane Renault et al.
Journal of Molecular Endocrinology, 2006, 36 (3), pp.399-413
Journal articles hal-02661359v1

Molecular basis of bone morphogenetic protein-4 inhibitory action on progesterone secretion by ovine granulosa cells

A. Pierre , C. Pisselet , Joëlle Dupont , Béatrice Mandon-Pepin , Danielle Monniaux et al.
Journal of Molecular Endocrinology, 2004, 33, pp.805-817
Journal articles hal-02674170v1

Molecular aspects of female and male gonodal development in mammals

Maëlle Pannetier , Béatrice Mandon-Pepin , S. Copelli , Marc Fellous
Pediatric Endocrinology Reviews, 2004, 1 (3), pp.274-287
Journal articles hal-02670341v1

Expression profiles and chromosomal localization of genes controlling meiosis and follicular development in the sheep ovary

Béatrice Mandon-Pepin , A. Oustry-Vaiman , Brigitte Vigier , François Piumi , Edmond E. Cribiu et al.
Biology of Reproduction, 2003, 68, pp.985-995
Journal articles hal-02670627v1

Génétique et infertilité humaine : "une approche gènes candidats"

Béatrice Mandon-Pepin , C. Derbois , F. Matsuda , Corinne Cotinot , D.J. Wolgemuth et al.
Reproduction Humaine et Hormones, 2002, 15 (6), pp.390-394
Journal articles hal-02669393v1

Infertilité humaine : des gènes de méiose comme candidats potentiels

Béatrice Mandon-Pepin , C. Derbois , F. Matsuda , Corinne Cotinot , D.J. Wolgemuth et al.
Gynécologie Obstétrique & Fertilité, 2002, 30, pp.817-821
Journal articles hal-02674693v1

Extracellular matrix regulates ovine granulosa cell survival, proliferation and steroidogenesis: relationship between cell shape and function

Camille Huet , C. Pisselet , Béatrice Mandon-Pepin , Philippe Monget , Danielle Monniaux et al.
Journal of Endocrinology, 2001, 169, pp.347-360
Journal articles hal-02681251v1

Mammalian gonodal differentiation : the pig model

Eric Pailhoux , Béatrice Mandon-Pepin , Corinne Cotinot
Reproduction -Cambridge- Supplement-, 2001, 58, pp.65-80
Journal articles hal-02678865v1

L'atrésie folliculaire, un gaspillage programmé

Danielle Monniaux , Béatrice Mandon-Pepin , Philippe Monget
médecine/sciences, 1999, 15, pp.157-166
Journal articles hal-02698434v1

Mécanismes, régulations et manipulations de l'atrésie folliculaire

Danielle Monniaux , Camille Huet , C. Pisselet , Béatrice Mandon-Pepin , Philippe Monget et al.
Contraception Fertilité Sexualité, 1998, 26 (7-8), pp.528-535
Journal articles hal-02687781v1

La différenciation sexuelle des gonades et de l'appareil génital

Eric Pailhoux , Maëlle Pannetier , Béatrice Mandon-Pepin
La reproduction animale et humaine, Editions Quae, 751 p., 2014, Synthèses (Quae), 978-2-7592-2208-7
Book sections hal-02797379v1

A Journey Through Ovarian Cells Differenciation in Rabbits: From Genetic to Epigenetic mechanisms.

Namya Mellouk , Béatrice Mandon-Pepin , Luc Jouneau , Anne Aubert-Frambourg , Dominique Thepot Thépot et al.
The XXIX International Symposium Molecular and Physiological Aspects of Regulatory Processes, Oct 2022, Cracovie, Poland
Conference papers hal-03799180v1

DMRT1 is Required For Sex Determination in Rabbits

Emilie Dujardin , Marjolaine André , Aurélie Dewaele , Béatrice Mandon-Pepin , Namya Mellouk et al.
2nd European Symposium on Sex Determination in Vertebrates, Oct 2022, Presqu'île de Giens, France
Conference papers hal-03798961v1

DMRT1 is a Sex-Determining Gene in Rabbits

Emilie Dujardin , Namya Mellouk , Marjolaine André , Béatrice Mandon-Pepin , Aurélie Dewaele et al.
54th SSR Annual Meeting, Dec 2021, Saint-Louis, United States
Conference papers hal-03601143v1

Dynamique de l’épigénome des cellules germinales femelles lors de l’initiation de la méiose dans l’ovaire fœtal de lapin : Analyse des modifications post-traductionnelles des histones par CUT&RUN

Eugénie Canon , Namya Mellouk , Aurélie Dewaele , Béatrice Mandon-Pepin , Luc Jouneau et al.
EpiPHASE 6ème journée d'animation scientifique autour de l'épigénétique, Jun 2021, Lyon, France
Conference papers hal-03284634v1

DMRT1 is Required For Sex Determination in Rabbits

Emilie Dujardin , Namya Mellouk , Marjolaine André , Béatrice Mandon-Pepin , Aurélie Dewaele et al.
First Virtual International Symposium on Vertebrate Sex Determination, Oct 2021, kona, hawaii, United States
Conference papers hal-03367273v1

Caractérisation des trajectoires de différenciation des cellules germinales au cours de la différenciation de l'ovaire fœtal chez le lapin

Namya Mellouk , Béatrice Mandon-Pepin , Aurélie Dewaele , Luc Jouneau , Emilie Dujardin et al.
EpiPHASE 6ème journée d'animation scientifique autour de l'épigénétique, Jun 2021, Lyon, France
Conference papers hal-03284642v1
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Topaz1 suppression disrupts the expression of testicular long non-coding RNAs during murine spermatogenesis

Manon Chadourne , Elodie Poumerol , Bruno Passet , Luc Jouneau , Eric Pailhoux et al.
21st European Testis Workshop, May 2021, Virtual edition, Spain
Conference papers hal-03298411v1

Différenciation et reprogrammation épigénétique des cellules germinales mâles dans le testicule fœtal bovin

Marjolaine André , Béatrice Mandon-Pepin , Aurélie Allais-Bonnet , Hélène Jammes , Amélie Bonnet-Garnier et al.
EpiPHASE 6ème journée d'animation scientifique autour de l'épigénétique, Jun 2021, Lyon, France
Conference papers hal-03284625v1
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Intérêt de l’analyse chromosomique sur puce à ADN en cas de blocage de maturation méiotique testiculaire

Farah Ghieh , Valérie Mitchell , Marc Bailly , Vincent Izard , Béatrice Mandon-Pepin et al.
XXIV Colloque ACLF & XXVIII Colloque ATC, Association des Cytogénéticiens de Langue Française & Association des Technicien(ne)s en Cytogénétique., Sep 2018, Saint Malo, France
Conference papers hal-02790273v1

Reprogrammation de la méthylation de l’ADN des cellules germinales au cours du développement testiculaire chez Capra Hircus

Aurélie Allais-Bonnet , Béatrice Mandon-Pepin , Marjolaine André , Eric Pailhoux , Audrey Prézelin et al.
3. Journée de Séminaires du Département Phase sur l'Epigénétique EpiPhase, May 2017, Jouy-en-Josas, France. 1 p
Conference papers hal-01607860v1

Epigenetic reprogramming in the male germ line of ruminants

Béatrice Mandon-Pepin , Aurélie Allais-Bonnet , Marjolaine André , Pierre Calvel , Eli Sellem et al.
France-Japan Epigenetics Workshop 2017, ATouT. Com. FRA., Nov 2017, Paris, France
Conference papers hal-02791776v1

Endocrine disruptors and ovine reproductive development

Richard G. Lea , A. Byers , Michelle Bellingham , Corinne Cotinot , Neil Evans et al.
9. International Ruminant Reproduction Symposium, Society for the Study of Reproduction (SSR). USA., Aug 2014, Hokkaido, Japan. 632 p
Conference papers hal-02741122v1

Comparison of sheep foetal ovarian development after in vivo and in vitro exposure to DEHP/MEHP, PCBs (101+118) and a mixture of both

Béatrice Mandon-Pepin , Benoît Loup , Maria R. Amezaga , Richard G. Lea , Kevin D. Sinclair et al.
7. Copenhagen Workshop on Endocrine Disrupters, May 2013, Copenhague, Denmark. 1 p
Conference papers hal-01189846v1

Topaz1, un gène indispensable à la spermatogénèse et la fertilité mâle

Alix Luangpraseuth , Elodie Poumerol , Adrienne Baillet , Corinne Cotinot , Béatrice Mandon-Pepin et al.
5. Journées d'Animation Scientifique du département Phase (JAS Phase 2013), Oct 2013, Paris, France
Conference papers hal-01189844v1

In vitro exopure to environmental doses of BPA, MEHP and PCBs results in few transcriptions alterations in the fetal sheep ovary

Corinne Cotinot , Béatrice Mandon-Pepin , Benoît Loup , Maria R Amezaga , Richard G Lea et al.
SSR 46. Annual Meeting, Reproductive Health : Nano to Global Program, Jul 2013, Montréal, Canada
Conference papers hal-01189826v1

Topaz1 is essential for spermatogenesis and male fertility

Alix Luangpraseuth , Adrienne Baillet , Elodie Poumerol , Corinne Cotinot , Béatrice Mandon-Pepin et al.
17. Eurpean Workshop on Molecular and Cellular Endocrinology on the Testis, European Society for Sexual Medicine (ESSM). ITA.; Institut Curie. FRA., Apr 2012, Stockholm, Sweden. 1 p
Conference papers hal-01019621v1

Long term effects of environmental chemical exposure during development on the adult ovine reproductive neuroendocrine axis

M. Bellingham , P.A. Fowler , S.M. Rhind , Béatrice Mandon-Pepin , Corinne Cotinot et al.
British Society of Neuroendocrinology Annual Meeting, British Society for Neuroendocrinology (BSN). GBR., Jul 2011, Cambridge, United Kingdom. pp.1
Conference papers hal-01191266v1

Transcriptome profiling of sheep granulosa cells and oocytes during early follicular development obtained by Laser Capture Microdissection

Agnès Bonnet , Claudia Bevilacqua , Francis Benne , Loys Bodin , Corinne Cotinot et al.
1. Meeting of the Ovarian Club "The Oocyte : from Basic Research to Clinical Practice", Nov 2011, Barcelonne, Spain
Conference papers hal-01193855v1

Exposure of fetal germ cells (F2) to a complex mixture of environmentally-relevant chemicals via grand-maternal (F0) ingestion subtly affects the fetal ovarian proteome

Maria R M. R. Amezaga , Ja J. Skiba , M M. Fraser , Benoît B. Loup , Béatrice Mandon-Pepin et al.
6. Workshop on Endocrine Disrupters, Apr 2011, Copenhague, Denmark
Conference papers hal-01004518v1

Maternal exposure to a complex mixture of environmentally-relevant chemicals during critical developmental windows differentially affects fetal ovarian follicles and ovarian transcriptome

Benoît B. Loup , Béatrice Mandon-Pepin , Maria R M. R. Amezaga , Elodie Poumerol , Carol E C. E. Kyle et al.
6. Workshop on Endocrine Disrupters, Apr 2011, Copenhague, Denmark
Conference papers hal-01004519v1

Development of the fetal ovine HPG axis is perturbed by environmental concentrations of endocrine disrupting chemicals

Richard G R. G. Lea , Benoît B. Loup , Béatrice Mandon-Pepin , Maria R M. R. Amezzaga , Rebecca R. Mckinlay et al.
World Congress on Reproductive Biology, Oct 2011, Cairns, Australia
Conference papers hal-01004517v1

Tissue accumulation of selected endocrine disrupting compounds in fetuses following exposure to sewage sludge-treated pastures at different stages of gestation

Stewart M. S. M. Rhind , Carol. E. C. E. Kyle , Maria R. M. R. Ameezaga , Béatrice Mandon-Pepin , Benoît B. Loup et al.
6. Copenhagen Workshop on Endocrine Disrupters, Apr 2011, Copenhague, Denmark. 1 p
Conference papers hal-01001629v1
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La différenciation ovarienne précoce et son contrôle génétique

Adrienne Baillet , Béatrice Mandon-Pepin , Reiner Veitia , Corinne Cotinot
Différenciation et régulation des fonctions ovariennes : nouveaux concepts, Jun 2011, Paris, France. pp.201-221, ⟨10.1051/jbio/2011021⟩
Conference papers hal-01019059v1

La mise en place de l’ovaire chez les mammifères

Adrienne Baillet , Corinne Cotinot , Béatrice Mandon-Pepin
41. Journée Thématique de la Société Française pour l'étude de la fertilité (SFEF), Mar 2010, Paris, France
Conference papers hal-02752653v1

Effect of "real-life" environmental pollutant exposures on ovarian development and function in sheep

Béatrice Mandon-Pepin , Benoît Loup , Elodie Demondion , P. A. Fowler , M. R. Amezaga et al.
43. Annual Meeting of the Society for the Study of Reproduction, Jul 2010, Milwaukee, Wisconsin, United States
Conference papers hal-02754752v1

Ovine fetal testis development is perturbed by in-utero exposure to a cocktail of chemicals contained in sewage sludge

R. G. Lea , S.M. Rhind , B. Egbowon , M. R Amezaga , Corinne Cotinot et al.
Conference 2010 of the Society for Reproduction and Fertility, Jul 2010, Sutton Bonington, United Kingdom
Conference papers hal-02754444v1

Effect of in-utero and post-natal exposure to a complex cocktail of environmental chemicals on the ovarian proteome

M. R Amezaga , Corinne Cotinot , Béatrice Mandon-Pepin , Benoît Loup , Michelle Bellingham et al.
Gordon Research Conferences. Environmental Endocrine Disruptors, May 2010, Les Diablerets, Switzerland. 1 p
Conference papers hal-02814521v1

Mise en place de l’ovaire chez les mammifères : une fille se crée dans le ventre de sa mère

Adrienne Baillet , Corinne Cotinot , Béatrice Mandon-Pepin
15. Journées Nationales de la Fédération Française d'Etude de la Reproduction (FFER), Oct 2010, Paris, France. 1 p
Conference papers hal-02815860v1

Tissue accumulation of selected endocrine disrupting compounds in fetuses following exposure to sewage sludge-treated pastures at different stages of gestation

S.M. Rhind , C. E. Kyle , M. R Amezaga , Béatrice Mandon-Pepin , Benoît Loup et al.
Gordon Research Conferences. Environmental Endocrine Disruptors, May 2010, Les Diablerets, Switzerland. 1 p
Conference papers hal-02824117v1

Exposure to a cocktail of environmental chemicals at critical windows of fetal development: does timing matter to the fetus?

M. Amezaga , A. Stefansdottir , Marie Fraser , Corinne Cotinot , Béatrice Mandon-Pepin et al.
Conference 2010 of the Society for Reproduction and Fertility, Jul 2010, Sutton Bonington, United Kingdom
Conference papers hal-02754433v1

Effects of pollutants on the reproduction and welfare of ruminants

S.M. Rhind , M. Bellingham , R.M. Sharpe , Corinne Cotinot , N.P. Evans et al.
11 International Symposium on Ruminant Physiology, Sep 2009, Clermont-Ferrand, France
Conference papers hal-02754430v1

REFOLLIS , Restitution des résultats scientifiques dans les projets financés par l'ANR

Agnès Bonnet , Francis Benne , Loys L. Bodin , Julien J. Sarry , Laurence Liaubet et al.
VIIe Séminaire Agenae / Genanimal Tours, 21-23 octobre 2009 (oral, Oct 2009, Tours, France
Conference papers hal-02817818v1

Exposure to a cocktail of environmental chemicals alters the fetal uterus

Maria R. Amezaga , Julie Wilson , Michelle Bellingham , Neil P. Evans , Béatrice Mandon-Pepin et al.
Fertility 2009. The 6th biennial conference of the UK Fertility Societies: the Association of Clinical Embryologists (ACE), the British Fertility Society (BFS) and the Society for Reproduction and Fertility (SRF), Jan 2009, Edinburgh, United Kingdom
Conference papers hal-02755851v1
Image document

Goat as a Model for Studying R-Spondin Involvement in Ovarian Differentiation in Mammals

Aurélie Auguste , Fatemeh Montazer-Torbati , Ayhan Kocer , Maëlle Pannetier , Lauriane Renault et al.
20. International Congress of Zoology, Aug 2009, Paris, France
Conference papers hal-02751764v1

Sudden changes in exposure to environmental chemicals perturbs ovarian development.

Maria R. Amezaga , Christopher Jb Speers , Michelle Bellingham , Neil P. Evans , Béatrice Mandon-Pepin et al.
SRF Conference 2009 (Society for Reproduction and Fertility), Jul 2009, Oxford, United Kingdom
Conference papers hal-02754453v1

Long term effects of environmental EDC exposure on ovine pituitary KiSS-1 expression.

Michelle Bellingham , Paul A. Fowler , Richard M. Sharpe , Maria R. Amezaga , Béatrice Mandon-Pepin et al.
BSN MEETING 2009, Jun 2009, Edinburgh, United Kingdom. n.p
Conference papers hal-02816521v1

Tissue accumulation of endocrine disrupting compounds (EDC) in adult and fetal sheep following exposure to sewage sludge-treated pastures.

Stewart M. Rhind , C.E. Kyle , C. Mackie , L. Macdonald , E.I. Duff et al.
11. International Symposium on Ruminant Physiology (ISRP), Sep 2009, Clermont-Ferrand, France. n.p
Conference papers hal-02820070v1

Regulation of early folliculogenesis

Agnès Bonnet , Francis Benne , Claudia Bevilacqua , Loys L. Bodin , Corinne Cotinot et al.
Conférence Jacques Monod : L’ARN au centre de la régulation des gènes, Apr 2009, Roscoff, France. n.p
Conference papers hal-02815521v1

Impact des polluants environnementaux sur le développement de l'ovaire chez le mouton

Béatrice Mandon-Pepin , Benoît Loup , Elodie Poumerol , Corinne Cotinot
3. Journées d’Animation Scientifique du Département de Physiologie Animale et Systèmes d’Elevage, Oct 2009, Tours, France
Conference papers hal-02753493v1

Identification of transcripts involved in meiosis and follicle formation during ovine ovary development

Béatrice Mandon-Pepin , Adrienne Baillet , Cédric Cabau , Elodie Poumerol , Eric Pailhoux et al.
6. Workshop on Mammalian Folliculogenesis and oogenesis : from basic science to the clinic, Oct 2009, Potsdam, Germany. p:18
Conference papers hal-02819495v1

Goat as model for studying ovarian differentiation in mammals

Aurélie Auguste , Fatemeh Montazer-Torbati , Ayhan Kocer , Maëlle Pannetier , Lauriane Renault et al.
16. International Congress on Animal Reproduction, Jul 2008, Budapest, Hungary
Conference papers hal-02753828v1

Development of a goat-specific anti-SRY antibody: Preliminary rsults ongoat SRY protein expression

Fatemeh Montazer-Torbati , Aurélie Auguste , Maëlle Pannetier , Ayhan Kocer , Lauriane Renault et al.
20. International Congress of Zoology, Aug 2008, Paris, France. ⟨10.1159/000195677⟩
Conference papers hal-02752007v1

Identification of genes expressed during sheep ovarian development by SSH

Béatrice Mandon-Pepin , Adrienne Baillet , Elodie Poumerol , Corinne Cotinot
4. International Symposium on the Biology of Vertebrate Sex Determination, Apr 2006, Hawaii, United States. 1 p
Conference papers hal-02812656v1

Le modèle murin est-il représentatif des mammifères?

Corinne Cotinot , Eric Pailhoux , Béatrice Mandon-Pepin , Maëlle Pannetier , Lauriane Renault et al.
5. Atelier Déterminisme et Différenciation du Sexe, Sep 2004, Nancy, France
Conference papers hal-02764365v1

Expression profiles and localization of genes involved in ovarian differentiation in sheep

Béatrice Mandon-Pepin , A. Oustry-Vaiman , François Piumi , E.P. Cribiu , Corinne Cotinot et al.
International Workshop on Major Genes and QTL in Sheep and Goat, Dec 2003, Toulouse, France. pp.Communication n° 2-09
Conference papers hal-02762490v1

Mécanismes, régulations et manipulations de l'atrésie folliculaire

Danielle Monniaux , Camille Huet , C. Pisselet , Béatrice Mandon-Pepin , Philippe Monget et al.
3. Journées de la Fédération Française d'Etude de la Reproduction, Sep 1998, Paris, France
Conference papers hal-02838205v1

Système IGF et développement folliculaire

Philippe Monget , N. Besnard , S. Mazerbourg , Béatrice Mandon-Pepin , C. Pisselet et al.
1. Journées d'Information Scientifique du Département de Physiologie animale, 1997, Tours, France
Conference papers hal-02770025v1
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Introduction d'une étiquette FLAG à la protéine TOPAZ1 par recombinaison homologue directement dans le zygote

Elodie Poumerol , Manon Chadourne , Bruno Passet , Johann Castille , Geneviève Jolivet et al.
Journée d'animation Scientifique PHASE, May 2022, Futuroscope, Poitiers, France
Conference poster hal-03777393v1
Image document

CAROT -Cell Atlas of Rabbit Ovarian Transcripts

Namya Mellouk , Béatrice Mandon-Pepin , Aurélie Dewaele , Luc Jouneau , Emilie Dujardin et al.
Journée d'animation Scientifique PHASE, May 2022, Futuroscope, Poitiers, France
Conference poster hal-03777412v1

Single-cell RNA Transcriptome Atlas of the Developing Fetal Rabbit Ovary

Namya Mellouk , Béatrice Mandon-Pepin , Aurélie Dewaele , Luc Jouneau , Emilie Dujardin et al.
First Virtual International Symposium on Vertebrate Sex Determination, Oct 2021, Kona, Hawaii, United States
Conference poster hal-03367293v1

CHARACTERIZATION OF ESTROGEN PRODUCTION AND FUNCTION IN ADULT RABBIT TESTES

Aurélie Dewaele , Emilie Dujardin , Hélène Jammes , Franck Giton , Béatrice Mandon-Pepin et al.
54th SSR Annual Meeting, Dec 2021, Saint-Louis, United States
Conference poster hal-03599844v1

Single-cell RNA Transcriptome Atlas of the Developing Fetal Rabbit Ovary

Namya Mellouk , Béatrice Mandon-Pepin , Aurélie Dewaele , Luc Jouneau , Emilie Dujardin et al.
54th SSR Annual Meeting, Dec 2021, Saint-Louis, United States
Conference poster hal-03601202v1

Différenciation et reprogrammation épigénétique de la lignée germinale – Analyses transcriptomiques à l’échelle de la cellule.

Geneviève Jolivet , Hérault Eloïse , Aurélie Allais-Bonnet , Marjolaine André , Béatrice Mandon-Pepin et al.
Séminaire Défis Scientifiques du Département Physiologie Animale et Systèmes d'Elevage, 2019, Rennes, France
Conference poster hal-02949117v1

Long non-coding RNA function during meiotic divisions of spermatogenesis in mammals : link with Topaz1

Manon Chadourne , Elodie Poumerol , Bruno Passet , Luc Jouneau , Eric Pailhoux et al.
3. Journées du GdR 3606 Repro, Apr 2019, Toulouse, France. , 2019
Conference poster hal-02790680v1

Long non-coding RNA function during meiotic divisions of spermatogenesis in mammals

Manon Chadourne , Elodie Poumerol , Béatrice Mandon-Pepin
Atelier 251- Non coding RNA: from detection to function, Sep 2018, Bordeaux, France. , 2018
Conference poster hal-02787900v1
Image document

DNA methylation dynamics during spermatogenesis in ruminants

Aurélie Allais-Bonnet , Sébastien Messiaen , Marjolaine André , Béatrice Mandon-Pepin , Gabriel Livera et al.
Mammalian Reproductive Gordon Research, Jul 2018, Lucca, Italy. , 2018
Conference poster hal-02790316v1

Topaz1: an actor of the spermatogenesis

Béatrice Mandon-Pepin , Alix Luangpraseuth , Manon Chadourne , Elodie Lesueur , Luc Jouneau et al.
2. Journées Scientifiques du GdR Repro, Apr 2017, Tours, France. , 76 p., 2017, 2èmes Journées scientifiques GDR REPRO 2017
Conference poster hal-01603127v1

Effects of low dose of bisphenol A on sheep fetal testis and ovary

Barbara B. Panneau , Béatrice Mandon-Pepin , Maëlle Pannetier , Luc Jouneau , Corinne Cotinot et al.
18. International Congress on Animal Reproduction (ICAR), Jun 2016, Tours, France. , 676 p., 2016, 18th International Congress on Animal Reproduction (ICAR)
Conference poster hal-02742377v1

Lifelong exposure to sewage sludge chemicals causes proteome-wide and sex-specific disturbances in the liver

Panagiotis Filis , Emily Eaton-Turner , Michelle Bellingham , Maria Amezaga , Béatrice Mandon-Pepin et al.
Society for Endocrinology BES 2015, Nov 2015, Edimbourgh, United Kingdom. BioScientifica, Endocrine Abstracts, 38, 2015, Endocrine Abstracts 2015. ⟨10.1530/endoabs.38.P250⟩
Conference poster hal-02743480v1

Topaz1: a new actor of the spermatogenesis

Alix Luangpraseuth Prosper , Fanny Husson , Elodie Lesueur , Corinne Cotinot , Béatrice Mandon-Pepin et al.
1. Journées du GdR 3606 Repro, Apr 2015, Rennes, France. , 105 p., 2015, 1ères Journées Scientifiques du GdR Repro
Conference poster hal-02742537v1

The Topaz1 gene is necessary for spermatogenesis

Alix A. Luangpraseuth , Elodie Poumerol , Adrienne Baillet , Corinne Cotinot , Béatrice Mandon-Pepin et al.
18. European Testis Workshop, May 2014, Elsinore, Denmark. , 1 p., 2014
Conference poster hal-02798148v1

Caractérisation du modèle murin invalidé pour le gène : TOPAZ1 (Testis and ovaryspecific PAZ domain gene)

Alix A. Luangpraseuth , Elodie Lesueur , Corinne Cotinot , Béatrice Mandon-Pepin
5. Journées d'Animation Scientifique du département Phase (JAS Phase 2013), Oct 2013, Paris, France. 2013
Conference poster hal-02811374v1

Environmental chemical exposure during development affects adult kisspeptin/ERα immunoexpression in the POA but not the ARC

M. Bellingham , V. Capinalp , P.A. Fowler , R.M. Sharpe , M.R. Amezaga et al.
Annual Meeting of the British Society for Neuroendocrinology, Jul 2012, Aberdeen, United Kingdom. , 1 p., 2012
Conference poster hal-02807808v1

Caractérisation d'un nouveau gène, Topaz1, spécifique des cellules germinales et conservé au cours de l'évolution des Vertébrés

Béatrice Mandon-Pepin , Adrienne Baillet , Alix A. Luangpraseuth , Elodie Poumerol , Corinne Cotinot et al.
Journée d'animation Scientifique, Jan 2012, Rennes, France. , 2012
Conference poster hal-02810502v1

Maternal exposure to DEHP and PCB congeners (101+118): Differential effects on the male and female pituitary-gonadal axis

R.G. Lea , Benoît Loup , Béatrice Mandon-Pepin , M.R. Amezaga , Rebecca Mckinlay et al.
6. Copenhagen Workshop on Endocrine Disrupters, Apr 2011, Copenhague, Denmark. , 1 p., 2011
Conference poster hal-02808520v1

Etude d'un nouveau gène exprimé dans les gonades de mammifères: TOPAZ1

Béatrice Mandon-Pepin , Adrienne Baillet , Corinne Cotinot
Journées d’Animation des Crédits Incitatifs du Département de Physiologie Animale et Systèmes d’Elevage (JACI Phase), Oct 2010, Tours, France. 2010
Conference poster hal-02824646v1

Tissue accumulation of selected endocrine disrupting compounds in fetuses following exposure to sewage sludge-treated pastures at different stages of gestation

Stewart M. Rhind , C.E. Kyle , Maria R. Amezaga , Béatrice Mandon-Pepin , Benoît Loup et al.
Gordon Research Conferences. Environmental Endocrine Disruptors, May 2010, Les Diablerets, Switzerland. , 1 p., 2010
Conference poster hal-02820175v1

Effect of in-utero and post-natal exposures to a complex cocktail of environmental chemicals (ECs) on the ewe ovarian transcriptome

Béatrice Mandon-Pepin , Benoît Loup , P.A. Fowler , Maria R. Amezzaga , Richard Sharpe et al.
Gordon Research Conferences. Environmental Endocrine Disruptors, May 2010, Les Diablerets, Switzerland. , 1 p., 2010
Conference poster hal-02820285v1

Consequences of in-utero exposure to environmental chemicals on ovary development in sheep

Béatrice Mandon-Pepin , Benoît Loup , Elodie Poumerol , Paul A. Fowler , Maria R. Amezaga et al.
5. Copenhagen Workshop on Endocrine Disrupters, May 2009, Copenhague, Denmark. n.p., 2009
Conference poster hal-02817440v1

Identification of genes expressed during sheep ovarian development

Adrienne Baillet , Béatrice Mandon-Pepin , Cédric Cabau , Elodie Poumerol , Eric Pailhoux et al.
16. International Congress on Animal Reproduction (ICAR), Jul 2008, Budapest, Hungary. Reproduction in Domestic Animals, 43 (Suppl. 3), pp.145-145, 2008, ⟨10.1111/j.1439-0531.2008.01234.x⟩
Conference poster hal-02751476v1

Functional analysis of Dmc1 polymorphism found in human infertility

Juri Hikiba , Kouji Hirota , Shukuko Ikawa , Takashi Kinebuchi , Isao Sakane et al.
30. Annual Meeting of the Japanese Molecular Biology Society, Dec 2007, Yokohama, Japan. 1 p., 2007
Conference poster hal-02816417v1

Human genetic of premature ovarian failure: a mendelian and candidate genes approach

Sandrine Caburet , Frank Batista , Paul Laissue , A. Veitia Reiner , Marc Fellous et al.
"The First Seven days: from gametes to blastocysts and stem cell". Serono Symposium, Apr 2006, Tampa, United States. 1 p., 2006
Conference poster hal-02816892v1

Système BMP, nouvel acteur de la différenciation gonadique?

Béatrice Mandon-Pepin , A. Pierre , Stéphane Fabre , Corinne Cotinot
5. Atelier Déterminisme et Différenciation du Sexe, Sep 2004, Nancy, France. 2004, 5ème Atelier Déterminisme et Différenciation du Sexe
Conference poster hal-02764089v1