Access content directly

BENJAMIN CHAGOT

28
Documents

Publications

Image document

Towards improved understanding of intersubunit interactions in modular polyketide biosynthesis: Docking in the enacyloxin IIa polyketide synthase

Fanny Risser , Sabrina Collin , Raphael dos Santos-Morais , Arnaud Gruez , Benjamin Chagot et al.
Journal of Structural Biology, 2020, 212 (1), pp.107581. ⟨10.1016/j.jsb.2020.107581⟩
Journal articles hal-02926190v1
Image document

Insights into a dual function amide oxidase/macrocyclase from lankacidin biosynthesis

Jonathan Dorival , Fanny Risser , Christophe Jacob , Sabrina Collin , Gerald Dräger et al.
Nature Communications, 2018, 9 (1), pp.3998. ⟨10.1038/s41467-018-06323-w⟩
Journal articles hal-01980537v1
Image document

Characterization of Intersubunit Communication in the Virginiamycin trans-Acyl Transferase Polyketide Synthase

Jonathan Dorival , Thibault Annaval , Fanny Risser , Sabrina Collin , Pierre Roblin et al.
Journal of the American Chemical Society, 2016, 138 (12), pp.4155-4167. ⟨10.1021/jacs.5b13372⟩
Journal articles hal-01452317v1

Bacteriophage SPP1 tail tube protein self-assembles into β-structure-rich tubes.

Chantal Langlois , Stéphanie Ramboarina , Abhishek Cukkemane , Isabelle Auzat , Benjamin Chagot et al.
Journal of Biological Chemistry, 2015, 290 (6), pp.3836-49. ⟨10.1074/jbc.M114.613166⟩
Journal articles hal-01449521v1

Insights into the function of trans-acyl transferase polyketide synthases from the SAXS structure of a complete module

Jack Davison , Jonathan Dorival , Hery Rabeharindranto , Hortense Mazon , Benjamin Chagot et al.
Chemical Science, 2014, 5 (8), pp.3081-3095. ⟨10.1039/c3sc53511h⟩
Journal articles hal-01453210v1

Function of polyketide synthases from the SAXS structure of a complete module

Jack Davison , Jonathan Dorival , Hery Rabeharindranto , Hortense Mazon , Benjamin Chagot et al.
Acta Crystallographica Section A : Foundations and Advances [2014-..], 2014, 70 (a1), pp.C407 - C407. ⟨10.1107/S2053273314095928⟩
Journal articles hal-01653555v1

Inhibition of Histone Deacetylase 3 Causes Replication Stress in Cutaneous T Cell Lymphoma

Christina Wells , Srividya Bhaskara , Kristy R. Stengel , Yue Zhao , Bianca Sirbu et al.
PLoS ONE, 2013, 8 (7), ⟨10.1371/journal.pone.0068915⟩
Journal articles hal-01637728v1
Image document

NMR studies of the interaction of calmodulin with IQ motif peptides.

Steven Damo , Michael D Feldkamp , Benjamin Chagot , Walter J Chazin
Methods in Molecular Biology, 2013, Calcium-Binding Proteins and RAGE 963, pp.173-86. ⟨10.1007/978-1-62703-230-8_11⟩
Journal articles hal-01637792v1

Solution structure of gp17 from the Siphoviridae bacteriophage SPP1: Insights into its role in virion assembly

Benjamin Chagot , Isabelle Auzat , Matthieu Gallopin , Isabelle Petitpas , Bernard Gilquin et al.
Proteins - Structure, Function and Bioinformatics, 2012, 80 (1), pp.319 - 326. ⟨10.1002/prot.23191⟩
Journal articles hal-01637793v1
Image document

Solution NMR Structure of Apo-Calmodulin in Complex with the IQ Motif of Human Cardiac Sodium Channel NaV1.5

Benjamin Chagot , Walter J. Chazin
Journal of Molecular Biology, 2011, 406 (1), pp.106 - 119. ⟨10.1016/j.jmb.2010.11.046⟩
Journal articles hal-01636790v1

Solution NMR Structure of the C-terminal DNA Binding Domain of Mcm10 Reveals a Conserved MCM Motif

Patrick Robertson , Benjamin Chagot , Walter J. Chazin , Brandt F. Eichman
Journal of Biological Chemistry, 2010, 285 (30), pp.22942 - 22949. ⟨10.1074/jbc.M110.131276⟩
Journal articles hal-01637795v1

Solution NMR Structure of the C-terminal EF-hand Domain of Human Cardiac Sodium Channel Na V 1.5

Benjamin Chagot , Franck Potet , Jeffrey R. Balser , Walter J. Chazin
Journal of Biological Chemistry, 2009, 284 (10), pp.6436 - 6445. ⟨10.1074/jbc.M807747200⟩
Journal articles hal-01636789v1

Structure-Function Analysis of Inositol Hexakisphosphate-induced Autoprocessing in Clostridium difficile Toxin A

Rory Pruitt , Benjamin Chagot , Michael Cover , Walter J. Chazin , Ben Spiller et al.
Journal of Biological Chemistry, 2009, 284 (33), pp.21934 - 21940. ⟨10.1074/jbc.M109.018929⟩
Journal articles hal-01637796v1

Functional Interactions between Distinct Sodium Channel Cytoplasmic Domains through the Action of Calmodulin

Franck Potet , Benjamin Chagot , Mircea Anghelescu , Prakash C. Viswanathan , Svetlana Z. Stepanovic et al.
Journal of Biological Chemistry, 2009, 284 (13), pp.8846 - 8854. ⟨10.1074/jbc.M806871200⟩
Journal articles hal-01637798v1
Image document

Calcium-Dependent Regulation of Ion Channels.

Vikas N Shah , Benjamin Chagot , Walter J Chazin
Calcium binding proteins, 2006, pp.203-212
Journal articles hal-01652606v1
Image document

Solution structure of PcFK1, a spider peptide active against Plasmodium falciparum

Cyril Pimentel , Soo-Jin Choi , Benjamin Chagot , Catherine Guette , Jean-Michel Camadro et al.
Protein science : a publication of the Protein Society., 2006, 15(3), pp.628-34. ⟨10.1110/ps.051860606⟩
Journal articles hal-00018558v1

An unusual fold for potassium channel blockers: NMR structure of three toxins from the scorpion Opisthacanthus madagascariensis

Benjamin Chagot , Cyril Pimentel , Li Dai , Joost Pil , Jan Tytgat et al.
Biochemical Journal, 2005, 388 (1), pp.263-271. ⟨10.1042/BJ20041705⟩
Journal articles hal-01636774v1

Solution structure of APETx2, a specific peptide inhibitor of ASIC3 proton-gated channels

Benjamin Chagot , Pierre Escoubas , Sylvie Diochot , Cedric Bernard , Michel Lazdunski et al.
Protein Science, 2005, 14 (8), pp.2003-2010. ⟨10.1110/ps.051378905⟩
Journal articles hal-01636767v1

Solution structure of APETx1 from the sea anemone Anthopleura elegantissima: A new fold for an HERG toxin

Benjamin Chagot , Sylvie Diochot , Cyril Pimentel , Michel Lazdunski , Hervé Darbon et al.
Proteins - Structure, Function and Bioinformatics, 2005, 59 (2), pp.380 - 386. ⟨10.1002/prot.20425⟩
Journal articles hal-01636397v1

Solution structure of two insect-specific spider toxins and their pharmacological interaction with the insect voltage-gated Na+ channel

G. Ferrat , F. Bosmans , J. Tytgat , C. Pimentel , Benjamin Chagot et al.
Proteins - Structure, Function and Bioinformatics, 2005, 59 (2), pp.368 - 379. ⟨10.1002/prot.20424⟩
Journal articles hal-01636782v1

Increasing the molecular contacts between maurotoxin and Kv1.2 channel augments ligand affinity.

Sarrah M'Barek , Benjamin Chagot , Nicolas Andreotti , Violeta Visan , Pascal Mansuelle et al.
Proteins - Structure, Function and Bioinformatics, 2005, 60 (3), pp.401-11. ⟨10.1002/prot.20509⟩
Journal articles inserm-00381749v1

Solution structure of Phrixotoxin 1, a specific peptide inhibitor of Kv4 potassium channels from the venom of the theraphosid spider Phrixotrichus auratus

Benjamin Chagot , Pierre Escoubas , Elba Villegas , Cedric Bernard , Gilles Ferrat et al.
Protein Science, 2004, 13 (5), pp.1197-1208. ⟨10.1110/ps.03584304⟩
Journal articles hal-01636765v1

Structure-function relationships in modular PKSs and their application to genetic engineering

Kira J Weissman , Fanny Risser , Jean-Malo Massicard , Sabrina Collin , Raphael dos Santos Morais et al.
MegaSyn Symposium, 2020, Bad Nauheim, Germany
Conference papers hal-02956682v1

Are the ubiquitous mitochondrial glutaredoxin-like proteins of 12 kDa (MGP12) true glutaredoxins?

Tiphaine Dhalleine , Mathieu Schwartz , Marc Quinternet , Benjamin Chagot , Benjamin Petre et al.
Thiol-based switches and redox regulation – from microbes to men, Sep 2019, San Feliu de Guixols, Spain
Conference papers hal-03197996v1

Decrypting structure-function relationships in modular PKSs

Kira J Weissman , Jack Davison , Jonathan Dorival , Thibault Annaval , Fanny Risser et al.
From mutases to megasynthases: celebrating the career of Professor Peter Leadlay. Retirement symposium for Prof. Peter Leadlay., 2018, Cambridge, United Kingdom
Conference papers hal-03016899v1

The structural biology of modular polyketide synthases: insights and implications for synthetic biology

Kira J Weissman , Jack Davison , Jonathan Dorival , Thibault Annaval , Fanny Risser et al.
3rd European Conference on Natural Products, 2018, Frankfurt, Germany
Conference papers hal-02956684v1

The structural biology of modular polyketide synthases: insights and implications for synthetic biology

Kira J. Weissman , Jonathan Dorival , Thibault Annaval , Fanny Risser , Sabrina Collin et al.
European Workshop on Natural Product Biosynthesis, Jun 2017, Gif-sur-Yvete, France
Conference papers hal-01736000v1

Deciphering the structures of trans-AT polyketide synthases

Kira J. Weissman , Jack Davison , Jonathan Dorival , Thibault Annaval , Fanny Risser et al.
BMWZ Symposium, Sep 2016, Hannover, Germany
Conference papers hal-01735998v1