Benoit Joseph

29
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Publications

Publications

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Identifying Potent Nonsense-Mediated mRNA Decay Inhibitors with a Novel Screening System

Julie Carrard , Fiona Ratajczak , Joséphine Elsens , Catherine Leroy , Rebekah Kong et al.
Biomedicines, 2023, 11 (10), ⟨10.3390/biomedicines11102801⟩
Article dans une revue hal-04250857 v1

Exatecan Antibody Drug Conjugates Based on a Hydrophilic Polysarcosine Drug-Linker Platform

Louise Conilh , Guy Fournet , Eric Fourmaux , Angélique Murcia , Eva-Laure Matera et al.
Pharmaceuticals, 2021, 14 (3), pp.247. ⟨10.3390/ph14030247⟩
Article dans une revue hal-03215941 v1

Monomethyl Auristatin E Grafted-Liposomes to Target Prostate Tumor Cell Lines

Ariana Abawi , Xiaoyi Wang , Julien Bompard , Anna Bérot , Valentina Andretto et al.
International Journal of Molecular Sciences, 2021, 22 (8), pp.4103. ⟨10.3390/ijms22084103⟩
Article dans une revue (article de synthèse) hal-04851780 v1

Monodisperse polysarcosine-based highly-loaded antibody-drug conjugates

Warren Viricel , Guy Fournet , Sabine Beaumel , Emeline Perrial , Sébastien Papot et al.
Chemical Science, 2019, 10 (14), pp.4048-4053. ⟨10.1039/C9SC00285E⟩
Article dans une revue hal-02134857 v1
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Room-Temperature and Transition-Metal-Free Intramolecular α-Arylation of Ketones: A Mild Access to Tetracyclic Indoles and 7-Azaindoles

Chérif Adouama , María Budén , Walter Guerra , Marcelo Puiatti , Benoît Joseph et al.
Organic Letters, 2018, 21 (1), pp.320-324. ⟨10.1021/acs.orglett.8b03831⟩
Article dans une revue hal-03093867 v1
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Targeting RNA structure in SMN2 reverses spinal muscular atrophy molecular phenotypes

Amparo Garcia-Lopez , Francesca Tessaro , Hendrik R A Jonker , Anna Wacker , Christian Richter et al.
Nature Communications, 2018, 9 (1), ⟨10.1038/s41467-018-04110-1⟩
Article dans une revue hal-02115789 v1

Correction: Characterization of Transglutaminase 2 activity inhibitors in monocytes in vitro and their effect in a mouse model for multiple sclerosis

Navina Chrobok , John Bol , Cornelis Jongenelen , John Brevé , Said El Alaoui et al.
PLoS ONE, 2018, 13 (12), pp.e0209522. ⟨10.1371/journal.pone.0209522⟩
Article dans une revue hal-02134577 v1

Room-Temperature and Transition-Metal-Free Intramolecular α-Arylation of Ketones: A Mild Access to Tetracyclic Indoles and 7-Azaindoles

Chérif Adouama , María Budén , Walter Guerra , Marcelo Puiatti , Benoît Joseph et al.
Organic Letters, 2018, 21 (1), pp.320-324. ⟨10.1021/acs.orglett.8b03831⟩
Article dans une revue hal-02134648 v1

Synthesis and biological evaluation of tetrahydro[1,4]diazepino[1,2-a]indol-1-ones as cyclin-dependent kinase inhibitors

Putey Aurelien , Fournet Guy , Olivier Lozach , Lionel Perrin , Meijer Laurent et al.
European Journal of Medicinal Chemistry, 2014, 83, pp.617-629
Article dans une revue hal-01147615 v1

Impact of meriolins, a new class of cyclin-dependent kinase inhibitors, on malignant glioma proliferation and neo-angiogenesis.

Marie Jarry , Céline Lecointre , Céline Malleval , Laurence Desrues , Marie-Thérèse Schouft et al.
Neuro-Oncology, 2014, 16 (11), pp.1484-98
Article dans une revue hal-01109355 v1

New 1-arylindoles based serotonin 5-HT7 entagonists. Synthesis and binding evaluation studies

Charlène Sagnes , Guy Fournet , Grzegorz Satala , Andrzej J. Bojarski , Benoît Joseph
European Journal of Medicinal Chemistry, 2014, 75, pp.159-168
Article dans une revue hal-01147626 v1

Recent advances in the synthesis and properties of 4-, 5-, 6- or 7-azaindoles

Jean-Yves Mérour , Sylvain Routier , Franck Suzenet , Benoît Joseph
Tetrahedron, 2013, 69 (24), pp.4767-4834. ⟨10.1016/j.tet.2013.03.081⟩
Article dans une revue istex hal-04451515 v1

Inhibition of hepatitis C virus NS5B polymerase by S-trityl-L-cysteine derivatives.

Daniel B Nichols , Guy Fournet , K. R. Gurukumar , Amartya Basu , Jin-Ching Lee et al.
European Journal of Medicinal Chemistry, 2012, 49, pp.191-9. ⟨10.1016/j.ejmech.2012.01.010⟩
Article dans une revue hal-00691431 v1

Targeting low molecular weight cyclin E (LMW-E) in breast cancer.

Angela Nanos-Webb , Natalie A Jabbour , Asha S Multani , Hannah Wingate , Nassima Oumata et al.
Breast Cancer Research and Treatment, 2012, 132 (2), pp.575-88. ⟨10.1007/s10549-011-1638-4⟩
Article dans une revue hal-00691433 v1

Unexpected matrix interactions in liquid secondary ion mass spectrometry of two pyranosyl mercaptans

Christian Gardrat , Benoît Joseph , Christiane Vitry , Alain Castellan , Patrick Rollin
Rapid Communications in Mass Spectrometry, 2011, 25 (10), pp.1399-1406. ⟨10.1002/rcm.4998⟩
Article dans une revue istex hal-00677750 v1

Structure-activity relationship and multidrug resistance study of new S-trityl-L-cysteine derivatives as inhibitors of Eg5.

Hung Yi Kristal Kaan , Johanna Weiss , Dominik Menger , Venkatasubramanian Ulaganathan , Katarzyna Tkocz et al.
Journal of Medicinal Chemistry, 2011, 54 (6), pp.1576-86. ⟨10.1021/jm100991m⟩
Article dans une revue hal-00691439 v1

New insights into homopiperazine-based 5-HT1A/5-HT7R ligands: synthesis and biological evaluation.

Eduard Badarau , Aurélien Putey , Franck Suzenet , Benoit Joseph , Andrzej Bojarski et al.
Journal of Enzyme Inhibition and Medicinal Chemistry, 2010, 25 (3), pp.301-5. ⟨10.3109/14756360903179393⟩
Article dans une revue hal-00691441 v1

Synthesis of 2-, 3-, and 4-Substituted Pyrido[2,3-b]indoles by C-N, C-O, and C-C(sp) Bond Formation

Cédric Schneider , David Goyard , David Gueyrard , Benoît Joseph , Peter Goekjian
European Journal of Organic Chemistry, 2010, 2010 (34), pp.6665-6677. ⟨10.1002/ejoc.201000795⟩
Article dans une revue istex hal-02351724 v1

Chemoselective functionalization of α-carbolines at the C-2, C-3, C-4, and C-6 positions using Suzuki–Miyaura reactions

Cédric Schneider , David Gueyrard , Benoît Joseph , Peter Goekjian
Tetrahedron, 2009, 65 (27), pp.5427-5437. ⟨10.1016/j.tet.2009.04.032⟩
Article dans une revue hal-02351645 v1

Pyrazolo[1,5-a]-1,3,5-triazine as a purine bioisostere: access to potent cyclin-dependent kinase inhibitor (R)-roscovitine analogue.

Florence Popowycz , Guy Fournet , Cédric Schneider , Karima Bettayeb , Yoan Ferandin et al.
Journal of Medicinal Chemistry, 2009, 52 (3), pp.655-63. ⟨10.1021/jm801340z⟩
Article dans une revue hal-00416036 v1

Indolobenzazepin-7-ones and 6-, 8-, and 9-membered ring derivatives as tubulin polymerization inhibitors: synthesis and structure--activity relationship studies.

Aurélien Putey , Florence Popowycz , Quoc-Tuan Do , Philippe Bernard , Sandeep K Talapatra et al.
Journal of Medicinal Chemistry, 2009, 52 (19), pp.5916-25. ⟨10.1021/jm900476c⟩
Article dans une revue hal-00691446 v1

Synthesis and antiproliferative evaluation of pyrazolo[1,5-a]-1,3,5-triazine myoseverin derivatives.

Florence Popowycz , Cédric Schneider , Salvatore Debonis , Dimitrios Skoufias , Frank Kozielski et al.
Bioorganic and Medicinal Chemistry, 2009, 17 (9), pp.3471-8. ⟨10.1016/j.bmc.2009.03.007⟩
Article dans une revue istex hal-00691448 v1

Meriolins (3-(pyrimidin-4-yl)-7-azaindoles): synthesis, kinase inhibitory activity, cellular effects, and structure of a CDK2/cyclin A/meriolin complex.

Aude Echalier , Karima Bettayeb , Yoan Ferandin , Olivier Lozach , Monique Clément et al.
Journal of Medicinal Chemistry, 2008, 51 (4), pp.737-51. ⟨10.1021/jm700940h⟩
Article dans une revue istex hal-00319787 v1

Synthesis and reactivity of 7-azaindole (1H-pyrrolo[2,3-b]pyridine)

Florence Popowycz , Sylvain Routier , Benoît Joseph , Jean-Yves Mérour
Tetrahedron, 2007, 63 (5), pp.1031-1064. ⟨10.1016/j.tet.2006.09.067⟩
Article dans une revue istex hal-04451569 v1

Synthesis and antiproliferative activity of clausine E, mukonine, and koenoline bioisosteres

François Liger , Florence Popowycz , Thierry Besson , Laurent Picot , Carlos Galmarini et al.
Bioorganic and Medicinal Chemistry Letters, 2007, 15 (16), pp.5615-5619. ⟨10.1016/j.bmc.2007.05.033⟩
Article dans une revue istex hal-02357763 v1

Synthesis of 6-Substituted Pyrido[2,3- b ]indoles by Electrophilic Substitution

Cédric Schneider , David Gueyrard , Florence Popowycz , Benoît Joseph , Peter Goekjian
SYNLETT, 2007, 2007 (14), pp.2237-2241. ⟨10.1055/s-2007-985566⟩
Article dans une revue hal-02380611 v1

Chemoselective functionalization of α-carbolines at 2-, 3-, 4- and 6-positions by Suzuki-Miyaura reaction

Cédric Schneider , Florence Popowycz , Joseph Benoît , Peter G. Goekjian , Gueyrard David
Canadian Chemistry Conference and Exhibition (CSC, 92, 2009), May 2009, Hamilton, Canada
Communication dans un congrès hal-02381196 v1

Functionnalization of α-carbolines at the C-6 position

Cédric Schneider , Gueyrard David , Popowycz Florence , Joseph Benoît , Peter G. Goekjian
Symposium de chimie organique Centre-Auvergne-Limousin Poitou-Charente-SYCOCAL PC (52, 2007), May 2007, La Rochelle, France
Communication dans un congrès hal-02381215 v1