Bertrand Dubois

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The spatial organization of cDC1 with CD8+ T cells is critical for the response to immune checkpoint inhibitors in melanoma patients

Elisa Gobbini , Margaux Hubert , Anne-Claire Doffin , Anais Eberhardt , Léo Hermet et al.
Cancer Immunology Research, 2025, ⟨10.1158/2326-6066.CIR-24-0421⟩
Article dans une revue hal-04879746 v1

The CSF-1R inhibitor pexidartinib affects FLT3-dependent DC differentiation and may antagonize durvalumab effect in patients with advanced cancers

Aurélien Voissière , Carlos Gomez-Roca , Sylvie Chabaud , Céline Rodriguez , Axelle Nkodia et al.
Science Translational Medicine, 2024, 16 (731), ⟨10.1126/scitranslmed.add1834⟩
Article dans une revue hal-04645010 v1
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KIR2DL2/DL3+NKs and Helios+Tregs in peripheral blood predict nivolumab response in patients with metastatic renal cell cancer

Sara Santagata , Anna Maria Trotta , Crescenzo d'Alterio , Maria Napolitano , Giuseppina Rea et al.
Clinical Cancer Research, 2024, ⟨10.1158/1078-0432.CCR-24-0729⟩
Article dans une revue hal-04675471 v1
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Modulation of blood T cell polyfunctionality and HVEM/BTLA expression are critical determinants of clinical outcome in anti-PD1-treated metastatic melanoma patients

Stéphane Dalle , Estelle Verronese , Axelle N’kodia , Christine Bardin , Céline Rodriguez et al.
OncoImmunology, 2024, 13 (1), pp.2372118. ⟨10.1080/2162402X.2024.2372118⟩
Article dans une revue hal-04632685 v1
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Immunomic longitudinal profiling of the NeoPembrOv trial identifies drivers of immunoresistance in high-grade ovarian carcinoma

Olivia Le Saux , Maude Ardin , Justine Berthet , Sarah Barrin , Morgane Bourhis et al.
Nature Communications, 2024, 15 (1), pp.5932. ⟨10.1038/s41467-024-47000-5⟩
Article dans une revue hal-04655437 v1

The CSF-1R inhibitor pexidartinib affects FLT3-dependent DC differentiation and may antagonize durvalumab effect in patients with advanced cancers

Aurélien Voissière , Carlos Gomez-Roca , Sylvie Chabaud , Céline Rodriguez , Axelle Nkodia et al.
Science Translational Medicine, 2024, 16 (731), ⟨10.1126/scitranslmed.add1834⟩
Article dans une revue hal-04999897 v1

Different Genetic Signatures of Small‐Cell Lung Cancer Characterize <scp>Anti‐GABA<sub>B</sub>R</scp> and <scp>Anti‐Hu</scp> Paraneoplastic Neurological Syndromes

Alberto Vogrig , Antoine Pegat , Macarena Villagrán‐garcía , Valentin Wucher , Valéry Attignon et al.
Annals of Neurology, 2023, 94 (6), pp.1102 - 1115. ⟨10.1002/ana.26784⟩
Article dans une revue hal-04401076 v1
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Pembrolizumab in Lymphopenic Metastatic Breast Cancer Patients Treated with Metronomic Cyclophosphamide: A Clinical and Translational Prospective Study

Benoîte Mery , Christine Ménétrier-Caux , Laure Montané , Pierre-Etienne Heudel , Isabelle Ray-Coquard et al.
Breast Cancer, 2023, 15, pp.311 - 325. ⟨10.2147/bctt.s400055⟩
Article dans une revue hal-04210158 v1

Structures lymphoïdes tertiaires : de la biogenèse à l’impact thérapeutique en cancérologie

Stanislas Quesada , Coriolan Lebreton , Christophe Caux , Antoine Italiano , Bertrand Dubois
Bulletin du Cancer, 2023, 110 (6), pp.657-664. ⟨10.1016/j.bulcan.2023.04.010⟩
Article dans une revue hal-04879774 v1
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Immune and Genetic Signatures of Breast Carcinomas Triggering Anti-Yo–Associated Paraneoplastic Cerebellar Degeneration

Elise Peter , Isabelle Treilleux , Valentin Wucher , Emma Jougla , Alberto Vogrig et al.
Neurology Neuroimmunology & Neuroinflammation, 2022, 9 (5), pp.e200015. ⟨10.1212/nxi.0000000000200015⟩
Article dans une revue hal-03915422 v1
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Genomic Instability Is Defined by Specific Tumor Microenvironment in Ovarian Cancer: A Subgroup Analysis of AGO OVAR 12 Trial

Jean-David Fumet , Emilie Lardenois , Isabelle Ray-Coquard , Philipp Harter , Florence Joly et al.
Cancers, 2022, 14 (5), pp.1189. ⟨10.3390/cancers14051189⟩
Article dans une revue hal-03769697 v1
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ZEB1 transcription factor promotes immune escape in melanoma

Maud Plaschka , Valentin Benboubker , Maxime Grimont , Justine Berthet , Laurie Tonon et al.
Journal for Immunotherapy of Cancer, 2022, 10 (3), pp.e003484. ⟨10.1136/jitc-2021-003484⟩
Article dans une revue hal-03769027 v1
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Heterogeneity and Functions of Tumor-Infiltrating Antibody Secreting Cells: Lessons from Breast, Ovarian, and Other Solid Cancers

Yasmine Lounici , Olivia Le Saux , Gabriel Chemin , Pauline Wajda , Sarah Barrin et al.
Cancers, 2022, 14 (19), pp.4800. ⟨10.3390/cancers14194800⟩
Article dans une revue hal-04882857 v1
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Neoadjuvant immune checkpoint inhibitors in cancer, current state of the art

Olivia Le Saux , Yasmine Lounici , Pauline Wajda , Sarah Barrin , Christophe Caux et al.
Critical Reviews in Oncology/Hematology, 2021, 157, pp.103172 -. ⟨10.1016/j.critrevonc.2020.103172⟩
Article dans une revue hal-03492630 v1
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Actualités en recherche en oncologie : l'essentiel du 4e Symposium International 2019 du Centre de Recherche en Cancérologie de Lyon

Frédéric Catez , Nicole Dalla Venezia , Jean-Jacques Diaz , Bertrand Dubois , Anthony Ferrari et al.
Bulletin du Cancer, 2020, 107 (1), pp.136-140. ⟨10.1016/j.bulcan.2019.12.002⟩
Article dans une revue hal-03004269 v1
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IFN-III is selectively produced by cDC1 and predicts good clinical outcome in breast cancer

Margaux Hubert , Elisa Gobbini , Coline Couillault , Thien-Phong Vu Manh , Anne-Claire Doffin et al.
Science Immunology, 2020, 5 (46), pp.eaav3942. ⟨10.1126/sciimmunol.aav3942⟩
Article dans une revue hal-02998632 v1
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Les avancées actuelles de l’immunothérapie dans le cancer de l’ovaire

Olivia Le Saux , Bertrand Dubois , Marc-Henri Stern , Magali Terme , Eric Tartour et al.
Bulletin du Cancer, 2020, 107, pp.465 - 473. ⟨10.1016/j.bulcan.2019.11.015⟩
Article dans une revue hal-03490307 v1
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Immunopathological characterization of ovarian teratomas associated with anti-N-methyl-D-aspartate receptor encephalitis

Aude Chefdeville , Isabelle Treilleux , Marie-Eve Mayeur , Coline Couillault , Géraldine Picard et al.
Acta Neuropathologica Communications, 2019, 7, pp.38. ⟨10.1186/s40478-019-0693-7⟩
Article dans une revue hal-02083563 v1

Genetic alterations and tumor immune attack in Yo paraneoplastic cerebellar degeneration

Mathilde Small , Isabelle Treilleux , Coline Couillault , Daniel Pissaloux , Géraldine Picard et al.
Acta Neuropathologica, 2018, 135 (4), pp.569-579. ⟨10.1007/s00401-017-1802-y⟩
Article dans une revue hal-04998090 v1
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Autocrine Adenosine regulates tumor polyfunctional CD73+CD4+ effector T cells devoid of immune checkpoints

Nicolas Gourdin , Marion Bossennec , Céline Rodriguez , Selena Vigano , Christelle Machon et al.
Cancer Research, 2018, 78 (13), pp.3604-3618. ⟨10.1158/0008-5472.CAN-17-2405⟩
Article dans une revue hal-02285966 v1

Hepatitis B Virus Blocks the CRE/CREB Complex and Prevents TLR9 Transcription and Function in Human B Cells

Issam Tout , Melissa Gomes , Michelle Ainouze , Marie Marotel , Timothee Pecoul et al.
Journal of Immunology, 2018, 201 (8), pp.2331-2344. ⟨10.4049/jimmunol.1701726⟩
Article dans une revue hal-04941080 v1

Intestinal dendritic cell licensing through Toll-like receptor 4 is required for oral tolerance in allergic contact dermatitis

Feriel Hacini-Rachinel , Mercedes Gomez de Agüero , Reem Kanjarawi , Ludovic Moro-Sibilot , Jean-Benoît Le Luduec et al.
Journal of Allergy and Clinical Immunology, 2018, 141 (1), pp.163-170. ⟨10.1016/j.jaci.2017.02.022⟩
Article dans une revue hal-02046249 v1
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Mélanome métastatique

Camille Fourneaux , Bertrand Dubois
Médecine/Sciences, 2018, 34 (10), pp.875-878. ⟨10.1051/medsci/2018219⟩
Article dans une revue hal-02970086 v1

Identification of Tertiary Lymphoid Structure-Associated Follicular Helper T Cells in Human Tumors and Tissues

Coline Couillault , Claire Germain , Bertrand Dubois , Hélène Kaplon
Methods in Molecular Biology, 2018, Methods in Molecular Biology, 1845, pp.205-222. ⟨10.1007/978-1-4939-8709-2_12⟩
Article dans une revue hal-04003929 v1

Mouse and Human Liver Contain Immunoglobulin A–Secreting Cells Originating From Peyer's Patches and Directed Against Intestinal Antigens

Ludovic Moro-Sibilot , Pascal Blanc , Morgan Taillardet , Emilie Bardel , Coline Couillault et al.
Gastroenterology, 2016, 151 (2), pp.311-323. ⟨10.1053/j.gastro.2016.04.014⟩
Article dans une revue hal-02046134 v1

Intradermal vaccination with un-adjuvanted sub-unit vaccines triggers skin innate immunity and confers protective respiratory immunity in domestic swine

Jean-Benoît Le Luduec , Sabine Debeer , Fabienne Piras , Christine Andréoni , Florence Boudet et al.
Vaccine, 2016, 34 (7), pp.914-922. ⟨10.1016/j.vaccine.2015.12.058⟩
Article dans une revue hal-01911477 v1

Plasmacytoid dendritic cells are dispensable for noninfectious intestinal IgA responses in vivo

Ludovic Moro-Sibilot , Sébastien This , Pascal Blanc , Amelien Sanlaville , Vanja Sisirak et al.
European Journal of Immunology, 2016, 46, pp.354--359. ⟨10.1002/eji.201545977⟩
Article dans une revue hal-01812673 v1
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Intradermal immunisation using the TLR3-ligand Poly (I:C) as adjuvant induces mucosal antibody responses and protects against genital HSV-2 infection

Emilie Bardel , Remi Doucet-Ladeveze , Cyrille Mathieu , Ali M. Harandi , Bertrand Dubois et al.
NPJ vaccines, 2016, 1, pp.16010. ⟨10.1038/npjvaccines.2016.10⟩
Article dans une revue hal-01911476 v1
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S1PR5 is pivotal for the homeostasis of patrolling monocytes.

Emilie Debien , Katia Mayol , Vincent Biajoux , Cécile Daussy , Mercedes Gomez de Aguero et al.
European Journal of Immunology, 2013, 43 (6), pp.1667-75. ⟨10.1002/eji.201343312⟩
Article dans une revue hal-00972078 v1

Regulatory T Cells Control Type I Food Allergy to Beta-Lactoglobulin in Mice

Reem Kanjarawi , Christophe Dercamp , Nathalie Etchart , Karine Adel-Patient , Jean-François Nicolas et al.
International Archives of Allergy and Immunology, 2011, 156 (4), pp.387 - 396. ⟨10.1159/000323940⟩
Article dans une revue hal-02645403 v1

Characterization of a CD44/CD122int memory CD8 T cell subset generated under sterile inflammatory conditions.

Florentin Martial Mbitikon-Kobo , Marc Vocanson , Marie-Cécile Michallet , Martine Tomkowiak , Anne Cottalorda et al.
Journal of Immunology, 2009, 182 (6), pp.3846-54. ⟨10.4049/jimmunol.0802438⟩
Article dans une revue inserm-00392005 v1

Dendritic cells rapidly recruited into epithelial tissues via CCR6/CCL20 are responsible for CD8+ T cell crosspriming in vivo.

Marie Le Borgne , Nathalie Etchart , Anne Goubier , Sergio A. Lira , Jean Claude Sirard et al.
Immunity, 2006, 24, pp.191-201. ⟨10.1016/j.immuni.2006.01.005⟩
Article dans une revue inserm-00000041 v1

Dynamics and function of Langerhans cells in vivo: dermal dendritic cells colonize lymph node areas distinct from slower migrating Langerhans cells.

Adrien Kissenpfennig , Sandrine Henri , Bertrand Dubois , Corinne Laplace-Builhé , Pierre Perrin et al.
Immunity, 2005, 22 (5), pp.643-54. ⟨10.1016/j.immuni.2005.04.004⟩
Article dans une revue hal-00165695 v1

Dendritic Cells Enhance the Differentiation of Naive B Cells into Plasma Cells In Vitro

Jérôme Fayette , Isabelle Durand , Jean-Michel Bridon , Christophe Arpin , Bertrand Dubois et al.
Scandinavian Journal of Immunology, 1998, 48 (6), pp.563-570. ⟨10.1046/j.1365-3083.1998.00471.x⟩
Article dans une revue hal-02474199 v1

The CSF-1R inhibitor Pexidartinib impacts dendritic cell differentiation through inhibition of FLT3 signaling and may antagonize the effect of durvalumab in patients with advanced cancer – results from a phase 1 study

Céline Rodriguez , Aurélien Voissiere , Axelle Nkodia , Carlos Alberto Gomez-Roca , Sylvie Chabaud et al.
26e congrès annuel de l’AFC à Toulouse, Nov 2023, Toulouse, France
Communication dans un congrès hal-04890819 v1

Spatial organization and prognostic impact of dendritic cell subsets in a large cohort of triple negative breast cancer patients

Elisa Gobbini , Margaux Hubert , Anne-Claire Doffin , Candice Sakref , Justine Berthet et al.
Club Francophone des Cellules Dendritiques, Dec 2021, Paris, France
Communication dans un congrès hal-04944901 v1

Complementary but distinct protective roles of breast tumor infiltrating IgG and IgA producing cells

Yasmine Lounici , Coline Couillault , Justine Berthet , Vincent Alcazer , Olivia Le Saux et al.
53rd Annual Meeting of the French Society for Immunology, Dec 2021, Paris, France
Communication dans un congrès hal-04968100 v1
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P11-05. Induction of CD8+ T cell mediated immune responses through skin and mucosa: identification of immunostimulatory versus tolerogenic dendritic cells

Bertrand Dubois , Mercedes Gomez de Agüero , Marie Le Borgne , Marie Gouanvic , Marc Vocanson et al.
AIDS Vaccine 2009, Oct 2009, Paris, France. pp.P150, ⟨10.1186/1742-4690-6-S3-P150⟩
Communication dans un congrès inserm-00663585 v1