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Bruno Le Pioufle

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  • IdHAL bruno-le-pioufle
  • ResearcherId : B-6951-2013
  • ORCID 0000-0002-0010-2475
  • Google Scholar : https://scholar.google.fr/citations?user=EdnD04cAAAAJ&hl=fr&oi=ao
  • IdRef : 076314057
  • ResearcherId : http://www.researcherid.com/rid/B-6951-2013

Presentation

**Bruno LE PIOUFLE, Professor at the Ecole Normale Supérieure Paris-Saclay** ================================================================================ *E.N.S. Paris-Saclay, 4 av. des sciences, 91190 Gif-sur-Yvette, France,* *Phone: 001 33 1 81875560, email: [send an email](https://hebergement.universite-paris-saclay.fr/biomis_d/?page_id=190)* **EDUCATION:** 1997: Accreditation to supervise research , University of PARIS 11 1991: French Ph.D., University of PARIS 11 **PROFESSIONAL EXPERIENCE:** Since 2020: Director of Institut d'Alembert (CNRS FR 3242, University Paris-Saclay) since 2007: Professor at ENS Cachan, (now ENS Paris-Saclay) 2005-2007: Director of LIMMS/CNRS IIS,UMI 2820, University of Tokyo, group of S. Takeuchi 1999: Professor à l’ENS de Cachan, Creation and Direction of BIOMIS group(1999-2005) 1997-1999: CNRS researcher at LIMMS, University of Tokyo, IIS, group of H. Fujita 1992-1997: Associate professor ar ENS Cachan **MAIN RESEARCH ACTIVITIES** B. Le Pioufle have been working since 1997 on the conception of bio-medical purpose microsystems. His main scientific concerns are 1) the conception of microfluidic biochips integrating biological or solid-state nanopores for the biosensing and 2) cell biochips. He spent 4 years at University of Tokyo, in the groups of H. Fujita, then in the group of S. Takeuchi. He was Director of LIMMS (International laboratory between CNRS and University of Tokyo). He worked in collaboration with S. Takeuchi on the conception of parallelized biochips for the screening on transmembrane molecules. He is also working on biochips for the cell analysis and treatment, and organ on chip. He is working on cell handling on a chip using dielectrophoresis, cell electroporation on a chip, microfluidics, surface functionalization of biochips.
**Bruno LE PIOUFLE, Professor at the Ecole Normale Supérieure Paris-Saclay** ================================================================================ *E.N.S. Paris-Saclay, 4 av. des sciences, 91190 Gif-sur-Yvette, France,* *Phone: 001 33 1 81875560, email: bruno.le-pioufle@ens-paris-saclay.fr* **EDUCATION:** 1997: Accreditation to supervise research , University of PARIS 11 1991: French Ph.D., University of PARIS 11 **PROFESSIONAL EXPERIENCE:** Since 2020: Director of [Institut d'Alembert](http://ida.ens-paris-saclay.fr/version-anglaise/ "Institut d'Alembert") (CNRS FR 3242, University Paris-Saclay) since 2007: Professor at ENS Cachan, (now ENS Paris-Saclay) 2005-2007: Director of LIMMS/CNRS IIS,UMI 2820, University of Tokyo, group of S. Takeuchi 1999: Professor à l’ENS de Cachan, Creation and Direction of BIOMIS group(1999-2005) 1997-1999: CNRS researcher at LIMMS, University of Tokyo, IIS, group of H. Fujita 1992-1997: Associate professor ar ENS Cachan **MAIN RESEARCH ACTIVITIES** B. Le Pioufle have been working since 1997 on the conception of bio-medical purpose microsystems. His main scientific concerns are 1) the conception of microfluidic biochips for the monitoring of membrane proteins and ion channels and 2) cell biochips. He spent 4 years at University of Tokyo, in the groups of H. Fujita, then in the group of S. Takeuchi. He was Director of LIMMS (International laboratory between CNRS and University of Tokyo). He worked in collaboration with S. Takeuchi on the conception of parallelized biochips for the screening on transmembrane molecules. He is also working on biochips for the cell analysis and treatment, and organ on chip. He is working on cell handling on a chip using dielectrophoresis, cell electroporation on a chip, microfluidics, surface functionalization of biochips. The main projects on which he has been working are 1) the study and conception of highly parallelized cell biochips for analysis (high throughput screening) or treatment (gene transfection on a chip) 2) the study and conception of biochips for ex-vivo (on a chip) analysis of physiological models 3) the design of biochips designed for the delivery of high amplitude electrical nanosecond pulses for the treatment of cells.

Publications

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Revealing the Friction Stress of Microalgae in Microfluidic Devices through Mechanofluorochromism

Lorenzo Casimiro , Rémi Métivier , Bruno Le Pioufle , Sakina Bensalem , Clémence Allain
Advanced Materials Interfaces, 2023, ⟨10.1002/admi.202300312⟩
Journal articles hal-04190604v1

Label-free and noninvasive analysis of microorganism surface epistructures at the single-cell level

Yu-Sheng Lin , Chen-Li Sun , Sung Tsang , Sakina Bensalem , Bruno Le Pioufle
Biophysical Journal, 2023, 122 (10), pp.1794-1806. ⟨10.1016/j.bpj.2023.04.012⟩
Journal articles hal-04103327v1

Focus on using nanopore technology for societal health, environmental, and energy challenges

Izadora Mayumi Fujinami Tanimoto , Benjamin Cressiot , Sandra Greive , Bruno Le Pioufle , Laurent Bacri
Nano Research, 2022, ⟨10.1007/s12274-022-4379-2⟩
Journal articles hal-03676129v1
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Bioimpedance single cell sensing of low and high density sickle erythrocytes using microfluidics

Tieying Xu , Maria Lizarralde-Iragorri , Benoit Charlot , Jean Roman , Olivier Français
Biosensors and Bioelectronics: X, 2022, 10, pp.100140. ⟨10.1016/j.biosx.2022.100140⟩
Journal articles hal-03650901v1

Dynamics of DNA Through Solid‐state Nanopores Fabricated by Controlled Dielectric Breakdown

Izadora Mayumi Fujinami Tanimoto , Jiayi Zhang , Benjamin Cressiot , Bruno Le Pioufle , Laurent Bacri
Chemistry - An Asian Journal, 2022, 17 (24), ⟨10.1002/asia.202200888⟩
Journal articles hal-04068157v1
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Selective Target Protein Detection Using a Decorated Nanopore into a Microfluidic Device

Izadora Mayumi Fujinami Tanimoto , Benjamin Cressiot , Nathalie Jarroux , Jean Roman , Gilles Patriarche
Biosensors and Bioelectronics, 2021, 183, pp.113195. ⟨10.1016/j.bios.2021.113195⟩
Journal articles hal-03223167v2
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A versatile microfluidic tool for the 3D culture of HepaRG cells seeded at various stages of differentiation

Manon Boul , Nassima Benzoubir , Antonietta Messina , Rasta Ghasemi , Ismail Ben Mosbah
Scientific Reports, 2021, 11, pp.14075. ⟨10.1038/s41598-021-92011-7⟩
Journal articles hal-03286077v1
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Impact of pulsed electric fields and mechanical compressions on the permeability and structure of Chlamydomonas reinhardtii cells

Sakina Bensalem , Dominique Pareau , Bertrand Cinquin , Olivier Français , Bruno Le Pioufle
Scientific Reports, 2020, 10, pp.2668. ⟨10.1038/s41598-020-59404-6⟩
Journal articles hal-02486263v1
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Oxidative stress activates red cell adhesion to laminin in sickle cell disease

Maria Alejandra Lizarralde-Iragorri , Sophie Lefevre , Sylvie Cochet , Sara El Hoss , Valentine Brousse
Haematologica, 2020, 106 (9), pp.haematol.2020.261586. ⟨10.3324/haematol.2020.261586⟩
Journal articles hal-02929195v1
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Electrorotation of single microalgae cells during lipid accumulation for assessing cellular dielectric properties and total lipid contents

Yu-Sheng Lin , Sung Tsang , Sakina Bensalem , Ching-Chu Tsai , Shiang-Jiuun Chen
Biosensors and Bioelectronics, 2020, 173, pp.112772. ⟨10.1016/j.bios.2020.112772⟩
Journal articles hal-03006108v1
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Characterization of red blood cell microcirculatory parameters using a bioimpedance microfluidic device

Tieying Xu , Maria A Lizarralde-Iragorri , Jean Roman , Rasta Ghasemi , Jean-Pierre Lefevre
Scientific Reports, 2020, ⟨10.1038/s41598-020-66693-4⟩
Journal articles hal-02872830v1

Characterization of sequentially-staged cancer cells using electrorotation

Claudia Trainito , Daniel Sweeney , Jaka Čemažar , Eva Schmelz , Olivier Français
PLoS ONE, 2019, 14 (9), pp.e0222289. ⟨10.1371/journal.pone.0222289⟩
Journal articles hal-02301212v1

Reticulocyte and red blood cell deformation triggers specific phosphorylation events

Pedro Moura , Maria Lizarralde Iragorri , Olivier Français , Bruno Le Pioufle , Johannes Dobbe
Blood Advances, 2019, 3 (17), pp.2653-2663. ⟨10.1182/bloodadvances.2019000545⟩
Journal articles hal-02289553v1
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Brownian Motion and Large Electric Polarizabilities Facilitate Dielectrophoretic Capture of Sub‐200 nm Gold Nanoparticles in Water

Clyde Midelet , Bruno Le Pioufle , Martinus Werts
ChemPhysChem, 2019, 20 (24), pp.3354-3365. ⟨10.1002/cphc.201900662⟩
Journal articles hal-02334475v1

Inducing reversible or irreversible pores in Chlamydomonas reinhardtii with electroporation: Impact of treatment parameters

Pierre Bodenes , Sakina Bensalem , Olivier Français , Dominique Pareau , Bruno Le Pioufle
Algal Research - Biomass, Biofuels and Bioproducts, 2019, 37, pp.124-132. ⟨10.1016/j.algal.2018.11.016⟩
Journal articles hal-01944176v1
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Solid-state nanopore easy chip integration in a cheap and reusable microfluidic device for ion transport and polymer conformation sensing

Jean Roman , Olivier Français , Nathalie Jarroux , Gilles Patriarche , Juan Pelta
ACS Sensors, 2018, 3 (10), pp.2129-2137. ⟨10.1021/acssensors.8b00700⟩
Journal articles hal-01891773v1

A microfluidic approach to study the effect of mechanical stress on erythrocytes in sickle cell disease

Maria Alejandra Lizarralde Iragorri , Sara El Hoss, , Valentine Brousse , Sophie Lefevre , Michael Dussiot
Lab on a Chip, 2018, 18 (19), pp.2975-2984. ⟨10.1039/C8LC00637G⟩
Journal articles hal-01875109v1
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From current trace to the understanding of confined media

Jean Roman , Bruno Le Pioufle , Loïc Auvray , Juan Pelta , Laurent Bacri
European Physical Journal E: Soft matter and biological physics, 2018, 41, pp.99. ⟨10.1140/epje/i2018-11709-5⟩
Journal articles hal-01882378v1

Understanding the mechanisms of lipid extraction from microalga Chlamydomonas reinhardtii after electrical field solicitations and mechanical stress within a microfluidic device

Sakina Bensalem , Filipa Lopes , Pierre Bodénès , Dominique Pareau , Olivier Français
Bioresource Technology, 2018, 257, pp.129 - 136. ⟨10.1016/j.biortech.2018.01.139⟩
Journal articles hal-01789219v1
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Structural changes of Chlamydomonas reinhardtii cells during lipid enrichment and after solvent exposure

Sakina Bensalem , Filipa Lopes , Pierre Bodénès , Dominique Pareau , Olivier Français
Data in Brief, 2018, 17, pp.1283 - 1287. ⟨10.1016/j.dib.2018.02.042⟩
Journal articles hal-01789908v1

Functionalized Solid-State Nanopore Integrated in a Reusable Microfluidic Device for a Better Stability and Nanoparticle Detection

Jean Roman , Nathalie Jarroux , Gilles Patriarche , Olivier Français , Juan Pelta
ACS Applied Materials & Interfaces, 2017, 9 (48), pp.41634 - 41640. ⟨10.1021/acsami.7b14717⟩
Journal articles hal-01661723v1

Monitoring of Microalgae Lipid Accumulation Using RF Open Ended Biosensor

Abdelhatif El Fellahi , Thierry Bore , Sakina Bensalem , Pierre Bodénès , Filipa Lopes
IEEE Sensors Letters, 2017, 1 (4), pp. 4500303. ⟨10.1109/LSENS.2017.2709082⟩
Journal articles hal-01587262v1
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Microdevice for studying the in situ permeabilization and characterization of Chlamydomonas reinhardtii in lipid accumulation phase

Pierre Bodénès , F. Lopes , D. Pareau , Olivier Français , B. Le Pioufle
Algal Research - Biomass, Biofuels and Bioproducts, 2016, 16, pp.357-367. ⟨10.1016/j.algal.2016.03.023⟩
Journal articles hal-01303998v1

The Electrorotation as a Tool to Monitor the Dielectric Properties of Spheroid During the Permeabilization

C. I. Trainito , Elsa Bayart , F. Subra , Olivier Français , B. Le Pioufle
Journal of Membrane Biology, 2016, ⟨10.1007/s00232-016-9880-7⟩
Journal articles hal-01284729v1

Electric pulses: a flexible tool to manipulate cytosolic calcium concentrations and generate spontaneous-like calcium oscillations in mesenchymal stem cells

Marie-Amelie de Menorval , Franck M. Andre , Aude Silve , Claire Dalmay , Olivier Français
Scientific Reports, 2016, 6, ⟨10.1038/srep32331⟩
Journal articles hal-01357904v1

Effects of Poloxamer 188 on red blood cell membrane properties in sickle cell anaemia

Barbara Sandor , Mickaël Marin , Claudine Lapouméroulie , Miklos Rabaï , Sophie Lefevre
British Journal of Haematology, 2016, 173 (1), pp.145 - 149. ⟨10.1111/bjh.13937⟩
Journal articles hal-01881668v1
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Nanoparticle Electrical Analysis and Detection with a Solid-state Nanopore in a Microfluidic Device

Jean Roman , Olivier Français , Nathalie Jarroux , Gilles Patriarche , Juan Pelta
Procedia Engineering, 2016, Proceedings of the 30th anniversary Eurosensors Conference – Eurosensors 2016, 4-7. Sepember 2016, Budapest, Hungary, 168, pp.1475-1478. ⟨10.1016/j.proeng.2016.11.425⟩
Journal articles hal-02006469v1

A generic and label free method based on dielectrophoresis for the continuous separation of microorganism from whole blood samples

Emilie Bisceglia , Myriam Cubizolles , Claudia Irene Trainito , Jean Berthier , Catherine Pudda
Sensors and Actuators B: Chemical, 2015, 212, pp.335-343. ⟨10.1016/j.snb.2015.02.024⟩
Journal articles hal-01121775v1
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Splenic retention of Plasmodium falciparum gametocytes to block the transmission of malaria

Julien Duez , John P. Holleran , Papa Alioune Ndour , Sasdekumar Loganathan , Pascal Amireault
Antimicrobial Agents and Chemotherapy, 2015, pp.AAC.05030-14. ⟨10.1128/AAC.05030-14⟩
Journal articles hal-01158996v1
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Microsystème dédié à l’étude de la polarisation diélectrique de microparticules dans le cadre de formation master recherche : application au micropositionnement 3D de cellules par force de diélectrophorèse

Rémi Sieskind , Claudia Trainito , Olivier Français , Bruno Le Pioufle
Journal sur l'enseignement des sciences et technologies de l'information et des systèmes, 2015, 14, http://dx.doi.org/10.1051/j3ea/2015007. ⟨10.1051/j3ea/2015007⟩
Journal articles hal-01122450v1

Monitoring the permeabilization of a single cell in a microfluidic device, through the estimation of its dielectric properties based on combined dielectrophoresis and electrorotation in-situ experiments

Claudia Irene Trainito , Olivier Français , Bruno Le Pioufle
Electrophoresis, 2015, ⟨10.1002/elps.201400482⟩
Journal articles hal-01116751v1

A biomimetic microfluidic chip to study the circulation and mechanical retention of red blood cells in the spleen

Julien Picot , Papa Alioune Ndour , Sophie D. Lefevre , Wassim El Nemer , Harvey Tawfik
American Journal of Hematology, 2015, ⟨10.1002/ajh.23941⟩
Journal articles hal-01113050v1

Reproducing topography and roughness of osteoconductive biomaterials in a microfluidic device

Eric Perrin , Olivier Français , Bruno Le Pioufle , Bertrand David
Computer Methods in Biomechanics and Biomedical Engineering, 2015, 18 (sup1), pp.2026-2027. ⟨10.1080/10255842.2015.1069567⟩
Journal articles hal-01222451v1

Analysis of pulsed electric field effects on cellular tissue with Cole–Cole model: Monitoring permeabilization under inhomogeneous electrical field with bioimpedance parameter variations

C.I. Trainito , Olivier Français , B. Le Pioufle
Innovative Food Science & Emerging Technologies / Innovative Food Science and Emerging Technologies , 2015, 29, pp.193-200/10.1016/j.ifset.2015.02.004. ⟨10.1016/j.ifset.2015.02.004⟩
Journal articles hal-01122453v1

How medium osmolarity influences dielectrophoretically assisted on-chip electrofusion

Feriel Sihem Hamdi , Olivier Français , Elisabeth Dufour-Gergam , Bruno Le Pioufle
Bioelectrochemistry, 2014, pp.42-46. ⟨10.1016/j.bioelechem.2014.05.004⟩
Journal articles hal-01026162v1

Low Temperature Irreversible Poly(DiMethyl) Siloxane Packaging of Silanized SU8 Microchannels: Characterization and Lab-on-Chip Application

Feriel Sihem Hamdi , M. Woytasik , Magdalèna Couty , Olivier Français , Bruno Le Pioufle
Journal of Microelectromechanical Systems, 2014, pp.ISSN 1057-7157. ⟨10.1109/JMEMS.2014.2331454⟩
Journal articles hal-01063867v1
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Manipulation and optical detection of colloidal functional plasmonic nanostructures in microfluidic systems

Martinus H. V. Werts , Florent Allix , Olivier Français , Céline Frochot , Laurent Griscom
IEEE Journal of Selected Topics in Quantum Electronics, 2014, 20, pp.6900613. ⟨10.1109/JSTQE.2013.2284549⟩
Journal articles hal-00961328v1
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Micro-organism extraction from biological samples using DEP forces enhanced by osmotic shock

Emilie Bisceglia , Myriam Cubizolles , Frederic Mallard , Francoise Vinet , Olivier Français
Lab on a Chip, 2013, 13 (5), pp.901-909. ⟨10.1039/c2lc41128h⟩
Journal articles hal-00785335v1

Study of the transmembrane potential distribution of cell pairs in a microfluidic device using polymer obstacles to initiate electrofusion

Feriel Sihem Hamdi , Olivier Français , Frédéric Subra , Wei Wang , Marion Woytasik
European Physical Journal: Applied Physics, 2013, 62 (01), pp.11202-11212. ⟨10.1051/epjap/2013120392⟩
Journal articles hal-00812130v1
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Microarray of non-connected gold pads used as high density electric traps for parallelized pairing and fusion of cells

Feriel S Hamdi , Olivier Français , Frederic Subra , Elisabeth Dufour-Gergam , Bruno Le Pioufle
Biomicrofluidics, 2013, 7, pp.044101. ⟨10.1063/1.4813062⟩
Journal articles hal-00861239v1

La mesure de la bio-impédance d'un végétal comme moyen d'introduire le domaine de la biologie dans une formation E.E.A.

Olivier Français , Bruno Le Pioufle
Journal sur l'enseignement des sciences et technologies de l'information et des systèmes, 2013, 12, 2013, pp.0018. ⟨10.1051/j3ea/2013018⟩
Journal articles hal-00934120v1

High-resolution analyses of cell fusion dynamics in a biochip

Guillaume Mottet , Bruno Le Pioufle , Lluis M. Mir
Electrophoresis, 2012, 33 (16), pp.2508-2515. ⟨10.1002/elps.201200112⟩
Journal articles hal-00738706v1
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A microfluidic device with removable packaging for the real time visualisation of intracellular effects of nanosecond electrical pulses on adherent cells

Claire Dalmay , M. A. de Menorval , Olivier Français , L. M. Mir , Bruno Le Pioufle
Lab on a Chip, 2012, 12 (22), pp.4709-15. ⟨10.1039/c2lc40857k⟩
Journal articles hal-00745203v1
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Activity Monitoring of Functional OprM Using a Biomimetic Microfluidic Device

Wei Wang , Laura Monlezun , Martin Picard , Philippe Benas , Olivier Français
Analyst, 2012, 137 (4), pp.847-852. ⟨10.1039/c2an16007b⟩
Journal articles hal-00739216v1

Discrete model combined with mimetic microfluidic chips to study cell growth in porous scaffold under flow conditions.

M. Chabanon , H. Duval , Olivier Français , Bruno Le Pioufle , E. Perrin
Computer Methods in Biomechanics and Biomedical Engineering, 2012, 15 (1), pp.25-26. ⟨10.1080/10255842.2012.713699⟩
Journal articles hal-00751801v1
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Design and realization of a microfluidic device devoted to the application of ultra-short pulses of electrical field to living cells

Claire Dalmay , Julien Villemejane , Vanessa Joubert , Olivier Français , Lluis M. Mir
Sensors and Actuators B: Chemical, 2011, 160 (1), pp.1573-1580. ⟨10.1016/j.snb.2011.09.009⟩
Journal articles hal-00738711v1
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A microfluidic biochip for the nanoporation of living cells

Claire Dalmay , Julien Villemejane , Vanessa Joubert , Aude Silve , Delia Arnaud-Cormos
Biosensors and Bioelectronics, 2011, 26 (12), pp.4649-4655. ⟨10.1016/j.bios.2011.03.020⟩
Journal articles hal-00674584v1

Solvatochromic dissociation of non-covalent fluorescent organic nanoparticles upon cell internalization

Marie Breton , Gaelle Prevel , Jean-Frederic Audibert , Robert Bernard Pansu , Patrick Tauc
Physical Chemistry Chemical Physics, 2011, 13 (29), pp.13268-13276. ⟨10.1039/c1cp20877b⟩
Journal articles hal-00739217v1
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A technique to design complex 3D lab on a chip involving multilayered fluidics, embedded thick electrodes and hard packaging. Application to dielectrophoresis and electroporation of cells.

Guillaume Mottet , Julien Villemejane , Luis M. Mir , Bruno Le Pioufle
Journal of Micromechanics and Microengineering, 2010, 20, pp.047001. ⟨10.1088/0960-1317/20/4/047001⟩
Journal articles hal-00592400v1
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Electro-Optical Imaging Microscopy of Dye-Doped Artificial Lipidic Membranes

Bassam Hajj , Sophie de Reguardati , Loic Hugonin , Bruno Le Pioufle , Toshihisa Osaki
Biophysical Journal, 2009, 97 (11), pp.2913-2921. ⟨10.1016/j.bpj.2009.08.055⟩
Journal articles hal-00599955v1

Ninety-six-well planar lipid bilayer chip for ion channel recording Fabricated by hybrid stereolithography

Hiroaki Suzuki , Bruno Le Pioufle , Shoji Takeuchi
Biomedical Microdevices, 2009, 11 (1), pp.17-22. ⟨10.1007/s10544-008-9205-4⟩
Journal articles hal-00599926v1

Multichannel Simultaneous Measurements of Single-Molecule Translocation in α-Hemolysin Nanopore Array

Toshihisa Osaki , Hiroaki Suzuki , Bruno Le Pioufle , Shoji Takeuchi
Analytical Chemistry, 2009, 81 (24), pp.9866-9870. ⟨10.1021/ac901732z⟩
Journal articles hal-00599956v1

Lipid Bilayer Microarray for Parallel Recording of Transmembrane Ion Currents

Bruno Le Pioufle , H. Suzuki , K. Tabata , H. Noji , S. Takeuchi
Analytical Chemistry, 2008, 80 (1), pp.328-332. ⟨10.1021/ac7016635⟩
Journal articles hal-00599949v1

Assembly of CdSe/ZnS nanocrystals on microwires and nanowires for temperature sensing

Peter Low , Bruno Le Pioufle , Beomjoon Kim , Christian Bergaud
Sensors and Actuators B: Chemical, 2008, 130 (1), pp.175-180. ⟨10.1016/j.snb.2007.07.123⟩
Journal articles hal-00599950v1

Perfusion culture of mammalian cells in microfluidic environments for tissue engineering applications 

Eric Leclerc , Bertrand David , Laurent Griscom , Bruno Lepioufle , Yasuyuki Sakai
La Houille Blanche - Revue internationale de l'eau, 2006, 3, pp.56-59. ⟨10.1051/lhb:200603008⟩
Journal articles hal-02149903v1
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Vacuum Casting to Manufacture a Plastic Biochip for Highly Parallel Cell Transfection

Matthieu Denoual , Y. Macé , Bruno Le Pioufle , Pascal Mognol , D. Castel
Measurement Science and Technology, 2006, 17, pp.3134-3140. ⟨10.1088/0957-0233/17/12/S03⟩
Journal articles hal-00739220v1

Constraining the connectivity of neuronal networks cultured on microelectrodes arrays with microfluidic techniques: a step towards neuron-based functional chips"

F Morin , N. Nishimura , L Griscom , Bruno Le Pioufle , H Fujita
Biosensors and Bioelectronics, 2006, 21 (7), pp.1093-1100
Journal articles hal-00739218v1

Perfusion culture of mammalian cells in microfluidic environments for tissue engineering applications.

E. Leclerc , B. David , L. Griscom , Bruno Le Pioufle , T. Fujii
La Houille Blanche - Revue internationale de l'eau, 2006, 3, pp.56-59
Journal articles hal-00090259v1

Study of Osteoblastic Cells in a Microfluidic Environment

E. Leclerc , B. David , L Griscom , Bruno Le Pioufle , T. Fujii
Biomaterials, 2006, 27 (4), pp.558-595. ⟨10.1016/j.biomaterials.2005.06.002⟩
Journal articles hal-00778216v1

Vacuum casting, a new answer to manufacture biomicrosystems

Matthieu Denoual , Pascal Mognol , Bruno Le Pioufle
Journal of Engineering Manufacture, 2005, 219 (9), pp.697-502. ⟨10.1243/095440505X32571⟩
Journal articles hal-00739222v1

Cell Cultures over Nanoneedle Fields

Matthieu Denoual , M. Chiral , Bruno Le Pioufle
Nanobiotechnology Journal, 2005, 1 (4), pp.389-394. ⟨10.1385/nbt:1:4:389⟩
Journal articles hal-00739221v1

Micromanipulation de particules polarisables par diélectrophorèse

Marie Frénéa , Bruno Le Pioufle
Revue Internationale de Génie Electrique, 2004, 7 (3-4), pp.419-431. ⟨10.3166/rige.7.419-431⟩
Journal articles hal-00794466v1

Parallel cell biochips: cell placement using dielectrophoresis or microfluidic effects

Bruno Le Pioufle , Marie Frénéa-Robin , A. Tixier
Comptes Rendus. Physique, 2004, 5 (5), pp.589-596
Journal articles hal-00141373v1

Positioning living cells on a high-density electrode array by negative dielectrophoresis

M. Frenea , S. P. Faure , Bruno Le Pioufle , P. Coquet , H. Fujita
Materials Science and Engineering: C, 2003, 23 (5), pp.597-603
Journal articles hal-00739225v1
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Biopuces pour le traitement électrique paraléllisé de cellules

Bruno Le Pioufle , M. Frénéa , A. Tixier
Journal sur l'enseignement des sciences et technologies de l'information et des systèmes, 2003, 2 (HORS SÉRIE 2), pp.6. ⟨10.1051/bib-j3ea:2003608⟩
Journal articles hal-00739226v1

Techniques for patterning and guidance of primary culture neurons on micro-electrode arrays

Laurent Griscom , Patrick Degenaar , Bruno Le Pioufle , Eiichi Tamiya , Hiroyuki Fujita
Sensors and Actuators B: Chemical, 2002, 83 (1-3), pp.15-21
Journal articles hal-00778213v1

Cell Placement and Neural Guidance Using a Three-Dimensional Microfluidic Array

L. Griscom , P. Degenaar , Bruno Le Pioufle , E. Tamiya , H. Fujita
Japanese Journal of Applied Physics, 2001, 40, pp.5485-5490
Journal articles hal-00778212v1

Effect of the composition and thermal annealing on the transformation temperatures of sputtered TiNi shape memory alloy thin films

Patrick Surbled , Catherine Clerc , Bruno Le Pioufle , Manabu Ataka , Hiroyuki Fujita
Thin Solid Films, 2001, 401 (1-2), pp.52-59
Journal articles hal-00739227v1
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A Method for Micrometer Resolution Patterning of Primary Culture Neurons for SPM Analysis

P. Degenaar , Bruno Le Pioufle , L. Griscom , A. Tixier , Y. Akagi
Journal of Biochemistry, 2001, 130, pp.367-376
Journal articles hal-00786168v1

Living cells captured on a bio-microsystem devoted to DNA injection

Bruno Le Pioufle , P. Surbled , H. Nagai , Y. Murakami , H. S. Chun
Materials Science and Engineering: C, 2000, 12 (1-2), pp.77-81
Journal articles hal-00739228v1

Characterization of sputtered TiNi shape memory alloy thin films

P. Surbled , C. Clerc , Bruno Le Pioufle , H. Fujita
Japanese Journal of Applied Physics, 1999, 38, pp.L1547-L1549. ⟨10.1143/JJAP.38.L1547⟩
Journal articles in2p3-00003942v1

Comportement non linéaire des générateurs électrochimiques associés aux convertisseurs statiques. Détection de l'état de charge

Bruno Le Pioufle , J. F. Fauvarque , P. Delalande
European Physical Journal: Applied Physics, 1998, 2 (03), pp.257-265. ⟨10.1051/epjap:1998191⟩
Journal articles hal-00778215v1

COMPARISON OF CONTROL STRATEGIES TO MINIMIZE THE TORQUE RIPPLE OF A SWITCHED RELUCTANCE MACHINE

H. Cailleux , Bruno Le Pioufle , B. Multon
Electric Machines and Power Systems, 1997, 25 (10), pp.1103-1118. ⟨10.1080/07313569708955800⟩
Journal articles hal-00778210v1

Experimental nonlinear torque control of a permanent-magnet synchronous motor using saliency

D. Grenier , L. A. Dessaint , O. Akhrif , Y. Bonnassieux , Bruno Le Pioufle
IEEE Transactions on Industrial Electronics, 1997, 44 (5), pp.680-687. ⟨10.1109/41.633471⟩
Journal articles hal-00778211v1
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Modélisation et commande non linéaire en couple d'une machine à réluctance variable à double saillance

H. Cailleux , Bruno Le Pioufle , Bernard Multon
Journal de Physique III, 1996, 6 (1), pp.55-75. ⟨10.1051/jp3:1996114⟩
Journal articles jpa-00249447v1

Onduleur MLI pour servomoteur synchrone: minimisation des pulsations de couple

J.-F. Liebaut , Bruno Le Pioufle
RGE, 1994, 10
Journal articles hal-00778217v1

COMPARISON OF SPEED NONLINEAR CONTROL STRATEGIES FOR THE SYNCHRONOUS SERVOMOTOR

Bruno Le Pioufle
Electric Machines and Power Systems, 1993, 21 (2), pp.151-169. ⟨10.1080/07313569308909644⟩
Journal articles hal-00778214v1
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A robust total compensation algorithm for the torque control of a synchronous servomotor

Bruno Le Pioufle , G. Georgiou , J.-P. Louis
Journal de Physique III, 1992, 2 (1), pp.129-144. ⟨10.1051/jp3:1992115⟩
Journal articles jpa-00248724v1
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Commande non linéaire en vitesse d'un servomoteur synchrone avec calcul de trajectoire et estimation du couple résistant

Bruno Le Pioufle , G. Georgiou
Journal de Physique III, 1992, 2 (10), pp.1905-1924. ⟨10.1051/jp3:1992221⟩
Journal articles jpa-00248854v1
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Application des commandes non linéaires pour la régulation en vitesse ou en position de la machine synchrone autopilotée

Bruno Le Pioufle , G. Georgiou , J.-P. Louis
Revue de Physique Appliquée, 1990, 25 (6), pp.517-526. ⟨10.1051/rphysap:01990002506051700⟩
Journal articles jpa-00246214v1
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Self-organisation of human hepatocytes into hepatic cords on a radially perfused microfluidic device

A. Rajendran , Sakina Bensalem , Antonietta Messina , Nassima Benzoubir , Rasta Ghasemi
Micro Physiological System World Summit, Jun 2023, Berlin, Germany. pp.343
Conference papers hal-04466044v1

On-chip differentiation of radially vascularized hepatic cords mimicking the liver lobule

Alan Raj Jeffrey Rajendran , Sakina Bensalem , Antonietta Messina , Nassima Benzoubir , Rasta Ghasemi
Transducers, Jun 2023, Kyoto, Japan
Conference papers hal-04466234v1

Monolithic co-culture system for the gut-liver interaction study integrating paracellular barrier function assay

Ryuya Kida , Alan Raj Jeffrey Rajendran , Mamiko Tsugane , Jean-Charles Duclos-Vallée , Maxime Mahé
MicroTAS, Oct 2023, Katowice, Poland
Conference papers hal-04466148v1

Capture and characterization of extracellular vesicles by dielectrophoresis

Charlotte Neel , Jean‐frédéric Audibert , Sameh Obeid , Rasta Ghasemi , Sakina Bensalem
MicroTAS, Oct 2023, Katowice, Poland
Conference papers hal-04466195v1
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Applying successive mechanical stresses on circulating cells using microfluidic vascular network to assess sickled red blood cells rigidity

Tieying Xu , Maria A. Lizarralde-Iragorri , Olivier Français , Wassim El Nemer , Bruno Le Pioufle
MicroTAS, 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Oct 2022, Hangzhou, China
Conference papers hal-03831982v1
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A microfluidic device to statistically determine the distribution of sickle red cell subpopulations using bioimpedance

Tieying Xu , Maria A Lizarralde-Iragorri , Jean Roman , Emile Martincic , Valentine Brousse
Transducers, 2021, on-line, France
Conference papers hal-03260796v1
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Spherocytes flow behaviours in microrestriction, compared by normal red blood cells of different heat treatment levels

Tieying Xu , Maria Lizarralde Iragorri , Jean Roman , Emile Martincic , Valentine Brousse
MicroTAS 2021, Oct 2021, Palm Springs, United States
Conference papers hal-03821199v1

Two-Dimensionally Arrayed Double-Layer Electrode Device Which Enables Reliable and High-Throughput Electrorotation

Taku Tsuchiya , Yuki Okamoto , Frederic Marty , Ayako Mizushima , Agnes Tixier-Mita
2021 IEEE 34th International Conference on Micro Electro Mechanical Systems (MEMS), Jan 2021, Gainesville, United States. pp.486-489, ⟨10.1109/MEMS51782.2021.9375219⟩
Conference papers hal-03653496v1
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Different miniaturization systems of electrical biosensing and data acquisition during biological cell transiting within vessel size microchannel

Tieying Xu , Maria Lizarralde Iragorri , Jean Roman , Emile Martincic , Valentine Brousse
25th International Conference on Miniaturized Systems for Chemistry and Life Sciences ( MicroTAS 2021 ), Oct 2021, Palm Springs, United States
Conference papers hal-03821200v1
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Nanoparticle detection by solid state nanopore integrated into a reusable microfluidic device

Izadora Mayumi Fujinami Tanimoto , Benjamin Cressiot , Jean Roman , Nathalie Jarroux , Gilles Patriarche
MicroTAS, Oct 2020, on-line, France
Conference papers hal-03031395v1
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Electrical Sensing of sickled red blood cells subpopulations in microfluidic device

Tieying Xu , Maria A Lizarralde-Iragorri , Jean Roman , Emile Martincic , Valentine Brousse
MicroTAS, Oct 2020, on-line, France
Conference papers hal-03078878v1
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Characterizing single sinonasal squamous cell carcinoma using dielectrophoresis and electrorotation

Thao N P Mai , Sakina Bensalem , Bénédicte Thiebot , Philippe Manivet , Juan Pelta
MicroTAS, Oct 2020, on-line, France
Conference papers hal-03078871v1
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Monitoring the growthphases of microalgae using straightforward dielectrophoresis measurements

Yu-Sheng Lin , Bruno Le Pioufle , Hsiang-Yu Wang
MicroTAS, Oct 2020, on-line, France
Conference papers hal-03078861v1
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Sensing of Oxygen Concentration in a Microfluidic Device mimicking Liver 3D Microarchitecture

Manon Boul , Satomi Matsumoto , Marie Shinohara , Yasuyuki Sakai , Teruo Fujii
MicroTAS, Oct 2019, Basel, Switzerland
Conference papers hal-02387492v1

Puce microfluidique instrumentée pour la caractérisation HyperFréquence de fluides par spectroscopie diélectrique

Houssein Mariam , Patrick Poulichet , Hakim Takhedmit , Rousseau Lionel , Bruno Le Pioufle
C2i 2019 : 8ème Colloque Interdisciplinaire en Instrumentation, Jan 2019, Talence, France
Conference papers hal-02151546v1
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Electrical Detection of the Mechanical Alteration of Sickling Red Blood Cells within a Microfluidic Capillary Network

Xu Tieying , Maria Lizarralde , Jean Roman , Wassim El Nemer , Bruno Le Pioufle
MicroTAS, Oct 2019, Basel, Switzerland
Conference papers hal-02387976v1

Characterization of Chlamydomonas Reinhardtii's cell wall and membrane permeability after PEF treatment and mechanical compressions within a microfluidic device

Sakina Bensalem , Pierre Bodenes , Olivier Français , Dominique Pareau , Filipa Lopes
3rd World Congress on Electroporation, Sep 2019, Toulouse, France
Conference papers hal-02285033v1
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Z-Axis Controllable Mille-Feuille electrode electrorotation device utilizing levitation effect

Yuki Okamoto , Taku Tsuchiya , Charles Moslonka , Yu-Sheng Lin , Sung Tsang
Transducers 2019 - EUROSENSORS XXXIII, Jun 2019, Berlin, Germany. ⟨10.1109/transducers.2019.8808820⟩
Conference papers hal-02151887v1
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Microfluidic device using reusable parylen-pdms packaging for the red blood cell transit time analysis in mechanical constrictions, using impedance measurement

Xu Tieying , Maria Lizarralde , Wassim El Nemer , Bruno Le Pioufle , Olivier Français
MicroTAS, Nov 2018, Kaohsiung, Taiwan
Conference papers hal-01972640v1
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Using dielectrophoresis and electrorotation techniques to assess the dielectric properties of Scenedesmus Abundans at different growth states

Yu-Sheng Lin , Sung Tsang , Sakina Bensalem , Filipa Lopes , Chen-Li Sun
microTAS, Nov 2018, Kaohsiung, Taiwan
Conference papers hal-01959748v1

Comparison of serial and parallelized microfluidic structures mimicking hepatic cords and liver sinusoids on a chip

Manon Boul , Nassima Benzoubir , Nassim Arouche , Rasta Ghasemi , Jean-Pierre Lefevre
Organ-on-a-Chip & Tissue-on-a-Chip EUROPE 2018, Jun 2018, Rotterdam, Netherlands
Conference papers hal-01991331v1
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Effects of biomolecules on the electrokinetics of colloidal nanoparticles in liquid suspension

Clyde Midelet , J.-Y. Lin , Sung Tsang , Chen-Li Sun , Johanna Midelet
SPIE BIOS, Jan 2017, San Francisco, CA, United States. pp.100780T, ⟨10.1117/12.2252470⟩
Conference papers hal-01501667v1
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Microwave Sensor within a Microfluidic Chip for Biological Applications

Abdelhatif El Fellahi , Thierry Bore , Lionel Rousseau , Bruno Le Pioufle , Olivier Français
Eurosensors 2017, Sep 2017, Paris, France. pp.1-4, ⟨10.3390/proceedings1040523⟩
Conference papers hal-01592115v1
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Dielectric Characterisation of Single Microalgae Cell Using Electrorotation Measurements

Yu-Sheng Lin , Sung Tsang , Rasta Ghasemi , Sakina Bensalem , Olivier Français
Eurosensors 2017, Sep 2017, Paris, France. pp.543 - 6, ⟨10.3390/proceedings1040543⟩
Conference papers hal-01592123v1
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Monitoring Biological Cell Flow within a Mimicking Capillary Device with Impedance Measurement

Tieying Xu, , Maria Lizarralde, , Wassim El Nemer , Bruno Le Pioufle , Olivier Français
Eurosensors 2017, Sep 2017, Paris, France. pp.3 - 6, ⟨10.3390/proceedings1040517⟩
Conference papers hal-01592142v1

Mechanical and Electrical sensing of single biological cell properties within microfluidic devices

Bruno Le Pioufle , Olivier Français
NEMS (Nano Engineering Molecular Systems), Apr 2017, Los-Angeles, United States
Conference papers hal-01515021v1
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RF characterization of intracellular microalgae lipids

Abdelhatif El Fellahi , Thierry Bore , Pierre Bodénès , Sakina Bensalem , Bruno Le Pioufle
30th anniversary Eurosensors Conference, Sep 2016, Budapest, Hungary. pp.1287-1290, ⟨10.1016/j.proeng.2016.11.449⟩
Conference papers hal-01368312v1

Nanoparticle electrical analysis and detection with a solid-state nanopore in a microfluidic device

Jean Roman , Olivier Français , Nathalie Jarroux , Gilles Patriache , Juan Pelta
Eurosensors 2016, Sep 2016, Budapest, Hungary
Conference papers hal-01390031v1

SU-8 microchannels for live cell dielectrophoresis improvements

Lionel Rousseau , Gaelle Bazin Lissorgues , Fikar Pavel , Olivier Français , Bruno Le Pioufle
DTIP 2015, Apr 2015, Montpellier, France
Conference papers hal-01159000v1

In situ and real time electroporation of a lipid producing microalgae in a microfluidic device

Pierre Bodénès , Sakina Bensalem , Filipa Lopes , Dominique Pareau , Olivier Français
Algae Europe 2015, Dec 2015, Lisbonne, Portugal
Conference papers hal-01275167v1

First in vivo results of an innovative sensor to detect stent-related complications

Franz Bozsak , Bruno Carreel , Pierluca Massina , Myline Cottance , Olivier Français
ICI 2015, Dec 2015, Tel-Aviv, Israel
Conference papers hal-01275165v1

Microfluidic devices for the cell sensing and treatment

Olivier Français , Bruno Le Pioufle
GLEAM'15, Jun 2015, Cachan, France
Conference papers hal-01222696v1

A Microfluidic Device for the Real-Time Characterization of Lipid Producing Algae Cell Population Submitted to a Pulsed Electric Field

Pierre Bodénès , Filipa Lopes , Dominique Pareau , Olivier Français , Bruno Le Pioufle
1st World Congress on Electroporation and Pulsed Electric Fields in Biology, Medicine and Food & Environmental Technologies, Sep 2015, Portorož, Slovenia. pp.409-413, ⟨10.1007/978-981-287-817-5_89⟩
Conference papers hal-01222446v1

Electrorotation as a Versatile Tool to Estimate Dielectric Properties of Multi-scale Biological Samples: from Single Cell to Spheroid Analysis

Claudia Irene Trainito , Emilie Bayart , Emilie Bisceglia , Frédéric Subra , Olivier Français
1st World Congress on Electroporation and Pulsed Electric Fields in Biology, Medicine and Food & Environmental Technologies, Sep 2015, Portoroz, Slovenia. pp.75-78
Conference papers hal-01222447v1

Etude et mise en oeuvre d’un microsystème fluidique pour la caractérisation diélectrique de cellules biologiques par électrorotation

Olivier Français , Bruno Le Pioufle , Claudia Trainito
Symposium de Génie Electrique, Jul 2014, Cachan, France
Conference papers hal-01076066v1

A microfluidic device to study red blood cell deformability

Wassim El Nemer , Papa Alioune Ndour , Sophie D. Lefevre , Harvey Tawfik , Julien Picot
4th European Conference on Microfluidics, Dec 2014, Limerick, Ireland
Conference papers hal-01113061v1

Microsystème dédié à l’étude de la polarisation diélectrique de micro-particules dans le cadre de formation master recherche : application au micro-positionnement 3D de cellules par force de diélectrophorèse

Rémi Sieskind , Claudia Trainito , Olivier Français , Bruno Le Pioufle
CETSIS 2014 : Enseignement des Technologies et de Sciences de l'Information et des Systèmes, Oct 2014, Besançon, France
Conference papers hal-01085282v1

Reproducing topography and roughness of osteoconductive materials in a microfluidic device for bone tissue engineering

Bertrand David , Eric Perrin , Lazaar Mélanie , Chabanon Morgan , Bruno Le Pioufle
4th European Conference on Microfluidics, Dec 2014, Limerick, Ireland
Conference papers hal-01096932v1

Monitoring in real time the dielectric properties of a single cell combining dielectrophoresis and electrorotation experiments in a microfluidic device : towards electropermeabilization analysis

Claudia Trainito , Olivier Français , Bruno Le Pioufle
Dielectrophoresis 2014, Jul 2014, Londres, United Kingdom
Conference papers hal-01026163v1
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A microfluidic device to determine dielectric properties of a single cell : a combined dielectrophoresis and electrorotation technique

Claudia Trainito , Olivier Français , Bruno Le Pioufle
4th European Conference on Microfluidics, Dec 2014, Limerick, Ireland
Conference papers hal-01096921v1

Apport des microtechnologies pour l’étude des propriétés diélectriques cellulaires : application au tri et à la capture de cellules biologiques en environnement microfluidique

Olivier Français , Bruno Le Pioufle
Congrès Annuels conjoints de la Société Français d'Immunologie (SFI) et de l'Association Française de Cytométrie (AFC), Nov 2014, Lille, France
Conference papers hal-01085273v1

Micro-nanotechnologies pour l’analyse et le traitement parallèle de cellules ou de protéines sur puce

Claire Dalmay , Emilie Bisceglia , Feriel Hamdi , Olivier Français , Bruno Le Pioufle
Symposium de Génie Electrique, Jul 2014, Cachan, France
Conference papers hal-01076067v1

Detection of Micro-Beads by Impedance Cytometry - Towards a Wholly Integrated Electronic Device for Biological Cells Applications

Agnes Tixier , Takuya Takahashi , Hiroyuki Fujita , H. Toshiyoshi , Isao Mori
Symposium on Design, Test, Integration ans Packaging of MEMS/MOEMS, Apr 2014, Cannes, France. pp.1-6
Conference papers hal-00987015v1

Compressively-Stressed Test Structures for Opaque Micro-Structures Releasing Visualization

Agnes Tixier , E. Lebrasseur , T. Takahashi , Olivier Français , Bruno Le Pioufle
International Conference on Microelectronic Test Structures, Mar 2014, Udine, Italy. pp.170-173
Conference papers hal-00987105v1

Insertion of functional proteins into bilayer lipid membrane using a cell-free expression system

Angélique Coutable , Vincent Noireaux , Bruno Lepioufle , Olivier Français , Christophe Vieu
57. Annual Meeting of the Biophysical Society, Feb 2013, Philadelphie, Pennsylvanie, United States. pp.548A, ⟨10.1016/j.bpj.2012.11.3039⟩
Conference papers hal-01268382v1

La mesure de la bio-impédance d'un végétal comme moyen d'introduire le domaine de la biologie dans une formation E.E.A.

Olivier Français , Bruno Le Pioufle
Colloque sur l'Enseignement des Technologies et des Sciences de l'Information et des Systèmes (CETSIS), Mar 2013, Caen, France. pp.199 - 203
Conference papers hal-00804673v1

Quenched fluorescence and enhanced resonant light scattering in molecular plasmonic assemblies

Martinus H. V. Werts , Matthieu Loumaigne , Julien R. G. Navarro , A. Débarre , Laurent Griscom
Molecular Plasmonics 2013, May 2013, Jena, Germany
Conference papers hal-00877127v1

Quenched fluorescence and enhanced resonant light scattering in molecular plasmonic assemblies

Martinus H. V. Werts , Matthieu Loumaigne , Julien R. G. Navarro , Anne Débarre , Laurent Griscom
International Conference on Photochemistry 2013, Jul 2013, Belgium
Conference papers hal-00877131v1
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Optical microscopy and spectroscopy of analyte-sensitive functionalized gold nanoparticles in microfluidic systems

Martinus H. V. Werts , Vincent Raimbault , Matthieu Loumaigne , Laurent Griscom , Olivier Français
Proc. SPIE 2013, 8595, 85950W, Feb 2013, United States. pp.85950W, ⟨10.1117/12.2001608⟩
Conference papers hal-00809421v2

Design and use of microfluidic devices for the real time monitoring of micro/nanopulses effect on cells

Bruno Le Pioufle , Claire Dalmay , Olivier Français
Bioelectrochemistry 2013, Mar 2013, Bochum, Germany. pp.80
Conference papers hal-00805500v1

High Density Cell Electrofusion on Chip Using an Array of Non-Connected Metallic Pads

Feriel Hamdi , Wei Wang , Frédéric Subra , Elisabeth Dufour-Gergam , Olivier Français
Biodevices, 2013, Barcelone, Spain, Spain. pp.68-72
Conference papers hal-00790205v1

Micro-fluidic channel integration on thick-SOI LSI device for cells analyses

Agnes Tixier , Isao Mori , T. Takahashi , Olivier Français , Bruno Le Pioufle
Sensor Symposium 2013, Nov 2013, Sendaï, Japan. pp.320-325
Conference papers hal-00987092v1

In vitro and in silico study of cell growth in porous scaffold under dynamic flow

M. Chabanon , H. Duval , Olivier Français , Bruno Le Pioufle , E. Vennat
3rd TERMIS World Congress 2012 - Vienna, Austria, Sep 2012, Vienna, Austria. pp.340-341
Conference papers hal-00741428v1
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Dielectrophoretic separation of blood pathogens ou Bacterial extraction from biological samples using DEP forces

Emilie Bisceglia , Myriam Cubizolles , Frédéric Mallard , Olivier Français , Bruno Le Pioufle
lab on a chip world congress, Sep 2012, San Diego, United States. pp.1
Conference papers hal-00786577v1

From fluorescence quenching by metal nanoparticles to enhanced spectroscopic detection in microfluidic volumes

Martinus H. V. Werts , Julien R. G. Navarro , Laurent Griscom , Olivier Français , Bruno Le Pioufle
1st International Conference on Enhanced Spectroscopy, Oct 2012, Porquerolles, France
Conference papers hal-00753361v1
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Self control of cell electroporation by dielectrophoresis transition

Fériel Hamdi , Olivier Français , Marion Woytasik , Elisabeth Dufour-Gergam , Bruno Le Pioufle
Nanobiotech, 2011, Montreux, Switzerland
Conference papers hal-00739183v1
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Array of Metallic Singularities for the high density cell Placement on a Microfluidic Chip

Claire Dalmay , Olivier Français , Bruno Le Pioufle
MMB, 2011, Lucerne, Switzerland
Conference papers hal-00739187v1
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Positioning and orientation of adherent cells in a microfluidic chip using the micro patterning of a parylen-C-film

Claire Dalmay , Yung-Yung Lai , Laurent Griscom , Olivier Français , Bruno Le Pioufle
biodevices, 2011, Rome, Italy
Conference papers hal-00739185v1
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Towards a Statistical Description of Experimental Data for Detection - Estimation problems in DNA translocations trhough nanopores

S Michelet , J-P Barbot , Olivier Français , P.Y. Joubert , Pascal Larzabal
BIOSIGNALS, 2011, Roma, Italy
Conference papers hal-00739181v1

Dispositifs microfluidiques pour l'exposition et l'observation de cellules biologiques exposées à des impulsions électriques nanosecondes

Marie-Amélie de Ménorval , Franck Andre , Aude Silve , Claire Dalmay , Olivier Français
Journées Nationales des Nanotechnologies et des Nanosciences, J3N, Nov 2011, Strasbourg, France. pp.1
Conference papers hal-00933138v1
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A Microfluidic Biochip Dedicated to Highly Parallelized Electrofusion

Feriel Hamdi , Olivier Français , Julien Villemejane , M Woytasik , Claire Dalmay
MMB, 2011, Lucerne, Switzerland
Conference papers hal-00739182v1
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Insulated gold micro singularities for high density cell trapping based on dielectrophoresis

Claire Dalmay , Olivier Français , Frédéric Subra , Bruno Le Pioufle
Nanobiotech, 2011, Montreux, Switzerland
Conference papers hal-00739186v1

Development and uses of a microfluidic chamber to apply microsecond or nanosecond electric pulses and to visualize biological effects induced.

M.A. de Menorval , F Andre , Aude Silve , Claire Dalmay , Olivier Français
PLIC - Electroporation based Technologies and Treatments, 2011, Lubjana, Slovenia
Conference papers hal-00739184v1

Development and uses of a microfluidic chamber to apply microsecond or nanosecond electric pulses and to visualize biological effects induced

Marie-Amélie de Ménorval , Franck André , Aude Silve , Claire Dalmay , Olivier Français
Electroporation based Technologies and Treatments, Nov 2011, Ljubljana, Slovenia. pp.1
Conference papers hal-00933139v1

Development and uses of a microfluidic chamber to apply microsecond and nanosecond electric pulses and to visualize biological effects induced

Marie-Amélie de Ménorval , Franck M. André , Aude Silve , Claire Dalmay , Olivier Français
Pôle Lorrain de l'Ingéniérie du Cartilage, Sep 2011, Nancy, France. pp.1
Conference papers hal-00933141v1

Thick Electrode Biochip for in Vitro Studies of the Nanoporation of Living Cells

Claire Dalmay , J Villemejane , Olivier Français , M Woytasik , E Dufour-Gergam
Microfluidics, 2010, Toulouse, France
Conference papers hal-00739191v1

A High Density Microfluidic Device for Cell Pairing and Electrofusion

N Pham Van , J Villemejane , F Hamdi , G Mottet , Claire Dalmay
Eurosensors, 2010, Linz, Austria
Conference papers hal-00739189v1
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A Rupture Detection Algorithm for the DNA Translocation Detection Though Biological Nanopore

Toshihisa Osaki , Jean-Pierre Barbot , Ryuji Kawano , Hirotaka Sasaki , Olivier Français
Eurosensors, 2010, Linz, Austria
Conference papers hal-00739190v1

Nanomanipulation of living cells on a chip using electric field: general concepts and microdevices

J Villemejane , G Mottet , Olivier Français , Jp Lefèvre , M Woytasik
DELTA, 2010, Ho-shi-minh, Vietnam
Conference papers hal-00739188v1

Electro-Optical Imaging Microscopy of Dye Doped Lipid Bilayer

B. Hajj , S. de Reguardati , L. Hugonin , T. Osaki , H. Suzuki
2009 Conference on Lasers and Electro-Optics and Quantum Electronics and Laser Science Conference, 2009, Germany. pp.3-4
Conference papers hal-00795108v1

Nanosecond electric pulses-induced enhancement of reporter gene expression after electrotransfer in skeletal muscle in vivo

J Villemejane , V. Joubert , Olivier Français , Bruno Le Pioufle , Lm Mir
Int. Bioelectric Symposium, 2009, Paris, France
Conference papers hal-00739192v1

High Density Cell Microarray Based on Dielectrophoresis Traps Induced by a Matrix of Singularities

Olivier Français , A Ayina , J Villemejane , L Rousseau , L Mir
MicroTAS, 2009, Paris, North Korea
Conference papers hal-00739196v1

Fast concentration gradient generator on a cell biochip for toxicology applications

O Francais , Olivier Français , A Dimitracopoulos , Jp Lefevre , F Subra
MicroTAS, 2009, Paris, France
Conference papers hal-00739195v1

3D field focusing and defocusing geometries for cell trapping on a chip

Olivier Français , G Mottet , A Ayina , Bruno Le Pioufle
DTIP, 2009, Roma, Italy
Conference papers hal-00739193v1

Digital concentration gradient generators on a microfluidic chip

Olivier Français , B Mahe , A Dimitracopoulos , Marie-Caroline Jullien , Jp Lefevre
DTIP, 2009, Rome, Italy
Conference papers hal-00739194v1

Insulated Liquid Electrodes in a microfluidic chip for the electroporation of living cells

J Villemejane , G Mottet , Olivier Français , J.P. Lefevre , L.M. Mir
European Conference on Microfluidics, 2008, Bologna, Italy
Conference papers hal-00739197v1

A complete process to make a lab on a chip with complex fluidics and thick electrodes for biological applications

G Mottet , J Villemejane , J.P. Lefevre , Bruno Le Pioufle
European Conference on Microfluidics, 2008, Bologne, Italy
Conference papers hal-00739199v1

Multichannel Nanopore for High Throughput Single Molecule Detection

T Osaki , H Suzuki , Bruno Le Pioufle , S Takeuchi
MicroTAS, 2008, North Korea
Conference papers hal-00739198v1

High-throughput single-cell electroporation microchip with three dimensional si microelectrodes for gene transfection

Y. H. Cho , S. W. Lee , Bruno Le Pioufle , N. Takama , S. Takeuchi
Transducers '07 & Eurosensors Xxi, Digest of Technical Papers, Vols 1 and 2, 2007, France. pp.U474-U475
Conference papers hal-00795167v1

Selecting an electrode structure for cell sorting by differential dielectric affinity

Marie Frénéa-Robin , Julie Laforet , G. Robin , Bruno Le Pioufle , Laurent Nicolas
29th IEEE EMBC, Aug 2007, Lyon, France. pp.6311-6314, ⟨10.1109/IEMBS.2007.4353798⟩
Conference papers hal-00412972v1

Nanoneedle fields for biological interaction with cells

Matthieu Denoual , Magali Chiral , Olivier de Sagazan , Bruno Le Pioufle
Proc. of Micro Total Analysis System (uTAS), Japan, 2006, 2006, Japan. pp 1-9
Conference papers hal-00986481v1

Surface engineering of microfluidic systems for cellular biochips

L. Griscom , G. Legeay , Bruno Le Pioufle
2005 3rd IEEE/EMBS Special Topic Conference on Microtechnology in Medicine and Biology, 2005, China. pp.194-197, ⟨10.1109/mmb.2005.1548424⟩
Conference papers hal-00795194v1

Investigation of human hepatoma cell line in microfluidic devices

E. Leclerc , L. Griscom , Bruno Le Pioufle , C. Guguen-Guillouzo , A. Corlu
2005 3rd IEEE/EMBS Special Topic Conference on Microtechnology in Medicine and Biology, 2005, Shanghai, China. pp.385-388, ⟨10.1109/mmb.2005.1548482⟩
Conference papers hal-00795183v1

Vacuum casting of low-cost polymer microstructures for bio-chemical microsystems applications

Matthieu Denoual , S. Prioux , Y. Mace , Pascal Mognol , Bruno Le Pioufle
Micro Total Analysis Systems 2004, Vol 2, 2005, Netherlands. pp.357-359
Conference papers hal-00795218v1

Investigation of Human Hepatoma cell line microfluidic devices.

E. Leclerc , L. Griscom , Bruno Le Pioufle , C. Guguen-Guillouzo , A. Corlu
3rd annual International IEEE EMBS special topic conference on microtechnologies in medicine and biology., 2005, Oahu, Hawaii, United States
Conference papers hal-00019381v1

Cell Cultures over Nanoneedle Fields Euronanoforum

Matthieu Denoual , Magali Chiral , Olivier de Sagazan , Bruno Le Pioufle
Euronanoforum, Nanotechnology and the Health of EU Citizen, 2005, United Kingdom
Conference papers hal-00986470v1

Horizontal buried channels in monocrystalline silicon

Olivier de Sagazan , Matthieu Denoual , P. Guil , D. Gaudin , Bruno Le Pioufle
Conf. Proc. of DTIP of MOEMS & MEMS 2005, May 2005, Montreux, Switzerland. pp.351-354
Conference papers hal-00775898v1

Electrotransfection results on Jurkat cells on a microdevice

Magali Chiral , Matthieu Denoual , Antonin Hoël , Jimmy Aguinet , Bruno Le Pioufle
Angioskin, Electroporation based Technologies and Treatments workshop, Slovenia, 2005, 2005, Slovenia
Conference papers hal-00986477v1

Co-culture of cells in PDMS microsystem for sensitized artificial skin

L. Griscom , Y. Chateau , J. P. Pennec , Laurent Misery , Bruno Le Pioufle
2005 3rd IEEE/EMBS Special Topic Conference on Microtechnology in Medicine and Biology, 2005, China. pp.184-187, ⟨10.1109/mmb.2005.1548421⟩
Conference papers hal-00795208v1

Microsystems for dermatological research

L. Griscom , Y. Chateau , J. P. Pennec , Laurent Misery , Bruno Le Pioufle
Journal of Investigative Dermatology, 2005, Australia. pp.A20-A20
Conference papers hal-00795213v1

Behaviour of osteoblast-like cells in cellular microdevices

E. Leclerc , B. David , R. Warocquier-Clerout , L. Griscom , Bruno Le Pioufle
Micro Total Analysis Systems 2004, Vol 1, 2005, Netherlands. pp.396-398
Conference papers hal-00795188v1

Exploring the Limits of Vacuum Casting Technique for Micron and Submicron Features

Matthieu Denoual , Pascal Mognol , Bruno Le Pioufle
Proc. of Solid Freeform Symposium, 2004, United States. pp 1-9
Conference papers hal-00986465v1

Driving Liquids with Thermal Actuators

Matthieu Denoual , Olivier de Sagazan , Patrice Guil , Bruno Le Pioufle
Proc. of Actuator, 9th conference, Bremen, 2004, Germany. pp 1-9
Conference papers hal-00986466v1

Horizontal buried channels in monocrystalline silicon

Olivier de Sagazan , Matthieu Denoual , P. Guil , D. Gaudin , Bruno Le Pioufle
Proceeding of the MEMS 2004 conference, Jan 2004, Maastricht, Germany. pp.661-664
Conference papers hal-00847215v1

On-chip spermatozoa trapping by dielectrophoresis

Marie Frénéa-Robin , M. Chiral , Bruno Le Pioufle , Nathalie Melaine , Charles Pineau
8th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Sep 2004, Malmo, Sweden. pp.111-113
Conference papers hal-00412976v1

On-a-chip genotoxicity assay-application to high-throughput screening biochips

R. Piron , N. Rougier , R. Vaudry , A. Corlu , D. Glaise
Micro Total Analysis Systems 2004, Vol 1, 2004, Dordrecht, Netherlands. pp.527-529
Conference papers hal-00795175v1

A silicon micro-system for parallel gene transfection into arrayed cells

A. Tixier-Mita , J. Jun , M. Chiral , S. Ostrovidov , Marie Frénéa-Robin
8th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Sep 2004, Malmo, Sweden. pp.180-182
Conference papers hal-00412979v1

Controlling Cell Development by Microfluidic Techniques : a Step towards Whole-Cell Biosensors with Defined Biological Features

Fabrice Morin , Matthieu Denoual , Laurent Griscom , Bruno Le Pioufle , Hiroyuki Fujita
6th Micro Total Analysis System (uTAS), 2002, Japan. pp.10.1007
Conference papers hal-00986459v1

Design of biochip microelectrode arrays for cell arrangement

M. Frenea , Hervé Lhermite , Bruno Le Pioufle , H. Fujita
2nd Annual International Ieee-Embs Special Topic Conference on Microtechnologies in Medicine & Biology, Proceedings, 2002, United States. pp.140-143, ⟨10.1109/mmb.2002.1002281⟩
Conference papers hal-00795221v1

Culturing of Neurons in Microfluidic Arrays

Laurent Griscom , Patrick Degenaar , Matthieu Denoual , Fabrice Morin , Bruno Le Pioufle
2nd IEEE-EMBS Special Topic Conference on Microtechnologies in Medecine&Biology, 2002, United States. pp 160 - 163, ⟨10.1109/MMB.2002.1002305⟩
Conference papers hal-00986450v1

Arrayed Micro Needles and Electrodes for Aligned Cell Capture and Gene Insertion

Gonzalo Cabodevila , Marie Frénéa , Agnes Tixier , Katel Cozic , Bruno Le Pioufle
Chemicro, Mar 2002, Kyoto, Japan
Conference papers hal-00107155v1

Arrayed Micro Needles for Mechanical Gene Insertion

Gonzalo Cabodevila , Hiroyuki Fujita , Bruno Le Pioufle
Proceedings of SPIE -- Volume 4937 Biomedical Applications of Micro- and Nanoengineering,, Nov 2002, Melbourne, Australia. pp.90-97, ⟨10.1117/12.473962⟩
Conference papers hal-00107288v1

Soft lithographic techniques for guidance of hippocampal neurons on micro-electrode arrays

L. Griscom , P. Degenaar , Bruno Le Pioufle , E. Tamiya , H. Fujita
Transducers '01: Eurosensors Xv, Digest of Technical Papers, Vols 1 and 2, 2001, Germany. pp.338-341
Conference papers hal-00795227v1

Catching and attaching cells using an array of microholes

A. Tixier , L. Griscom , K. Cozic , H. Nagai , Bruno Le Pioufle
1st Annual International Ieee-Embs Special Topic Conference on Microtechnologies in Medicine & Biology, Proceedings, 2000, France. pp.36-40, ⟨10.1109/mmb.2000.893736⟩
Conference papers hal-00795228v1

Numerical and Analytical Modeling of the Piezoelectric Transformer and Experimental Verification

Sandrine Hallaert , Emmanuel Sarraute , Bruno Le Pioufle
Nanotech, 1999, France. pp.198-201
Conference papers hal-00794999v1