Bruno Senger

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Oligomer-based functions of mitochondrial porin

Hironori Takeda , Saori Shinoda , Chiho Goto , Akihisa Tsutsumi , Haruka Sakaue et al.

Nature Communications, 2025, 16 (1), pp.6854. ⟨10.1038/s41467-025-62021-4⟩

Article dans une revue hal-05234652v1
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A systematic bi-genomic split-GFP assay illuminates the mitochondrial matrix proteome and protein targeting routes

Yury Bykov , Solène Zuttion , Bruno Senger , Ofir Klein , Yeynit Asraf et al. Article dans une revue hal-04753356v1
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Monitoring mitochondrial localization of dual localized proteins using a Bi-Genomic Mitochondrial-Split-GFP

Solène Zuttion , Bruno Senger , Chiranjit Panja , Sylvie Friant , Róża Kucharczyk et al.

Methods in Enzymology, 2024, Methods in Enzymology, 706, pp.75-95. ⟨10.1016/bs.mie.2024.07.028⟩

Article dans une revue hal-05141285v1
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Loss of seryl-tRNA synthetase ( SARS1 ) causes complex spastic paraplegia and cellular senescence

Edgard Verdura , Bruno Senger , Miquel Raspall-Chaure , Agatha Schlüter , Nathalie Launay et al.

Journal of Medical Genetics, 2022, pp.jmedgenet-2022-108529. ⟨10.1136/jmg-2022-108529⟩

Article dans une revue hal-03798206v1
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tRNA-dependent addition of amino acids to cell wall and membrane components

Guillaume Grob , Marine Hemmerle , Nathaniel Yakobov , Nassira Mahmoudi , Frédéric Fischer et al.

Biochimie, 2022, 203, pp.93-105. ⟨10.1016/j.biochi.2022.09.017⟩

Article dans une revue (article de synthèse) hal-04235462v1
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RNA-dependent synthesis of ergosteryl-3β-O-glycine in Ascomycota expands the diversity of steryl-amino acids

Nathaniel Yakobov , Nassira Mahmoudi , Guillaume Grob , Daisuke Yokokawa , Yusuke Saga et al.

Journal of Biological Chemistry, 2022, 298 (3), pp.101657. ⟨10.1016/j.jbc.2022.101657⟩

Article dans une revue hal-03796231v1

Bi-Genomic Mitochondrial-Split-GFP − the Yeast System for Screening the Mitochondrial Matrix Echoforms of Dually Localized Proteins

Gaëtan Bader , Ludovic Enkler , Yuhei Araiso , Marine Hemmerle , Krystyna Bińko et al.

Biochimica biophysica acta (BBA) - Bioenergetics, 2022, 1863, pp.148895. ⟨10.1016/j.bbabio.2022.148895⟩

Article dans une revue hal-04833277v1
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Cex1 is a component of the COPI intracellular trafficking machinery

Ludovic Enkler , Bruno Rinaldi , J.O. de Craene , Philippe Hammann , Osamu Nureki et al.

Biology Open, 2021, 10 (3), pp.bio058528. ⟨10.1242/bio.058528⟩

Article dans une revue hal-03288818v1
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Assigning mitochondrial localization of dual localized proteins using a yeast Bi-Genomic Mitochondrial-Split-GFP

Gaétan Bader , Ludovic Enkler , Yuhei Araiso , Marine Hemmerle , Krystyna Binko et al.

eLife, 2020, 9, ⟨10.7554/eLife.56649⟩

Article dans une revue hal-02898815v1
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De Novo and Bi-allelic Pathogenic Variants in NARS1 Cause Neurodevelopmental Delay Due to Toxic Gain-of-Function and Partial Loss-of-Function Effects

Andreea Manole , Stephanie Efthymiou , Emer O'Connor , Marisa I Mendes , Matthew Jennings et al.

American Journal of Human Genetics, 2020, 107 (2), pp.311-324. ⟨10.1016/j.ajhg.2020.06.016⟩

Article dans une revue hal-02992472v1
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RNA-dependent sterol aspartylation in fungi

Nathaniel Yakobov , Frédéric Fischer , Nassira Mahmoudi , Yusuke Saga , Christopher D Grube et al.

Proceedings of the National Academy of Sciences of the United States of America, 2020, 117 (26), pp.14948-14957. ⟨10.1073/pnas.2003266117⟩

Article dans une revue pasteur-02869570v1

Cytosolic aminoacyl-tRNA synthetases: Unanticipated relocations for unexpected functions

Nathaniel Yakobov , Sylvain Debard , Frédéric Fischer , Bruno Senger , Hubert Dominique Becker

Biochimica et Biophysica Acta - Gene Regulatory Mechanisms , 2018, 1861 (4), pp.387-400. ⟨10.1016/j.bbagrm.2017.11.004⟩

Article dans une revue hal-02370188v1

Cex1 is a new component of the COPIb trans-Golgi-to-vacuole intracellular trafficking machinery

Ludovic Enkler , J.O. de Craene , Bruno Rinaldi , Philippe Hammann , Osamu Nureki et al.

BioRxiv, 2018

Article dans une revue hal-02918644v1
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Nonconventional localizations of cytosolic aminoacyl-tRNA synthetases in yeast and human cells

Sylvain Debard , Gaétan Bader , Johan-Owen de Craene , Ludovic Enkler , Séverine Bär et al.

Methods, 2017, 113, pp.91 - 104. ⟨10.1016/j.ymeth.2016.09.017⟩

Article dans une revue hal-01771885v1

Expression of Nuclear and Mitochondrial Genes Encoding ATP Synthase Is Synchronized by Disassembly of a Multisynthetase Complex

Mathieu Frechin , Ludovic Enkler , Emmanuel Tetaud , Daphné Laporte , Bruno Senger et al.

Molecular Cell, 2014, 56 (6), pp.763-776. ⟨10.1016/j.molcel.2014.10.015⟩

Article dans une revue hal-02370180v1

Exploring the evolutionary diversity and assembly modes of multi-aminoacyl-tRNA synthetase complexes: Lessons from unicellular organisms

Daphné Laporte , Jonathan Huot , Gaétan Bader , Ludovic Enkler , Bruno Senger et al.

FEBS Letters, 2014, 588 (23), pp.4268-4278. ⟨10.1016/j.febslet.2014.10.007⟩

Article dans une revue hal-02370182v1
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Crystal structure of Saccharomyces cerevisiae mitochondrial GatFAB reveals a novel subunit assembly in tRNA-dependent amidotransferases

Yuhei Araiso , Jonathan Huot , Takuya Sekiguchi , Mathieu Frechin , Frédéric Fischer et al.

Nucleic Acids Research, 2014, 42 (9), pp.6052-6063. ⟨10.1093/nar/gku234⟩

Article dans une revue hal-02370178v1
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Crystal structure of Cex1p reveals the mechanism of tRNA trafficking between nucleus and cytoplasm

Kayo Nozawa , Ryuichiro Ishitani , Tohru Yoshihisa , Mamoru Sato , Fumio Arisaka et al.

Nucleic Acids Research, 2013, 41 (6), pp.3901-3914. ⟨10.1093/nar/gkt010⟩

Article dans une revue hal-02370174v1

Arc1p: anchoring, routing, coordinating.

Mathieu Frechin , Daniel Kern , Robert Pierre Martin , Hubert Becker , Bruno Senger

FEBS Letters, 2010, 584 (2), pp.427-33. ⟨10.1016/j.febslet.2009.11.037⟩

Article dans une revue istex hal-00451322v1

Yeast mitochondrial Gln-tRNA(Gln) is generated by a GatFAB-mediated transamidation pathway involving Arc1p-controlled subcellular sorting of cytosolic GluRS.

Mathieu Fréchin , Bruno Senger , Melanie Brayé , Daniel Kern , Robert Pierre Martin et al.

Genes and Development, 2009, 23 (9), pp.1119-1130. ⟨10.1101/gad.518109⟩

Article dans une revue hal-00484960v1

Role of Arc1p in the Modulation of Yeast Glutamyl-tRNA Synthetase Activity †

Jean-Sébastien Graindorge , Bruno Senger , Denis Tritch , George Simos , Franco Fasiolo

Biochemistry, 2005, 44 (4), pp.1344-1352. ⟨10.1021/bi049024z⟩

Article dans une revue istex hal-02370163v1

Deletion of EFL1 Results in Heterogeneity of the 60S GTPase-associated rRNA Conformation

Jean-Sébastien Graindorge , Jean-Claude Rousselle , Bruno Senger , Pascal Lenormand , Abdelkader Namane et al.

Journal of Molecular Biology, 2005, 352 (2), pp.355-369. ⟨10.1016/j.jmb.2005.07.037⟩

Article dans une revue istex hal-02370162v1

Ribosome assembly in eukaryotes

Micheline Fromont-Racine , Bruno Senger , Cosmin Saveanu , Franco Fasiolo

Gene, 2003, 313, pp.17 - 42. ⟨10.1016/S0378-1119(03)00629-2⟩

Article dans une revue istex pasteur-01404699v1

Functional analysis in yeast of the Brix protein superfamily involved in the biogenesis of ribosomes

Edith Bogengruber , Peter Briza , Edith Doppler , Herbert Wimmer , Lore Koller et al.

FEMS Yeast Research, 2003, 3 (1), pp.35-43. ⟨10.1111/j.1567-1364.2003.tb00136.x⟩

Article dans une revue hal-02370150v1

The Nucle(ol)ar Tif6p and Efl1p Are Required for a Late Cytoplasmic Step of Ribosome Synthesis

Bruno Senger , Denis L.J. Lafontaine , Jean-Sebastien Graindorge , Olivier Gadal , Alain Camasses et al.

Molecular Cell, 2001, 8 (6), pp.1363-1373. ⟨10.1016/s1097-2765(01)00403-8⟩

Article dans une revue hal-02370147v1

Yeast cytoplasmic and mitochondrial methionyl-tRNA synthetases: two structural frameworks for identical functions

Bruno Senger , Laurence Despons , Philippe Walter , Hieronim Jakubowski , Franco Fasiolo

Journal of Molecular Biology, 2001, 311 (1), pp.205-216. ⟨10.1006/jmbi.2001.4844⟩

Article dans une revue istex hal-02370141v1

Mtr10p functions as a nuclear import receptor for the mRNA-binding protein Npl3p

B. Senger

EMBO Journal, 1998, 17 (8), pp.2196-2207. ⟨10.1093/emboj/17.8.2196⟩

Article dans une revue hal-02370138v1

The Modified Wobble Base Inosine in Yeast tRNA Ile Is a Positive Determinant for Aminoacylation by Isoleucyl-tRNA Synthetase †

Bruno Senger , Sylvie Auxilien , Uwe Englisch , Friedrich Cramer , Franco Fasiolo

Biochemistry, 1997, 36 (27), pp.8269-8275. ⟨10.1021/bi970206l⟩

Article dans une revue istex hal-02370118v1

Conservation in Evolution for a Small Monomeric Phenylalanyl-tRNA Synthetase of the tRNA Phe Recognition Nucleotides and Initial Aminoacylation Site †

Ruslan Aphasizhev , Bruno Senger , Jens-Uwe Rengers , Mathias Sprinzl , Philippe Walter et al.

Biochemistry, 1996, 35 (1), pp.117-123. ⟨10.1021/bi9517998⟩

Article dans une revue istex hal-02369829v1

The Presence of a D-Stem but not a T-Stem is Essential for Triggering Aminoacylation upon Anticodon Binding in Yeast Methionine tRNA

Bruno Senger , Ruslan Aphasizhev , Philippe Walter , Franco Fasiolo

Journal of Molecular Biology, 1995, 249 (1), pp.45-58. ⟨10.1006/jmbi.1995.0279⟩

Article dans une revue istex hal-02370102v1

Modulation of the Suppression Efficiency and Amino Acid Identity of an Artificial Yeast Amber Isoleucine Transfer RNA in Escherichia coli by a G-U Pair in the Anticodon Stem

V. Buttcher , B. Senger , S. Schumacher , J. Reinbolt , F. Fasiolo

Biochemical and Biophysical Research Communications, 1994, 200 (1), pp.370-377. ⟨10.1006/bbrc.1994.1458⟩

Article dans une revue istex hal-02369873v1

The anticodon triplet is not sufficient to confer methionine acceptance to a transfer RNA.

B. Senger , L. Despons , P. Walter , F. Fasiolo

Proceedings of the National Academy of Sciences of the United States of America, 1992, 89 (22), pp.10768-10771. ⟨10.1073/pnas.89.22.10768⟩

Article dans une revue hal-02369845v1

Binding of the yeast tRNAMet anticodon by the cognate methionyl-tRNA synthetase involves at least two independent peptide regions

Laurence Despons , Bruno Senger , Franco Fasiolo , Philippe Walter

Journal of Molecular Biology, 1992, 225 (3), pp.897-907. ⟨10.1016/0022-2836(92)90409-d⟩

Article dans une revue istex hal-02369843v1

Identification of potential amino acid residues supporting anticodon recognition in yeast methionyl-tRNA synthetase

Laurence Despons , Philippe Walter , Bruno Senger , Jean-Pierre Ebel , Franco Fasiolo

FEBS Letters, 1991, 289 (2), pp.217-220. ⟨10.1016/0014-5793(91)81073-h⟩

Article dans une revue hal-02369841v1