Cyril Bourgeois

35
Documents

Publications

Publications

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Monoallelic de novo variants in DDX17 cause a neurodevelopmental disorder

Eleanor Seaby , Annie Godwin , Géraldine Meyer-Dilhet , Valentine Clerc , Xavier Grand et al.
Brain - A Journal of Neurology , In press, ⟨10.1093/brain/awae320⟩
Article dans une revue hal-04943083 v1
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The AMPK-related kinase NUAK1 controls cortical axons branching by locally modulating mitochondrial metabolic functions

Marine Lanfranchi , Sozerko Yandiev , Géraldine Meyer-Dilhet , Salma Ellouze , Martijn Kerkhofs et al.
Nature Communications, 2024, 15 (1), pp.2487. ⟨10.1038/s41467-024-46146-6⟩
Article dans une revue hal-04583107 v1
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Gene-to-gene coordinated regulation of transcription and alternative splicing by 3D chromatin remodeling upon NF-κB activation

Paul Marie , Matéo Bazire , Julien Ladet , Lamya Ben Ameur , Sanjay Chahar et al.
Nucleic Acids Research, 2024, 52 (4), pp.1527-1543. ⟨10.1093/nar/gkae015⟩
Article dans une revue inserm-04830003 v1
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Helicases DDX5 and DDX17 promote heterogeneity in HBV transcription termination in infected human hepatocytes

Fleur Chapus , Guillaume Giraud , Pélagie Huchon , Mélanie Rodà , Xavier Grand et al.
Journal of Hepatology, 2024, 81 (4), pp.609-620. ⟨10.1016/j.jhep.2024.05.016⟩
Article dans une revue inserm-04830013 v1
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Modulatory role of RNA helicases in MBNL-dependent alternative splicing regulation

Katarzyna Taylor , Agnieszka Piasecka , Arkadiusz Kajdasz , Aleksandra Brzęk , Micaela Polay Espinoza et al.
Cellular and Molecular Life Sciences, 2023, 80 (11), pp.335. ⟨10.1007/s00018-023-04927-0⟩
Article dans une revue inserm-04829975 v1
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SplicingLore: a web resource for studying the regulation of cassette exons by human splicing factors

Hélène Polvèche , Jessica Valat , Nicolas Fontrodona , Audrey Lapendry , Valentine Clerc et al.
Database - The journal of Biological Databases and Curation, 2023, 2023, pp.baad091. ⟨10.1093/database/baad091⟩
Article dans une revue inserm-04829991 v1
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Myotonic dystrophy RNA toxicity alters morphology, adhesion and migration of mouse and human astrocytes

Diana Dincã , Louison Lallemant , Anchel González-Barriga , Noémie Cresto , Sandra Braz et al.
Nature Communications, 2022, 13 (1), pp.3841. ⟨10.1038/s41467-022-31594-9⟩
Article dans une revue hal-03715682 v1
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RNA helicase-dependent gene looping impacts messenger RNA processing

Sophie Terrone , Jessica Valat , Nicolas Fontrodona , Guillaume Giraud , Jean-Baptiste Claude et al.
Nucleic Acids Research, 2022, 50 (16), pp.9226-9246. ⟨10.1093/nar/gkac717⟩
Article dans une revue hal-03842696 v1
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Integrative Cell Type-Specific Multi-Omics Approaches Reveal Impaired Programs of Glial Cell Differentiation in Mouse Culture Models of DM1

Anchel González-Barriga , Louison Lallemant , Diana M Dincã , Sandra O Braz , Hélène Polvèche et al.
Frontiers in Cellular Neuroscience, 2021, 15, pp.662035. ⟨10.3389/fncel.2021.662035⟩
Article dans une revue hal-03235993 v1
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Intragenic recruitment of NF-κB drives splicing modifications upon activation by the oncogene Tax of HTLV-1

Lamya Ben Ameur , Paul Marie , Morgan Thénoz , Guillaume Giraud , Emmanuel Combe et al.
Nature Communications, 2020, 11 (1), pp.3045. ⟨10.1038/s41467-020-16853-x⟩
Article dans une revue inserm-02877333 v1

A genome‐wide screen identifies IRF2 as a key regulator of caspase‐4 in human cells

Sacha Benaoudia , Amandine Martin , Marta Puig Gamez , Gabrielle Gay , Brice Lagrange et al.
EMBO Reports, 2019, 20 (9), pp.e48235. ⟨10.15252/embr.201948235⟩
Article dans une revue inserm-04887114 v1

A genome‐wide screen identifies IRF2 as a key regulator of caspase‐4 in human cells

Sacha Benaoudia , Amandine Martin , Marta Puig Gamez , Gabrielle Gay , Brice Lagrange et al.
EMBO Reports, 2019, 20 (9), ⟨10.15252/embr.201948235⟩
Article dans une revue hal-02337614 v1
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Interplay between coding and exonic splicing regulatory sequences

Nicolas Fontrodona , Fabien Aubé , Jean-Baptiste Claude , Hélène Polvèche , Sébastien Lemaire et al.
Genome Research, 2019, 29 (5), pp.711-722. ⟨10.1101/gr.241315.118⟩
Article dans une revue inserm-04887117 v1
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Characterizing the interplay between gene nucleotide composition bias and splicing

Sébastien Lemaire , Nicolas Fontrodona , Fabien Aubé , Jean-Baptiste Claude , Hélène Polvèche et al.
Genome Biology, 2019, 20 (1), pp.259. ⟨10.1186/s13059-019-1869-y⟩
Article dans une revue inserm-04887130 v1
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Complementarity of assembly-first and mapping-first approaches for alternative splicing annotation and differential analysis from RNAseq data

Clara Benoit-Pilven , Camille Marchet , Emilie Chautard , Leandro Lima , Marie-Pierre Lambert et al.
Scientific Reports, 2018, 8 (1), ⟨10.1038/s41598-018-21770-7⟩
Article dans une revue hal-01924204 v1

The RNA helicase DDX17 controls the transcriptional activity of REST and the expression of proneural microRNAs in neuronal differentiation

Marie-Pierre Lambert , Sophie Terrone , Guillaume Giraud , Clara Benoit-Pilven , David Cluet et al.
Nucleic Acids Research, 2018, 46 (15), pp.7686-7700. ⟨10.1093/nar/gky545⟩
Article dans une revue (data paper) hal-04897064 v1

The centrosomal kinase NEK2 is a novel splicing factor kinase involved in cell survival

Chiara Naro , Federica Barbagallo , Paolo Chieffi , Cyril Bourgeois , Maria Paola Paronetto et al.
Nucleic Acids Research, 2014, 42 (5), pp.3218-3227. ⟨10.1093/nar/gkt1307⟩
Article dans une revue hal-04477050 v1
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Identification of evolutionarily conserved exons as regulated targets for the splicing activator tra2β in development.

Sushma Grellscheid , Caroline Dalgliesh , Markus Storbeck , Andrew Best , Yilei Liu et al.
PLoS Genetics, 2011, 7 (12), pp.e1002390. ⟨10.1371/journal.pgen.1002390⟩
Article dans une revue inserm-00711527 v1
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Molecular design of a splicing switch responsive to the RNA binding protein Tra2

Sushma N Grellscheid , Caroline Dalgliesh , Agata Rozanska , David Grellscheid , Cyril F Bourgeois et al.
Nucleic Acids Research, 2011, 39 (18), pp.8092-8104. ⟨10.1093/nar/gkr495⟩
Article dans une revue hal-04967870 v1

A conserved splicing mechanism of the LMNA gene controls premature aging

Isabel Cristina Lopez-Mejia , Valentin Vautrot , Marion de Toledo , Isabelle Behm-Ansmant , Cyril Bourgeois et al.
Human Molecular Genetics, 2011, 20 (23), pp.4540-4555. ⟨10.1093/hmg/ddr385⟩
Article dans une revue hal-03034380 v1
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Antagonistic factors control the unproductive splicing of SC35 terminal intron

Natacha Dreumont , Sara Hardy , Isabelle Behm-Ansmant , Liliane Kister , Christiane Branlant et al.
Nucleic Acids Research, 2010, 38 (4), pp.1353 - 1366. ⟨10.1093/nar/gkp1086⟩
Article dans une revue hal-01738427 v1

Role of RNA structure and protein factors in the control of HIV-1 splicing

Jean-Michel Saliou , Cyril Bourgeois , L. Ayadi-Ben Mena , Delphine Ropers , S. Jacquenet et al.
Frontiers in Bioscience-Landmark, 2009, 14, pp.2714-2729
Article dans une revue hal-00793011 v1
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Proteomic identification of heterogeneous nuclear ribonucleoprotein L as a novel component of SLM/Sam68 Nuclear Bodies.

Prabhakar Rajan , Caroline Dalgliesh , Cyril F Bourgeois , Monika Heiner , Kaveh Emami et al.
BMC Cell Biology, 2009, 10 (1), pp.82. ⟨10.1186/1471-2121-10-82⟩
Article dans une revue inserm-00624805 v1

Alternative RNA splicing complexes containing the scaffold attachment factor SAFB2.

Kate A Sergeant , Cyril F Bourgeois , Caroline Dalgliesh , Julian P Venables , James Stevenin et al.
Journal of Cell Science, 2007, 120 (Pt 2), pp.309-19. ⟨10.1242/jcs.03344⟩
Article dans une revue hal-00166256 v1

Up-regulation of the ubiquitous alternative splicing factor Tra2beta causes inclusion of a germ cell-specific exon.

Julian P Venables , Cyril F Bourgeois , Caroline Dalgliesh , Liliane Kister , James Stevenin et al.
Human Molecular Genetics, 2005, 14 (16), pp.2289-303. ⟨10.1093/hmg/ddi233⟩
Article dans une revue istex hal-00187820 v1

Toxic CUG RNA repeats disrupt developmentally-regulated splicing in oligodendrocytes causing transient hypomyelination in a mouse model of myotonic dystrophy.

Louison Lallemant , Sandra Braz , Anchel González-Barriga , Paul Magneron , Aurélien Cordier et al.
The European Meeting on Glial Cells in Health and Disease, Jul 2023, Berlin, France
Poster de conférence hal-04005524 v1

Myotonic dystrophy RNA toxicity alters morphology, adhesion and migration of mouse and human astrocytes

Diana Mihaela Dincã , Louison Lallemant , Anchel González-Barriga , Noemie Cresto , Sandra Braz et al.
International Myotonic Dystrophy Consortium Meeting, Jun 2022, Osaka, Japan
Poster de conférence hal-04006873 v1

RNA toxicity in myotonic dystrophy causes pronounced spliceopathy in astrocytes, in association with defective cell adhesion and morphology, erratic migration and impaired polarization

Diana Mihaela Dincã , Anchel González-Barriga , Sandra Braz , Laure-Elise Pillet , Noémie Cresto et al.
Cold Spring Harbor Laboratory Meeting on Glia in Health and Disease, Jul 2020, Cold Spring Harbor (New York), United States
Poster de conférence hal-04009836 v1

Toxic RNA affects astrocyte adhesion, spreading and migration in myotonic dystrophy, and impacts neuritogenesis through abnormal glial-neuronal interactions

Diana Mihaela Dincã , Anchel González-Barriga , Sandra Braz , Cyril F Bourgeois , Géraldine Sicot et al.
The European Meeting on Glial Cells in Health and Disease, Jul 2019, Porto, Portugal
Poster de conférence hal-04009975 v1

Investigating oligodendrocyte dysfunction in DM1 brain disease

Sandra Braz , Raphael Blain , Cyril F Bourgeois , Aline Huguet-Lachon , Alain Schmitt et al.
The European Meeting on Glial Cells in Health and Disease, Jul 2019, Porto, Portugal
Poster de conférence hal-04010005 v1

Combination of Omics Approaches to Study Molecular Abnormalities in Individual Brain Cell Types of a DM1 Mouse Model

Anchel González-Barriga , Diana Mihaela Dincã , Sandra Braz , Aurélien Cordier , Cerina Chhuon et al.
International Myotonic Dystrophy Consortium Meeting (IDMC-12), Jun 2019, Gothenburg, Sweden.
Poster de conférence hal-04009963 v1