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Cédric Przybylski

Ingénieur de recherche HDR, CNRS détaché au LAMBE, Univ. Evry Paris-Saclay
58
Documents
Affiliations actuelles
Identifiants chercheurs

Présentation

Biochimiste de formation, j’ai obtenu en 2006 un diplôme d’ingénieur spécialisé en chimie analytique au CNAM. J’ai ensuite exercé mes activités comme ingénieur d’études en techniques d’analyse des biomolécules au sein du LAMBE (Université d’Evry Val-d’Essonne) jusqu’en 2015, période au cours de laquelle j’ai obtenu mon doctorat en chimie analytique (2014). En 2016, j’ai été nommé ingénieur de recherche en analyse chimique au CNRS et affecté à l’IPCM (Sorbonne Université). Depuis 2023, je suis détaché au sein du LAMBE (Univ. Evry paris-Saclay). Mes activités de recherche ont pour objectifs de développer des outils analytiques innovants, basés sur la spectrométrie de masse, et appliqués aux domaines de la glycomique et de la chimie supra-/macromoléculaire. Ils incluent en autres l’analyse et l’élucidation structurale d’oligo-/polysaccharides complexes, notamment polyanioniques ou polycationiques, la caractérisation d’assemblages supra- et macromoléculaires et l’étude de complexes non covalents impliquant des biomolécules et/ou des métaux.

Publications

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Ion mobility mass spectrometry enables the discrimination of positional isomers and the detection of conformers from cyclic oligosaccharides-metals supramolecular complexes

Véronique Bonnet , Gilles Clodic , Christian Sonnendecker , Wolfgang Zimmermann , Cédric Przybylski
Carbohydrate Polymers, 2023, 320, pp.121205. ⟨10.1016/j.carbpol.2023.121205⟩
Article dans une revue hal-04188988v1
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Structure and functional impact of glycosaminoglycan modification of HSulf-2 endosulfatase revealed by atomic force microscopy and mass spectrometry

Ilham Seffouh , Mélanie Bilong , Cédric Przybylski , Nesrine El Omrani , Salomé Poyer
Scientific Reports, 2023, 13 (1), ⟨10.1038/s41598-023-49147-5⟩
Article dans une revue hal-04348199v1
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Probing topology of supramolecular complexes between cyclodextrins and alkali metals by ion mobility-mass spectrometry

Cédric Przybylski , Véronique Bonnet
Carbohydrate Polymers, 2022, ⟨10.1016/j.carbpol.2022.120019⟩
Article dans une revue hal-03931502v1
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Potential energetic return on investment positively correlated with overall soil microbial activity

Louis Dufour , Anke M Herrmann , Julie Leloup , Cédric Przybylski , Ludovic Foti
Soil Biology and Biochemistry, 2022, 173, pp.108800. ⟨10.1016/j.soilbio.2022.108800⟩
Article dans une revue hal-03775651v1

Enhanced Gene Delivery Triggered by Dual pH/Redox Responsive Host‐Guest Dimerization of Cyclooligosaccharide Star Polycations

Ana Carbajo-Gordillo , José López-Fernández , Juan Benito , José Jiménez Blanco , María Santana-Armas
Macromolecular Rapid Communications, 2022, 43 (11), pp.2200145. ⟨10.1002/marc.202200145⟩
Article dans une revue hal-04049810v1

The formulation of a CMC binder/silicon composite anode for Li-ion batteries: from molecular effects of ball milling on polymer chains to consequences on electrochemical performances

Mariama Ndour , Jean-Pierre Bonnet , Sébastien Cavalaglio , Tristan Lombard , Matthieu Courty
Materials Advances, 2022, 3 (23), pp.8522-8533. ⟨10.1039/D2MA00702A⟩
Article dans une revue hal-03968700v1
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Discrimination of isomeric trisaccharides and their relative quantification in honeys using trapped ion mobility spectrometry

Cédric Przybylski , Véronique Bonnet
Food Chemistry, 2021, 341, pp.128182. ⟨10.1016/j.foodchem.2020.128182⟩
Article dans une revue hal-03146652v1
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Trifaceted Mickey Mouse Amphiphiles for Programmable Self‐Assembly, DNA Complexation and Organ‐Selective Gene Delivery

Ana Carbajo-Gordillo , Manuel González-Cuesta , José L Jiménez Blanco , Juan M Benito , María Santana-Armas
Chemistry - A European Journal, 2021, 27 (36), pp.9429 - 9438. ⟨10.1002/chem.202100832⟩
Article dans une revue hal-03275987v1
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Cytotoxic BODIPY-Appended Half-Sandwich Iridium(III) Complex Forms Protein Adducts and Induces ER Stress

Robin Ramos , Jean-François Gilles , Romain Morichon , Cédric Przybylski , Benoît Caron
Journal of Medicinal Chemistry, 2021, 64 (22), pp.16675-16686. ⟨10.1021/acs.jmedchem.1c01335⟩
Article dans une revue hal-03498836v1
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Programmed synthesis of Hepta-differentiated b-Cyclodextrin: 1 out of 117655 arrangements

Jiang Liu , Bo Wang , Cédric Przybylski , Olivia Bistri-Aslanoff , Mickaël Ménand
Angewandte Chemie International Edition, 2021, ⟨10.1002/anie.202102182⟩
Article dans une revue hal-03158175v1
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Experimental and computational diagnosis of the fluxional nature of a benzene-1,3,5-tricarboxamide-based hydrogen-bonded dimer

Matthieu Raynal , Yan Li , Claire Troufflard , Cédric Przybylski , Geoffrey Gontard
Physical Chemistry Chemical Physics, 2021, ⟨10.1039/D0CP06128J⟩
Article dans une revue hal-03142819v1
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Cyclodextrin Complexation Studies as the First Step for Repurposing of Chlorpromazine

Zhiqiang Wang , David Landy , Christina Sizun , Christine Cézard , Audrey Solgadi
International Journal of Pharmaceutics, 2020, 584, pp.119391. ⟨10.1016/j.ijpharm.2020.119391⟩
Article dans une revue hal-02885940v1
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Investigation of Action Pattern of a Novel Chondroitin Sulfate/Dermatan Sulfate 4- O -Endosulfatase

Wenshuang Wang , Cédric Przybylski , Xiaojuan Cai , Chrystel Lopin-Bon , Runmiao Jiao
Biochemical Journal, 2020, 478 (2), pp.281-298. ⟨10.1042/BCJ20200657⟩
Article dans une revue hal-03098070v1
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Catalysis and specificity of the polycondensation of aminopropyltrimethoxysilane on nucleic acids

Nathalie Jarroux , Marie-Jeanne Clément , Cédric Przybylski , Olek Maciejak , Patrick A. Curmi
GSC Biological and Pharmaceutical Sciences, 2020, 13 (2), pp.290-299. ⟨10.30574/gscbps.2020.13.2.0332⟩
Article dans une revue hal-03702917v1
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First step to the improvement of the blood brain barrier passage of atazanavir encapsulated in sustainable bioorganic vesicles

Florian Nolay , Emmanuel Sevin , Mathieu Létévé , Abed Bil , Fabien Gosselet
International Journal of Pharmaceutics, 2020, 587, pp.119604. ⟨10.1016/j.ijpharm.2020.119604⟩
Article dans une revue hal-02980826v1
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Interactions of Calcium with Chlorogenic and Rosmarinic Acids: An Experimental and Theoretical Approach

Estelle Palierse , Cédric Przybylski , Dalil Brouri , Claude Jolivalt , Thibaud Coradin
International Journal of Molecular Sciences, 2020, 21 (14), pp.4948. ⟨10.3390/ijms21144948⟩
Article dans une revue hal-02924443v1
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Surface plasmon resonance imaging coupled to on-chip mass spectrometry: a new tool to probe protein-GAG interactions

Cédric Przybylski , Florence Gonnet , Els Saesen , Hugues Lortat-Jacob , Régis Daniel
Analytical and Bioanalytical Chemistry, 2020, ⟨10.1007/s00216-019-02267-2⟩
Article dans une revue hal-02401458v1

Harnessing Polyisobutylene by Rotaxanation with γ-Cyclodextrin: Opportunities for Making Smart Molecular Necklaces

Cédric Przybylski , Hassen Ramoul , Véronique Bonnet , Mathilde Abad , Nathalie Jarroux
Macromolecular Chemistry and Physics, 2019, 220 (5), pp.1800502. ⟨10.1002/MACP.201800502⟩
Article dans une revue hal-02104555v1

Large-Ring Cyclodextrins as Chiral Selectors for Enantiomeric Pharmaceuticals

Christian Sonnendecker , Sebastian Thürmann , Cédric Przybylski , Franziska D. Zitzmann , Nicole Heinke
Angewandte Chemie International Edition, 2019, ⟨10.1002/ange.201900911⟩
Article dans une revue hal-02885937v1

The Uncommon Strong Inhibition of α-Glucosidase by Multivalent Glycoclusters Based on Cyclodextrin Scaffolds

Urjwan Alali , Aurélie Vallin , Abed Bil , Takwa Khanchouche , David Mathiron
Organic & Biomolecular Chemistry, 2019, 17 (30), pp.7228--7237. ⟨10.1039/C9OB01344J⟩
Article dans une revue hal-02885917v1
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Dynamic Control of the Self-Assembling Properties of Cyclodextrins by the Interplay of Aromatic and Host-Guest Interactions

Tania Neva , Thais Carmona , Juan M Benito , Cédric Przybylski , Carmen Ortiz Mellet
Frontiers in Chemistry, 2019, 7, ⟨10.3389/fchem.2019.00072⟩
Article dans une revue hal-02344581v1
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Mass spectrometry analysis of the human endosulfatase Hsulf-2

Ilham Seffouh , Cédric Przybylski , Amal Seffouh , Rana El Masri , Romain R Vivès
Biochemistry and Biophysics Reports, 2019, 18, pp.100617. ⟨10.1016/j.bbrep.2019.01.010⟩
Article dans une revue hal-02043614v1

A microscale double labelling of GAG oligosaccharides compatible with enzymatic treatment and mass spectrometry

Cédric Przybylski , Véronique Bonnet , Romain R Vivès
Chemical Communications, 2019, 55, pp.4182-4185. ⟨10.1039/C9CC00254E⟩
Article dans une revue hal-02081502v1
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Photosensitized oxidative addition to gold(i) enables alkynylative cyclization of o-alkylnylphenols with iodoalkynes

Zhonghua Xia , Vincent Corcé , Fen Zhao , Cédric Przybylski , Agathe Espagne
Nature Chemistry, 2019, 11 (9), pp.797-805. ⟨10.1038/s41557-019-0295-9⟩
Article dans une revue hal-02282216v1

Biomimetic ion channels formation by emulsion based on chemically modified cyclodextrin nanotubes

Laurent Bacri , Hajar Mamad-Hemouch , Cédric Przybylski , Bénédicte Thiebot , Gilles Patriarche
Faraday Discussions, 2018, 210, pp.41-54. ⟨10.1039/C8FD00030A⟩
Article dans une revue hal-02006444v1
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Embedding a Ruthenium-Based Structural Mimic of the [Fe]-Hydrogenase Cofactor into Papain

Chandan Kr Barik , Rakesh Ganguly , Yongxin Li , Cédric Przybylski , Michèle Salmain
Inorganic Chemistry, 2018, 57 (19), pp.12206-12212. ⟨10.1021/acs.inorgchem.8b01835⟩
Article dans une revue hal-01969442v1

Revealing Cooperative Binding of Polycationic Cyclodextrins with DNA Oligomers by Capillary Electrophoresis Coupled to Mass Spectrometry

Cédric Przybylski , Juan M. Benito , Véronique Bonnet , Carmen Ortiz Mellet , José M. Garcìa Fernández
Analytica Chimica Acta, 2018, 1002, pp.70--81. ⟨10.1016/j.aca.2017.11.034⟩
Article dans une revue hal-02885934v1
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Versatile cyclodextrin nanotube synthesis with functional anchors for efficient ion channel formation: design, characterization and ion conductance

Hajar Mamad-Hemouch , Laurent Bacri , Cécile Huin , Cédric Przybylski , Bénédicte Thiebot
Nanoscale, 2018, 10 (32), pp.15303-15316. ⟨10.1039/C8NR02623H⟩
Article dans une revue hal-01955731v1
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Cyclodextrin-assisted low-metal Ni-Pd/Al2O3 bimetallic catalysts for the direct amination of aliphatic alcohols

Ajay Tomer , Bright Kusema , Jean-François Paul , Cédric Przybylski , Eric Monflier
Journal of Catalysis, 2018, 368, pp.172 - 189. ⟨10.1016/j.jcat.2018.10.002⟩
Article dans une revue hal-01901874v1

Xylylene Clips for the Topology-Guided Control of the Inclusion and Self-Assembling Properties of Cyclodextrins

Tania Neva , Thais Carmona , Juan M. Benito , Cédric Przybylski , Carmen Ortiz Mellet
Journal of Organic Chemistry, 2018, 83 (10), pp.5588--5597. ⟨10.1021/acs.joc.8b00602⟩
Article dans une revue hal-02885933v1

Proteins as Macromolecular Ligands for Metal-Catalysed Asymmetric Transfer Hydrogenation of Ketones in Aqueous Medium

José de Jesús Cázares-Marinero , Cédric Przybylski , Michèle Salmain
European Journal of Inorganic Chemistry, 2018, 2018 (12), pp.1383 - 1393. ⟨10.1002/ejic.201701359⟩
Article dans une revue hal-01878655v1

Interactions between shape‐persistent macromolecules as probed by AFM

Johanna Blass , Jessica Brunke , Franziska Emmerich , Cédric Przybylski , Vasil M Garamus
Beilstein Journal of Organic Chemistry, 2017, 13, pp.938--951. ⟨10.3762/bjoc.13.95⟩
Article dans une revue hal-01665226v1

Facile preparation of Ni/Al 2 O 3  catalytic formulations with the aid of cyclodextrin complexes: Towards highly active and robust catalysts for the direct amination of alcohols

Ajay Tomer , Frédéric Wyrwalski , Cédric Przybylski , Jean-François Paul , Eric Monflier
Journal of Catalysis, 2017, 356, pp.111-124. ⟨10.1016/j.jcat.2017.10.006⟩
Article dans une revue hal-01688064v1

Efficient recovery of glycosaminoglycan oligosaccharides from polyacrylamide gel electrophoresis combined with mass spectrometry analysis

Pierre-Edouard Bodet , Isabelle Salard , Cédric Przybylski , Florence Gonnet , Cathy Gomila
Analytical and Bioanalytical Chemistry, 2017, 409 (5), pp.1257-1269. ⟨10.1007/s00216-016-0052-5⟩
Article dans une revue hal-01966743v1

Deciphering of polycationic carbohydrate based non‐viral gene delivery agents by ESI‐LTQ‐Orbitrap using CID/HCD pairwise tandem mass spectrometry

Cédric Przybylski , Juan M. Benito , Véronique Bonnet , Carmen Ortiz Mellet , José M. García Fernández
RSC Advances, 2016, 6 (82), pp.78803-78817. ⟨10.1039/C6RA14508F⟩
Article dans une revue hal-01665230v1

Toward a suitable structural analysis of gene delivery carrier based on polycationic carbohydrates by electron transfer dissociation tandem mass spectrometry

Cédric Przybylski , Juan M. Benito , Véronique Bonnet , Carmen Ortiz Mellet , José M. García Fernández
Analytica Chimica Acta, 2016, 948, pp.62--72. ⟨10.1016/j.aca.2016.11.001⟩
Article dans une revue hal-01665229v1

Cyclodextrin‐cobalt (II) molecule‐ion pairs as precursors to active Co3O4/ZrO2 catalysts for the complete oxidation of formaldehyde: Influence of the cobalt source

Lei Bai , Frédéric Wyrwalski , Maryam Safariamin , Rudina Bleta , Jean‐françois Lamonier
Journal of Catalysis, 2016, 341, pp.191-204. ⟨10.1016/j.jcat.2016.07.006⟩
Article dans une revue hal-01665231v1

Radical Coupling Allows a Fast and Tuned Synthesis of Densely Packed Polyrotaxanes Involving γ-Cyclodextrins and Polydimethylsiloxane

François Blin , Cédric Przybylski , Véronique Bonnet , Marie-Jeanne Clément , Patrick. A. Curmi
Macromolecules, 2016, 49 (9), pp.3232-3243. ⟨10.1021/acs.macromol.6b00492⟩
Article dans une revue hal-02065253v1

On-line capillary isoelectric focusing hyphenated to native electrospray ionization mass spectrometry for the characterization of interferon-γ and variants

Cédric Przybylski , Meriem Mokaddem , Mehdi Prull-Janssen , Els Saesen , Hugues Lortat-Jacob
Analyst, 2015, 140 (2), pp.543-550. ⟨10.1039/c4an01305k⟩
Article dans une revue hal-01096701v1

Biomimetic Nanotubes Based on Cyclodextrins for Ion-Channel Applications

Hajar Mamad-Hemouch , Hassen Ramoul , Mohammad Abou Taha , Laurent Bacri , Cécile Huin
Nano Letters, 2015, 15 (11), pp.7748-7754. ⟨10.1021/acs.nanolett.5b03938⟩
Article dans une revue hal-02006482v1

Probing the common alkali metal affinity of native and variously methylated β-cyclodextrins by combining electrospray-tandem mass spectrometry and molecular modeling

Cédric Przybylski , Véronique Bonnet , Christine Cézard
Physical Chemistry Chemical Physics, 2015, 17 (29), pp.19288-19305. ⟨10.1039/c5cp02895g⟩
Article dans une revue hal-02065095v1

MALDI-TOF MS and ESI-LTQ-Orbitrap tandem mass spectrometry reveal specific porphyranase activity from a Pseudoalteromonas atlantica bacterial extract

C. Przybylski , G. Correc , M. Fer , F. Gonnet , W. Helbert
RSC Advances, 2015, 5 (98), pp.80793-80803. ⟨10.1039/C5RA14449C⟩
Article dans une revue hal-01966791v1

Capillary electrophoresis fingerprinting of 8-aminopyrene-1,3,6-trisulfonate derivatized nitrocellulose after partial acid depolymerization

Elodie Alinat , Nathalie Delaunay , Cédric Przybylski , Régis Daniel , Xavier Archer
Journal of Chromatography A, 2015, 1387, pp.134-143. ⟨10.1016/j.chroma.2015.01.092⟩
Article dans une revue hal-01966794v1

Identification of Novel PAMP-Triggered Phosphorylation and Dephosphorylation Events in Arabidopsis thaliana by Quantitative Phosphoproteomic Analysis

Naganand Rayapuram , Ludovic Bonhomme , Jean Bigeard , Kahina Haddadou , Cédric Przybylski
Journal of Proteome Research, 2014, 13 (4), pp.2137-2151. ⟨10.1021/pr401268v⟩
Article dans une revue hal-02112300v1

Derivatization strategies for CE-LIF analysis of biomarkers: Toward a clinical diagnostic of familial transthyretin amyloidosis

Sonia Korchane , Antoine Pallandre , Cédric Przybylski , Antoine Poüs , Florence Gonnet
Electrophoresis, 2014, 35 (7), pp.1050-1059. ⟨10.1002/elps.201300426⟩
Article dans une revue hal-01966802v1

HSulf sulfatases catalyze processive and oriented 6-O-desulfation of heparan sulfate that differentially regulates fibroblast growth factor activity

Amal Seffouh , Fabian Milz , Cédric Przybylski , Cédric Laguri , Arie Oosterhof
FASEB Journal, 2013, 27 (6), pp.2431-2439. ⟨10.1096/fj.12-226373⟩
Article dans une revue hal-00871189v1

Capillary zone electrophoresis and capillary electrophoresis-mass spectrometry for analyzing qualitative and quantitative variations in therapeutic albumin

Anne-Lise Marie , Cédric Przybylski , Florence Gonnet , Régis Daniel , Remi Urbain
Analytica Chimica Acta, 2013, 800, pp.103-110. ⟨10.1016/j.aca.2013.09.023⟩
Article dans une revue hal-01967529v1

Discrimination of cyclic and linear oligosaccharides by tandem mass spectrometry using collision-induced dissociation (CID), pulsed-Q-dissociation (PQD) and the higher-energy C-trap dissociation modes: Study of cyclic and linear oligosaccharides by MS/MS

Cédric Przybylski , Véronique Bonnet
Rapid Communications in Mass Spectrometry, 2013, 27 (1), pp.75-87. ⟨10.1002/RCM.6422⟩
Article dans une revue hal-02112600v1

Critical parameters for the analysis of anionic oligosaccharides by desorption electrospray ionization mass spectrometry

Cédric Przybylski , Florence Gonnet , William Buchmann , Régis Daniel
Journal of Mass Spectrometry, 2012, 47 (8), pp.1047-1058. ⟨10.1002/jms.3052⟩
Article dans une revue hal-01967547v1

Single Molecule Detection of Glycosaminoglycan Hyaluronic Acid Oligosaccharides and Depolymerization Enzyme Activity Using a Protein Nanopore

Aziz Fennouri , Cédric Przybylski , Manuela Pastoriza-Gallego , Laurent Bacri , Loïc Auvray
ACS Nano, 2012, 6 (11), pp.9672-9678. ⟨10.1021/nn3031047⟩
Article dans une revue hal-01967543v1

Performance evaluation on a wide set of matrix-assisted laser desorption ionization matrices for the detection of oligosaccharides in a high-throughput mass spectrometric screening of carbohydrate depolymerizing enzymes

David Ropartz , Pierre-Edouard Bodet , Cédric Przybylski , Florence Gonnet , Régis Daniel
Rapid Communications in Mass Spectrometry, 2011, 25 (14), pp.2059-2070. ⟨10.1002/rcm.5060⟩
Article dans une revue hal-01967556v1

HABA-based ionic liquid matrices for UV-MALDI-MS analysis of heparin and heparan sulfate oligosaccharides.

Cedric Przybylski , Florence Gonnet , David Bonnaffé , Yael Hersant , Hugues Lortat-Jacob
Glycobiology, 2010, 20 (2), pp.224-234. ⟨10.1093/glycob/cwp169⟩
Article dans une revue hal-01063049v1

Desorption Electrospray Ionization Mass Spectrometry of Glycosaminoglycans and Their Protein Noncovalent Complex

C. Przybylski , F. Gonnet , Y. Hersant , D. Bonnaffé , Hugues Lortat-Jacob
Analytical Chemistry, 2010, 82 (22), pp.9225-9233. ⟨10.1021/ac1016198⟩
Article dans une revue hal-01967559v1

Analysis of Human C1q by Combined Bottom-up and Top-down Mass Spectrometry

Delphine Pflieger , Cédric Przybylski , Florence Gonnet , Jean-Pierre Le Caer , Thomas Lunardi
Molecular and Cellular Proteomics, 2010, 9 (4), pp.593-610. ⟨10.1074/mcp.M900350-MCP200⟩
Article dans une revue hal-01967565v1