Cédric Raoul

56%
Libre accès
66
Documents
Affiliations actuelles
  • Institut des Neurosciences de Montpellier (INM)
  • CMCS-EPFL (CMCS-EPFL)
  • Hôpital Gui de Chauliac [CHU Montpellier]
Identifiants chercheurs

Présentation


Publications

Publications

Multi-scale microscopic Characterization of Skeletal Muscle Fibers in an ALS Mouse Model SOD1-G93A

Imane Belkasmi , Richard Younes , Marta Martin Fernandez , Joshua de Lizaraga , Thierry Cloitre et al.
2nd International Conference on BioMedical Photonics 2025, Apr 2025, Palavas Les Flots, France
Poster de conférence hal-05025415 v1

Changes induced by amyotrophic lateral sclerosis in the morphology and nanomechanics of skeletal muscle fibers.

Marta Martin Fernandez , Richard Younes , Imane Belkasmi , Joshua de Lizaraga , Thierry Cloitre et al.
2nd International Conference on BioMedical Photonics, Apr 2025, Palavas Les Flots, France
Communication dans un congrès hal-05027188 v1

Deciphering Novel Glial Differential Markers in Amyotrophic Lateral Sclerosis

Sara Marmolejo-Martínez-Artesero , Désiré Challuau , Frédérique Scamps , Cédric Raoul
FENS forum 2024, Jun 2024, Vienna, Austria
Communication dans un congrès hal-04916355 v1

IDENTIFICATION OF SPECIFIC MOLECULAR MARKERS OF ALS VULNERABLE MOTONEURONS

Youssef Issa , Sara Marmolejo-Martínez-Artesero , Cédric Raoul , Cécile Hilaire , Frédérique Scamps
Meeting of the International Motoneuron Society, Jun 2024, Bordeaux, France
Communication dans un congrès hal-04916029 v1

Unconventional secretion of misfolded SOD1 in ALS: a novel mechanism of toxicity spreading

Philippe Gosset , Véronique Brugioti , Eloïse Néel , Marlysa Labatut , Désiré Challuau et al.
10ème journée de la recherche sur la SLA et maladies du neurone moteur, Oct 2024, Paris, France
Communication dans un congrès hal-04916343 v1

Identification of specific molecular markers of ALS vulnerable motoneurons

Youssef Issa , Sara Marmolejo-Martínez-Artesero , Cédric Raoul , Frédérique Scamps , Cécile Hilaire
33rd Ion Channels Meeting, Sète from 8th to 11th September 2024, Sep 2024, Sète, France
Communication dans un congrès hal-04923443 v1

Diverse mechanisms of spinal motoneuron death during development and pathology

Cédric Raoul
Meeting of the International Motoneuron Society, Jun 2024, Bordeaux, France
Communication dans un congrès hal-04916007 v1

Contribution of neutrophils extracellular DNA traps to Amyotrophic Lateral Sclerosis pathogenesis

Caroline Ritacco , Véronique Brugioti , Désiré Challuau , Elisa de la Cruz , Florence Esselin et al.
10ème journée de la recherche sur la SLA et maladies du neurone moteur, Oct 2024, Paris, France
Communication dans un congrès hal-04916322 v1

Extrinsic mechanisms of motoneuron vulnerability in ALS

Cédric Raoul
International meeting, ALS: beyond the motoneuron, Nov 2023, Montevideo, Uruguay
Communication dans un congrès hal-04916037 v1

UNDERSTANDING THE TOXICITY OF ALS-ASSOCIATED KIF5A MUTANT TO MOTONEURONS

Sophie Layalle , Franck Aimond , Cristina López-Andrés , Véronique Brugioti , Victoria Gizzi et al.
8ème journée de la recherche sur la SLA et maladies du neurone moteur, Oct 2022, Paris, France
Communication dans un congrès hal-04916273 v1

LE POISSON-ZÈBRE : UNE AIDE RAPIDE À L’INTERPRÉTATION DES VARIANTS RARES DANS LA SLA

Arthur Forget , Aleksandra Chudinova , Mireille Rossel , Nicolas Pageot , Audrey Gabelle-Deloustal et al.
8ème journée de la recherche sur la SLA et maladies du neurone moteur, Oct 2022, Paris, France
Communication dans un congrès hal-04916241 v1

UNCONVENTIONAL SECRETION OF TDP-43, A PATHOGENIC DETERMINANT OF AMYOTROPHIC LATERAL SCLEROSIS

Flavien Picard , E Errazurz-Cerda , Emilien Bernard , Cédric Raoul , Alexandre Mezghrani et al.
8ème journée de la recherche sur la SLA et maladies du neurone moteur, Oct 2022, Paris, France
Communication dans un congrès hal-04916299 v1

ALS: basic mechanisms revisited

Cédric Raoul
Pathogenesis of Neurodegenerative Diseases, Apr 2021, Braga, Portugal
Communication dans un congrès hal-04916049 v1

UNCONVENTIONAL SECRETION OF MISFOLDED SOD1 IN ALS: A NOVEL MECHANISM OF TOXICITY SPREADING

Philippe Gosset , Désiré Challuau , Frédérique Scamps , Cédric Raoul , Alexandre Mezghrani
7ème journée de la recherche sur la SLA et maladies du neurone moteur, Oct 2021, Paris, France
Communication dans un congrès hal-04916218 v1

Extrinsic and intrinsic mechanisms of motoneuron vulnerability in ALS

Cédric Raoul
Brain and Mind symposium, Oct 2020, Helsinki, Finland
Communication dans un congrès hal-04916073 v1

ZEBRAFISH MODEL AS A FUNCTIONAL TOOL TO ANALYSE PATHOGENICITY OF SOD1 GENE VARIANTS

Aleksandra Chudinova , Mireille Rossel , Emilien Bernard , Gwendal Le Masson , William Camu et al.
6ème journée de la recherche sur la SLA et maladies du neurone moteur, Oct 2020, Paris, France
Communication dans un congrès hal-04916206 v1

PREMATURE TERMINATION CODONS IN SOD1 CAUSING ALS ARE PREDICTED TO ESCAPE THE NONSENSE-MEDIATED MRNA DECAY

Claire Guissart , Kevin Mouzat , Jovana Kantar , Anne Polge , Cédric Raoul et al.
6ème journée de la recherche sur la SLA et maladies du neurone moteur, Oct 2020, Paris, France
Communication dans un congrès hal-04916192 v1

Extrinsic and intrinsic mechanisms of motoneuron vulnerability in ALS

Cédric Raoul
Institute for Stroke and Dementia Research, May 2019, Munich, Germany
Communication dans un congrès hal-04916089 v1

Self-reactive CD8+ T lymphocytes expressing ALS-causing SOD1 mutant trigger death of motoneurons

Cédric Raoul
French, German and Swiss meeting on ALS/FTD, Feb 2019, Günzburg-Ulm, Germany
Communication dans un congrès hal-04916099 v1

RECONNAISSANCE SELECTIVE DE CELLULES EN DEGENERESCENCE & DE PROTEINES AGREGEES PAR PROPERDINE POUR CONTRER L'INFLAMMATION DANS LA SLA

Roxane Crabé , Céline Salsac , Antoine Picot , Désiré Challuau , Frédérique Scamps et al.
5ème journée de la recherche sur la SLA et maladies du neurone moteur, Oct 2019, Paris, France
Communication dans un congrès hal-04916179 v1

Basics mechanisms of ALS

Cédric Raoul
Pathogenesis of Neurodegenerative Diseases: finding a common ground – 3rd edition, Apr 2019, Braga, Portugal
Communication dans un congrès hal-04916060 v1

Contribution of NCR1 & Properdin to ALS pathogenesis

Roxane Crabé , Cédric Raoul
French, German and Swiss meeting on amyotrophic lateral sclerosis and fronto-temporal dementia, Feb 2019, Günzburg-Ulm, Germany
Communication dans un congrès hal-04916383 v1

Nanomechanical aspects of brain metastasis formation and amyotrophic lateral sclerosis

Bela Varga , Emmanuelle Coque , Marta Martin , Cécile Hilaire , Ana Sánchez-Vicente et al.
Asylum Research AFM workshop, Sep 2018, Grenoble, France
Communication dans un congrès hal-01899130 v1
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A Novel De Novo Missense Mutation in KIF1A Associated with Young-Onset Upper-Limb Amyotrophic Lateral Sclerosis

Emilien Bernard , Florent Cluse , Adrien Bohic , Marc Hermier , Cédric Raoul et al.
International Journal of Molecular Sciences, 2024, 25 (15), pp.8170. ⟨10.3390/ijms25158170⟩
Article dans une revue hal-04767138 v1
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The ALS-associated KIF5A P986L variant is not pathogenic for Drosophila motoneurons

Sophie Layalle , Franck Aimond , Véronique Brugioti , Claire Guissart , Cédric Raoul et al.
Scientific Reports, 2024, 14 (1), pp.19540. ⟨10.1038/s41598-024-70543-y⟩
Article dans une revue hal-04767128 v1
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TNFα prevents FGF4-mediated rescue of astrocyte dysfunction and reactivity in human ALS models

Erika Velasquez , Ekaterina Savchenko , Sara Marmolejo-Martínez-Artesero , Désiré Challuau , Aline Aebi et al.
Neurobiology of Disease, 2024, 201, pp.106687. ⟨10.1016/j.nbd.2024.106687⟩
Article dans une revue hal-04767141 v1
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Pharmacometabolomics applied to low-dose interleukin-2 treatment in amyotrophic lateral sclerosis

Hugo Alarcan , Clément Bruno , Patrick Emond , Cédric Raoul , Patrick Vourc'H et al.
Annals of the New York Academy of Sciences, 2024, 1536 (1), pp.82-91. ⟨10.1111/nyas.15147⟩
Article dans une revue hal-04767126 v1
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Exercise, disease state and sex influence the beneficial effects of Fn14-depletion on survival and muscle pathology in the SOD1G93A amyotrophic lateral sclerosis (ALS) mouse model

Gareth Hazell , Eve Mccallion , Nina Ahlskog , Emma R Sutton , Magnus Okoh et al.
Skeletal Muscle, 2024, 14 (1), pp.23. ⟨10.1186/s13395-024-00356-0⟩
Article dans une revue hal-04767133 v1

Gut metabolomic and microbiota analyses in ALS mice reveal specific metabolites despite the absence of significant gut dysbiosis

Charlotte Veyrat-Durebex , Samira Osman , Yara Al Ojaimi , Philippe Gosset , Camille Dupuy et al.
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 2024, pp.1 - 7. ⟨10.1080/21678421.2024.2433578⟩
Article dans une revue hal-04877256 v1
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Early-Onset, Conjugal, Twin-Discordant, and Clusters of Sporadic ALS: Pathway to Discovery of Etiology via Lifetime Exposome Research

Peter S Spencer , Valerie S Palmer , Glen E Kisby , Emmeline Lagrange , B. Zane Horowitz et al.
Frontiers in Neuroscience, 2023, 17, pp.1005096. ⟨10.3389/fnins.2023.1005096⟩
Article dans une revue hal-04420878 v1
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The Secretome of Human Dental Pulp Stem Cells and Its Components GDF15 and HB-EGF Protect Amyotrophic Lateral Sclerosis Motoneurons against Death

Richard Younes , Youssef Issa , Nadia Jdaa , Batoul Chouaib , Véronique Brugioti et al.
Biomedicines, 2023, 11 (8), pp.2152. ⟨10.3390/biomedicines11082152⟩
Article dans une revue hal-04767169 v1
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Differential effect of Fas activation on spinal muscular atrophy motoneuron death and induction of axonal growth

Salim Benlefki , Richard Younes , Désiré Challuau , Nathalie Bernard-Marissal , Cécile Hilaire et al.
Cellular and Molecular Biology, 2023, 69 (10), pp.1 - 8. ⟨10.14715/cmb/2023.69.10.1⟩
Article dans une revue hal-04916905 v1

Ultrasensitive Digital Immunoassays for SOD1 Conformation in Amyotrophic Lateral Sclerosis

Lisa Morichon , Christophe Hirtz , Laurent Tiers , Alexandre Mezghrani , Cédric Raoul et al.
Bioanalysis, 2023, 15 (15), pp.927-936. ⟨10.4155/bio-2023-0103⟩
Article dans une revue hal-04650869 v1
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ALS-Associated KIF5A Mutation Causes Locomotor Deficits Associated with Cytoplasmic Inclusions, Alterations of Neuromuscular Junctions, and Motor Neuron Loss

Laurent Soustelle , Franck Aimond , Cristina López-Andrés , Véronique Brugioti , Cédric Raoul et al.
Journal of Neuroscience, 2023, 43 (47), pp.8058 - 8072. ⟨10.1523/jneurosci.0562-23.2023⟩
Article dans une revue hal-04767178 v1
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Muscle cells of sporadic amyotrophic lateral sclerosis patients secrete neurotoxic vesicles

Laura Le Gall , William J Duddy , Cecile Martinat , Virginie Mariot , Owen Connolly et al.
Journal of Cachexia, Sarcopenia and Muscle, 2022, 13 (2), pp.1385 - 1402. ⟨10.1002/jcsm.12945⟩
Article dans une revue hal-04767184 v1
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Cerebellar pathology in motor neuron disease: neuroplasticity and neurodegeneration

Rangariroyashe H Chipika , Grainne Mulkerrin , Pierre-François Pradat , Aizuri Murad , Fabrice Ango et al.
Neural Regeneration Research, 2022, 17 (11), pp.2335-2341. ⟨10.4103/1673-5374.336139⟩
Article dans une revue hal-04767194 v1
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Prionoids in amyotrophic lateral sclerosis

Philippe Gosset , William Camu , Cédric Raoul , Alexandre Mezghrani
Brain Communications, 2022, 4 (3), pp.1 - 16. ⟨10.1093/braincomms/fcac145⟩
Article dans une revue inserm-03697999 v1
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Astrocyte‐targeting RNA interference against mutated superoxide dismutase 1 induces motoneuron plasticity and protects fast‐fatigable motor units in a mouse model of amyotrophic lateral sclerosis

Cylia Rochat , Nathalie Bernard-Marissal , Emma Källstig , Sylvain Pradervand , Florence E. Perrin et al.
Glia, 2022, 70 (5), pp.842 - 857. ⟨10.1002/glia.24140⟩
Article dans une revue hal-03511644 v1
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Identification of secreted factors in dental pulp cell-conditioned medium optimized for neuronal growth

Batoul Chouaib , Pierre-Yves Collart-Dutilleul , Nicolas Blanc-Sylvestre , Richard Younes , Csilla Gergely et al.
Neurochemistry International, 2021, 144, pp.104961. ⟨10.1016/j.neuint.2021.104961⟩
Article dans une revue hal-03147027 v1
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Amyotrophic Lateral Sclerosis Genes in Drosophila melanogaster

Sophie Layalle , Laetitia They , Sarah Ourghani , Cédric Raoul , Laurent Soustelle
International Journal of Molecular Sciences, 2021, 22 (2), pp.904. ⟨10.3390/ijms22020904⟩
Article dans une revue inserm-03169103 v1
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How Degeneration of Cells Surrounding Motoneurons Contributes to Amyotrophic Lateral Sclerosis

Roxane Crabé , Franck Aimond , Philippe Gosset , Frédérique Scamps , Cédric Raoul
Cells, 2020, 9 (12), pp.2550. ⟨10.3390/cells9122550⟩
Article dans une revue inserm-03169112 v1
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Premature termination codons in SOD1 causing Amyotrophic Lateral Sclerosis are predicted to escape the nonsense-mediated mRNA decay

Claire Guissart , Kevin Mouzat , Jovana Kantar , Baptiste Louveau , Paul Vilquin et al.
Scientific Reports, 2020, 10 (1), pp.20738. ⟨10.1038/s41598-020-77716-5⟩
Article dans une revue inserm-03171291 v1
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Spinal Motoneuron TMEM16F Acts at C-boutons to Modulate Motor Resistance and Contributes to ALS Pathogenesis

Claire Soulard , Céline Salsac , Kevin Mouzat , Cécile Hilaire , Julien Roussel et al.
Cell Reports, 2020, 30 (8), pp.2581-2593.e7. ⟨10.1016/j.celrep.2020.02.001⟩
Article dans une revue inserm-03170027 v1

Theme 4 In vivo experimental models

Aleksandra Chudinova , Mireille Rossel , Annette C Vergunst , Gwendal Le Masson , William Camu et al.
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 2019, 20 (sup1), pp.160-187. ⟨10.1080/21678421.2019.1646992⟩
Article dans une revue hal-02364883 v1
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Regulation of Brain Cholesterol: What Role Do Liver X Receptors Play in Neurodegenerative Diseases?

Kevin Mouzat , Aleksandra Chudinova , Anne Polge , Jovana Kantar , William Camu et al.
International Journal of Molecular Sciences, 2019, 20 (16), pp.3858. ⟨10.3390/ijms20163858⟩
Article dans une revue inserm-03171292 v1
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Cytotoxic CD8 + T lymphocytes expressing ALS-causing SOD1 mutant selectively trigger death of spinal motoneurons

Emmanuelle Coque , Céline Salsac , Gabriel Espinosa-Carrasco , Bela Varga , Nicolas Degauque et al.
Proceedings of the National Academy of Sciences of the United States of America, 2019, 116 (6), pp.2312-2317. ⟨10.1073/pnas.1815961116⟩
Article dans une revue inserm-03171288 v1
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Myotube elasticity of an amyotrophic lateral sclerosis mouse model

Bela Varga , Marta Martin-Fernandez , Cécile Hilaire , Ana Sánchez-Vicente , Julie Areias et al.
Scientific Reports, 2018, ⟨10.1038/s41598-018-24027-5⟩
Article dans une revue hal-01775215 v1

Liver X Receptor Genes Variants Modulate ALS Phenotype

Kevin Mouzat , Nicolas Molinari , Jovana Kantar , Anne Polge , Philippe Corcia et al.
Molecular Neurobiology, 2018, 55 (3), pp.1959 - 1965. ⟨10.1007/s12035-017-0453-2⟩
Article dans une revue hal-01821271 v1

The Metabolic Disturbances of Motoneurons Exposed to Glutamate

Sylvie Mavel , Blandine Madji Hounoum , Hélène Blasco , Emmanuelle Coque , Patrick Vourc’h et al.
Molecular Neurobiology, 2018, ⟨10.1007/s12035-018-0945-8⟩
Article dans une revue hal-01826389 v1
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Wildtype motoneurons, ALS‐Linked SOD1 mutation and glutamate profoundly modify astrocyte metabolism and lactate shuttling

Blandine Madji Hounoum , Sylvie Mavel , Emmanuelle Coque , Franck Patin , Patrick Vourc’h et al.
Glia, 2017, 65 (4), pp.592 - 605. ⟨10.1002/glia.23114⟩
Article dans une revue hal-04767249 v1

KCC3 loss-of-function contributes to Andermann syndrome by inducing activity-dependent neuromuscular junction defects

Melissa Bowerman , Céline Salsac , Véronique Bernard , Claire Soulard , Annie Dion et al.
Neurobiology of Disease, 2017, 106, pp.35 - 48. ⟨10.1016/j.nbd.2017.06.013⟩
Article dans une revue hal-01759835 v1
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NSC-34 Motor Neuron-Like Cells Are Unsuitable as Experimental Model for Glutamate-Mediated Excitotoxicity

Blandine Madji Hounoum , Patrick Vourc’h , Romain Felix , Philippe Corcia , Franck Patin et al.
Frontiers in Cellular Neuroscience, 2016, 10, pp.118. ⟨10.3389/fncel.2016.00118⟩
Article dans une revue hal-04767258 v1
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Liver X receptors: from cholesterol regulation to neuroprotection—a new barrier against neurodegeneration in amyotrophic lateral sclerosis?

Kevin Mouzat , Cédric Raoul , Anne Polge , Jovana Kantar , William Camu et al.
Cellular and Molecular Life Sciences, 2016, 73 (20), pp.3801 - 3808. ⟨10.1007/s00018-016-2330-y⟩
Article dans une revue hal-04767259 v1
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Fxyd2 regulates Aδ- and C-fiber mechanosensitivity and is required for the maintenance of neuropathic pain

Stéphanie Venteo , Sophie Laffray , Christiane Wetzel , Cyril Rivat , Frédérique Scamps et al.
Scientific Reports, 2016, 6, pp.36407. ⟨10.1038/srep36407⟩
Article dans une revue hal-01940962 v1
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NSC-34 Motor Neuron-Like Cells Are Unsuitable as Experimental Model for Glutamate-Mediated Excitotoxicity

Blandine Madji Hounoum , Patrick Vourc’h , Romain Félix , Philippe Corcia , Franck Patin et al.
Frontiers in Cellular Neuroscience, 2016, 10, pp.118. ⟨10.3389/fncel.2016.00118⟩
Article dans une revue hal-01826430 v1
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Morphology and Intrinsic Excitability of Regenerating Sensory and Motor Neurons Grown on a Line Micropattern

Ouafa Benzina , Thierry Cloitre , Marta Martin , Cedric Raoul , Csilla Gergely et al.
PLoS ONE, 2014, 9 (10), pp.e110687. ⟨10.1371/journal.pone.0110687⟩
Article dans une revue hal-01084010 v1
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Cerebrospinal fluid-targeted delivery of neutralizing anti-IFNγ antibody delays motor decline in an ALS mouse model

Belkacem Otsmane , Julianne Aebischer , Anice Moumen , Cédric Raoul
NeuroReport, 2014, 25 (1), pp.49 - 54. ⟨10.1097/wnr.0000000000000043⟩
Article dans une revue hal-04767275 v1
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Neuroimmunity dynamics and the development of therapeutic strategies for amyotrophic lateral sclerosis

Mélissa Bowerman , Thierry Vincent , Frédérique Scamps , Florence E. Perrin , William Camu et al.
Frontiers in Cellular Neuroscience, 2013, 7, pp.214. ⟨10.3389/fncel.2013.00214⟩
Article dans une revue hal-02156121 v1
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Death Receptors in the Selective Degeneration of Motoneurons in Amyotrophic Lateral Sclerosis

Julianne Aebischer , Nathalie Bernard-Marissal , Brigitte Pettmann , Cédric Raoul
Journal of Neurodegenerative Diseases, 2013, 2013, pp.1 - 11. ⟨10.1155/2013/746845⟩
Article dans une revue hal-04767274 v1
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Necdin Protects Embryonic Motoneurons from Programmed Cell Death

Julianne Aebischer , Rachel Sturny , David Andrieu , Anne Rieusset , Fabienne Schaller et al.
PLoS ONE, 2011, 6 (9), pp.e23764. ⟨10.1371/journal.pone.0023764⟩
Article dans une revue hal-03437018 v1
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IFNγ triggers a LIGHT-dependent selective death of motoneurons contributing to the non-cell-autonomous effects of mutant SOD1

Cedric Raoul , Julianne Aebischer , Patricia Cassina , Belkacem Otsmane , Anice Moumen et al.
Cell Death and Differentiation, 2010, ⟨10.1038/cdd.2010.143⟩
Article dans une revue hal-00592289 v1
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Chronic activation in presymptomatic amyotrophic lateral sclerosis (ALS) mice of a feedback loop involving Fas, Daxx, and FasL.

Cédric Raoul , Emmanuelle Buhler , Christel Sadeghi , Arnaud Jacquier , Patrick Aebischer et al.
Proceedings of the National Academy of Sciences of the United States of America, 2006, 103 (15), pp.6007-12. ⟨10.1073/pnas.0508774103⟩
Article dans une revue inserm-00195972 v1
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Lentiviral-mediated silencing of SOD1 through RNA interference retards disease onset and progression in a mouse model of ALS.

Cédric Raoul , Toufik Abbas-Terki , Jean-Charles Bensadoun , Sandrine Guillot , Georg Haase et al.
Nature Medicine, 2005, 11 (4), pp.423-8. ⟨10.1038/nm1207⟩
Article dans une revue inserm-00484530 v1

Fas/tumor necrosis factor receptor death signaling is required for axotomy-induced death of motoneurons in vivo.

Gabriele Ugolini , Cédric Raoul , Anna Ferri , Christine Haenggeli , Yoichi Yamamoto et al.
Journal of Neuroscience, 2003, 23 (24), pp.8526-31
Article dans une revue hal-00323583 v1