Céline Colacios

36
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Affiliation actuelle
  • Centre de Recherches en Cancérologie de Toulouse (CRCT)
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Publications

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TNF signature in advanced melanoma patients treated with immune checkpoint inhibitors: Results from the MELANFα clinical study

Mathieu Virazels , Amélie Lusque , Stéphanie Brayer , Matthieu Genais , Carine Dufau et al.
International Journal of Cancer, 2025, ⟨10.1002/ijc.35416⟩
Article dans une revue (data paper) hal-04996473 v1
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Neutral Sphingomyelinase 2 Heightens Anti-Melanoma Immune Responses and Anti–PD-1 Therapy Efficacy

Anne Montfort , Florie Bertrand , Julia Rochotte , Julia Gilhodes , Thomas Filleron et al.
Cancer Immunology Research, 2021, 9 (5), pp.568-582. ⟨10.1158/2326-6066.CIR-20-0342⟩
Article dans une revue inserm-03402255 v1

Combining Nivolumab and Ipilimumab with Infliximab or Certolizumab in Patients with Advanced Melanoma: First Results of a Phase Ib Clinical Trial

Anne Montfort , Thomas Filleron , Mathieu Virazels , Carine Dufau , Jean Milhès et al.
Clinical Cancer Research, 2021, 27 (4), pp.1037-1047. ⟨10.1158/1078-0432.CCR-20-3449⟩
Article dans une revue hal-05027315 v1
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Thrombospondin-1 Silencing Improves Lymphocyte Infiltration in Tumors and Response to Anti-PD-1 in Triple-Negative Breast Cancer

Elie Marcheteau , Thomas Farge , Michaël Pérès , Guillaume Labrousse , Julie Tenet et al.
Cancers, 2021, 13 (16), pp.4059. ⟨10.3390/cancers13164059⟩
Article dans une revue inserm-04971585 v1

Combining TNF blockade with immune checkpoint inhibitors in patients with cancer

Anne Montfort , Mathieu Virazels , Céline Colacios , Nicolas Meyer , Bruno Ségui
Nature Reviews Rheumatology, 2021, 17 (9), pp.577-577. ⟨10.1038/s41584-021-00653-8⟩
Article dans une revue (article de synthèse) hal-04960542 v1
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Resistance of melanoma to immune checkpoint inhibitors is overcome by targeting the sphingosine kinase-1

Caroline Imbert , Anne Montfort , Marine Fraisse , Elie Marcheteau , Julia Gilhodes et al.
Nature Communications, 2020, 11 (1), pp.437. ⟨10.1038/s41467-019-14218-7⟩
Article dans une revue inserm-02492179 v1
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The TNF Paradox in Cancer Progression and Immunotherapy

Anne Montfort , Céline Colacios , Thierry Levade , Nathalie Andrieu-Abadie , Nicolas Meyer et al.
Frontiers in Immunology, 2019, 10, pp.1818. ⟨10.3389/fimmu.2019.01818⟩
Article dans une revue inserm-04905614 v1
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Sphingomyelin Synthase 1 (SMS1) Downregulation Is Associated With Sphingolipid Reprogramming and a Worse Prognosis in Melanoma

Fatima Bilal , Anne Montfort , Julia Gilhodes , Virginie Garcia , Joelle Riond et al.
Frontiers in Pharmacology, 2019, 10, pp.443. ⟨10.3389/fphar.2019.00443⟩
Article dans une revue hal-02332278 v1

The costimulatory molecule CD226 signals through VAV1 to amplify TCR signals and promote IL-17 production by CD4(+) T cells

Guillaume Gaud , Romain Roncagalli , Karima Chaoui , Isabelle Bernard-Cadenat , Julien Familiades et al.
Science Signaling, 2018, 11 (538), ⟨10.1126/scisignal.aar3083⟩
Article dans une revue hal-02117993 v1

The costimulatory molecule CD226 signals through VAV1 to amplify TCR signals and promote IL-17 production by CD4 + T cells

Guillaume Gaud , Romain Roncagalli , Karima Chaoui , Isabelle Bernard , Julien Familiades et al.
Science Signaling, 2018, 11 (538), pp.eaar3083. ⟨10.1126/scisignal.aar3083⟩
Article dans une revue inserm-04284289 v1
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A Natural Variant of the Signaling Molecule Vav1 Enhances Susceptibility to Myasthenia Gravis and Influences the T Cell Receptor Repertoire

Isabelle Bernard , Antoine Sacquin , Sahar Kassem , Mehdi Benamar , Celine Colacios et al.
Frontiers in Immunology, 2018, 9, pp.2399. ⟨10.3389/fimmu.2018.02399⟩
Article dans une revue inserm-02439866 v1
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TNFα blockade overcomes resistance to anti-PD-1 in experimental melanoma

Florie Bertrand , Anne Montfort , Elie Marcheteau , Caroline Imbert , Julia Gilhodes et al.
Nature Communications, 2017, 8 (1), pp.2256. ⟨10.1038/s41467-017-02358-7⟩
Article dans une revue inserm-04905428 v1
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TNFα blockade overcomes resistance to anti-PD-1 in experimental melanoma

Florie Bertrand , Anne Montfort , Elie Marcheteau , Caroline Imbert , Julia Gilhodes et al.
Nature Communications, 2017, 8 (1), ⟨10.1038/s41467-017-02358-7⟩
Article dans une revue hal-04866756 v1
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A Natural Variant of the T Cell Receptor-Signaling Molecule Vav1 Reduces Both Effector T Cell Functions and Susceptibility to Neuroinflammation

Sahar Kassem , Guillaume Gaud , Isabelle Bernard-Cadenat , Mehdi Benamar , Anne S. Dejean et al.
PLoS Genetics, 2016, 12 (7), ⟨10.1371/journal.pgen.1006185⟩
Article dans une revue hal-01438135 v1
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A spontaneous mutation of the rat Themis gene leads to impaired function of regulatory T cells linked to inflammatory bowel disease.

Marianne Chabod , Christophe Pedros , Lucille Lamouroux , Céline Colacios , Isabelle Bernard-Cadenat et al.
PLoS Genetics, 2012, 8 (1), pp.e1002461. ⟨10.1371/journal.pgen.1002461⟩
Article dans une revue hal-02650348 v1
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A Spontaneous Mutation of the Rat Themis Gene Leads to Impaired Function of Regulatory T Cells Linked to Inflammatory Bowel Disease

Marianne Chabod , Christophe Pedros , Lucille Lamouroux , Céline Colacios , Isabelle Bernard et al.
PLoS Genetics, 2012, 8 (1), pp.e1002461. ⟨10.1371/journal.pgen.1002461⟩
Article dans une revue inserm-04284166 v1

The p.Arg63Trp polymorphism controls Vav1 functions and Foxp3 regulatory T cell development

Céline Colacios , Audrey Casemayou , Anne Dejean , Frédérique Gaits-Iacovoni , Christophe Pedros et al.
Journal of Experimental Medicine, 2011, 208 (11), pp.2183-2191. ⟨10.1084/jem.20102191⟩
Article dans une revue inserm-04284249 v1

The rat Toxo1 locus directs toxoplasmosis outcome and controls parasite proliferation and spreading by macrophage-dependent mechanisms.

Pierre Cavaillès , Véronique Sergent , Cordelia Bisanz , Olivier Papapietro , Céline Colacios et al.
Proceedings of the National Academy of Sciences of the United States of America, 2006, 103 (3), pp.744-9. ⟨10.1073/pnas.0506643103⟩
Article dans une revue hal-00171244 v1

[The rat Toxo1 locus controls the outcome of the toxoplasmic infection according to a mendelian mode]

Pierre Cavaillès , Cordelia Bisanz , Olivier Papapietro , Céline Colacios , Véronique Sergent et al.
Médecine/Sciences, 2006, 22 (8-9), pp.679-80
Article dans une revue hal-00171242 v1

Targeting ceramide metabolism in melanoma to improve the efficacy of immune checkpoint inhibitor therapy: from basic mechanisms to the clinic.

Bruno Ségui , Carine Dufau , Benjamin Jung , Matthieu Genais , Thierry Levade et al.
XV SPHINGOLIPID CLUB MEETING, Sep 2024, Erlangen-Nürnberg, Germany
Communication dans un congrès hal-04974692 v1

Triple combination of anti-CTLA-4, anti-PD-1 and anti-TNF in mouse melanoma models and advanced melanoma patients.

Bruno Ségui , Anne Montfort , Mathieu Virazels , Matthieu Genais , Amélie Lusque et al.
EACR conferences “Defence is the Best Attack: Immuno-Oncology Breakthroughs”, Joan Seoane, May 2023, Barcelona, Spain
Communication dans un congrès hal-04974544 v1

Sphingolipid metabolism in cancer immune surveillance

Céline Colacios
The Lysophospholipid and Related Mediators Conference: From Bench to Clinic, FASEB, Jul 2021, Distanciel, France
Communication dans un congrès hal-04993184 v1

Combining TNF inhibitors to anti-PD-1 and anti-CTLA-4 for the treatment of advanced melanoma patients

Anne Montfort , Mathieu Virazels , Carine Dufau , Stéphanie Brayer , Nathalie Andrieu-Abadie et al.
17ème journées du Cancéropôle Grand Sud-Ouest, Nov 2021, Carcassone, France
Communication dans un congrès hal-04970934 v1

Neutral sphingomyelinase 2 heightens anti-melanoma immune response and synergizes with anti-PD-1.

Anne Montfort , Florie Bertrand , Julia Rochotte , Nathalie Andrieu-Abadie , Thierry Levade et al.
Toulouse Oncoweek, Feb 2020, Toulouse, France
Communication dans un congrès hal-04971026 v1

Ceramide metabolism in melanoma: from basic mechanisms to immunotherapy in advanced melanoma patients.

Bruno Ségui , Anne Montfort , Caroline Imbert , Céline Colacios , Nathalie Andrieu-Abadie et al.
FEBS 2019 Sphingolipid Biology: Sphingolipids in Physiology and Pathology, Giovanni D'Angelo, Christopher J. Clarke, Liana C. Silva, May 2019, Cascais, Portugal
Communication dans un congrès hal-04974329 v1

Resistance of Melanoma to Immune Checkpoint Inhibitors is Overcome by Targeting the Sphingosine Kinase 1

Céline Colacios , Caroline Imbert , Anne Montfort , Marine Fraisse , Elie Marcheteau et al.
Canceropole GSO, Canceropole GSO, Nov 2019, Arcachon, France
Communication dans un congrès hal-04993281 v1

Combining TNF-targeting antibodies to immune checkpoint inhibitors in melanoma

Anne Montfort , Florie Bertrand , Elie Marcheteau , Caroline Imbert , Julia Gilhodes et al.
Toulouse Oncoweek, Feb 2018, Toulouse, France
Communication dans un congrès hal-04970883 v1

Evaluation of the biodistribution of different anti-TNF agents in combination with Immunotherapy in Melanoma model using ImmunoTEP

Céline Colacios , Laure Badier , Carine Pestourie , Bruno Ségui , Isabelle Quelven
Toulouse Onco Week (TOW) Symposium, Feb 2025, Toulouse, France.
Poster de conférence inserm-04973597 v1

TNF plasma levels in advanced melanoma patients treated with immune checkpoint inhibitors: results from the MELANFα clinical study.

Mathieu Virazels , Amélie Lusque , Thomas Filleron , Clara-Maria Scarlata , Maha Ayyoub et al.
Defence is the Best Attack: Immuno-Oncology Breakthroughs, May 2023, Barcelona, France
Poster de conférence hal-04971045 v1

Triple combination of ipilimumab + nivolumab + anti-TNF in treatment naive melanoma patients: Final analysis of TICIMEL, a phase Ib prospective clinical trial

Bruno Ségui , Nicolas Meyer , Amélie Lusque , Mathieu Virazels , Thomas Filleron et al.
ESMO congress 2022, Sep 2022, Paris, France. Annals of Oncology, 33 (suppl_7), pp.S936-S937, 2022, ⟨10.1016/j.annonc.2022.07.972⟩
Poster de conférence hal-04975541 v1

TNF plasma levels in advanced melanoma patients treated with immune checkpoint inhibitors: results from the MELANFα clinical study.

Mathieu Virazels , Anne Montfort , Amélie Lusque , Thomas Filleron , Céline Colacios et al.
ESMO Congress 2022, Sep 2022, Paris, France
Poster de conférence hal-04971055 v1

Combining TNF blockade with immune checkpoint inhibitors in advanced melanoma patients

Mathieu Virazels , Anne Montfort , Thomas Filleron , Carine Dufau , Maha Ayyoub et al.
53rd congress of the French Society of Immunology, Dec 2021, Paris, France
Poster de conférence hal-04970987 v1

Neutral sphingomyelinase 2 heightens anti-melanoma immune response and synergizes with immune checkpoint inhibitors.

Anne Montfort , Florie Bertrand , Julia Rochotte , Nathalie Andrieu-Abadie , Thierry Levade et al.
52ème Congrès de la Société Française d'immunologie (SFI), Nov 2019, Nantes, France
Poster de conférence hal-04970950 v1