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Cancer immunotherapy in elderly patients: the concept of immune senescence challenged by clinical experience
Mathilde Guégan
,
Malvina Bichon
,
Nathalie Chaput
,
Roch Houot
,
Jean Lemoine
Article dans une revue
hal-04891566
v1
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Metabolic tumor volume assessed by 18F FDG - PET CT scan as a predictive biomarker for immune checkpoint blockers in advanced NSCLC and its biological correlates.
Filippo Dall'Olio
,
Wael Zrafi
,
Veronique Roelants
,
Valentina Ambrosini
,
Aloyse Fourquet
et al.
Article dans une revue
(article de synthèse)
hal-04806943
v1
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B cells and the coordination of immune checkpoint inhibitor response in patients with solid tumors
Ronan Flippot
,
Marcus Teixeira
,
Macarena Rey-Cardenas
,
Lucia Carril-Ajuria
,
Larissa Rainho
et al.
Article dans une revue
inserm-04685443
v1
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Human virome profiling identified CMV as the major viral driver of a high accumulation of senescent CD8 + T cells in patients with advanced NSCLC
Marie Naigeon
,
Matthieu Roulleaux Dugage
,
François-Xavier Danlos
,
Lisa Boselli
,
Jean-Mehdi Jouniaux
et al.
Article dans une revue
hal-04719261
v1
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Genomic Instability and Pro-Tumoral Inflammation are associated with Primary Resistance to Anti-PD1 + Anti-Angiogenesis in Malignant Pleural Mesothelioma
Francois-Xavier Danlos
,
Matthieu Texier
,
Bastien Job
,
Severine Mouraud
,
Lydie Cassard
et al.
Article dans une revue
hal-03972355
v1
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Overcoming resistance to αPD-1 of MMR-deficient tumors with high tumor-induced neutrophils levels by combination of αCTLA-4 and αPD-1 blockers
Laetitia Nebot-Bral
,
Antoine Hollebecque
,
Andrey Yurchenko
,
Louise de Forceville
,
Mathieu Danjou
et al.
Article dans une revue
hal-03852523
v1
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Overcoming resistance to αPD-1 of MMR-deficient tumors with high tumor-induced neutrophils levels by combination of αCTLA-4 and αPD-1 blockers
Laetitia Nebot-Bral
,
Antoine Hollebecque
,
Andrey A Yurchenko
,
Louise de Forceville
,
Mathieu Danjou
et al.
Article dans une revue
hal-03853375
v1
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Plasma CD27, a Surrogate of the Intratumoral CD27–CD70 Interaction, Correlates with Immunotherapy Resistance in Renal Cell Carcinoma
Nadine Benhamouda
,
Ikuan Sam
,
Nicolas Epaillard
,
Alain Gey
,
Letuan Phan
et al.
Article dans une revue
pasteur-04142515
v1
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Association of AXL and PD-L1 Expression with Clinical Outcomes in Patients with Advanced Renal Cell Carcinoma Treated with PD-1 Blockade
Stéphane Terry
,
Cécile Dalban
,
Nathalie Rioux-Leclercq
,
Julien Adam
,
Maxime Meylan
et al.
Article dans une revue
hal-03477307
v1
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Cancer and immunotherapy: a role for microbiota composition
Fiona Pham
,
Fabien Moinard-Butot
,
Clélia Coutzac
,
Nathalie Chaput
Article dans une revue
hal-04099088
v1
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Systemic short chain fatty acids limit antitumor effect of CTLA-4 blockade in hosts with cancer
Clélia Coutzac
,
Jean Mehdi Jouniaux
,
Angelo Paci
,
Julien Schmidt
,
Domenico Mallardo
et al.
Article dans une revue
hal-03109210
v1
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Interleukin‐7/Interferon axis drives T‐cell and salivary gland epithelial cell interactions in Sjögren’s syndrome
Elodie Rivière
,
Juliette Pascaud
,
Alexandre Virone
,
Anastasia Dupré
,
Bineta Ly
et al.
Article dans une revue
pasteur-03036519
v1
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Why is immunotherapy effective (or not) in patients with MSI/MMRD tumors?
Laetitia Nebot-Bral
,
Clélia Coutzac
,
Patricia L Kannouche
,
Nathalie Chaput
Article dans une revue
hal-02425478
v1
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IL-15 superagonist RLI has potent immunostimulatory properties on NK cells: implications for antimetastatic treatment
Mélanie Desbois
,
Coralie Béal
,
Mélinda Charrier
,
Benjamin Besse
,
Guillaume Meurice
et al.
Article dans une revue
inserm-03498336
v1
|
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Estimating causal effects of time-dependent exposures on a binary endpoint in a high-dimensional setting
Vahé Asvatourian
,
Clélia Coutzac
,
Nathalie Chaput
,
Caroline Robert
,
Stefan Michiels
et al.
Article dans une revue
inserm-02310420
v1
|
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Enterocolitis due to immune checkpoint inhibitors: a systematic review
Emilie Soularue
,
Patricia Lepage
,
Jean-Fréderic Colombel
,
Clelia Coutzac
,
David Faleck
et al.
Article dans une revue
hal-02626171
v1
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Deep phenotyping of immune cell populations by optimized and standardized flow cytometry analyses
Fabien Pitoiset
,
Lydie Cassard
,
Karim El Soufi
,
Lisa Boselli
,
Jonathan Grivel
et al.
Article dans une revue
hal-01955310
v1
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Baseline gut microbiota predicts clinical response and colitis in metastatic melanoma patients treated with ipilimumab
Nathalie Chaput
,
Patricia Lepage
,
Clelia Coutzac
,
E Soularue
,
Karine Le Roux
et al.
Article dans une revue
hal-01604339
v1
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Colon Immune-Related Adverse Events: Anti-CTLA-4 and Anti-PD-1 Blockade Induce Distinct Immunopathological Entities
Clelia Coutzac
,
Julien Adam
,
Emilie Soularue
,
Michael Collins
,
Antoine Racine
et al.
Article dans une revue
hal-02625648
v1
|
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Inflammatory bowel disease and cancer response due to anti-CTLA-4: is it in the flora?
Franck Carbonnel
,
Emilie Soularue
,
Clélia Coutzac
,
Nathalie Chaput
,
Christine Mateus
et al.
Article dans une revue
(article de synthèse)
hal-01607061
v1
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Dendritic cell-derived exosomes as maintenance immunotherapy after first line chemotherapy in NSCLC
Benjamin Besse
,
Melinda Charrier
,
Valerie Lapierre
,
Eric Dansin
,
Olivier Lantz
et al.
Article dans une revue
hal-01440237
v1
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IL-15 Trans-Signaling with the Superagonist RLI Promotes Effector/Memory CD8+ T Cell Responses and Enhances Antitumor Activity of PD-1 Antagonists
Mélanie Desbois
,
Pauline Le Vu
,
Clélia Coutzac
,
Elie Marcheteau
,
Coralie Béal
et al.
Article dans une revue
inserm-01823361
v1
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Anticancer immunotherapy by CTLA-4 blockade: obligatory contribution of IL-2 receptors and negative prognostic impact of soluble CD25
Dalil Hannani
,
Marie Vétizou
,
David Enot
,
Sylvie Rusakiewicz
,
Nathalie Chaput
et al.
Article dans une revue
hal-02047405
v1
|
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Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota
Marie Vétizou
,
Jonathan M. Pitt
,
Romain Daillere
,
Patricia Lepage
,
Nadine Waldschmitt
et al.
Article dans une revue
hal-02639698
v1
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Regulation of CD4+NKG2D+ Th1 Cells in Patients with Metastatic Melanoma Treated with Sorafenib: Role of IL-15Rα and NKG2D Triggering
Ana I Romero
,
Nathalie Chaput
,
Vichnou Poirier-Colame
,
Sylvie Rusakiewicz
,
Nicolas Jacquelot
et al.
Article dans une revue
inserm-02442721
v1
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Alternatively spliced NKp30 isoforms affect the prognosis of gastrointestinal stromal tumors.
Nicolas F Delahaye
,
Sylvie Rusakiewicz
,
Isabelle Martins
,
Cédric Ménard
,
Stephan Roux
et al.
Article dans une revue
hal-00665651
v1
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Contribution of IL-17-producing {gamma}{delta} T cells to the efficacy of anticancer chemotherapy.
Yuting Ma
,
Laetitia Aymeric
,
Clara Locher
,
Stephen R Mattarollo
,
Nicolas F Delahaye
et al.
Article dans une revue
pasteur-00576679
v1
|
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Updated Technology to Produce Highly Immunogenic Dendritic Cell-derived Exosomes of Clinical Grade
Sophie Viaud
,
Stéphanie Ploix
,
Valérie Lapierre
,
Clotilde Théry
,
Pierre-Henri Commere
et al.
Article dans une revue
hal-03272286
v1
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Opposing effects of toll-like receptor (TLR3) signaling in tumors can be therapeutically uncoupled to optimize the anticancer efficacy of TLR3 ligands.
Rosa Conforti
,
Yuting Ma
,
Yannis Morel
,
Carine Paturel
,
Magali Terme
et al.
Article dans une revue
hal-00591518
v1
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Dendritic Cell-Derived Exosomes Promote Natural Killer Cell Activation and Proliferation: A Role for NKG2D Ligands and IL-15Rα
Sophie Viaud
,
Magali Terme
,
Caroline Flament
,
Julien Taieb
,
Fabrice André
et al.
Article dans une revue
pasteur-03360096
v1
|
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Massive expansion of regulatory T-cells following interleukin 2 treatment during a phase I-II dendritic cell-based immunotherapy of metastatic renal cancer.
François M Lemoine
,
Mustapha Cherai
,
Camille Giverne
,
Dalia Dimitri
,
Michelle Rosenzwajg
et al.
International Journal of Oncology, 2009, 35 (3), pp.569-81
Article dans une revue
hal-00420217
v1
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Natural killer cell IFN-gamma levels predict long-term survival with imatinib mesylate therapy in gastrointestinal stromal tumor-bearing patients.
Cédric Ménard
,
Jean-Yves Blay
,
Christophe Borg
,
Stefan Michiels
,
François Ghiringhelli
et al.
Article dans une revue
inserm-00484764
v1
|
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The dendritic cell-like functions of IFN-producing killer dendritic cells reside in the CD11b+ subset and are licensed by tumor cells.
Magali Terme
,
Grégoire Mignot
,
Evelyn Ullrich
,
Mathieu Bonmort
,
Véronique Minard-Colin
et al.
Article dans une revue
inserm-00451699
v1
|
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The critical role of IL-15 in the antitumor effects mediated by the combination therapy imatinib and IL-2.
Grégoire Mignot
,
Evelyn Ullrich
,
Mathieu Bonmort
,
Cédric Ménard
,
Lionel Apetoh
et al.
Journal of Immunology, 2008, 180 (10), pp.6477-83
Article dans une revue
hal-00364426
v1
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Trans-presentation of IL-15 dictates IFN-producing killer dendritic cells effector functions.
Evelyn Ullrich
,
Mathieu Bonmort
,
Gregoire Mignot
,
Benedikt Jacobs
,
Daniela Bosisio
et al.
Journal of Immunology, 2008, 180 (12), pp.7887-97
Article dans une revue
hal-00363902
v1
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Dendritic cells and innate defense against tumor cells.
Evelyn Ullrich
,
Cédric Ménard
,
Caroline Flament
,
Magali Terme
,
Grégoire Mignot
et al.
Article dans une revue
istex
inserm-00318515
v1
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Killer dendritic cells: IKDC and the others.
Mathieu Bonmort
,
Marc Dalod
,
Grégoire Mignot
,
Evelyn Ullrich
,
Nathalie Chaput
et al.
Article dans une revue
istex
hal-00294468
v1
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Therapy-induced tumor immunosurveillance involves IFN-producing killer dendritic cells.
Evelyn Ullrich
,
Mathieu Bonmort
,
Grégoire Mignot
,
Nathalie Chaput
,
Julien Taieb
et al.
Article dans une revue
inserm-00451703
v1
|
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Chemoimmunotherapy of Tumors: Cyclophosphamide Synergizes with Exosome Based Vaccines
Julien Taieb
,
Nathalie Chaput
,
Noël Schartz
,
Stéphan Roux
,
Sophie Novault
et al.
Article dans une revue
pasteur-03360098
v1
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CD4<b>+</b>CD25<b>+</b> regulatory T cells inhibit natural killer cell functions in a transforming growth factor–β–dependent manner
François Ghiringhelli
,
Cédric Ménard
,
Magali Terme
,
Caroline Flament
,
Julien Taieb
et al.
Article dans une revue
inserm-04685415
v1
|
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Caspase-dependent immunogenicity of doxorubicin-induced tumor cell death
Noelia Casares
,
Marie O Pequignot
,
Antoine Tesniere
,
François Ghiringhelli
,
Stéphan Roux
et al.
Article dans une revue
inserm-04685411
v1
|
|
The potential of exosomes in immunotherapy of cancer
Nathalie Chaput
,
Julien Taïeb
,
Noël Schartz
,
Caroline Flament
,
Sophie Novault
et al.
Article dans une revue
istex
pasteur-03360103
v1
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Vaccination of metastatic melanoma patients with autologous dendritic cell (DC) derived-exosomes: results of thefirst phase I clinical trial.
Bernard Escudier
,
Thierry Dorval
,
Nathalie Chaput
,
Fabrice André
,
Marie-Pierre Caby
et al.
Article dans une revue
inserm-00092539
v1
|
|
Immune response against dying tumor cells.
Laurence Zitvogel
,
Noelia Casares
,
Marie O Péquignot
,
Nathalie Chaput
,
Matthew L Albert
et al.
Article dans une revue
pasteur-01402386
v1
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