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UBE2N: Hope on the Cancer Front, How to Inhibit This Promising Target Prospect?
Florian Schwalen
,
Côme Ghadi
,
Léonie Ibazizene
,
Shafi Ullah Khan
,
Jana Sopkova-de Oliveira Santos
et al.
Article dans une revue
hal-04885402v1
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PROTAC 2.0: Expanding the frontiers of targeted protein degradation
Marie Cornu
,
Thomas Lemaitre
,
Charline Kieffer
,
Anne Sophie Voisin-Chiret
Article dans une revue
hal-05472074v1
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Towards New Anti‐inflammatory Agents: Design, Synthesis and Evaluation of Molecules Targeting XIAP‐BIR2
Marc Ragui Farag
,
Nicolas Guedeney
,
Florian Schwalen
,
Aymeric Zadorovnyj
,
Amelie Barczyk
et al.
Article dans une revue
hal-04772005v1
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Molecular glue degraders: exciting opportunities for novel drug discovery
Thomas Lemaitre
,
Marie Cornu
,
Florian Schwalen
,
Marc Since
,
Charline Kieffer
et al.
Article dans une revue
hal-04711906v1
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Target fishing reveals PfPYK-1 and PfRab6 as potential targets of an antiplasmodial 4-anilino-2-trichloromethylquinazoline hit compound
C. Kieffer
,
N. Primas
,
S. Hutter
,
A. Merckx
,
L. Reininger
et al.
Article dans une revue
hal-04503278v1
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PROTAC technology: A new drug design for chemical biology with many challenges in drug discovery
Nicolas Guedeney
,
Marie Cornu
,
Florian Schwalen
,
Charline Kieffer
,
Anne Sophie Voisin-Chiret
Article dans une revue
hal-03936766v1
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Computational Tool to Design Small Synthetic Inhibitors Selective for XIAP-BIR3 Domain
Marc Farag
,
Charline Kieffer
,
Nicolas Guedeney
,
Anne Sophie Voisin-Chiret
,
Jana Sopkova-de Oliveira Santos
Article dans une revue
hal-04222485v1
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Computational Tool to Design Small Synthetic Inhibitors Selective for XIAP-BIR3 Domain
Marc Farag
,
Charline Kieffer
,
Nicolas Guedeney
,
Anne Sophie
,
Jana Sopkova-de Oliveira Santos
Article dans une revue
hal-04148037v1
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Noncellular screening for the discovery of protein–protein interaction modulators
Charline Kieffer
,
Jean Pierre Jourdan
,
Marie Jouanne
,
Anne Sophie Voisin-Chiret
Article dans une revue
hal-03493870v1
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Discovery of new hit-molecules targeting Plasmodium falciparum through a global SAR study of the 4-substituted-2-trichloromethylquinazoline antiplasmodial scaffold
Justine Desroches
,
Charline Kieffer
,
Nicolas Primas
,
Sébastien Hutter
,
Armand Gellis
et al.
Article dans une revue
hal-01416990v1
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Sequential one pot double C H heteroarylation of thiophene using bromopyridines to synthesize unsymmetrical 2,5-bipyridylthiophenes
Charline Kieffer
,
Victor Babin
,
Marie Jouanne
,
Ikram Slimani
,
Yohann Berhault
et al.
Article dans une revue
istex
hal-02043719v1
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Preventing the contamination of hospital personnel by cytotoxic agents: evaluation and training of the para-professional healthcare workers in oncology units
C. Kieffer
,
Pierre Verhaeghe
,
S. Lagrassa
,
R. Gregoire
,
Z. Moussaoui
et al.
Article dans une revue
istex
hal-01460563v1
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Antileishmanial pharmacomodulation in 8-nitroquinolin-2(1H)-one series
Charline Kieffer
,
Anita Cohen
,
Pierre Verhaeghe
,
Lucie Paloque
,
Sébastien Hutter
et al.
Article dans une revue
istex
hal-01460646v1
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Looking for new antileishmanial derivatives in 8-nitroquinolin-2(1H)-one series
Charline Kieffer
,
Anita Cohen
,
Pierre Verhaeghe
,
Sébastien Hutter
,
Caroline Castera-Ducros
et al.
Article dans une revue
istex
hal-01460569v1
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Synthesis and in vitro evaluation of 4-trichloromethylpyrrolo[1,2-a]quinoxalines as new antiplasmodial agents
Nicolas Primas
,
Peggy Suzanne
,
Pierre Verhaeghe
,
Sébastien Hutter
,
Charline Kieffer
et al.
Article dans une revue
hal-01417058v1
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A new DMAP-catalyzed and microwave-assisted approach for introducing heteroarylamino substituents at position 4 of the quinazoline ring.
Armand Gellis
,
Charline Kieffer
,
Nicolas Primas
,
Gilles Lanzada
,
Michel Giorgi
et al.
Article dans une revue
hal-01417081v1
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Sonogashira cross-coupling reaction in 4-chloro-2-trichloromethylquinazoline series is possible despite a side dimerization reaction
Charline Kieffer
,
Pierre Verhaeghe
,
Nicolas Primas
,
C. Castera-Ducros
,
A. Gellis
et al.
Article dans une revue
istex
hal-00821454v1
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A New Synthetic Route to Original Sulfonamide Derivatives in 2-Trichloromethylquinazoline Series: A Structure-Activity Relationship Study of Antiplasmodial Activity
Nicolas Primas
,
Pierre Verhaeghe
,
Anita Cohen
,
Charline Kieffer
,
Aurélien Dumètre
et al.
Article dans une revue
hal-01772858v1
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