Christelle BERTRAND-GADAY

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Publications

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Targeting Neuroinflammation by Activation of the Sigma-1 Receptor (S1R) and Inhibition of Butyrylcholinesterase (hBChE) Leads to Highly Potent Anti-Amnesic Compounds in an Alzheimer’s Disease Mouse Model

Kora Reichau , Lucie Crouzier , Tina Gehrig , Alix Flake , Eva Schaller et al.

European Journal of Medicinal Chemistry, 2026, 305, pp.118486. ⟨10.1016/j.ejmech.2025.118486⟩

Article dans une revue hal-05454907v1
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Furan fatty acids supplementation in obese mice reverses hepatic steatosis and protects against cartilage degradation

Mathys Chaslin , Georges Maroun , Erwann Durand , Béatrice Bonafos , Said Assou et al.

Biomedicine and Pharmacotherapy, 2025, 187, 13p. ⟨10.1016/j.biopha.2025.118072⟩

Article dans une revue hal-05051861v1
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Resistance and Aerobic Preconditioning Delays Unloading‐Induced Multisystemic Physiological Changes: The NEBULA Project

Théo Fovet , Margot Issertine , Pauline Jacob , Stephanie Ghislin , Norbert Laroche et al.

FASEB Journal, 2025, 39 (13), pp.e70759. ⟨10.1096/fj.202501128R⟩

Article dans une revue hal-05147939v1
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Acute effects of heat intervention and hybrid exercise on protein synthesis, ribosome biogenesis and autophagy

Tom Normand-Gravier , Robert Solsona , Flavie Arnould , Roméo Deriaz , Christelle Bertrand-Gaday et al.

Journal of Thermal Biology, 2025, 131, pp.104169. ⟨10.1016/j.jtherbio.2025.104169⟩

Article dans une revue hal-05164658v1
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The selective butyrylcholinesterase inhibitor UW‐MD‐95 shows symptomatic and neuroprotective effects in a pharmacological mouse model of Alzheimer's disease

Allison Carles , Matthias Hoffmann , Matthias Scheiner , Lucie Crouzier , Christelle Bertrand‐gaday et al.

CNS Neuroscience & Therapeutics, 2024, 30 (6), pp.e14814. ⟨10.1111/cns.14814⟩

Article dans une revue hal-04628744v1
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Insight into the Role of Gut Microbiota in Duchenne Muscular Dystrophy

Maxence Jollet , Mahendra Mariadassou , Olivier Rué , Laurence Pessemesse , Vincent Ollendorff et al.

American Journal of Pathology, 2024, 194 (2), pp.264-279. ⟨10.1016/j.ajpath.2023.10.010⟩

Article dans une revue hal-04383411v1
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Furan fatty acid extracted from Hevea brasiliensis latex increases muscle mass in mice

François Pelletier , Erwann Durand , Jatuporn Chaiyut , Clémence Bronstein , Laurent Vaysse et al.

Biomedicine and Pharmacotherapy, 2023, 166, pp.115330. ⟨10.1016/j.biopha.2023.115330⟩

Article dans une revue hal-04185474v1
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Preventive nutritional supplementation with furan fatty acid in a DIO mouse model increases muscle mass and reduces metabolic disorders

Laetitia Dore , Erwann Durand , Béatrice Bonafos , Jatuporn Chaiyut , Laurent Vaysse et al.

Biomedicine and Pharmacotherapy, 2023, 164, pp.114945. ⟨10.1016/j.biopha.2023.114945⟩

Article dans une revue hal-04114554v1
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9-PAHPA long term intake in DIO and db/db mice ameliorates insulin sensitivity but has few effects on obesity and associated metabolic disorders

Béatrice Bonafos , Antonio Cortés-Espinar , Laurence Balas , Laurence Pessemesse , Karen Lambert et al.

Journal of Nutritional Biochemistry, 2023, 112, pp.109216. ⟨10.1016/j.jnutbio.2022.109216⟩

Article dans une revue hal-03876073v1
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A single short reprogramming early in life initiates and propagates an epigenetically related mechanism improving fitness and promoting an increased healthy lifespan

Quentin Alle , Enora Le Borgne , Paul Bensadoun , Camille Lemey , Nelly Béchir et al.

Aging Cell, 2022, 12p. ⟨10.1111/acel.13714⟩

Article dans une revue hal-03819049v1
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Myostatin gene inactivation increases post-mortem calpain-dependent muscle proteolysis in mice

Rim Nassar , Barbara Vernus , Gilles Carnac , Gilles Fouret , Bénédicte Goustard et al.

Meat Science, 2022, 185, pp.108726. ⟨10.1016/j.meatsci.2021.108726⟩

Article dans une revue hal-03503780v1
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p43, a Truncated Form of Thyroid Hormone Receptor α, Regulates Maturation of Pancreatic β Cells

Emilie Blanchet , Laurence Pessemesse , Christine Feillet-Coudray , Charles Coudray , Chantal Cabello et al.

International Journal of Molecular Sciences, 2021, 22 (5), ⟨10.3390/ijms22052489⟩

Article dans une revue hal-03184462v1
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Transient Changes of Metabolism at the Pronuclear Stage in Mice Influences Skeletal Muscle Phenotype in Adulthood

Christelle Bertrand-Gaday , Martine Letheule , Emilie Blanchet , Barbara Vernus , Laurence Pessemesse et al.

International Journal of Molecular Sciences, 2020, 21 (19), ⟨10.3390/ijms21197203⟩

Article dans une revue hal-02973322v1
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Acute and chronic effects of Rhaponticum carthamoides and Rhodiola rosea extracts supplementation coupled to resistance exercise on muscle protein synthesis and mechanical power in rats

Rémi Roumanille , Barbara Vernus , Thomas Brioche , Vincent Descossy , C.T. van Ba et al.

Journal of the International Society of Sports Nutrition, 2020, 17 (1), ⟨10.1186/s12970-020-00390-5⟩

Article dans une revue hal-03023074v1

eIF3f depletion impedes mouse embryonic development, reduces adult skeletal muscle mass and amplifies muscle loss during disuse

Aurélie Docquier , Laura Pavlin , Audrey Raibon , Christelle Bertrand-Gaday , Chamroeun Sar et al.

The Journal of Physiology, 2019, 597 (12), pp.3107-3131. ⟨10.1113/JP277841⟩

Article dans une revue hal-02269495v1
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New evidence of exercise training benefits in myostatin-deficient mice: Effect on lipidomic abnormalities

Narjes Baati , Christine Coudray , Gilles Fouret , Barbara Vernus , Benedicte Goustard et al.

Biochemical and Biophysical Research Communications, 2019, 516, pp.89-95. ⟨10.1016/j.bbrc.2019.06.014⟩

Article dans une revue hal-02268413v1
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Mitochondrial MDM2 regulates respiratory complex i activity independently of p53

Giuseppe Arena , Madi Yann Cisse , Samuel Pyrdziak , Laurent Chatre , Romain Riscal et al.

Molecular Cell, 2018, 69 (4), pp.594-609. ⟨10.1016/j.molcel.2018.01.023⟩

Article dans une revue hal-01837662v1

Learning performances and vulnerability to amyloid toxicity in acetylcholinesterase and butyrylcholinesterase knockout mice

Tangui Maurice , Manon Strehaiano , Nathalie Siméon , Christelle Bertrand , Arnaud Chatonnet

Journal of Neurochemistry, 2017, 142 (Aout), pp.197-197. ⟨10.1111/jnc.13925⟩

Article dans une revue hal-01604889v1

Temperature homeostasis in mice lacking the p43 mitochondrial T3 receptor

Christelle Bertrand-Gaday , Laurence Pessemesse , Gérard Cabello , Chantal Wrutniak Cabello , François Casas

FEBS Letters, 2016, 590 (7), pp.982-991. ⟨10.1002/1873-3468.12129⟩

Article dans une revue hal-03101950v1

Learning performances and vulnerability to amyloid toxicity in the butyrylcholinesterase knockout mouse

Tangui Maurice , Manon Strehaiano , Nathalie Siméon , Christelle Bertrand , Arnaud Chatonnet

Behavioural Brain Research, 2016, 296, pp.351-360. ⟨10.1016/j.bbr.2015.08.026⟩

Article dans une revue istex hal-01837622v1
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Muscle regeneration with intermuscular adipose tissue (IMAT) accumulation is modulated by mechanical constraints

Allan Pagano , Rémi Demangel , Thomas Brioche , Elodie Jublanc , Christelle Bertrand-Gaday et al.

PLoS ONE, 2015, 10 (12), ⟨10.1371/journal.pone.0144230⟩

Article dans une revue hal-01837620v1
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Mice lacking the p43 mitochondrial T3 receptor become glucose intolerant and insulin resistant during aging

Christelle Bertrand , Emilie Blanchet , Laurence Pessemesse , Jean Sebastien Annicotte , Christine Coudray et al.

PLoS ONE, 2013, 8 (9), ⟨10.1371/journal.pone.0075111⟩

Article dans une revue hal-01189724v1

Mitochondrial T3 receptor p43 regulates insulin secretion and glucose homeostasis

E. Blanchet , Christelle Bertrand , J. S. Annicotte , A. Schlernitzauer , L. Pessemesse et al.

FASEB Journal, 2012, 26 (1), pp.40--50. ⟨10.1096/fj.11-186841⟩

Article dans une revue hal-02193048v1

Genetic ablation of acetylcholinesterase alters muscle function in mice.

Alban Vignaud , Françoise Fougerousse , Etienne Mouisel , Christelle Bertrand , Beatrice Bonafos et al.

Chemico-Biological Interactions, 2008, 175 (1-3), pp.129-30. ⟨10.1016/j.cbi.2008.04.035⟩

Article dans une revue istex hal-00289869v1

Acetylcholinesterase is required for neuronal and muscular development in the zebrafish embryo

M. Behra , Xavier Cousin , Christelle Bertrand , J.L. Vonesch , D. Biellmann et al.

Nature Neuroscience, 2002, 5, pp.111-118

Article dans une revue hal-02680101v1

Acetylcholinesterase is required for neuronal and muscular development in the zebrafish embryo

Martine Behra , Xavier Cousin , Christelle Bertrand , Jean-Luc Vonesch , Dominique Biellmann et al.

Nature Neuroscience, 2002, 5 (2), pp.111-118. ⟨10.1038/nn788⟩

Article dans une revue hal-04131724v1
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Zebrafish acetylcholinesterase is encoded by a single gene localized on linkage group 7. Gene structure and polymorphism; molecular forms and expression pattern during development

Christelle Bertrand , Arnaud Chatonnet , Christina Takke , Yilin Yan , John H Postlethwait et al.

Journal of Biological Chemistry, 2001, 276 (1), pp.464-474. ⟨10.1074/jbc.M006308200⟩

Article dans une revue hal-02681242v1

Anti-apoptotic activity of p53 maps to the COOH-terminal domain and is retained in a highly oncogenic natural mutant

Patrice Lassus , Christelle Bertrand , Olivier Zugasti , Jean-Philippe Chambon , Thierry Soussi et al.

Oncogene, 1999, 18 (33), pp.4699-4709. ⟨10.1038/sj.onc.1202841⟩

Article dans une revue hal-03101969v1

L'acétylcholinestérase des poissons, cible des organophosphorés et des carbamates. Caractérisation du gène et des formes moléculaires de l'enzyme chez Danio rerio. Effets des anticholinestérasiques

Christelle Bertrand , Xavier Cousin , E. Haubruge , J.P. Toutant , Arnaud Chatonnet

BFPP. Bulletin français de la pêche et de la protection des milieux aquatiques [Bulletin francais de la pêche et de la pisciculture], 1998, 350-351, pp.535-546

Article dans une revue hal-02696512v1

Single-cell atlas of aged murine synovial joints reveals macrophage deficits as key drivers of synovial fibrosis

Olivier Bortolotti , Lea Marineche , Bienfait Abasi Ali , Christelle Bertrand-Gaday , Dany Severac et al.

2025 World Congress on Osteoarthritis, OARSI, Osteoarthritis Research Society International, Apr 2025, Incheon, South Korea. pp.806-807, ⟨10.1016/j.joca.2025.03.063⟩

Communication dans un congrès hal-05099269v1

Cardiometabolic potential of furan fatty acid nutritional supplementation in a pre-clinical murine model

L. Dore , Erwann Durand , Béatrice Bonafos , Jatuporn Chaiyut , Laurent Vaysse et al.

18. Congrés de la Nouvelle Société Française d’Athérosclérose, Jun 2023, Biarritz, France

Communication dans un congrès hal-04849220v1

Coordination between mitochondrial-associated membranes MAMs, mitochondrial function and protein synthesis in exercised and myopathic muscles

Marie Colomb , Léa Tuifua , Christelle Bertrand-Gaday , Laurence Pessemesse , Barbara Vernus et al.

Bioblast 2022: BEC Inaugural Conference, Carolina Gnaiger; Verena Laner, Jun 2022, Innsbruck, Austria. https://doi.org/10.26124/bec:2022-0001

Communication dans un congrès hal-04233589v1

A single short reprogramming early in life improves fitness and increases lifespan in old age

Quentin Alle , Enora Le Borgne , Paul Bensadoun , Camille Lemey , Nelly Bechir et al.

2. Euro Geroscience Conference, Mar 2022, Toulouse, France

Communication dans un congrès hal-04902975v1

Salidroside supplementation associated with intermittent exercise enhances physical performance in old mice

Rémi Roumanille , Thomas Brioche , Théo Fovet , Corentin Guilhot , Pierre Delobel et al.

10. International Conference on Frailty, Sarcopenia Research and Geroscience (ICFSR), Mar 2020, Toulouse, France. pp.26-26, ⟨10.14283/jfa.2020.8⟩

Communication dans un congrès hal-04939000v1
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eIF3f depletion impedes mouse embryonic development, reduces adult skeletal muscle mass and amplifies muscle loss during disuse

Aurélie Docquier , Laura Pavlin , Audrey Raibon , Christelle Bertrand , Chamroeun Sar et al.

5. International Congress of Translational Research in Human Nutrition (ICTRNH 2019), Jun 2019, Clermont-Ferrand, France

Communication dans un congrès hal-02737500v1

Rhaponticum carthamoides and Rhodiola rosea plant extracts: the right combination between both to get the optimal effect on muscle de novo protein synthesis and performance gain

Pascale Fanca-Berthon , Sarah Campredon , Guillaume Py , Vincent Descossy , Christophe Tran van Ba et al.

Annual Meeting of the American-Society-for-Pharmacology-and-Experimental-Therapeutics (ASPET), Apr 2017, Chicago, United States

Communication dans un congrès hal-01607503v1

Effect of fluoxetine on neuromuscular function in acetylcholinesterase (AChE) knockout mice

Christelle Bertrand , Béatrice Bonafos , Maud Tremblay , Arnaud Ferry , Arnaud Chatonnet

9. International Meeting on Cholinesterases, May 2007, Suzhou, China. ⟨10.1016/j.cbi.2008.04.002⟩

Communication dans un congrès istex hal-02758520v1

Genetic ablation of acetylcholinesterase alters muscle function in mice

Audrey Vignaud , F. Fougerousse , E. Mouisel , Christelle Bertrand , Béatrice Bonafos et al.

9. International Meeting on Cholinesterases, May 2007, Suzhou, China. ⟨10.1016/j.cbi.2008.04.035⟩

Communication dans un congrès istex hal-02758076v1

Effect of fluoxetine on neuromuscular function in acetylcholinesterase (AChe) knockout mice

Arnaud Chatonnet , Christelle Bertrand , Laurence Lepourry , Nathalie Barougier , Anne Ferry

9.International Meeting on Cholinesterases, May 2007, Suzhou, China. n.p

Communication dans un congrès hal-02823585v1

Acetylcholinesterase expression during development of danio rerio

Christelle Bertrand , Xavier Cousin , J.P. Toutant , Arnaud Chatonnet

6. International Meeting on Cholinesterases, Mar 1998, La Jolla, California, United States

Communication dans un congrès hal-02767015v1

L'acétylcholinestérase des poissons, cible des organophosphorés et des carbamates. Caractérisation du gène et des formes moléculaires de l'enzyme chez Danio rerio. Effets des anticholinestérasiques

Christelle Bertrand , Xavier Cousin , E. Haubruge , J.P. Toutant , Arnaud Chatonnet

Facteurs de l'environnement et biologie des poissons, Sep 1997, Rennes, France

Communication dans un congrès hal-02839645v1

L'acide gras furanique extrait du latex d'Hevea brasiliensis augmente la masse musculaire chez la souris

François Pelletier , Erwann Durand , Laurence Pessemesse , Laurent Vaysse , Siriluck Liengprayoon et al.

Journées Francophones de Nutrition (JFN 2023), Dec 2023, Marseille, France.

Poster de conférence hal-04849389v1

Furan fatty acid supplementation reverses the development of some cardiometabolic disorders in obese mice

Mathys Chaslin , Erwann Durand , Béatrice Bonafos , Jatuporn Chaiyut , Laurent Vaysse et al.

Journées Francophones de Nutrition (JFN 2022), Nov 2022, Toulouse, France

Poster de conférence hal-04849353v1
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Rôle du microbiote dans la relation entre activité physique, santé et bien-être

Benedicte Goustard , Barbara Vernus , Olivier Rué , Mahendra Mariadassou , Laurence Pessemesse et al.

Journées d'Animation Scientifiques du Département PHASE, May 2022, Poitiers, France. 317, pp.E158 - E171

Poster de conférence hal-04804882v1

Butyrylcholinesterase and Ghrelin in the Myostatin knock-out mouse. Impact on stress, aggressivity and behavior

Barbara Vernus , Benedicte Goustard , Ariane Migeon , Lucie Ducornet , Christelle Bertrand-Gaday et al.

14. International Meeting on Cholinesterases / 8. Conference on Paraoxonase, Sep 2022, Bologna, Italy

Poster de conférence hal-04816235v1

Interaction Ghréline-Myostatine-Butyrylcholinestérase dans le métabolisme musculaire et le comportement.

Barbara Vernus , Benedicte Goustard , Ariane Migeon , Lucie Ducornet , Christelle Bertrand-Gaday et al.

Journées d'Animation Scientifiques du Département PHASE, May 2022, Poitiers, France

Poster de conférence hal-04818883v1
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Des changements transitoires du métabolisme du zygote chez la souris influencent le phénotype musculaire à l'âge adulte

Christelle Bertrand-Gaday , Martine Letheule , Emilie Blanchet , Barbara Vernus , Laurence Pessemesse et al.

Journées d'Animation Scientifiques du Département PHASE, May 2022, Poitiers, France. 21, 2020, ⟨10.3390/ijms21197203⟩

Poster de conférence hal-04816250v1

Salidroside supplementation associated with resistance exercise enhances physical performance in old mice

Rémi Roumanille , Guillaume Py , Thomas Brioche , Angèle Chopard , Anne Bonnieu et al.

3. Congress of Physiology and Integrative Biology (CPBI) and 86. Congress of French Physiological Society (SFP), Jun 2019, Montpellier, France. WILEY, Acta Physiologica, 227 (Supp 720), 2019, Abstracts of the 3rd Congress of Physiology and Integrative Biology (CPBI) and 86th Congress of French Physiological Society (SFP)

Poster de conférence hal-02734715v1

Impact du statut énergétique de l’œuf sur deux modèles génétiques d’hypertrophie musculaire

Christelle Bertrand , Emilie Blanchet , Barbara Vernus , Bernadette Banrezes , Anne Bonnieu et al.

Journées d’Animation des Crédits Incitatifs du Département de Physiologie Animale et Systèmes d’Elevage (JACI Phase 2016), Apr 2016, Tours, France. , 115 p., 2016, Crédits Incitatifs financés entre 2011 et 2014

Poster de conférence hal-01837627v1