christophe lachaud

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Documents

Présentation

CRCM - Cancer research centre of Marseille (AMU, CRNS, INSERM, Institut Paoli-Calmettes

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Publications

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Alkyne modification of DNA cross-linking antitumor agent SJG-136 to monitor induced lesions in cells by click chemistry

Sara Berrada , Violette Azzoni , Gilles Audoly , Lara Lee , Jean-Hugues Guervilly et al.

Chemico-Biological Interactions, 2025, pp.111846. ⟨10.1016/j.cbi.2025.111846⟩

Article dans une revue hal-05392822v1
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TERT expression attenuates metabolic disorders in obese mice by promoting adipose stem and progenitor cell expansion and differentiation

Laura Braud , Manuel Bernabe , Julien Vernerey , Antonio M A Miranda , Andrea Dominguez et al.

Molecular metabolism, 2025, 102, pp.102262. ⟨10.1016/j.molmet.2025.102262⟩

Article dans une revue hal-05392957v1
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Inhibition of the STAT3/Fanconi anemia axis is synthetic lethal with PARP inhibition in breast cancer

Celia D Rouault , Lucile Bansard , Elena Martínez-Balsalobre , Caroline Bonnet , Julien Wicinski et al.

Nature Communications, 2025, 16 (1), pp.2159. ⟨10.1038/s41467-025-57476-4⟩

Article dans une revue hal-04979265v1
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mTert induction in p21-positive cells counteracts capillary rarefaction and pulmonary emphysema

Larissa Lipskaia , Marielle Breau , Christelle Cayrou , Dmitri Churikov , Laura Braud et al.

EMBO Reports, 2024, 25 (3), pp.1650-1684. ⟨10.1038/s44319-023-00041-1⟩

Article dans une revue hal-04780086v1
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STIM1 translocation to the nucleus protects cells from DNA damage

Irene Sanchez-Lopez , Yolanda Orantos-Aguilera , Eulalia Pozo-Guisado , Alberto Alvarez-Barrientos , Sergio Lilla et al.

Nucleic Acids Research, 2024, 52 (5), pp.2389 - 2415. ⟨10.1093/nar/gkae001⟩

Article dans une revue hal-04780091v1
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mTert induction in p21-positive cells counteracts capillary rarefaction and pulmonary emphysema

Larissa Lipskaia , Marielle Breau , Christelle Cayrou , Dmitri Churikov , Laura Braud et al.

EMBO Reports, 2024, 25, pp.1650 - 1684. ⟨10.1038/s44319-023-00041-1⟩

Article dans une revue hal-05392968v1
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Heterozygous<i>RPA2</i>variant as a novel genetic cause of telomere biology disorders

Rima Kochman , Ibrahima Ba , Maïlyn Yates , Vithura Pirabakaran , Florian Gourmelon et al.

Genes and Development, 2024, ⟨10.1101/gad.352032.124⟩

Article dans une revue hal-05392974v1
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Current and future perspectives of Fanconi Anemia treatment

Elena Martínez-Balsalobre , Jean-Hugues Guervilly , Ana Belen Pérez-Oliva , Jenny van Asbeck-van der Wijst , Lachaud Christophe

Blood Reviews, 2023, 6, pp.1. ⟨10.1186/1877-6566-6-1⟩

Article dans une revue (article de synthèse) hal-04260951v1
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ZAKα / P38 kinase signaling pathway regulates hematopoiesis by activating the NLRP1 inflammasome

Lola Rodríguez‐ruiz , Juan M Lozano‐gil , Elena Naranjo‐sánchez , Elena Martínez‐balsalobre , Alicia Martínez-López et al.

EMBO Molecular Medicine, 2023, 15 (10), ⟨10.15252/emmm.202318142⟩

Article dans une revue hal-04275199v1
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ZAKα/P38 kinase signaling pathway regulates hematopoiesis by activating the NLRP1 inflammasome

Lola Rodríguez‐ruiz , Juan M Lozano‐gil , Elena Naranjo‐sánchez , Elena Martínez‐balsalobre , Alicia Martínez‐lópez et al.

EMBO Molecular Medicine, 2023, 15 (10), ⟨10.15252/emmm.202318142⟩

Article dans une revue hal-04780099v1
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A clickable melphalan for monitoring DNA interstrand crosslink accumulation and detecting ICL repair defects in Fanconi anemia patient cells

Sara Berrada , Elena Martínez-Balsalobre , Lise Larcher , Violette Azzoni , Nadia Vasquez et al.

Nucleic Acids Research, 2023, 51 (15), pp.7988 - 8004. ⟨10.1093/nar/gkad559⟩

Article dans une revue hal-04275209v1
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UFMylation of MRE11 is essential for telomere length maintenance and hematopoietic stem cell survival

Lara Lee , Ana Belen Perez Oliva , Elena Martinez-Balsalobre , Dmitri Churikov , Joshua Peter et al.

Science Advances , 2021, 7 (39), ⟨10.1126/sciadv.abc7371⟩

Article dans une revue hal-03375722v1

UFMylation of MRE11 is essential for telomere length maintenance and hematopoietic stem cell survival

Lara Lee , Ana Belen Perez Oliva , Elena Martinez-Balsalobre , Dmitri Churikov , Joshua Peter et al.

Science Advances , 2021, 7 (39), ⟨10.1126/sciadv.abc7371⟩

Article dans une revue hal-03622430v1
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Zebrafish Models to Study Inflammasome-Mediated Regulation of Hematopoiesis

Lola Rodríguez-Ruiz , Juan Lozano-Gil , Christophe Lachaud , Pablo Mesa-Del-Castillo , María Cayuela et al.

Current Trends in Immunology, 2020, ⟨10.1016/j.it.2020.10.006⟩

Article dans une revue hal-03020978v1
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Inflammasome Regulates Hematopoiesis through Cleavage of the Master Erythroid Transcription Factor GATA1

Sylwia D Tyrkalska , Ana B Pérez-Oliva , Lola Rodríguez-Ruiz , Francisco J Martínez-Morcillo , Francisca Alcaraz-Pérez et al.

Immunity, 2019, Epub ahead of print. ⟨10.1016/j.immuni.2019.05.005⟩

Article dans une revue hal-02148333v1

Lipo-chitooligosaccharidic Symbiotic Signals Are Recognized by LysM Receptor-Like Kinase LYR3 in the Legume Medicago truncatula.

Judith Fliegmann , Sophie Canova , Christophe Lachaud , Sandra Uhlenbroich , Virginie Gasciolli et al.

ACS Chemical Biology, 2013, 8 (9), pp.1900-1906. ⟨10.1021/cb400369u⟩

Article dans une revue hal-00856771v1

Nuclear calcium controls the apoptotic-like cell death induced by d-erythro-sphinganine in tobacco cells

Christophe Lachaud , Daniel da Silva , Valérie Cotelle , Patrice Thuleau , Tou Cheu Xiong et al.

Cell Calcium, 2010, 47 (1), pp.92-100. ⟨10.1016/j.ceca.2009.11.011⟩

Article dans une revue istex hal-01203919v1

Remarkable Influence of molecular structure of N,N'-unsymmetrically substituted 1,3-amidinate and -guanidinate on the Volatility and the Thermal Stability of Precursors for HfO2 Films via Liquid Injection-MOCVD

Mohamad Eleter , Stephane Daniele , Virginie Brize , Catherine Dubourdieu , Christophe Lachaud et al.

ECS Transactions, 2009, 25 (8), pp.151-158. ⟨10.1149/1.3207586⟩

Article dans une revue hal-01067593v1