Clement Mettling

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Publications

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Perceptual Advantages of People Living in Semeru Volcanic Areas, Indonesia: An MRCV (Multiple Response Categorical Variable) Analysis

Yanti Ariyanti , Sarah Nila , Winati Nurhayu , Dimitri Dubois , Kanthi Arum Widayati et al.

HAYATI Journal of Biosciences, 2026, 33 (3), pp.739-749. ⟨10.4308/hjb.33.3.739-749⟩

Article dans une revue hal-05492915v1
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γ-Aminobutyric Acid-Induced Monocytic Reactive Oxygen Species Impair CD4 Restoration in Treated Adults With HIV-1

Mehwish Younas , Sandrine Gimenez , Yea-Lih Lin , Clément Mettling , Domenico Maiorano et al.

Journal of Infectious Diseases, In press, pp.jiaf058. ⟨10.1093/infdis/jiaf058⟩

Article dans une revue hal-05057438v1
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Low Percentage of Perforin-Expressing NK Cells during Severe SARS-CoV-2 Infection: Consumption Rather than Primary Deficiency

Lucy Kundura , Renaud Cezar , Emma Ballongue , Sonia André , Moïse Michel et al.

Journal of Immunology, 2024, 212 (7), pp.1105 - 1112. ⟨10.4049/jimmunol.2300359⟩

Article dans une revue hal-04748173v1
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The EBI2 receptor is coexpressed with CCR5 in CD4+ T cells and boosts HIV-1 R5 replication

Adeline Guigues , Sandrine Gimenez , Clément Mettling , Damien Maurel , Etienne Doumazane et al.

AIDS. Official journal of the international AIDS Society, 2024, 38 (10), pp.1449-1459. ⟨10.1097/QAD.0000000000003931⟩

Article dans une revue hal-04748558v1
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MRE11 and TREX1 control senescence by coordinating replication stress and interferon signaling

Hervé Técher , Diyavarshini Gopaul , Jonathan Heuzé , Nail Bouzalmad , Baptiste Leray et al.

Nature Communications, 2024, 15 (1), pp.5423. ⟨10.1038/s41467-024-49740-w⟩

Article dans une revue hal-04748159v1
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A Tripartite Complex HIV-1 Tat-Cyclophilin A-Capsid Protein Enables Tat Encapsidation That Is Required for HIV-1 Infectivity

Malvina Schatz , Laetitia Marty , Camille Ounadjela , Phuoc Bao Viet Tong , Ilaria Cardace et al.

Journal of Virology, 2023, 97 (4), ⟨10.1128/jvi.00278-23⟩

Article dans une revue hal-04106774v1
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The effect of the 7R allele at the DRD4 locus on risk tolerance is independent of background risk in Senegalese fishermen

Gwen-Jirō Clochard , Aby Mbengue , Clément Mettling , Birane Diouf , Charlotte Faurie et al.

Scientific Reports, 2023, 13 (1), pp.622. ⟨10.1038/s41598-022-27002-3⟩

Article dans une revue hal-03954770v1
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Angiotensin II induces reactive oxygen species, DNA damage, and T-cell apoptosis in severe COVID-19

Lucy Kundura , Sandrine Gimenez , Renaud Cezar , Sonia André , Mehwish Younas et al.

Journal of Allergy and Clinical Immunology, 2022, 150 (3), pp.594-603.e2. ⟨10.1016/j.jaci.2022.06.020⟩

Article dans une revue hal-03837641v1

SAMHD1 agit sur les fourches de réplication bloquées pour empêcher l’induction d’interféron

F. Coquel , M. Silva , H. Técher , K. Zadorozhny , S. Sharma et al.

Comptes Rendus. Biologies, 2020, 343 (1), pp.9-21. ⟨10.5802/crbiol.10⟩

Article dans une revue hal-03078628v1
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SAMHD1 agit sur les fourches de réplication bloquées pour empêcher l’induction d’interféron

F. Coquel , M. Silva , H. Técher , K. Zadorozhny , S. Sharma et al.

Comptes Rendus. Biologies, 2020, 343 (1), pp.9-21. ⟨10.5802/crbiol.10⟩

Article dans une revue hal-03083188v1
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Topoisomerase 1 prevents replication stress at R-loop-enriched transcription termination sites

Alexy Promonet , Ismaël Padioleau , Yaqun Liu , Lionel A. Sanz , Anna Biernacka et al.

Nature Communications, 2020, 11 (1), ⟨10.1038/s41467-020-17858-2⟩

Article dans une revue hal-02931000v1
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Genomic amplification of chromosome 20q13.33 is the early biomarker for the development of sporadic colorectal carcinoma

Vo-Minh-Hoang Bui , Clément Mettling , Jonathan Jou , H Sunny Sun

BMC Medical Genomics, 2020, 13, ⟨10.1186/s12920-020-00776-z⟩

Article dans une revue hal-03078496v1
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Cyclophilin A enables specific HIV-1 Tat palmitoylation and accumulation in uninfected cells

Christophe Chopard , Phuoc Bao Viet Tong , Petra Toth , Malvina Schatz , Hocine Yezid et al.

Nature Communications, 2018, 9 (1), pp.2251. ⟨10.1038/s41467-018-04674-y⟩

Article dans une revue hal-02146273v1

Reversing HIV latency via sphingosine-1-phosphate receptor 1 signaling

Charline Duquenne , Sandrine Gimenez , Adeline Guigues , Benjamin Viala , Caroline Boulouis et al.

AIDS. Official journal of the international AIDS Society, 2017, 31 (18), pp.2443 - 2454. ⟨10.1097/QAD.0000000000001649⟩

Article dans une revue hal-01635726v1
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Autophagy-associated dengue vesicles promote viral transmission avoiding antibody neutralization

Yw Wu , C Mettling , Sr Wu , Cy Yu , Gc Perng et al.

Scientific Reports, 2016, 6, pp.32243. ⟨10.1038/srep32243⟩

Article dans une revue hal-01377127v1
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Evidence of genotypic adaptation to the exposure to volcanic risk at the dopamine receptor DRD4 locus

Charlotte Faurie , Clement Mettling , Mohamed Ali Bchir , Danang Hadmoko , Carine Heitz et al.

Scientific Reports, 2016, 6 (37745), 7 p. ⟨10.1038/srep37745⟩

Article dans une revue hal-02062364v1
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HIV-1 Tat inhibits phagocytosis by preventing the recruitment of Cdc42 to the phagocytic cup

Solène Debaisieux , Simon Lachambre , Antoine Gross , Clément Mettling , Sébastien Besteiro et al.

Nature Communications, 2015, 6 (1), pp.6211. ⟨10.1038/ncomms7211⟩

Article dans une revue hal-02146268v1

The Two Human CXCR4 Isoforms Display Different HIV Receptor Activities: Consequences for the Emergence of X4 Strains

C Duquenne , C Psomas , S Gimenez , A Guigues , Mj Carles et al.

Journal of Immunology, 2014, 193 (8), pp.4188-4194. ⟨10.4049/jimmunol.1303298⟩

Article dans une revue hal-01074809v1
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Combined Phytochemistry and Chemotaxis Assays for Identification and Mechanistic Analysis of Anti-Inflammatory Phytochemicals in Fallopia japonica

Ming-Yi Shen , Yan-Jun Liu , Ming-Jaw Don , Hsien-Yueh Liu , Zeng-Weng Chen et al.

PLoS ONE, 2011, 6 (11), pp.e27480. ⟨10.1371/journal.pone.0027480⟩

Article dans une revue hal-00645719v1

Strategy for anti-aquaporin-4 auto-antibody identification and quantification using a new cell-based assay

I. de Vidi , G. Boursier , N. Delouche , P. Portales , E. Cadars et al.

Clinical Immunology, 2011, 138 (3), pp.239-246. ⟨10.1016/j.clim.2010.11.012⟩

Article dans une revue istex hal-00575112v1
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Phosphatidylinositol-(4,5)-bisphosphate enables efficient secretion of HIV-1 Tat by infected T-cells

Fabienne Rayne , Solène Debaisieux , Hocine Yezid , Yea-Lih Lin , Clément Mettling et al.

EMBO Journal, 2010, 29 (8), pp.1348-1362. ⟨10.1038/emboj.2010.32⟩

Article dans une revue hal-02147182v1

The chemokine CCL5 regulates the in vivo cel surface of its receptor, CCR5

Yea-Lih Lin , C. Mettling , P. Portales , Roman Rouzier , J. Clot et al.

AIDS. Official journal of the international AIDS Society, 2008, 22 (3), pp.430-432. ⟨10.1097/QAD.0b013e3282f46a6f⟩

Article dans une revue hal-00206135v1

Galphai protein-dependant extracellular signal-regulated kinase-1/2 activation is required for HIV-1 reverse transcription

C. Mettling , C. Desmetz , Al Fiser , B. Reant , P. Corbeau et al.

AIDS. Official journal of the international AIDS Society, 2008, 13, pp.1569-1576. ⟨10.1097/QAD.0b013e32830abdaf⟩

Article dans une revue hal-00322412v1

Suv39H1 and HP1**g** are responsible for chromatin-mediated HIV-1 transcriptional silencing and post integration latency.

I. Du Chene , E. Basyuk , Yea-Lih Lin , R. Triboulet , A. Knezevich et al.

EMBO Journal, 2007, 26 (2), pp.424-435. ⟨10.1038/sj.emboj.7601517⟩

Article dans une revue hal-00130455v1

Small-molecule inhibition of HIV pre-mRNA splicing as a novel antiretroviral therapy to overcome drug resistance

N. Bakkour , Yl. Lin , S. Maire , L. Ayadi , Florence Mahuteau-Betzer et al.

PLoS Pathogens, 2007, 3 (10), pp.1530-1539. ⟨10.1371/journal.ppat.0030159⟩

Article dans une revue hal-00259118v1
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Small-molecule inhibition of HIV pre-mRNA splicing as a novel antiretroviral therapy to overcome drug resistance

N. Bakkour , Yea-Lih Lin , S. Maire , L. Ayadi , Florence Mahuteau-Betzer et al.

PLoS Pathogens, 2007, 3 (10), pp.e159. ⟨10.1371/journal.ppat.0030159⟩

Article dans une revue hal-00185296v1

Cell surface CCR5 density determines the intensity of T cell migration towards rheumatoid arthritis synoviocytes.

C. Desmetz , Yea-Lih Lin , C. Mettling , P. Portales , D. Noel et al.

Clinical Immunology, 2007, 123 (2), pp.148-154. ⟨10.1016/j.clim.2007.01.004⟩

Article dans une revue istex hal-00148014v1
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Unintegrated HIV-1 provides an inducible and functional reservoir in untreated and highly active antiretroviral therapy-treated patients

G. Petitjean , Y. Al Tabaa , E. Tuaillon , C. Mettling , V. Baillat et al.

Retrovirology, 2007, 4, pp.60. ⟨10.1186/1742-4690-4-60⟩

Article dans une revue hal-00194043v1

The efficiency of R5 HIV-1 infection is determined by CD4 T-cell surface CCR5 density through Galphai-protein signalling

Yea-Lih Lin , C. Mettling , P. Portales , B. Reant , V. Robert-Hebmann et al.

AIDS. Official journal of the international AIDS Society, 2006, 20, pp.1369-1377. ⟨10.1097/01.aids.0000233570.51899.e2⟩

Article dans une revue hal-00082331v1

The strength of the chemotactic response to a CCR5 binding chemokine is determined by the level of cell surface CCR5 density.

C. Desmetz , Yea-Lih Lin , C. Mettling , P. Portales , H. Rabesandratana et al.

Immunology, 2006, 119 (4), pp.551-561. ⟨10.1111/j.1365-2567.2006.02470.x⟩

Article dans une revue hal-00122082v1

Structure-based design, synthesis, and biological evaluation of novel inhibitors of human cyclophilin A.

Jf Guichou , J. Viaud , C. Mettling , G. Subra , Yea-Lih Lin et al.

Journal of Medicinal Chemistry, 2006, 49 (3), pp.900-910. ⟨10.1021/jm050716a⟩

Article dans une revue hal-00113407v1

Effects of virion surface gp120 density on infection by HIV-1 and viral production by infected cells

E. Bachrach , H. Dreja , Y. L. Lin , C. Mettling , V. Pinet et al.

Virology, 2005, 332 (1), pp.418--29. ⟨10.1016/j.virol.2004.11.031⟩

Article dans une revue hal-02262222v1
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Inhibition of PrPSc formation by lentiviral gene transfer of PrP containing dominant negative mutations.

Carole Crozet , Yea-Lih Lin , Clément Mettling , Chantal Mourton-Gilles , Pierre Corbeau et al.

Journal of Cell Science, 2004, 117 (Pt 23), pp.5591-7. ⟨10.1242/jcs.01484⟩

Article dans une revue inserm-00143203v1

Regulatory elements and interactions in theDrosophila 68C glue gene cluster

Marianne Martin , Clément Mettling , Angela Giangrande , Claude Ruiz , Geoff Richards

Developmental Genetics, 1989, 10 (3), pp.189-197. ⟨10.1002/dvg.1020100308⟩

Article dans une revue istex hal-03478180v1

Drosophila Sgs3 TATA: effects of point mutations on expression in vivo and protein binding in vitro with staged nuclear extracts.

A Giangrande , C Mettling , M Martin , C Ruiz , G Richards

EMBO Journal, 1989, 8 (11), pp.3459-66

Article dans une revue hal-03478183v1

The use of oligonucleotide probes in studies of insect gene activity in development

Clément Mettling , Angela Giangrande , Geoff Richards

Journal of Insect Physiology, 1988, 34 (7), pp.679-684. ⟨10.1016/0022-1910(88)90077-7⟩

Article dans une revue istex hal-03478161v1

Sps-3 transcript levels are determined by multiple remote sequence elements.

A Giangrande , C Mettling , G Richards

EMBO Journal, 1987, 6 (10), pp.3079-84

Article dans une revue hal-03475626v1

The Drosophila sgs3 gene: an in-vivo test of intron function

Clément Mettling , Angela Giangrande , Geoff Richards

Journal of Molecular Biology, 1987, 196 (1), pp.223-226. ⟨10.1016/0022-2836(87)90523-7⟩

Article dans une revue istex hal-03475625v1