| 
        
                            
                    
     | 
        
        
            Conformational diversity in class C GPCR positive allosteric modulation
        
                            
                                                                                                            Giuseppe Cannone
                                                                ,
                                                                                                                                Ludovic Berto
                                                                ,
                                                                                                                                Fanny Malhaire
                                                                ,
                                                                                                                                Gavin Ferguson
                                                                ,
                                                                                                                                Aurelien Fouillen
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-04889109
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     | 
        
        
            Bistable and Water‐Operable Hemiindigo Photoswitches Allow Optical Control of Acetylcholinesterase Activity with Visible Light
        
                            
                                                                                                            Letícia da Mata Lazinski
                                                                ,
                                                                                                                                Morane Beaumet
                                                                ,
                                                                                                                                Frédérique Loiseau
                                                                ,
                                                                                                                                Cyril Goudet
                                                                ,
                                                                                                                                Martial Boggio‐pasqua
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-05339073
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     | 
        
        
            A photoswitchable positive allosteric modulator to control the activation of the metabotropic glutamate receptor 5 by light
        
                            
                                                                                                            Anaëlle Dumazer
                                                                ,
                                                                                                                                Roser Borras-Tuduri
                                                                ,
                                                                                                                                Iona Truong
                                                                ,
                                                                                                                                Xiaojing Cong
                                                                ,
                                                                                                                                Fanny Malhaire
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-05140566
                                            v1
                                    
            
        
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     | 
        
        
            Optical Control of Adenosine A 2A Receptor Using Istradefylline Photosensitivity
        
                            
                                                                                                            Anaëlle Dumazer
                                                                ,
                                                                                                                                Xavier Gómez-Santacana
                                                                ,
                                                                                                                                Fanny Malhaire
                                                                ,
                                                                                                                                Chris Jopling
                                                                ,
                                                                                                                                Damien Maurel
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-04425630
                                            v1
                                    
            
        
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    | 
        
                            
                    
     | 
        
        
            A ‘double-edged’ role for type-5 metabotropic glutamate receptors in pain disclosed by light-sensitive drugs
        
                            
                                                                                                            Serena Notartomaso
                                                                ,
                                                                                                                                Nico Antenucci
                                                                ,
                                                                                                                                Mariacristina Mazzitelli
                                                                ,
                                                                                                                                Xavier Rovira
                                                                ,
                                                                                                                                Serena Boccella
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-04676043
                                            v1
                                    
            
        
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     | 
        
        
            Novel Inhibitory Site Revealed by XAP044 Mode of Action on the Metabotropic Glutamate 7 Receptor Venus Flytrap Domain
        
                            
                                                                                                            Nunzia Cristiano
                                                                ,
                                                                                                                                Alexandre Cabayé
                                                                ,
                                                                                                                                Isabelle Brabet
                                                                ,
                                                                                                                                Ralf Glatthar
                                                                ,
                                                                                                                                Amelie Tora
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                 Article dans une revue
                    
        
        
            
                
                    hal-04569147
                                            v1
                                    
            
        
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     | 
        
        
            Photoswitchable positive allosteric modulators of metabotropic glutamate receptor 4 to improve selectivity
        
                            
                                                                                                            Silvia Panarello
                                                                ,
                                                                                                                                Aleix González-Díez
                                                                ,
                                                                                                                                Alice E Berizzi
                                                                ,
                                                                                                                                Fanny Malhaire
                                                                ,
                                                                                                                                Roser Borràs-Tudurí
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-04609139
                                            v1
                                    
            
        
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     | 
        
        
            The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors
        
                            
                                                                                                            Stephen Alexander
                                                                ,
                                                                                                                                Arthur Christopoulos
                                                                ,
                                                                                                                                Anthony Davenport
                                                                ,
                                                                                                                                Eamonn Kelly
                                                                ,
                                                                                                                                Alistair Mathie
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-04858591
                                            v1
                                    
            
        
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    | 
        
                            
                    
     | 
        
        
            Photopharmacological manipulation of amygdala metabotropic glutamate receptor mGlu4 alleviates neuropathic pain
        
                            
                                                                                                            Vanessa Pereira
                                                                ,
                                                                                                                                Juri Aparicio Arias
                                                                ,
                                                                                                                                Amadeu Llebaria
                                                                ,
                                                                                                                                Cyril Goudet
                                                                                    
                 
                            
                 Article dans une revue
                             (data paper)
                    
        
        
            
                
                    hal-03914258
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Editorial: Molecular mechanisms of nociception
        
                            
                                                                                                            Cyril Goudet
                                                                ,
                                                                                                                                Fabien Marchand
                                                                                    
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03805607
                                            v1
                                    
            
        
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    | 
        
                            
                    
     | 
        
        
            International Union of Basic and Clinical Pharmacology. CXI. Pharmacology, Signaling, and Physiology of Metabotropic Glutamate Receptors
        
                            
                                                                                                            Karen J Gregory
                                                                ,
                                                                                                                                Cyril Goudet
                                                                                    
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03099669
                                            v1
                                    
            
        
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    | 
        
                                                 
                        
                     
                                    
     | 
        
        
            THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein‐coupled receptors
        
                            
                                                                                                            Stephen Alexander
                                                                ,
                                                                                                                                Arthur Christopoulos
                                                                ,
                                                                                                                                Anthony Davenport
                                                                ,
                                                                                                                                Eamonn Kelly
                                                                ,
                                                                                                                                Alistair Mathie
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03875300
                                            v1
                                    
            
        
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    | 
        
                            
                    
     | 
        
        
            Les avancées récentes dans le domaine de la biologie structurale des récepteurs couplés aux protéines G de la classe C : Le récepteur métabotropique du glutamate 5
        
                            
                                                                                                            Ludovic Berto
                                                                ,
                                                                                                                                Anaëlle Dumazer
                                                                ,
                                                                                                                                Fanny Malhaire
                                                                ,
                                                                                                                                Giuseppe Cannone
                                                                ,
                                                                                                                                Vinothkumar Kutti
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03744975
                                            v2
                                    
            
        
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    | 
        
                            
                    
     | 
        
        
            Agonists and allosteric modulators promote signaling from different metabotropic glutamate receptor 5 conformations
        
                            
                                                                                                            Chady Nasrallah
                                                                ,
                                                                                                                                Giuseppe Cannone
                                                                ,
                                                                                                                                Julie Briot
                                                                ,
                                                                                                                                Karine Rottier
                                                                ,
                                                                                                                                Alice Berizzi
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03340751
                                            v1
                                    
            
        
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     | 
        
        
            Mechanistic insights into light-driven allosteric control of GPCR biological activity
        
                            
                                                                                                            Maria Ricart-Ortega
                                                                ,
                                                                                                                                Alice Berizzi
                                                                ,
                                                                                                                                Vanessa Pereira
                                                                ,
                                                                                                                                Fanny Malhaire
                                                                ,
                                                                                                                                Juanlo Catena
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-02924800
                                            v1
                                    
            
        
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            Development and validation of a mass spectrometry binding assay for mGlu5 receptor
        
                            
                                                                                                            Maria Ricart-Ortega
                                                                ,
                                                                                                                                Alice Berizzi
                                                                ,
                                                                                                                                Juanlo Catena
                                                                ,
                                                                                                                                Fanny Malhaire
                                                                ,
                                                                                                                                Lourdes Muñoz
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-02884945
                                            v1
                                    
            
        
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    | 
        
                            
                    
     | 
        
        
            THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: G protein‐coupled receptors
        
                            
                                                                                                            Stephen Alexander
                                                                ,
                                                                                                                                Arthur Christopoulos
                                                                ,
                                                                                                                                Anthony P Davenport
                                                                ,
                                                                                                                                Eamonn Kelly
                                                                ,
                                                                                                                                Alistair Mathie
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-02388696
                                            v1
                                    
            
        
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    | 
        
                            
                    
     | 
        
        
            Emerging Trends in Pain Modulation by Metabotropic Glutamate Receptors
        
                            
                                                                                                            Vanessa Pereira
                                                                ,
                                                                                                                                Cyril Goudet
                                                                                    
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-02388671
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Dynamic modulation of inflammatory pain-related affective and sensory symptoms by optical control of amygdala metabotropic glutamate receptor 4
        
                            
                                                                                                            Charleine Zussy
                                                                ,
                                                                                                                                X. Gomez-Santacana
                                                                ,
                                                                                                                                Xavier Rovira
                                                                ,
                                                                                                                                Dimitri de Bundel
                                                                ,
                                                                                                                                S. Ferrazzo
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-02073218
                                            v1
                                    
            
        
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    | 
        
                            
                    
     | 
        
        
            Shedding light on metabotropic glutamate receptors using optogenetics and photopharmacology
        
                            
                                                                                                            Cyril Goudet
                                                                ,
                                                                                                                                Xavier Rovira
                                                                ,
                                                                                                                                Amadeu Llebaria
                                                                                    
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-02388700
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                                                
     | 
        
        
            Profiling of orthosteric and allosteric group-III metabotropic glutamate receptor ligands on various G protein-coupled receptors with Tag-lite® assays
        
                            
                                                                                                            Abderazak Belhocine
                                                                ,
                                                                                                                                Pietro Veglianese
                                                                ,
                                                                                                                                Candide Hounsou
                                                                ,
                                                                                                                                Elodie Dupuis
                                                                ,
                                                                                                                                Francine C. Acher
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-02388698
                                            v1
                                    
            
        
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    | 
        
                                                
     | 
        
        
            Increased Potency and Selectivity for Group III Metabotropic Glutamate Receptor Agonists Binding at Dual sites
        
                            
                                                                                                            Chelliah Selvam
                                                                ,
                                                                                                                                Isabelle Lemasson
                                                                ,
                                                                                                                                Isabelle Brabet
                                                                ,
                                                                                                                                Nadia Oueslati
                                                                ,
                                                                                                                                Berin Karaman
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-02018007
                                            v1
                                    
            
        
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    | 
        
                            
                    
     | 
        
        
            Chloride ions stabilize the glutamate-induced active state of the metabotropic glutamate receptor 3
        
                            
                                                                                                            Amélie S. Tora
                                                                ,
                                                                                                                                Xavier Rovira
                                                                ,
                                                                                                                                Anne-Marinette Cao
                                                                ,
                                                                                                                                Alexandre Cabaye
                                                                ,
                                                                                                                                Linnea Olofsson
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-02346230
                                            v1
                                    
            
        
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            Optical control of pain in vivo with a photoactive mGlu5 receptor negative allosteric modulator
        
                            
                                                                                                            Joan Font
                                                                ,
                                                                                                                                Marc López-Cano
                                                                ,
                                                                                                                                Serena Notartomaso
                                                                ,
                                                                                                                                Pamela Scarselli
                                                                ,
                                                                                                                                Paola Di Pietro
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03549950
                                            v1
                                    
            
        
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     | 
        
        
            Allosteric control of an asymmetric transduction in a G protein-coupled receptor heterodimer
        
                            
                                                                                                            Junke Liu
                                                                ,
                                                                                                                                Zongyong Zhang
                                                                ,
                                                                                                                                David Moreno-Delgado
                                                                ,
                                                                                                                                James Ar Dalton
                                                                ,
                                                                                                                                Xavier Rovira
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-02073040
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                                                 
                        
                     
                                    
     | 
        
        
            Positional isomers of bispyridine benzene derivatives induce efficacy changes on mGlu 5 negative allosteric modulation
        
                            
                                                                                                            Xavier Gómez-Santacana
                                                                ,
                                                                                                                                James Dalton
                                                                ,
                                                                                                                                Xavier Rovira
                                                                ,
                                                                                                                                Jean-Philippe Pin
                                                                ,
                                                                                                                                Cyril Goudet
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-02066019
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Illuminating Phenylazopyridines To Photoswitch Metabotropic Glutamate Receptors: From the Flask to the Animals
        
                            
                                                                                                            Xavier Gómez-Santacana
                                                                ,
                                                                                                                                Silvia Pittolo
                                                                ,
                                                                                                                                Xavier Rovira
                                                                ,
                                                                                                                                Marc Lopez
                                                                ,
                                                                                                                                Charleine Zussy
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-02066097
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            OptoGluNAM4.1, a Photoswitchable Allosteric Antagonist for Real-Time Control of mGlu4 Receptor Activity
        
                            
                                                                                                            Xavier Rovira
                                                                ,
                                                                                                                                Ana Trapero
                                                                ,
                                                                                                                                Silvia Pittolo
                                                                ,
                                                                                                                                Charleine Zussy
                                                                ,
                                                                                                                                Adèle Faucherre
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-01941168
                                            v1
                                    
            
        
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            New 4-Functionalized Glutamate Analogues Are Selective Agonists at Metabotropic Glutamate Receptor Subtype 2 or Selective Agonists at Metabotropic Glutamate Receptor Group III
        
                            
                                                                                                            Tri H. V. Huynh
                                                                ,
                                                                                                                                Mette N. Erichsen
                                                                ,
                                                                                                                                Amélie S. Tora
                                                                ,
                                                                                                                                Cyril Goudet
                                                                ,
                                                                                                                                Emmanuelle Sagot
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-01288609
                                            v1
                                    
            
        
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    | 
        
                                                 
                        
                     
                                    
     | 
        
        
            Shining Light on an mGlu5 Photoswitchable NAM: A Theoretical Perspective
        
                            
                                                                                                            James Dalton
                                                                ,
                                                                                                                                Isaias Lans
                                                                ,
                                                                                                                                Xavier Rovira
                                                                ,
                                                                                                                                Fanny Malhaire
                                                                ,
                                                                                                                                Xavier Gómez-Santacana
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-02448289
                                            v1
                                    
            
        
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    | 
        
                            
                    
     | 
        
        
            Therapeutic potential of group III metabotropic glutamate receptor ligands in pain
        
                            
                                                                                                            Francine Acher
                                                                ,
                                                                                                                                Cyril Goudet
                                                                                    
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-01950127
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                                                
     | 
        
        
            Determination of the absolute configuration of phosphinic analogues of glutamate
        
                            
                                                                                                            Bruno Commare
                                                                ,
                                                                                                                                Delphine Rigault
                                                                ,
                                                                                                                                Isabelle Lemasson
                                                                ,
                                                                                                                                Patrick Deschamps
                                                                ,
                                                                                                                                Alain Tomas
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-02268872
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                                                
     | 
        
        
            Overlapping binding sites drive allosteric agonism and positive cooperativity in type 4 metabotropic glutamate receptors
        
                            
                                                                                                            Xavier Rovira
                                                                ,
                                                                                                                                Fanny Malhaire
                                                                ,
                                                                                                                                Pauline Scholler
                                                                ,
                                                                                                                                Jordi Rodrigo
                                                                ,
                                                                                                                                P. Gonzalez-Bulnes
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-01943324
                                            v1
                                    
            
        
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    | 
        
                                                
     | 
        
        
            Synthesis and studies on the mGluR agonist activity of FAP4 stereoisomers
        
                            
                                                                                                            Pavel Ivashkin
                                                                ,
                                                                                                                                Gérald Lemonnier
                                                                ,
                                                                                                                                Amélie S. Tora
                                                                ,
                                                                                                                                Jean-Philippe Pin
                                                                ,
                                                                                                                                Cyril Goudet
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-01180138
                                            v1
                                    
            
        
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     | 
        
        
            Allosteric modulation of metabotropic glutamate receptors by chloride ions
        
                            
                                                                                                            Amélie S. Tora
                                                                ,
                                                                                                                                Xavier Rovira
                                                                ,
                                                                                                                                Ibrahima Dione
                                                                ,
                                                                                                                                Hugues-Olivier Bertrand
                                                                ,
                                                                                                                                Isabelle Brabet
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-02065116
                                            v1
                                    
            
        
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     | 
        
        
            Exploring the active conformation of cyclohexane carboxylate positive allosteric modulators of the type 4 metabotropic glutamate receptor
        
                            
                                                                                                            Xavier Rovira
                                                                ,
                                                                                                                                Youssef Harrak
                                                                ,
                                                                                                                                Ana Trapero
                                                                ,
                                                                                                                                Patricia Gonzalez-Bulnes
                                                                ,
                                                                                                                                Fanny Malhaire
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
                    istex
        
        
            
                
                    hal-01943327
                                            v1
                                    
            
        
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            An allosteric modulator to control endogenous G protein-coupled receptors with light
        
                            
                                                                                                            S. Pittolo
                                                                ,
                                                                                                                                X. Gomez-Santacana
                                                                ,
                                                                                                                                K. Eckelt
                                                                ,
                                                                                                                                Xavier Rovira
                                                                ,
                                                                                                                                J. Dalton
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-01942934
                                            v1
                                    
            
        
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    | 
        
                            
                    
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            Alleviating Pain Hypersensitivity through Activation of Type 4 Metabotropic Glutamate Receptor
        
                            
                                                                                                            Bruno Vilar
                                                                ,
                                                                                                                                Jérôme Busserolles
                                                                ,
                                                                                                                                Bing Ling
                                                                ,
                                                                                                                                Sophie Laffray
                                                                ,
                                                                                                                                Lauriane Ulmann
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-02448295
                                            v1
                                    
            
        
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     | 
        
        
            A novel selective metabotropic glutamate receptor 4 agonist reveals new possibilities for developing subtype selective ligands with therapeutic potential.
        
                            
                                                                                                            Cyril Goudet
                                                                ,
                                                                                                                                Bruno Vilar
                                                                ,
                                                                                                                                Tiphanie Courtiol
                                                                ,
                                                                                                                                Thierry Deltheil
                                                                ,
                                                                                                                                Thomas Bessiron
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-01182946
                                            v1
                                    
            
        
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     | 
        
        
            Α-amino-β-fluorocyclopropanecarboxylic acids as a new tool for drug development: synthesis of glutamic acid analogs and agonist activity towards metabotropic glutamate receptor 4.
        
                            
                                                                                                            Gérald Lemonnier
                                                                ,
                                                                                                                                Cédric Lion
                                                                ,
                                                                                                                                Jean-Charles Quirion
                                                                ,
                                                                                                                                Jean-Philippe Pin
                                                                ,
                                                                                                                                Cyril Goudet
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
                    istex
        
        
            
                
                    hal-00996602
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                                                
     | 
        
        
            Cinnabarinic Acid, an Endogenous Metabolite of the Kynurenine Pathway, Activates Type 4 Metabotropic Glutamate Receptors
        
                            
                                                                                                            F. Fazio
                                                                ,
                                                                                                                                L. Lionetto
                                                                ,
                                                                                                                                G. Molinaro
                                                                ,
                                                                                                                                H. Bertrand
                                                                ,
                                                                                                                                F. Acher
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-02448364
                                            v1
                                    
            
        
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    | 
        
                                                
     | 
        
        
            A new Selective Metabotropic Glutamate Receptor type 4 Agonist Reveals New ways to Develop Subtype Selective Orthosteric Ligands with Potential Therapeutic Effects
        
                            
                                                                                                            Cyril Goudet
                                                                ,
                                                                                                                                Bruno Vilar
                                                                ,
                                                                                                                                Tiphanie Courtiol
                                                                ,
                                                                                                                                Thierry Deltheil
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                                                                                                                                Thomas Bessiron
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                            Current Neuropharmacology, 2011, 9 (1), pp.26 
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                    hal-01384798
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            Is metabotropic glutamate receptor mGlu4R a good target to treat Parkinson's disease symptoms? Design and evaluation of potent and selective agonists
        
                            
                                                                                                            Isabelle A. Lemasson
                                                                ,
                                                                                                                                Chelliah Selvam
                                                                ,
                                                                                                                                Nadia Oueslati
                                                                ,
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                            Abstracts of Papers of the American Chemical Society, 2009, 238 
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                    hal-01384832
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            LSP1-2111, a new orthosteric group III mGlur agonist with preferential activity on mGluR4, modulates the striatopallidal synapse and alleviates parkinsonian symptoms
        
                            
                                                                                                            C. Beurrier
                                                                ,
                                                                                                                                D. Revy
                                                                ,
                                                                                                                                S. Lopez
                                                                ,
                                                                                                                                M. Lherondel
                                                                ,
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                    hal-01384860
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            N-{4-Chloro-2-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]phenyl}-2-hydroxybenzamide (CPPHA) acts through a novel site as a positive allosteric modulator of group 1 metabotropic glutamate receptors.
        
                            
                                                                                                            Yelin Chen
                                                                ,
                                                                                                                                Cyril Goudet
                                                                ,
                                                                                                                                Jean-Philippe Pin
                                                                ,
                                                                                                                                P Jeffrey Conn
                                                                                    
                 
                            
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                    inserm-00318958
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            L-(+)-2-Amino-4-thiophosphonobutyric acid (L-thioAP4), a new potent agonist of group III metabotropic glutamate receptors: increased distal acidity affords enhanced potency.
        
                            
                                                                                                            Chelliah Selvam
                                                                ,
                                                                                                                                Cyril Goudet
                                                                ,
                                                                                                                                Nadia Oueslati
                                                                ,
                                                                                                                                Jean-Philippe Pin
                                                                ,
                                                                                                                                Francine C. Acher
                                                                                    
                 
                            
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                    inserm-00318965
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            Interaction of novel positive allosteric modulators of metabotropic glutamate receptor 5 with the negative allosteric antagonist site is required for potentiation of receptor responses.
        
                            
                                                                                                            Yelin Chen
                                                                ,
                                                                                                                                Yi Nong
                                                                ,
                                                                                                                                Cyril Goudet
                                                                ,
                                                                                                                                Kamondanai Hemstapat
                                                                ,
                                                                                                                                Tomas de Paulis
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                    inserm-00319012
                                            v1
                                    
            
        
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            Synthesis and biological evaluation of 1-amino-2-phosphonomethylcyclopropanecarboxylic acids, new group III metabotropic glutamate receptor agonists.
        
                            
                                                                                                            Pauline Sibille
                                                                ,
                                                                                                                                Sébastien Lopez
                                                                ,
                                                                                                                                Isabelle Brabet
                                                                ,
                                                                                                                                Ornella Valenti
                                                                ,
                                                                                                                                Nadia Oueslati
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                    inserm-00318976
                                            v1
                                    
            
        
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            Group III metabotropic glutamate receptors inhibit hyperalgesia in animal models of inflammation and neuropathic pain
        
                            
                                                                                                            Cyril Goudet
                                                                ,
                                                                                                                                Eric Chapuy
                                                                ,
                                                                                                                                Abdelkrim Alloui
                                                                ,
                                                                                                                                Francine Acher
                                                                ,
                                                                                                                                Jean-Philippe Pin
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                    inserm-00318859
                                            v1
                                    
            
        
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            D-myo-inositol 1-phosphate as a surrogate of D-myo-inositol 1,4,5-tris phosphate to monitor G protein-coupled receptor activation.
        
                            
                                                                                                            Eric Trinquet
                                                                ,
                                                                                                                                Michel Fink
                                                                ,
                                                                                                                                Hervé Bazin
                                                                ,
                                                                                                                                Florence Grillet
                                                                ,
                                                                                                                                Fabrice Maurin
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                    inserm-00318996
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            Evidence for a single heptahelical domain being turned on upon activation of a dimeric GPCR.
        
                            
                                                                                                            Veronika Hlavackova
                                                                ,
                                                                                                                                Cyril Goudet
                                                                ,
                                                                                                                                Julie Kniazeff
                                                                ,
                                                                                                                                Alice Zikova
                                                                ,
                                                                                                                                Damien Maurel
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                    inserm-00318934
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            Allosteric functioning of dimeric class C G-protein-coupled receptors.
        
                            
                                                                                                            Jean-Philippe Pin
                                                                ,
                                                                                                                                Julie Kniazeff
                                                                ,
                                                                                                                                Jianfeng Liu
                                                                ,
                                                                                                                                Virginie Binet
                                                                ,
                                                                                                                                Cyril Goudet
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                    inserm-00094959
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            Asymmetric functioning of dimeric metabotropic glutamate receptors disclosed by positive allosteric modulators.
        
                            
                                                                                                            Cyril Goudet
                                                                ,
                                                                                                                                Julie Kniazeff
                                                                ,
                                                                                                                                Veronika Hlavackova
                                                                ,
                                                                                                                                Fanny Malhaire
                                                                ,
                                                                                                                                Damien Maurel
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                    inserm-00318925
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            Heptahelical domain of metabotropic glutamate receptor 5 behaves like rhodopsin-like receptors.
        
                            
                                                                                                            Cyril Goudet
                                                                ,
                                                                                                                                Florence Gaven
                                                                ,
                                                                                                                                Julie Kniazeff
                                                                ,
                                                                                                                                Claire Vol
                                                                ,
                                                                                                                                Jianfeng Liu
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                            Proceedings of the National Academy of Sciences of the United States of America, 2004, 101 (1), pp.378-83.  ⟨10.1073/pnas.0304699101⟩ 
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                    inserm-00319003
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            Locking the dimeric GABA(B) G-protein-coupled receptor in its active state.
        
                            
                                                                                                            Julie Kniazeff
                                                                ,
                                                                                                                                Pierre-Philippe Saintot
                                                                ,
                                                                                                                                Cyril Goudet
                                                                ,
                                                                                                                                Jianfeng Liu
                                                                ,
                                                                                                                                Annie Charnet
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                    hal-00319013
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            Magnesium ions promote assembly of channel-like structures from beticolin o, a non-peptide fungal toxin purified from Cercospora beticola
        
                            
                                                                                                            Cyril Goudet
                                                                ,
                                                                                                                                Anne-Aliénor Véry
                                                                ,
                                                                                                                                M.L. Milat
                                                                ,
                                                                                                                                M. Ildefonse
                                                                ,
                                                                                                                                Jean-Baptiste Thibaud
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                    hal-02690441
                                            v1
                                    
            
        
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