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Straightforward Access to a New Class of Dual DYRK1A/CLK1 Inhibitors Possessing a Simple Dihydroquinoline Core
Mihaela-Liliana Ţînţaş
,
Ludovic Peauger
,
Florent Alix
,
Cyril Papamicaël
,
Thierry Besson
et al.
Article dans une revue
hal-03922046
v1
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Chemical Delivery System of MIBG to the Central Nervous System: Synthesis, 11 C-Radiosynthesis, and in Vivo Evaluation
Fabienne Gourand
,
Delphine Patin
,
Axelle Henry
,
Meźiane Ibazizeǹe
,
Martine Dhilly
et al.
Article dans une revue
hal-03020265
v1
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Design, Synthesis, and In Vitro Biological Activities of a Bio-Oxidizable Prodrug to Deliver Both ChEs and DYRK1A Inhibitors for AD Therapy
Anaïs Barré
,
Rabah Azzouz
,
Vincent Gembus
,
Cyril Papamicaël
,
Vincent Levacher
Article dans une revue
hal-03134351
v1
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Rational design of carbamate-based dual binding site and central AChE inhibitors by a “biooxidisable” prodrug approach: Synthesis, in vitro evaluation and docking studies
Mihaela-Liliana Ţînţaş
,
Vincent Gembus
,
Florent Alix
,
Anaïs Barré
,
Gaël Coadou
et al.
Article dans une revue
hal-03134356
v1
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Access to Highly Enantioenriched Donepezil-like 1,4-Dihydropyridines as Promising Anti-Alzheimer Prodrug Candidates via Enantioselective Tsuji Allylation and Organocatalytic Aza-Ene-Type Domino Reactions
Mihaela-Liliana Ţînţaş
,
Rabah Azzouz
,
Ludovic Peauger
,
Vincent Gembus
,
Emilie Petit
et al.
Article dans une revue
hal-03134345
v1
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Novel donepezil-like N-benzylpyridinium salt derivatives as AChE inhibitors and their corresponding dihydropyridine “bio-oxidizable” prodrugs: Synthesis, biological evaluation and structure-activity relationship
Rabah Azzouz
,
Ludovic Peauger
,
Vincent Gembus
,
Mihaela-Liliana Tîntas
,
Jana Sopkova-de Oliveira Santos
et al.
Article dans une revue
hal-02043695
v1
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Dihydroquinoline Carbamate DQS1-02 as a Prodrug of a Potent Acetylcholinesterase Inhibitor for Alzheimer’s Disease Therapy: Multigram-Scale Synthesis, Mechanism Investigations, in Vitro Safety Pharmacology, and Preliminary in Vivo Toxicology Profile
Florent Alix
,
Vincent Gembus
,
Laurent Coquet
,
Marie Hubert-Roux
,
Philippe Chan
et al.
Article dans une revue
hal-03134333
v1
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Delivering FLT to the Central Nervous System by Means of a Promising Targeting System: Synthesis, [11C]Radiosynthesis, and in Vivo Evaluation
Fabienne Gourand
,
Mihaela-Liliana Tîntas
,
Axelle Henry
,
Méziane Ibazizène
,
Martine Dhilly
et al.
Article dans une revue
hal-02046279
v1
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Donepezil-Based Central Acetylcholinesterase Inhibitors by Means of a “Bio-Oxidizable” Prodrug Strategy: Design, Synthesis, and in Vitro Biological Evaluation
Ludovic Peauger
,
Rabah Azzouz
,
Vincent Gembus
,
Mihaela-Liliana Ţînţaş
,
Jana Sopkova-de Oliveira Santos
et al.
Article dans une revue
hal-02043729
v1
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An Overview of the Synthesis of Highly Versatile N-Hydroxysuccinimide Esters
Anaïs Barré
,
Mihaela-Liliana Tîntas
,
Vincent Levacher
,
Cyril Papamicaël
,
Vincent Gembus
Article dans une revue
hal-02046258
v1
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The Influence of Amino Group Position on Aryl Moiety of SarAr on Metal Complexation and Protein Labelling
Vincent Jamier
,
Eskender Mume
,
Cyril Papamicaël
,
Suzanne V. Smith
Article dans une revue
hal-02046216
v1
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Dihydroquinoline Carbamate Derivatives as "Bio-oxidizable" Prodrugs for Brain Delivery of Acetylcholinesterase Inhibitors: [¹¹C] Radiosynthesis and Biological Evaluation
Pierre Bohn
,
F. Gourand
,
Cyril Papamicaël
,
M. Ibazizène
,
M Dhilly
et al.
Article dans une revue
hal-01578046
v1
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Palladium-Catalyzed Carbonylation of (Hetero)Aryl, Alkenyl and Allyl Halides by Means of N-Hydroxysuccinimidyl Formate as CO Surrogate
Anaïs Barré
,
Mihaela-Liliana Tîntas
,
Florent Alix
,
Vincent Gembus
,
Cyril Papamicaël
et al.
Article dans une revue
hal-02046139
v1
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New developments in redox chemical delivery systems by means of 1,4-dihydroquinoline-based targetor: Application to galantamine delivery to the brain
Mihaela-Liliana Tîntas
,
Lénaïg Foucout
,
Sylvain Petit
,
Sylvain Oudeyer
,
Fabienne Gourand
et al.
Article dans une revue
hal-03856118
v1
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New developments in redox chemical delivery systems by means of 1,4-dihydroquinoline-based targetor: Application to galantamine delivery to the brain
Mihaela-Liliana Tîntas
,
Lénaïg Foucout
,
Sylvain Petit
,
Sylvain Oudeyer
,
Fabienne Gourand
et al.
Article dans une revue
hal-01141464
v1
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Synthesis and Stability Evaluation of New HYNIC Derivatives as Ligands for Technetium-99m
Yoann Joyard
,
Laurent Bischoff
,
Vincent Levacher
,
Cyril Papamicaël
,
Pierre Vera
et al.
Article dans une revue
hal-01141349
v1
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Synthesis of sulfonic acid derivatives by oxidative deprotection of thiols using tert-butyl hypochlorite
Yoann Joyard
,
Cyril Papamicaël
,
Pierre Bohn
,
Laurent Bischoff
Article dans une revue
hal-00997432
v1
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Synthesis and biological evaluation of a novel (99m)Tc labeled 2-nitroimidazole derivative as a potential agent for imaging tumor hypoxia.
Yoann Joyard
,
Vadim Le Joncour
,
Hélène Castel
,
Chérif Bounana Diouf
,
Laurent Bischoff
et al.
Article dans une revue
istex
hal-00997430
v1
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Synthesis of new 18F-radiolabeled silicon-based nitroimidazole compounds.
Yoann Joyard
,
Rabah Azzouz
,
Laurent Bischoff
,
Cyril Papamicaël
,
Daniel Labar
et al.
Article dans une revue
istex
hal-00997431
v1
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Rational design of central selective acetylcholinesterase inhibitors by means of a "bio-oxidisable prodrug" strategy.
Pierre Bohn
,
Nicolas Le Fur
,
Guillaume Hagues
,
Jean Costentin
,
Nicolas Torquet
et al.
Article dans une revue
istex
inserm-00467214
v1
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|
A rapid synthesis of new benzene-centered porphyrin trimers.
C.A. Papamicaël
,
O. Mongin
,
A. Gossauer
J. Heterocyclic Chem., 2007, 44, pp.1071-1076
Article dans une revue
hal-00323063
v1
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Synthesis of C1- and C3m-Symmetric Porphyrin Trimers Based on Triphenylmethane Cores
Cyril Papamicaël
,
Olivier Mongin
,
A. Gossauer
Article dans une revue
istex
hal-00842774
v1
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Synthesis of C1- and C3v-Symmetric Porphyrin Trimers Based on Triphenylmethane Cores
C.A. Papamicaël
,
O. Mongin
,
A. Gossauer
Chemical Monthly = Monatshefte für Chemie, 2007, 138, pp.791-796
Article dans une revue
hal-00323182
v1
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Preparation of new axially chiral bridged 2,2′-bipyridines and pyridyl monooxazolines (pymox). Evaluation in copper( i )-catalyzed enantioselective cyclopropanation
Alexis Bouet
,
Barbara Heller
,
Cyril Papamicaël
,
Georges Dupas
,
Sylvain Oudeyer
et al.
Article dans une revue
istex
hal-02278796
v1
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New development of meyers' methodology : stereoselective preparation of an axially chiral 5,7-fused bicyclic lactam related to circumdatins/benzomalvins and asperlicins.
M. Penhoat
,
Pierre Bohn
,
G. Dupas
,
C. Papamicaël
,
Francis Marsais
et al.
Tetrahedron: Asymmetry, 2006, pp.281-6
Article dans une revue
hal-00475867
v1
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Solid phase synthesis of a redox delivery system with the aim of targeting peptides into the brain.
Claudine Patteux
,
Lénaïg Foucout
,
Pierre Bohn
,
Georges Dupas
,
Jérôme Leprince
et al.
Article dans une revue
istex
inserm-00475858
v1
|
|
Synthesis of Various Terphenyl Derivatives; Study of a New Amine Receptor with a Terphenyl Structure
Patricia Le Nahenec-Martel
,
Stéphane Leleu
,
Francis Marsais
,
Cyril Papamicaël
,
Vincent Levacher
et al.
Article dans une revue
hal-02547629
v1
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Chemoselective, accelerated and stereoselective aza-Michael addition of amines to N-phenylmaleimide by using TMEDA based receptors
Yuefeng Bi
,
Laëtitia Bailly
,
Francis Marsais
,
Vincent Levacher
,
Cyril Papamicaël
et al.
Article dans une revue
istex
hal-02378309
v1
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The Inhibitor Thiomandelic Acid Binds to Both Metal Ions in Metallo-β-lactamase and Induces Positive Cooperativity in Metal Binding
Christian Damblon
,
Mikael Jensen
,
Abdessamad Ababou
,
Igor Barsukov
,
Cyril Papamicaël
et al.
Article dans une revue
hal-03856336
v1
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Three-dimensional Structure of FEZ-1, a Monomeric Subclass B3 Metallo-β-lactamase from Fluoribacter gormanii, in Native Form and in Complex with d-Captopril
I Garcı́a-Sáez
,
P S Mercuri
,
Cyril Papamicaël
,
R Kahn
,
J M Frère
et al.
Article dans une revue
hal-03856347
v1
|
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The 1.5-Å structure of $Chryseobacterium\ meningosepticum$ zinc β-lactamase in complex with the inhibitor, D-Captopril
Isabel García-Sáez
,
Julie Hopkins
,
Cyril Papamicaël
,
Nicola Franceschini
,
Gianfranco Amicosante
et al.
Article dans une revue
hal-03856326
v1
|
|
Thiomandelic acid, a broad spectrum inhibitor of zinc beta-lactamases: kinetic and spectroscopic studies.
C. Mollard
,
C. Moali
,
C. Papamicael
,
C. Damblon
,
S. Vessilier
et al.
Journal of Biological Chemistry, 2001, 276, pp.45015-45023
Article dans une revue
hal-00314477
v1
|
|
Thiomandelic Acid, a Broad Spectrum Inhibitor of Zinc β-Lactamases
Claire Mollard
,
Catherine Moali
,
Cyril Papamicaël
,
Christian Damblon
,
Sandrine Vessilier
et al.
Article dans une revue
hal-03856340
v1
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